CN206788183U - Self-priming Dry-type biochemical detection means - Google Patents
Self-priming Dry-type biochemical detection means Download PDFInfo
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- CN206788183U CN206788183U CN201720592536.6U CN201720592536U CN206788183U CN 206788183 U CN206788183 U CN 206788183U CN 201720592536 U CN201720592536 U CN 201720592536U CN 206788183 U CN206788183 U CN 206788183U
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Abstract
The utility model provides a kind of self-priming Dry-type biochemical detection means, including:Upper cover and bottom plate, limited post is provided with left and right sides of the bottom plate, the upper lid be may be detachably retained between the limited post at left and right sides of the bottom plate, and test paper is provided between the contact surface of base portion and the bottom plate on described;The bottom plate is provided with the groove for placing test paper between the limited post of the left and right sides, and at least one detection hole is provided with below the groove, and each detection hole is separate and has predetermined interval;The top of upper lid is provided with sample holes, and bottom is provided with sample outlet hole, is turned between sample holes and sample outlet hole by a flow-guiding channel.The utility model can realize that automatic ration draws sample to be measured, once test multiple projects and be loaded without extra using pipettor or suction pipe.
Description
Technical field
It the utility model is related to biochemistry detection field, and in particular to a kind of self-priming Dry-type biochemical detection means.
Background technology
The sample sample-adding of existing Dry-type biochemical detector bar is more to be transferred to sample to be detected with pipettor or quantitative straw
Need extra configuration pipettor or suction pipe in the sample application region of Dry-type biochemical detector bar, during Samples detection, have absorption during operation
Sample and the step of sample is transferred into test-strips, and pollution problem caused by pipette tips or suction pipe being present and manual operation is improper draws
Detection error caused by the sample-adding amount inaccuracy risen.A kind of Test paper device is the utility model is related to, there is quantitative absorption
Sample to be measured is loaded without extra using pipettor or suction pipe, solves to use pipettor or suction pipe during Test paper detection
Operation sample pollution and operating procedure the problem of sample-adding amount accuracy and when reducing detection.
At present, drying chemical reagent paper detection method, which is usually used in determining in quantitative or qualitative test liquid sample, whether there is certain
Composition, such as the glucose in blood sample, cholesterol, glutamic-pyruvic transaminase etc..The foundation of Dry-type biochemical detector bar can disposably be surveyed
Fixed sample size and the difference of test index species, it is divided into measure individual event and multipurpose test paper.Its general method of testing is to use
The sample to be detected of specified quantitative is added dropwise in the sample application region of bar by pipettor or quantitative straw, within a certain period of time visual observation
Or test out result using necessary instrument.The individual event test paper as disclosed in United States Patent (USP) US7087397 is used to determine blood
In HDL-C.Upper plate of the device with well and the lower plate with testing window disclosed in this patent,
Test paper is pressed against between the upper and lower plates.The detection means needs to use liquid-transfering gun or sample-adding pipe, and once sample-adding can only be surveyed
Try single project.US7494818, which discloses once sample-adding, can just detect the dry chemical detection means of multiple projects.Add including one
Sample hole and multiple test blocks, the sample of dropwise addition is evenly distributed to using the Distribution Layer between well and multiple test blocks multiple
On reagent block, so as to realize that once sample-adding completes the function of multiple detection projects.The detection means still need using liquid-transfering gun or
Sample-adding pipe is loaded.
A kind of detection means, including upper lid are disclosed in CN102680672A, the bottom plate that is combined is covered and positioned at upper with upper
Test paper between lid and bottom plate.On cover flow-guiding structure be provided with lower surface, in the well, flow-guiding structure, survey of upper lid
Have a try paper coating and detection zone between form fluid transfer, so as to realize, once sample-adding tests multiple projects.Should
Detection means stills need to be loaded using liquid-transfering gun or sample-adding pipe.
