CN206295895U - Automation pharmaceutical synthesis privacy protection gas mixing apparatus - Google Patents

Automation pharmaceutical synthesis privacy protection gas mixing apparatus Download PDF

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Publication number
CN206295895U
CN206295895U CN201621341609.6U CN201621341609U CN206295895U CN 206295895 U CN206295895 U CN 206295895U CN 201621341609 U CN201621341609 U CN 201621341609U CN 206295895 U CN206295895 U CN 206295895U
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CN
China
Prior art keywords
tank body
appendix
reactor tank
stomata
mixing apparatus
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Active
Application number
CN201621341609.6U
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Chinese (zh)
Inventor
梁彬
田单
李远智
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SICHUAN MOLCAN BIOLOGICAL PHARMACEUTICAL CO., LTD.
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Chengdu Moer Biopharmaceutical Co Ltd
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Priority to CN201621341609.6U priority Critical patent/CN206295895U/en
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Abstract

The utility model discloses one kind automation pharmaceutical synthesis privacy protection gas mixing apparatus, including lid, reactor tank body, it is inclined-plane at the opening of the reactor tank body, reactor tank body bottom connects with breather chamber, air inlet is provided with the breather chamber, hopper is connected with lid, hopper bottom is provided with electronic scale, magnetic valve is provided with electronic scale, the hopper is provided with tripper, reactor tank body top is provided with blast pipe, reactor tank body bottom is provided with discharge nozzle, blast pipe is connected with one end of appendix one, the other end of appendix one is connected with air accumulator, air accumulator is provided with appendix two, appendix two is connected with air inlet, the blast pipe is provided with filter, air valve is equipped with the appendix one and appendix two.The utility model high degree of automation, resource can cycling and reutilization, mixture homogeneity is high, and high working efficiency is reliable and stable.

