CN207667285U - A kind of chromatographic apparatus in human serum albumin production - Google Patents

A kind of chromatographic apparatus in human serum albumin production Download PDF

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Publication number
CN207667285U
CN207667285U CN201721789230.6U CN201721789230U CN207667285U CN 207667285 U CN207667285 U CN 207667285U CN 201721789230 U CN201721789230 U CN 201721789230U CN 207667285 U CN207667285 U CN 207667285U
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Prior art keywords
slide bar
hole
slot
filter
locating
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CN201721789230.6U
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Chinese (zh)
Inventor
邓志华
庞跃林
吴志韡
赵睿
钟世平
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Guangdong Danxia Biological Pharmaceutical Co ltd
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Guangdong Danxia Biological Pharmaceutical Co ltd
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Abstract

A kind of chromatographic apparatus in being produced the utility model discloses human serum albumin, including device body, through-hole is offered on described device ontology, through-hole is slidably fitted with chromatographic column, the top of chromatographic column extends to outside through-hole, filter is slidably fitted in through-hole, filter is located at the lower section of chromatographic column, slide bar through-hole is offered on the inner wall of through-hole both sides, it is slidably fitted with slide bar in slide bar through-hole, and the both ends of slide bar all extend to outside slide bar through-hole, the both sides of filter offer the fixing groove in through-hole, slide bar is slidably connected close to one end of filter with fixing groove, positioning rod slot is offered on the inner wall of slide bar through-hole top side, locating rod is slidably fitted in positioning rod slot, and the bottom end of locating rod extends to outside positioning rod slot.The utility model is simple in structure, easy to use, can be easy to operate by filter fast assembling-disassembling, saves the time, improves work efficiency.