Disclosed in CN106198950A it is a kind of can realize automatic ration sample-adding detection means, including the first cover plate and
Second cover plate, control amount Loading channel is provided with the first cover plate.Include adding mouth and liquid outlet on the control amount Loading channel, extremely
It is few to include one section of capillary channel near adding mouth.There is sample-adding platform on first cover plate, adding mouth is positioned at sample-adding platform center.Sample-adding
When liquid sample by the capillary channel near adding mouth enter adding mouth in control amount Loading channel.Control amount Loading channel
Volume determines the volume of sample-adding.The more complicated needs of the detection means design increase sample-adding platform and extra capillary on device
Tube passage.Sample can produce residual in sample-adding platform and capillary channel during sample-adding causes actual sampling amount increase, is difficult to realize
Multinomial detection, operator can not also be visually observed that whether the sample inside Loading channel is enough.
Utility model content
The utility model provides a kind of self-priming Dry-type biochemical detection means, it is possible to achieve automatic ration is drawn and treats mark
This, is once tested multiple projects and is loaded without extra using pipettor or suction pipe.Test device need not increase sample-adding
Platform and extra capillary channel, avoid sample from remaining.Operator can directly observe the sample state inside Loading channel,
Avoid that postponing occurs in result caused by specimen amount deficiency or mistake, concrete scheme are as follows:
A kind of self-priming Dry-type biochemical detection means, including:
Upper cover and bottom plate, limited post is provided with left and right sides of the bottom plate, and the upper lid is detachably secured
Between the limited post at left and right sides of the bottom plate, test is provided between the contact surface of base portion and the bottom plate on described
Test paper;
The bottom plate is provided with the groove for placing test paper between the limited post of the left and right sides, and in the groove
Lower section is provided with least one detection hole, and each detection hole is separate and has predetermined interval;
The top of upper lid is provided with sample holes, and bottom is provided with sample outlet hole, is led between sample holes and sample outlet hole by one
Circulation road turns on.
Further, the sample holes are raised in the upper caping end surfaces.
Further, the flow-guiding channel is the transparent cavity through the upper lid whole thickness.
Further, the length of the flow-guiding channel is 3-30 millimeters, and volume is 3-200 microlitres.
Further, the flow-guiding channel selects the material for including hydrophilic substance to be made, or the flow-guiding channel is surface
By the transparent material of hydrophilic treated.
Further, the test paper includes the coating at top and an at least reaction block for bottom, each reaction block phase
Mutual independence and there is predetermined interval;
The coating contacts with the sample outlet hole, each detection hole of position face of each reaction block.
Further, the section of sample holes, sample outlet hole and flow-guiding channel is shaped as circular, polygon or elliptical shape.
Using technical scheme provided by the utility model, there is quantitative absorption sample to be measured without extra use
Pipettor or suction pipe sample-adding, polluted when solving Test paper detection using the sample of the operation of pipettor or suction pipe and sample-adding amount is accurate
The problem of true property and operating procedure when reducing detection.
Brief description of the drawings
, below will be to embodiment or prior art in order to illustrate more clearly of the technical scheme in the embodiment of the utility model
The required accompanying drawing used is briefly described in description, it should be apparent that, drawings in the following description are only that this practicality is new
Some embodiments of type, for those of ordinary skill in the art, without having to pay creative labor, can be with
Other accompanying drawings are obtained according to these accompanying drawings.
Fig. 1 is a kind of exploded perspective view of self-priming each part of Dry-type biochemical detection means provided by the utility model;
Fig. 2 is a kind of schematic diagram of the combination of self-priming Dry-type biochemical detection means provided by the utility model;
Fig. 3-4 is the schematic diagram covered on the utility model;
Fig. 5-6 is the schematic diagram of the utility model bottom plate.
Embodiment
In the following description, a large amount of concrete details are given more thoroughly to manage the utility model to provide
Solution.It is, however, obvious to a person skilled in the art that the utility model can be without one or more of these thin
Save and be carried out.In other examples, in order to avoid obscuring with the utility model, for more well known in the art
Technical characteristic is not described.
