CN205991901U - A kind of urine analysis system - Google Patents
A kind of urine analysis system Download PDFInfo
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- CN205991901U CN205991901U CN201620541178.1U CN201620541178U CN205991901U CN 205991901 U CN205991901 U CN 205991901U CN 201620541178 U CN201620541178 U CN 201620541178U CN 205991901 U CN205991901 U CN 205991901U
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Abstract
This case is a kind of urine analysis system, including：Urine Analyzer and micro-fluidic chip, wherein, described micro-fluidic chip is provided with several urinalysiss indicator paper blocks, and the fluid passage that communicate corresponding with urinalysiss indicator paper block each described；Flow into end with liquid, it connects to described fluid passage one end；Liquid outlet, it connects to the described fluid passage other end；Described Urine Analyzer includes the detection probe for detecting described urinalysiss indicator paper block, for connecting the connector of described micro-fluidic chip；And suction means, it connects described liquid outlet.The artificial operation part of this case is only and micro-fluidic chip is installed in urine analysis system, not only avoid and manually dips the time uncertainty that sample brings, also makes the relatively sanitary safety of whole operation process.
Description
Technical field
This utility model is related to medical instruments field and microfluidic control field, more particularly to a kind of urine analysis system.
Background technology
Urinalysiss are the important measuring means in Clinical Laboratory, and urine analysis system is usually used in hospital and each therapeutic machine
Structure.The fundamental mode of urine analysis system is：Using indicator paper block and in urine composition there is showing of chemical reaction and variable color
As being irradiated to the indicator paper block of immersion urine using light, and detecting color and the strength information of its reflected light, thus calculating
Go out the concentration of the chemical composition in urine.
Carry out urinalysiss using urine analysis system, need to use urinalysiss test strips.Common urinalysiss examination
Paper slip is made into strip, and its side carries the indicator paper block of multiple rectangles, and each indicator paper block corresponds to a detection project.Examination
Based on paper block is by the material (filter paper) easily absorbing water, particular agent is added to be made.Indicator paper block easily absorbs water, and works as test strips
After immersion urine, indicator paper block sucks urine, and the chemical composition in urine can occur chemistry with the reagent that is previously added in indicator paper block
Reaction, so that there is variable color in indicator paper block.
Because reagent paper color change is caused by chemical reaction, and part chemical reaction is when especially enzymatic reaction needs
Between, the therefore response time is directly related with color.Urine analysis system has strict setting generally for the response time of test strips
Fixed, the response time is long or too short all to make test result inaccurate.Using the urine analysis system of test strips, it is generally divided into half
Automatically with full-automatic two kinds.Full automatic urine analysis system, due to sampling and reagent paper reaction, reagent paper transport and reading color step
Rapid all automatizatioies carry out the concordance it is ensured that the response time.But for automanual urine analysis system, need people
Work participates in test process, completes the step that urine is immersed test strips, then test strips are put into the test strips of semi-automatic urine instrument
Ingoing silver region, will transport test strips and reads the work of color and give instrument in follow-up special time.Under normal circumstances, grasp
Make personnel by after test strips immersion urine, with an absorbent paper or other water absorber, test strips can be cleared up, with
Remove the unnecessary urine between the test strips back side, side and indicator paper block.Such operation, for people, cannot determine one completely
The individual exact operations time that all test strips are all suitable for.Thus bringing as a result, for automanual urinalysiss
System, the response time of reagent paper not can determine that, the accuracy of test result nor be guaranteed.Further, since urinalysiss
The optical system of system typically reads indicator paper block color from indicator paper block front, and urine also immerses indicator paper block from indicator paper block front,
The operation of urine has very big uncertainty, may make part indicator paper block remained on surface urine drop, changes indicator paper block surface
Light-reflecting property, thus affect color reading device read indicator paper block color accuracy.
Utility model content
For overcoming the deficiencies in the prior art, the purpose of this utility model is to provide one kind to use chip automatic sucking urine
Mode infiltrate indicator paper block, the urine analysis system that structure is simple, precision is higher.
For achieving the above object, this utility model is achieved through the following technical solutions：
A kind of urine analysis system, including：Including Urine Analyzer 10 and micro-fluidic chip 1, wherein,
Described micro-fluidic chip is provided with several urinalysiss indicator paper blocks 2, and with urinalysiss reagent paper each described
The fluid passage 3 that block correspondence communicates；With
Liquid flows into end 5, and connects to described fluid passage one end；
Liquid outlet 4, and connect to the described fluid passage other end；
Described Urine Analyzer includes the detection probe 8 for detecting described urinalysiss indicator paper block, described for connecting
The connector 6 of micro-fluidic chip；And
Suction means 7, it connects described liquid outlet.
Preferably, described urine analysis system, wherein, described Urine Analyzer also includes one and is used for unloading miniflow
The discharge mechanism 9 of control chip.
Preferably, described urine analysis system, wherein, the detection project of described urine analysis system includes but does not limit
In urobilinogen, bilirubin, ketoboidies, nitrite, erythrocyte, leukocyte esterase, proportion, pH value, protein, micro- albumin, Portugal
Grape sugar, ascorbic acid, creatinine, calcium, urine one of color and more than one.
Preferably, described urine analysis system, wherein, there is N bar described fluid passage, and leads in described N bar fluid
It is disposed with N number of urinalysiss indicator paper block, each described urinalysiss indicator paper block corresponds to a described fluid passage, described N in road
Be not less than 1 and no more than 15 integer；And described urinalysiss indicator paper block be can with described fluid passage in flow through to be checked
The urine specimen surveyed reacts and changes color.
