CN207007863U - Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector - Google Patents
Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector Download PDFInfo
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- CN207007863U CN207007863U CN201720941969.8U CN201720941969U CN207007863U CN 207007863 U CN207007863 U CN 207007863U CN 201720941969 U CN201720941969 U CN 201720941969U CN 207007863 U CN207007863 U CN 207007863U
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Abstract
Medical experiment equipment is the utility model is related to, is cross matching and ABO and RhD blood groups and irregular antibody examination sample injector, it has a distribution pipe closed at both ends, it is characterized in that：At least one syringe is arranged side by side with distribution pipe, syringe needle position is located at distribution pipe lower end through distribution pipe, position on syringe in distribution pipe is provided with radial direction through hole, and being provided with a sample-adding side by side with syringe in distribution pipe is managed, and sample-adding pipe is communicated by distribution pipe with syringe；The utility model solves existing blood transfusion cross matching and positive and negative ABO and RhD blood groups and irregular antibody examination experiment there is no special sample injector, it is extremely complex using common suction pipe or dropper operation, efficiency is low and the problem of easily error, there is provided cross matching and ABO and RhD blood groups and irregular antibody examination sample injector.
Description
Technical field
The present invention relates to medical experiment equipment, specifically cross matching and ABO and RhD blood groups and irregular antibody examination adds
Sample device.
Background technology
Up to the present, situation of all-level hospitals Blood Transfusion Dept. to be that blood transfusion cross match blood test, ABO be positive and negative and RhD bracket for blood grouping with
And in serum during three big experiment of irregular antibody examination be loaded using common plasticses suction pipe or plastic dropper, if by
Blood person needs donor bloods more than two person-portions, and extremely complex, every blood donor is tested in its cross matching done before transfusing blood
Cross matching experiment will be carried out between receptor and between every blood donor and blood donor, such as the experiment of y-bend one needs six
Branch transparent pipe, each transparent pipe sample-adding blood cell and serum once, need to be respectively loaded 12 times altogether, and the experiment of trident one needs sample-adding 24 times,
And blood cell and serum are pushed the wrong bit pairing mode and are added to supervisor and time pipe, it is seen that only sample-adding process is just very cumbersome, easily
Error, on the other hand, existing sample-adding process can not keeping sample, if sample-adding process error, the later stage counter can not look into.
Therefore, applicant once applied for a kind of multi-purpose disposable blood transfusion cross match blood test combination on 2 13rd, 2015
Device, and patent for invention has been obtained, a kind of special combination tester is provided for cross matching experiment, but there is no at present special
Sample injector, but use and be manually loaded one by one, efficiency is low and easy error.
The content of the invention
Present invention aim to solve the big experiment of transfusion safety three（Blood group cross matching is tested, ABO is positive and negative and RhD
Bracket for blood grouping and irregular antibody examination）Without special sample injector, it is numerous that sample-adding complex operation is carried out using common suction pipe or dropper
Trivial, easily error, later stage can not anti-the problem of looking into, there is provided cross matching and ABO and RhD blood groups and irregular antibody examination sample-adding
Device.
The present invention proposes three kinds of schemes.
Scheme one：Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector, it is closed at both ends with one
Horizontal positioned distribution pipe, it is provided with least two syringes side by side in distribution pipe, syringe is vertical with distribution pipe, syringe needle
Head position is located at below distribution pipe through distribution pipe, and the position on syringe in distribution pipe is provided with radial direction through hole, is distributing
Guan Shangyu syringes are provided with a sample-adding and managed side by side, and sample-adding pipe is communicated by distribution pipe with syringe.
In scheme one, sample-adding volume sample-adding amount according to needed for experiment that the syringe is located at below radial direction through hole is set.
In scheme one, the distribution bottom of the tube is provided with a storage capsule, and storage capsule communicates with distribution pipe.
Scheme two：Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector, it is horizontally disposed with one
Memotron, be provided with least two measuring cups side by side in memotron, measuring cup bottom is provided with vomit pipe, and vomit pipe passes downwards storage
Pipe, each vomit pipe are provided with valve A, are provided with a fixed mount outside memotron, vomit pipe lower end passes fixed mount, the storage
Deposit pipe to go out liquid flexible pipe provided with a feed liquor flexible pipe and one and communicate with memotron, feed liquor flexible pipe is set with the other end for going out liquid flexible pipe
There is a reagent bottle.
In scheme two, volume sample-adding amount according to needed for experiment of the measuring cup is set.
In scheme two, 1-3 valve B is optionally had additional on the vomit pipe.
In scheme two, described valve A, B are common stop valve or magnetic valve.
