CN206526334U - peritoneal dialysis machine with on-line monitoring function - Google Patents

peritoneal dialysis machine with on-line monitoring function Download PDF

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Publication number
CN206526334U
CN206526334U CN201621328765.9U CN201621328765U CN206526334U CN 206526334 U CN206526334 U CN 206526334U CN 201621328765 U CN201621328765 U CN 201621328765U CN 206526334 U CN206526334 U CN 206526334U
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China
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dialysis
bag
glucose
monitoring function
abdominal cavity
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CN201621328765.9U
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周建辉
曹雪莹
谢大洋
黄静
蔡广研
陈香美
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Chinese PLA General Hospital
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Chinese PLA General Hospital
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Abstract

The utility model provides a kind of peritoneal dialysis machine for having and monitoring function on-line, and it includes:Dialysis main frame, which is provided with dialysis buffer bag, and the arrival end of the dialysis buffer bag is connected with the bag filters of multiple splendid attire glucose dialysis;Dialysis pipeline, its one end is connected with the port of export of dialysis buffer bag, its other end can be connected with abdominal cavity, and the dialysis pipeline is electrically connected provided with that can extract the glucose detector of the intraperitoneal abdominal cavity liquid, the glucose detector with the dialysis main frame;Waste pipe, its one end is connected with dialysis pipeline, and its other end is connected with waste fluid bag.The utility model can monitor intraperitoneal concentration of glucose in real time, to understand the ultrafiltration ability and transport function of peritonaeum, realize and adjust prescription in real time during peritoneal dialysis.

