CN207614406U - A kind of high throughput positive-pressure solid-phase extracting device - Google Patents
A kind of high throughput positive-pressure solid-phase extracting device Download PDFInfo
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- CN207614406U CN207614406U CN201721559387.XU CN201721559387U CN207614406U CN 207614406 U CN207614406 U CN 207614406U CN 201721559387 U CN201721559387 U CN 201721559387U CN 207614406 U CN207614406 U CN 207614406U
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Abstract
A kind of high throughput positive-pressure solid-phase extracting device, is characterized in：Including pressure source, rack, panel, pressure regulating unit, Solid Phase Extraction unit and the multiple gas circuit jacks being located on panel；Solid Phase Extraction unit includes multiple Solid Phase Extraction components, and each component is made of vial mating successively, adapter and SPE columns；The pressure regulating unit includes branch air path, pressure adjustment knob, pressure gauge and the gas path on-off switching valve being connected with Solid Phase Extraction unit for being divided into two-way different pressures adjustable range by pressure switching valve；The gas circuit jack on vial docking panel in component realizes the connection of entire gas circuit.The advantages of present apparatus, is：SPE columns are connected by adapter with vial, the pressure adjustable being applied on SPE columns, and SPE columns suitable for various specifications and loading volume it is big, SPE columns flow rate of liquid can control accurate, it realizes that solid phase extraction procedure is simple, efficient, accurate, quick, is suitble to the processing of batch samples.
Description
Technical field
The utility model belongs to extraction equipment technical field, specifically a kind of high throughput positive-pressure solid-phase extracting device, the dress
The pressure for setting achievable two kinds of ranges is adjusted, SPE columns flow rate of liquid can control accurate, make solid phase extraction procedure it is simple, efficiently, it is accurate
Really, quickly, it is suitble to the processing of batch samples.
Background technology
Solid Phase Extraction（Solid phase extraction, SPE）It is a kind of sample pretreatment technology, is mainly used for sample
Separation, purifying and concentration the rate of recovery of analyte can be improved compared with traditional liquid-liquid extraction method, more effectively will analysis
Object is detached with interfering component, reduces sample pretreatment process.It is widely used in the necks such as medicine, food, environment, commodity inspection, chemical industry
Domain.SPE operating procedures include four column pretreatment, sample-adding, elution and elution steps.
The core devices of SPE include SPE extraction equipments and SPE columns.Currently, solid-phase extraction device is divided into negative pressure and positive pressure two
Kind pattern, the single pillar of negative pressure pattern needs independent operation, time-consuming and laborious, and needs to configure the auxiliary such as vacuum pump, sealing surge flask
Component also needs applying power to work.Positive-pressure solid-phase extracting device can once handle tens samples simultaneously, but in its operation
When, sample and solvent can only be packed into SPE columns（cartridge）In, since SPE columns are usually the cylinder of 1~6 mL of volume, elution
When with elution, need that solvent is frequently added, it is cumbersome；For volume be 1 mL SPE column cylinders, can not plus solvent, no
It is suitble to solid-phase extraction device processing.
Invention content
The purpose of this utility model is for the above present situation and a kind of high-throughput positive-pressure solid-phase extracting device for specially designing,
Tens mL solvents can once be added, and it includes 1 mL cylinders to be applicable in different SPE columns, in addition, tens samples can be once handled,
Processing suitable for mass sample.
The purpose of this utility model is achieved through the following technical solutions：
A kind of high throughput positive-pressure solid-phase extracting device, including pressure source, rack, device panel, pressure regulating unit, solid phase
Extraction cells, the gas circuit being connected between Unit two and the multiple gas circuit jacks being arranged on device panel；The Solid Phase Extraction
Unit is arranged in rack on set crane, and Solid Phase Extraction unit includes multiple Solid Phase Extraction components arranged side by side, often
A Solid Phase Extraction component is made of vial mating successively, adapter and SPE columns；The pressure regulating unit includes
By pressure switching valve be divided into the branch air path of two-way different pressures adjustable range, pressure adjustment knob, pressure gauge and with it is solid
The gas path on-off switching valve that phase extraction cells are connected；Vial upper end in Solid Phase Extraction component passes through on docking facilities panel
Gas circuit jack realize the connection of entire gas circuit.
The Solid Phase Extraction unit can be multigroup, and every group includes 12 Solid Phase Extraction components；Every group of Solid Phase Extraction unit is equal
It is connected with pressure regulating unit by gas path on-off switching valve.
Device panel is equipped with three exhaust line jacks, often arranges 12, can amount to simultaneously with three groups of Solid Phase Extraction units and be connected
Tap into row extracting operation.
Two-way different pressures adjustable range is respectively 0~30 psi and 0~160 psi.
Pressure source is compressed air or nitrogen cylinder.
The SPE columns can be the cylinder of different size, include the cylinder of 1~6 mL.
The pressure switching valve, pressure adjustment knob, pressure gauge, gas path on-off switching valve are arranged on device panel.