Scheme three：Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector, there are four side-by-side horizontals
Arrangement and distribution pipe closed at both ends, it is characterized in that：Four distribution pipes are not connected, in the left side of odd bits distribution pipe point
Not She You one sample-adding pipe, be respectively equipped with the right side of even bit distribution pipe one sample-adding pipe, set side by side in the centre of distribution pipe
There are three syringe fixed bits, a syringe is respectively provided with close to two position in first distribution pipe, in second distribution
A syringe is being provided with close to left side on pipe, middle position is provided with a syringe in the 3rd distribution pipe, the 4th
Middle and close right side are respectively provided with a syringe, first distribution pipe left side syringe and second distribution in individual distribution pipe
The injection port position of both syringes on pipe is mutually placed close together, syringe and the 4th distribution pipe in the 3rd distribution pipe
The injection port position of both middle syringes is mutually placed close together, syringe and the 4th distribution on the right side of first distribution pipe
The injection port position of both syringes on the right side of pipe is mutually placed close together, all syringe needle positions pass distribution pipe positioned at point
Pipe arrangement lower end, the position on syringe in distribution pipe are provided with radial direction through hole, and sample-adding is managed and communicated by distribution pipe with syringe.
In scheme three, four distribution pipes are by bonding or connector or are integrally formed and are combined as an entirety.
In scheme three, the labeling of " by clear " and " for clear " printed words, right side sample-adding pipe are posted on the left side sample-adding pipe respectively
The upper labeling for posting " supplying ball " and " by ball " printed words respectively.
The present invention is simple in construction, and manufacturing cost is low, disposable, securely and reliably, cross matching is carried out using the present invention
Tested with positive and negative ABO and RhD blood groups and irregular antibody examination, it is convenient and swift, it is not error-prone, after sample-adding terminates in experimentation
The sample remained in sample injector is conveniently taken pictures to scan and achieved, and the later stage counter can look into.
Brief description of the drawings
Fig. 1 is a kind of structural representation of the present invention program one；
Fig. 2 is the schematic diagram of the present invention program two；
Fig. 3 is the schematic diagram of the present invention program three；
Fig. 4 is the auxiliary schematic diagram of the present invention program three；
Fig. 5 is another structural representation of the present invention program one；
Fig. 6 is the experimental group clutch schematic diagram of y-bend one；
Fig. 7 is the experimental group clutch schematic diagram of a fork one；
Fig. 8 is Fig. 4 B-B schematic diagrames；
In figure：1- sample-adding pipes, 2- syringes, 3- distribution pipes, 4- storage capsules, 5- measuring cups, 6- memotrons, 7- valves A, 8- valve
Door B, 9- fixed mounts, 10- vomit pipes, 11- feed liquor flexible pipes, 12- go out liquid flexible pipe, 13- reagent bottles.
Embodiment
Embodiment 1
Referring to Fig. 1, the present invention has a horizontal positioned distribution pipe 3 closed at both ends, is provided with side by side extremely in distribution pipe 3
Few two syringes 2, syringe 2 is vertical with distribution pipe 3, and the syringe needle position of syringe 2 is located at the lower section of distribution pipe 3 through distribution pipe 3,
Position on syringe 2 in distribution pipe 3 is provided with radial direction through hole, is provided with a sample-adding side by side with syringe 2 in distribution pipe 3
Pipe 1, sample-adding pipe 1 are communicated by distribution pipe 3 with syringe 2.
Sample-adding volume sample-adding amount according to needed for experiment that syringe 2 described in the present embodiment is located at below radial direction through hole is set
It is fixed.
The bottom of distribution pipe 3 described in the present embodiment is provided with a storage capsule 4, and storage capsule 4 communicates with distribution pipe 3.
Operation principle：Sample is added in sample-adding pipe 1, sample is flowed into each syringe 2 naturally by distribution pipe 3,
Sample injector is directed at again the experimental group clutch of required sample-adding, successively pushing syringe 2, when the piston of syringe 2 shifts edge on through hole onto
When down promoting again, due to small more of radial direction through hole diameter above the aperture ratio of syringe needle position, therefore syringe needle position pressure ratio is radially led to
Big more of pressure at hole, so sample more in through hole is flowed into the storage capsule 4 of distribution pipe 3, up to the piston of syringe 2 shift onto it is logical
When hole lower edge is down pushed to bottom again, quantitative sample flows into experimental group clutch by syringe needle, now completes sample-adding.
