CN207330807U - A kind of quick preparation device of monoclonal antibody - Google Patents
A kind of quick preparation device of monoclonal antibody Download PDFInfo
- Publication number
- CN207330807U CN207330807U CN201721341028.7U CN201721341028U CN207330807U CN 207330807 U CN207330807 U CN 207330807U CN 201721341028 U CN201721341028 U CN 201721341028U CN 207330807 U CN207330807 U CN 207330807U
- Authority
- CN
- China
- Prior art keywords
- pipe
- monoclonal antibody
- band
- constant incubator
- storage bin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a kind of quick preparation device of monoclonal antibody, including equipment body and constant incubator, equipment body is made of band pipe storage bin and culture plate, and constant incubator is placed on culture plate and cultivates, and be connected by delivery pipe with pipe storage bin, it is convenient to convey nutriment；Side cover is provided with band pipe storage bin, is conveniently replaceable and adds storage thing；Constant temperature incubation box top is correspondingly arranged on band channel cover, and band channel cover is connected with abdominal cavity film, and abdominal cavity film is fixed on constant incubator bottom by fixed frame, crosses whole constant incubator, mimic biology abdominal cavity environment；The utility model is by abdominal cavity film mimic biology abdominal cavity environment, so that the success rate of monoclonal antibody preparation is improved, and culture plate realizes scale prepared by monoclonal antibody.
Description
Technical field
Antibody preparation device field is the utility model is related to, is specially a kind of quick preparation device of monoclonal antibody.
Background technology
Monoclonal antibody technique is the important process of modern life science research, in gene and the 26S Proteasome Structure and Function of protein
Play the role of in terms of research indispensable.
Monoclonal antibody possesses internal with external two kinds of preparation methods, i.e., the method and body of production monoclonal antibody in animal body at present
The method of outer culture production monoclonal antibody；The method of production monoclonal antibody, easy to operate, economic but organism are interior containing various in animal body
Foreign protein, therefore could be used after purifying under many circumstances, and also have the danger for polluting animal virus, and existing body
Monoclonal antibody amount prepared by the method for outer culture production monoclonal antibody is extremely limited, and is not suitable for the large-scale production of monoclonal antibody.
The content of the invention
The technical problems to be solved in the utility model is to overcome existing preparation monoclonal antibody easy to pollute, difficult purification and scale
The defects of small, there is provided a kind of quick preparation device of monoclonal antibody, so as to solve the above problems.
In order to solve the above-mentioned technical problem, the utility model provides following technical solution：
A kind of quick preparation device of monoclonal antibody, including equipment body and constant incubator, equipment body are managed by band
Storage bin and culture plate composition, constant incubator are placed in the culture tank on culture plate, and by delivery pipe with being stored with pipe
Case connects；Side cover is provided with band pipe storage bin, cover lock is installed, cover lock passes through Snap close connecting band pipe storage bin on side cover；It is permanent
Band channel cover is correspondingly arranged at the top of warm incubator, with sealing ring is provided with around channel cover, sealing ring passes through band channel cover
Parcel abdominal cavity film is fixedly connected with constant incubator, and abdominal cavity film is fixed on the bottom of constant incubator by fixed frame, and covering is whole
Constant incubator.
As a kind of optimal technical scheme of the utility model, with channel cover with being both provided with pipe at the top of pipe storage bin
Plug, and the side of pipe close is fixedly connected with corresponding top.
As a kind of optimal technical scheme of the utility model, water pump is installed in the delivery pipe.
As a kind of optimal technical scheme of the utility model, the delivery pipe both ends are connected respectively by screw thread movable sleeve
Defeated foster pipe on constant incubator and with the antipriming pipe on pipe storage bin.
As a kind of optimal technical scheme of the utility model, the porous bottom of the tube, which is provided with, can connect some pipes
Connecting hole.
As a kind of optimal technical scheme of the utility model, the abdominal cavity film is a kind of tunica fibrosa.
