CN206612985U - Renal replacement therapies control the device of CBF and dialysate flow - Google Patents
Renal replacement therapies control the device of CBF and dialysate flow Download PDFInfo
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- CN206612985U CN206612985U CN201621376911.5U CN201621376911U CN206612985U CN 206612985 U CN206612985 U CN 206612985U CN 201621376911 U CN201621376911 U CN 201621376911U CN 206612985 U CN206612985 U CN 206612985U
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Abstract
The utility model provides the device that a kind of renal replacement therapies control CBF and dialysate flow, including dialyzer, bloodletting tube, blood return tube, blood pump, dialysis fluid container, waste fluid container, dialyzate input pipe, dialyzate efferent duct, dialysate flow pump and waste drains pump.Bypass is provided with a detection pipe on the bloodletting tube, and the blood for extracting patient imports a blood testing module；The blood testing module is connected by data wire with a computer system, blood pump and the dialysate flow pump is connected to first controller and second controller, and first controller and second controller are connected by data wire with the computer system respectively.The application can predict target Kt/V values by the actual physiological parameter of patient, it is possible to by controller adjust automatically CBF and dialysate flow, so that actual measurement Kt/V values are fast and accurately consistent with target Kt/V values, reach expected dialysis treatment effect.
Description
Technical field
The utility model is related to a kind of medicine equipment, especially a kind of renal replacement therapies control CBF and dialyzate stream
The device of amount.
Background technology
Kidney trouble is the great chronic disease for seriously endangering human health, is generally treated with renal replacement therapy.Kidney
Alternative medicine continuous, slow water and solute removed in blood generally by way of extracorporeally circulating blood is dialysed, to substitute kidney
Dirty function, is preferably minimized the influence of solute concentration and volume change to body in blood.In renal replacement therapies to dialyse into
It is the important method for ensureing therapeutic quality that row adequacy, which is assessed,.In the renal replacement therapies process for such as uremic patient
In, in order to improve the life quality of MHD (HD) patient.It must accomplish that dialysis is abundant.Dialysis adequacy in chronic is influence
The key factor of whole end stage renal patient prognosis, large-scale international, multicenter haemodialysis research data display：Whole latter stage kidney
Dirty patient, which receives sufficient hemodialysis, can reduce the morbidity and mortality of complication.Adequacy is carried out to haemodialysis
Assessment is to improve dialysis, it is ensured that the important method of dialysis quality.
The A of CN 102159260 disclose it is a kind of be used in renal replacement therapies the method for early prediction Kt/V parameters and
Referred in equipment, the prior art, in order to estimate dialysis adequacy in chronic, it is necessary to the opening relationships between dialysis dosage and patient's effect
Parameter.What people were received the most is used to estimate that it is Kt/V to transmit dialysis amount or the parameter of dosage, and wherein K is effective urine
Plain clearance rate (clearance), t is treatment time, and V is the urine matched with total body water (total body water)
Plain distribution volume.The prior art provides a kind of algorithm model of early prediction Kt/V parameters, and it is used by measuring
The relevant parameter of liquid is analysed, the Kt/V parameters after dialysis are predicted by algorithm model, is then joined with the Kt/V after actual dialysis
Number is compared.However, the algorithm that the prior art is provided, is based on the measurement data of used dialyzate, lack patient
Direct blood data, the Kt/V parameters that prediction is obtained can not reflect the actual conditions of patient, actual Kt/V indexs after treatment
There is relatively large deviation with prediction target Kt/V indexs, it is impossible to accurate to reach expected dialysis treatment effect.Need that Kt/V will be being surveyed
On the basis of index and target Kt/V indexs are compared, the numerical value of CBF and dialysate flow with reference to before, after
Dialysis in constantly carry out tentative trial and error adjustment by rule of thumb, to make actual measurement Kt/V values and setting target Kt/V values tend to one
Cause.Generally require repeatedly to be repeated, step is complicated, and inaccurate, it is impossible to adapt to being continually changing for patient body.
Utility model content
The technical problems to be solved in the utility model is to provide a kind of renal replacement therapies control CBF and dialyzate stream
The device of amount, so that the problem of being formerly mentioned is reduced or avoided.