Preferably, described urine analysis system, wherein, two larger sides of described urinalysiss indicator paper block area
, wherein there are the packing forms adopting printing opacity at least one side in face.Preferably, described urine analysis system, wherein, institute
State two larger sides of urinalysiss indicator paper block area, wherein have at least one side using exposing aerial encapsulation
Form.Preferably, described urine analysis system, wherein, described micro-fluidic chip is oblong-shaped, and described fluid passage
Parallel is distributed on described micro-fluidic chip.Preferably, described urine analysis system, wherein, described micro-fluidic chip
For disc-shape, and described fluid passage is radial is distributed on described micro-fluidic chip.Preferably, described urine
Analysis system, wherein, described micro-fluidic chip is cylindrical shape, and described urinalysiss indicator paper block is distributed in the side of described cylinder
Face.Preferably, described urine analysis system, wherein, described micro-fluidic chip is truncated conical shape, and the examination of described urinalysiss
Paper block is distributed in the side of described round platform.Preferably, described urine analysis system, wherein, described Urine Analyzer also wraps
Include a discharge mechanism for unloading micro-fluidic chip.Preferably, described urine analysis system, wherein, described detection
Located at the side of described micro-fluidic chip, it includes a moveable detection sensor to device.Preferably, described urine
Analysis system, wherein, described detection means includes N number of detection sensor, and that is, described detection sensor quantity and described urine are divided
Analysis reagent paper number of blocks is identical.
Preferably, described urine analysis system, wherein, described detection means includes a detection sensor and one
Drive the machinery of described micro-fluidic chip motion；Described detection sensor is used for gathering the face of described urinalysiss indicator paper block
Chromatic number evidence.
Preferably, described urine analysis system, wherein, described Urine Analyzer also include top and sidepiece shell,
Bottom enclosure, its top is additionally provided with display screen, sampling button and unloading button, wherein, is connected with suction below described sampling button
Take device；It is also associated with described discharge mechanism below described unloading button；Described suction means is cylindrical structural, described unloading
Device is nested in the outside of described suction means；Described suction means is connected with described connector by its internal pipeline.
Preferably, described urine analysis system, wherein, described detection means is located at the side of described micro-fluidic chip
Face, described detection means also includes：Main circuit board is fixed on framework side, and the linear electric motors with leading screw and two sliding guides are put down
That goes is arranged in lower portion, and walking circuit plate is connected across two interactive guide rods and with the linear electric motors with leading screw, described
Detection sensor is arranged on walking circuit plate, and walking circuit plate is connected to main circuit board by flexible winding displacement.
Preferably, described urine analysis system, wherein, described Urine Analyzer is in hand-held pipettor shape, including
Top casing, bottom enclosure, the side of described top casing is integrated with main electric component, this main electric component include circuit board,
Button and display screen, battery and wireless link block；The top of described Urine Analyzer is additionally provided with and connects adopting of suction means
Sample button, and connect the unloading button of described discharge mechanism；What this discharge mechanism was concentric is set in the outer of described suction means
Portion；The bottom of described suction means is connected with micro-fluidic chip as connector.
Preferably, described urine analysis system, wherein, described detection means includes the detection containing one piece of sensor
Sensor, for the motor driving described micro-fluidic chip to rotate, travelling gear, also includes one and is used for making described micro-fluidic core
Piece rotates motion, makes described indicator paper block move to the rotating mechanism at described detection sensor successively.
Preferably, described urine analysis system, wherein, the shell of described Urine Analyzer is in hand-held shape, its top
There is display screen, this shell is provided with absorption sample button, unloads button, and this enclosure is provided with circuit board, battery；It passes through
Described connector is connected with described micro-fluidic chip, is provided with the electricity for unloading micro-fluidic chip at the side of described connector
Magnet and unload load arm；Described suction means and chip unloading device are using electric control mode.
Preferably, described urine analysis system, wherein, what described detection means included being connected with described connector turns
Galvanic electricity machine, the connection pump being connected by pipeline with described connector, located at the detection sensor of the side of described micro-fluidic chip.
The beneficial effects of the utility model：The urine analysis system of this case, makes the artificial behaviour of semi-automatic urine analysis system
Work part becomes the operation of manually installed micro-fluidic chip by the operation that artificial test strips dip in urine, makes indicator paper block immerse the pass of urine
Key step is changed into system and is automatically performed the concordance it is ensured that the response time, thus improving accuracy in detection, automatic using chip
The mode drawing urine infiltrates indicator paper block, without manual intervention, makes that the precision of semi-automatic urinalysiss is higher, accuracy is higher；
It is operable that this system does not need professional person.
