CN206410910U - A kind of automatic preparation work station of standard liquid - Google Patents

A kind of automatic preparation work station of standard liquid Download PDF

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Publication number
CN206410910U
CN206410910U CN201720092459.8U CN201720092459U CN206410910U CN 206410910 U CN206410910 U CN 206410910U CN 201720092459 U CN201720092459 U CN 201720092459U CN 206410910 U CN206410910 U CN 206410910U
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China
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mechanical arm
work station
pipette tips
workbench
standard liquid
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CN201720092459.8U
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李鹏鑫
刘罡
刘罡一
陈勇
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Shanghai Analytic Medical Technology Co Ltd
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Shanghai Analytic Medical Technology Co Ltd
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Abstract

The utility model provides a kind of automatic preparation work station of standard liquid, including:The workbench of feature subregion, workbench is provided with mechanical arm, and mechanical arm is by drive device control, and the stroke of mechanical arm covers the functional areas on workbench;Liquid relief module, the liquid relief module is provided with dismountable disposable imbibition pipette tips;Control system, including user interface and microprocessor.The utility model automatically configures work station and sets different feature subregions on the table, liquid relief module is controlled to different subregions by mechanical arm, disposable imbibition pipette tips are abandoned in abandoned stope, the disposable pipette tips of different size are changed in consumptive material area, you can the replacing of disposable pipette tips is realized in control.Meanwhile, the utility model can automatically configure solution by plurality of reagents container according to concentration gradient.The utility model is simple in construction, and integration is strong, convenient easily to use, with very strong practicality.

