CN206252562U - Pancreatic duct metal support - Google Patents

Pancreatic duct metal support Download PDF

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Publication number
CN206252562U
CN206252562U CN201620399874.3U CN201620399874U CN206252562U CN 206252562 U CN206252562 U CN 206252562U CN 201620399874 U CN201620399874 U CN 201620399874U CN 206252562 U CN206252562 U CN 206252562U
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CN
China
Prior art keywords
pancreatic duct
metal support
duct metal
support
ductus pancreaticus
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Expired - Fee Related
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CN201620399874.3U
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Chinese (zh)
Inventor
胡良皞
辛磊
李兆申
王丹
曾祥鹏
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Second Military Medical University SMMU
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Second Military Medical University SMMU
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Priority to CN201620399874.3U priority Critical patent/CN206252562U/en
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Abstract

The utility model is related to a kind of Pancreatic duct metal support for medically treating stricture of pancreatic duct, Pancreatic duct metal support includes the medication coat of latticed rack body, the polymeric material overlay film being coated on the rack body and the suppression epithelial growth being coated on the rack body that elastic metallic material is constituted, the Pancreatic duct metal support body includes bracket body part and the horn mouth holder part with diameter greater than bracket body part diameter, and the outer surface of the bracket body part of the Pancreatic duct metal support includes multiple bulge-structures.Using the Pancreatic duct metal support of this structure, epithelial tissue hyperplasia is not susceptible to, stricture of pancreatic duct can be well treated in a long time;And displacement is not susceptible in use, it is not easy to block the path of branch's ductus pancreaticus.

Description

Pancreatic duct metal support
Technical field
The utility model is related to technical field of medical instruments, is a kind of ductus pancreaticus for treating stricture of pancreatic duct specifically Metallic support.
Background technology
Stricture of pancreatic duct is the common lesion of pancreatic disease, and malignant stricture is common in cancer of pancreas, and benign stricture is common in chronic pancreas Adenositis.Good pernicious stricture of pancreatic duct can cause pancreatemphraxis, cause pancreatic juice drainage not smooth, and secondary ductus pancreaticus is expanded or false cyst, Cause or aggravate stomachache, indigestion symptom, or even induce pancreatitis acute attack repeatedly, to the serious shadow of Patients With Chronic Pancreatitis Quality of life is rung, are then significantly shortened life cycle to Pancreas cancer patients.The traditional treatment of stricture of pancreatic duct is based on surgical operation, but phase Close complication serious, and some patientss cannot tolerate operation;Therefore clinically generally put using stents of pancreatic duct under scope in recent years Enter art to treat stricture of pancreatic duct.
Mainly using plastic stent, plastic stent can temporarily solve pancreatic juice circulation not to pancreatic Duct Stenting under current scope Smooth symptom, but its pipe is thin, and the effect at expansion stricture of pancreatic duct is weaker, and after pulling out, ductus pancreaticus quickly can ISR.The plastics pancreas Pipe holder generally used the cycle for 3 months, more than 3 months after most of plastic stent obstruction can occur, it is necessary to take out repeatedly and Insert again, increase patient suffering and medical expense.And due in pancreas main pancreatic duct send many branch's ductus pancreaticus, it is columnar Plastic stent is possible to that branch's ductus pancreaticus can be blocked in drainage main pancreatic duct while pancreatic juice, so as to cause the expansion of branch ductus pancreaticus, pancreas Glandular substance of prostate fibrosis.
After the narrow ductus pancreaticus of Metal stent placement can self expandable to original diameter, lasting expansion is produced to narrow tube wall Power, holding bracket stable, it is to avoid place the frequent replacing after plastic stent.Compared with plastic stent, it is open more preferably, be difficult Block, the duration is long.But metallic support also has obvious shortcoming, metallic support easily causes ductus pancreaticus inner tissue hyperplasia, produces new Narrow and obstruction, clinical test proves, even if placing overlay film type metallic support in ductus pancreaticus, ductus pancreaticus still inevitably occurs Epithelial cell or tumor cell proliferation infiltration cause adhesion or even to block support, and cannot pull out support in the later stage;And metal The general cylindrical outward appearance of support, this kind of support especially the metallic support of outer overlay film, be susceptible to when in use in ductus pancreaticus Side or lateral displacement, it is impossible to reach expected action effect, if there is largely ductus pancreaticus medial displacement, support is moved fully into In ductus pancreaticus, then it is only capable of taking out support by surgical operation, increases the pain and medical expense of patient.