Description

Peritoneal dialysis machine with on-line monitoring function
Technical field
The utility model is related to medical instruments field, specifically a kind of peritoneal dialysis machine, particularly a kind of to have online prison The peritoneal dialysis machine of brake.
Background technology
Peritoneal dialysis (peritoneal dialysis, PD) be by the use of human body itself peritonaeum as dialysis membrane one kind Dialysis, it is by pouring into the dialyzate in abdominal cavity and the composition progress solute and moisture in the capillary of peritonaeum opposite side Exchange, remove the metabolite and excessive moisture content that are detained in vivo, while material necessary to supplementing body by dialyzate, To realize the purpose for the treatment of.
At present, will by the dialysis catheter being connected with automated peritoneal dialysis machine (APD machines) when carrying out peritoneal dialysis treatment Dialyzate is filled into abdominal cavity, and ectoperitoneal waste and unnecessary moisture content enter intraperitoneal through peritonaeum, and are contained by dialysis catheter handle The peritoneal dialysis solution for having waste and excessive moisture is discharged in waste fluid bag from intraperitoneal, then fills into new dialyzate, constantly Circulation, still, existing automated peritoneal dialysis machine be be irrigated according to the prescription set before, indwelling and drainage, its There is no on-line real time monitoring function, it is impossible to understand the ultrafiltration ability and transport function of peritonaeum in time, so that it cannot basis in time The situation of patient changes prescription.
The problem of existing in view of above-mentioned prior art, the present inventor combines the design for many years of related manufacture field and used Experience is there is provided a kind of peritoneal dialysis machine for having and monitoring function on-line, to overcome drawbacks described above.
Utility model content
The purpose of this utility model is to provide a kind of peritoneal dialysis machine with on-line monitoring function, and it can monitor abdomen in real time The concentration of glucose of intracavitary, to understand the ultrafiltration ability and transport function of peritonaeum, realization is adjusted in real time during peritoneal dialysis Prescription.
Above-mentioned purpose of the present utility model can be realized using following technical proposal:
The utility model provides a kind of peritoneal dialysis machine for having and monitoring function on-line, and it includes:Dialysis main frame, sets thereon There is dialysis buffer bag, the arrival end of the dialysis buffer bag is connected with the bag filter of multiple splendid attire glucose dialysis;Dialysis tubing Road, its one end is connected with the port of export of dialysis buffer bag, and its other end can be connected with abdominal cavity, is set on the dialysis pipeline There is the glucose detector that can extract the intraperitoneal abdominal cavity liquid, the glucose detector is electrically connected with the dialysis main frame Connect;Waste pipe, its one end is connected with dialysis pipeline, and its other end is connected with waste fluid bag.
In a preferred embodiment, the dialysis tubing great distance is provided with dialysis catheter, institute from one end of the dialysis main frame Dialysis pipeline is stated by the dialysis catheter with the abdominal cavity to be connected.
In a preferred embodiment, cassette, the card are provided between the dialysis buffer bag and multiple bag filters Multiple paths are provided with casket, each bag filter is connected by path described in one with dialysis buffer bag.
In a preferred embodiment, the path of the cassette is provided with valve.
In a preferred embodiment, the valve is electrically connected with the dialysis main frame.
In a preferred embodiment, the dialysis main frame is provided with heater, and the heater is located at the dialysis buffer The lower section of bag.
In a preferred embodiment, multiple bag filters include at least one concentration regulation bag and multiple dialyzates Bag.
In a preferred embodiment, the concentration of the glucose dialysis in the concentration regulation bag is higher than the dialyzate The concentration of glucose dialysis in bag.
In a preferred embodiment, the bag filter is four, and four bag filters include the concentration and adjusted Save bag and three dialyzate bags.
In a preferred embodiment, the glucose detector is provided with alarm and can extract the intraperitoneal abdominal cavity The suction pump of liquid.
The characteristics of the utility model has the peritoneal dialysis machine of on-line monitoring function and advantage are:
The utility model can extract abdominal cavity by setting glucose detector on dialysis pipeline by glucose detector Interior abdominal cavity liquid, carries out real-time online detection, and result is fed back into dialysis main frame in real time, intraperitoneal to monitor in real time The concentration of glucose of abdominal cavity liquid, understands the ultrafiltration ability and transport function of peritonaeum, determines intraperitoneal abdominal cavity liquid in real time It is optimal to stay the abdomen time, and the adjustment of progress prescription (adjusts the concentration and intraperitoneal abdomen of the glucose dialysis of perfusion in time Chamber liquid stays the abdomen time), moreover, the utility model can also as peritoneal dialysis clinical research instrument, by collecting many cases The data of different transhipment state patients, set up the estimation transshipment model of peritonaeum under different transhipment states, beneficial to scientific research.