Solid-phase extraction device is suitable for lessivation extraction and elution process extraction, and difference lies in the former column trickles
Into in liquid waste collector, the column trickle of the latter, which enters in receiving flask, to be retained.
The implementation process of the utility model is as follows：SPE columns, crossover sub and vial are sequentially connected, solvent is added extremely
In vial, lifting bracket switch is pulled upwards, and crane moves up, and crane inputs compressed air by cylinder, realizes two-way fortune
It is dynamic.The gas circuit hole of the embedded panel of vial alignment, pulls pressure switching valve, SPE columns is made to be connected with gas circuit, rotational pressure adjusts rotation
Button adjusting section pressure size, to adjust SPE column flow rate of liquid.In the whole process, can switch as needed pressure switching valve to 0~
30 psi flow paths or 0~160 psi flow paths.
The utility model solves positive-pressure solid-phase extracting device and solvent need to frequently be added and cannot be applicable in 1 mL SPE columns
Problem is applicable to the cylinder of different size, 50 mL solvents can once be added, and can once handle 36 samples simultaneously, letter
Change operating process, realizes the Precise control of column flow rate, entire solid phase extraction procedure is quickly, efficiently.
Description of the drawings
Fig. 1 is the structural schematic diagram of the utility model.
In Fig. 1：1 is lifting bracket switch, and 2 be 0~30 psi pressure adjustment knobs, and 3 be 0~30 psi pressure gauges, and 4 be pressure
Power switching valve, 5 be 0~160 psi pressure gauges, and 6 be 0~160 psi pressure adjustment knobs, and 7 be Solid Phase Extraction cell pressure
Switching valve, 8 be device panel, and 9 be crane, and 10 be Solid Phase Extraction component.
Fig. 2 is lessivation extraction equipment schematic diagram.
Fig. 3 is elution process extraction equipment schematic diagram.
Fig. 4 is Solid Phase Extraction component diagram, and 10-1 is glass tube, and 10-2 is adapter, and 10-3 is SPE columns；
Fig. 5 is conversion head front view and vertical view in Fig. 4.
Fig. 6 is the principles of the present invention figure, and 11 be the gas circuit jack on device panel, other label title such as Fig. 1.
Specific implementation mode
The utility model is described further below in conjunction with attached drawing：
As shown in the figure：A kind of high throughput positive-pressure solid-phase extracting device, including pressure source, rack, device panel 8, pressure tune
Save unit, Solid Phase Extraction unit, the gas circuit being connected between Unit two and the multiple gas circuit jacks being arranged on device panel 8
11；The Solid Phase Extraction unit is arranged in rack on set crane 9, and Solid Phase Extraction unit includes multiple arranged side by side
Solid Phase Extraction component 10, each Solid Phase Extraction component is by vial 10-1 mating successively, adapter 10-2 and SPE column
10-3 is constituted；The pressure regulating unit includes being divided for branch's gas of two-way different pressures adjustable range by pressure switching valve 4
Road, pressure adjustment knob（2、6）, pressure gauge（3、5）And the gas path on-off switching valve 7 being connected with Solid Phase Extraction unit；Gu
The company of entire gas circuit is realized by the gas circuit jack 11 on docking facilities panel 8 in the upper ends vial 10-1 in phase extraction module 10
It is logical.
The Solid Phase Extraction unit can be 3 groups, and every group includes 12 Solid Phase Extraction components 10；Every group of Solid Phase Extraction unit is equal
It is connected with pressure regulating unit by gas path on-off switching valve 7.
Device panel（Panel lower face）8 are equipped with three exhaust line jacks 11, often arrange 12, can extract simultaneously with three groups of solid phases
It takes the total 36 Solid Phase Extraction components of unit to be connected and carries out extracting operation.
Two-way different pressures adjustable range is respectively 0~30 psi and 0~160 psi.
Pressure source is compressed air or nitrogen cylinder.
The SPE columns can be the cylinder of different size, include the cylinder of 1~6 mL.
The pressure switching valve 4, pressure adjustment knob（2、6）, pressure gauge（3、5）, gas path on-off switching valve 7 is arranged at
On device panel 8.
In use, glass tube 10-1 wants the gas circuit jack 11 on alignment device panel 8, switching valve 7 is pulled, Solid Phase Extraction is made
Unit is connect with gas circuit, pulls pressure switching valve 4, makes pressure adjustment knob 2 and corresponding pressure gauge 3 or pressure adjustment knob 6
And corresponding pressure gauge 5 is connected to gas circuit, rotational pressure adjusting knob 2 or 6 is to adjust SPE column flow rate of liquid.According to experiment
Demand selects lessivation Solid Phase Extraction cell arrangement（Referring to Fig. 2）Or elution process Solid Phase Extraction cell arrangement（Referring to Fig. 3）.