In sum, there is provided it is a kind of can be used to treating stricture of pancreatic duct, be not susceptible to epithelium or tumour cell adhesion and can In drainage branch ductus pancreaticus pancreatic juice, use time it is more long and be not susceptible to displacement Pancreatic duct metal support turn into this medical field Need badly.
Utility model content
The technical problem urgently to be resolved hurrily based on more than, the utility model provides a kind of Pancreatic duct metal support, including elasticity The latticed rack body of metal material composition, the polymeric material overlay film being coated on rack body, and it is coated in support sheet The medication coat of suppression ductus pancreaticus or tumor epithelia (hereinafter referred to as " epithelium ") growth on body.The overlay film of metallic stent body can be with Prevent epithelial cell from entering support pipeline and inducing blocking along the grid growth of metallic stent body.Suppress the medicine of epithelial growth Coating can effectively suppress Pancreatic duct metal support and hyperplasia and adhesion occur with the epithelial cell being in contact, and reduce support thin by hyperplasia The possibility that born of the same parents block, and contribute to support pull out operation.
Ductus pancreaticus metal provided by the utility model, when polymeric material overlay film is located at all interior table of Pancreatic duct metal support During face, medication coat is located at whole outer surfaces of the metallic stent body of Pancreatic duct metal support;When polymeric material overlay film is located at During whole outer surfaces of Pancreatic duct metal support, medication coat is located at two end regions of the metallic stent body of Pancreatic duct metal support Inner surface.When the inner surface overlay film of Pancreatic duct metal support, histocyte adhesion is susceptible on exposed metallic support, therefore The releasable all positions contacted with ductus pancreaticus inwall to support of medicine of the suppression epithelial growth of support whole outer surface are coated on, So as to further prevent to produce epithelial hyperplasia in ductus pancreaticus;When the outer surface overlay film of Pancreatic duct metal support, body cavity inner tissue Normally only there is the two-port neighbouring position of support in hyperplasia, it is therefore desirable in the petiolarea of rack body two of Pancreatic duct metal support The medication coat for suppressing epithelial growth is coated on the inner surface in domain.Medication coat ensure that the unimpeded of Pancreatic duct metal support pipeline, Extend the service life of Pancreatic duct metal support, reduce sufferer pain and medical treatment cost.
Pancreatic duct metal support provided by the utility model, medication coat is by molten in having resilient medicament sustained-release matrix Solution has the medicine for suppressing epithelial growth to constitute.Compared to metallic support directly with suppress epithelial growth medicine dipping, set up medicine Thing sustained-release matrix can as far as possible extend the duration of the medicine for suppressing epithelial growth, it is ensured that the good sustained release effect of medicine.Medicine Sustained-release matrix will have appropriate medicament slow release curve, and with certain elasticity, medicament sustained-release matrix can include phosphocholine, shell Polysaccharid derivative or inorganic matter.Suppress epithelial growth medicine include taxol, cyclosporin, rapamycin, rheum emodin, The combination of one or more medicines in Sai meter Song, mitomycin, D actinomycin D, bleomycin, adriamycin, so as to effectively suppress Fibroblastic mitosis and propagation, prevent the precipitation of collagen and fibronectin, reduce granulation tissue hyperplasia, prevent Tissue adhesion, is conducive to the extraction after support long-time indwelling.
To solve the problems, such as that stents of pancreatic duct is shifted, the rack body of Pancreatic duct metal support provided by the utility model includes Bracket body part and the horn mouth holder part with diameter greater than rack body diameter;Pancreatic duct metal support is being put into work Behind position, bracket main body portion is placed in ductus pancreaticus, in the duodenum that horn mouth holder part is placed in outside ductus pancreaticus mouthful.Using above-mentioned The Pancreatic duct metal support of structure, the dilatancy to ductus pancreaticus wall is good, can effectively treat the pancreas that chronic pancreatitis or cancer of pancreas cause Guan Liang/malignant stricture, and ductus pancreaticus mouthful Outboard Sections are adopted as the bell-mouth structure of air of diameter increase, can well prevent ductus pancreaticus There is the displacement on the inside of to ductus pancreaticus in validity period in support.