Brief description
Accompanying drawing 1 is the structural representation of the urine analysis system described in this utility model one embodiment；
Accompanying drawing 2 is the micro-fluidic chip schematic diagram in the urine analysis system described in this utility model one embodiment；
Accompanying drawing 3 is the suction urine specimen schematic diagram of the urine analysis system described in this utility model one embodiment；
Accompanying drawing 4 is the reading test strips color scheme of the urine analysis system described in this utility model one embodiment；
Accompanying drawing 5 is the unloading micro-fluidic chip schematic diagram of the urine analysis system described in this utility model one embodiment；
Accompanying drawing 6 is the structural representation of the urine analysis system described in this utility model one embodiment；
Accompanying drawing 7 is that the first preferred embodiment of the micro-fluidic chip in urine analysis system described in the utility model is illustrated
Figure；
Accompanying drawing 8 is that the first preferred embodiment of the micro-fluidic chip in urine analysis system described in the utility model is three-dimensional
Installation diagram；
Accompanying drawing 9 is that the second preferred embodiment of the micro-fluidic chip in urine analysis system described in the utility model is illustrated
Figure；
Accompanying drawing 10 is that the second preferred embodiment of the micro-fluidic chip in urine analysis system described in the utility model is stood
Body installation diagram；
Accompanying drawing 11 is that the 3rd preferred embodiment of the micro-fluidic chip in urine analysis system described in the utility model is shown
It is intended to；
Accompanying drawing 12 is that the 3rd preferred embodiment of the micro-fluidic chip in urine analysis system described in the utility model is stood
Body installation diagram；
Accompanying drawing 13 is that the 4th preferred embodiment of the micro-fluidic chip in urine analysis system described in the utility model is shown
It is intended to；
Accompanying drawing 14 is that the 4th preferred embodiment of the micro-fluidic chip in urine analysis system described in the utility model is stood
Body installation diagram；
Accompanying drawing 15a is that the structure of the Urine Analyzer one in the urine analysis system described in this utility model one embodiment is shown
It is intended to；
Accompanying drawing 15b is the internal junction of the Urine Analyzer one in the urine analysis system described in this utility model one embodiment
Structure schematic diagram；
Accompanying drawing 15c is the three-dimensional dress of the Urine Analyzer one in the urine analysis system described in this utility model one embodiment
Join schematic diagram；
Accompanying drawing 15d is the structural representation of the detection means one in the urine analysis system described in this utility model one embodiment
Figure；
Accompanying drawing 16a is that the structure of the Urine Analyzer two in the urine analysis system described in this utility model one embodiment is shown
It is intended to；
Accompanying drawing 16b is the internal junction of the Urine Analyzer two in the urine analysis system described in this utility model one embodiment
Structure schematic diagram；
Accompanying drawing 16c is the structural representation of the detection means two in the urine analysis system described in this utility model one embodiment
Figure；
Accompanying drawing 17a is that the structure of the Urine Analyzer three in the urine analysis system described in this utility model one embodiment is shown
It is intended to；
Accompanying drawing 17b is the internal junction of the Urine Analyzer three in the urine analysis system described in this utility model one embodiment
Structure schematic diagram；
Accompanying drawing 17c is the three-dimensional dress of the Urine Analyzer three in the urine analysis system described in this utility model one embodiment
Join schematic diagram；
Accompanying drawing 17d is the structural representation of the detection means three in the urine analysis system described in this utility model one embodiment
Figure；
Accompanying drawing 18a is the structural representation of the detection means four in the urine analysis system described in this utility model one embodiment
Figure；
Accompanying drawing 18b is the internal structure of the detection means four in the urine analysis system described in this utility model one embodiment
Schematic diagram.
Specific embodiment
Below in conjunction with the accompanying drawings this utility model is described in further detail, to make those skilled in the art with reference to explanation
Book word can be implemented according to this.
A kind of urine analysis system, including：Including Urine Analyzer 10 and micro-fluidic chip 1, wherein,
Described micro-fluidic chip is provided with several urinalysiss indicator paper blocks 2, and with urinalysiss reagent paper each described
The fluid passage 3 that block correspondence communicates；With
Liquid flows into end 5, and it is located at described micro-fluidic chip lower end, and connects to described fluid passage one end；
Liquid outlet 4, it is located at described micro-fluidic chip upper end, and connects to the described fluid passage other end；
Described Urine Analyzer includes the detection probe 8 for detecting described urinalysiss indicator paper block, described for connecting
The connector 6 of micro-fluidic chip；And
Suction means 7, it passes through the described liquid outlet that described connector connects described micro-fluidic chip.
Further, the detection project of described urine analysis system includes but is not limited to urobilinogen, bilirubin, ketoboidies, Asia
Nitrate, erythrocyte, leukocyte esterase, proportion, pH value, protein, micro- albumin, glucose, ascorbic acid, creatinine, calcium,
Urine one of color and more than one.
Further, there is N bar described fluid passage, and is disposed with N number of urinalysiss reagent paper in described N bar fluid passage
Block, each described urinalysiss indicator paper block corresponds to a described fluid passage, described N be not less than 1 and no more than 15 integer；
And described urinalysiss indicator paper block is can to react with the urine specimen to be detected that flows through in described fluid passage to change
Color.
Further, two larger sides of described urinalysiss indicator paper block area, wherein have and adopt at least one side
Packing forms with printing opacity.
Further, two larger sides of described urinalysiss indicator paper block area, wherein have and adopt at least one side
With exposing aerial packing forms.
Further, described urinalysiss are read from described urinalysiss indicator paper block immersion urine to described detection probe
The time of indicator paper block color is 30 seconds -90 seconds.
Specifically, as shown in Fig. 2 urinalysiss indicator paper block 2 is encapsulated in micro-fluidic chip 1, have in micro-fluidic chip 1
Fluid passage 3, when the shape of fluid passage 3 makes to flow through urine specimen 11 to be detected inside it, each indicator paper block 2 is treated
The urine specimen 11 of detection immerses.Micro-fluidic chip 1 also has liquid and flows into end 5, liquid outlet 4.When carrying out urinalysiss,
First micro-fluidic chip 1 is inserted Urine Analyzer 10, so that the suction means 7 in Urine Analyzer 10 is connected by connector 6
Liquid outlet 4 to micro-fluidic chip 1.As shown in figure 3, urine specimen 11 to be tested is placed under Urine Analyzer 10
Side, makes the liquid suction side 5 of micro-fluidic chip 1 be immersed in urine specimen 11.Suction means 7 liquid draw of Urine Analyzer 10
Body, makes urine specimen 11 be inhaled in micro-fluidic chip 1, and immerses indicator paper block 2.As shown in figure 4, immersing examination in urine specimen
Chemical reaction in indicator paper block 2 completes paper block 2 afterwards within about 30 to 90 seconds, and the detection probe 8 of Urine Analyzer 10 moves to micro-
At fluidic chip 1, block-by-block reads the color of indicator paper block 2 in micro-fluidic chip 1.As shown in figure 5, the unloading in Urine Analyzer 10
Device 9 moves downward, and makes micro-fluidic chip 1 depart from Urine Analyzer 10.