The beneficial effect that the utility model is reached is：Trained by the constant incubator and connection constant temperature that are provided with abdominal cavity film
Case and the delivery pipe with pipe storage bin are supported, mimic biology abdominal cavity environment, conveys nutriment so that success rate prepared by monoclonal antibody
Greatly improve；Be conducive to culture device with the pipe close and sealing ring set on channel cover and with the pipe close set on pipe storage bin
With the management and control of storage facilities health, hygienic conditions good in experiment are maintained；Some culture tanks are fixedly mounted on culture plate to realize
Scale prepared by monoclonal antibody；Side door lid is provided with band channel cover so that.
Brief description of the drawings
Attached drawing is used to provide a further understanding of the present invention, and a part for constitution instruction, with this practicality
New embodiment is used to explain the utility model together, does not form the limitation to the utility model.
In the accompanying drawings：
Fig. 1 is the utility model structure diagram；
Fig. 2 is the utility model constant incubator explosive view；
Fig. 3 is the utility model pipe structure schematic diagram；
Fig. 4 be the utility model antipriming pipe with pipe storage bin connection figure
Figure label：1st, apparatus body；2nd, constant incubator；3rd, band pipe storage bin；4th, culture plate；5th, abdominal cavity film；6th, band
Channel cover；7th, sealing ring；8th, defeated foster pipe；9th, pipe close；10th, fixed frame；11st, side cover；12nd, cover lock；13rd, latch；14th, antipriming pipe；
15th, culture tank；16 screw thread movable sleeves；17th, delivery pipe；18th, water pump.
Embodiment
The preferred embodiment of the utility model is illustrated below in conjunction with attached drawing, it will be appreciated that described herein excellent
Select embodiment to be only used for describing and explaining the present invention, be not used to limit the utility model.
, it is necessary to explanation in the description of the utility model, the instruction such as term " vertical ", " on ", " under ", " level "
Orientation or position relationship are based on orientation shown in the drawings or position relationship, are for only for ease of description the utility model and letter
Change description, rather than instruction or imply signified device or element must have specific orientation, with specific azimuth configuration and
Operation, therefore it is not intended that limitation to the utility model.
In the description of the utility model, it is also necessary to which explanation, unless otherwise clearly defined and limited, term " are set
Put ", " installation ", " connected ", " connection " should be interpreted broadly, for example, it may be fixedly connected or be detachably connected,
Or it is integrally connected；Can mechanically connect or be electrically connected；It can be directly connected, intermediary can also be passed through
It is indirectly connected, can is the connection inside two elements.For the ordinary skill in the art, can be according to specific
Situation understands concrete meaning of the above-mentioned term in the utility model.
Embodiment：As shown in Figs 1-4, the utility model provides a kind of quick preparation device of monoclonal antibody, including sets
Standby main body 1 and constant incubator 2, equipment body 1 are made of band pipe storage bin 3 and culture plate 4, and the culture to monoclonal antibody carries
Place for preparing storage nutrition；Constant incubator 2 is placed in the culture tank 15 on culture plate 4, and by delivery pipe 17 with
Band pipe storage bin 3 connects, and some culture tanks 15 are fixed with culture plate 4, can cultivate the monoclonal antibody of some batches at the same time,
Realize mass, the scale of monoclonal antibody preparation, nutriment in band pipe storage bin 3 is transported to constant temperature and trained by delivery pipe 17
Support in case 2 so that monoclonal antibody has the nutriment and effect gas of abundance in incubation；Set on band pipe storage bin 3
Side cover 11 is equipped with, cover lock 12 is installed on side cover 11, cover lock is by latching 13 connect band pipe storage bins 3, when needing to add nutrition
During material, side cover 11 can be opened, is conveyed by delivery pipe 17, avoids adding the pollution problem being likely to result in manually；Constant temperature is trained
Support the top of case 2 and be correspondingly arranged on band channel cover 6, with sealing ring 7 is provided with around channel cover 6, sealing ring 7 passes through band channel cover
6 parcel abdominal cavity films 5 are fixedly connected with constant incubator, can completely cut off the influence that external environment prepares monoclonal antibody, abdominal cavity film 5
The bottom of constant incubator 2 is fixed on by fixed frame 10, covers whole constant incubator 2, produced in vitro monoclonal is completed and resists
For body culture environment as abdominal cavity environment in organism, raising is prepared into power.