The exterior surface area of the bracket body part of Pancreatic duct metal support provided by the utility model is comprising multiple raised Structure.On the one hand the bulge-structure can increase the contact friction force of rack surface and ductus pancreaticus, effectively prevent stents of pancreatic duct to pancreas Pipe inner side and/or the displacement in outside;Another aspect bulge-structure makes to produce gap between ductus pancreaticus wall and rack body, can be with drainage Pancreatic juice in branch's ductus pancreaticus, it is to avoid the blocking of branch's ductus pancreaticus.
Preferably, the bulge-structure of anti-displacement is the bulge-structure being integrally formed with rack body when making rack body, That is, knit out or laser ablation goes out the rack body with bulge-structure when metallic stent body is made.Bulge-structure one Determine to be increased in degree the external diameter of support, extend narrow ductus pancreaticus, not only increase the friction between rack surface and ductus pancreaticus wall Power, prevents displacement of the stents of pancreatic duct during indwelling;And serve the effect of drainage branch ductus pancreaticus.
Preferably, when overlay film is located at metallic stent body outer surface, the bulge-structure of anti-displacement is in rack outer surface Covering material on formed, from covering material surface towards support horn mouth roll tiltedly extend polymeric material microtrabeculae Ridge;When overlay film is located at metallic stent body inner surface, the bulge-structure of anti-displacement is the metallic stent body in support Upper formation, grid from metallic stent body surface crosspoint rolls the polymeric material for tiltedly extending towards the horn mouth of support The microtrabeculae ridge of material.It is further preferred that microtrabeculae ridge can be cylinder or polyhedron prism, and its top surface is configured to With the diameter parallel of bracket body part.Microtrabeculae ridge is relative to form the support of " giving birth to " sample with ductus pancreaticus tube wall, not only extends Ductus pancreaticus tube wall, increases the frictional force between support and ductus pancreaticus tube wall, and produce what is shifted laterally to incline in Pancreatic duct metal support Xiang Shi, the microtrabeculae ridge of " giving birth to " structure is in close contact with ductus pancreaticus wall there is " locking " effect, considerably increase deboost To prevent support to ductus pancreaticus lateral displacement, be more effectively prevented from stents of pancreatic duct in use towards the shifting on the outside of ductus pancreaticus Position.Likewise, microtrabeculae ridge makes to form gap between the rack body of Pancreatic duct metal support and ductus pancreaticus wall, effectively play and drawn The effect of flow branching ductus pancreaticus.
It is surrounded with the periphery grid of the apex zone of the horn section of the Pancreatic duct metal support that the utility model is provided Exhausting line;One end of exhausting line is the fixing end being connected with the apex zone of horn mouth holder part, and the other end is indwelling in loudspeaker Free end outside mouth holder part.The opening of horn mouth holder part can be punctured into diameter very little after free end is tensed Dots structure, pulling on exhausting line easily can extract Pancreatic duct metal support from ductus pancreaticus, and the tubulose branch that opening closes Frame structure is transported and removed more easily in body cavity.
Pancreatic duct metal support provided by the utility model, bracket body part can be linearly extended columnar structured. Cylinder-shaped bracket main body is traditional stent configuration, and its is simple for production, and cost is relatively low, and good to the supportive of ductus pancreaticus wall.
Used as the further preferred structure of the utility model, the bracket body part of Pancreatic duct metal support can be multiple cydariforms Section it is end to end into linear structure.The cylinder-shaped bracket consistent compared to external diameter, big path smooth company interlaced with each other Connect cydariform section it is end to end into linear structure support be less susceptible in narrow ductus pancreaticus slide, prevent stents of pancreatic duct Displacement when in use.
Used as the further preferred structure of the utility model, the bracket body part of Pancreatic duct metal support can be spatially spiral shell It is columnar structured that rotation extends.The Pancreatic duct metal support in an unstressed state, can naturally keep helical configuration spatially; The Pancreatic duct metal support is compressed into straight configuration to be delivered near ductus pancreaticus in scope transmission system by narrow cavity, and by Constraint, the support in ductus pancreaticus wall are released into ductus pancreaticus with straight configuration;The support for being released into linear is reverted back to The inner principles of the helical configuration under unstress state, therefore expansion increase of the support to ductus pancreaticus wall, increase both significantly Between stiction so that stents of pancreatic duct is less susceptible to be shifted over when in use.