In order to thoroughly understand the utility model, detailed step and detailed structure will be proposed in following description,
To explain the technical solution of the utility model.Preferred embodiment of the present utility model is described in detail as follows, but except these
Outside being described in detail, the utility model can also have other embodiment.
Shown in reference picture 1- Fig. 6, the utility model provides a kind of self-priming Dry-type biochemical detection means, including:
Upper lid 10 and bottom plate 20, the left and right sides of bottom plate 20 are provided with limited post 21, and upper lid 10 is removably solid
It is scheduled between the limited post 21 of the left and right sides of bottom plate 20, test examination is provided between the upper bottom of lid 10 and the card access surface of bottom plate 20
Paper;
Bottom plate is provided with the groove 25 for placing test paper between the limited post 21 of 20 left and right sides, and recessed at this
The lower section of groove 25 is provided with least one detection hole 22, and each detection hole 22 is separate and has predetermined interval.Pass through detection zone
In the certain interval of test block phase mutual, prevent the cross pollution between test block;
The top of upper lid 10 is provided with sample holes 12, and bottom is provided with sample outlet hole 14, sample holes 12 and sample outlet hole 14 it
Between pass through a flow-guiding channel (or microchannel) 11 turn on.
In the optional embodiment of the utility model one, the internal cavity surface of flow-guiding channel 11 for hydrophilic material or including
There is hydrophilic substance.Liquid is diffused in microchannel by capillarity, and the cavity content volume of microchannel determines production
The sample-adding amount of product.In optional embodiment, the length of flow-guiding channel 11 is 3-30 millimeters, and volume is 3-200 microlitres.
In the optional embodiment of the utility model one, the sample holes are raised in the upper caping end surfaces.
In the optional embodiment of the utility model one, flow-guiding channel 11 is the transparent chamber through the upper whole thickness of lid 10
Body.
In the optional embodiment of the utility model one, flow-guiding channel 11 is made from the material for including hydrophilic substance, or
The flow-guiding channel can be transparent material of the surface Jing Guo hydrophilic treated.
In the optional embodiment of the utility model one, as shown in figure 1, test paper includes coating 30 and the bottom at top
An at least reaction block 40 in portion, each reaction block 40 is separate and has predetermined interval;The coating contacts with sample outlet hole 14, with
It is easy to transmit the liquid in flow-guiding channel 11 to coating 30, each detection hole 22 of position face of each reaction block 40, reacts
Block 22 is covered in the detection hole 22 of the lower section of groove 25, is easy to instrument to be examined by detection hole 22 to each reaction block 40
Survey.Wherein, material is to absorb any material of liquid sample used by coating 30, such as gauze, filter paper, glass, is gathered
Ester film, non-woven fabrics etc., preferably polyester film.
In the optional embodiment of the utility model one, the detection zone that each detection hole 22 is formed is close to the one of sample outlet hole 14
Side, be advantageous to liquid in microchannel and preferably infiltrate into test paper.
In the optional embodiment of the utility model one, the shape in the section of sample holes 12, sample outlet hole 14 and flow-guiding channel 11
Shape is the other shapes such as circular, polygon or elliptical shape.
When being detected using self-priming Dry-type biochemical detection means provided by the utility model, liquid sample touches inspection
Survey on device after the well that covers, drawn sample into microchannel by capillarity, then sample is reached by sample outlet hole
The coating 30 of test paper, and sample is diffused to by one or more coatings 30 by the diffusion of the material of coating 30
The reaction block 40 of bottom, the color change of reaction block 40 is obtained a result in the range of the detection aperture that instrument passes through bottom base plate, side
Testing staff multiple detection zones are detected and sampled.
