CN206450598U - Collaurum quantitative fluorescence analysis all-in-one - Google Patents
Collaurum quantitative fluorescence analysis all-in-one Download PDFInfo
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- CN206450598U CN206450598U CN201720080690.5U CN201720080690U CN206450598U CN 206450598 U CN206450598 U CN 206450598U CN 201720080690 U CN201720080690 U CN 201720080690U CN 206450598 U CN206450598 U CN 206450598U
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Abstract
The utility model discloses collaurum quantitative fluorescence analysis all-in-one, including body and display screen；Provided with microprocessor and the lighting unit, shooting unit, graphics processing unit, laser and the first photoelectric sensor that are connected with microprocessor in body；Shooting unit is used to carry out optical pickup to test card and draws shooting result；Graphics processing unit is used to analyze and process shooting result, draws test card nature controlling line gray value and detection line gray value；Laser is used to make test card send fluorescence test card progress laser irradiation；First photoelectric sensor is used to receive fluorescence and be processed as electric signal to send to microprocessor；Microprocessor draws testing result by calculating the electric signal of nature controlling line gray value and the first photoelectric sensor of ratio or processing of detection line gray value.All-in-one of the present utility model can both work as colloidal gold chart reader and use, and immunofluorescence analysis instrument can be worked as again and is used, cost is saved.
Description
Technical field
The utility model is related to clinical detection technique field, in particular to a kind of collaurum quantitative fluorescence analysis all-in-one.
Background technology
Existing clinical testing laboratories would generally be entered using collaurum method or immunofluorescence method to a variety of physicochemical datas
Row detection, common instrument has colloidal gold chart reader, immunofluorescence analysis instrument etc..But two kinds of instruments are combined into due to lacking one kind
The instrument of one, causes laboratory to be generally equipped with above two instrument, and the different test cards that above two instrument is directed to are needed
Laboratory technician's mark differentiation is wanted, is unfavorable for conventional efficient raising.
Utility model content
The purpose of this utility model seeks to overcome existing clinical detection instrument single, it is impossible to while using collaurum side
There is provided a kind of collaurum quantitative fluorescence analysis one for the problem of method or immunofluorescence method are detected to a variety of physicochemical datas
Machine, it has the characteristics of being detected again using immunofluorescence method to a variety of physicochemical datas using collaurum method.
To achieve the above object, the collaurum quantitative fluorescence analysis all-in-one designed by the utility model, including body and
Turnover sample opening and display screen on the body；Microprocessor is provided with the body and is connected with the microprocessor
Lighting unit, shooting unit, graphics processing unit, laser and the first photoelectric sensor；
The turnover sample opening is used to being put into or taking out test card；
The lighting unit is used to export illumination light to the test card；
The shooting unit is used to carry out optical pickup to the test card and draws shooting result；
Described image processing unit is used to analyze and process the shooting result of the shooting unit, draws test card matter
Control line gray value and detection line gray value；
The laser is used to carry out laser irradiation to the test card, the test card is sent fluorescence；
First photoelectric sensor is used to receive the fluorescence and be processed as electric signal according to fluorescence intensity to send to institute
State microprocessor；
The microprocessor is by calculating the ratio of nature controlling line gray value and detection line gray value or handling first light
The electric signal of electric transducer draws testing result；
The display screen is used to show the testing result.
Further, it is additionally provided with the body and is connected with the microprocessor and institute is stretched out by the turnover sample opening
State the sampling device of body；The sampling device includes the test paper disk for being used to hold the level of multiple test cards and for solid
The sample injection disc of the level of the fixed test paper disk；The test paper disk upper surface is provided with multiple cards with the test card corresponding matching
Groove；The sample introduction tray bottom is provided with slide rail, and sample injection disc side wall is provided with the rack set along sidewall direction；It is additionally provided with the body
The gear and the motor of the driving pinion rotation coordinated with the rack；The motor is connected with the microprocessor；It is described
Lighting unit, shooting unit, laser and the first photoelectric sensor are directly over the test paper disk.