Description

A kind of chromatographic apparatus in human serum albumin production
Technical field
The utility model is related to the chromatography dresses in chromatographic apparatus technical field more particularly to a kind of production of human serum albumin It sets.
Background technology
Chromatography is the difference using each component physical property, and multicomponent mixture is carried out separation and method for measuring, is had Two kinds of adsorption chromatography, Partition Chromatography, are generally used for the analysis of organic compound, metal ion, amino acid etc., and chromatography utilizes substance The different allocation proportion between stationary phase and mobile phase reaches the technology of separation purpose, chromatographs to large biological molecule such as albumen The separation analysis of the mixture of the organic matter of the complexity such as matter and nucleic acid has high resolving power.
Currently, the filter majority of existing chromatographic apparatus is all to be fixedly mounted, carrying out to cleaning filter and replacement When it is very troublesome, it is necessary to could be completed by the tool of profession, waste time, be unfavorable for the operation of staff, with The progress of science and technology, social development, more stringent requirements are proposed to chromatographic apparatus by people, so, we have proposed one kind Chromatographic apparatus in human serum albumin production is for solving the above problems.
Utility model content
Purpose of the utility model is to solve disadvantages existing in the prior art, and a kind of human serum albumin proposed Chromatographic apparatus in production.
To achieve the goals above, the utility model uses following technical solution:
Chromatographic apparatus in a kind of production of human serum albumin, including device body offer through-hole on described device ontology, Through-hole is slidably fitted with chromatographic column, and the top of chromatographic column extends to outside through-hole, and filter, filter position are slidably fitted in through-hole In offering slide bar through-hole on the lower section of chromatographic column, the inner wall of through-hole both sides, slide bar is slidably fitted in slide bar through-hole, and sliding The both ends of bar all extend to outside slide bar through-hole, and the both sides of filter offer the fixing groove in through-hole, and slide bar is close to mistake One end of filter is slidably connected with fixing groove;
Positioning rod slot is offered on the inner wall of slide bar through-hole top side, locating rod is slidably fitted in positioning rod slot, and position The bottom end of bar extends to outside positioning rod slot, and the top side of slide bar offers the first locating slot in slide bar through-hole, locating rod Bottom end is slidably connected with the first locating slot, and the top side of slide bar offers the second locating slot, and the second locating slot is located at locating rod to be slided One end in rod through-hole is adapted, and the second locating slot is between the first locating slot and through-hole, and positioning rod slot is far from through-hole side Inner wall on offer pull rod slot, pull rod is slidably fitted in pull rod slot, and one end of pull rod extends to outside pull rod slot, pull rod position It is welded and fixed in one end in pull rod slot and between locating rod.
Preferably, it is installed with the first sliding rail on the inner wall of the through-hole both sides, the both sides of filter are welded with First sliding block, two the first sliding blocks are slidably mounted on respectively in two the first sliding rails.
Preferably, it is installed with the second sliding rail on the inner wall of slide bar through-hole both sides, the both sides of slide bar are welded There are the second sliding block, two the second sliding blocks to be slidably mounted on respectively in two the second sliding rails.
Preferably, the first limiting slot is offered on the inner wall of slide bar through-hole both sides, the first limiting slot is far from filtering The first spring being set on slide bar is welded on the inner wall of device side, fixing sleeve is equipped in the first limiting slot on slide bar First limited block is welded and fixed between the first limited block and the first spring.
Preferably, the second limiting slot is offered on the inner wall of the positioning rod slot both sides, the second limiting slot is far from slide bar The second spring being arranged on the securing lever is welded on the inner wall of side, fixing sleeve is equipped in the second limiting slot in locating rod The second limited block, be welded and fixed between the second limited block and second spring.
Preferably, non-slip mat is fixedly mounted on the inner wall of first locating slot, non-slip mat is in contact with locating rod.
Preferably, it is rolled on the inner wall of the positioning rod slot both sides and ball is installed, ball is in contact with locating rod.
Compared with prior art, the utility model has the beneficial effects that:
In the utility model, by device body, through-hole, chromatographic column, filter, slide bar through-hole, slide bar, fixing groove, determine The cooperation of position bar slot, locating rod, the first locating slot, the second locating slot, pull rod slot and pull rod, when needing to dismantle filter When, first, pull rod is pulled, makes pull rod upward sliding, pull rod drives locating rod to be slided to the direction far from slide bar, when pull rod is from the When being skidded off in a positioning groove, slide bar is pulled, so that slide bar is slided to the direction far from filter, when slide bar is skidded off out of fixing groove When, the second locating slot is aligned with positioning rod slot, releasing lever, under the action of second spring, locating rod is to close to slide bar Direction slide and enter the second locating slot, fixed slip bar makes filter to the side far from chromatographic column at this point, pulling