When the present embodiment is used for ABO positive definite forms and the experiment of RhD bracket for blood grouping, operating procedure is as follows：
1st, take the ABO of Patent No. 201621065473.0 positive and negative and RhD antigens bloodtypes identification combiner one, thirdly
Be separately added into branch test tube containing anti-D, anti-A, anti-B standard serum；
2nd, the sample injector of the present invention containing 3 syringes is taken, blood cell suspension to be measured is added in pipe is loaded, then will sample-adding
Device is put in alignment test tube above combiner, successively adds the blood cell suspension in syringe in combiner；
3rd, combiner is placed on to take out after 15 minutes in 37 DEG C of insulating boxs and shaken up, then with 1000 turns/min centrifugally operateds；
4th, the situation that red blood cell sinks is observed, as substantially uniformity sinks down into ttom of pipe, gel is uniformly distributed, then is judged as not coagulating
Collection；It is judged as aggegation if the complete aggegation of red blood cell is on gel layer；As red blood cell disperses uneven coagulate among gel layer
Collection is also judged as aggegation.
When the present embodiment is used for ABO reverse types and irregular antibody examination experiment, operating procedure is as follows：
1st, take the ABO containing three test tubes positive and negative and RhD antigens bloodtypes identify two groups of combiner, and be emitted on rack for test tube
In, three, left side is separately added into normal erythrocytes A, red blood cell B, red blood cell AB, three, right side be separately added into containing anti-Igm and B1,
The red blood cell of B2, B3 reagent；
2nd, structure sample injector as shown in Figure 5 is taken, serum sample to be measured is added into sample-adding pipe 1, then by sample injector
The test tube mouth of combiner is directed at, pushing syringe is loaded；
3rd, combiner is placed in 37 DEG C of insulating boxs 15 minutes, shaken up, with centrifuge 1000 turns/min centrifugally operateds, so
Observation is taken out afterwards, and result of determination simultaneously keeps a record, and then mark is "+" for aggegation, and then mark is "-" for not aggegation；
The positive reverse types of ABO and RhD blood groups and irregular antibody screening results judge as shown in the table：
Embodiment 2
Referring to Fig. 2, the present invention has a horizontally disposed memotron 6, at least two measuring cups is provided with side by side in memotron 6
5, the bottom of measuring cup 5 is provided with vomit pipe 10, and vomit pipe 10 passes downwards memotron 6, and each vomit pipe 10 is provided with valve A7, storage
The outside of pipe 6 is provided with a fixed mount 9, and the lower end of vomit pipe 10 passes fixed mount 9, and the memotron 6 is provided with a feed liquor flexible pipe 11
Go out liquid flexible pipe 12 with one to communicate with memotron 6, feed liquor flexible pipe 11 is provided with a reagent bottle with the other end for going out liquid flexible pipe 12
13。
Increase is provided with two valve B8 on vomit pipe 10 in the present embodiment.
Valve A, B are common stop valve in the present embodiment.
Operation principle：Reagent bottle 13 is moved up, its bottom level is higher than the import of memotron 6, in reagent bottle 13
Sample is flowed into memotron 6 naturally by feed liquor flexible pipe 11, and now valve A7 and valve B8 are in closed mode, treat each
After measuring cup 5 is filled naturally, then reagent bottle 13 moved down, the drain pipe open height of memotron 6 is higher than reagent bottleneck, now
Unnecessary sample flow back into reagent bottle 13 due to difference in height naturally in memotron 6, then will sample-adding needed for sample injector alignment experiment
The test tube mouth of combiner, then the opening valve A7 and valve B8 of selectivity can complete to be loaded according to the actual requirements.