The beneficial effect of above-mentioned further scheme is：By the way that multiple test cards are placed in the neck of test paper disk so that one
Individual test paper disk can improve detection efficiency with the multiple test cards of stationary arrangement；And pass through sample injection disc and rack, the tooth of sample injection disc side wall
The effect of wheel and motor, with Automated condtrol sample introduction and can go out sample, and sample introduction is stable, is not in test paper caused by manual operation
The problems such as card inclination is rocked.
Preferably, the second photoelectric sensor located at the sampling device both sides, the test paper are additionally provided with the body
Disk is provided with the raised catch for being used for cutting off second photo-sensor signal, second photoelectricity in each neck side
Sensor is connected with the microprocessor.
The beneficial effect of above-mentioned preferred scheme is：Pass through the positioning action of the second photoelectric sensor and catch so that micro- place
Managing device effectively controlled motor can work, so as to limit each displacement of sample injection disc in Test paper card as two test paper
The distance between card, so as to often detect a test card, sample injection disc reach once causes next test card is in be detected
Region.
Further, in addition to it can be sticked being used for the test card area on the test paper disk or on the test card
It is divided into the identification code of colloidal gold test paper card or immunofluorescence test card.
The beneficial effect of above-mentioned further scheme is：By the effect of identification code, it may be such that all-in-one is automatic by test card
Colloidal gold test paper card or immunofluorescence test card are divided into, so that detected accordingly for the test card, it is less unnecessary
Experimental procedure, improve detection efficiency.
Preferably, the test paper disk and the removable connection of the sample injection disc.
The beneficial effect of above-mentioned preferred scheme is：By by test paper disk and the removable connection of sample injection disc so that test paper disk is torn open
After unloading, test card more convenient and quicker is placed.
Further, the test paper disk is provided with positioning through hole；The sample injection disc is provided with to be coordinated with the positioning through hole
Alignment pin.
The beneficial effect of above-mentioned further scheme is：By the effect of alignment pin and positioning through hole, prevent sample injection disc in shifting
Test paper disk is subjected to displacement with it during dynamic.
Preferably, the test card is colloidal gold test paper card or immunofluorescence test card.
Further, the upper surface of the test paper disk each neck side be provided be used for identify the neck numbering or
Label.
The beneficial effects of the utility model are：Pass through microprocessor and connected lighting unit, shooting unit, image
The effect of processing unit, laser and the first photoelectric sensor so that all-in-one of the present utility model can both work as collaurum reading
Card instrument is used, and immunofluorescence analysis instrument can be worked as again and is used, cost is saved, and only needs single injected sampling to can detect multiple scribble
The test card of sample, is colloidal gold test paper card or immunofluorescence test card without test card is distinguished, reduces experimental procedure, carry
High conventional efficient.
Brief description of the drawings
Fig. 1 is the dimensional structure diagram of the utility model collaurum quantitative fluorescence analysis all-in-one.
Fig. 2 is the principle schematic of the utility model collaurum quantitative fluorescence analysis all-in-one.
Fig. 3 shows for the structure that the test paper disk of the utility model collaurum quantitative fluorescence analysis all-in-one is installed on sample injection disc
It is intended to.
Fig. 4 is the dimensional structure diagram of sample injection disc in Fig. 3.
Fig. 5 is the schematic top plan view of test paper disk in Fig. 3.
Fig. 6 removes the dimensional structure diagram after test card for test paper disk in Fig. 5.
Fig. 7 is the schematic cross-sectional view in A-A faces in Fig. 6.
In figure, 1. bodies；2. pass in and out sample opening；3. display screen；4. microprocessor；5. lighting unit；6. shooting unit；7.