Brief description of the drawings
, below will be to needed for embodiment description in order to illustrate more clearly of the technical scheme in the utility model embodiment The accompanying drawing to be used is briefly described, it should be apparent that, drawings in the following description are only some realities of the present utility model Example is applied, for those of ordinary skill in the art, on the premise of not paying creative work, can also be according to these accompanying drawings Obtain other accompanying drawings.
Fig. 1 is the use schematic diagram for the peritoneal dialysis machine that the utility model has on-line monitoring function;
Fig. 2 is the intraperitoneal glucose concentration curve figure real-time monitored during indwelling by the utility model.
Drawing reference numeral explanation:
1 dialysis main frame, 2 dialysis buffers bag, 3 concentration regulation bag, 4 dialyzate bags, 5 cassettes, 6 dialysis pipelines, 7 dialysis are led Pipe, 8 glucose detectors, 9 waste pipes, 10 waste fluid bags, 11 abdominal cavities, 12 peritonaeums, D0 initial glucose concentrations, the real-time grapes of Dt Sugared concentration, the real-time ultrafiltration potential energy of Et, level1 human normal blood glucose values, level2 blood glucose warning values, α angles.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the utility model embodiment is carried out Clearly and completely describe, it is clear that described embodiment is only a part of embodiment of the utility model, rather than whole Embodiment.Based on the embodiment in the utility model, those of ordinary skill in the art are not under the premise of creative work is made The every other embodiment obtained, belongs to the scope of the utility model protection.
It is divided into three kinds of states in peritoneal dialysis treatment:Perfusion is (i.e. to Peritoneal Infusions dialyzate), indwelling is (even if dialyzate Stopped intraperitoneal) and drainage (draining by intraperitoneal abdominal cavity liquid), three kinds of states are in dialysis procedure It is alternately.
As shown in figure 1, the utility model provides a kind of peritoneal dialysis machine for having and monitoring function on-line, it includes:Dialysis Main frame 1, which is provided with dialysis buffer bag 2, the arrival end of the dialysis buffer bag 2 and the dialysis of multiple splendid attire glucose dialysis Bag is connected;Dialysis pipeline 6, its one end is connected with the port of export of dialysis buffer bag 2, and its other end can be connected with abdominal cavity 11 Logical, the dialysis pipeline 6 is provided with the glucose detector 8 for the abdominal cavity liquid that can be extracted in the abdominal cavity 11, the glucose Detector 8 is electrically connected with the dialysis main frame 1;Waste pipe 9, its one end is connected with dialysis pipeline 6, its other end and waste fluid bag 10 are connected.
Further, as shown in figure 1, the one end of the dialysis pipeline 6 away from the dialysis main frame 1 is provided with dialysis catheter 7, The dialysis pipeline 6 is connected by the dialysis catheter 7 with the abdominal cavity 11, i.e., dialysis catheter 7 can penetrate the abdominal cavity of patient In 11, make dialysis main frame 1 that the glucose dialysis in pipeline 6 of dialysing be injected into abdominal cavity of patients 11 by dialysis catheter 7, or, Make dialysis main frame 1 that the abdominal cavity liquid that abdominal cavity of patients 11 includes waste liquid be extracted out and is discharged into through waste pipe 9 useless by dialysis catheter 7 Liquid bag 10, preferably, glucose detector 8 is located at the junction of the dialysis catheter 7 and the dialysis pipeline 6.
Further, it is described as shown in figure 1, being provided with cassette 5 between dialysis buffer bag 2 and multiple bag filters Multiple paths are provided with cassette 5, each bag filter is connected by path described in one with dialysis buffer bag 2, the card The path of casket 5 is provided with valve, and the valve is electrically connected with the dialysis main frame 1, to realize opening for valve by main frame 1 of dialysing Close;When not working, the valve closed by main frame 1 of dialysing on all paths prevents the glucose dialysis stream in bag filter Enter in dialysis buffer bag 2, when starting working, unlatching some path selected according to required concentration of glucose by dialysis main frame 1 On valve, with by the bag filter being connected with the path to dialysis buffer bag 2 in supply glucose dialysis, at work, If there is sufficient glucose dialysis in dialysis buffer bag 2, all valves can be also closed, are stopped to dialysis buffer bag Supply glucose dialysis in 2, if necessary to adjustment prescription, (namely the glucose that adjustment is supplied in dialysis buffer bag 2 is dense Degree), then the valve that correspondence contains the bag filter of different concentration of glucose can be opened by main frame 1 of dialysing.
Further, the dialysis main frame 1 is provided with heater, and the heater is located at the lower section of dialysis buffer bag 2, To be heated by heater to the glucose dialysis in dialysis buffer bag 2, make the glucose entered in abdominal cavity of patients 11 The temperature of dialyzate meets the normal temperature of human body, it is to avoid the glucose dialysis of low temperature enters abdominal cavity of patients 11, and body is brought to patient Discomfort on body.
