CN207429440U - A kind of Solute removal monitoring system of blood cleaning equipment - Google Patents

A kind of Solute removal monitoring system of blood cleaning equipment Download PDF

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Publication number
CN207429440U
CN207429440U CN201720177006.5U CN201720177006U CN207429440U CN 207429440 U CN207429440 U CN 207429440U CN 201720177006 U CN201720177006 U CN 201720177006U CN 207429440 U CN207429440 U CN 207429440U
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liquid
blood
outlet
entrance
blood filter
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尹良红
云琛
胡波
刘璠娜
管保章
孟宇
李云逸
云大信
贝特霍尔德·霍克
沃尔夫冈·波默
默罕默德·埃尔-萨耶德·阿卜杜勒·法塔赫
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Jinan University
University of Jinan
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Jinan University
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Abstract

A kind of Solute removal the utility model discloses blood cleaning equipment monitors system, including blood circuit, blood filter, displacement liquid circuit, dialyzate supply switching circuit and waste liquid discharge circuit, the first conductive detection device is serially connected between the dialyzate supply switching circuit and the second entrance of the blood filter, the second conductive detection device is serially connected between the dialyzate supply switching circuit and the second outlet of the blood filter.The utility model sets the first conductive detection device and the second conductive detection device respectively by the second entrance and second outlet in blood filter, to detect the electrical conductivity of the second entrance of the blood filter and second outlet respectively, and pass through to calculate and can monitor Solute removal state in real time, it can be achieved that in real time to removing the advantageous effect that is monitored of concentration of solute.

Description

A kind of Solute removal monitoring system of blood cleaning equipment
Technical field
The utility model is related to blood purification technology fields, refer in particular to a kind of Solute removal monitoring of blood cleaning equipment System.
Background technology
Blood cleaning equipment be by blood by a kind of allow, small-molecule substance by hollowfibre semi-permeable membrance in Center portion point, allows the isotonic liquid (such as dialyzate, displacement liquid, peritoneal dialysis liquid, equilibrium liquid) of preparation, passes through the outer of hollow-fibre membrane Side, under the action of the osmotic pressure and transmembrane pressure by the principles such as Mass, convection current and ultrafiltration remove large quantity of moisture in patient body and in, Small molecule toxins maintain internal water, electrolyte and alkali acid balance, to reach the therapeutic device of blood purification.Current blood is net Change equipment and be divided into hemodialysis apparatus (being divided into as haemodialysis control unit and hemodialysis filter) and continuation blood cleaning equipment (CRRT machines).
The isotonic liquid isotonic liquid of currently used blood cleaning equipment need to be turned by computer system in fixed ratio The rotation of speed control A liquid pumps, B liquid pumps and reverse osmosis water liquid pump, can be only achieved accurately with liquid.If the rotating speed of three liquid pumps is slightly micro- Little deviation is asynchronous, will cause the strength of fluid prepared that very big offset occurs, while can influence solute exchange, clearance rate On-line monitoring, seriously affect the effect for the treatment of or even the life security of patient.
Current haemodialysis control unit needs contratoxin elimination effect to be monitored at work, to monitor the effect for the treatment of, There are mainly two types of methods for existing on-line monitoring toxin removing:1) it is, to export blood drawing in the blood entry port and blood of dialyzer respectively It sends to chemical examination and removes situation to understand toxin;2), in the dialyzate entrance end installation conductivity sensor monitoring electricity of dialyzer The variation of conductance, to calculate the clearance rate of toxin.Because the law of conservation of matter, the removing of a urea molecule is with one The change of Na ion concentration both carried out urea-sodium ion exchange across semi-permeable membrane.It is just necessary in order to monitor the change of conductivity Change the concentration of concentrate dialysate to monitor the change of dialyzate conductivity, this urea removes monitoring mode and is required to change thoroughly Liquid concentration is analysed, therapeutic effect can be had adverse effect on.
Utility model content
The purpose of this utility model is that solve the disadvantage that it is above-mentioned, provide it is a kind of it is simple in structure, realize monitoring and detection essence Spend the Solute removal monitoring system of high blood cleaning equipment.