In order to solve the above technical problems, the utility model proposes a kind of renal replacement therapies control CBF and dialyzate
The device of flow, including dialyzer, bloodletting tube, blood return tube, blood pump, dialysis fluid container, waste fluid container, dialyzate input pipe, thoroughly
Analyse liquid efferent duct, dialysate flow pump and waste drains pump；Wherein, blood flows to the blood of the dialyzer by the bloodletting tube
Patient is returned in chamber and by the blood return tube, the flow of blood circuit is controlled by the blood pump；Dialyzate is from the dialysis
Liquid container takes the dialysate chamber of the dialyzer to by the dialyzate input pipe, and the dialysate chamber is led to the blood chamber
Semipermeable membrane is crossed to separate；Dialysate flow is controlled by the dialysate flow pump；From the used of dialysate chamber outflow
Analysis liquid is transported to the waste fluid container by the dialyzate efferent duct, and the flow of used dialyzate is by the waste drains pump control
System, wherein, bypass is provided with a detection pipe on the bloodletting tube, for taking trouble by the detection pipe pumping in the detection pipe
The blood of person imports in a blood testing module, the blood testing module sensor with detection blood parameters；It is described
Blood testing module is connected by data wire with a computer system, and blood pump and the dialysate flow pump is connected to one
Individual first controller and second controller, first controller and second controller pass through data wire and the computer respectively
System is connected.
Preferably, the detection pipe is connected with two or more blood testing modules.
Preferably, the computer system has Data Input Interface, and the Data Input Interface is distinguished by data wire
It is connected with the blood pump and dialysate flow pump.
The application can predict target Kt/V values, it is possible to adjust automatically by controller by the actual physiological parameter of patient
Whole CBF and dialysate flow, so that actual measurement Kt/V values are fast and accurately consistent with target Kt/V values, reach expected saturating
Analyse therapeutic effect.
Brief description of the drawings
The following drawings is only intended to, in doing the utility model schematic illustration and explanation, not limit model of the present utility model
Enclose.Wherein,
Fig. 1 is shown controls CBF and saturating according to the renal replacement therapies of a specific embodiment of the present utility model
Analyse the structural representation of the device of flow quantity.
Embodiment
In order to be more clearly understood to technical characteristic of the present utility model, purpose and effect, now control is illustrated
Embodiment of the present utility model.Wherein, identical part uses identical label.
The device that CBF and dialysate flow are controlled according to renal replacement therapies of the present utility model as shown in Figure 1
In, the blood of patient is extracted carry out extracorporal circulatory system, and blood is flowed in the blood chamber 30 of dialyzer 3 simultaneously by bloodletting tube 32
Patient is returned to by blood return tube 31.The flow of blood circuit is controlled by blood pump 33.Dialyzate is from dialysis fluid container 12 by saturating
Analysis liquid input pipe 20 takes the dialysate chamber 29 of dialyzer 3 to, and dialysate chamber 29 is separated by semipermeable membrane with blood chamber 30, passed through
Osmosis takes away the harmful substance in blood by dialyzate.Wherein, dialysate flow is controlled by dialysate flow pump 21.
The used dialyzate flowed out from dialysate chamber 29 by dialyzate efferent duct 36 is transported to waste fluid container 13, used dialyzate
Flow controlled by waste drains pump 34.
Unlike the prior art, bypass is provided with a detection pipe 40 on the bloodletting tube 32 of the application, for leading to
The blood that the detection tube pump 41 crossed in detection pipe 40 extracts patient imports a blood testing module 42, the blood testing module
There is the sensor of detection blood parameters, such as urea sensor in 42.The blood testing module 42 by data wire with
Such as one computer system 2 is connected, the blood parameters that the detection of blood testing module 42 is obtained, the urea concentration in blood, is led to
Cross data wire and input to computer system 2, target Kt/V values are predicted by the algorithm model of the software in computer system 2.
Wherein, the algorithm model of the software in computer system 2 can use any existing algorithm model, for example
Existing algorithm model disclosed in the A of CN 102159260.For example, based on the existing algorithm model, body fluid volume, blood can be passed through
Dialysis treatment time, dehydrating amount, dialyzer transfer area coefficient, CBF, this six parameters of dialysate flow are next
The serum urea concentration at the end of hemodialysis is calculated, prediction target Kt/V values are obtained by serum urea concentration.Due to
Utility model not protection algorism, prior art is quoted herein just to meet it is open sufficiently require, and be not belonging to the application
Wish the content of protection, those skilled in the art can lead to the existing algorithm model according to prior art and common knowledge
Cross any appropriate computer language to be written as in software input computer system, prediction target Kt/V is obtained to calculate
Value.
In another specific embodiment of the application, detection pipe 40 is connected with two or more blood testing moulds
Block (not shown), each blood testing module has the sensor for detecting different blood parameters respectively.
In addition, also there is Data Input Interface (not shown), for by the physiological parameter of patient in computer system 2
Computer system is inputted, such as the body weight before and after patients with hemodialysis, dialysis time, CBF, dialysate flow.It is specific at one
In embodiment, the Data Input Interface is connected with blood pump 33 and dialysate flow pump 21 respectively by data wire (not to be shown in figure
Go out), directly to obtain CBF and dialysate flow data, without manual intervention, improve the accuracy of data, it is to avoid people
Work operational error.
When patient carries out renal replacement therapies by the device of the application, on the day of dialysis, it can be examined by blood
The Data Input Interface surveyed in module 42 and computer system 2, by the body weight of Before and after dialysis, dialysis time, CBF, dialysis
Flow quantity, the urea of the haemodialyser used is always transported area coefficient and recorded.Dialysis in blood test results
Front and rear urea nitrogen concentration, and above-mentioned Before and after dialysis body weight, dialysis time, CBF, dialysate flow, and haemodialysis
The urea of device always transports area coefficient together, can calculate the body fluid volume parameter of patient.Can be further by body fluid volume parameter
It is determined that CBF and dialysate flow in order to reach prediction target Kt/V values.
Above calculating process can be calculated by the software in computer system 2 and obtained, and the calculating process can be used
Foregoing existing algorithm model or other any existing computation models.For example, according to foregoing existing algorithm model, leading to
Cross body fluid volume, hemodialysis treatment period, dehydrating amount, dialyzer transfer area coefficient, CBF, dialysate flow
Serum urea concentration (serum urea concentration determines prediction target Kt/V values) at the end of six parameters calculating hemodialysis,
The 7th parameter prediction target Kt/V value namely can be obtained by six parameters, in turn, it is known that prediction target Kt/V
Value, determines remaining five parameter, it is possible to last parameter needed for obtaining.For example, passing through blood dialysis before
In it is actually detected go out numerical value, that is, dialysis at the beginning and end of serum urea concentration, hemodialysis treatment period, dehydration
Amount, dialyzer transfer area coefficient, CBF, dialysate flow, etc. all parameters beyond body fluid volume all obtain
In the case of, body fluid volume to analyze can be calculated by model.In next formal progress haemodialysis, it will calculate before
Body fluid volume substitute into model, while by the estimated hemodialysis treatment period of formal haemodialysis, subscribe dehydrating amount, use it is saturating
Parser transfer area coefficient, reservation CBF, target prediction Kt/V values, prediction mesh can be drawn by being calculated by model
Mark the corresponding dialysate flow of Kt/V values.Based on same principle, CBF will be subscribed and dialysate flow is exchanged, will be calculated before
The body fluid volume that goes out substitutes into model, while by the estimated hemodialysis treatment period of formal haemodialysis, subscribing dehydrating amount, using
Dialyzer transfer area coefficient, reservation dialysate flow, target Kt/V, are predicted by model that can calculate
The corresponding CBF of target Kt/V values.
In a preferred embodiment, blood pump 33 and dialysate flow pump 21 of the present utility model are connected to one
One controller 51 and second controller 52, first controller 51 and second controller 52 pass through data wire and computer respectively
System 2 is connected.When by computer system 2 calculate obtain in order to reach prediction target Kt/V values CBF and dialysate flow
Afterwards, the first controller 51 and second controller 52 is controlled to adjust the CBF and thoroughly of blood pump 33 respectively by computer instruction
Analyse the dialysate flow of flow quantity pump 21, without manual intervention, realize automatically during renal replacement therapies CBF and
The control of dialysate flow.
The renal replacement therapies control CBF and the device of dialysate flow of the application, can pass through the actual physiology of patient
Parameter, predicts target Kt/V values, it is possible to by controller adjust automatically CBF and dialysate flow, so that actual measurement Kt/V
Value is fast and accurately consistent with target Kt/V values, reaches expected dialysis treatment effect.When actual measurement Kt/V values and target Kt/V values
There is deviation, can be by surveying CBF and dialysate flow that the anti-push controller of Kt/V values needs to adjust, by changing for several times
Generation control can move closer to the actual measurement Kt/V values of patient and reach target Kt/V values, the device of the application it is this oneself
Dynamic iteration control can overcome adjustment CBF by rule of thumb and dialysate flow, adjustment dialysis number of times length completely, cost is high lacks
Fall into.