Be both provided with pipe close 9 with channel cover 6 and the top with pipe storage bin 3, and the side of pipe close 9 with corresponding top
It is fixedly connected, pipe close 9 can clog the pore of antipriming pipe 14 and defeated foster pipe 8 when equipment stops operating, and prevent pollutant from entering
In pipe, apparatus sanitation is kept.
Water pump 18 is installed, water pump 18 passes through the action draws nutrient solution and effect gas of power, water in the delivery pipe 17
Pump realizes automation, avoids culture environment caused by adding nutrients manually from polluting by the action draws nutriment of power.
The delivery pipe 17 is provided at both ends with screw thread movable sleeve 16 so that the both ends of delivery pipe 17 connection antipriming pipe 14 and defeated
It can write when supporting pipe 8 tight, at sealed connection, hinder pollutant to enter pipeline.
The antipriming pipe 14 sets bottom to have some connecting holes, can connect some pipes at the same time, work as monoclonal antibody
When required nutriment is a variety of, different pipes can be installed on several connecting holes of antipriming pipe 14, be passed through by water pump 18
Delivery pipe 17 is transported in constant incubator 2.
The abdominal cavity film 5 is a kind of tunica fibrosa, with good heatproof, acid and alkali-resistance and oxidation resistent susceptibility, and it is fine and close
Property is very good, particulate, bacterium and other small items that can be in trap water.
Operation principle：Using a kind of quick preparation device of monoclonal antibody of the utility model, first, by abdominal cavity film 5
The inside of constant incubator 2 is installed on by fixed frame 10, the constant incubator 2 for being provided with abdominal cavity film 5 is placed on culture plate 4
Culture tank 15 in cultivate, complete produced in vitro monoclonal antibody culture environment as abdominal cavity environment in organism；Secondly, rotation
Turning screw thread movable sleeve 16 makes the both ends of delivery pipe 17 install defeated foster pipe 8 and antipriming pipe 14 respectively, so as to connect constant incubator 2
With band pipe storage tank 3, water pump 18 is opened, constant incubator 2 will be transported to the nutriment in pipe storage tank 3 and effect gas
In so that monoclonal antibody has the nutriment and effect gas of abundance in incubation；Finally, when in band pipe storage tank 3
Nutriment and effect gas it is inadequate when, required article is added by locking closure 12 and the opening side covers 11 of lock 13.
Finally it should be noted that：It these are only the preferred embodiment of the utility model, be not limited to this practicality
It is new, although the utility model is described in detail with reference to the foregoing embodiments, for those skilled in the art,
It can still modify the technical solution described in foregoing embodiments, or which part technical characteristic is carried out etc.
With replacement.Where within the spirit and principles of the present invention, any modification, equivalent replacement, improvement and so on, should all include
Within the scope of protection of the utility model.
Claims (6)
1. a kind of quick preparation device of monoclonal antibody, it is characterised in that including equipment body（1）And constant incubator（2）,
Equipment body（1）By band pipe storage bin（3）And culture plate（4）Composition, constant incubator（2）It is placed on culture plate（4）On training
Support groove（15）In, constant incubator（2）Pass through delivery pipe（17）Connect band pipe storage bin（3）；Band pipe storage bin（3) it is provided with
Side cover (11), side cover（11）On cover lock is installed（12）, cover lock（12）Pass through lock（13）Connect band pipe storage bin（3）；Constant temperature
Incubator（2）Top is correspondingly arranged on band channel cover（6）, band channel cover（6）Around sealing ring is installed（7）, sealing ring（7）
Pass through band channel cover（6）Wrap up abdominal cavity film（5）It is fixedly connected with constant incubator（2）, abdominal cavity film（5）Pass through fixed frame（10）It is fixed
In constant incubator（2）Bottom, cover whole constant incubator（2）.
A kind of 2. quick preparation device of monoclonal antibody according to claim 1, it is characterised in that band channel cover（6）
With band pipe storage bin（3）Top be both provided with pipe close（9）, and pipe close（9）Side be fixedly connected with corresponding top.