In another embodiment of the present utility model, detection probe 8 be made into fixing, accordingly, micro-fluidic chip 1
Can be moved.In the present embodiment, micro-fluidic chip 1 is made into disc, cylindrical or truncated cone-shaped, Ke Yijin
Row circular motion, Fig. 6 show the situation of cylinder, and the indicator paper block that detection probe 8 is fixed on apart from micro-fluidic chip is close
Position, need read micro-fluidic chip 1 in indicator paper block 2 color when, make micro-fluidic chip 1 be rotated, you can to make detection
Probe 8 completes the color to all indicator paper blocks and reads.
Specific operating procedure detailed process is as shown in Fig. 2 to Fig. 6.As shown in Fig. 2 urinalysiss indicator paper block 2 is encapsulated
To in micro-fluidic chip 1, in micro-fluidic chip 1, there is fluid passage 3, the shape of fluid passage 3 makes to flow through sample liquid inside it
When 11, each indicator paper block 2 is immersed by sample liquid 11.Micro-fluidic chip 1 also has liquid and flows into end 5, liquid outlet
4.As shown in figure 3, when carrying out urinalysiss, first micro-fluidic chip 1 is inserted Urine Analyzer 10, make in Urine Analyzer 10
Suction means 7 be connected to the liquid outlet 4 of micro-fluidic chip 1 by connector 6.Operation herein can be by manually complete
Become.As shown in figure 4, being placed on urine specimen 11 to be tested below Urine Analyzer 10, make the liquid flow of micro-fluidic chip 1
Enter end 5 to be immersed in urine specimen 11.Liquid drawn by the suction means 7 of Urine Analyzer 10, so that urine specimen 11 is inhaled into
In micro-fluidic chip 1, and immerse indicator paper block 2.As shown in figure 5, after the completion of chemical reaction in indicator paper block 2, Urine Analyzer 10
Detection probe 8 move at micro-fluidic chip 1, block-by-block read micro-fluidic chip 1 in indicator paper block 2 color.As shown in fig. 6,
Discharge mechanism 9 in Urine Analyzer 10 moves downward, and makes micro-fluidic chip 1 depart from Urine Analyzer 10.Whole operation process
In, artificial operation part is only and micro-fluidic chip 1 is installed in Urine Analyzer 10, not only avoid and manually dips sample band
The time uncertainty coming, also makes the relatively sanitary safety of whole operation process.
As shown in Fig. 2 wherein micro-fluidic chip includes：Liquid flows into end 5, liquid outlet 4, connection described liquid inflow
The N bar fluid passage 3 of end and described liquid outlet is it is characterised in that N number of indicator paper block 2 is arranged in described N bar fluid passage 3
Interior, each described indicator paper block corresponds to a described fluid passage, and described indicator paper block can with described fluid passage in flow through
Liquid reacts and changes color.
Micro-fluidic chip 1 is inserted Urine Analyzer 10, makes the suction means 7 in Urine Analyzer 10
It is connected to the connection end 4 of micro-fluidic chip 1 by connector 6.Urine specimen 11 to be tested is placed on urine
Below analyser 10, the liquid suction side 5 of micro-fluidic chip 1 is made to be immersed in urine specimen 11.The absorption of Urine Analyzer 10
Device 7 draws liquid, so that urine specimen 11 is inhaled in micro-fluidic chip 1, and immerses indicator paper block 2.Chemistry in indicator paper block 2
After the completion of reaction, the detection probe 8 of Urine Analyzer 10 moves at micro-fluidic chip 1, and block-by-block reads examination in micro-fluidic chip 1
The color of paper block 2.Discharge mechanism 9 in Urine Analyzer 10 moves downward, and makes micro-fluidic chip 1 depart from Urine Analyzer 10.
Wherein, the detection probe 8 of Urine Analyzer 10, can be actionless, and micro-fluidic chip 1 now can be made to transport
Dynamic, thus realizing the color that block-by-block reads indicator paper block 2 in micro-fluidic chip 1.
In one preferred embodiment of the micro-fluidic chip in urine analysis system of the present utility model, micro-fluidic chip quilt
Make rectangularity, fluid passage number N=6, its structure three-dimensional model is as shown in Figure 8 (for making the mutual relation of in figure each several part
Embodiment that can be apparent, this figure employs transparent manifestation mode to part), liquid flows into end 5 and has stream for inside
Through hole external shape is similar to the strip catheter of bullet shaped, and liquid outlet 4 has outside larger sectional area opening for inside
Portion is shaped as square block part.6 fluid passages 3 of micro-fluidic chip 1, its make can be as three-dimensional installation diagram；
As shown in figure 9, micro-fluidic chip 1 is by transparent sheet 101, lamella 102, lamella 103 mutually bonds and makes, and fluid passage 3 is divided
It is slit into the passage 301 positioned at lamella 102, positioned at the passage 302 of lamella 102, and be located at lamella 103 303.Indicator paper block 2
At lamella 102.In process, the passage 301 on lamella 102, passage 302 and the square hole installing indicator paper block 2, in thickness
Insertion is on direction, and the passage 303 on lamella 103, not insertion on the thickness direction of lamella.In actually used process
In, sample liquid, after liquid flows into end 5 entrance micro-fluidic chip 1, through 303 sections of 301 sections of inflows of fluid passage 3, then flows
Enter 302 sections, flow out from liquid outlet 4, sample liquid contacts indicator paper block 2 in 303 sections of flow process, so that indicator paper block 2 is occurred
Chemical reaction variable color.In this embodiment, detection project representated by 6 indicator paper blocks can for urine protein, microdose urine protein,
Glucose, ketoboidies, pH value, proportion.For those skilled in the art, can lamella 101 in this utility model embodiment, piece
Layer 102, on the basis of lamella 103, using technological means customary in the art, you can with the fluid incomplete same with the present embodiment
The form of expression of passage completes identical technique effect, such as provides for simple replacement of the position of lamella 101 and lamella 103, by passage portion
Be placed in the lamella differing with the present embodiment etc., all should be regarded as equivalent the present embodiment.