Description

A kind of automatic preparation work station of standard liquid
Technical field
The utility model is related to the technical field for preparing solution, the automatic preparation work of specifically a kind of standard liquid Stand.
Background technology
Standard liquid refers to a series of solution of concentration knowns, is widely used in the quantitative analyses such as biochemical analysis, medical test. In quantitative analysis, by preparing a series of standard liquid of various concentrations, then pass through each standard liquid physics and chemistry of apparatus measures Property induction, and the standard curve between concentration is drawn, quantitatively detected to the concentration to unknown solution.Standard is molten The compound method of liquid is broadly divided into:Direct preparation method and standardization.Direct preparation method is first accurately to weigh quantitative primary standard substance, Constant volume turns into the standard liquid of actual concentrations after dissolving, and the standard liquid of low concentration can be diluted by the standard liquid of higher concentration Form.Standardization is for that can not be formulated directly into the standard liquid of actual concentrations, can first be configured to the concentration approximately needed, select Demarcated afterwards with primary standard substance, according to the amount of primary standard substance and be calibrated the volume that solution is spent, calculating is calibrated the dense of solution Degree.The preparation of traditional standard liquid is all based on both the above method, artificial to be completed using knockout or pipettor, configures Journey also needs to engineer's configuration flow and calculates dilution proportioning, and operating process is wasted time and energy, and due to personal operation technique And the error that exists of equipment used or operational error, the degree of accuracy and precision for causing standard liquid be not well positioned to meet reality Demand is tested, so as to largely effect on operating efficiency.Further, since some solution are poisonous and harmful volatile liquid, manually operated Journey has higher danger, and easily operating personnel's body is damaged.
In order to solve the above problems, existing commercially available mostly semi-automatic dilution configuration instrument passes through and connects high-precision syringe pump Or the conduit of peristaltic pump, hand-held conduit realizes point liquid and the dilution operation of solution in different reagent bottles.Commercially available is full-automatic molten Liquid dilutes instrument, then is to carry out imbibition and a point liquid by connecting the stainless pin of high-precision syringe pump or peristaltic pump, with being loaded with examination The round tray of agent bottle stand realizes the switching of reagent bottle by rotating.Above-mentioned instrument all needs user first during solution allocation Design configurations flow, and the amount of dilution and allocation proportion of various solution are set in instrument;And needed in configuration process to pipette tips Or the inside and outside wall of stainless pin is cleaned, residual solution will certainly also influence the degree of accuracy and the precision of solution;Operating efficiency Still it is not high.
The content of the invention
Main purpose of the present utility model is to provide a kind of the automatic of standard liquid in view of the shortcomings of the prior art to match somebody with somebody Work station processed, to realize that multiple standard liquids are prepared in automation, and prepares the degree of accuracy and the accuracy height of solution, operating efficiency It is high.
The utility model is achieved by the following technical solution:
A kind of automatic preparation work station of standard liquid, it is characterised in that:The work station includes:
The workbench of feature subregion, the top of workbench is provided with consumptive material area, the consumptive material area provided with some disposable Imbibition pipette tips, the right side of workbench is provided with the discarded box for being provided with abandoned stope, the abandoned stope and being used for placing imbibition pipette tips, work The bottom of platform, which is provided with reagent area, the reagent area, is provided with reagent container;
The workbench is provided with mechanical arm, and the mechanical arm is covered by drive device control, the stroke of the mechanical arm Functional areas on lid workbench;
The hand of the mechanical arm is connected with liquid relief module, and the liquid relief module is provided with dismountable disposable imbibition rifle Head;
Control system, including user interface and microprocessor.
It is preferred that, the liquid relief module is integrated liquid relief module.This can be achieved in integrated liquid relief module of the prior art Utility model, such as the hamilton ZEUS liquid relief modules of integrated Z axis control.
It is preferred that, the mechanical arm is times in cartesian co-ordinate type, circular cylindrical coordinate type, polar co-ordinate type, articulated manipulator It is a kind of.
It is furthermore preferred that the mechanical arm is two axle cartesian co-ordinate type mechanical arms, by orthogonal X-axis mechanical arm and Y-axis Mechanical arm is constituted.Using servomotor or stepper motor as drive device, using single shaft mechanical arm as groundwork unit, with ball wire Bar, synchronous belt, rack-and-pinion are conventional drive disk assembly, are realized by program control system and control and instruct to send, so that Realize the movement of mechanical arm.Mechanical arm is moved on the table, and it is all each that the liquid relief module of control hand, which is moved on workbench, Functional areas, complete to change disposable imbibition pipette tips, liquid relief, point liquid, piping and druming mixing and abandon the operation such as imbibition pipette tips.
It is preferred that, the user interface is touch-screen, and the microprocessor is single-chip microcomputer.User passes through touch-screen definable Solution parameter is set, and can in real time be shown during solution allocation and each module current operating conditions of monitoring station and solution Configuration flow.Single-chip microcomputer can generate solution allocation flow by setting program according to User Defined parameter Automated Design, Such as proportioning of the setting of transition solution, concentrate and dilution, the type selecting of pipette tips specification, and control liquid relief module and mechanical arm Related operational motion is carried out, replacing, imbibition/point liquid operation, piping and druming of such as liquid relief module to disposable pipette tips mix operation, machine Movement of the tool arm in sample stage difference in functionality area.
It is preferred that, the disposable imbibition pipette tips in the consumptive material area are arranged in arrays in pipette tips box.Disposable imbibition pipette tips It can be plurality of specifications model, such as 10 μ L, 50 μ L, 300 μ L, 1000 μ L, a kind of model rule are arranged with each pipette tips box The disposable imbibition pipette tips of lattice.
It is preferred that, the reagent container in the reagent area is from left to right divided into concentrate container, transition fluid by vertical setting of types Container, standard liquid container and solvent container.
The beneficial effects of the utility model are:
The utility model provides a kind of automatic preparation work station of standard liquid, and this automatically configures work station in workbench It is upper that different feature subregions are set, control liquid relief module to different subregions by mechanical arm, abandoned disposably in abandoned stope Imbibition pipette tips, the disposable pipette tips of different size are changed in consumptive material area, you can the replacing of disposable pipette tips is realized in control.Meanwhile, The utility model can automatically configure solution by plurality of reagents container according to concentration gradient.The letter of the utility model structure Single, integration is strong, convenient easily to use, with very strong practicality.
Brief description of the drawings
Fig. 1 is structural representation of the invention;
Fig. 2 is workbench schematic diagram of the invention;
Wherein, 1- workbench, 2-X shaft mechanicals arm, 3-Y shaft mechanicals arm, 4- liquid reliefs module, 5- pipette tips box, 6- discard box, 7- Concentrate container, 8- transition liquid container, 9- standards liquid container, 10- solvent containers.
Embodiment
The utility model is further illustrated by specific embodiment below in conjunction with accompanying drawing:Unreceipted tool in the following example The experimental method of concrete conditions in the establishment of a specific crime, conventionally and condition, or is selected according to catalogue.
As depicted in figs. 1 and 2, the automatic preparation work station of standard liquid of the present utility model includes the work of feature subregion Make platform 1, X-axis mechanical arm 2, Y-axis mechanical arm 3, liquid relief module 4 and control system (being not drawn into figure).Wherein, feature subregion The top of workbench 1, which is provided with consumptive material area, consumptive material area, is provided with some disposable imbibition pipette tips, and these disposable imbibition pipette tips are in matrix It is arranged in pipette tips box 5.The amount of the standard liquid configured as needed, can set disposable imbibition pipette tips for 10 μ L, 50 μ L, 300 μ L, 1000 μ L equal-specification models.The right side of workbench 1, which is provided with abandoned stope, abandoned stope to be provided with, to be used to place imbibition pipette tips Discarded box 6.By setting consumptive material area and abandoned stope, it is possible to achieve the replacing of disposable imbibition pipette tips.The bottom of workbench 1 is provided with Reagent container is provided with reagent area, reagent area, reagent container is from left to right divided into concentrate container 7, transition fluid by vertical setting of types Container 8, standard liquid container 9 and solvent container 10, are respectively used to deposit the stepped concentrate of concentration, transition fluid, titer And solvent.
X-axis mechanical arm 2 and Y-axis mechanical arm 3 are by drive device control, using servomotor as drive device, with single shaft machine Tool arm is groundwork unit, using rack-and-pinion as drive disk assembly, is realized and controlled and instruction transmission by program control system, from And realize the movement of X-axis mechanical arm 2 and Y-axis mechanical arm 3.The hand of X-axis mechanical arm 2 and Y-axis mechanical arm 3 is connected with liquid relief module 4, liquid relief module 4 is provided with dismountable disposable imbibition pipette tips.By the stroke for ensureing X-axis mechanical arm 2 and Y-axis mechanical arm 3 All functional areas on workbench 1 can be covered, so that liquid relief module 4 can be moved to all regions, disposable inhale are completed The action such as the replacing of liquid pipette tips and the liquid relief of solution, point liquid.Control system includes touch-screen and single-chip microcomputer, logical with drive device Cross electrical connection.
In use, first, operating personnel join first by touch-screen input data to the related of preparation of solution Number is defined.Selection (such as methanol, acetonitrile, serum) including concentrate, selection (such as deionized water, PBS of type of solvent Deng), then self-defined concentrate concentration, the concentration of standard liquid and required volume.If the sample used in work station no user is molten Liquid type, then can be modified based on solution parameter close in work station to parameters such as imbibition/point liquid fair curve, speed And verify, chosen again after setting up new solution type.Then start the work station design phase, by program Automated Design simultaneously Preparation program is generated, includes the series and concentration of transition fluid, standard liquid, concentrate, the volume of transition fluid and solvent, each The selection of disposable pipette tips specification in imbibition/point liquid operating process, the aggregate demand volume and all kinds of solution of concentrate and solvent Arrangement demand of reagent bottle etc., then output display preparation program on the touchscreen.Then operating personnel carry according to touch-screen Show, confirm after the preparation program, then carry out the preparation of concentrate, dilution, disposable pipette tips and reagent bottle, and be placed into corresponding Position.Start work station, work station proceeds by automation, one-stop solution process for preparation, to X-axis mechanical arm 2 and Y-axis Mechanical arm 3 carries out instruction control liquid relief module 4 and moved on workbench 1, and specific control action includes:Mechanical arm and liquid relief module Loading/discarding of imbibition pipette tips, liquid relief/point liquid, piping and druming are mixed in 4 position initialization, liquid relief module 4.Simultaneously in work station In running, touch-screen shows and monitored in real time the running status and configuration flow of each module.Finally, operating personnel are that can use Go out the standard liquid configured, while being preserved and being printed to configuration flow, and laboratory information pipe can be transferred data to In reason system, it is easy to the traceability of experimental data.
Detailed description above is only the explanation of the preferred embodiment of the utility model, and non-therefore limitation is of the present utility model specially Sharp scope, so, all equivalence techniques changes with carried out by this creation specification and diagramatic content are both contained in the utility model The scope of the claims in.

