CN205994771U - A kind of skin reparative membrane - Google Patents

A kind of skin reparative membrane Download PDF

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Publication number
CN205994771U
CN205994771U CN201620198141.3U CN201620198141U CN205994771U CN 205994771 U CN205994771 U CN 205994771U CN 201620198141 U CN201620198141 U CN 201620198141U CN 205994771 U CN205994771 U CN 205994771U
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China
Prior art keywords
membrane
skin
bacteria cellulose
cellulose film
woven
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CN201620198141.3U
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Chinese (zh)
Inventor
马百聚
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Yantai Zhenghai Bio-Tech Co Ltd
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Yantai Zhenghai Bio-Tech Co Ltd
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Abstract

The utility model discloses a kind of skin reparative membrane;Belong to medical composite material technical field;Technical points include connecting hole, dense form bacteria cellulose film, microsphere, loose type bacteria cellulose film, polyurethane non-woven membrane, micropore semi-permeable membrane, biomacromolecule thin film, and the lower section of described biomacromolecule thin film is provided with the micropore semi-permeable membrane being made up of Polyethylene Glycol;The lower surface of described micropore semi-permeable membrane is provided with some connecting holes caving inward;Described polyurethane non-woven membrane is bonded in the surface of dense form bacteria cellulose film by medical alite paste;The surface of described dense form bacteria cellulose film is provided with some prominent microspheres;Described dense form cellulose membrane is closely connected with loose type bacteria cellulose film by the molecular layer that intramolecular in Fructus Vitis viniferae sugar chain is combined to form with intermolecular hydrogen bonding;This utility model aims to provide a kind of skin reparative membrane with epidermal area and skin corium;Repair for different degrees of skin injury.

