CN206304727U - A kind of DL proline synthesis reactor - Google Patents
A kind of DL proline synthesis reactor Download PDFInfo
- Publication number
- CN206304727U CN206304727U CN201621287400.6U CN201621287400U CN206304727U CN 206304727 U CN206304727 U CN 206304727U CN 201621287400 U CN201621287400 U CN 201621287400U CN 206304727 U CN206304727 U CN 206304727U
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- China
- Prior art keywords
- tank body
- central siphon
- cold
- hot water
- agitating shaft
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Abstract
The utility model discloses a kind of DL proline synthesis reactor, including tank body, kettle top, bottom, cold and hot water layer, cast hopper, servomotor, agitating shaft, axle side opening, central siphon, centrifugal network, circulating pump, discharge nozzle；The tank body lower part is provided with bottom, cold and hot water layer is provided between the tank body and bottom, the kettle top is concentric with cold and hot water layer to be provided with the agitating shaft driven by servomotor, the double-deck centrifugal network of upper opening type is provided with the middle of the agitating shaft, the agitating shaft of part is set using central siphon under the centrifugal network, central siphon in the centrifugal network is provided with multiple axle side openings, and the central siphon is opened in the chamber of bottom, and the central siphon lower end is solvent mouthful；Rectangle stirring slurry and circular stirring slurry are provided with outside the central siphon, the bottom lower section is provided with discharging opening；This new racemization for producing DL proline, separation, cleaning are integrated in a reactor, reduce preparation process, and improve production efficiency, DL proline fine work quality is good, reduces production cost.
Description
Technical field
The utility model is related to a kind of DL-proline production technology apparatus field, more particularly to a kind of DL-proline synthesis
Reactor.
Background technology
DL-proline is a kind of white crystals or crystalline powder；Micro- smelly, taste is micro- sweet.This product is readily soluble in water, in ethanol
Middle dissolving, it is insoluble in ether or n-butanol.Chemical formula：C5H9NO2；It is in food and medicine field, particularly nutriment addition
Agent and medical material medicine field are all widely used.As the raw material DL-proline of nourishing additive agent in all kinds of nutriment, portion
Divide aspect all realizable values such as drinks.L-amino acid is used as lactam antibiotics in vital movement and medicine preparation
Intermediate there is irreplaceable status；And DL-proline has turned into the primary raw material intermediate of some antibiotics,
Its derivative also play suitable effect in anticancer aspect.
The preparation method of traditional DL-proline is：L- dried meat ammonia is added in reaction system of the organic acid as solvent
Acid, the racemization for realizing proline as catalyst using aldehyde compound, need centrifugation to obtain DL-proline crude product after racemization,
Refining solvent is used as by ethanol or methyl alcohol again and prepares DL-proline certified products.
It is of the prior art to have the disadvantage DL-proline complex manufacturing, low production efficiency.
Utility model content
In order to solve the above technical problems, the utility model provides a kind of DL-proline synthesis reaction vessel, for existing skill
Deficiency in art, designs compound reactor, and racemization, separation, cleaning are integrated in a reactor, reduces preparation process,
Improve production efficiency, DL-proline fine work quality is good.
To reach above-mentioned purpose, the technical solution of the utility model is as follows：A kind of DL-proline synthesis reaction vessel, including
Tank body, kettle top, bottom, cold and hot water layer, cast hopper, servomotor, agitating shaft, axle side opening, central siphon, centrifugal network, rectangle stirring slurry,
Circular stirring slurry, circulating pump, pipeline, magnetic valve, water pipe, liquid material pipe, discharge nozzle, thermometer, PH meters, solvent mouthful, its feature exist
In：
The tank body is the stainless steel drum-shaped housing with plane kettle top, and the tank body lower part is provided with semicircle kettle
Bottom, sealing is provided with cold and hot water layer between the tank body and bottom, and the kettle top passes through seal shaft with cold and hot water layer center
Set is turnable to be provided with agitating shaft, and the agitating shaft is rotated by the servomotor bi-directional drive on kettle top, in the agitating shaft
Between position be welded and fixed the double-deck centrifugal network for being provided with upper opening type, the agitating shaft of part is set using central siphon under the centrifugal network
Put, multiple axle side openings are provided with the central siphon in the centrifugal network, the central siphon is opened on bottom chamber through the cold and hot water layer
Interior, the central siphon lower end is solvent mouthful；Staggeredly welding is fixedly installed rectangle stirring slurry and circular stirring slurry for the central siphon outside,
The bottom lower section is provided with discharging opening.
Relative direction is provided with water pipe and liquid material pipe on the kettle top, and the tank body side surface upper part is provided with feeding intake for taper
Bucket.
The cold and hot water layer is connected by pipeline with cold water, hot water pipeline, and by feed liquid in cold and hot water management tank body
Temperature.
The tank body side lower is provided with thermometer and PH meters, the temperature of feed liquid in the thermometer and PH meter detection tank bodies
Degree and pH value.