Graphics processing unit；8. laser；9. the first photoelectric sensor；10. test card；11. test paper disk；12. sample injection disc；13. neck；
14. rack；15. gear；16. motor；17. the second photoelectric sensor；18. catch；19. numbering；20. positioning through hole；21. positioning
Pin；22. sampling device.
Embodiment
The utility model is described in further detail below in conjunction with the drawings and specific embodiments.
Collaurum quantitative fluorescence analysis all-in-one as shown in Fig. 1~7, including body 1 and the turnover sample on body 1
Opening 2 and display screen 3；Provided with microprocessor 4 and the lighting unit 5 being connected with microprocessor 4, shooting unit 6, figure in body 1
As processing unit 7, the photoelectric sensor 9 of laser 8 and first；
Turnover sample opening 2 is used to being put into or taking out test card 10；
Lighting unit 5 is used to export illumination light to test card 10；
Shooting unit 6 is used to carry out optical pickup to test card 10 and draws shooting result；
Graphics processing unit 7 is used to analyze and process the shooting result of shooting unit 6, draws the nature controlling line of test card 10
Gray value and detection line gray value；
Laser 8 is used to carry out laser irradiation to test card 10, test card 10 is sent fluorescence；
First photoelectric sensor 9 is used to receive fluorescence and be processed as electric signal according to fluorescence intensity to send to microprocessor 4；
Microprocessor 4 is by calculating the ratio of nature controlling line gray value and detection line gray value or handling the first photoelectric sensor
9 electric signal draws testing result；
Display screen 3 is used to show testing result.
The sampling device 22 for being connected with microprocessor 4 and body 1 being stretched out by passing in and out sample opening 2 is additionally provided with body 1；Enter
Sampling device 22 includes the test paper disk 11 for being used to hold the level of multiple test cards 10 and entered for the level for fixing test paper disk 11
Sample dish 12；The upper surface of test paper disk 11 is provided with multiple necks 13 with the corresponding matching of test card 10；The bottom of sample injection disc 12 is provided with slide rail
(not shown), the side wall of sample injection disc 12 is provided with the rack 14 set along sidewall direction；The tooth coordinated with rack 14 is additionally provided with body 1
The motor 16 that wheel 15 and drive gear 15 are rotated；Motor 16 is connected with microprocessor 4；Lighting unit 5, shooting unit 6, laser
8 and first photoelectric sensor 9 directly over test paper disk 11.By the neck 13 that multiple test cards 10 are placed on to test paper disk 11
It is interior so that a test paper disk 11 can improve detection efficiency with the multiple test cards 10 of stationary arrangement；And pass through sample injection disc 12 and sample introduction
The effect of the rack 14 of the side wall of disk 12, gear 15 and motor 16, with Automated condtrol sample introduction and can go out sample, and sample introduction is stable, no
Test card 10 tilts the problems such as rocking caused by manual operation occurs.
The second photoelectric sensor 17 located at the both sides of sampling device 22 is additionally provided with body 1, test paper disk 11 is in each neck
13 sides are provided with the raised catch 18 for being used for cutting off the signal of the second photoelectric sensor 17, the second photoelectric sensor 17 and microprocessor
4 connections.Pass through the positioning action of the second photoelectric sensor 17 and catch 18 so that microprocessor 4 can effective controlled motor 16
Work, so that each displacement of sample injection disc 12 is limited in Test paper card 10 as the distance between two test cards 10,
So as to often detect a test card 10, sample injection disc 12, which moves forward, once causes next test card 10 to be in region to be detected.
Test card 10 is also divided into colloid gold test paper including being used on test paper disk 11 or on test card 10 that can be sticked
The identification code (not shown) of card or immunofluorescence test card.Identification code can be that Quick Response Code can also be coated with different colours
The scraps of paper；The identification code for representing colloidal gold test paper card is sticked in corresponding colloidal gold test paper card correspondence position by laboratory technician, will represent
The identification code of immunofluorescence test card is sticked position corresponding in corresponding immunofluorescence test card.Shooting unit 6 is to test card
In 10 shooting process, also by identification code shot and be uploaded to the progress of graphics processing unit 7 handle obtain the identification code correspondence
Information, microprocessor 4 judges the test card 10 for colloidal gold test paper card or immunofluorescence test card by the information, so as to enter
Row corresponding operating.