In second preferred embodiment of the micro-fluidic chip in urine analysis system of the present utility model, micro-fluidic chip quilt
It is fabricated to disc, fluid passage number N=5, its structure three-dimensional model is as shown in Figure 10 (for making the mutual relation of in figure each several part
Embodiment that can be apparent, this figure employs transparent manifestation mode to part), liquid flows into end 5 and has stream for inside
Through hole external shape is similar to the strip catheter of bullet shaped, and liquid outlet 4 has outside larger sectional area opening for inside
The cylindrically shaped cylindrical parts in portion.5 fluid passages 3 of micro-fluidic chip 1, its make can be as three-dimensional assembling
Figure；As shown in figure 11, by lamella 104, lamella 105, transparent sheet 106 mutually bonds and makes micro-fluidic chip 1, fluid passage 3
It is divided into the passage 304 positioned at lamella 104, positioned at the passage 305 of lamella 105, and be located at lamella 106 306.Indicator paper block
2 are located at lamella 105.In process, the passage 305 on lamella 105 and the square hole installing indicator paper block 2, in thickness direction
On be insertion, and the passage 306 on the passage 304 on lamella 104, and lamella 106, on the thickness direction of lamella not
Insertion.In actual use, sample liquid from liquid flow into end 5 enter micro-fluidic chip 1 after, through fluid passage 3
304 sections flow into 305 sections, then flow into 306 sections, flow out from liquid outlet 4, sample liquid contacts examination in 304 sections of flow process
Paper block 2, makes indicator paper block 2 that chemical reaction variable color to occur.In this embodiment, the detection project representated by 5 indicator paper blocks can be
Urine is occulted blood, leukocyte esterase, nitrite, urobilinogen, bilirubin.For those skilled in the art, can be in this utility model
Lamella 104 in embodiment, lamella 105, on the basis of lamella 106, using technological means customary in the art, you can with this reality
The form of expression applying the incomplete same fluid passage of example realizes identical technique effect, such as provides for simple replacement of lamella 104 and lamella
106 position, passage portion is placed in the lamella being differed with the present embodiment etc., all should be regarded as equivalent the present embodiment.
In 3rd preferred embodiment of the micro-fluidic chip in urine analysis system of the present utility model, micro-fluidic chip quilt
It is fabricated to cylinder, fluid passage number N=15, its structure three-dimensional model is as shown in figure 12 (for making the mutual pass of in figure each several part
System can be apparent embodiment, this figure employs transparent manifestation mode to part), liquid flows into end 5 to be had for inside
Opening external shape is the strip catheter of cylinder, and liquid outlet 4 has outside larger sectional area opening for inside
Cylindrically shaped.15 fluid passages 3 of micro-fluidic chip 1, its make can be as three-dimensional installation diagram；As Figure 13 institute
Show, by bottom 107, intermediate layer 108, top layer 109 mutually bonds and makes micro-fluidic chip 1, liquid flows into end 5 and bottom 107 quilt
It is fabricated to a part, liquid outlet 4 and top layer 109 are made into a part, during bottom 107 also has and can surround
The transparent circular side wall 110 of interbed 108.Fluid passage 3 is made into the passage of the lower surface being located immediately at intermediate layer 108
307th, the passage 309 of the passage 308 of side surface and upper surface.Indicator paper block 2 be located at intermediate layer 108 side at and with passage 308
Contact.In actual use, sample liquid from liquid flow into end 5 enter micro-fluidic chip 1 after, through fluid passage 3
308 sections of 307 sections of inflows, then flow into 309 sections, flow out from liquid outlet 4, sample liquid contacts in 308 sections of flow process
Indicator paper block 2, makes indicator paper block 2 that chemical reaction variable color to occur.In this embodiment, the detection project representated by 15 indicator paper blocks is permissible
For urine occult blood, leukocyte esterase, nitrite, urobilinogen, bilirubin, urine protein, microdose urine protein, glucose, ketoboidies, PH
Value, proportion, color.For those skilled in the art, can bottom 107 in this utility model embodiment, intermediate layer 108,
On the basis of top layer 109, using technological means customary in the art, you can with the fluid passage incomplete same with the present embodiment
The form of expression realizes identical technique effect, is such as simply changed to the annular sidewall 110 of bottom 107 at top layer 109 or straight
Connect and annular sidewall 110 part is fabricated to a single part, or the passage on intermediate layer 108 is placed in and this reality
Apply the top layer 109 that example differs, in bottom 107 etc., all should be regarded as being equal to the present embodiment.