Following technical scheme can be used to reach in the purpose of this utility model:
A kind of blood cleaning equipment Solute removal monitoring system, including blood circuit, blood filter, displacement liquid circuit, thoroughly Liquid supply switching circuit and waste liquid discharge circuit are analysed, the first entrance of the blood filter is cut by blood circuit and dialyzate supply It gains the outlet on road and the artery connection of human body, the first outlet of the blood filter connected with the entrance passes through blood circuit and people The vein connection of body;The second entrance of the blood filter supplies switching circuit by dialyzate and the outlet in displacement liquid circuit connects Logical, the second outlet of the blood filter connected with the entrance supplies switching circuit by dialyzate and waste liquid is discharged circuit and outwards arranged Go out;The dialyzate supply switching circuit includes at least two-way supply loop, each road supply loop alternating and the second of blood filter Entrance is connected or closed, and each road supply loop is alternately connected or closed with the second outlet of blood filter, is formed and is switched continuous supply Answer structure;The first Conductivity detection dress is serially connected between the dialyzate supply switching circuit and the second entrance of the blood filter It puts, the second conductive detection device is serially connected between the dialyzate supply switching circuit and the second outlet of the blood filter.
Further, the supply loop includes cylinder body and solenoid valve, the cylinder interior be equipped with elastic interlayer and by cylinder Body is divided into closed the first cavity and the second cavity, and inlet and outlet is all provided on the first cavity and the second cavity;Described By solenoid valve and the outlet in the displacement liquid circuit, the outlet of first cavity passes through solenoid valve for the import of one cavity It is connected with the second entrance of the blood filter;The second outlet that the entrance of second cavity passes through solenoid valve and the blood filter Connection, the outlet of second cavity is in communication with the outside by solenoid valve.
Further, the outlet of dialyzate supply switching circuit entering by ultrafiltrate pump and net filter and blood circuit Mouth is connected and connected with the first entrance of the blood filter.
Further, the waste liquid discharge circuit includes waste drains pump and the first check valve, and the entrance of the waste drains pump passes through First check valve is connected with the second outlet of the blood filter, and the outlet of the waste drains pump is in communication with the outside.
Further, the displacement liquid circuit includes the first liquid pump, the second liquid pump, the 3rd liquid pump and reverse osmosis water pump, described First liquid pump, the second liquid pump, the entrance of the 3rd liquid pump and reverse osmosis water pump connect corresponding single liquid, first liquid respectively The outlet of pump, the second liquid pump, the 3rd liquid pump and reverse osmosis water pump is connected with the entrance of first cavity.
Further, the blood circuit includes first pressure monitor, the 4th liquid pump, anti-coagulants injection device, second Pressure monitor, mixer, the 3rd pressure monitor, leve monitor and bubble choked flow folder, the artery of human body pass sequentially through institute State the first of first pressure monitor, the 4th liquid pump, anti-coagulants injection device, second pressure monitor, mixer and blood filter Entrance connects, and it is gentle that the first outlet of the blood filter connected with the entrance passes sequentially through the 3rd pressure monitor, leve monitor Bubble choked flow folder is connected with the vein of human body.
Further, it is serially connected with to prevent liquid from flowing back to the second single of the second cavity in the outlet of second cavity To valve.
Further, the cylinder body is equipped with for the temperature control system of fluid temperature in master cylinder body.
Implement the utility model, have the advantages that:
1st, the utility model sets the first conductive detection device respectively by the second entrance and second outlet in blood filter With the second conductive detection device, to detect the electrical conductivity of the second entrance of the blood filter and second outlet respectively, and pass through meter Solute removal state can be monitored in real time, it can be achieved that being monitored in real time to the concentration for removing solute by calculating, and be conducive to adjustment in time and controlled Treatment scheme.And the concentration of concentration electrolyte A liquid and B liquid need not be changed in real-time monitoring process, solved existing online Monitoring toxin removing must change the concentration of concentrate dialysate to monitor the change of dialyzate conductivity, greatly ensure that treatment Stability and security, improve the effect for the treatment of.