Description

Automation pharmaceutical synthesis privacy protection gas mixing apparatus
Technical field
The utility model belongs to organic synthesis apparatus field, more particularly to automates pharmaceutical synthesis privacy protection gas and mixes Conjunction equipment.
Background technology
Need first to be sufficiently stirred for feed components during pharmaceutical synthesis, it is stirred, typically adopt at present It is stirred with the agitator with agitating shaft, because pharmaceutical synthesis are all more strict to all requirements, particularly to environment It is required that higher, most of synthetic reactions are completed under nitrogen or inert gas shielding, to prevent reaction during with oxygen Contact, needs to be passed through protective gas while stirring, and to prevent other reactions from occurring, practical operation is complex;And stir Portable bacterium on device is mixed, uncertain factor is more, is easily caused drug contamination, while artificial operation is needed between each link, automatically Change low degree, and significantly increase the probability of drug contamination.
Utility model content
The purpose of this utility model is:To overcome the shortcomings of the existing technology, providing a kind of high degree of automation, resources circulation Recycle, be sufficiently mixed uniform, high working efficiency, reliable and stable automation pharmaceutical synthesis privacy protection gas mixing apparatus.
To achieve the above object, the technical solution of the utility model is:
Automation pharmaceutical synthesis privacy protection gas mixing apparatus, including lid, reactor tank body, the reactor tank body Opening at be inclined-plane, reactor tank body bottom connected with breather chamber, and air inlet is provided with the breather chamber, is connected with lid Hopper, hopper bottom is provided with electronic scale, and magnetic valve is provided with electronic scale, and the hopper is provided with tripper, in reactor tank body Portion is provided with blast pipe, and reactor tank body bottom is provided with discharge nozzle, and blast pipe is connected with one end of appendix one, appendix one it is another One end is connected with air accumulator, and air accumulator is provided with appendix two, and appendix two is connected with air inlet, and the blast pipe was provided with Air valve is equipped with filter, the appendix one and appendix two, the bottom surface of the reactor tank body is provided with some for leading to First stomata of protective gas, first stomata is circular hole, and a circle is provided with around the first stomata for leading to the of protective gas Two stomatas, second stomata is inclined hole, and the angle between the second stomata incline direction and vertical direction is 30~45 °.
Further, reactor tank body side wall is provided with the stomata of a circle the 3rd.
Further, it is additionally provided with photoscope on the wall of the reactor tank body side.
Further, the first stomata and the second stomata are vertical hole, and the 3rd stomata is transverse holes.
Further, protective gas uses nitrogen.
As a result of such scheme, the beneficial effects of the utility model are:
1st, the utility model high degree of automation, improves operating efficiency, reduces cost of labor, reduce each link it Between drug contamination possibility, quantitatively mixed using electronic scale, error is reduced, by being passed directly into protective gas to reactant Mixed, be sufficiently mixed uniformly, mixing efficiency is high, reliable and stable, while as the protection in organic synthesis and mixing Close, operation is very simple, and mix under anaerobic aseptic condition, be prevented effectively from reactant pollution and other reactions occur;
2nd, air accumulator is provided with, impurity is filtered out by filter, be passed through in air accumulator, protective gas can be reclaimed and followed again Ring is used, and is economized on resources, reduces cost;
3rd, using the first vertical stomata, the second oblique stomata is stirred mixing to reactant from all directions, makes Reactant is fully mixed, and mixing efficiency is high, and mixture homogeneity is high, and oblique stomata can allow reactant around reactor tank body Center is stirred uniformly in the same direction;
4th, reactor tank body side wall is provided with the 3rd horizontal stomata of a circle, and the 3rd stomata is horizontal inclined hole, energy It is enough that secondary mixing is carried out to reactant, make its mixture homogeneity higher;
5th, photoscope is additionally provided with the wall of the reactor tank body side, it can be seen that in reactor tank body during mixing Situation, once going wrong, can timely take appropriate measures;
6th, the sealing structure of multi-step is employed on lid, then good airproof performance, effectively prevent the pollution in production.
Brief description of the drawings
Fig. 1 is structural representation of the present utility model.
Fig. 2 is the structural representation of reactor tank body.
Fig. 3 is the front view of reactor tank body bottom surface.
Reference:1- reactor tank bodies, 2- electronic scales, 3- magnetic valves, 4- hoppers, 5- trippers, 6- breather chambers, 7- enters Gas port, 8- blast pipes, 9- filters, 10- discharge nozzles, 11- air valves, 12- appendixs one, 13- air accumulators, 14- lids, 15- One stomata, the stomatas of 16- second, the stomatas of 17- the 3rd, 18- photoscopes, 19- appendixs two.
Specific embodiment
Embodiment 1:With reference to Fig. 1, Fig. 2, Fig. 3, pharmaceutical synthesis privacy protection gas mixing apparatus, including lid are automated 14th, reactor tank body 1, is inclined-plane at the opening of the reactor tank body 1, and the bottom of reactor tank body 1 connects with breather chamber 6, institute State and be provided with air inlet 7 in breather chamber 6, hopper 4 is connected with lid 14, the bottom of hopper 4 is provided with electronic scale 2, and electronic scale 2 can be accurate True quantitative required component, proportioning is more accurate, and magnetic valve 3 is provided with electronic scale 2, and the hopper 4 is provided with tripper 5, point Glassware 5 can carry out multi-component distribution, improve operating efficiency, and the top of reactor tank body 1 is provided with blast pipe 8, under reactor tank body 1 Portion is provided with discharge nozzle 10, and blast pipe 8 is connected with one end of appendix 1, and the other end and the air accumulator 13 of appendix 1 connect Connect, air accumulator 13 is provided with appendix 2 19, appendix 2 19 is connected with air inlet 7, and the blast pipe 8 is provided with filter 9, Air valve 11 is equipped with the appendix 1 and appendix 2 19, the bottom surface of the reactor tank body 1 is provided with some being used for First stomata 15 of logical protective gas, first stomata 15 is circular hole, a circle is provided with around the first stomata 15 and is protected for logical Second stomata 16 of gas, second stomata 16 is inclined hole, the angle between the incline direction of the second stomata 16 and vertical direction It is 30~45 °.
Photoscope 18 is additionally provided with the wall of the side of reactor tank body 1 described in the present embodiment.
The first stomata 15 and the second stomata 16 are vertical hole in the present embodiment.
Protective gas uses nitrogen in the present embodiment, and the component according to each pharmaceutical synthesis may be selected other protective gas.
Embodiment 2:With reference to Fig. 1, Fig. 2, Fig. 3, pharmaceutical synthesis privacy protection gas mixing apparatus, including lid are automated 14th, reactor tank body 1, is inclined-plane at the opening of the reactor tank body 1, and the bottom of reactor tank body 1 connects with breather chamber 6, institute State and be provided with air inlet 7 in breather chamber 6, hopper 4 is connected with lid 14, the bottom of hopper 4 is provided with electronic scale 2, and electronic scale 2 can be accurate True quantitative required component, proportioning is more accurate, and magnetic valve 3 is provided with electronic scale 2, and the hopper 4 is provided with tripper 5, point Glassware 5 can carry out multi-component distribution, improve operating efficiency, and the top of reactor tank body 1 is provided with blast pipe 8, under reactor tank body 1 Portion is provided with discharge nozzle 10, and blast pipe 8 is connected with one end of appendix 1, and the other end and the air accumulator 13 of appendix 1 connect Connect, air accumulator 13 is provided with appendix 2 19, appendix 2 19 is connected with air inlet 7, and the blast pipe 8 is provided with filter 9, Air valve 11 is equipped with the appendix 1 and appendix 2 19, the bottom surface of the reactor tank body 1 is provided with some being used for First stomata 15 of logical protective gas, first stomata 15 is circular hole, a circle is provided with around the first stomata 15 and is protected for logical Second stomata 16 of gas, second stomata 16 is inclined hole, the angle between the incline direction of the second stomata 16 and vertical direction It is 30~45 °.The side of reactor tank body 1 described in the present embodiment wall is provided with the stomata 17 of a circle the 3rd.
Photoscope 18 is additionally provided with the wall of the side of reactor tank body 1 described in the present embodiment.
The first stomata 15 and the second stomata 16 are vertical hole in the present embodiment, and the 3rd stomata 17 is transverse holes.
Protective gas uses nitrogen in the present embodiment.Component according to each pharmaceutical synthesis may be selected other protective gas, root Other protective gas may be selected according to the component of each pharmaceutical synthesis.