In addition, the upper surface of test paper disk 11 is provided with the numbering 19 for being used for identifying the neck 13 or mark in each side of neck 13
Label.By numbering 19 or label that correspondence neck 13 is set on test paper disk 11, in that context it may be convenient to record corresponding test card 10
Data, prevent data entanglement.
Test paper disk 11 and the removable connection of sample injection disc 12.By by test paper disk 11 and the removable connection of sample injection disc 12 so that
After test paper disk 11 is dismantled, the more convenient and quicker of test card 10 is placed.
Test paper disk 11 is provided with positioning through hole 20；Sample injection disc 12 is provided with the alignment pin 21 coordinated with positioning through hole 20.It is logical
The effect of alignment pin 21 and positioning through hole 20 is crossed, prevents the test paper disk 11 in moving process of sample injection disc 12 to be subjected to displacement with it.
Test card 10 is colloidal gold test paper card or immunofluorescence test card.
Pass through microprocessor 4 and connected lighting unit 5, shooting unit 6, graphics processing unit 7, the and of laser 8
The effect of first photoelectric sensor 9 so that all-in-one of the present utility model can both work as colloidal gold chart reader and use, and can work as again
Immunofluorescence analysis instrument is used, and saves cost, and only needs single injected sampling to can detect multiple test cards 10 for scribbling sample,
Test card 10 need not be distinguished for colloidal gold test paper card or immunofluorescence test card, experimental procedure is reduced, improve conventional efficient.
It should be pointed out that body 1 of the present utility model is provided with corresponding controlling switch button.
It is positioned in use, the test card 10 for scribbling sample is arranged in the neck 13 of test paper disk 11, and by test card 10
Made marks with corresponding numbering 19, be easy to record experimental result；Placed on test paper disk 11 after test card 10, test paper disk 11 is consolidated
Due on sample injection disc 12, and alignment pin 21 is coordinated with positioning through hole 20.When needing sample introduction, by being opened accordingly on body 1
Button is closed, the work of the controlled motor 16 of microprocessor 4 rotates so as to drive gear 15, and the rack 14 coordinated with it i.e. sample injection disc 12 enters
Sample, due to the effect of the second photoelectric sensor 17 and catch 18, sample injection disc 12 proceeds to relevant position；The control of microprocessor 4 is shone
Bright unit 5 exports illumination light to first test card 10 on test paper disk 11, and controls 6 pairs of the shooting unit test card 10 to carry out
Optical pickup, draws shooting result；Microprocessor 4 controls graphics processing unit 7 to analyze and process shooting result again, draws
The nature controlling line gray value of test card 10 and detection line gray value；Microprocessor 4 is by calculating nature controlling line gray value and detection line gray scale
The ratio of value draws testing result, and testing result is fed back into display screen 3 shown, microprocessor 4 controls electricity again afterwards
Machine 16 works, under the position-limiting action of the second photoelectric sensor 17 and catch 18, sample injection disc 12 move forward two test cards 10 away from
From so that second test card 10 on paper disc is in the illumination zone of lighting unit 5, is carried out successively.
If above-mentioned microprocessor 4 can not draw first by calculating the ratio of nature controlling line gray value and detection line gray value
The testing result of test card 10, then deducibility first test card 10 is dead card or immunofluorescence test card, then microprocessor
Device 4 controls laser 8 to carry out laser irradiation to test card 10, test card 10 is sent fluorescence；First photoelectric sensor 9 is received should
Fluorescence is simultaneously processed as electric signal and sent to microprocessor 4；Microprocessor 4 handles the electric signal and draws testing result, and will detection
As a result feed back to display screen 3 to be shown, carry out next test card 10 and detect；Carry out successively, until the examination on test paper disk 11
All detection is finished paper card 10, and the controlled motor 16 of microprocessor 4 works, and sample injection disc 12 is exited from turnover sample opening 2.