2nd, the utility model uses multichannel supply loop alternately to supply dialyzate/displacement liquid, at work, one for blood filter When kind supply loop supplies dialyzate/displacement liquid feed flow for blood filter, which does not connect with displacement liquid circuit.This When, another way supply loop and displacement liquid circuit communication make displacement liquid circuit start to prepare dialyzate/displacement liquid and flow into supply It is stored in circuit, when dialyzate/displacement liquid in other supply loops has been used up, can switch in time and alternately be filtered for blood Device carries out feed flow, and whole process changes liquid without shutting down, guarantees dialyzate/displacement liquid without interruption so that fluid flow and pressure Power is stablized, stable and reliable in work, and the blood pressure stabilization of patient, dramatically reduces headache, Nausea and vomiting, extremely effective during treatment Improve the effect for the treatment of.
3rd, the utility model supply loop using reserve type dialyzate/displacement liquid feed flow Supply Structure, supply it is saturating Concentration, temperature and the osmotic pressure of analysis liquid/displacement liquid will not be influenced be subject to flow rate of liquid speed, it can be achieved that dialyzate/displacement liquid Flow velocity it is linear adjustable, with meet at any time treatment in flow rate of liquid speed adjust needs, it is easy to use and reliable and stable.Solution Determined it is existing by displacement liquid circuit directly supplied caused by need by computer system in fixed ratio rotating speed control A liquid The rotation of pump, B liquid pumps and reverse osmosis water liquid pump, can be only achieved it is accurate with liquid and if three liquid pumps rotating speed slightly it is small partially It is poor or asynchronous, it will cause the strength of fluid prepared very big offset occurs, seriously affect effect or even the patient for the treatment of The problem of life security.
4th, the utility model can adjust the dialyzate/put for flowing into and being mixed in blood circuit with blood by adjusting ultrafiltrate pump The amount of liquid is changed, to realize the control to ultrasiltrated rate, ultrafiltration pressure and ultrafiltration volume etc., to meet to being wanted in treatment to ultrafiltration parameter It asks, has the characteristics that versatility is good and easy to use.
5th, the utility model installs waste drains pump to realize to waste liquid and dialyzate/put at the second outlet of blood filter The control of flow quantity is changed, without using gravity and pressure sensor and electronic equilibrium weighing device, greatly simplifies the knot of equipment Structure, and easy to operate, work more security reliability.
Description of the drawings
It in order to illustrate the embodiment of the utility model or the technical proposal in the existing technology more clearly, below will be to embodiment Or attached drawing needed to be used in the description of the prior art is briefly described, it should be apparent that, the accompanying drawings in the following description is only It is some embodiments of the utility model, for those of ordinary skill in the art, in the premise not made the creative labor Under, it can also be obtained according to these attached drawings other attached drawings.
Fig. 1 is the structure diagram of the Solute removal monitoring system of the utility model blood cleaning equipment.
Specific embodiment
The following is a combination of the drawings in the embodiments of the present utility model, and the technical scheme in the embodiment of the utility model is carried out It clearly and completely describes, it is clear that the described embodiments are only a part of the embodiments of the utility model rather than whole Embodiment.Based on the embodiment in the utility model, those of ordinary skill in the art are without creative efforts All other embodiments obtained shall fall within the protection scope of the present invention.
Embodiment
With reference to Fig. 1, the present embodiment is related to the Solute removal monitoring system of blood cleaning equipment, is filtered including blood circuit 1, blood Device 2, displacement liquid circuit 3, dialyzate supply switching circuit 4 and waste liquid discharge circuit 5, the first entrance of the blood filter 2 pass through Blood circuit 1 is connected with the outlet of dialyzate supply switching circuit 4 and the artery of human body, the blood filter 2 connected with the entrance First outlet connected by blood circuit 1 with the vein of human body;The second entrance of the blood filter 2 is cut by dialyzate supply The outlet on road 4 and displacement liquid circuit 3 is gained, the second outlet of the blood filter 2 connected with the entrance is supplied by dialyzate Switching circuit 4 and waste liquid discharge circuit discharge;The dialyzate supply switching circuit 4 includes at least two-way supply loop 41, each road supply loop 41 is alternately connected or closed with the second entrance of blood filter 2, and each road supply loop 41 alternating and blood The second outlet connection of filter 2 is closed, and is formed and is switched structure without interruption;Dialyzate supply switching circuit 4 with it is described The first conductive detection device 9, the dialyzate supply switching circuit 4 and the blood are serially connected between the second entrance of blood filter 2 The second conductive detection device 10 is serially connected between the second outlet of filter 2.