When the present embodiment is used for the match of y-bend one experiment, operating procedure is as follows：
1st, the multi-purpose disposable blood transfusion cross match blood test combiner 9 of Patent No. 201510077271.1 is taken to be combined into
The structural experiment combiner of y-bend one as shown in Figure 6, then take the sample injector six of the present embodiment, stick respectively white " 0 ",
" 1 ", " 2 " number and red " 0 ", " 1 ", " 2 " number labeling；
2nd, toward addition receptor's serum in the sample injector for marking white " 0 " number, add into the sample injector of mark white " 1 " number
Enter No. 1 blood donor's serum, No. 2 blood donor's serum are added into the sample injector of mark white " 2 " number, toward mark red " 0 " number
Receptor's blood cell suspension is added in sample injector, No. 1 blood donor's blood cell suspension is added into the sample injector of mark red " 1 " number, it is past
No. 2 blood donor's blood cell suspensions are added in the sample injector of mark red " 2 " number；
3rd, first white " 0 " number sample injector alignment combiner is horizontally-arranged, then opens valve and is loaded；
4th, second white " 1 " number sample injector alignment combiner is horizontally-arranged, then opens valve and is loaded；
5th, the 3rd white " 2 " number sample injector alignment combiner is horizontally-arranged, then opens valve and is loaded；
6th, red " 0 " number sample injector is directed at the first vertical setting of types of combiner, then opens valve and be loaded；
7th, red " 1 " number sample injector is directed at the second vertical setting of types of combiner, then opens valve and be loaded；
8th, red " 2 " number sample injector is directed at the 3rd vertical setting of types of combiner, then opens valve and be loaded；
9th, again with the present embodiment sample injector toward adding low solion in combiner（LIM）0.65ml, after being well mixed again
Cohesion amine aqueous solution is added,（Polybene）Solution two drips, and is well mixed；
10th, with special centrifugal machine by each row's small test tube centrifugally operated 10 seconds（3400 turns/min）, then taken out using special
Liquid pump takes out supernatant, and retains 0.1ml blood cell mixtures；
11st, each row's test tube is gently shaken manually, and range estimation red blood cell whether there is aggegation, must reformed if without aggegation；
12nd, Resuspending is added（Suspending agent）Two drops gently shake test tube and mix and observe result, such as in 60 seconds
Aggegation is scattered, and representative is to cause rejection aggregation match result to be harmonious by Polybene cohesion amine；As aggegation is not scattered, then to be red
The specific reaction that cell antigen antibody combines, match result are not consistent；
13rd, as reacted suspicious, sucked the sample into using sampling viewer in transparent plastic film capsule with micro- sem observation.
Embodiment 3
Referring to Fig. 4, the present invention has four side-by-side horizontal arrangements and distribution pipe 3 closed at both ends, four distribution pipes 3
It is not connected, a sample-adding pipe 1 is respectively equipped with the left side of odd bits distribution pipe 3, is set respectively on the right side of even bit distribution pipe 3
There is a sample-adding pipe 1, be provided with three fixed bits of syringe 2 side by side in the centre of distribution pipe 3, it is close in first distribution pipe 3
Two position is provided with two syringes 2, a syringe 2 is being provided with close to left side in second distribution pipe 3, at three point
Middle position is provided with a syringe 2 on pipe arrangement 3, and middle and close right side are provided with two notes in the 4th distribution pipe 3
Emitter 2, the syringe 2 on first left side syringe 2 of distribution pipe 3 and second distribution pipe 3 are combined as one group, the 3rd distribution
The syringe 2 among syringe 2 and the 4th distribution pipe 3 on pipe 3 is combined as one group, the injection on first right side of distribution pipe 3
Device 2 and the syringe 2 on the 4th right side of distribution pipe 3 are combined as one group, and all syringe needle positions of syringe 2 pass distribution pipe 3 and are located at
The lower end of distribution pipe 3, the position on syringe 2 in distribution pipe 3 are provided with radial direction through hole, and sample-adding pipe 1 passes through distribution pipe 3 with injecting
Device 2 communicates.
Four distribution pipes 3 are combined as an entirety by being bonded or being integrally formed described in the present embodiment.
The labeling of " by clear " and " for clear " printed words, right side sample-adding are posted on the pipe 1 of left side sample-adding described in the present embodiment respectively
The labeling of " supplying ball " and " by ball " printed words is posted on pipe 1 respectively.
Using sample injector of the present invention, it is as follows to carry out an one cross matching laboratory operating procedures of fork：
1st, take as shown in Figure 7 one to pitch a cross matching experiment combiner to be put into rack for test tube；
2nd, 2ml receptors serum is added on the left of first row and be loaded in pipe 1,2ml blood donor's serum is added to second row
In the sample-adding pipe 1 of left side, 1ml blood donor's blood cell suspension is added on the right side of first row in sample-adding pipe 1,1ml receptor's blood cells are hanged
Liquid is added on the right side of second row in sample-adding pipe 1；
3rd, sample injector is integrally moved on on rack for test tube, is directed at three test tubes of experimental group clutch, successively pushing syringe 2,
Complete sample-adding；
4th, subsequent process steps are similar with the step 9-13 of embodiment 2.
Claims (10)
1. cross matching and ABO and RhD blood groups and irregular antibody examination sample injector, closed at both ends horizontal positioned with one
Distribution pipe, it is characterized in that：It is provided with least two syringes side by side in distribution pipe, syringe is vertical with distribution pipe, syringe needle
Head position is located at below distribution pipe through distribution pipe, and the position on syringe in distribution pipe is provided with radial direction through hole, is distributing
Guan Shangyu syringes are provided with a sample-adding and managed side by side, and sample-adding pipe is communicated by distribution pipe with syringe.