Claims (8)
1. a kind of collaurum quantitative fluorescence analysis all-in-one, it is characterised in that：Including body (1) and on the body (1)
Turnover sample opening (2) and display screen (3)；In the body (1) provided with microprocessor (4) and with the microprocessor (4) even
Lighting unit (5), shooting unit (6), graphics processing unit (7), laser (8) and the first photoelectric sensor (9) connect；
The turnover sample opening (2) is used to being put into or taking out test card (10)；
The lighting unit (5) is used to export illumination light to the test card (10)；
The shooting unit (6) is used to carry out optical pickup to the test card (10) and draws shooting result；
Described image processing unit (7) is used to analyze and process the shooting result of the shooting unit (6), draws test card
(10) nature controlling line gray value and detection line gray value；
The laser (8) is used to carry out laser irradiation to the test card (10), the test card (10) is sent fluorescence；
First photoelectric sensor (9) is used to receive the fluorescence and be processed as electric signal according to fluorescence intensity to send to described
Microprocessor (4)；
The microprocessor (4) is by calculating the ratio of nature controlling line gray value and detection line gray value or handling first photoelectricity
The electric signal of sensor (9) draws testing result；
The display screen (3) is used to show the testing result.
2. collaurum quantitative fluorescence analysis all-in-one according to claim 1, it is characterised in that：In the body (1) also
Provided with the sampling device that the body (1) is connected and stretched out by the turnover sample opening (2) with the microprocessor (4)
(22)；The sampling device (22) includes being used to hold the test paper disk (11) of the level of multiple test cards (10) and for solid
The sample injection disc (12) of the level of the fixed test paper disk (11)；Test paper disk (11) upper surface is provided with the multiple and test card
(10) neck (13) of corresponding matching；Sample injection disc (12) bottom is provided with slide rail, and sample injection disc (12) side wall is provided with along side wall side
To the rack (14) of setting；The gear (15) coordinated with the rack (14) is additionally provided with the body (1) and the tooth is driven
Take turns the motor (16) that (15) are rotated；The motor (16) is connected with the microprocessor (4)；The lighting unit (5), shooting are single
First (6), laser (8) and the first photoelectric sensor (9) are directly over the test paper disk (11).
3. collaurum quantitative fluorescence analysis all-in-one according to claim 2, it is characterised in that：In the body (1) also
Provided with the second photoelectric sensor (17) located at the sampling device (22) both sides, the test paper disk (11) is in each neck
(13) side is provided with the raised catch (18) for being used for cutting off the second photoelectric sensor (17) signal, second photoelectric sensing
Device (17) is connected with the microprocessor (4).
4. the collaurum quantitative fluorescence analysis all-in-one according to Claims 2 or 3, it is characterised in that：Also include being sticked
The test card (10) is divided into colloidal gold test paper card by being used on the test paper disk (11) or on the test card (10)
Or the identification code of immunofluorescence test card.
5. the collaurum quantitative fluorescence analysis all-in-one according to Claims 2 or 3, it is characterised in that：The test paper disk
(11) with the removable connection of the sample injection disc (12).
6. the collaurum quantitative fluorescence analysis all-in-one according to Claims 2 or 3, it is characterised in that：The test paper disk
(11) it is provided with positioning through hole (20)；The sample injection disc (12) is provided with the alignment pin coordinated with the positioning through hole (20)
(21)。
7. the collaurum quantitative fluorescence analysis all-in-one according to claim 1 or 2 or 3, it is characterised in that：The test card
(10) it is colloidal gold test paper card or immunofluorescence test card.