In 4th preferred embodiment of the micro-fluidic chip in urine analysis system of the present utility model, micro-fluidic chip quilt
It is fabricated to truncated cone-shaped, fluid passage number N=15, its structure three-dimensional model is as shown in figure 14 (for making the mutual pass of in figure each several part
System can be apparent embodiment, this figure employs transparent manifestation mode to part), liquid flows into end 5 to be had for inside
Opening external shape is the strip catheter of cylinder, and liquid outlet 4 has outside larger sectional area opening for inside
Cylindrically shaped.15 fluid passages 3 of micro-fluidic chip 1, its make can be as three-dimensional installation diagram；As Figure 15 institute
Show, by bottom 111, intermediate layer 112, top layer 113 mutually bonds and makes micro-fluidic chip 1, liquid flows into end 5 and bottom 111 quilt
It is fabricated to a part, liquid outlet 4 and top layer 113 are made into a part, and top layer 113 also has corresponding to each
The window 114 of indicator paper block 2.Fluid passage 3 be made into be located immediately at the passage 307 of intermediate layer 112 lower surface, side surface logical
The passage 309 of road 308 and upper surface.Indicator paper block 2 is located at the side in intermediate layer 112 and is contacted with passage 308.Make actual
With during, sample liquid flows into after end 5 enters micro-fluidic chip 1 from liquid, through 307 sections of fluid passage 3 inflows 308
Section, then flow into 309 sections, flow out from liquid outlet 4, sample liquid contacts indicator paper block 2 in 308 sections of flow process, makes reagent paper
There is chemical reaction variable color in block 2.In this embodiment, the detection project representated by 15 indicator paper blocks can occult blood for urine, thin in vain
Born of the same parents' esterase, nitrite, urobilinogen, bilirubin, urine protein, microdose urine protein, glucose, ketoboidies, pH value, proportion, color.
For those skilled in the art, can bottom 111 in this utility model embodiment, intermediate layer 112, top layer
On the basis of 113, using technological means customary in the art, you can with the performance of the fluid passage incomplete same with the present embodiment
Form realizes identical technique effect, and the such as simple window structure by top layer 113 is cancelled, and is changed to directly adopt transparent material,
Or the upper strata of truncated conical shape, lower floor are mutually exchanged, all should be regarded as being equal to the present embodiment.
A preferred embodiment such as Figure 16 a, 16b, 16c of Urine Analyzer in urine analysis system of the present utility model
Shown, in the present embodiment, using rectangle micro-fluidic chip, accordingly, Urine Analyzer be shaped as cuboid.This enforcement
The Urine Analyzer 10 of example, is top and sidepiece shell 1001, bottom enclosure 1003 outside it, top also has display screen
1002nd, sampling button 701 and unloading button 901, wherein, sampling button 701 connects suction means 702 directly below；Unloading is pressed
Key 901 connects discharge mechanism 902 directly below；Suction means 702 is fabricated to a cylindrical structural, embedding on discharge mechanism 902
It is enclosed within the outside of the suction means 702 of cylinder, and connect a spring assembly；Suction means 702 passes through internal pipeline
It is connected with connector 601；When actually used, by gap in the middle of Urine Analyzer bottom enclosure 1003 for the micro-fluidic chip 1
Insertion Urine Analyzer, makes the liquid outlet 4 at micro-fluidic chip 1 top is connected with connector 601.Detection means 8 is arranged
In the side of micro-fluidic chip 1, main circuit board 807 is fixed on 801 sides of framework, the linear electric motors 802 with leading screw and two
What sliding guide 806 was parallel is arranged in inside framework 801, walking circuit plate 803 across two interactive guide rods 806 and with band leading screw
Linear electric motors 802 be connected, detection sensor 805 is arranged on walking circuit plate 803, walking circuit plate 803 pass through flexibility
Winding displacement 804 is connected to main circuit board 807.During carrying out test sample, the linear electric motors 802 with leading screw run, and drive
Walking circuit plate 803 and detection sensor 805 move along the direction of sliding guide 806.In the present embodiment, use is rectangular
Shape micro-fluidic chip 1, its internal indicator paper block 2 is arranged in order in a row, and is exactly in the mobile route of detection sensor 805
Side.Detection sensor 805, during movement, is successively read the color data of each indicator paper block 2.
Second preferred embodiment such as Figure 17 a of the Urine Analyzer in urine analysis system of the present utility model, 17b,
Shown in 17c, in the present embodiment, Urine Analyzer 10 is made into the shape of hand-held pipettor, accordingly, disc miniflow
Chip 1 is interchangeable in the way of pipetting head is arranged on Urine Analyzer 10 bottom for control.It is made into the shell of pipettor shape
1005, its top-side is integrated with main electric component 1004, and main electric component 1004 at least should include circuit board it is also possible to include
Button and display screen, battery and wireless link block.It is disposed with detection probe 8 inside the casing part 1006 of bottom.Herein
The mode that detection probe 8 and detection head in first embodiment read indicator paper block color at the volley one by one is different, employs
Detection sensor and the one-to-one mode of indicator paper block, arrangement and reagent paper number of blocks identical detection sensor.Urine Analyzer
10 top is provided with the button of two convenience thumb operations, is the sampling button being directly connected to suction means 704 respectively
703, and it is directly connected to the unloading button 903 of discharge mechanism 904.What discharge mechanism 904 was concentric is set in suction means 704
Outside.The bottom of suction means 704 can be connected with micro-fluidic chip 1 directly as connector 602.Using the present embodiment
Urine Analyzer when carry out urinalysiss, user can start the electric part of Urine Analyzer, then will be micro-fluidic
Chip installs the bottom into Urine Analyzer, then single hand grip Urine Analyzer, by Urine Analyzer bottom micro-fluidic chip
Liquid flow in end immersion urine to be detected, thumb pressing sampling button makes urine specimen be inhaled into micro-fluidic chip
Interior, wait for a period of time, reaction completes and Urine Analyzer completes indicator paper block color and reads, and obtains testing result；Hereafter permissible
Single hand grip Urine Analyzer, thumb press unloads button, and this used micro-fluidic chip can be made to depart from urinalysiss
Instrument.