Brief description of the drawings
The utility model is described in more detail with reference to the accompanying drawings and detailed description:
The structure sectional view of the Pancreatic duct metal support that Fig. 1 is provided by embodiment of the present utility model 1;
The structure sectional view of the Pancreatic duct metal support that Fig. 2 embodiments 2 of the present utility model are provided;
The structure sectional view of the Pancreatic duct metal support that Fig. 3 embodiments 3 of the present utility model are provided;
The structure sectional view of the Pancreatic duct metal support that Fig. 4 embodiments 4 of the present utility model are provided;
The rack body front view of the Pancreatic duct metal support that Fig. 5 is provided by embodiment of the present utility model 5;
The rack body stereogram of the Pancreatic duct metal support that Fig. 6 is provided by embodiment of the present utility model 6.
The reference and part being related in accompanying drawing are as follows:
1st, 1 ', 1 〞-bracket body part
2- horn mouth holder parts
3- overlay films
The bulge-structure that 4- metallic stent bodies are formed
The microtrabeculae ridge of 4 '-polymeric material
5- exhausting lines
6- suppresses the medication coat of epithelial growth
Specific embodiment
Presently in connection with accompanying drawing, better embodiment of the present utility model is discussed in detail.Although description of the present utility model will Introduced together with reference to each implementation method, but this feature for not representing this utility model is only limitted to the several embodiments.Just Just conversely, with reference to the purpose that implementation method makees utility model introduction being had based on claim of the present utility model to cover Other selections or transformation that may extend.Depth of the present utility model is understood in order to provide, will be comprising perhaps in below describing Many concrete details.The utility model can not also use these details to implement.Additionally, in order to avoid chaotic or fuzzy this practicality New emphasis, some details will be omitted in the de-scription.
In addition, the "left", "right" for being used in the following description, " top ", " bottom " are to preferably describe this practicality New better embodiment and set, should not be construed as to limitation of the present utility model.
1. embodiment 1
Fig. 1 is the structure sectional view of the Pancreatic duct metal support that embodiment of the present utility model 1 is provided, wherein, overlay film position In the outer surface of Pancreatic duct metal support body.Rack body and be coated on that Pancreatic duct metal support is made comprising elastic metallic material The overlay film of rack body outer surface.The material of metallic stent body can be in the range of room temperature to human body temperature, with superlastic The marmem of property mechanical property, such as Ti-Ni alloy;The metal wire knitted that metallic stent body can be made up of above-mentioned material Form, or carved from bulk metal material using laser etching process and form.The material of overlay film is typically designed as polymer Material, including polyurethane, silicones etc., can effectively prevent the hyperplastic tissue in ductus pancreaticus from being given birth to by the mesh on metallic stent body Grow into rack bore and block support path.
In embodiment of the present utility model 1, the right part of Pancreatic duct metal support is that in ductus pancreaticus, biography is placed in when using The cylinder-shaped bracket main part 1 of system, relative to cylinder-shaped bracket main part 1, the left part of Pancreatic duct metal support is to make ID, the diameter that used time is placed in outside ductus pancreaticus mouthful significantly increase to prevent horn mouth branch of the support to ductus pancreaticus medial displacement Frame part 2;The outer surface of whole metallic stent body all have overlay film 3;Outside the apex zone of broadening formation holder part 2 Exhausting line is surrounded with all grids;One end of exhausting line 5 is the fixing end being connected with the apex zone of horn mouth holder part, separately One end is indwelling in the free end outside horn mouth holder part;When treatment end need to pull out Pancreatic duct metal support, only need to including The broadening formation holder part 2 of the free end of exhausting line 5, Pancreatic duct metal support is pulled just to bounce back a bit, to pull under mirror Support just can be pulled out and reclaimed by exhausting line 5.
