CN207067107U - Detect the device of medicine disintegration degree - Google Patents

Detect the device of medicine disintegration degree Download PDF

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Publication number
CN207067107U
CN207067107U CN201720984529.0U CN201720984529U CN207067107U CN 207067107 U CN207067107 U CN 207067107U CN 201720984529 U CN201720984529 U CN 201720984529U CN 207067107 U CN207067107 U CN 207067107U
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China
Prior art keywords
disintegration
elastic construction
capsule
gas passage
entrance
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CN201720984529.0U
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Chinese (zh)
Inventor
刘宏伟
黄渊帅
肖玥
谢显珍
熊峻
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Changde Vocational Technical College
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Changde Vocational Technical College
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Abstract

It the utility model is related to medicine detection instrument field, disclose a kind of device for detecting medicine disintegration degree, including disintegration case (1), disintegration capsule (2) is provided with the disintegration case (1), contain gas passage (3) in the disintegration capsule (2), at least two elastic constructions (4) are provided between the both ends of the gas passage (3);Entrance (5) and outlet (6) are provided with the disintegration capsule (2), the both ends of the gas passage (3) are each passed through entrance (5) and the outlet (6) of the disintegration capsule (2);The entrance (5) is used to introduce liquid medium and medicine into the disintegration capsule (2);The outlet is flexibly connected with the outer wall of the gas passage (3) run through.Device of the present utility model can simulate stomach and wriggle to drive the actual disintegration environment that medicine moves.