The structure uses multichannel supply loop 41 alternately to supply dialyzate/displacement liquid for blood filter 2, at work, a kind of When supply loop 41 supplies dialyzate/displacement liquid feed flow for blood filter 2, which does not connect with displacement liquid circuit 3. At this point, another way supply loop 41 is connected with displacement liquid circuit 3, displacement liquid circuit 3 is made to start to prepare dialyzate/displacement liquid cocurrent Enter and stored in supply loop 41, when dialyzate/displacement liquid in other supply loops 41 has been used up, can be switched in time And feed flow alternately is carried out for blood filter 2, whole process changes liquid without shutting down, and guarantees dialyzate/displacement liquid without interruption so that Fluid flow and pressure stability, stable and reliable in work, the blood pressure stabilization of patient, dramatically reduces headache, nausea, vomits during treatment It spits, extremely effective improves the effect for the treatment of.
Since the supply loop 41 is using the Supply Structure of dialyzate/displacement liquid feed flow of reserve type, the dialyzate of supply/ Concentration, temperature and the osmotic pressure of displacement liquid will not be influenced be subject to flow rate of liquid speed, it can be achieved that dialyzate/displacement flow velocity It is linear adjustable, it is easy to use and reliable and stable to meet the needs adjusted in treatment to flow rate of liquid speed at any time.It solves existing Have by displacement liquid circuit 3 directly supplied caused by need to control A liquid pumps, B in fixed ratio rotating speed by computer system The rotation of liquid pump and reverse osmosis water liquid pump, can be only achieved accurately with liquid and if the rotating speed slightly little deviation of three liquid pumps or It is asynchronous, it will cause the strength of fluid prepared that very big offset occurs, seriously affect the effect for the treatment of or even the life of patient The problem of safe.
Since the concentration-temperature and osmotic pressure of dialyzate/displacement liquid of supply will not be influenced be subject to flow rate of liquid speed, Keep higher stability.Therefore, described in can respectively being detected by the first conductive detection device 9 and the second conductive detection device 10 The second entrance of blood filter 2 and the electrical conductivity of second outlet;
Dialyzate ion clearance rate is obtained according to expression formula
Wherein, Cdi is the average value (mS/cm) of the electric conductivity value of the second entrance of the blood filter 2, and Cdo filters for the blood The average value (mS/cm) of the electric conductivity value of the second outlet of device 2, Cdimax are the maximum measured at Cdi, and Cdomin is at Cdo The minimum value measured, D are dialyzate ion clearance rate (ml/min);
It calculates urea and removes kinetic model
Wherein, V is that the effective of patient removes volume (ml), and T is dialysis time (min).
By setting the first conductive detection device 9 and the second conductance respectively in the second entrance and second outlet of blood filter 2 To detect the electrical conductivity of the second entrance of the blood filter 2 and second outlet respectively, it is clear can to monitor solute in real time for detection device 10 Except state, realize and the concentration for removing solute is monitored over the course for the treatment of in real time, be conducive to adjust therapeutic scheme in time.And And the concentration of concentration electrolyte A liquid and B liquid need not be changed in real-time monitoring process, solve existing on-line monitoring Dusuqing The change of dialyzate conductivity is monitored except the concentration that must change concentrate dialysate, greatly ensure that treatment stability and Security improves the effect for the treatment of.
The supply loop 41 includes cylinder body 411 and solenoid valve 412, the cylinder body 411 be internally provided with elastic interlayer and incite somebody to action Cylinder body 411 is divided into closed the first cavity 413 and the second cavity 414, is all provided on the first cavity 413 and the second cavity 414 Inlet and outlet;The import of first cavity 413 passes through solenoid valve 412 and the outlet in the displacement liquid circuit 3, institute The outlet for stating the first cavity 413 is connected by solenoid valve 412 with the second entrance 23 of the blood filter 2;Second cavity 414 Entrance connected by solenoid valve 412 with the second outlet 24 of the blood filter 2, the outlet of second cavity 414 passes through electricity Magnet valve 412 is in communication with the outside.
First cavity 413 is used to store dialyzate/displacement liquid of concentration needed for the proportioning completion of displacement liquid circuit 3, the second chamber The waste liquid that body 414 flows out for storage from the second outlet 24 of blood filter 2.It is made in displacement liquid circuit 3 into the first cavity 413 During standby dialyzate/displacement liquid, liquid in the first cavity 413 by spatial spread of the elastic interlayer into the second cavity 414 and The waste liquid in the second cavity 414 is squeezed, so as to play the role of that the waste liquid in the second cavity 414 being cleared up in advance.And During first cavity 413 supplies dialyzate/displacement liquid to blood filter 2, the is constantly flowed back to from the second outlet 24 of blood filter 2 Spatial spread into the first cavity 413 of waste liquid in two cavitys 414 and squeeze dialyzate/displacement liquid in the first cavity 413, There is provided extruding force makes dialyzate/displacement liquid steadily be flowed, simple in structure, reduces the use of liquid pump and other auxiliary components Amount, manufacture is at low cost and can reduce failure rate.
The outlet of the dialyzate supply switching circuit 4 is connected by ultrafiltrate pump 6 and net filter 7 and the entrance of blood circuit 1 Lead to and connected with the first entrance 21 of the blood filter 2.By adjust ultrafiltrate pump 6 can adjust flow into blood circuit 1 in blood The amount of dialyzate/displacement liquid of liquid mixing, to realize the control to ultrasiltrated rate, ultrafiltration pressure and ultrafiltration volume etc., to meet to controlling To the requirement of ultrafiltration parameter in treatment, have the characteristics that versatility is good and easy to use.It is returned by the way that ultrafiltrate pump 6 is adjustable into blood The flow speed scope of dialyzate/displacement liquid in road 1 is 50-500ml/ minute, be conducive to make preposition displacement liquid blood filter or after The selection for the methods of putting the filter of displacement liquid blood.
Waste liquid discharge circuit 5 includes 51 and first check valve 52 of waste drains pump, and the entrance of the waste drains pump 51 passes through the One check valve 52 is connected with the second outlet 24 of the blood filter 2, and the outlet of the waste drains pump 51 is in communication with the outside.In blood filter Waste drains pump 51 is installed to realize the control to waste liquid and dialyzate/displacement flow quantity, without using weight at 2 second outlet 24 Power and pressure sensor and electronic equilibrium weighing device greatly simplifie the structure of equipment, and easy to operate, and work is safer Reliability.When flow speed scope by the adjustable waste liquid for pumping out the external world of waste drains pump 51 is 0-2000ml/ small, the ultrafiltration The flow speed of the waste liquid gone out is adjustable at any time, and convenient for Clinical practice, the liquid that ultrafiltration goes out is packed into graduated ultrafiltrate vessel In, how much the amount of liquid that ultrafiltration goes out can know that the liquid measure that ultrafiltration goes out should be the dehydrating amount of patient in real time.
The displacement liquid circuit 3 includes the first liquid pump 31, the second liquid pump 32, the 3rd liquid pump 33 and reverse osmosis water pump 34, described First liquid pump 31, the second liquid pump 32, the entrance of the 3rd liquid pump 33 and reverse osmosis water pump 34 connect corresponding single liquid respectively, described First liquid pump 31, the second liquid pump 32, the 3rd liquid pump 33 and the outlet of reverse osmosis water pump 34 connect with the entrance of first cavity 413 It is logical.Control system controls the rotating speed ratio of the first liquid pump 31, the second liquid pump 32, the 3rd liquid pump 33 and reverse osmosis water pump 34, makes A respectively Liquid, B liquid, S liquid are mixed by firm discharge with reverse osmosis water and match into required concentration.