As shown in figure 1, the point-like that the medication coat 6 for suppressing epithelial growth is arranged at the left and right two ends of Pancreatic duct metal support is cloudy Shadow zone domain, medication coat 6 is located at the inner surface of metallic stent body.Because the Pancreatic duct metal support in embodiment 1 is outer overlay film Support, will not typically produce cytoadherence on the overlay film of high molecular polymer, therefore only need to be in two end regions of stent inner surface The medication coat 6 that coating suppresses epithelial growth is that can reach the purpose for preventing hyperplasia from blocking support.The medication coat by The medicine for having dissolution inhibition epithelial growth in resilient medicament sustained-release matrix is constituted.Compared to metallic support directly with suppression on The medicine dipping of skin growth, setting up medicament sustained-release matrix can as far as possible extend the release time for suppressing epithelial growth medicine, it is ensured that medicine The good sustained release effect of thing.Medicament controlled-release coating will have appropriate medicament slow release curve, and with certain elasticity, can include phosphorus Sour choline coating, chitosan derivatives coating, inorganic coating.The medicine for suppressing epithelial growth includes taxol, cyclosporin, thunder One or more medicines in handkerchief mycin, rheum emodin, dexamethasone, mitomycin, D actinomycin D, bleomycin, adriamycin Combination, so as to effectively suppress fibroblastic mitosis and propagation, prevents the precipitation of collagen and fibronectin, reduces Granulation tissue hyperplasia, prevents tissue adhesion, is extracted after being easy to support long-time indwelling.Therefore, can be thin by modulating suppression epithelium The medicament slow release cycle of born of the same parents' hyperplasia controls the service life of Pancreatic duct metal support, typically can extend to 6 months.
Embodiment 1 as shown in Figure 1, is woven with or is carved with and branch on the cylinder-shaped bracket body 1 of Pancreatic duct metal support The integrally formed metal bump structure 4 of frame body, accordingly, is attached to this with raised cylinder-shaped bracket body outer surface Overlay film 3 also can therewith produce projection.Therefore, compared to the outer overlay film Pancreatic duct metal support without bulge-structure, this practicality is new The support that type embodiment 1 is provided increases the expansion to narrow ductus pancreaticus wall, and increasing prevents the friction of stent migration from hindering Power.In addition, main pancreatic duct separates many branch's ductus pancreaticus to supply pancreatic juice in pancreas, due to traditional cylindrical plastic stents of pancreatic duct outside Close contact at surface and stricture of pancreatic duct, plugs the path of many branch's ductus pancreaticus;In the utility model, bulge-structure 4 Setting, make to generate gap between Pancreatic duct metal support and ductus pancreaticus wall, so that for the unobstructed outflow of pancreatic juice in branch's ductus pancreaticus is opened Path is warded off.
2. embodiment 2
Fig. 2 is the sectional view of the Pancreatic duct metal support that embodiment of the present utility model 2 is provided, and wherein overlay film is located at ductus pancreaticus The outer surface of metallic stent body.It is similar to Example 1, the support sheet that the Pancreatic duct metal support is made comprising elastic metallic material Body and the overlay film for being coated on rack body outer surface;The right part of Pancreatic duct metal support is traditional cylinder-shaped bracket main part Point 1, relative to cylinder-shaped bracket main part 1, the horn mouth branch that the left part of Pancreatic duct metal support is significantly increased for diameter Frame part 2, can effectively prevent support medial displacement and slip into ductus pancreaticus;The outer surface of whole metallic stent body all have and cover Film 3;The top of broadening formation holder part 2 is provided with exhausting line 5, facilitates pulling out and reclaiming for support;Such as Fig. 2 medium-height trestles two ends Shown in neighbouring dot-hatched region, the medication coat 6 for suppressing epithelial growth is arranged at the petiolarea of left and right two of Pancreatic duct metal support The inner surface in domain;Same as Example 1, the setting of the overlay film 3 and medication coat 6 of rack outer surface can substantially reduce ductus pancreaticus metal , so as to extend the service life of Pancreatic duct metal support, therefore not to repeat here for the probability that support is blocked by epithelial proliferation cell.
According to embodiment 2, it is provided with the overlay film of the cylinder-shaped bracket main body of Pancreatic duct metal support from overlay film surface and is inclined The microtrabeculae ridge 4 ' of the polymeric material for upwardly extending.The position of microtrabeculae ridge 4 ' does not limit, and both can be located at metallic support sheet Network central area (such as the position of the microtrabeculae ridge 4 ' that dotted circle in Fig. 2 is illustrated) on body, may be alternatively located at gold On the crosspoint of the network for belonging to rack body (position as inclined the microtrabeculae ridge 4 ' anticipated shown in column in Fig. 2);It is micro- Post ridge 4 ' can use same polymeric material with overlay film, such as polyurethane, silicones, can both have been poured with overlay film and be integrally formed (as shown in Figure 2), can independently form independently of overlay film again.Preferably, the shape of microtrabeculae ridge 4 ' can be cylinder or multiaspect Body prism, and for center rest and the relative position of ductus pancreaticus wall, the top of microtrabeculae is arranged to the axle with cylinder-shaped bracket main body The parallel top surface of line.Compared to the cylinder-shaped bracket main body without bulge-structure, the microtrabeculae ridge 4 ' has more been expanded narrow Ductus pancreaticus, increases the critical stiction for being shifted over Pancreatic duct metal support, and " giving birth to " structure is in close contact with ductus pancreaticus wall And " locking " effect is produced, considerably increase the resistance that Pancreatic duct metal support is shifted laterally.Other, microtrabeculae ridge 4 makes Gap is generated between Pancreatic duct metal support and ductus pancreaticus wall, is that the outflow of pancreatic juice in branch's ductus pancreaticus opens path, thus played The effect of drainage branch ductus pancreaticus.