Below by embodiment to using process to further illustrate：
Example 1：
Polycyclic aromatic hydrocarbon in the main flume of 36 cigarette is analyzed using Solid Phase Extraction pretreatment technology, SPE columns are C18Column 3
Glass tube is connect by mL using crossover sub with SPE columns, is packed into lessivation Solid Phase Extraction cell arrangement, and 10 mL methanol are added
In glass tube, glass tube is aligned solvent with gas circuit hole 11, pulls Solid Phase Extraction cell pressure switching valve 7, pulls pressure switching
Valve 4 makes pressure adjustment knob 2 be connected to gas circuit, and adjusting pressure is 10 psi, C18Column flow rate is about 1 drop/sec, is waited in glass tube
It when solvent is remaining seldom, pulls at pressure switching valve 4 to off, 10 mL of sample solution is added, repeat above procedure, elution is added
30 mL of solvent methanol water repeats above procedure；Elution process Solid Phase Extraction cell arrangement is replaced, by C18Column and connection glass tube
It moves in device, 30 mL cyclohexane solvents is added, pulls pressure switching valve 4, pressure adjustment knob 6 is made to be connected to gas circuit, adjust
Pressure is that 40 psi pull pressure switching valve 4 to off, pull Solid Phase Extraction after cyclohexane solvent all flows out to receiving flask
Cell pressure switching valve 7 is to off.Whole operation is no more than 30 minutes, easy to operate, efficient, and can once handle 36 samples,
Suitable batch samples are quickly handled.
Claims (7)
1. a kind of high throughput positive-pressure solid-phase extracting device, it is characterised in that：It is adjusted including pressure source, rack, device panel, pressure
Unit, Solid Phase Extraction unit, the gas circuit being connected between Unit two and the multiple gas circuit jacks being arranged on device panel；It is described
Solid Phase Extraction unit is arranged in rack on set crane, and Solid Phase Extraction unit includes multiple Solid Phase Extraction arranged side by side
Component, each Solid Phase Extraction component are made of vial mating successively, adapter and SPE columns；The pressure is adjusted
Unit includes branch air path, pressure adjustment knob, the pressure gauge for being divided into two-way different pressures adjustable range by pressure switching valve
And the gas path on-off switching valve being connected with Solid Phase Extraction unit；Vial upper end in Solid Phase Extraction component passes through to tipping
Set the connection that the gas circuit jack on panel realizes entire gas circuit.
2. high throughput positive-pressure solid-phase extracting device according to claim 1, it is characterised in that：The Solid Phase Extraction unit can
To be multigroup, every group includes 12 Solid Phase Extraction components；Every group of Solid Phase Extraction unit passes through gas path on-off switching valve and pressure tune
Section unit is connected.
3. high throughput positive-pressure solid-phase extracting device according to claim 1, it is characterised in that：Device panel is equipped with three rows
Gas circuit jack often arranges 12, can amount to the progress extracting operation that is connected with three groups of Solid Phase Extraction units simultaneously.
4. high throughput positive-pressure solid-phase extracting device according to claim 1, it is characterised in that：Two-way different pressures adjust model
Enclose respectively 0~30 psi and 0~160 psi.
5. high throughput positive-pressure solid-phase extracting device according to claim 1, it is characterised in that：Pressure source be compressed air or
Nitrogen cylinder.
6. high throughput positive-pressure solid-phase extracting device according to claim 1, it is characterised in that：The SPE columns can be difference
The cylinder of specification includes the cylinder of 1~6 mL.
7. high throughput positive-pressure solid-phase extracting device according to claim 1, it is characterised in that：The pressure switching valve, pressure
Power adjusting knob, pressure gauge, gas path on-off switching valve are arranged on device panel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721559387.XU CN207614406U (en) | 2017-11-21 | 2017-11-21 | A kind of high throughput positive-pressure solid-phase extracting device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721559387.XU CN207614406U (en) | 2017-11-21 | 2017-11-21 | A kind of high throughput positive-pressure solid-phase extracting device |
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| Publication Number | Publication Date |
|---|---|
| CN207614406U true CN207614406U (en) | 2018-07-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201721559387.XU Active CN207614406U (en) | 2017-11-21 | 2017-11-21 | A kind of high throughput positive-pressure solid-phase extracting device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109806618A (en) * | 2019-04-03 | 2019-05-28 | 四川轻化工大学 | Integrated adjustable multi-channel solid phase extraction device and use method thereof |
| CN110596285A (en) * | 2019-08-29 | 2019-12-20 | 重庆同怡生物技术研究院有限公司 | High-flux positive-pressure gas distribution device |
-
2017
- 2017-11-21 CN CN201721559387.XU patent/CN207614406U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109806618A (en) * | 2019-04-03 | 2019-05-28 | 四川轻化工大学 | Integrated adjustable multi-channel solid phase extraction device and use method thereof |
| CN109806618B (en) * | 2019-04-03 | 2021-06-29 | 四川轻化工大学 | Integrated adjustable multi-channel solid phase extraction device and use method thereof |
| CN110596285A (en) * | 2019-08-29 | 2019-12-20 | 重庆同怡生物技术研究院有限公司 | High-flux positive-pressure gas distribution device |
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