A kind of 3. quick preparation device of monoclonal antibody according to claim 1, it is characterised in that the delivery pipe
（17）On water pump is installed（18）.
A kind of 4. quick preparation device of monoclonal antibody according to claim 1, it is characterised in that the delivery pipe
（17）Both ends pass through screw thread movable sleeve（16）Constant incubator is connected respectively（2）On defeated foster pipe（8）With band pipe storage bin（3）On
Antipriming pipe（14）.
A kind of 5. quick preparation device of monoclonal antibody according to claim 4, it is characterised in that antipriming pipe（14）Bottom
Portion is provided with the connecting hole that can connect some pipes.
A kind of 6. quick preparation device of monoclonal antibody according to claim 1, it is characterised in that the abdominal cavity film
（5）It is a kind of tunica fibrosa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721341028.7U CN207330807U (en) | 2017-10-18 | 2017-10-18 | A kind of quick preparation device of monoclonal antibody |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721341028.7U CN207330807U (en) | 2017-10-18 | 2017-10-18 | A kind of quick preparation device of monoclonal antibody |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207330807U true CN207330807U (en) | 2018-05-08 |
Family
ID=62365490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721341028.7U Active CN207330807U (en) | 2017-10-18 | 2017-10-18 | A kind of quick preparation device of monoclonal antibody |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207330807U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111304082A (en) * | 2020-03-06 | 2020-06-19 | 通用生物系统（安徽）有限公司 | Biological antibody culture device and culture method |
-
2017
- 2017-10-18 CN CN201721341028.7U patent/CN207330807U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111304082A (en) * | 2020-03-06 | 2020-06-19 | 通用生物系统（安徽）有限公司 | Biological antibody culture device and culture method |
| CN111304082B (en) * | 2020-03-06 | 2021-04-20 | 通用生物系统（安徽）有限公司 | Biological antibody culture device and culture method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0938544B1 (en) | Cell/tissue culturing device and method | |
| US6709862B2 (en) | Growing cells in a reservoir formed of a flexible sterile plastic liner | |
| CN106520552B (en) | A kind of biological reactor for cell culture | |
| WO2019214465A1 (en) | Fluidized bed cell culture disposable membrane device filled with flaky carriers | |
| CN102220242A (en) | Culture solution continuous filling method and system for chlamydomonas culture | |
| CN103224882B (en) | Disposable wave type bioreactor with aerating apparatus | |
| CN207330807U (en) | A kind of quick preparation device of monoclonal antibody | |
| CN110092535B (en) | Integrated reactor and process for biogas slurry nitrogen and phosphorus recovery and biomass production | |
| CN204939455U (en) | A kind of Novel anaerobic culture tank | |
| CN208857315U (en) | A kind of plant cell and organ Liquid Culture bag | |
| CN204251599U (en) | A kind of anaerobic microorganism culturing device | |
| JP5721382B2 (en) | Microorganism culture system and microorganism culture method | |
| CN210496472U (en) | Experimental device for be used for soil cultivation | |
| CN217438205U (en) | Dual-environment co-culture plate | |
| CN208087626U (en) | A kind of fast and efficiently anaerobic bacteria culture easy device | |
| CN108424855A (en) | A kind of plant cell, organ liquid culturing apparatus | |
| CN214060509U (en) | Liquid strain culture tank for needle mushrooms | |
| CN201420080Y (en) | Sealed microalgae industry photosynthesis cultivating device | |
| CN207330958U (en) | A kind of three-in-one bioreactor | |
| CN206545025U (en) | Liquid strain culturing device and liquid bacterial strain production system | |
| CN208857314U (en) | A kind of plant cell, organ liquid culturing apparatus | |
| CN208250338U (en) | A kind of Bacteria Culture device assembly | |
| CN206599569U (en) | A kind of reactor for dry anaerobic fermentation | |
| CN108441425A (en) | A kind of plant cell, organ culture device | |
| CN211620532U (en) | CO with good sealing performance2Culture box |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |