CN106730085B - Liquid supply bag and replacement liquid preparation system comprising same - Google Patents
Liquid supply bag and replacement liquid preparation system comprising same Download PDFInfo
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- CN106730085B CN106730085B CN201611217987.8A CN201611217987A CN106730085B CN 106730085 B CN106730085 B CN 106730085B CN 201611217987 A CN201611217987 A CN 201611217987A CN 106730085 B CN106730085 B CN 106730085B
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- 239000007788 liquid Substances 0.000 title claims abstract description 206
- 238000002360 preparation method Methods 0.000 title abstract description 15
- 239000008280 blood Substances 0.000 claims abstract description 64
- 210000004369 blood Anatomy 0.000 claims abstract description 64
- 239000012530 fluid Substances 0.000 claims abstract description 49
- 239000002699 waste material Substances 0.000 claims abstract description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 23
- 238000001223 reverse osmosis Methods 0.000 claims abstract description 21
- 239000000843 powder Substances 0.000 claims abstract description 8
- 238000007789 sealing Methods 0.000 claims abstract description 7
- 239000000463 material Substances 0.000 claims abstract description 4
- 239000000243 solution Substances 0.000 claims description 56
- 239000003146 anticoagulant agent Substances 0.000 claims description 9
- 229940127219 anticoagulant drug Drugs 0.000 claims description 9
- 239000007924 injection Substances 0.000 claims description 8
- 238000002347 injection Methods 0.000 claims description 8
- 210000001367 artery Anatomy 0.000 claims description 7
- 210000003462 vein Anatomy 0.000 claims description 7
- 230000000903 blocking effect Effects 0.000 claims description 6
- 238000000502 dialysis Methods 0.000 claims description 2
- 230000036770 blood supply Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 238000000746 purification Methods 0.000 description 5
- 206010019233 Headaches Diseases 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 238000001631 haemodialysis Methods 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 230000000322 hemodialysis Effects 0.000 description 2
- 238000002615 hemofiltration Methods 0.000 description 2
- 239000012510 hollow fiber Substances 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 239000002253 acid Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000000385 dialysis solution Substances 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 238000002637 fluid replacement therapy Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1643—Constructional aspects thereof with weighing of fresh and used dialysis fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
Abstract
The invention discloses a liquid supply bag, which comprises a bag body made of flexible materials, wherein a liquid port for flowing liquid into and out of the bag body and a gas port for flowing air into and out of the bag body are formed in the bag body; the liquid port is internally provided with a liquid pipe which is connected with the bag body in a sealing way; the tail end of the liquid pipe extends into the inner bottom of the bag body, and the bag body is internally provided with a corresponding amount of concentrated liquid or dry powder according to the volume of the bag body and the concentration of the solution required; and vacuumizing the bag body, and injecting reverse osmosis water into the bag body through the liquid pipe when the solution is required to be prepared. Also provided is a replacement fluid preparation system comprising the fluid supply bag, a blood circuit, a blood filter, a replacement fluid circuit, a dialysate supply switching circuit and a waste fluid discharge circuit. The invention has the advantages of automatic adjustment, high control precision, wide application range, convenient use, low cost, stability and reliability.
Description
Technical Field
The invention relates to the technical field of blood purification, in particular to a liquid supply bag and a replacement liquid preparation system formed by the same.
Background
The blood purifying equipment is a therapeutic device which passes blood through the central part of a hollow fiber semipermeable membrane capable of passing medium and small molecular substances, passes prepared isotonic liquid (such as dialyzate, replacement liquid, peritoneal dialysis liquid, balance liquid and the like), passes through the outer side of the hollow fiber membrane, removes a large amount of water, medium and small molecular toxins in a patient body under the action of osmotic pressure and transmembrane pressure through the principles of dispersing, convection, ultrafiltration and the like, and maintains the balance of water, electrolyte and alkali acid in the body so as to achieve blood purification. Current blood purification devices are classified into hemodialysis devices (which are also classified into hemodialysis machines and hemodiafiltration machines) and continuous blood purification devices (CRRT machines).
The isotonic liquid preparation of the currently commonly used blood purification devices has the following disadvantages: 1) The isotonic liquid is required to rotate the A liquid pump, the B liquid pump and the reverse osmosis water liquid pump according to fixed proportion rotation speed by a computer system so as to achieve accurate liquid preparation. If the rotation speeds of the three liquid pumps are slightly deviated or are not synchronous, the prepared liquid concentration can be greatly deviated, the treatment effect is seriously affected, and even the life safety of patients is ensured. And because the preparation can only adopt a fixed flow rate for proportioning, the preparation speed and flow rate cannot be linearly regulated; 2) When the hemofiltration treatment is carried out, an electronic balance scale and all the replaced liquid are contained on one side of the scale, a clean replacement liquid bag is hung on the other side of the scale so as to balance the liquid inlet and outlet amount, the liquid replacement bag is stopped in the hemofiltration process, the treatment time is influenced, and the process is required to be manually operated, and has complicated operation and easy operation errors; 3) Two electronic scales must be adopted, one of which is used for weighing the replacement liquid, the other is used for weighing the replacement liquid, and the computer balances the electronic scales through the gravity and the pressure sensor, so that the two electronic scales must be regularly positive, otherwise, the treatment effect is affected; 4) The equipment has complex structure, more parts, easy failure, difficult maintenance and detection and poor reliability and stability.
Disclosure of Invention
The invention aims to solve the defects and provide the liquid supply bag and the replacement liquid preparation system formed by the liquid supply bag, which have the advantages of automatic adjustment, high control precision, wide application range, convenient use, low cost, stability and reliability.
The aim of the invention can be achieved by adopting the following technical scheme:
a liquid supply bag and a replacement liquid preparation system formed by the same comprise a bag body made of flexible materials, wherein a liquid port for liquid to flow into and out of the bag body and a gas port for air to flow into and out of the bag body are formed in the bag body; the liquid port is internally provided with a liquid pipe which is connected with the bag body in a sealing way; the tail end of the liquid pipe extends into the inner bottom of the bag body, and the bag body is internally provided with a corresponding amount of concentrated liquid or dry powder according to the volume of the bag body and the concentration of the solution required; and vacuumizing the bag body, and injecting reverse osmosis water into the bag body through the liquid pipe when the solution is required to be prepared.
Further, an air pipe is arranged on the air port and is in sealing connection with the air port.
As a preferable scheme, the liquid pipe and the gas pipe are connected into a whole through a connecting block.
As a preferable scheme, the outer part of the bag body is sleeved with a frame body for generating stretching deformation of the bag body.
As a preferable scheme, the inner wall of the frame body is provided with a groove, and when reverse osmosis water enters the bag body through the liquid pipe, the outer surface of the bag body is contacted with the inner surface of the frame body so as to squeeze air between the bag body and the frame body into the groove.
As a preferable scheme, the wall of the frame body is provided with a through hole, and when reverse osmosis water enters the bag body through the liquid pipe, the outer surface of the bag body is contacted with the inner surface of the frame body, so that air between the bag body and the frame body is extruded to the outside of the frame body through the through hole.
A replacement fluid preparation system using a fluid supply bag, comprising the fluid supply bag, a blood circuit, a blood filter, a replacement fluid circuit, a dialysis fluid supply switching circuit and a waste fluid discharge circuit, wherein the fluid supply bag is communicated with an inlet of the replacement fluid circuit; the first inlet of the blood filter is communicated with the outlet of the dialysate supply switching loop and the artery of the human body through the blood loop, and the first outlet of the blood filter communicated with the inlet is communicated with the vein of the human body through the blood loop; the second inlet of the blood filter is communicated with the outlet of the replacement liquid loop through the dialysate supply switching loop, and the second outlet of the blood filter communicated with the inlet is discharged outwards through the dialysate supply switching loop and the waste liquid discharge loop; the dialysate supply switching loop comprises at least two supply loops, wherein each supply loop is alternately communicated with or closed to a second inlet of the blood filter, and each supply loop is alternately communicated with or closed to a second outlet of the blood filter to form a switching continuous supply structure;
further, the number of the liquid supply bags is three, and the liquid supply bags are filled with reverse osmosis water to prepare three solutions; the replacement liquid loop comprises a first liquid pump, a second liquid pump, a third liquid pump, a mixer and a clean filter, wherein inlets of the first liquid pump, the second liquid pump and the third liquid pump are respectively communicated with liquid pipes on the three liquid supply bags; the outlets of the first liquid pump, the second liquid pump and the third liquid pump are communicated with the inlet of the mixer to mix the three solutions; the outlet of the mixer communicates with the inlet of the dialysate supply switching loop through a clean filter.
Further, the dialysate supply switching loop comprises a first electronic scale and a second electronic scale, wherein a replacement liquid storage bag and a waste liquid storage bag are weighed on the first electronic scale and the second electronic scale, an inlet of the replacement liquid storage bag is communicated with an outlet of the mixer through an electromagnetic valve, and an outlet of the replacement liquid storage bag is communicated with a first inlet and a second inlet of the blood filter through the electromagnetic valve to form a two-way input supply switching structure; the inlet of the waste liquid storage bag is communicated with the second outlet of the blood filter through an electromagnetic valve, and the outlet of the waste liquid storage bag is communicated with the outside through the electromagnetic valve to form a two-way output supply switching structure.
Further, the blood circuit comprises a first pressure monitor, a liquid pump, an anticoagulant injection device, a second pressure monitor, a second mixer, a liquid level monitor and a bubble blocking clamp, an artery of a human body is communicated with a first inlet of a blood filter through the first pressure monitor, the liquid pump, the anticoagulant injection device and the mixer, and a first outlet of the blood filter communicated with the inlet is communicated with a vein of the human body through the second pressure monitor, the liquid level monitor and the bubble blocking clamp.
Further, the waste liquid discharge loop comprises a liquid pump and a waste liquid bag, an inlet of the liquid pump is communicated with the second outlet of the blood filter, and an outlet of the liquid pump is communicated with the waste liquid bag.
The implementation of the invention has the following beneficial effects:
1. the volume of the bag body is designed to be quantitative, and the weight of the concentrated solution or the dry powder of the corresponding type is calculated according to the concentration of the required solution and is placed in the bag body in advance. And carrying out storage and transportation in a vacuumizing mode. When the solution of the corresponding type is needed, the solution concentration meeting the requirements can be rapidly prepared by filling the reverse osmosis water into the liquid pipe, and then the solution flows out through the liquid pipe to supply the solution, so that the preparation is simple, convenient and accurate, the prepared liquid concentration is not greatly deviated, the treatment effect is seriously affected, and even the problem of life safety of a patient is solved.
2. When reverse osmosis water is injected into the bag body, under the limiting effect of the frame body, the bag body can only expand to the volume of the contact between the outer wall of the bag body and the inner wall of the frame body, at the moment, the volume of the bag body is equal to the volume of the frame body, the condition that the volume of the bag body cannot exceed the required size due to stretching is guaranteed, and further the concentration of the proportioning solution of the bag body is guaranteed to meet the required requirement. The size of the inner part of the frame body is designed and determined according to the volume design of the bag body and the concentration of the solution. If the volume of the bag exceeds the set size, the concentration of the prepared solution is caused to be too low to the required value, and when the volume of the bag is smaller than the set size, the concentration of the prepared solution is caused to exceed the required value.
3. In the invention, part of air between the bag body and the frame body is extruded into the groove for storage in the process of expanding the bag body, so that the outer surface of the bag body can be contacted with the inner wall of the frame body, and the volume of the bag body is ensured to be equal to a set target value. The problem of in the in-process bag body inflation between bag body and the framework can't outwards flow and be sealed between bag body and the framework from the upper end of framework to lead to the bag body to can not expand to the volume and the inside volume size of framework equal and produce the solution concentration of preparing in the bag body and be higher is solved.
4. Before the three liquid supply bags are connected with the inlet of the replacement liquid loop, reverse osmosis water is filled into the bag body to prepare three solutions with corresponding concentrations, and the three solutions are mixed in the replacement loop to prepare the dialysate and are supplied to the dialysate supply switching loop. Because the solution proportion of the liquid supply bag is simple, convenient and accurate, a large number of liquid supply bags meeting the concentration requirement can be rapidly proportioned to replace the used liquid supply bags at any time, the time for changing the bags is greatly reduced, and the working efficiency is improved.
5. After the solutions of the three liquid supply bags are prepared into the dialysate in the replacement liquid loop, the dialysate is subjected to one of the supply loops and is stored in the replacement liquid storage bag. When the solution in the solution supplying bag is used up, the prepared new supplying bag can be quickly replaced for continuous supply, the condition that the supply of the solution is interrupted can be prevented, and the treatment effect is improved. When the dialysate in the replacement fluid storage bag of the supply loop is used up, the control device controls the working state of the corresponding electromagnetic valve to enable the replacement fluid loop to be communicated with the other supply loop so that the dialysate flows into the replacement fluid storage bag of the other supply loop, the whole process does not need to stop the fluid replacement, the continuous supply of the dialysate is ensured, the fluid flow and the pressure are stable, the working is stable and reliable, the blood pressure of a patient is stable during treatment, headache, nausea and vomiting are greatly reduced, and the treatment effect is greatly improved.
Drawings
In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a cross-sectional view of a fluid supply bag of the present invention along a central axis;
FIG. 2 is a cross-sectional view of the frame of the liquid supply bag of embodiment 1 of the present invention;
FIG. 3 is a cross-sectional view of the frame of the liquid supply bag according to embodiment 2 of the present invention;
FIG. 4 is a schematic diagram of a replacement fluid dispensing system employing a fluid supply bag according to the present invention.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Examples
Referring to fig. 1, the present embodiment relates to a liquid supply bag and a replacement liquid preparation system constituted by the same, comprising a bag body 1 made of a flexible material, wherein a liquid port for liquid to flow into and out of the bag body 1 and a gas port for air to flow into and out of the bag body 1 are formed in the bag body 1; the liquid port is internally provided with a liquid pipe 2, and the liquid pipe 2 is connected with the bag body 1 in a sealing way; the tail end of the liquid pipe 2 extends into the inner bottom of the bag body 1, and a corresponding amount of concentrated solution or dry powder is filled in the bag body 1 according to the volume of the bag body 1 and the concentration of the solution required; and vacuumizing the bag body 1, and injecting reverse osmosis water into the bag body 1 through the liquid pipe 2 when a solution is required to be prepared. The bag body 1 with the structure is filled with concentrated solution or dry powder with required type and weight, and adopts an internal vacuumizing mode during transportation, so that the concentrated solution or dry powder can be prevented from being deteriorated due to contact with air, and the volume of the bag body 1 can be reduced so as to be convenient for folding and transportation.
The volume of the bag body 1 of the structure is designed to be quantitative, and the weight of the corresponding type of concentrated solution or dry powder is calculated according to the concentration of the required solution and is placed in the bag body 1 in advance. And carrying out storage and transportation in a vacuumizing mode. When the corresponding type of solution is needed, the solution concentration meeting the requirement can be rapidly prepared by filling the liquid pipe 2 with reverse osmosis water, and then the solution flows out through the liquid pipe 2 to supply the solution, so that the preparation is simple, convenient and accurate, the prepared liquid concentration is not greatly deviated, the treatment effect is seriously affected, and even the life safety of a patient is improved.
The air port is provided with an air pipe 3, and the air pipe 3 is in sealing connection with the air port. When vacuumizing, air in the bag body 1 is pumped out through the air pipe 3, and after reverse osmosis water is injected into the bag body 1 to prepare a required solution and the solution is supplied outwards through the liquid pipe 2, external air enters the bag body 1 through the air pipe 3, so that the liquid supply can be ensured to be carried out normally.
The liquid pipe 2 and the air pipe 3 are connected into a whole through a connecting block 4. The connecting block 4 is used for fixing the liquid pipe 2 and the air pipe 3 together, preventing the liquid pipe 2 and the air pipe 3 from swinging, and improving the connection stability among the liquid pipe 2, the air pipe 3 and the bag body 1.
The outer part of the bag body 1 is sleeved with a frame body 5 for generating stretching deformation of the bag body 1. When reverse osmosis water is injected into the bag body 1, under the limiting effect of the frame body 5, the bag body 1 can only expand to the volume of the contact between the outer wall of the bag body 1 and the inner wall of the frame body 5, at the moment, the volume of the bag body 1 is equal to the volume of the frame body 5, the condition that the volume of the bag body 1 exceeds the required size due to stretching is avoided, and the concentration of the proportioning solution of the bag body 1 is further ensured to meet the required requirement. The volume of the inside of the frame 5 is determined by the volume design of the bag 1 and the concentration of the solution. If the volume of the bag 1 exceeds the set size, the concentration of the prepared solution is caused to be too low to the required value, and if the volume of the bag 1 is smaller than the set size, the concentration of the prepared solution is caused to exceed the required value.
As shown in fig. 2, in order to prevent a portion of air between the bag body 1 and the frame body 5 from being able to flow out from the upper end of the frame body 5 during the expansion of the bag body 1, the air is sealed between the bag body 1 and the frame body 5, and the bag body 1 cannot be expanded to a volume equal to the internal volume of the frame body 5, so that the concentration of the solution prepared in the bag body 1 is high. The inner wall of the frame body 5 is provided with a groove 51, and when reverse osmosis water enters the bag body 1 through the liquid pipe 2, the outer surface of the bag body 1 is contacted with the inner surface of the frame body 5 to squeeze air between the bag body 1 and the frame body 5 into the groove 51. Part of air between the bag body 1 and the frame body 5 is extruded into the groove 51 for storage in the process of expanding the bag body 1, so that the outer surface of the bag body 1 can be contacted with the inner wall of the frame body 5, and the volume of the bag body 1 is ensured to be equal to a set target value.
The present embodiment also provides a replacement fluid preparation system using a fluid supply bag, as shown in fig. 1 and 4, comprising the fluid supply bag 6, and a blood circuit 7, a blood filter 8, a replacement fluid circuit 9, a dialysate supply switching circuit and a waste liquid discharge circuit 11, wherein the fluid supply bag 6 is communicated with an inlet of the replacement fluid circuit 9; the first inlet of the blood filter 8 is communicated with the outlet of the dialysate supply switching loop and the artery of the human body through the blood loop 7, and the first outlet of the blood filter 8 communicated with the inlet is communicated with the vein of the human body through the blood loop 7; the second inlet of the blood filter 8 is communicated with the outlet of the replacement liquid circuit 9 through a dialysate supply switching circuit, and the second outlet of the blood filter 8 communicated with the inlet is discharged outwards through the dialysate supply switching circuit and a waste liquid discharge circuit 11; the dialysate supply switching loop comprises at least two supply loops, wherein each supply loop is alternately communicated with or closed to the second inlet of the blood filter 8, and each supply loop is alternately communicated with or closed to the second outlet of the blood filter 8, so as to form a switching continuous supply structure.
The number of the liquid supply bags 6 is three, and three solutions are prepared by filling the liquid supply bags 6 with reverse osmosis water; the replacement liquid loop 9 comprises a first liquid pump 91, a second liquid pump 92, a third liquid pump 93, a mixer 94 and a clean filter 95, wherein inlets of the first liquid pump 91, the second liquid pump 92 and the third liquid pump 93 are respectively communicated with liquid pipes 2 on the three liquid supply bags 6; the outlets of the first, second and third liquid pumps 91, 92, 93 are communicated with the inlet of the mixer 94 to mix the three solutions; the outlet of the mixer 94 communicates with the inlet of the dialysate supply switching loop through a clean filter 95.
Before connecting the three fluid supply bags 6 with the inlet of the replacement fluid circuit 9, the bag body 1 is filled with reverse osmosis water to prepare three solutions with corresponding concentrations, and the three solutions are mixed in the replacement circuit to prepare dialysate and are supplied to the dialysate supply switching circuit. Because the solution of the liquid supply bag 6 is simple, convenient and accurate in proportioning, a large number of liquid supply bags 6 meeting the concentration requirement can be rapidly proportioned to replace the used liquid supply bags 6 at any time, the time for changing bags is greatly reduced, and the working efficiency is improved.
The dialysate supply switching loop comprises a first electronic scale 101 and a second electronic scale 102, wherein a replacement liquid storage bag 103 and a waste liquid storage bag 104 are weighed on the first electronic scale 101 and the second electronic scale 102, an inlet of the replacement liquid storage bag 103 is communicated with an outlet of the mixer 94 through an electromagnetic valve 105 and a clean filter 95, and an outlet of the replacement liquid storage bag 103 is communicated with a first inlet and a second inlet of the blood filter 8 through the electromagnetic valve to form a two-way input supply switching structure; the inlet of the waste liquid storage bag 104 is communicated with the second outlet of the blood filter 8 through the electromagnetic valve 105, and the outlet of the waste liquid storage bag 104 is communicated with the outside through the electromagnetic valve 105 to form a two-way output supply switching structure. After the solutions of the three fluid supply bags 6 are formulated into dialysate in the substitution fluid circuit 9, the dialysate is subjected to one of the supply circuits and stored in the substitution fluid storage bag 103. When the solution in the solution supplying bag 6 is used up, the matched new supplying bag can be quickly replaced for continuous supply, the condition that the supply of the solution is interrupted can be prevented, and the treatment effect is improved. When the dialysate in the replacement fluid storage bag 103 of the supply loop is used up, the control device controls the working state of the corresponding electromagnetic valve 105 to enable the replacement fluid loop 9 to be communicated with the other supply loop so that the dialysate flows into the replacement fluid storage bag 103 of the other supply loop, the whole process does not need to stop for changing the dialysate, continuous supply of the dialysate is ensured, the liquid flow and the pressure are stable, the working is stable and reliable, the blood pressure of a patient is stable during treatment, headache, nausea and vomiting are greatly reduced, and the treatment effect is greatly improved.
The blood circuit 7 comprises a first pressure monitor 71, a liquid pump 72, an anticoagulant injection device 73, a second pressure monitor 74, a second mixer 75, a liquid level monitor 76 and a bubble blocking clip 77, wherein an artery of a human body is communicated with a first inlet of the blood filter 8 through the first pressure monitor 71, the liquid pump 72, the anticoagulant injection device 73 and the mixer, and a first outlet of the blood filter 8 communicated with the inlet is communicated with a vein of the human body through the second pressure monitor 74, the liquid level monitor 76 and the bubble blocking clip 77.
The artery of the patient is communicated with the first inlet of the blood filter 8 through the arterial puncture needle, and the first pressure monitor 71, the liquid pump 72, the anticoagulant injection device 73 and the second mixer 75 are sequentially communicated with the first inlet of the blood filter 8; after the blood flows into the arterial puncture needle, the anticoagulant is injected by the anticoagulant injection device 73, and then is introduced into the second mixer 75 by the liquid pump 72. The blood is mixed with the dialysate in the second mixer 75 and then fed into the blood filter 8 through the first inlet of the blood filter 8. In which the toxin-containing dialysate is filtered, clean blood is output from the first outlet of the blood filter 8, flows into the vein of the human body through the second pressure monitor 74, the fluid level monitor 76 and the air-blocking clip 77 in this order, and is returned to the patient.
The waste liquid discharge circuit 11 includes a liquid pump 72 and a waste liquid bag 111, an inlet of the liquid pump 72 communicates with the second outlet of the blood filter 8, and an outlet of the liquid pump 72 communicates with the waste liquid bag. The flow rate of the waste liquid discharged to the waste liquid bag 111 can be adjusted by the liquid pump 72 to be in the range of 0-2000 ml/h, the flow rate of the ultra-filtered waste liquid can be adjusted at any time, clinical use is convenient, the ultra-filtered waste liquid is filled into the waste liquid bag 111 with scales, the amount of the ultra-filtered liquid can be known in real time, and the amount of the ultra-filtered liquid is the dehydration amount of a patient.
Example 2
In this embodiment, as an improvement of the frame 5 in the embodiment 1, as shown in fig. 1 and 3, in order to prevent a portion of air between the bag 1 and the frame 5 from flowing out from the upper end of the frame 5 during the expansion of the bag 1, the air is sealed between the bag 1 and the frame 5, and the bag 1 cannot expand to a volume equal to the internal volume of the frame 5, resulting in a higher concentration of the solution prepared in the bag 1. The wall of the frame body 5 is provided with a through hole 52, and when reverse osmosis water enters the bag body 1 through the liquid pipe 2, the outer surface of the bag body 1 is contacted with the inner surface of the frame body 5, so that air between the bag body 1 and the frame body 5 is extruded to the outside of the frame body 5 through the through hole 52. Part of the air between the bag body 1 and the frame body 5 is extruded and discharged into the frame body 5 through the through holes 52 in the process of expanding the bag body 1, so that the outer surface of the bag body 1 can be contacted with the inner wall of the frame body 5, and the volume of the bag body 1 is ensured to be equal to a set target value. Thereby ensuring that the concentration of the proportioning solution of the bag body 1 meets the required requirement.
The above disclosure is only a preferred embodiment of the present invention, and it is needless to say that the scope of the invention is not limited thereto, and therefore, the equivalent changes according to the claims of the present invention still fall within the scope of the present invention.
Claims (8)
1. A replacement fluid dispensing system employing a fluid supply bag, characterized by: the blood supply device comprises a liquid supply bag, a blood circuit, a blood filter, a replacement liquid circuit, a dialysis liquid supply switching circuit and a waste liquid discharge circuit, wherein the liquid supply bag comprises a bag body made of flexible materials, and a liquid port for flowing liquid into and out of the bag body and a gas port for flowing air into and out of the bag body are formed in the bag body; the liquid port is internally provided with a liquid pipe which is connected with the bag body in a sealing way; the tail end of the liquid pipe extends into the inner bottom of the bag body, and the bag body is internally provided with a corresponding amount of concentrated liquid or dry powder according to the volume of the bag body and the concentration of the solution required; vacuumizing the bag body, and injecting reverse osmosis water into the bag body through the liquid pipe when a solution is required to be prepared;
the outer part of the bag body is sleeved with a frame body for generating stretching deformation of the bag body;
the liquid supply bag is communicated with the inlet of the replacement liquid loop; the first inlet of the blood filter is communicated with the outlet of the dialysate supply switching loop and the artery of the human body through the blood loop, and the first outlet of the blood filter communicated with the inlet is communicated with the vein of the human body through the blood loop; the second inlet of the blood filter is communicated with the outlet of the replacement liquid loop through the dialysate supply switching loop, and the second outlet of the blood filter communicated with the inlet is discharged outwards through the dialysate supply switching loop and the waste liquid discharge loop; the dialysate supply switching loop comprises at least two supply loops, wherein each supply loop is alternately communicated with or closed to a second inlet of the blood filter, and each supply loop is alternately communicated with or closed to a second outlet of the blood filter to form a switching continuous supply structure;
the number of the liquid supply bags is three, and the liquid supply bags are filled with reverse osmosis water to prepare three solutions; the replacement liquid loop comprises a first liquid pump, a second liquid pump, a third liquid pump, a mixer and a clean filter, wherein inlets of the first liquid pump, the second liquid pump and the third liquid pump are respectively communicated with liquid pipes on the three liquid supply bags; the outlets of the first liquid pump, the second liquid pump and the third liquid pump are communicated with the inlet of the mixer to mix the three solutions; the outlet of the mixer communicates with the inlet of the dialysate supply switching loop through a clean filter.
2. A replacement fluid dispensing system using a fluid supply bag as defined in claim 1, wherein: the dialysate supply switching loop comprises a first electronic scale and a second electronic scale, wherein a replacement liquid storage bag and a waste liquid storage bag are weighed on the first electronic scale and the second electronic scale, an inlet of the replacement liquid storage bag is communicated with an outlet of the mixer through an electromagnetic valve, and an outlet of the replacement liquid storage bag is communicated with a first inlet and a second inlet of the blood filter through the electromagnetic valve to form a two-way input supply switching structure; the inlet of the waste liquid storage bag is communicated with the second outlet of the blood filter through an electromagnetic valve, and the outlet of the waste liquid storage bag is communicated with the outside through the electromagnetic valve to form a two-way output supply switching structure.
3. A replacement fluid dispensing system using a fluid supply bag as defined in claim 1, wherein: the blood circuit comprises a first pressure monitor, a liquid pump, an anticoagulant injection device, a second pressure monitor, a second mixer, a liquid level monitor and a bubble blocking clamp, wherein an artery of a human body is communicated with a first inlet of a blood filter through the first pressure monitor, the liquid pump, the anticoagulant injection device and the mixer, and a first outlet of the blood filter communicated with the inlet is communicated with a vein of the human body through the second pressure monitor, the liquid level monitor and the bubble blocking clamp.
4. A replacement fluid dispensing system using a fluid supply bag as defined in claim 1, wherein: the waste liquid discharge loop comprises a liquid pump and a waste liquid bag, an inlet of the liquid pump is communicated with the second outlet of the blood filter, and an outlet of the liquid pump is communicated with the waste liquid bag.
5. A replacement fluid dispensing system using a fluid supply bag as defined in claim 1, wherein: the air port is provided with an air pipe, and the air pipe is connected with the air port in a sealing way.
6. A replacement fluid dispensing system using a fluid supply bag as defined in claim 1, wherein: the liquid pipe and the air pipe are connected into a whole through the connecting block.
7. A replacement fluid dispensing system using a fluid supply bag as defined in claim 1, wherein: the inner wall of the frame body is provided with a groove, and when reverse osmosis water enters the bag body through the liquid pipe, the outer surface of the bag body is contacted with the inner surface of the frame body so as to squeeze air between the bag body and the frame body into the groove.
8. A replacement fluid dispensing system using a fluid supply bag as defined in claim 1, wherein: the wall of the frame body is provided with a through hole, and when reverse osmosis water enters the bag body through the liquid pipe, the outer surface of the bag body is contacted with the inner surface of the frame body, so that air between the bag body and the frame body is extruded to the outside of the frame body through the through hole.
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| CN201611217987.8A CN106730085B (en) | 2016-12-26 | 2016-12-26 | Liquid supply bag and replacement liquid preparation system comprising same |
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| CN201611217987.8A CN106730085B (en) | 2016-12-26 | 2016-12-26 | Liquid supply bag and replacement liquid preparation system comprising same |
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| CN106730085B true CN106730085B (en) | 2024-04-05 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2019089579A1 (en) * | 2017-11-01 | 2019-05-09 | Baxter International Inc. | Mixing for online medical fluid generation |
| CN108498889A (en) * | 2018-05-09 | 2018-09-07 | 重庆天外天医疗器械有限公司 | The online compounding and controlling system of dialysis machine working solution and dialysis machine |
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