Description

A kind of skin reparative membrane
Technical field
This utility model is related to a kind of medical composite material technical field, and more specifically, more particularly, to a kind of skin is repaiied Laminating adhesive.
Background technology
Skin refers to tissue outside muscle for the body surface bag, is the maximum organ of human body, mainly carries protection body Body, perspire, feel cold and hot and pressure effect.Skin cover whole body, it can make in vivo various histoorgans from physical property, machine The invasion and attack of tool, chemical and pathogenic microbes.Therefore when skin is subject to wound, burn, inflammation etc. to damage, especially when big When the skin of area is severely damaged, wound should be protected immediately.
For the reparation of damaged skin, mostly use before and adopt auto-skin grafting, doctor is from patient's body The intact skin of next block is removed at other positions of body, again implants wound site, but this method not only causes skin donor site new Wound, but also limited by originating for skin, additionally, the skin of the transplanting skin neighbouring with wound site exist color and luster, Quality and difference functionally.Some doctors carried out skin repair using the method cultivating corium confluent monolayer cells later, but due to There is no complete skin histology, the skin newly growing always has many defects.Now it is badly in need of one kind and have epidermal area and true simultaneously The artificial skin repair membrane of cortical tissue, directly adopts artificial skin to accelerate the reparation of damaged skin.
Utility model content
The purpose of this utility model is for above-mentioned the deficiencies in the prior art, provides one kind to have artificial epidermal area simultaneously With the skin reparative membrane of artificial dermis layer, directly adopt the reparation accelerating to damaged skin close to organization of human body artificial skin.
The technical solution of the utility model is realized in:A kind of skin reparative membrane, including connecting hole, dense form antibacterial Cellulose membrane, microsphere, loose type bacteria cellulose film, non-woven membrane, micropore semi-permeable membrane, biomacromolecule thin film, described The lower section of biomacromolecule thin film is provided with the micropore semi-permeable membrane being made up of Polyethylene Glycol;Under described micropore semi-permeable membrane Surface is provided with some connecting holes caving inward;One end of described polyurethane non-woven membrane is connected with micropore semi-permeable membrane, separately One end is bonded in the surface of dense form bacteria cellulose film by medical alite paste;The surface of described dense form bacteria cellulose film It is provided with some prominent microspheres;Described dense form cellulose membrane is combined to form with intermolecular hydrogen bonding by intramolecular in Fructus Vitis viniferae sugar chain Molecular layer be closely connected with loose type bacteria cellulose film;Bacterial cellulose in described dense form bacteria cellulose film is in vertical To arrangement, the Bacterial cellulose in described loose type bacteria cellulose film is in disorderly arranged.
Further, described dense form bacteria cellulose film and loose type bacteria cellulose film are closely joined together composition Skin corium in skin reparative membrane, the thickness of described loose type bacteria cellulose film is 5mm.
Further, described dense form bacteria cellulose film and loose type bacteria cellulose film are to consume sugar source by strain, Eccrine fiber element fibril by Intramolecular between hydrogen bonded form;Described strain is refer to biosynthesiss cellulose micro- Biological.
Further, described biomacromolecule thin film is built-up by fibroin albumen and shitosan, described biological big Molecular film and micropore semi-permeable membrane constitute the epidermal area in skin reparative membrane.
Further, described non-woven membrane is polyurethane non-woven membrane.
Further, the thickness of described polyurethane non-woven membrane is 1.5mm, and described polyurethane non-woven membrane is in skin repair After the completion of can Automatic-falling, will not stick together with skin, it is to avoid second hurt.
Further, described dense form bacteria cellulose film and loose type bacteria cellulose film need first to soak before use Bubble, in the pure water being placed in high-pressure sterilizing pot, carries out 121 DEG C of sterilization treatment, takes out and be cooled to room temperature, finally 4 after 30 minutes Preserved in the case of DEG C.
After this utility model adopts said structure, 1. do not need using autologous skin-grafting, it is to avoid cause new wound;2. make With there is the artificial skin of epidermal area and skin corium so that the new skin repaired is higher with the compatible degree of original skin simultaneously;3. Artificial skin is done using the bacteria cellulose material that density combines, enhances the breathability of skin, there is higher economic benefit Be widely applied prospect.
Brief description
The utility model is described in further detail for embodiment in below in conjunction with the accompanying drawings, but does not constitute to this reality With new any restriction.
Fig. 1 is structural representation of the present utility model.
Fig. 2 is side view of the present utility model.
In Fig. 1:1- connecting hole, 2- dense form bacteria cellulose film, 3- microsphere, 4- loose type bacteria cellulose film, 5- are no Spin cloth film, 6- micropore semi-permeable membrane, 7- biomacromolecule thin film.
Specific embodiment
Below in conjunction with the accompanying drawing in this utility model embodiment, the technical scheme in this utility model embodiment is carried out Clearly and completely description is it is clear that described embodiment is only a part of embodiment of this utility model rather than whole Embodiment.Based on the embodiment in this utility model, those of ordinary skill in the art are not under the premise of making creative work The every other embodiment being obtained, broadly falls into the scope of this utility model protection.
Refering to shown in Fig. 1 and Fig. 2, this utility model provides a kind of technical scheme:A kind of skin reparative membrane, including connecting hole 1st, dense form bacteria cellulose film 2, microsphere 3, loose type bacteria cellulose film 4, non-woven membrane 5, micropore semi-permeable membrane 6, life Thing macromole thin film 7, in this utility model, described non-woven membrane 5 is polyurethane non-woven membrane, described biomacromolecule thin film 7 lower section is provided with the micropore semi-permeable membrane 6 being made up of Polyethylene Glycol;If the lower surface of described micropore semi-permeable membrane 6 is provided with The dry connecting hole 1 caving inward;One end of described non-woven membrane 5 is connected with micropore semi-permeable membrane 6, and the other end passes through medical viscous Patch is bonded in the surface of dense form bacteria cellulose film 2;The surface of described dense form bacteria cellulose film 2 is provided with some prominent Microsphere 3;The molecular layer that described dense form cellulose membrane 2 is combined to form with intermolecular hydrogen bonding by intramolecular in Fructus Vitis viniferae sugar chain with Loose type bacteria cellulose film 4 closely connects;Bacterial cellulose in described dense form bacteria cellulose film 2 is in longitudinal arrangement, Bacterial cellulose in described loose type bacteria cellulose film 4 is in disorderly arranged;Described dense form bacteria cellulose film 2 and loose Type bacteria cellulose film 4 is closely joined together the skin corium constituting in skin reparative membrane, described loose type Bacterial cellulose The thickness of film 4 is 5mm;Described dense form bacteria cellulose film 2 and loose type bacteria cellulose film 4 are to consume sugar source by strain, Eccrine fiber element fibril by Intramolecular between hydrogen bonded form;Described strain is refer to biosynthesiss cellulose micro- Biological;Described biomacromolecule thin film 7 is built-up by fibroin albumen and shitosan, described biomacromolecule thin film 7 He Micropore semi-permeable membrane 6 constitutes the epidermal area in skin reparative membrane;The thickness of described non-woven membrane 5 is 1.5mm, described nonwoven Cloth film 5 after the completion of skin repair can Automatic-falling, will not stick together with skin, it is to avoid second hurt;Described densification Type bacteria cellulose film 2 and loose type bacteria cellulose film 4 need before use to be first immersed in and are placed in the pure of high-pressure sterilizing pot In water, carry out 121 DEG C of sterilization treatment, take out after 30 minutes and be cooled to room temperature, finally preserved in the case of 4 DEG C.
Specific embodiments:First dense form bacteria cellulose film 2 and loose type bacteria cellulose film 4 are immersed in using front It is positioned in the pure water in high-pressure sterilizing pot, carries out 121 DEG C of sterilization treatment, take out after 30 minutes and be cooled to room temperature, finally 4 Preserved in the case of DEG C, during use, epidermal area and skin corium are pressed together and cultivated, dense form Bacterial cellulose Microsphere 3 on film 2 can be trapped in the connecting hole 1 on micropore semi-permeable membrane 6, uses alcohol swab at the impaired skin of patient Sign sterilization, subsequently artificial skin is applied the site of injury in patient, wrap wound, Bacterial cellulose mushrooms out in injury, protect Hold the wettability of compromised skin, moistening environment is easy to tissue regeneration, can also effectively mitigate the pain of patient, and special receives Rice structure promotes the interaction of cell, promotion organization regeneration and reduces scar tissue generation;Meanwhile, also help material in wound Conveniently, safely discharge the medicine of load at mouthful, promote wound healing further, bacterial cellulose skin regeneration material being capable of root Practical situation culture according to conditions of patients obtains the biological structure of upper tightly lower sparse similar to patient wound's skin, can be in very great Cheng The cycle of patient wound's healing is shortened on degree, and significantly reduces the generation of cicatrix after healing;Damaged skin repair difference not When many, polyurethane non-woven membrane 5 meeting Automatic-falling, adhesion will not be carried out with skin.
Embodiment provided above is better embodiment of the present utility model, is only used for convenient explanation this utility model, and Non- this utility model is made with any pro forma restriction, any those of ordinary skill in the art, if without departing from In the range of the carried technical characteristic of this utility model, using locally changing done by this utility model disclosed technology content or repair The Equivalent embodiments of decorations, and without departing from technical characteristic content of the present utility model, all still fall within this utility model technical characteristic In the range of.