filter To sliding, when filter fully slides out out of through-hole, the dismantlement work of filter is completed, when needing to pacify filter When dress, first, filter and through-hole are slidably connected, so that filter is slided to close to the direction of chromatographic column, when sliding into fixation When slot aligns with slide bar through-hole, pull rod is pulled, makes pull rod upward sliding, pull rod that locating rod be driven to be slided to the direction far from slide bar Dynamic, when locating rod is skidded off out of second locating slot, under the action of the first spring, slide bar is slided to close to the direction of filter And entering fixing groove, Fixed-Filter aligns the first locating slot with positioning rod slot, releasing lever, in the work of second spring Under, the first locating slot, fixed slip bar, so as to complete the peace of filter are slided and entered to locating rod to the direction close to slide bar The fixed work of dress, the utility model is simple in structure, easy to use, can be easy to operate by filter fast assembling-disassembling, when saving Between, it improves work efficiency.
Description of the drawings
Fig. 1 be the utility model proposes a kind of human serum albumin production in chromatographic apparatus structural schematic diagram;
Fig. 2 be the utility model proposes a kind of human serum albumin production in chromatographic apparatus part A structural schematic diagram;
Fig. 3 be the utility model proposes a kind of human serum albumin production in chromatographic apparatus slide bar stereochemical structure signal Figure.
In figure:1 device body, 2 through-holes, 3 chromatographic columns, 4 filters, 5 slide bar through-holes, 6 slide bars, 7 fixing grooves, 8 locating rods Slot, 9 locating rods, 10 first locating slots, 11 second locating slots, 12 pull rod slot, 13 pull rods.
Specific implementation mode
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.
Referring to Fig.1-3, the chromatographic apparatus in a kind of production of human serum albumin, including device body 1 are opened on device body 1 Equipped with through-hole 2, through-hole 2 is slidably fitted with chromatographic column 3, and the top of chromatographic column 3 extends to outside through-hole 2, is slidably fitted in through-hole 2 Filter 4, filter 4 are located at the lower section of chromatographic column 3, slide bar through-hole 5, slide bar through-hole 5 are offered on the inner wall of 2 both sides of through-hole It is inside slidably fitted with slide bar 6, and the both ends of slide bar 6 all extend to outside slide bar through-hole 5, the both sides of filter 4, which offer, to be located at Fixing groove 7 in through-hole 2, slide bar 6 are slidably connected close to one end of filter 4 and fixing groove 7;
Positioning rod slot 8 is offered on the inner wall of 5 top side of slide bar through-hole, and locating rod 9 is slidably fitted in positioning rod slot 8, and The bottom end of locating rod 9 extends to outside positioning rod slot 8, and the top side of slide bar 6 offers the first locating slot in slide bar through-hole 5 10, the bottom end of locating rod 9 is slidably connected with the first locating slot 10, and the top side of slide bar 6 offers the second locating slot 11, the second positioning Slot 11 is located at one end in slide bar through-hole 5 with locating rod 9 and is adapted, and the second locating slot 11 is located at the first locating slot 10 and through-hole 2 Between, positioning rod slot 8 offers pull rod slot 12 on the inner wall far from 2 side of through-hole, pull rod 13 is slidably fitted in pull rod slot 12, And one end of pull rod 13 extends to outside pull rod slot 12, pull rod 13 is located at one end in pull rod slot 12 and is welded between locating rod 9 solid It is fixed, pass through device body 1, through-hole 2, chromatographic column 3, filter 4, slide bar through-hole 5, slide bar 6, fixing groove 7, positioning rod slot 8, positioning The cooperation of bar 9, the first locating slot 10, the second locating slot 11, pull rod slot 12 and pull rod 13, when needing to dismantle filter 4 When, first, pull rod 13 is pulled, makes 13 upward sliding of pull rod, pull rod 13 that locating rod 9 be driven to be slided to the direction far from slide bar 6, when When pull rod 13 is skidded off out of first locating slot 10, slide bar 6 is pulled, so that slide bar 6 is slided to the direction far from filter 4, when slide bar 6 When being skidded off out of fixing groove 7, the second locating slot 11 is aligned with positioning rod slot 8, releasing lever 13, in the effect of second spring Under, the second locating slot 11, fixed slip bar 6 are slided and entered to locating rod 9 to close to the direction of slide bar 6, at this point, filter 4 is pulled, So that filter 4 is slided to the direction far from chromatographic column 3, when filter 4 fully slides out out of through-hole 2, completes filter 4 First, filter 4 is slidably connected with through-hole when needing to be installed filter 4 for dismantlement work, make filter 4 to by The direction sliding of nearly chromatographic column 3 pulls pull rod 13 when sliding into fixing groove 7 and aligning with slide bar through-hole 5, make pull rod 13 to Upper sliding, pull rod 13 drives locating rod 9 to be slided to the direction far from slide bar 6, when locating rod 9 is skidded off out of second locating slot 11 When, under the action of the first spring, slide bar 6 slides and enters fixing groove 7 to close to the direction of filter 4, Fixed-Filter 4, First locating slot 10 is aligned with positioning rod slot 8, releasing lever 13, under the action of second spring, locating rod 9 is to close to sliding The first locating slot 10 is slided and enters in the direction of bar 6, and fixed slip bar 6 fixes work so as to complete the installation of filter 4, this Utility model is simple in structure, easy to use, can be easy to operate by 4 fast assembling-disassembling of filter, saves the time, improves work Efficiency.