8. the collaurum quantitative fluorescence analysis all-in-one according to Claims 2 or 3, it is characterised in that：The test paper disk
(11) upper surface is provided with the numbering (19) or label for being used for identifying the neck (13) in each neck (13) side.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201720080690.5U CN206450598U (en) | 2017-01-22 | 2017-01-22 | Collaurum quantitative fluorescence analysis all-in-one |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720080690.5U CN206450598U (en) | 2017-01-22 | 2017-01-22 | Collaurum quantitative fluorescence analysis all-in-one |
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| Publication Number | Publication Date |
|---|---|
| CN206450598U true CN206450598U (en) | 2017-08-29 |
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ID=59667969
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| CN201720080690.5U Active CN206450598U (en) | 2017-01-22 | 2017-01-22 | Collaurum quantitative fluorescence analysis all-in-one |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106855515A (en) * | 2017-01-22 | 2017-06-16 | 武汉璟泓万方堂医药科技股份有限公司 | Collaurum quantitative fluorescence analysis all-in-one and its control method |
| CN109085147A (en) * | 2018-09-27 | 2018-12-25 | 湖南华南光电科技股份有限公司 | Propulsion analytic structure based on fluorescence sense technology trace explosive detector |
| CN111239026A (en) * | 2018-11-29 | 2020-06-05 | 肖光文 | Immune cell movement speed detection system |
| CN111795959A (en) * | 2020-07-24 | 2020-10-20 | 芯动森林(重庆)医疗科技有限公司 | Colloidal gold and fluorescence two-in-one data acquisition device and method |
| CN112725405A (en) * | 2021-01-27 | 2021-04-30 | 广州市胸科医院（广州市结核病防治所、广州市结核病治疗中心） | Drug sensitivity detection method for mycobacterium tuberculosis |
| CN113433105A (en) * | 2021-08-27 | 2021-09-24 | 深圳加美生物有限公司 | Fluorescent colloidal gold integrated detection and diagnosis instrument and method |
-
2017
- 2017-01-22 CN CN201720080690.5U patent/CN206450598U/en active Active
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106855515A (en) * | 2017-01-22 | 2017-06-16 | 武汉璟泓万方堂医药科技股份有限公司 | Collaurum quantitative fluorescence analysis all-in-one and its control method |
| CN106855515B (en) * | 2017-01-22 | 2023-11-24 | 武汉璟泓科技股份有限公司 | Colloid Jin Yingguang quantitative analysis integrated machine and control method thereof |
| CN109085147A (en) * | 2018-09-27 | 2018-12-25 | 湖南华南光电科技股份有限公司 | Propulsion analytic structure based on fluorescence sense technology trace explosive detector |
| CN111239026A (en) * | 2018-11-29 | 2020-06-05 | 肖光文 | Immune cell movement speed detection system |
| CN111795959A (en) * | 2020-07-24 | 2020-10-20 | 芯动森林(重庆)医疗科技有限公司 | Colloidal gold and fluorescence two-in-one data acquisition device and method |
| CN112725405A (en) * | 2021-01-27 | 2021-04-30 | 广州市胸科医院（广州市结核病防治所、广州市结核病治疗中心） | Drug sensitivity detection method for mycobacterium tuberculosis |
| CN113433105A (en) * | 2021-08-27 | 2021-09-24 | 深圳加美生物有限公司 | Fluorescent colloidal gold integrated detection and diagnosis instrument and method |
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| GR01 | Patent grant | ||
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Address after: 430000 No.18, East biopark Road, Donghu New Technology Development Zone, Wuhan City, Hubei Province Patentee after: Wuhan Jinghong Technology Co., Ltd Address before: 430075, No. 858, high-tech Avenue, Jiangxia District, Hubei, Wuhan, Optics Valley biological pharmaceutical base, two stage, A86-2 Patentee before: Wuhan Jinghong Wanfangtang Medical Technology Co., Ltd. |
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