Claims (5)

1. pharmaceutical synthesis privacy protection gas mixing apparatus are automated, it is characterised in that:Including lid(14), reactor tank body (1), the reactor tank body(1)Opening at be inclined-plane, reactor tank body(1)Bottom and breather chamber(6)Connection, the ventilation Room(6)In be provided with air inlet(7), lid(14)On be connected with hopper(4), hopper(4)Bottom is provided with electronic scale(2), electronic scale (2)In be provided with magnetic valve(3), the hopper(4)It is provided with tripper(5), reactor tank body(1)Top is provided with blast pipe(8), Reactor tank body(1)Bottom is provided with discharge nozzle(10), blast pipe(8)With appendix one(12)One end connection, appendix one (12)The other end and air accumulator(13)Connection, air accumulator(13)It is provided with appendix two(19), appendix two(19)With air inlet Mouthful(7)Connection, the blast pipe(8)It is provided with filter(9), the appendix one(12)With appendix two(19)On be equipped with Air valve(11), the reactor tank body(1)Bottom surface be provided with some the first stomatas for leading to protective gas(15), described One stomata(15)It is circular hole, the first stomata(15)Surrounding is provided with a circle for leading to the second stomata of protective gas(16), described Two stomatas(16)It is inclined hole, the second stomata(16)Angle between incline direction and vertical direction is 30~45 °.
It is 2. according to claim 1 to automate pharmaceutical synthesis privacy protection gas mixing apparatus, it is characterised in that:It is described anti- Answer kettle tank body(1)Side wall is provided with the stomata of a circle the 3rd(17).
It is 3. according to claim 1 to automate pharmaceutical synthesis privacy protection gas mixing apparatus, it is characterised in that:It is described anti- Answer kettle tank body(1)Photoscope is additionally provided with the wall of side(18).
It is 4. according to claim 1 to automate pharmaceutical synthesis privacy protection gas mixing apparatus, it is characterised in that:First gas Hole(15)With the second stomata(16)It is vertical hole, the 3rd stomata(17)It is transverse holes.
It is 5. according to claim 1 to automate pharmaceutical synthesis privacy protection gas mixing apparatus, it is characterised in that:Protection gas Body uses nitrogen.
CN201621341609.6U 2016-12-08 2016-12-08 Automation pharmaceutical synthesis privacy protection gas mixing apparatus Active CN206295895U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201621341609.6U CN206295895U (en) 2016-12-08 2016-12-08 Automation pharmaceutical synthesis privacy protection gas mixing apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201621341609.6U CN206295895U (en) 2016-12-08 2016-12-08 Automation pharmaceutical synthesis privacy protection gas mixing apparatus

Publications (1)

Publication Number Publication Date
CN206295895U true CN206295895U (en) 2017-07-04

Family

ID=59212122

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201621341609.6U Active CN206295895U (en) 2016-12-08 2016-12-08 Automation pharmaceutical synthesis privacy protection gas mixing apparatus

Country Status (1)

Country Link
CN (1) CN206295895U (en)

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Date Code Title Description
GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20180713

Address after: 611630 No. 51 Industrial South Road, Heshan Town, Pujiang, Chengdu, Sichuan

Patentee after: SICHUAN MOLCAN BIOLOGICAL PHARMACEUTICAL CO., LTD.

Address before: 610000 B7 8 8, Keyuan South Road, Chengdu hi tech Zone, Sichuan.

Patentee before: Chengdu Moer Biopharmaceutical Co., Ltd.

TR01 Transfer of patent right