The first sliding rail is installed on the inner wall of 2 both sides of through-hole, the both sides of filter 4 are welded with the first sliding block, Two the first sliding blocks are slidably mounted on respectively in two the first sliding rails, and is installed on the inner wall of 5 both sides of slide bar through-hole The both sides of two sliding rails, slide bar 6 are welded with the second sliding block, and two the second sliding blocks are slidably mounted on respectively in two the second sliding rails, The first limiting slot is offered on the inner wall of 5 both sides of slide bar through-hole, the first limiting slot welds on the inner wall far from 4 side of filter There is the first spring being set on slide bar 6, fixing sleeve is equipped with the first limited block being located in the first limiting slot on slide bar 6, and first It is welded and fixed between limited block and the first spring, the second limiting slot, the second limit is offered on the inner wall of 8 both sides of positioning rod slot Slot is welded with the second spring being set in locating rod 9 on the inner wall far from 6 side of slide bar, fixing sleeve is equipped with position in locating rod 9 In the second limited block in the second limiting slot, be welded and fixed between the second limited block and second spring, the first locating slot 10 it is interior Non-slip mat is fixedly mounted on wall, non-slip mat is in contact with locating rod 9, is rolled on the inner wall of 8 both sides of positioning rod slot and is equipped with rolling Pearl, ball are in contact with locating rod 9, by device body 1, through-hole 2, chromatographic column 3, filter 4, slide bar through-hole 5, slide bar 6, consolidate The cooperation for determining slot 7, positioning rod slot 8, locating rod 9, the first locating slot 10, the second locating slot 11, pull rod slot 12 and pull rod 13, when need When filter 4 is dismantled, first, pull rod 13 is pulled, makes 13 upward sliding of pull rod, pull rod 13 drives locating rod 9 to remote Direction sliding from slide bar 6 pulls slide bar 6 when pull rod 13 is skidded off out of first locating slot 10, makes slide bar 6 to far from filtering The direction of device 4 is slided, and when slide bar 6 is skidded off out of fixing groove 7, the second locating slot 11 is aligned with positioning rod slot 8, is unclamped and is drawn Bar 13, under the action of second spring, the second locating slot 11 is slided and entered to locating rod 9 to close to the direction of slide bar 6, fixed to slide Bar 6 makes filter 4 be slided to the direction far from chromatographic column 3 at this point, pulling filter 4, when filter 4 is complete out of through-hole 2 When skidding off, the dismantlement work of filter 4 is completed, when needing to be installed filter 4, first, by filter 4 and through-hole It is slidably connected, filter 4 is made to be slided to close to the direction of chromatographic column 3, when sliding into fixing groove 7 and slide bar through-hole 5 aligns, Pull rod 13 is pulled, makes 13 upward sliding of pull rod, pull rod 13 drives locating rod 9 to be slided to the direction far from slide bar 6, when locating rod 9 When being skidded off out of second locating slot 11, under the action of the first spring, slide bar 6 slides and enters to close to the direction of filter 4 Fixing groove 7, Fixed-Filter 4 align the first locating slot 10 with positioning rod slot 8, releasing lever 13, in the work of second spring Under, locating rod 9 is slided to the direction of close slide bar 6 and enters the first locating slot 10, fixed slip bar 6, so as to complete filtering Work is fixed in the installation of device 4, and the utility model is simple in structure, easy to use, can be easy to operate by 4 fast assembling-disassembling of filter, The time is saved, is improved work efficiency.
In the utility model, when needing to be dismantled filter 4, first, pull rod 13 is pulled, pull rod 13 is made to slide up Dynamic, pull rod 13 drives locating rod 9 to be slided to the direction far from slide bar 6, when pull rod 13 is skidded off out of first locating slot 10, pulls Slide bar 6 makes slide bar 6 be slided to the direction far from filter 4, when slide bar 6 is skidded off out of fixing groove 7, by the second locating slot 11 It aligns with positioning rod slot 8, releasing lever 13, under the action of second spring, locating rod 9 is slided to close to the direction of slide bar 6 And entering the second locating slot 11, fixed slip bar 6 makes filter 4 be slided to the direction far from chromatographic column 3 at this point, pulling filter 4 It is dynamic, when filter 4 fully slides out out of through-hole 2, the dismantlement work of filter 4 is completed, when needing to pacify filter 4 When dress, first, filter 4 is slidably connected with through-hole, filter 4 is made to be slided to close to the direction of chromatographic column 3, it is solid when sliding into When determining slot 7 and slide bar through-hole 5 and aligning, pull rod 13 is pulled, makes 13 upward sliding of pull rod, pull rod 13 drives locating rod 9 to separate The direction of slide bar 6 is slided, when locating rod 9 is skidded off out of second locating slot 11, under the action of the first spring, slide bar 6 to by Fixing groove 7 is slided and is entered in the direction of nearly filter 4, and Fixed-Filter 4 aligns the first locating slot 10 with positioning rod slot 8, Releasing lever 13, under the action of second spring, the first locating slot 10 is slided and entered to locating rod 9 to close to the direction of slide bar 6, Fixed slip bar 6 fixes work so as to complete the installation of filter 4.
The preferable specific implementation mode of the above, only the utility model, but the scope of protection of the utility model is not Be confined to this, any one skilled in the art within the technical scope disclosed by the utility model, according to this practicality Novel technical solution and its utility model design are subject to equivalent substitution or change, should all cover the protection model in the utility model Within enclosing.