Further, as shown in figure 1, multiple bag filters, which include at least one concentration, adjusts bag 3 and multiple dialyzates The concentration of glucose dialysis in bag 4, the concentration regulation bag 3 is higher than the glucose dialysis in the dialyzate bag 4 The concentration of the glucose dialysis contained in concentration, multiple dialyzate bags 4 is equal, in filling process, can be used only Dialyzate bag 4 supplies glucose dialysis into dialysis buffer bag 2, certainly, in the case where needing to adjust the situation of prescription, can also lead to Cross dialysis main frame 1 and open the valve buffered between bag filter 2 and concentration regulation bag 3 at any time, concentration is adjusted bag 3 to dialysis buffer The glucose dialysis of supply high concentrations in bag 2, and then adjust the concentration of the glucose dialysis of perfusion into abdominal cavity 11.
It is preferred that, the bag filter is four, and four bag filters include a concentration regulation bag 3 and three institutes Dialyzate bag 4 is stated, to meet the demand of Most patients dialysis, it is of course also possible to the need for according to actual dialysis, select it He adjusts bag 3 and dialyzate bag 4 at appropriate number of concentration, and this is not restricted.
Further, the glucose detector 8 is provided with alarm and the abdominal cavity liquid that can be extracted in the abdominal cavity 11 Suction pump, specifically, alarm can be alarm sound, the abdominal cavity liquid in the abdominal cavity 11 that glucose detector 8 is detected Concentration of glucose be equal to or less than or micro- be more than (such as higher than the 5% of blood glucose warning value) (its during blood glucose warning value level2 Middle blood glucose warning value level2=human normals blood glucose value level1 × 150%, blood glucose warning value level2 be consider colloid and Hydrostatic pressing factor etc. and artificially define), alarm sound can send alarm, remind medical worker to handle in time, stopping stay abdomen or Adjust prescription, the suction pump of glucose detector 8 can at any time or the abdominal cavity liquid in the extraction abdominal cavity 11 of constant duration is to enter The detection of row concentration of glucose, it can automatically control glucose detector 8 by main frame 1 of dialysing and be extracted and detected work Make, manually can also directly operate glucose detector 8 to be extracted and detected work, glucose detector 8 is provided with display circle Face, it can directly display the curve map of the concentration of glucose in the abdominal cavity 11 real-time monitored, certainly, glucose detector 8 The result of detection can also be fed directly to main frame 1 of dialysing, shown by the display interface for main frame 1 of dialysing in abdominal cavity 11 The curve map of concentration of glucose, wherein, the other structures of glucose detector 8 are existing known structure, are no longer gone to live in the household of one's in-laws on getting married herein State, meanwhile, dialysis main frame 1 can will not be repeated here for existing automated peritoneal dialysis machine in the prior art, its structure.
The utility model has the peritoneal dialysis machine of on-line monitoring function operationally, is irrigated first, passes through dialysis Liquid bag 4 supplies glucose dialysis into buffering bag filter 2, buffers the glucose dialysis in bag filter 2 in dialysis main frame 1 In the presence of heater, the temperature (about 36.5 DEG C or so) with human body normal temperature is heated to, is then led by pipeline 6 of dialysing through dialysis Pipe 7 is filled into abdominal cavity 11 (i.e. using glucose as bleeding agent in intraperitoneal carry out ultrafiltration), as defined in filling point side to be achieved After amount, stop perfusion, start indwelling, after after indwelling for a period of time, carry out drainage, i.e., pass through the abdominal cavity liquid in abdominal cavity 11 saturating Analysis conduit 7, which is drained, to be come, and is entered through waste pipe 9 in waste fluid bag 10, the above-mentioned work of repetition so moved in circles, to remove The metabolite and excessive moisture content being detained in vivo realize treatment;
Specifically, during indwelling, by glucose detector 8 in real time or constant duration or extraction at any time Abdominal cavity liquid sample in abdominal cavity 11, the concentration of glucose of the abdominal cavity liquid in abdominal cavity 11 is detected by glucose detector 8, is obtained Go out glucose concentration curve, as shown in Figure 2 (it is to detect the glucose concentration curve once drawn in every 10 minutes), it can pass through Glucose detector 8 or dialysis main frame 1 are shown;Period, because the concentration of glucose in abdominal cavity 11 is higher than outside abdominal cavity 11, so Entering into the trans-abdominal formation excess of export of film 12 liquid of branch in abdominal cavity 11 in the capillary in the outside of abdominal cavity 11, while in abdominal cavity 11 Glucose can also be penetrated into capillary by peritonaeum 12 and is absorbed by the body, and make the glucose of abdominal cavity liquid in abdominal cavity 11 dense Degree is gradually reduced, and the ultrafiltration ability of peritonaeum 12 is also declined, i.e. the glucose by monitoring the abdominal cavity liquid in abdominal cavity 11 in real time Concentration realizes the real-time assessment to the ultrafiltration ability of peritonaeum 12;When real-time concentration of