Description

Detect the device of medicine disintegration degree
Technical field
Medicine detection instrument field is the utility model is related to, in particular it relates to a kind of device for detecting medicine disintegration degree.
Background technology
Disintegration tester is basis《Pharmacopoeia of People's Republic of China》Ground about the regulation that the disintegration time limiteds such as tablet, pill are detected The medicine inspection instrument of system, sets multiple beakers, holding medicine in beaker, is moved up and down beaker by elevating mechanism, observes medicine Disintegration situation to detect the disintegration time limited of medicine.
Because medicine is typically in disintegration in the stomach, and prior art provides is only through the moving up and down to drive of beaker The movement of medicine can not simulate stomach wriggling to drive the environment of the actual disintegration of medicine movement come the disintegration tester tested, from And cause using the disintegration tester of prior art offer come testing drug disintegration when the result that obtains do not have too many reality Meaning.
Utility model content
The purpose of this utility model is the defects of overcoming prior art, there is provided one kind can simulate stomach and wriggle to drive medicine The device of the testing drug disintegration of the actual disintegration environment of thing movement.
In order to solve the above-mentioned technical problem, the utility model provides a kind of device for detecting medicine disintegration degree, the device Including being disintegrated case, disintegration capsule is provided with the disintegration case, gas passage, the both ends of the gas passage are contained in the disintegration capsule Between be provided with least two elastic constructions;Entrance and exit, the both ends point of the gas passage are provided with the disintegration capsule Chuan Guo not the entrance and exit that capsule is disintegrated;The entrance is used to introduce liquid medium and medicine into the disintegration capsule;Institute Outlet is stated to be flexibly connected with the outer wall of the gas passage run through.
In the disintegration of testing drug, the liquid medium of the disintegration for testing drug is contained in the disintegration capsule, In order to prevent the liquid medium from being flowed out by the outlet, the outlet is set to off closed state.That is, the outlet is enclosed It is closed around the gas passage.
After being completed, the outlet of the disintegration capsule can be opened, is drawn the liquid medium with facilitating.
According to the first preferred embodiment, the first elastic construction and the second elasticity are contained in the elastic construction Structure, and the scalability of first elastic construction and the second elastic construction is different.
It is described on the basis of the first preferred embodiment according to second of preferred embodiment In elastic construction also containing the 3rd elastic construction or and the 4th elastic construction, and the scalability of two neighboring elastic construction It is different.
The elastic construction of the present utility model can also set more than 4.Under preferable case, each elastic construction 1.2~20 times of length of inelastic structural component of the length between two neighboring elastic construction.
It is preferred that the inelastic structural component of the gas passage does not have retractility.
Under preferable case, the close arrival end of the gas passage is connected with the source of the gas with pressure so that is come from The gas with pressure of the source of the gas enters the gas passage, and sequentially passes through at least two elastic construction.It is excellent In the case of choosing, the air pressure into the gas with pressure in the gas passage is over time and different.People in the art Member can set the air pressure of (regulation) gas according to the wriggling situation of stomach, so that the elastic construction is at different moments Flexible situation is different.Also, the utility model discontinuous by the way of the peristole cycle is simulated introduces the gas.
The utility model has no particular limits to the material of the elastic construction, if can realize elastic construction with The introducing of pressed gas and carry out flexible.
The gas that the utility model carries pressure by being introduced into enters in the gas passage with elastic construction so that gas Irregularly stretching occurs in elastic construction in passage, so as to correspondingly cause the motion for being disintegrated intracapsular liquid medium, this fortune The dynamic actual environment that can be substantially more nearly stomach.
Preferably, the disintegration capsule is spheroid shape, and the close arrival end of the disintegration capsule is in the disintegration case Height than close to the port of export height it is high.
Preferably, visual windows are provided with the disintegration capsule, and the disintegration capsule in addition to visual windows part in Portion is provided with irregular raised structures.The disintegration situation of the medicine in the disintegration capsule can be observed by the visual windows. The raised structures are preferably transparence, and the raised structures can simulate stomach interior wall construction.
Under preferable case, the utricule part of the disintegration capsule is made up of transparent material.It is preferred that the utricule portion of the disintegration capsule The elasticity divided is significantly less than the elasticity of the elastic construction of the gas passage.Or the disintegration capsule can not have elasticity.
Using it is provided by the utility model detection medicine disintegration degree device when, preferred embodiment is:Close disintegration The outlet of capsule, from it is described disintegration capsule entrance introduce liquid medium (liquid medium for simulation stomach inner case liquid) and Medicine, the gas with pressure is introduced from the nearly arrival end of the gas passage with certain cycle (simulation peristole cycle), The gas of introducing passes sequentially through each elastic construction;Also, because the scalability of each elastic construction is different so that gas leads to Disintegration capsule is caused to produce " wriggling " of different amplitudes when crossing elastic construction.
Device of the present utility model causes medicine disintegration environment closer to the actual environment wriggled in stomach, so as to improve disintegration The measure accuracy of degree, this has great importance for medicament and Pharmaceutical Analysis field.
Brief description of the drawings
Fig. 1 is a kind of structural representation of the disintegration tester of preferred embodiment of the present utility model;
Fig. 2 is a kind of structural representation of the disintegration capsule of preferred embodiment of the present utility model.
Description of reference numerals
1st, it is disintegrated case 2, disintegration capsule
3rd, gas passage 4, elastic construction
41st, the first elastic construction 42, the second elastic construction
43rd, the 3rd elastic construction
5th, entrance 6, outlet
7th, visual windows 8, raised structures
Embodiment
The end points of disclosed scope and any value are not limited to the accurate scope or value herein, these scopes or Value should be understood to comprising the value close to these scopes or value.For number range, between the endpoint value of each scope, respectively It can be combined with each other between the endpoint value of individual scope and single point value, and individually between point value and obtain one or more New number range, these number ranges should be considered as specific open herein.
The device of testing drug disintegration of the present utility model is described in detail below in conjunction with accompanying drawing.
As shown in figure 1, the device of testing drug disintegration of the present utility model includes:The device includes disintegration case 1, described Disintegration capsule 2 is provided with disintegration case 1, contains gas passage 3 in the disintegration capsule 2, is provided between the both ends of the gas passage 3 At least two elastic constructions 4;Entrance 5 and outlet 6 are provided with the disintegration capsule 2, the both ends of the gas passage 3 are each passed through The entrance 5 of the disintegration capsule 2 and outlet 6;The entrance 5 is used to introduce liquid medium and medicine into the disintegration capsule 2;It is described Export and be flexibly connected with the outer wall of the gas passage 3 run through.
In the disintegration of testing drug, the liquid medium of the disintegration for testing drug is contained in the disintegration capsule 2, In order to prevent the liquid medium that by the outflow of outlet 6, the outlet 6 is set to off into closed state.That is, the outlet 6 is closed around the gas passage 3.
After being completed, the outlet of the disintegration capsule 2 can be opened, is drawn the liquid medium with facilitating.
According to the first preferred embodiment, the first elastic construction 41 and second is contained in the elastic construction 4 Elastic construction 42, and first elastic construction 41 is different with the scalability of the second elastic construction 42.
It is described on the basis of the first preferred embodiment according to second of preferred embodiment In elastic construction also containing the 3rd elastic construction 43 or and the 4th elastic construction, and two elastic constructions of arbitrary neighborhood can Retractility is different.
The elastic construction of the present utility model can also set more than 4.Under preferable case, each elastic construction 1.2~20 times of the length of inelastic structural component of 4 length between two neighboring elastic construction.Thus, it is possible to more stick on " wriggling " situation is cut in simulation stomach.
It is preferred that the inelastic structural component of the gas passage 3 does not have retractility.
Under preferable case, the close arrival end of the gas passage 3 is connected with the source of the gas with pressure so that is come from The gas with pressure of the source of the gas enters the gas passage 3, and sequentially passes through at least two elastic construction 4. Under preferable case, the air pressure into the gas with pressure in the gas passage 3 is over time and different.Art technology Personnel can set the air pressure of (regulation) gas according to the wriggling situation of stomach, so that the elastic construction 4 is when different The flexible situation carved is different.Also, the utility model discontinuous by the way of the peristole cycle is simulated introduces the gas.
The utility model has no particular limits to the material of the elastic construction 4, if can realize elastic construction 4 with The introducing of pressed gas and carry out flexible.
The gas that the utility model carries pressure by being introduced into enters in the gas passage 3 with elastic construction 4 so that gas Irregularly stretching occurs in elastic construction 4 in body passage 3, so as to correspondingly cause the motion of the liquid medium in disintegration capsule 2, this Kind motion can substantially be more nearly the actual environment of stomach.
Preferably, the disintegration capsule 2 is spheroid shape, and the close arrival end of the disintegration capsule 2 is in the disintegration case 1 In height than close to the port of export height it is high.
Preferably, visual windows 7 are provided with the disintegration capsule 2, and the disintegration capsule 2 is in addition to the part of visual windows 7 Be internally provided with irregular raised structures 8 (as shown in Fig. 2 of the present utility model).It can be seen by the visual windows 7 Examine the disintegration situation of the medicine in the disintegration capsule 2.The raised structures 8 preferably transparence, and the energy of the raised structures 8 Enough simulate stomach interior wall construction.
Under preferable case, the utricule part of the disintegration capsule 2 is made up of transparent material.It is preferred that the utricule of the disintegration capsule 2 Partial elasticity is significantly less than the elasticity of the elastic construction 4 of the gas passage 3.Or the disintegration capsule 2 can not have bullet Property.
Using it is provided by the utility model detection medicine disintegration degree device when, preferred embodiment is:Close disintegration The outlet 6 of capsule 2, the liquid medium (liquid of inner case of the liquid medium for simulation stomach is introduced from the entrance 5 of the disintegration capsule 2 Body) and medicine, introduced with certain cycle (simulation peristole cycle) from the nearly arrival end of the gas passage 3 with pressure Gas, the gas of introducing pass sequentially through each elastic construction 4;Also, because the scalability of each elastic construction 4 is different, make Obtain " wriggling " for causing disintegration capsule 2 to produce different amplitudes when gas passes through elastic construction.
Preferred embodiment of the present utility model described in detail above, still, the utility model is not limited to this.At this In the range of the technology design of utility model, a variety of simple variants can be carried out to the technical solution of the utility model, including it is each Technical characteristic is combined with any other suitable method, and these simple variants and combination should equally be considered as the utility model Disclosure of that, belong to the scope of protection of the utility model.