3. embodiment 3
Fig. 3 be the utility model embodiment 3 provide Pancreatic duct metal support profile, wherein overlay film be located at ductus pancreaticus The inner surface of metallic stent body.The right part of Pancreatic duct metal support is traditional cylinder-shaped bracket main part 1, left side It is divided into the horn mouth holder part 2 that diameter is significantly increased, is fallen into ductus pancreaticus with preventing support medial displacement;Whole metallic support The inner surface of body all have overlay film 3;The top of broadening formation branch part 2 is provided with exhausting line 5, facilitate support pull out and Reclaim;As shown in figure 3, the medication coat 6 for suppressing epithelial cell growth is coated on whole outer surfaces of Pancreatic duct metal support body, Medicament slow release can be entered in longer time in the contact area of ductus pancreaticus and support, so as to ensure Pancreatic duct metal support in medicine The sustained release cycle in not with ductus pancreaticus parietal cell produce adhesion.
According to embodiment 3, the projection of the cylinder-shaped bracket body portion outer surface of Pancreatic duct metal support is metal material shape Into bulge-structure 4, braiding style when bulge-structure 4 can be braided metal rack body is raised, or laser ablation gold The raised style carved out during category rack body.Compared to the interior precoated metal support on smooth cylindrical surface, bulge-structure 4 both increased Big frictional force of the Pancreatic duct metal support with ductus pancreaticus inwall, so as to effectively prevent the displacement that may occur during use;Again The effect of outflow pancreatic juice in drainage branch ductus pancreaticus is served, the expansion of branch ductus pancreaticus, pancreas are caused so as to prevent branch's ductus pancreaticus from blocking Glandular substance of prostate fibrosis.
4. embodiment 4
Fig. 4 is the profile of the Pancreatic duct metal support that embodiment of the present utility model 4 is provided, and wherein overlay film is located at ductus pancreaticus The inner surface of metallic stent body.The right part of the Pancreatic duct metal support is traditional cylinder-shaped bracket main part 1, left side The horn mouth holder part 2 that part significantly increases for diameter, to prevent support to ductus pancreaticus medial displacement;Whole metallic stent body Inner surface all have overlay film 3;The top of horn mouth holder part 2 is provided with exhausting line 5, facilitates pulling out and returning for support Receive;As shown in figure 4, the medication coat 6 for suppressing epithelial cell growth is coated on whole outer surfaces of Pancreatic duct metal support body, can Medicament slow release is entered in longer time in the contact area of ductus pancreaticus and support, so as to ensure Pancreatic duct metal support in medicine Adhesion is not produced in the sustained release cycle with epithelial cell.According to embodiment 4, as inclined column and dashed circle institute ductus pancreaticus gold in Fig. 4 Belong to the bulge-structure set in the cylinder-shaped bracket main part of support be formed on the metallic stent body of support, from gold The microtrabeculae of the polymeric material that the horn mouth holder part of the crosspoint inclined support of the grid on category rack body surface extends Ridge 4 '.The microtrabeculae ridge 4 ' can use same polymeric material, such as polyurethane, silicones with overlay film, it is preferable that micro- The shape of post ridge 4 ' can be cylinder or polyhedron prism, and for center rest and the relative position of ductus pancreaticus wall, microtrabeculae Top surface set and the diameter parallel of cylinder-shaped bracket main body.The microtrabeculae ridge 4 ' for being somebody's turn to do " giving birth to " structure closely connects with ductus pancreaticus wall Touch and produce " locking " effect, considerably increase the resistance that Pancreatic duct metal support is shifted laterally;Likewise, the microtrabeculae ridge 4 ' the effects for serving the pancreatic juice of outflow in drainage branch ductus pancreaticus.