3rd preferred embodiment such as Figure 18 a, 18b institute of the Urine Analyzer in urine analysis system of the present utility model
Show., using cylinder, the detection means 8 within Urine Analyzer 10 is partly complex, has a rotating machine for micro-fluidic chip 1
Structure, can make micro-fluidic chip 1 rotate motion, so that the indicator paper block in micro-fluidic chip 1 moves to detection successively and passes
At sensor 810.The Urine Analyzer 10 of the present embodiment includes shell 1007, keyboard and circuit board 1008, display screen 1009, prints
Module 1010, electrically driven (operated) suction means 705, connector 603, discharge mechanism 905, and there is the detection of the present embodiment feature
Device 8.The detection means 8 of the present embodiment, including the detection sensor 810 of only one piece of sensor, drives micro-fluidic chip to turn
Dynamic motor 808, and travelling gear 809.
In the fourth embodiment of Urine Analyzer of the present utility model, Urine Analyzer is made into as Figure 18 a, 18b institute
The shape of the hand-held electronic clinical thermometer showing.The present embodiment adopts round table-like micro-fluidic chip.The shell of Urine Analyzer
1011 shapes with hand-held electronic clinical thermometer, its top has display screen 1012, and handle leading portion has absorption sample button
706, and unloading button 906, there are circuit board 1013, battery 1014 inside handle portion.Instrument internal is direct with micro-fluidic chip 1
Be connected is connector 604, and connector 604 is directly connected to rotary electric machine 811, and connector 604 connects pump 707 by pipeline,
The side of micro-fluidic chip 1 is provided with detection sensor 812.It is provided with for unloading micro-fluidic chip 1 at the side of connector 604
Electric magnet 907 and unload load arm 908.In the present embodiment, suction means 7 and chip unloading device 9 all employ electric manipulation side
Formula.
It should be noted that this case (arranges multiple including but not limited to micro-fluidic chip with detection means geo-stationary
Sensor, and sensor and indicator paper block correspond), detection means is static and micro-fluidic chip moves with respect to detection means,
Micro-fluidic chip is static and detection means with respect to micro-fluidic chip move these three modes so that urinalysiss indicator paper block one by one
Detected, wherein, sensor in detection means moves, can be rectilinear movement it is also possible to rotary motion；Chip motion
Scheme is also the same, is all rotary motion, actual design can also be that strip chip moves along a straight line inside above-described embodiment.
Aforesaid way each falls within the protection domain of this case, and for example, detection project is less, it is possible to use multiple sensors and micro-fluidic core
The scheme of piece geo-stationary；More than detection project, can according to instrument outward appearance and structure design, select the mobile scheme of sensor or
It is micro-fluidic chip motion scheme.Such scheme is combined or alternative design, is all the usual of those skilled in the art
Technological means.
Above-described embodiment of Urine Analyzer of the present utility model, suction means therein, detection probe, discharge mechanism,
There is the form of expression differing, those skilled in the art can simply carry out related replacement and combine, you can obtain one newly
Technical scheme, for example second embodiment shape as pipettor Urine Analyzer in, using electrically driven (operated) suction means, or
Using electrically driven (operated) discharge mechanism, such, all should be regarded as being equal to the technical solution of the utility model.
Although embodiment of the present utility model is disclosed as above, it is not restricted in description and embodiment
Listed utilization, it can be applied to various suitable fields of the present utility model completely, for those skilled in the art,
It is easily achieved other modification, therefore under the general concept being limited without departing substantially from claim and equivalency range, this reality
It is not limited to specific details with new and shown here as the legend with description.
Claims (19)
1. a kind of urine analysis system is it is characterised in that include：Urine Analyzer and micro-fluidic chip, wherein, described micro-fluidic
Chip is provided with several urinalysiss indicator paper blocks, and the fluid that communicate corresponding with urinalysiss indicator paper block each described leads to
Road；With
Liquid flows into end, and it connects to described fluid passage one end；
Liquid outlet, it connects to the described fluid passage other end；
Described Urine Analyzer includes the detection means for detecting described urinalysiss indicator paper block, described micro-fluidic for connecting
The connector of chip；And suction means, it connects described liquid outlet.
2. urine analysis system as claimed in claim 1 is it is characterised in that the detection project of described urine analysis system includes
But it is not limited to urobilinogen, bilirubin, ketoboidies, nitrite, erythrocyte, leukocyte esterase, proportion, pH value, protein, micro- white egg
In vain, glucose, ascorbic acid, creatinine, calcium, urine one of color and more than one.
3. urine analysis system as claimed in claim 2 is it is characterised in that there is N bar described fluid passage, and in described N bar
It is disposed with N number of urinalysiss indicator paper block, each described urinalysiss indicator paper block corresponds to a described fluid passage in fluid passage,
Described N be not less than 1 and no more than 15 integer；And described urinalysiss indicator paper block can with described fluid passage in flow through
Urine specimen to be detected reacts and changes color.
4. urine analysis system as claimed in claim 3 it is characterised in that described urinalysiss indicator paper block area larger two
, wherein there are the packing forms adopting printing opacity at least one side individual side.
5. urine analysis system as claimed in claim 4 it is characterised in that described urinalysiss indicator paper block area larger two
Individual side, wherein has at least one side using exposing aerial packing forms.
6. urine analysis system as claimed in claim 3 is it is characterised in that described micro-fluidic chip is oblong-shaped, and institute
State parallel being distributed on described micro-fluidic chip in fluid passage.
7. urine analysis system as claimed in claim 3 is it is characterised in that described micro-fluidic chip is disc-shape, and institute
State that fluid passage is radial to be distributed on described micro-fluidic chip.
8. urine analysis system as claimed in claim 3 is it is characterised in that described micro-fluidic chip is cylindrical shape, and institute
State the side that urinalysiss indicator paper block is distributed in described cylinder.
9. urine analysis system as claimed in claim 3 is it is characterised in that described micro-fluidic chip is truncated conical shape, and institute
State the side that urinalysiss indicator paper block is distributed in described round platform.