The blood circuit 1 includes first pressure monitor 11, the 4th liquid pump 12, anti-coagulants injection device 13, second and presses Power monitor 14, mixer 15, the 3rd pressure monitor 16, leve monitor 17 and bubble choked flow folder 18, the artery of human body according to It is secondary to pass through the first pressure monitor 11, the 4th liquid pump 12, anti-coagulants injection device 13, second pressure monitor 14, mixing Device 15 is connected with the first entrance 21 of blood filter 2, and the first outlet 22 of the blood filter 2 connected with the entrance passes sequentially through the 3rd pressure Power monitor 16, leve monitor 17 and bubble choked flow folder 18 are connected with the vein of human body.
The artery of patient by arterial puncture needle successively with the first pressure monitor 11, the 4th liquid pump 12, anti-coagulants Injection device 13, second pressure monitor 14 and mixer 15 are connected with the first entrance 21 of blood filter 2;Blood flows into artery After puncture needle, after anti-coagulants injection device 13 injects anti-coagulants, inputted by the 4th liquid pump 12 into mixer 15.In mixer Blood filter 2 is conveyed by the first entrance 21 of blood filter 2 after blood is mixed with dialyzate/displacement liquid in 15.It is wherein toxic Dialyzate/displacement liquid of element is filtered out, and clean blood is exported from the first outlet 22 of blood filter 2, by passing sequentially through the 3rd Pressure monitor 16, leve monitor 17 and bubble choked flow folder 18 are connected with the vein of human body and flowed in the vein of human body, from And defeated time in patient body.
The waste liquid of discharge line countercurrently enters the second cavity 414 in order to prevent, is gone here and there in the outlet of second cavity 414 It is connected to prevent that liquid from flowing back the second check valve 8 to the second cavity 414.
In order to ensure that the temperature value that the dialyzate/displacement liquid for flowing into 2 second entrance 23 of blood filter mixes reaches requirement and constant temperature, The cylinder body 411 is equipped with to control the temperature control system of fluid temperature in cylinder body 411.
The present embodiment also provides a kind of Solute removal monitoring method for blood cleaning equipment, comprises the following steps:
1) every the time of setting, institute is detected by the first conductive detection device 9 and the second conductive detection device 10 respectively State the second entrance of blood filter 2 and the electrical conductivity of second outlet;
2) dialyzate ion clearance rate is obtained according to expression formula
Wherein, Cdi is the average value (mS/cm) of the electric conductivity value of the second entrance of the blood filter 2, and Cdo filters for the blood The average value (mS/cm) of the electric conductivity value of the second outlet of device 2, Cdimax are the maximum measured at Cdi, and Cdomin is at Cdo The minimum value measured, D are dialyzate ion clearance rate (ml/min);As preference, it can respectively pass through the first conductance as needed 9 and second conductive detection device 10 of detection device carries out once-through operation after collecting 3-5 data, acquisition Cdi, Cdo, Cdimax, Above formula is substituted into after three values of Cdomin to be calculated.And according to counted clearance rate, the dynamic of dynamic monitoring is obtained by following formula Mechanical model.By real-time collecting conductance data, when there is changing larger abnormal data into can find that system is abnormal in time Working condition to adjust in time or halt system works, ensures the therapeutic effect and life security of patient.
3) calculate urea and remove kinetic model
Wherein, V is that the effective of patient removes volume (ml), and T is dialysis time (min).
Corresponding kinetic model can be calculated by above formula, table 2 is to calculate to remove index per 15min by upper formula, Gradually cumulative Dt/v values, when the time reaching 240min, Dt/v 1.22.Wherein table 1 was connected with 15min the and 30min moment Continuous Cdi, Cdo, Cdimax and Cdomin measured, and substitute into calculating formula (2) Dt/v.