Claims (7)

  1. A kind of 1. device for detecting medicine disintegration degree, it is characterised in that:The device includes disintegration case (1), described to be disintegrated in case (1) Disintegration capsule (2) is provided with, contains gas passage (3) in the disintegration capsule (2), is provided between the both ends of the gas passage (3) At least two elastic constructions (4);Entrance (5) is provided with the disintegration capsule (2) and exports (6), the two of the gas passage (3) End is each passed through entrance (5) and the outlet (6) of the disintegration capsule (2);The entrance (5) is used into the disintegration capsule (2) draw Enter liquid medium and medicine;The outlet is flexibly connected with the outer wall of the gas passage (3) run through.
  2. 2. device according to claim 1, it is characterised in that:Contain the first elastic construction in the elastic construction (4) (41) and the second elastic construction (42), and the scalability of first elastic construction (41) and the second elastic construction (42) is not Together.
  3. 3. device according to claim 1, it is characterised in that:Also contain the 3rd elastic construction in the elastic construction (4) (43) or and the 4th elastic construction, and the scalability of two neighboring elastic construction is different.
  4. 4. according to the device described in any one in claim 1-3, it is characterised in that:The close institute of the gas passage (3) State entrance (5) end to be connected with the source of the gas with pressure so that the gas with pressure from the source of the gas enters the gas Passage (3), and sequentially pass through at least two elastic construction (4).
  5. 5. device according to claim 4, it is characterised in that:The disintegration capsule (2) is spheroid shape, and the disintegration capsule (2) height ratio height close to outlet (6) end of close entrance (5) end in the disintegration case (1) is high.
  6. 6. device according to claim 4, it is characterised in that:Visual windows (7) are provided with the disintegration capsule (2), and The disintegration capsule (2) is internally provided with irregular raised structures (8) in addition to visual windows (7) part.
  7. 7. device according to claim 4, it is characterised in that:The length of each elastic construction (4) is two neighboring 1.2~20 times of the length of inelastic structural component between elastic construction (4).
CN201720984529.0U 2017-08-08 2017-08-08 Detect the device of medicine disintegration degree Active CN207067107U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201720984529.0U CN207067107U (en) 2017-08-08 2017-08-08 Detect the device of medicine disintegration degree

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201720984529.0U CN207067107U (en) 2017-08-08 2017-08-08 Detect the device of medicine disintegration degree

Publications (1)

Publication Number Publication Date
CN207067107U true CN207067107U (en) 2018-03-02

Family

ID=61520131

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201720984529.0U Active CN207067107U (en) 2017-08-08 2017-08-08 Detect the device of medicine disintegration degree

Country Status (1)

Country Link
CN (1) CN207067107U (en)

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