Claims (5)

1. a kind of skin reparative membrane, including non-woven membrane, be located at non-woven membrane upper surface epidermal area and be located at non-woven membrane table The skin corium in face, described epidermal area and described skin corium respectively be located at described non-woven membrane both sides it is characterised in that:Described table Cortex is made up of biomacromolecule thin film and micropore semi-permeable membrane, and described skin corium is by loose type bacteria cellulose film and densification Type bacteria cellulose film forms, and described micropore semi-permeable membrane is connected with described non-woven membrane, described dense form Bacterial cellulose Film is by medical alite paste and described non-woven membrane adhesion;Described micropore semi-permeable membrane is provided with the company that several cave inward Connect hole;It is outwardly micro- that the one side of described sponginess bacteria cellulose film and described non-woven membrane adhesion is provided with several Ball.
2. a kind of skin reparative membrane according to claim 1 it is characterised in that:Described micropore semi-permeable membrane is by poly- second two Alcohol is made.
3. a kind of skin reparative membrane according to claim 2 it is characterised in that:Described dense form bacteria cellulose film and institute State loose type bacteria cellulose film and be contained within Bacterial cellulose, the Bacterial cellulose in described dense form bacteria cellulose film is in vertical To arrangement, the Bacterial cellulose in described loose type bacteria cellulose film is in disorderly arranged.
4. a kind of skin reparative membrane according to claim 1 it is characterised in that:Described non-woven membrane is polyurethane non-woven fabrics Film.
5. a kind of skin reparative membrane according to claim 4 it is characterised in that:The thickness of described polyurethane non-woven membrane is 1.5mm, the thickness of described loose type bacteria cellulose film is 5mm.
CN201620198141.3U 2016-03-15 2016-03-15 A kind of skin reparative membrane Active CN205994771U (en)

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Application Number Priority Date Filing Date Title
CN201620198141.3U CN205994771U (en) 2016-03-15 2016-03-15 A kind of skin reparative membrane

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CN205994771U true CN205994771U (en) 2017-03-08

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116036368A (en) * 2023-02-08 2023-05-02 苏州汇涵医用科技发展有限公司 Simple and efficient bacterial cellulose artificial skin and manufacturing process thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116036368A (en) * 2023-02-08 2023-05-02 苏州汇涵医用科技发展有限公司 Simple and efficient bacterial cellulose artificial skin and manufacturing process thereof

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CP02 Change in the address of a patent holder
CP02 Change in the address of a patent holder

Address after: 264006 No.7 Nanjing Street, Yantai Economic and Technological Development Zone, Shandong Province

Patentee after: YANTAI ZHENGHAI BIO-TECH Co.,Ltd.

Address before: 264000 Hengshan Road economic and Technological Development Zone, Shandong, No. 10,

Patentee before: YANTAI ZHENGHAI BIO-TECH Co.,Ltd.