Claims (7)

1. a kind of automatic preparation work station of standard liquid, it is characterised in that:The work station includes:
The workbench of feature subregion, the top of workbench, which is provided with consumptive material area, the consumptive material area, is provided with some disposable imbibitions Pipette tips, the right side of workbench is provided with the discarded box for being provided with abandoned stope, the abandoned stope and being used for placing imbibition pipette tips, workbench Bottom, which is provided with reagent area, the reagent area, is provided with reagent container;
The workbench is provided with mechanical arm, and the mechanical arm passes through drive device control, the stroke covering work of the mechanical arm Make the functional areas on platform;
The hand of the mechanical arm is connected with liquid relief module, and the liquid relief module is provided with dismountable disposable imbibition pipette tips;
Control system, including user interface and microprocessor.
2. the automatic preparation work station of standard liquid according to claim 1, it is characterised in that:The liquid relief module is collection Into liquid relief module.
3. the automatic preparation work station of standard liquid according to claim 1, it is characterised in that:The mechanical arm is right angle Any of coordinate type, circular cylindrical coordinate type, polar co-ordinate type, articulated manipulator.
4. the automatic preparation work station of standard liquid according to claim 3, it is characterised in that:The mechanical arm is two axles Cartesian co-ordinate type mechanical arm, is made up of orthogonal X-axis mechanical arm and Y-axis mechanical arm.
5. the automatic preparation work station of standard liquid according to claim 1, it is characterised in that:The consumptive material area is once Property imbibition pipette tips are arranged in arrays in pipette tips box.
6. the automatic preparation work station of standard liquid according to claim 1, it is characterised in that:Examination in the reagent area Agent container is from left to right divided into concentrate container, transition liquid container, standard liquid container and solvent container by vertical setting of types.
7. the automatic preparation work station of standard liquid according to claim 1, it is characterised in that:The user interface is tactile Screen is touched, the microprocessor is single-chip microcomputer.
CN201720092459.8U 2017-01-24 2017-01-24 A kind of automatic preparation work station of standard liquid Active CN206410910U (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106840797A (en) * 2017-01-24 2017-06-13 上海析维医疗科技有限公司 The automatic preparation work station and compound method of a kind of standard liquid
CN107768694A (en) * 2017-08-29 2018-03-06 成都安普利菲能源技术有限公司 Accurate Qu Ye mechanisms and method and accurate fluid body and method
CN109201133A (en) * 2018-11-13 2019-01-15 望潮科技(北京)有限公司 A kind of mechanical arm experimental system
CN114675018A (en) * 2022-03-29 2022-06-28 中山大学孙逸仙纪念医院 Antibody reagent blending equipment

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106840797A (en) * 2017-01-24 2017-06-13 上海析维医疗科技有限公司 The automatic preparation work station and compound method of a kind of standard liquid
CN107768694A (en) * 2017-08-29 2018-03-06 成都安普利菲能源技术有限公司 Accurate Qu Ye mechanisms and method and accurate fluid body and method
CN109201133A (en) * 2018-11-13 2019-01-15 望潮科技(北京)有限公司 A kind of mechanical arm experimental system
CN114675018A (en) * 2022-03-29 2022-06-28 中山大学孙逸仙纪念医院 Antibody reagent blending equipment

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