The tank body, bottom are connected with circulating pump by pipeline by magnetic valve respectively, and the outlet of the circulating pump passes through
Pipeline is connected to the top of the tank body, and is opened on the top of centrifugal network.
Operation principle of the present utility model is：One direction of the servomotor drives agitating shaft to play the work of stirring liquid material
With another direction can at a high speed rotarily drive centrifugal network and liquid material is centrifuged；The centrifugal network not double-decker, interlayer
Interior centrifugate is flowed into the chamber of bottom by axle side opening, after the completion of liquid material racemization, is pumped into centrifugal network by circulation, is separated
Solvent out is sent out by bottom chamber and recycled；Reagent or rinse water can be added by water pipe or liquid material pipe, it is right
DL-proline crude product in centrifugal network is cleaned；Further, refined operation is carried out to crude product by ethanol.
By above-mentioned technical proposal, the beneficial effect of technical solutions of the utility model is：Compound reactor is designed, will be disappeared
Rotation, separation, cleaning are integrated in a reactor, reduce preparation process, and improve production efficiency, DL-proline fine work quality is good；
Production process equipment has been simplified, production cost has been reduced.
Brief description of the drawings
In order to illustrate more clearly of the utility model embodiment or technical scheme of the prior art, below will be to embodiment
Or the accompanying drawing to be used needed for description of the prior art is briefly described, it should be apparent that, drawings in the following description are only
It is some embodiments of the present utility model, for those of ordinary skill in the art, is not paying the premise of creative work
Under, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is a kind of DL-proline synthesis reaction vessel schematic diagram disclosed in the utility model embodiment.
Numeral and the corresponding component title represented by letter in figure：
1. the cold and hot water layer in 2. kettle top of tank body, 3. bottom 4.
5. the axle side opening of 6. servomotor of cast hopper, 7. agitating shaft 8.
9. the circular stirring slurry of 10. centrifugal network of central siphon, 11. rectangle stirring slurry 12.
The water pipe of 13. circulating pump, 14. pipeline, 15. magnetic valve 16.
The thermometer 20.PH of 17. liquid material pipe, 18. discharge nozzle 19. is counted
21. solvents mouthful
Specific embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the utility model embodiment is carried out
Clearly and completely describe, it is clear that described embodiment is only a part of embodiment of the utility model, rather than whole
Embodiment.Based on the embodiment in the utility model, those of ordinary skill in the art are not under the premise of creative work is made
The every other embodiment for being obtained, belongs to the scope of the utility model protection.
According to Fig. 1, the utility model provides a kind of DL-proline synthesis reaction vessel, including tank body 1, kettle top 2, bottom
3rd, cold and hot water layer 4, cast hopper 5, servomotor 6, agitating shaft 7, axle side opening 8, central siphon 9, centrifugal network 10, rectangle stirring slurry 11, circle
Shape stirring slurry 12, circulating pump 13, pipeline 14, magnetic valve 15, water pipe 16, liquid material pipe 17, discharge nozzle 18, thermometer 19, PH meter 20,
Solvent mouthful 21.
The tank body 1 is the stainless steel drum-shaped housing with plane kettle top 2, and the bottom of the tank body 1 is provided with semicircle
Bottom 3, sealing is provided with cold and hot water layer 4 between the tank body 1 and bottom 3, and the kettle top 2 is logical with the center of cold and hot water layer 4
Cross sealing axle sleeve and be turnably provided with agitating shaft 7, the agitating shaft 7 is rotated by the bi-directional drive of servomotor 6 on kettle top 2,
The centre position of the agitating shaft 7 is welded and fixed and is provided with double-deck centrifugal network 10 of upper opening type, 10 times parts of the centrifugal network
Agitating shaft 7 is set using central siphon 9, and multiple axle side openings 8 are provided with the central siphon 10 in the centrifugal network 10, and the central siphon 9 is passed through
The cold and hot water layer 4 is opened in the chamber of bottom 3, and the lower end of the central siphon 9 is solvent mouthful 21；Staggeredly weld solid in the outside of the central siphon 9
Surely rectangle stirring slurry 11 and circular stirring slurry 12 are provided with, the lower section of the bottom 3 is provided with discharging opening 18.
Relative direction is provided with water pipe 16 and liquid material pipe 17 on the kettle top 2, and the side surface upper part of the tank body 1 is provided with taper
Cast hopper 5.
The cold and hot water layer 4 is connected by pipeline with cold water, hot water pipeline, and by feed liquid in cold and hot water management tank body 1
Temperature.
The side lower of the tank body 1 is provided with thermometer 19 and PH meters 20, and the thermometer 19 and PH meters 20 detect tank body 1
The temperature and pH value of interior feed liquid.
The tank body 1, bottom 3 are connected with circulating pump 13 by pipeline 14 by magnetic valve 15 respectively, the circulating pump 13
Outlet the top of the tank body 1 is connected to by pipeline 14, and be opened on the top of centrifugal network 10.