Although it will be appreciated by those skilled in the art that the utility model is described in the way of multiple embodiments
, but not each embodiment is only comprising an independent technical scheme.So narration is just for the sake of clear in specification
For the sake of, the skilled in the art should refer to the specification as a whole is understood, and by skill involved in each embodiment
Art scheme, which is regarded as, can be mutually combined into the mode of not be the same as Example to understand protection domain of the present utility model.
The schematical embodiment of the utility model is the foregoing is only, model of the present utility model is not limited to
Enclose.Any those skilled in the art, the equivalent variations made on the premise of design of the present utility model and principle is not departed from,
Modification all should belong to the scope of the utility model protection with combining.
Claims (3)
1. the device of a kind of renal replacement therapies control CBF and dialysate flow, including dialyzer (3), bloodletting tube (32),
Blood return tube (31), blood pump (33), dialysis fluid container (12), waste fluid container (13), dialyzate input pipe (20), dialyzate efferent duct
(36), dialysate flow pump (21) and waste drains pump (34)；Wherein, blood flows to the dialyzer by the bloodletting tube (32)
(3) patient is returned in blood chamber (30) and by the blood return tube (31), the flow of blood circuit is by the blood pump (33)
Control；Dialyzate takes the saturating of the dialyzer (3) to from the dialysis fluid container (12) by the dialyzate input pipe (20)
Sap cavity (29) is analysed, the dialysate chamber (29) is separated with the blood chamber (30) by semipermeable membrane；Dialysate flow is by described
Dialysate flow pump (21) is controlled；The used dialyzate flowed out from the dialysate chamber (29) passes through the dialyzate efferent duct
(36) waste fluid container (13) is transported to, the flow of used dialyzate is controlled by the waste drains pump (34), it is characterised in that
Bypass is provided with a detection pipe (40) on the bloodletting tube (32), for passing through the detection tube pump in the detection pipe (40)
(41) blood for extracting patient is imported in a blood testing module (42), the blood testing module (42) with detection blood
The sensor of parameter；The blood testing module (42) is connected by data wire with a computer system (2), the blood pump
And dialysate flow pump (21) is connected to first controller (51) and second controller (52), first control (33)
Device (51) processed and second controller (52) are connected by data wire with the computer system (2) respectively.
2. the device of renal replacement therapies control CBF as claimed in claim 1 and dialysate flow, it is characterised in that institute
State detection pipe (40) and be connected with two or more blood testing modules (42).
3. the device of renal replacement therapies control CBF as claimed in claim 1 and dialysate flow, it is characterised in that institute
Computer system (2) is stated with Data Input Interface, the Data Input Interface by data wire respectively with the blood pump (33)
With dialysate flow pump (21) connection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621376911.5U CN206612985U (en) | 2016-12-14 | 2016-12-14 | Renal replacement therapies control the device of CBF and dialysate flow |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621376911.5U CN206612985U (en) | 2016-12-14 | 2016-12-14 | Renal replacement therapies control the device of CBF and dialysate flow |
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| CN206612985U true CN206612985U (en) | 2017-11-07 |
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| Application Number | Title | Priority Date | Filing Date |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109147884A (en) * | 2018-09-10 | 2019-01-04 | 北京英福美信息科技股份有限公司 | A kind of adequacy appraisal procedure and system |
| CN112121250A (en) * | 2019-06-25 | 2020-12-25 | 纬创资通股份有限公司 | Method for predicting dehydration amount for hemodialysis and electronic device using the same |
| CN112807503A (en) * | 2020-07-28 | 2021-05-18 | 高艳云 | Dialysis mode adjustment system using numerical analysis |
-
2016
- 2016-12-14 CN CN201621376911.5U patent/CN206612985U/en active Active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109147884A (en) * | 2018-09-10 | 2019-01-04 | 北京英福美信息科技股份有限公司 | A kind of adequacy appraisal procedure and system |
| WO2020052433A1 (en) * | 2018-09-10 | 2020-03-19 | 北京英福美信息科技股份有限公司 | Adequacy assessment method and system |
| CN109147884B (en) * | 2018-09-10 | 2021-04-02 | 北京英福美信息科技股份有限公司 | Sufficiency evaluation method and system |
| CN112121250A (en) * | 2019-06-25 | 2020-12-25 | 纬创资通股份有限公司 | Method for predicting dehydration amount for hemodialysis and electronic device using the same |
| CN112121250B (en) * | 2019-06-25 | 2023-09-29 | 纬创资通股份有限公司 | Dehydration amount prediction method for hemodialysis and electronic device using the same |
| CN112807503A (en) * | 2020-07-28 | 2021-05-18 | 高艳云 | Dialysis mode adjustment system using numerical analysis |
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