Claims (7)

1. the chromatographic apparatus in a kind of human serum albumin production, including device body(1), which is characterized in that device body(1)On Offer through-hole(2), through-hole(2)It is slidably fitted with chromatographic column(3), chromatographic column(3)Top extend to through-hole(2)Outside, through-hole (2)Inside it is slidably fitted with filter(4), filter(4)Positioned at chromatographic column(3)Lower section, through-hole(2)It is opened on the inner wall of both sides Equipped with slide bar through-hole(5), slide bar through-hole(5)Inside it is slidably fitted with slide bar(6), and slide bar(6)To all extend to slide bar logical at both ends Hole(5)Outside, filter(4)Both sides offer positioned at through-hole(2)Interior fixing groove(7), slide bar(6)Close to filter(4) One end and fixing groove(7)It is slidably connected;
Slide bar through-hole(5)Positioning rod slot is offered on the inner wall of top side(8), positioning rod slot(8)Inside it is slidably fitted with locating rod (9), and locating rod(9)Bottom end extend to positioning rod slot(8)Outside, slide bar(6)Top side offer positioned at slide bar through-hole(5)It is interior The first locating slot(10), locating rod(9)Bottom end and the first locating slot(10)It is slidably connected, slide bar(6)Top side offer Second locating slot(11), the second locating slot(11)With locating rod(9)Positioned at slide bar through-hole(5)Interior one end is adapted, and second is fixed Position slot(11)Positioned at the first locating slot(10)With through-hole(2)Between, positioning rod slot(8)Far from through-hole(2)It is opened on the inner wall of side Equipped with pull rod slot(12), pull rod slot(12)Inside it is slidably fitted with pull rod(13), and pull rod(13)One end extend to pull rod slot (12)Outside, pull rod(13)Positioned at pull rod slot(12)Interior one end and locating rod(9)Between be welded and fixed.
2. the chromatographic apparatus in a kind of human serum albumin production according to claim 1, which is characterized in that through-hole(2)Two The first sliding rail, filter are installed on the inner wall of side(4)Both sides be welded with the first sliding block, two the first sliding blocks point It is not slidably mounted in two the first sliding rails.
3. the chromatographic apparatus in a kind of human serum albumin production according to claim 1, which is characterized in that slide bar through-hole (5)The second sliding rail, slide bar are installed on the inner wall of both sides(6)Both sides be welded with the second sliding block, two second cunnings Block is slidably mounted on respectively in two the second sliding rails.
4. the chromatographic apparatus in a kind of human serum albumin production according to claim 1, which is characterized in that slide bar through-hole (5)The first limiting slot is offered on the inner wall of both sides, the first limiting slot is far from filter(4)Set is welded on the inner wall of side It is located at slide bar(6)On the first spring, slide bar(6)Upper fixing sleeve be equipped be located at the first limiting slot in the first limited block, first It is welded and fixed between limited block and the first spring.
5. the chromatographic apparatus in a kind of human serum albumin production according to claim 1, which is characterized in that positioning rod slot (8)The second limiting slot is offered on the inner wall of both sides, the second limiting slot is far from slide bar(6)It is welded with and is arranged on the inner wall of side In locating rod(9)On second spring, locating rod(9)Upper fixing sleeve is equipped with the second limited block being located in the second limiting slot, the It is welded and fixed between two limited blocks and second spring.
6. the chromatographic apparatus in a kind of human serum albumin production according to claim 1, which is characterized in that the first locating slot (10)Inner wall on non-slip mat, non-slip mat and locating rod is fixedly mounted(9)It is in contact.
7. the chromatographic apparatus in a kind of human serum albumin production according to claim 1, which is characterized in that positioning rod slot (8)It is rolled on the inner wall of both sides and ball, ball and locating rod is installed(9)It is in contact.
CN201721789230.6U 2017-12-20 2017-12-20 A kind of chromatographic apparatus in human serum albumin production Active CN207667285U (en)

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CN201721789230.6U CN207667285U (en) 2017-12-20 2017-12-20 A kind of chromatographic apparatus in human serum albumin production

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Application Number Priority Date Filing Date Title
CN201721789230.6U CN207667285U (en) 2017-12-20 2017-12-20 A kind of chromatographic apparatus in human serum albumin production

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112582115A (en) * 2020-12-03 2021-03-30 萍乡百斯特电瓷有限公司 To seamless ready-package insulator of formula of tearing open

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112582115A (en) * 2020-12-03 2021-03-30 萍乡百斯特电瓷有限公司 To seamless ready-package insulator of formula of tearing open

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Address after: 512000 Muxi Avenue, Muxi Industrial Park, Shaoguan City, Guangdong Province, 216

Patentee after: Boya Biopharmaceutical (Guangdong) Co., Ltd.

Address before: 512000 Muxi Avenue, Muxi Industrial Park, Shaoguan City, Guangdong Province, 216

Patentee before: Guangdong Danxia biopharmaceutical Co., Ltd.

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Address after: No.216, Muxi Avenue, Muxi Industrial Park, western suburb, Shaoguan City, Guangdong Province

Patentee after: GUANGDONG DANXIA BIOLOGICAL PHARMACEUTICAL Co.,Ltd.

Address before: No.216, Muxi Avenue, Muxi Industrial Park, western suburb, Shaoguan City, Guangdong Province

Patentee before: Boya Biopharmaceutical (Guangdong) Co.,Ltd.