10. urine analysis system as claimed in claim 1 is it is characterised in that described Urine Analyzer also includes one is used for
The discharge mechanism of unloading micro-fluidic chip.
11. urine analysis systems as claimed in claim 10 are it is characterised in that described detection means is located at described micro-fluidic core
The side of piece, it includes a moveable detection sensor.
12. urine analysis systems as claimed in claim 10 are it is characterised in that described detection means includes N number of detection sensing
Device, that is, described detection sensor quantity is identical with described urinalysiss reagent paper number of blocks.
13. urine analysis systems as claimed in claim 10 are it is characterised in that described detection means includes a detection sensing
Device and a machinery driving described micro-fluidic chip motion；Described detection sensor is used for gathering described urinalysiss examination
The color data of paper block.
14. urine analysis systems as claimed in claim 10 are it is characterised in that described Urine Analyzer also includes top and side
Portion's shell, bottom enclosure, its top is additionally provided with display screen, sampling button and unloading button, wherein, connects below described sampling button
It is connected to suction means；It is also associated with described discharge mechanism below described unloading button；Described suction means is cylindrical structural, institute
State the outside that discharge mechanism is nested in described suction means；Described suction means is by its internal pipeline and described connector phase
Connect.
15. urine analysis systems as claimed in claim 10 are it is characterised in that described detection means is located at described micro-fluidic core
The side of piece, described detection means also includes：Main circuit board is fixed on framework side, the linear electric motors with leading screw and two slip
What guide rod was parallel is arranged in lower portion, and walking circuit plate is connected across two interactive guide rods and with the linear electric motors with leading screw
Connect, described detection sensor is arranged on walking circuit plate, walking circuit plate is connected to main circuit board by flexible winding displacement.
16. urine analysis systems as claimed in claim 10 are it is characterised in that described Urine Analyzer is in hand-held pipettor
Shape, including top casing, bottom enclosure, the side of described top casing is integrated with main electric component, and this main electric component includes
Circuit board, button and display screen, battery and wireless link block；The top of described Urine Analyzer is additionally provided with connection and draws
The sampling button of device, and connect the unloading button of described discharge mechanism；What this discharge mechanism was concentric is set in described absorption
The outside of device；The bottom of described suction means is connected with micro-fluidic chip as connector.
17. urine analysis systems as claimed in claim 10 are it is characterised in that described detection means includes sensing containing one piece
The detection sensor of device, for the motor driving described micro-fluidic chip to rotate, travelling gear, also include one be used for making described
Micro-fluidic chip rotates motion, makes described indicator paper block move to the rotating mechanism at described detection sensor successively.
18. urine analysis systems as claimed in claim 10 are it is characterised in that the shell of described Urine Analyzer is in hand-held
Shape, its top has display screen, and this shell is provided with absorption sample button, unloads button, and this enclosure is provided with circuit board, electricity
Pond；It is connected with described micro-fluidic chip by described connector, is provided with for unloading miniflow at the side of described connector
Control the electric magnet of chip and unload load arm；Described suction means and chip unloading device are using electric control mode.
19. urine analysis systems as claimed in claim 10 are it is characterised in that described detection means includes and described connector
The rotary electric machine connecting, the connection pump being connected by pipeline with described connector, located at the inspection of the side of described micro-fluidic chip
Survey sensor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620541178.1U CN205991901U (en) | 2016-06-06 | 2016-06-06 | A kind of urine analysis system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620541178.1U CN205991901U (en) | 2016-06-06 | 2016-06-06 | A kind of urine analysis system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205991901U true CN205991901U (en) | 2017-03-01 |
Family
ID=58102970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620541178.1U Withdrawn - After Issue CN205991901U (en) | 2016-06-06 | 2016-06-06 | A kind of urine analysis system |
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| Country | Link |
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| CN (1) | CN205991901U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105890927A (en) * | 2016-06-06 | 2016-08-24 | 长春小孚科技有限公司 | Urine analysis system and method |
| WO2019061218A1 (en) * | 2017-09-28 | 2019-04-04 | 珠海沃姆电子有限公司 | Urine parameter measuring device and urine parameter monitoring system |
| CN110068695A (en) * | 2019-04-19 | 2019-07-30 | 成都恩普生医疗科技有限公司 | A kind of handheld portable urine automabic analyzer device device |
-
2016
- 2016-06-06 CN CN201620541178.1U patent/CN205991901U/en not_active Withdrawn - After Issue
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105890927A (en) * | 2016-06-06 | 2016-08-24 | 长春小孚科技有限公司 | Urine analysis system and method |
| CN105890927B (en) * | 2016-06-06 | 2019-05-07 | 深圳小孚医疗科技有限公司 | A kind of urine analysis system and its urinalysis method |
| WO2019061218A1 (en) * | 2017-09-28 | 2019-04-04 | 珠海沃姆电子有限公司 | Urine parameter measuring device and urine parameter monitoring system |
| CN110068695A (en) * | 2019-04-19 | 2019-07-30 | 成都恩普生医疗科技有限公司 | A kind of handheld portable urine automabic analyzer device device |
| CN110068695B (en) * | 2019-04-19 | 2024-02-06 | 成都恩普生医疗科技有限公司 | Handheld portable automatic urine analysis instrument device |
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Effective date of registration: 20170728 Address after: 518172, Room 401, building B, building 2, Tian Xin Digital Town, Huang Bei Road, Longgang District, Shenzhen, Guangdong Patentee after: Shenzhen Fu Fu Medical Technology Co., Ltd. Address before: 130000 Changchun high tech Industrial Development Zone, Silicon Valley street, Yitian, Silicon Valley,, No. 5641 Chuang Chuang Chuang B block, room Patentee before: Changchun Xiaofu Technology Co., Ltd. |
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Granted publication date: 20170301 Effective date of abandoning: 20190507 |