Concrete operation step of the present utility model is：First pass through cast hopper 5 to add materials, add organic by liquid material pipe 17
Sour solvent, is heated by cold and hot water layer 4 to liquid material, rises high-temperature, is opened servomotor 6 and is driven agitating shaft 7 to rotate, described
6 one directions of servomotor drive agitating shaft 7 to play a part of to stir liquid material, and another direction can at a high speed rotarily drive centrifugal network
10 pairs of liquid materials are centrifuged；Racemization operation is carried out to L-PROLINE according to manufacturing condition；After the completion of racemization, carry out from
The heart is separated, and the centrifugal network 10 is double-decker, and the centrifugate in interlayer is flowed into the chamber of bottom 3 by axle side opening 8, liquid material racemization
After the completion of, it is transported in centrifugal network 10 by circulating pump 13, the solvent separated is sent out by the chamber of bottom 3 and recycled；It is logical
Crossing water pipe 16 or liquid material pipe 17 can add reagent or rinse water, and the DL-proline crude product in centrifugal network 10 is carried out clearly
Wash；Further, refined operation is carried out to crude product by ethanol.
By above-mentioned specific embodiment, the beneficial effects of the utility model are：Compound reactor is designed, by racemization, is divided
It is integrated in a reactor from, cleaning, reduces preparation process, improve production efficiency, DL-proline fine work quality is good；Simplify
Production process equipment, reduces production cost.
The foregoing description of the disclosed embodiments, enables professional and technical personnel in the field to realize or new using this practicality
Type.Various modifications to these embodiments will be apparent for those skilled in the art, determine herein
The General Principle of justice can in other embodiments be realized in the case where spirit or scope of the present utility model are not departed from.Cause
This, the utility model is not intended to be limited to the embodiments shown herein, and is to fit to and principles disclosed herein
The most wide scope consistent with features of novelty.
Claims (5)
1. a kind of DL-proline synthesis reaction vessel, it is characterised in that including tank body, kettle top, bottom, cold and hot water layer, cast hopper,
Servomotor, agitating shaft, axle side opening, central siphon, centrifugal network, rectangle stirring slurry, circular stirring slurry, circulating pump, pipeline, magnetic valve,
Water pipe, liquid material pipe, discharge nozzle, thermometer, PH meters, solvent mouthful；The tank body is the stainless steel drum-shaped shell with plane kettle top
Body, the tank body lower part is provided with semicircle bottom, and sealing is provided with cold and hot water layer, the kettle top between the tank body and bottom
Agitating shaft, the servo electricity that the agitating shaft passes through kettle top are turnably provided with by sealing axle sleeve with cold and hot water layer center
Machine bi-directional drive rotates, and the agitating shaft centre position is welded and fixed the double-deck centrifugal network for being provided with upper opening type, the centrifugation
The agitating shaft of part off the net is set using central siphon, and multiple axle side openings are provided with the central siphon in the centrifugal network, and the central siphon is worn
Cross the cold and hot water layer to be opened in the chamber of bottom, the central siphon lower end is solvent mouthful；The central siphon outside is staggeredly welded and fixed and sets
Rectangle stirring slurry and circular stirring slurry are equipped with, the bottom lower section is provided with discharging opening.
2. a kind of DL-proline synthesis reaction vessel according to claim 1, it is characterised in that contra on the kettle top
To water pipe and liquid material pipe is provided with, the tank body side surface upper part is provided with the cast hopper of taper.
3. a kind of DL-proline synthesis reaction vessel according to claim 1, it is characterised in that the cold and hot water layer passes through
Pipeline is connected with cold water, hot water pipeline, and by the temperature of feed liquid in cold and hot water management tank body.
4. a kind of DL-proline synthesis reaction vessel according to claim 1, it is characterised in that the tank body side lower
Thermometer and PH meters are provided with, the temperature and pH value of feed liquid in the thermometer and PH meter detection tank bodies.
5. a kind of DL-proline synthesis reaction vessel according to claim 1, it is characterised in that the tank body, bottom difference
Connected by magnetic valve with circulating pump by pipeline, the outlet of the circulating pump is connected to the top of the tank body by pipeline,
And it is opened on the top of centrifugal network.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621287400.6U CN206304727U (en) | 2016-11-28 | 2016-11-28 | A kind of DL proline synthesis reactor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621287400.6U CN206304727U (en) | 2016-11-28 | 2016-11-28 | A kind of DL proline synthesis reactor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206304727U true CN206304727U (en) | 2017-07-07 |
Family
ID=59249650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621287400.6U Expired - Fee Related CN206304727U (en) | 2016-11-28 | 2016-11-28 | A kind of DL proline synthesis reactor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206304727U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111804256A (en) * | 2020-06-18 | 2020-10-23 | 宁波南大光电材料有限公司 | Acrylic acid monomer washing kettle |
-
2016
- 2016-11-28 CN CN201621287400.6U patent/CN206304727U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111804256A (en) * | 2020-06-18 | 2020-10-23 | 宁波南大光电材料有限公司 | Acrylic acid monomer washing kettle |
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170707 Termination date: 20171128 |