5. embodiment 5
The front view of the rack body of the Pancreatic duct metal support that Fig. 5 is provided by embodiment of the present utility model 5.In order to increase The critical friction power that expansion and increase of the big bracket body part to narrow ductus pancreaticus make rack body be shifted in ductus pancreaticus, such as Shown in Fig. 5, the bracket body part of Pancreatic duct metal support body can be arranged to cydariform section it is end to end into linear structure 1 ˊ.Similar to embodiment 1-4, the overlay film of the Pancreatic duct metal support described by embodiment 5 may be disposed at whole appearances of rack body Face or whole inner surface, accordingly, suppress epithelial cell growth medication coat may be disposed at rack body two end regions it is attached Whole outer surfaces of near or rack body;And rising for setting prevents stent migration and drainage point on cydariform section bracket body part 1 ˊ The bulge-structure of branch ductus pancreaticus effect can be the bulge-structure 4 of the metal material being integrally formed with metallic stent body, or correspondingly It is the microtrabeculae ridge of the polymeric material of " giving birth to " formed on overlay film or on the crosspoint of metallic stent body surface mesh 4′.Though the various concrete structures of above-mentioned support show not in the drawings, those skilled in the art can be from embodiment 1 to 4 Any of the above structure exactly, is unambiguously determined in description, therefore be will not be described here.
6. embodiment 6
The schematic perspective view of the rack body of the Pancreatic duct metal support that Fig. 6 is provided by embodiment of the present utility model 6.For Increase bracket body part is to the expansion of narrow ductus pancreaticus and increases the critical friction for making rack body be shifted in ductus pancreaticus Power, as shown in fig. 6, traditional linearly extended cylindrical-shaped main body part of Pancreatic duct metal support body can be replaced by space On the 〞 of cylinder-like structure 1 that extends spirally, and under stressless nature, the rack body of the Pancreatic duct metal support can be protected Hold the form of spatially spiral.When using, the support is compressed to straight configuration to be sent to ductus pancreaticus mouthful in scope transmission system Near, and under the constraint effect of narrow ductus pancreaticus wall, discharged to ductus pancreaticus by the configuration near linear;Support tool after release There are the spiral elastic-restoring force of recovery, pressure and stiction of the increase to ductus pancreaticus wall.It is similar to embodiment 1-4, embodiment 6 The overlay film of described Pancreatic duct metal support may be disposed at whole outer surfaces of rack body or whole inner surfaces, accordingly, suppression The medication coat of epithelial cell growth processed may be disposed at the two ends areas adjacent of rack body or whole outer surfaces of rack body; And serving of being set on bracket body part prevents the bulge-structure of stent migration and drainage branch ductus pancreaticus from can be and metal branch The bulge-structure 4 of the integrally formed metal material of frame body, or be correspondingly on overlay film or metallic stent body surface mesh The microtrabeculae ridge 4 ' of the polymeric material of " giving birth to " for being formed on crosspoint.Though the various concrete structures of above-mentioned support are not attached In figure show, but those skilled in the art can from the description of embodiment 1 to 4 exactly, unambiguously determine more than respectively Structure is planted, therefore be will not be described here.
Better embodiment of the present utility model is illustrated above, but the utility model not limited to this, do not taking off In the range of its objective, can various modifications be carried out to implement.
Shape such as the horn section of the Pancreatic duct metal support body of the utility model offer is not limited in this specification Structure shown in the drawings, as long as diameter significantly increased relative to bracket body part, can play prevent support to ductus pancreaticus inner side The structure of a mobile, position-limiting action is in protection domain of the present utility model.
And for example the horn section outer surface of Pancreatic duct metal support may also set up above-mentioned various bulge-structure types, such as gold The microtrabeculae ridge of the polymeric material of category material bulge-structure or " giving birth to ".
And for example the microtrabeculae ridge of the polymeric material of Pancreatic duct metal support outer surface can be unified shape, or not The combination of same shape (cylinder and polyhedron prism).
And for example Pancreatic duct metal support appearance metallic stent body formed bulge-structure can be annular, intersect annular with Form latticed, or other can arbitrarily form the shape of bulge-structure.