Table 1:The Dt/v of 15min and 30min:
Table 2:Per the integration of 15min counted Dt/v and Dt/v:
Therefore, according to this Dt/v model, per data are collected once at regular intervals, can synchronously it be drawn and shown by calculating Show that urea kinetic tendency chart is as shown below.During clinical Real Time Observation Solute removal effect, when dialysis treatment 4 is small Dt/v is effective more than 1.2, and the factor for influencing Solute removal effect should be checked less than 1.2.
The operation principle of the utility model:
The artery of patient by arterial puncture needle successively with the first pressure monitor 11, the 4th liquid pump 12, anti-coagulants Injection device 13, second pressure monitor 14 and mixer 15 are connected with the first entrance 21 of blood filter 2;Blood flows into artery After puncture needle, after anti-coagulants injection device 13 injects anti-coagulants, inputted by the 4th liquid pump 12 into mixer 15.In mixer Blood filter 2 is conveyed by the first entrance 21 of blood filter 2 after blood is mixed with dialyzate/displacement liquid in 15.It is wherein toxic Dialyzate/displacement liquid of element is filtered out, and clean blood is exported from the first outlet 22 of blood filter 2, by passing sequentially through the 3rd Pressure monitor 16, leve monitor 17 and bubble choked flow folder 18 are connected with the vein of human body and flowed in the vein of human body, from And defeated time in patient body.
Dialyzate/displacement liquid through putting the extraction of ultrafiltrate pump 6 flows through net filter 7 and is input in mixer 15, in mixer 15 Middle blood by the first entrance 21 of blood filter 2 is transported to blood filter 2 after being mixed with dialyzate/displacement liquid, the dialysis containing toxin Liquid/displacement liquid becomes waste liquid and is drawn to by the second outlet 24 of blood filter 2 in the second cavity 414, is installed on blood filter 2 Second outlet 24 pipeline on waste drains pump 51 extract out liquid can be loaded on ultrafiltrate vessel in or be connected on sewer pipe directly It excludes, dehydrating amount when this liquid is treated for the filter of patient's blood.
During dialyzate/displacement liquid is supplied for the second entrance 23 of blood filter 2, first by the first supply loop 41 In the first cavity 413 of cylinder body 411 supplied, meanwhile, displacement liquid circuit 3 prepares dialyzate/displacement liquid and flows into second In the cylinder of supply loop 41.When dialyzate/displacement liquid in the first cavity 413 runs out, the cylinder body of the second supply loop 41 The solenoid valve 412 of the outlet of 411 the first cavity 413 is opened, so as to tangentially be supplied to the second supply loop 41 for blood filter 2 Analyse liquid/displacement liquid.The solenoid valve 412 of the outlet of the first cavity 413 of the cylinder body 411 of the first supply loop 41 is closed simultaneously, and And the solenoid valve 412 of its entrance is opened, displacement liquid circuit 3 prepares dialyzate/displacement liquid and flows into the cylinder of the first supply loop 41 It is interior, so as to fulfill the purpose of dialyzate/displacement liquid is alternately supplied for blood filter 2.And every the time of setting, pass through the first electricity It leads 9 and second conductive detection device 10 of detection device and detects the second entrance of the blood filter 2 and the conductance of second outlet respectively The data detected are transmitted to controller and calculated by rate, and are passed through display real-time display and gone out corresponding kinetic simulation figure, To observe the elimination effect of urea constantly.
Above disclosed is only a kind of the utility model preferred embodiment, cannot limit this practicality with this certainly New interest field, therefore the equivalent variations made according to the utility model claims, still belong to what the utility model was covered Scope.