glucose Dt drops to blood glucose warning value level2 When, the alarm of glucose detector 8 can send alarm, remind medical worker or patient to stop staying abdomen, i.e., be now abdominal cavity The optimal of abdominal cavity liquid in 11 stays the abdomen time (namely if necessary to increase excess of export liquid, then to stay the abdomen time to be longer than most preferably Stay the abdomen time);When real-time concentration of glucose Dt drops between human normal blood glucose value level1 and blood glucose warning value level2 When, the alarm of glucose detector 8 can send second of alarm, and it is that will appear from negative ultrafiltration to remind medical worker or patient;When When real-time concentration of glucose Dt is equal to human normal blood glucose value level1, signal can be fed directly to by glucose detector 8 Main frame 1 is analysed, dialysis main frame 1 is controlled to stop staying abdomen to carry out drainage immediately, or the valve on passage is opened in the dialysis control of main frame 1, Make the concentration of receiving high concentration glucose dialyzate adjust bag 3 to be irrigated to abdominal cavity 11 immediately through dialysis buffer bag 2;
Meanwhile, as shown in Fig. 2 the line and level between initial glucose concentration D0 and real-time concentration of glucose Dt are linear Have angle α, and the slope k (i.e. k=tan α) of the angle α represents the decline speed of concentration of glucose, and slope is bigger, illustrates peritonaeum 12 ultrafiltration ability decline is faster, and, real-time concentration of glucose Dt and human normal blood glucose value level1 difference is super in real time Potential energy Et is filtered, its value is represented as negative ultrafiltration, that is, passes through real-time ultrafiltration potential energy Et, slope k just, to be represented as ultrafiltration, its value is negative The time that negative ultrafiltration occurs can be estimated out with real-time concentration of glucose Dt, abdomen is stayed with timely stopping, drainage is carried out immediately, or Prescription is adjusted immediately, i.e., dialysis main frame 1 is fed back to by the result for detecting glucose detector 8, main frame 1 is adjusted by dialysing Each valve, makes the concentration of the glucose dialysis with high concentration adjust bag 3 and is connected with dialysis buffer bag 2, with into abdominal cavity 11 Perfusion, to adjust the concentration of glucose of the abdominal cavity liquid in abdominal cavity 11, it is to avoid the appearance of negative ultrafiltration;
In addition, the real-time concentration of glucose Dt detected by any position in fig. 2 can also reflect the transhipment work(of peritonaeum Can, specifically, calculate real-time concentration of glucose Dt and the initial glucose concentration D0 of detection ratio, and by the ratio and abdominal cavity Standard value (the Transport status that such as table 1 below is recorded of blance test (peritoneal equilibration test, PET) Assess table) contrasted, to determine patient's peritonaeum Solute Transport type, and prescription is timely adjusted according to the result;
The Transport status of table 1. assesses table
In perfusion or drainage process, can also as needed constant duration or pause perfusion or drainage at any time, To extract the abdominal cavity liquid sample in abdominal cavity 11 by glucose detector 8, the Portugal of the abdominal cavity liquid in abdominal cavity 11 is detected in time Grape sugar concentration, to monitor the concentration of glucose in abdominal cavity 11 in real time, grasps the ultrafiltration ability and transport function of peritonaeum 12 in time, and Result that glucose detector 8 is detected is presented to doctor and patient by display screen in real time, and feeds back to dialysis main frame 1, With the unlatching for each valve that cassette is controlled by main frame 1 of dialysing, or (namely the drainage of abdomen time stayed by the control of main frame 1 of dialysing Time started), realize the adjustment of prescription.
The characteristics of the utility model has the peritoneal dialysis machine of on-line monitoring function and advantage are:
The utility model can be extracted by setting glucose detector 8 on dialysis pipeline 6 by glucose detector 8 Abdominal cavity liquid in abdominal cavity 11, carries out real-time online detection, and result is fed back into dialysis main frame 1 in real time, to monitor in real time The concentration of glucose of abdominal cavity liquid in abdominal cavity 11, understands the ultrafiltration ability and transport function of peritonaeum 12, determines abdominal cavity 11 in real time The optimal of interior abdominal cavity liquid stays the abdomen time, and carry out in time prescription adjustment (adjust perfusion glucose dialysis it is dense Abdominal cavity liquid in degree and abdominal cavity 11 stays the abdomen time), moreover, the utility model can also as peritoneal dialysis clinical research work Tool, by collecting the data of the different transhipment state patients of many cases, sets up the estimation transshipment model of peritonaeum under different transhipment states, profit In scientific research.
The schematical embodiment of the utility model is the foregoing is only, and is not used to limit model of the present utility model Enclose.Any those skilled in the art, the equivalent variations made on the premise of principle of the present utility model and design is not departed from With modification, protection domain of the present utility model all should be belonged to.