Claims (13)

1. a kind of Pancreatic duct metal support, it is characterised in that:
The Pancreatic duct metal support includes the latticed rack body of elastic metallic material composition, is coated on the rack body Polymeric material overlay film and be coated on the rack body suppression epithelial growth medication coat,
When the polymeric material overlay film is located at whole inner surfaces of the Pancreatic duct metal support body, the medication coat position In whole outer surfaces of the rack body of the Pancreatic duct metal support;
When the polymeric material overlay film is located at whole outer surfaces of the Pancreatic duct metal support body, the medication coat position In the inner surface of two end regions of the rack body of the Pancreatic duct metal support.
2. Pancreatic duct metal support as claimed in claim 1, it is characterised in that the medication coat is by having resilient medicine The medicine composition for suppressing epithelial growth is dissolved with sustained-release matrix.
3. Pancreatic duct metal support as claimed in claim 2, it is characterised in that the sustained-release matrix includes that phosphocholine, shell gather Sugar derivatives or inorganic matter.
4. Pancreatic duct metal support as claimed in claim 2, it is characterised in that the medicine of the suppression epithelial growth includes Japanese yew In alcohol, cyclosporin, rapamycin, rheum emodin, dexamethasone, mitomycin, D actinomycin D, bleomycin, adriamycin one The combination of kind or several drugses.
5. Pancreatic duct metal support as claimed in claim 1, it is characterised in that the Pancreatic duct metal support body includes support master Body portion and the horn mouth holder part with diameter greater than the bracket body part diameter;
After the Pancreatic duct metal support is put into operating position, the bracket main body portion is placed in ductus pancreaticus, the loudspeaker In the duodenum that mouth holder part is placed in outside ductus pancreaticus mouthful.
6. Pancreatic duct metal support as claimed in claim 5, it is characterised in that the bracket body part of the Pancreatic duct metal support Exterior surface area include multiple bulge-structures.
7. Pancreatic duct metal support as claimed in claim 6, it is characterised in that the bulge-structure for make during rack body with The integrally formed bulge-structure of rack body.
8. Pancreatic duct metal support as claimed in claim 6, it is characterised in that
When the overlay film is located at the Pancreatic duct metal support body outer surface, the bulge-structure is in the rack outer surface Covering material on formed, from covering material surface towards the horn mouth holder part of the support roll tiltedly extend polymer The microtrabeculae ridge of material;
When the overlay film is located at metallic stent body inner surface, the bulge-structure is the metallic stent body in the support Horn mouth holder part on upper formation, grid from metallic stent body surface crosspoint towards the support is rolled and tiltedly prolonged The microtrabeculae ridge of the polymeric material stretched.
9. Pancreatic duct metal support as claimed in claim 8, it is characterised in that the microtrabeculae ridge can be cylinder or multiaspect Body prism, and the microtrabeculae ridge the top surface diameter parallel that is configured to the bracket body part.
10. the Pancreatic duct metal support as described in claim 5 or 7 or 8, it is characterised in that the top of the horn mouth holder part Exhausting line is surrounded with the periphery grid of end regions;One end of the exhausting line is the top zone with the horn mouth holder part The fixing end of domain connection, the other end is indwelling in the free end outside horn mouth holder part.
11. Pancreatic duct metal supports as claimed in claim 5, it is characterised in that the bracket main body portion is divided into linearly extended It is columnar structured.
12. Pancreatic duct metal supports as claimed in claim 5, it is characterised in that the bracket main body portion is divided into multiple cydariform sections The structure of the end to end shape that is in line.
13. Pancreatic duct metal supports as claimed in claim 5, it is characterised in that the bracket main body portion is divided into spatially spiral What is extended is columnar structured.
CN201620399874.3U 2016-05-05 2016-05-05 Pancreatic duct metal support Expired - Fee Related CN206252562U (en)

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Application Number Priority Date Filing Date Title
CN201620399874.3U CN206252562U (en) 2016-05-05 2016-05-05 Pancreatic duct metal support

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CN206252562U true CN206252562U (en) 2017-06-16

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108272487A (en) * 2018-02-11 2018-07-13 南京普微森医疗科技有限公司 A kind of braided support system

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108272487A (en) * 2018-02-11 2018-07-13 南京普微森医疗科技有限公司 A kind of braided support system
CN108272487B (en) * 2018-02-11 2023-12-29 南京普微森医疗科技有限公司 Braided support system

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