2. cross matching according to claim 1 and ABO and RhD blood groups and irregular antibody examination sample injector, its feature
It is：Sample-adding volume sample-adding amount according to needed for experiment that the syringe is located at below radial direction through hole is set.
3. cross matching according to claim 1 and ABO and RhD blood groups and irregular antibody examination sample injector, its feature
It is：The distribution bottom of the tube is provided with a storage capsule, and storage capsule communicates with distribution pipe.
4. cross matching and ABO and RhD blood groups and irregular antibody examination sample injector, there is a horizontally disposed memotron,
It is characterized in that：At least two measuring cups are provided with memotron side by side, measuring cup bottom is provided with vomit pipe, and vomit pipe passes downwards storage
Pipe, each vomit pipe are provided with valve A, are provided with a fixed mount outside memotron, vomit pipe lower end passes fixed mount, the storage
Deposit pipe to go out liquid flexible pipe provided with a feed liquor flexible pipe and one and communicate with memotron, feed liquor flexible pipe is set with the other end for going out liquid flexible pipe
There is a reagent bottle.
5. cross matching according to claim 4 and ABO and RhD blood groups and irregular antibody examination sample injector, its feature
It is：The volume of measuring cup sample-adding amount according to needed for experiment is set.
6. cross matching according to claim 4 and ABO and RhD blood groups and irregular antibody examination sample injector, its feature
It is：1-3 valve B is optionally had additional on the vomit pipe.
7. cross matching and ABO and RhD blood groups and irregular antibody examination sample injector according to claim 4 or 6, it is special
Sign is：Described valve A, B are common stop valve or magnetic valve.
8. cross matching and ABO and RhD blood groups and irregular antibody examination sample injector, there are four side-by-side horizontal arrangements and both ends
The distribution pipe of closing, it is characterized in that：Four distribution pipes are not connected, and one is respectively equipped with the left of odd bits distribution pipe
Sample-adding pipe, is respectively equipped with a sample-adding pipe on the right side of even bit distribution pipe, and three injections are provided with side by side in the centre of distribution pipe
Device fixed bit, a syringe is respectively provided with close to two position in first distribution pipe, close in second distribution pipe
Left side is provided with a syringe, and middle position is provided with a syringe in the 3rd distribution pipe, in the 4th distribution pipe
Middle and it is respectively provided with a syringe close to right side, the injection on the left of first distribution pipe on syringe and second distribution pipe
The injection port position of both devices is mutually placed close together, the injection among syringe and the 4th distribution pipe in the 3rd distribution pipe
The injection port position of both devices is mutually placed close together, the note on the right side of syringe and the 4th distribution pipe on the right side of first distribution pipe
The injection port position of both emitters is mutually placed close together, and all syringe needle positions pass distribution pipe and are located at distribution pipe lower end,
Position on syringe in distribution pipe is provided with radial direction through hole, and sample-adding pipe is communicated by distribution pipe with syringe.
9. cross matching according to claim 8 and ABO and RhD blood groups and irregular antibody examination sample injector, its feature
It is：Four distribution pipes are by bonding or connector or are integrally formed and are combined as an entirety.
10. cross matching according to claim 8 and ABO and RhD blood groups and irregular antibody examination sample injector, its feature
It is：The labeling of " by clear " and " for clear " printed words is posted on the left side sample-adding pipe respectively, posts and " is supplied respectively on the sample-adding pipe of right side
The labeling of ball " and " by ball " printed words.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720941969.8U CN207007863U (en) | 2017-07-31 | 2017-07-31 | Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720941969.8U CN207007863U (en) | 2017-07-31 | 2017-07-31 | Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector |
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| Publication Number | Publication Date |
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| CN207007863U true CN207007863U (en) | 2018-02-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720941969.8U Withdrawn - After Issue CN207007863U (en) | 2017-07-31 | 2017-07-31 | Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107247154A (en) * | 2017-07-31 | 2017-10-13 | 刘大基 | Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector |
-
2017
- 2017-07-31 CN CN201720941969.8U patent/CN207007863U/en not_active Withdrawn - After Issue
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107247154A (en) * | 2017-07-31 | 2017-10-13 | 刘大基 | Cross matching and ABO and RhD blood groups and irregular antibody examination sample injector |
| WO2019024624A1 (en) * | 2017-07-31 | 2019-02-07 | 刘大基 | Cross-matching of blood, abo and rhd blood typing, and irregular antibody screening sample-adding apparatus |
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| AV01 | Patent right actively abandoned | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20180213 Effective date of abandoning: 20181218 |