Claims (10)

1. a kind of have the peritoneal dialysis machine for monitoring function on-line, it is characterised in that described to have the peritonaeum for monitoring function on-line Dialysis machine includes:
Dialysis main frame, which is provided with dialysis buffer bag, the arrival end and multiple splendid attire glucose dialysis of the dialysis buffer bag Bag filter be connected;
Dialysis pipeline, its one end is connected with the port of export of dialysis buffer bag, and its other end can be connected with abdominal cavity, described Analysis pipeline is provided with extracting the glucose detector of the intraperitoneal abdominal cavity liquid, the glucose detector and described Analyse main frame electrical connection;
Waste pipe, its one end is connected with dialysis pipeline, and its other end is connected with waste fluid bag.
2. according to claim 1 have the peritoneal dialysis machine for monitoring function on-line, it is characterised in that the dialysis pipeline One end away from the dialysis main frame is provided with dialysis catheter, and the dialysis pipeline is connected by the dialysis catheter with the abdominal cavity It is logical.
3. according to claim 1 have the peritoneal dialysis machine for monitoring function on-line, it is characterised in that the dialysis buffer It is provided between bag and multiple bag filters in cassette, the cassette and is provided with multiple paths, each bag filter passes through an institute Path is stated with dialysis buffer bag to be connected.
4. the peritoneal dialysis machine with on-line monitoring function according to claim 3, it is characterised in that the cassette it is logical Road is provided with valve.
5. according to claim 4 have the peritoneal dialysis machine for monitoring function on-line, it is characterised in that the valve and institute State dialysis main frame electrical connection.
6. according to claim 1 have the peritoneal dialysis machine for monitoring function on-line, it is characterised in that the dialysis main frame Provided with heater, the heater is located at the lower section of dialysis buffer bag.
7. according to claim 1 have the peritoneal dialysis machine for monitoring function on-line, it is characterised in that multiple dialysis Bag includes at least one concentration and adjusts bag and multiple dialyzate bags.
8. according to claim 7 have the peritoneal dialysis machine for monitoring function on-line, it is characterised in that the concentration regulation Concentration of the concentration of glucose dialysis in bag higher than the glucose dialysis in the dialyzate bag.
9. the peritoneal dialysis machine with on-line monitoring function according to claim 7, it is characterised in that the bag filter is Four, four bag filters include a concentration regulation bag and three dialyzate bags.
10. according to claim 1 have the peritoneal dialysis machine for monitoring function on-line, it is characterised in that the glucose Detector is provided with alarm and can extract the suction pump of the intraperitoneal abdominal cavity liquid.
CN201621328765.9U 2016-12-06 2016-12-06 peritoneal dialysis machine with on-line monitoring function Active CN206526334U (en)

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Application Number Priority Date Filing Date Title
CN201621328765.9U CN206526334U (en) 2016-12-06 2016-12-06 peritoneal dialysis machine with on-line monitoring function

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Application Number Priority Date Filing Date Title
CN201621328765.9U CN206526334U (en) 2016-12-06 2016-12-06 peritoneal dialysis machine with on-line monitoring function

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CN206526334U true CN206526334U (en) 2017-09-29

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110090328A (en) * 2019-06-19 2019-08-06 张磊 A kind of peritoneal dialysis catheters
US11255844B2 (en) 2018-03-06 2022-02-22 Fresenius Medical Care Holdings, Inc. Peritoneal dialysis systems and related methods

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11255844B2 (en) 2018-03-06 2022-02-22 Fresenius Medical Care Holdings, Inc. Peritoneal dialysis systems and related methods
CN110090328A (en) * 2019-06-19 2019-08-06 张磊 A kind of peritoneal dialysis catheters
CN110090328B (en) * 2019-06-19 2021-11-26 张磊 Peritoneal dialysis catheter

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