Test paper is placed in the groove 25 of bottom plate 20, and keeps the coating 30 of test paper upward, bottom it is anti-
Each detection hole 22 of the face of block 40 is answered, is afterwards blocked upper lid 10 between limited post 21 on the base plate 20.Drawn by sample holes 12
Sample to be tested, sample to be tested flow through flow-guiding channel 11 and the coating 30 on test paper surface are penetrated into by sample outlet hole 14.Treat
Test sample sheet reaches each reaction block 40 of bottom after the scattering and permeating of coating 30.Color caused by chemical reaction in reaction block
Change can be detected by necessary instrument.
The utility model can realize that automatic ration draws sample to be measured, once test multiple projects without extra
It is loaded using pipettor or suction pipe.Test device need not increase sample-adding platform and extra capillary channel, avoid sample residual
Stay.Operator can directly observe the sample state inside Loading channel, avoid result caused by specimen amount deficiency from postponing
Or mistake.
Preferred embodiment of the present utility model is described above.It is to be appreciated that the utility model not office
It is limited to above-mentioned particular implementation, wherein the equipment and structure be not described in detail to the greatest extent are construed as using the common side in this area
Formula is practiced;Any those skilled in the art, in the case where not departing from technical solutions of the utility model ambit, all may be used
Technical solutions of the utility model are made with many possible changes and modifications using the methods and technical content of the disclosure above, or is repaiied
The equivalent embodiment of equivalent variations is changed to, this has no effect on substantive content of the present utility model.Therefore, it is every without departing from this practicality
The content of new technique scheme, according to the technical essence of the utility model to any simple modification made for any of the above embodiments, etc.
With change and modification, still fall within technical solutions of the utility model protection in the range of.
Claims (7)
- A kind of 1. self-priming Dry-type biochemical detection means, it is characterised in that including:Upper cover and bottom plate, limited post is provided with left and right sides of the bottom plate, and the upper lid may be detachably retained at institute Between stating the limited post at left and right sides of bottom plate, test examination is provided between the contact surface of base portion and the bottom plate on described Paper;The bottom plate is provided with the groove for placing test paper between the limited post of the left and right sides, and below the groove At least one detection hole is provided with, each detection hole is separate and has predetermined interval;The top of upper lid is provided with sample holes, and bottom is provided with sample outlet hole, is led between sample holes and sample outlet hole by a water conservancy diversion Road turns on.
- 2. self-priming Dry-type biochemical detection means as claimed in claim 1, it is characterised in that the sample holes are raised in described Upper caping end surfaces.
- 3. self-priming Dry-type biochemical detection means as claimed in claim 1, it is characterised in that the flow-guiding channel is through institute State the transparent cavity of lid whole thickness.
- 4. self-priming Dry-type biochemical detection means as claimed in claim 1, it is characterised in that the length of the flow-guiding channel is 3-30 millimeters, volume are 3-200 microlitres.
- 5. self-priming Dry-type biochemical detection means as claimed in claim 3, it is characterised in that the flow-guiding channel, which is selected, to be included The material of hydrophilic substance is made, or the flow-guiding channel is transparent material of the surface Jing Guo hydrophilic treated.
- 6. self-priming Dry-type biochemical detection means as claimed in claim 1, it is characterised in that the test paper includes top Coating and bottom an at least reaction block, each reaction block independently of each other and has a predetermined interval;The coating contacts with the sample outlet hole, each detection hole of position face of each reaction block.
- 7. self-priming Dry-type biochemical detection means as claimed in claim 1, it is characterised in that sample holes, sample outlet hole and water conservancy diversion The section of passage is shaped as circular, polygon or elliptical shape.
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CN201720592536.6U CN206788183U (en) | 2017-05-25 | 2017-05-25 | Self-priming Dry-type biochemical detection means |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107064484A (en) * | 2017-05-25 | 2017-08-18 | 杭州博旭生物技术有限公司 | Self-priming Dry-type biochemical detection means |
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Cited By (1)
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CN107064484A (en) * | 2017-05-25 | 2017-08-18 | 杭州博旭生物技术有限公司 | Self-priming Dry-type biochemical detection means |
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