Claims (8)

1. a kind of Solute removal monitoring system of blood cleaning equipment, it is characterised in that:Including blood circuit, blood filter, displacement Liquid circuit, dialyzate supply switching circuit and waste liquid discharge circuit, the first entrance of the blood filter by blood circuit with thoroughly It analyses the outlet of liquid supply switching circuit and the artery connection of human body, the first outlet of the blood filter connected with the entrance passes through blood Liquid circuit is connected with the vein of human body;The second entrance of the blood filter supplies switching circuit and displacement liquid circuit by dialyzate Outlet, the second outlet of the blood filter connected with the entrance passes through that dialyzate supplies switching circuit and waste liquid discharges circuit It discharges;The dialyzate supply switching circuit includes at least two-way supply loop, each road supply loop alternating and blood filter Second entrance connection or close, and each road supply loop alternately connect or closes with the second outlet of blood filter, formation switch Structure without interruption;The inspection of the first conductance is serially connected between the dialyzate supply switching circuit and the second entrance of the blood filter Device is surveyed, the second Conductivity detection dress is serially connected between the dialyzate supply switching circuit and the second outlet of the blood filter It puts.
2. a kind of Solute removal monitoring system of blood cleaning equipment according to claim 1, it is characterised in that:The confession Answering circuit includes cylinder body and solenoid valve, the cylinder interior be equipped with elastic interlayer and by cylinder body be divided into the first closed cavity and Inlet and outlet is all provided on second cavity, the first cavity and the second cavity;The import of first cavity by solenoid valve with The outlet in the displacement liquid circuit, the outlet of first cavity are connected by the second entrance of solenoid valve and the blood filter It is logical;The entrance of second cavity is connected by solenoid valve with the second outlet of the blood filter, the outlet of second cavity It is in communication with the outside by solenoid valve.
3. a kind of Solute removal monitoring system of blood cleaning equipment according to claim 1, it is characterised in that:It is described The outlet of analysis liquid supply switching circuit connected by ultrafiltrate pump and net filter with the entrance of blood circuit and with the blood filter First entrance connects.
4. a kind of Solute removal monitoring system of blood cleaning equipment according to claim 1, it is characterised in that:It is described useless Liquid discharge circuit includes waste drains pump and the first check valve, and the entrance of the waste drains pump passes through the first check valve and the blood filter Second outlet connects, and the outlet of the waste drains pump is in communication with the outside.
5. a kind of Solute removal monitoring system of blood cleaning equipment according to claim 2, it is characterised in that:It is described to put Changing liquid circuit includes the first liquid pump, the second liquid pump, the 3rd liquid pump and reverse osmosis water pump, first liquid pump, the second liquid pump, the 3rd liquid The entrance of pump and reverse osmosis water pump connects corresponding single liquid, first liquid pump, the second liquid pump, the 3rd liquid pump and reverse osmosis respectively The outlet of water pump is connected with the entrance of first cavity.
6. a kind of Solute removal monitoring system of blood cleaning equipment according to any one of claims 1 to 5, feature exist In:The blood circuit includes first pressure monitor, the 4th liquid pump, anti-coagulants injection device, second pressure monitor, mixing Device, the 3rd pressure monitor, leve monitor and bubble choked flow folder, the artery of human body pass sequentially through the first pressure monitoring Device, the 4th liquid pump, anti-coagulants injection device, second pressure monitor, mixer are connected with the first entrance of blood filter, are entered with this The first outlet of the blood filter of mouthful connection passes sequentially through the 3rd pressure monitor, leve monitor and bubble choked flow folder and human body Vein connects.
7. a kind of Solute removal monitoring system of blood cleaning equipment according to claim 2, it is characterised in that:Described It is serially connected with to prevent that liquid from flowing back the second check valve to the second cavity in the outlet of two cavitys.
8. a kind of Solute removal monitoring system of blood cleaning equipment according to claim 2, it is characterised in that:The cylinder Body is equipped with for the temperature control system of fluid temperature in master cylinder body.
CN201720177006.5U 2017-02-24 2017-02-24 A kind of Solute removal monitoring system of blood cleaning equipment Active CN207429440U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106938063A (en) * 2017-02-24 2017-07-11 暨南大学 The Solute removal monitoring system and its method of a kind of blood cleaning equipment

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106938063A (en) * 2017-02-24 2017-07-11 暨南大学 The Solute removal monitoring system and its method of a kind of blood cleaning equipment

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