CN205965110U - Chromatogram pillar support - Google Patents

Chromatogram pillar support Download PDF

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Publication number
CN205965110U
CN205965110U CN201620940094.5U CN201620940094U CN205965110U CN 205965110 U CN205965110 U CN 205965110U CN 201620940094 U CN201620940094 U CN 201620940094U CN 205965110 U CN205965110 U CN 205965110U
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CN
China
Prior art keywords
chromatographic column
net
frame
spacing hole
post position
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn - After Issue
Application number
CN201620940094.5U
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Chinese (zh)
Inventor
胡威
姜建
纪广辉
翟烁
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhongke Biopharm Co Ltd
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Zhongke Biopharm Co Ltd
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Publication date
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Priority to CN201620940094.5U priority Critical patent/CN205965110U/en
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Publication of CN205965110U publication Critical patent/CN205965110U/en
Withdrawn - After Issue legal-status Critical Current
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Abstract

The utility model relates to a chromatogram pillar support, this chromatogram pillar support includes the support, sets up the post bit slice net in a plurality of spacing holes and sets up the bottom plate of a plurality of pipeline pipe fittings export, wherein, spacing hole includes the aperture of multiple specification, and just the aperture in spacing hole all is greater than the maximum diameter at corresponding specification chromatographic column both ends, two piece at least post bit slices net is installed on the support along vertical direction parallel interval, and the position in each online spacing hole of post bit slice distributes and keeps unanimous, the bottom plate is on a parallel with post bit slice entoilage to be fixed in support bottom, and is located the below of post bit slice net bottom, and the position of the pipeline pipe fitting export on the bottom plate distributes and the position distribution phase in post bit slice online spacing hole corresponds. The utility model discloses a chromatogram pillar support, the post bit slice that has a plurality of spacing holes through the adoption is netted, can place many chromatographic column an organic wholes of many specifications, effectively saves the parking space of chromatographic column, makes chromatogram pillar support's bottom area increase simultaneously, need not additionally consider the problem of stability.

Description

Chromatographic column frame
Technical field
This utility model is related to the auxiliary device in a kind of chromatogram purification technique, more particularly, to a kind of chromatographic column frame.
Background technology
Also known as chromatographic technique, operation principle is to be filled in the medium with certain attribute (referred to as fixing phase) to chromatographic technique In cylindric straight tube (referred to as chromatographic column or chromatographic column, as shown in Figure 1), then using sample to be purified and various buffer solvent as stream Dynamic mutually pass sequentially through fixing phase, according to the different attribute of fixing phase, sample to be purified can be according to size, electric charge, the physics such as hydrophobic The difference of chemical property and separated, and flow out chromatographic columns, the solution of selection different phase by different sequencings The less target substance of range of attributes just can be obtained, thus reaching the purpose of purification.Wherein, the medium of chromatographic column and wherein filling Play a major role during isolating and purifying.
Chromatographic column needs to use auxiliary device chromatographic column frame when using, and the function of chromatographic column frame is exactly to make chromatographic column vertical Place, and ensure the safety of chromatographic column during using and depositing.Large-scale chromatographic column volume mass is larger, typically all carries post Frame, is readily transported movement;Laboratory room small-sized chromatographic column does not typically all have pylon, adopts the support of iron stand etc or is faced with clip When fix;Medium chromatographic column may choose whether configure pylon.Regardless of chromatographic column, pylon is all very big in chromatographic column cost Part, even above chromatographic column cost.Import pylon typically adopts solid high-quality steel, and therefore price is higher;Some domestic posts Frame adopts light hollow steel, can only substantially keep the vertical state of chromatographic column, there is the potential safety hazard toppled over, and stationarity is owed Good.
It is often necessary to purification is studied using the medium of different attribute in the research process of biological product and protein drug Technique, meanwhile, different preparation batches is also required to the chromatographic column of different size, and such laboratory is accomplished by preparing many different rule Lattice and the chromatographic column of filling different medium.But existing chromatographic column frame is both for the single chromatographic column of single specification and sets Meter, general using vertically single stationary chromatographic post, such as Fig. 2 (a), (b) and Fig. 3 on the slightly larger base of the area of three feet or four feet Shown in (a), (b).The leg of typically common single pylon can expand to floor space be not less than 25cm*25cm scope or with On, to ensure the stability of chromatographic column frame, many root chromatogram columns all can take too many space using single pylon, and also needs to Consider the stable problem that each chromatographic column is placed.
Content of the invention
For the problems referred to above, the purpose of this utility model is to provide a kind of chromatographic column frame, is that the many root chromatogram columns of many specifications carry For the deposit position of one, effectively save parking space, and do not need to provide exceptional space for stable with base.
For achieving the above object, this utility model takes technical scheme below:A kind of chromatographic column frame is it is characterised in that be somebody's turn to do Chromatographic column frame includes:Support, the post position offering multiple spacing holes limits net, and the bottom offering multiple pipe fitting outlets Plate;Wherein, described spacing hole includes the aperture of plurality of specifications, and the aperture of described spacing hole is all higher than corresponding specification chromatographic column two The maximum gauge at end;At least two pieces described post positions limit net, and vertically parallel interval is installed on the bracket, and each institute The position distribution stating the online described spacing hole of post position restriction is consistent;It is solid that described base plate limits entoilage parallel to described post position It is scheduled on described frame bottom, and be located at the lower section that the described post position of bottom limits net, the described pipe fitting on described base plate The position distribution that the position distribution of outlet limits online described spacing hole with described post position is corresponding.
Described support is frame support, limits net and base plate using the described post position of space frame structure fixation;Described post position The described spacing hole limiting net is sealing type, and the edge of described spacing hole has square groove.
Bracing strut centered on described support, described center bracing strut includes central shaft base and is vertically arranged in described center The central shaft at axle base center, described post position limits net and base plate center is fixedly mounted on described central shaft.
Frame support centered on described support, described center frame support includes central frame base and around described center The center vertical of frame base is arranged on the many root posts on described central frame base, and described post position limits net and base plate is installed On described column, form central frame structure.
The spacing hole that described post position limits network edge adopts open type to design, and in the opening both sides of described spacing hole respectively The fixing via hole of setting chromatographic column and constraint chain, described constraint chain is to be fixed on described chromatographic column admittedly by wire rope handling or the turn of the screw Determine the rope in via hole or chain.
The edge that described post position limits wide-aperture spacing hole on the net excavates out the small-bore of multiple open types further Spacing hole, and the opening both sides of the spacing hole in described small-bore are respectively provided with the fixing via hole of chromatographic column and constraint chain.
Directly over described base plate, 1 centimeters fixedly mount the described post position restriction net of bottom, just go up in described base plate At 1 meter of side, the described post position of fixed installation the top limits net.
Limit nets topmost installing multiple identical described post positions additional and the described post position restriction net of bottom between, Installing, positioned at middle described post position restriction, the single-column supporting plate that single chromatographic column can be held up on the net additional simultaneously;It is located at the described of centre The position that post position limits net being capable of up-down adjustment.
Described base plate limits, with described post position, the size netted and specification is identical.
The bottom of described chromatographic column frame is additionally provided with universal wheel.
Due to taking above technical scheme, it has advantages below to this utility model:1st, chromatographic column frame of the present utility model, By net is limited using the post position with multiple spacing holes, many root chromatogram column one of many specifications can be placed, effectively save The parking space of chromatographic column, makes the bottom area of chromatographic column frame increase simultaneously, without the extra problem considering stability.2nd, this reality With new chromatographic column frame, according to " chopsticks cannot vertically be placed, and the chopsticks being bundled into just can easily be holded up " Principle, while effectively strengthening chromatographic column frame stability, can also reduce the requirement to chromatographic column frame material, significantly reduce into This.3rd, chromatographic column frame of the present utility model, including the support of multiple fixed forms, can be according to actual stability and ease for use Need, select specific chromatographic column frame structure, range of application is more extensive.
Brief description
Fig. 1 is the structural representation of chromatographic column;
Fig. 2 (a), (b) are the use state figure of the simple pylon of tradition respectively;
Fig. 3 (a), (b) are the use state figure of traditional standard pylon respectively;
Fig. 4 (a), (b) are that this utility model adopts use state figure during frame support respectively;
Fig. 5 is the structural representation of this utility model frame support;
Fig. 6 is that this utility model adopts post position during frame support to limit the structural representation of net;
Fig. 7 is the structural representation that this utility model adopts base plate during frame support;
Fig. 8 (a), (b) are the use state figure that this utility model adopts during the bracing strut of center respectively;
Fig. 9 is the structural representation of this utility model center bracing strut;
Figure 10 is the structural representation that when this utility model adopts center bracing strut, post position limits net;
Figure 11 is the structural representation of base plate when this utility model adopts center bracing strut;
Figure 12 (a), (b) are the use state figure that this utility model adopts during the frame support of center respectively;
Figure 13 is the structural representation of this utility model center frame support;
Figure 14 is the structural representation that when this utility model adopts center frame support, post position limits net;
Figure 15 is the structural representation of base plate when this utility model adopts center frame support.
Specific embodiment
With reference to the accompanying drawings and examples this utility model is described in detail.
As shown in Fig. 4 (a), (b), Fig. 8 (a), (b) and Figure 12 (a), (b), the chromatographic column frame 100 that this utility model provides, It includes support 1, post position limits net 2 and base plate 3, according to stability and ease for use, selects the support 1 of different fixed forms.
Wherein, as shown in Fig. 6, Figure 10 and Figure 14, post position limit net 2 on offer multiple for placing chromatographic column 200 Spacing hole 21, spacing hole 21 includes multiple aperture, and the spacing hole 21 in aperture of different sizes is respectively used to place the different color of thickness Spectrum post 200, the aperture of spacing hole 21 is slightly larger than the maximum gauge at chromatographic column 200 two ends, spacing to ensure that chromatographic column 200 can be put into In hole 21 and be limited in the range of spacing hole 21, at least 2 pieces post positions limit net 2, and vertically parallel interval is fixed on On frame 1, and the position distribution of the spacing hole 21 on each post position restriction net 2 should be consistent, to guarantee to be limited in chromatographic column 200 Vertical state;Post position limits the quantity of different pore size spacing hole 21 opening up on net 2 and putting position can specifically set as needed Put, and the diameter reasonable arrangement according to different chromatographic columns 200, to guarantee to place more chromatographic columns 200 in less area.
As shown in Fig. 7, Figure 11 and Figure 15, base plate 3 offers multiple pipe fitting outlets 31, base plate 3 is parallel to post position Limit net 2 ground and be fixed on support 1 bottom, and be located at the post position of bottom and limit below net 2, be used for bearing all chromatographic columns 200 Weight, the position distribution in the position distribution and post position restriction net 2 upper limit hole 21 of pipe fitting outlet 31 on base plate 3 is relative Should.
In above-described embodiment, if Fig. 4 (a), (b) are with shown in Fig. 5, support 1 can be frame support 11, using space framework Structure fixed column position limits net 2 and base plate 3, and structure is more stable, and material requirements is low;Due to the obstruction of frame support 11 surrounding, Chromatographic column 200 need to be inserted from the top of chromatographic column frame 100 by chromatographic column frame 100 when using.As shown in fig. 6, propping up with shaped as frame The spacing hole 21 that the post position that frame 11 uses cooperatively limits net 2 is sealing type, and the edge of spacing hole 21 has square groove 22, with Just the interface of chromatographic column 200 side passes through.
In above-described embodiment, if Fig. 8 (a), (b) are with shown in Fig. 9~Figure 11, support 1 can also be center bracing strut 12, bag The central shaft 122 including central shaft base 121 and being vertically arranged in central shaft base 121 center, post position restriction net 2 and base plate 3 Center opens up restricted net central shaft installing hole 23 and base plate center axis installing hole 32 respectively, and post position limits net 2 and base plate 3 difference It is fixedly mounted on central shaft 122 by limiting net central shaft installing hole 23 and base plate center axis installing hole 32 center, due to adopting Fixing with central shaft 122, the material requirements to central shaft 122 is slightly higher.
In above-described embodiment, if Figure 12 (a), (b) are with shown in Figure 13~Figure 15, support 1 can also be center frame support 13, including central frame base 131 with around on the centrally disposed frame base 131 of central frame base 131 center vertical Many root posts 132, the edge certain distance away from central frame base 131 for many root posts 132, post position limits to be divided on net 2 and base plate 3 Do not offer the restriction net column mounting holes 24 corresponding with the position distribution of column 132 and base plate column mounting holes around center 33, post position limit net 2 and base plate 3 pass through to limit net column mounting holes 24 respectively and base plate column mounting holes 33 be fixedly mounted on vertical On post 132, thus forming central frame structure, frame fixed structure is more stable, and the requirement to center frame material reduces.
In above-described embodiment, as shown in Figure 10 or Figure 14, do not have due to outside center bracing strut 12 or central frame structure The obstruction of surrounding framework, the spacing hole 21 that post position limits net 2 edge can be placed during chromatographic column 200 not using open type design Need the whole top from chromatographic column frame 100 to pass through, only chromatographic column 200 directly need to be put into from the spacing hole 21 of opening, Pick and place using more convenient;Meanwhile, because the spacing hole of open type 21 is not full circle, chromatographic column 200 may drop out, therefore exist Spacing hole 21 opening both sides setting chromatographic column fix via hole 25, and arrange constraint chain 26 row constraint is entered to chromatographic column 200;About Bundle chain 26 is rope or the chain being fixed in the fixing via hole 25 of chromatographic column by wire rope handling or the turn of the screw.And it is located at center The spacing hole 21 that post position within framework limits on net 2 can be used for placing the chromatographic column 200 heavier, needs guarantee is safe, Or pick and place easier, lighter chromatographic column 200 for placing.
In above-described embodiment, as shown in figure 14, on post position restriction net 2, the edge of wide-aperture spacing hole 21 excavates further Go out the spacing hole 21 of the small-bore of multiple open types, so that a wide-aperture spacing hole 21 can place a thicker color Spectrum post 200 or place much thinner chromatographic columns 200 simultaneously and use, greatly improves the utilization in chromatographic column frame 100 space Rate.
In above-described embodiment, directly over base plate 3, about 1 centimeters fixedly mount the post position restriction net 2 of bottom, in base plate The post position fixedly mounting the top at about 1 meter directly over 3 limits net 2, and base plate 3 is used for holding all of chromatographic column 200, thus color Spectrum pylon 100 can be used for placing the chromatographic column 200 that length is 1 meter.
In above-described embodiment, for too short chromatographic column 200, held using base plate 3 just too low, be not suitable for desktop behaviour Make.Nets 2 can be limited topmost installing multiple identical post positions additional and the post position restriction net 2 of bottom between, exist simultaneously It is located at and install, on middle post position restriction net 2, the single-column supporting plate (not shown) that single chromatographic column 200 can be held up additional, for Place the identical or different shorter chromatographic column 200 of more thicknesses, also function to the effect of rigid support 1 simultaneously, and contribute to The decentralization of chromatographic column 200, increases the safety of chromatographic column frame 100;The position being located at middle each post position restriction net 2 is permissible Up-down adjustment, to place the chromatographic column 200 of different length as needed.
In above-described embodiment, the size that base plate 3 limits net 2 with post position is identical with specification, and base plate 3 and post position restriction net 2 can With using square, circular, rectangle or rounded square;It is of course also possible to adopt other shapes.
In above-described embodiment, support 1 is made using rustless steel;Post position limits net 2 and adopts relatively thin corrosion resistant plate, no Rust steel mesh or plastic plate cutting and;Base plate 3 is formed into using the larger corrosion resistant plate cutting of intensity.
In above-described embodiment, chromatographic column frame 100 bottom is additionally provided with universal wheel 4, facilitates chromatographic column frame 100 to exist as needed The indoor shift position of experiment.
It is exemplified below, limit with the diameter reasonable arrangement post position of different chromatographic columns 200 according to specific needs and open on net 2 If the quantity of spacing hole 21 of different pore size and putting position it is ensured that placing more chromatographic columns 200 in less area. For example, it is desired to place XK50/100 (maximum gauge 8.6cm, high 100cm about) and the XK16/100 (maximum gauge of Ge company 3.8cm, high 100cm about) chromatographic column, and with other shorter chromatographic columns of the length of diameter;The then spacing hole of XK50/100 Diameter is set to 9cm, and the spacing bore dia of XK16/100 is set to 4cm, and the chromatographic column of other sizes is placed and need to be arranged other diameters Spacing hole 21;9 centimetres of spacing hole 21 of diameter is evenly distributed on post position and limits on net 2, then in the spacing hole of 9 centimetres of diameter The spacing hole 21 of 4 centimetres of diameter is opened up between 21 hole.When using frame support 11, supporting use is a size of The square plate of 25.6cm*25.6cm manufactures post position and limits net 2, as shown in fig. 6, the post position of this example limits is provided with 4 on net 2 XK50/100 spacing hole 21 and 9 XK16/100 spacing holes 21.When using center bracing strut 12, supporting use is a size of The square plate of 25.6cm*25.6cm manufactures post position and limits net 2, and as shown in Figure 10, the post position of this example limits net 2 and is provided with 4 XK50/100 spacing hole 21 and 8 XK16/100 spacing holes 21, and employ the spacing hole 21 of half opening formula and design, facilitate color Taking-up put into by spectrum post 200, is fixed using rope or chain binding auxiliary simultaneously.When using center frame support 13, supporting Manufacture post position using the square plate of a size of 30cm*30cm and limit net 2, as shown in figure 14, the post position of this example limits net 2 and is provided with 9 XK50/100 spacing holes 21 or 32 XK16/100 spacing holes 21, every 1 XK50/100 spacing hole 21 also can place 3-4 XK16/100 chromatographic column 200, or the chromatographic column 200 that other diameters are less than 9cm can also be placed, and spacing hole 21 is used mostly The design of half opening formula, facilitates the chromatographic column 200 to put into taking-up, is fixed using rope or chain binding auxiliary simultaneously.
The various embodiments described above are merely to illustrate this utility model, and the structure of wherein each part, connected mode etc. are all permissible It is varied from, every equivalents carrying out on the basis of technical solutions of the utility model and improvement, all should not exclude Outside protection domain of the present utility model.

Claims (10)

1. a kind of chromatographic column frame is it is characterised in that this chromatographic column frame includes:
Support,
The post position offering multiple spacing holes limits net, and
Offer the base plate of multiple pipe fitting outlets;
Wherein, described spacing hole includes the aperture of plurality of specifications, and the aperture of described spacing hole is all higher than corresponding specification chromatographic column The maximum gauge at two ends;At least two pieces described post positions limit net, and vertically parallel interval is installed on the bracket, and respectively The position distribution that described post position limits online described spacing hole is consistent;Described base plate limits entoilage parallel to described post position It is fixed on described frame bottom, and be located at the lower section that the described post position of bottom limits net, the described pipeline pipe on described base plate The position distribution of part outlet is corresponding with the position distribution that described post position limits online described spacing hole.
2. chromatographic column frame as claimed in claim 1, it is characterised in that described support is frame support, is tied using space framework The described post position of structure fixation limits net and base plate;The described spacing hole that described post position limits net is sealing type, described spacing hole Edge has square groove.
3. it is characterised in that bracing strut centered on described support, described central shaft props up chromatographic column frame as claimed in claim 1 Frame includes central shaft base and is vertically arranged in the central shaft at described central shaft base center, and described post position limits in net and base plate The heart is fixedly mounted on described central shaft.
4. chromatographic column frame as claimed in claim 1 is it is characterised in that frame support, described Main subrack centered on described support Shape support includes central frame base and the center vertical around described central frame base is arranged on described central frame base On many root posts, described post position limits net and base plate is arranged on described column, forms central frame structure.
5. the chromatographic column frame as described in claim 3 or 4 is it is characterised in that the spacing hole that described post position limits network edge adopts Open type designs, and is respectively provided with the fixing via hole of chromatographic column and constraint chain, described constraint in the opening both sides of described spacing hole Chain is rope or the chain being fixed in the fixing via hole of described chromatographic column by wire rope handling or the turn of the screw.
6. chromatographic column frame as claimed in claim 5 is it is characterised in that described post position limits the side of wide-aperture spacing hole on the net Edge excavates out the spacing hole of the small-bore of multiple open types further, and the opening both sides of the spacing hole in described small-bore are respectively The fixing via hole of setting chromatographic column and constraint chain.
7. the chromatographic column frame as any one of Claims 1-4 it is characterised in that directly over described base plate 1 centimeters The described post position of fixed installation bottom limits net, the described post position of place's fixed installation the top 1 meter directly over described base plate Limit net.
8. chromatographic column frame as claimed in claim 7 is it is characterised in that limit net in the described post position with bottom topmost Between install multiple identical described post positions additional and limit nets, installing additional on the net and can hold up limiting positioned at middle described post position simultaneously The single-column supporting plate of single chromatographic column;The position being located at middle described post position restriction net being capable of up-down adjustment.
9. the chromatographic column frame as any one of Claims 1-4 is it is characterised in that described base plate is limited with described post position The size of net is identical with specification.
10. the chromatographic column frame as any one of Claims 1-4 is it is characterised in that the bottom of described chromatographic column frame also sets It is equipped with universal wheel.
CN201620940094.5U 2016-08-25 2016-08-25 Chromatogram pillar support Withdrawn - After Issue CN205965110U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201620940094.5U CN205965110U (en) 2016-08-25 2016-08-25 Chromatogram pillar support

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201620940094.5U CN205965110U (en) 2016-08-25 2016-08-25 Chromatogram pillar support

Publications (1)

Publication Number Publication Date
CN205965110U true CN205965110U (en) 2017-02-22

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201620940094.5U Withdrawn - After Issue CN205965110U (en) 2016-08-25 2016-08-25 Chromatogram pillar support

Country Status (1)

Country Link
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106345141A (en) * 2016-08-25 2017-01-25 中科生物制药股份有限公司 Chromatographic column rack

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106345141A (en) * 2016-08-25 2017-01-25 中科生物制药股份有限公司 Chromatographic column rack
CN106345141B (en) * 2016-08-25 2018-08-07 中科生物制药股份有限公司 A kind of chromatographic column frame

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Granted publication date: 20170222

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