CN106345141A - Chromatographic column rack - Google Patents
Chromatographic column rack Download PDFInfo
- Publication number
- CN106345141A CN106345141A CN201610720456.4A CN201610720456A CN106345141A CN 106345141 A CN106345141 A CN 106345141A CN 201610720456 A CN201610720456 A CN 201610720456A CN 106345141 A CN106345141 A CN 106345141A
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- China
- Prior art keywords
- chromatographic column
- net
- frame
- post position
- limits
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
Abstract
The invention relates to a chromatographic column rack. The chromatographic column rack comprises a bracket, column position limiting nets provided with multiple limiting pores, and a bottom plate provided with multiple pipe fitting outlets, wherein the limiting pores comprise pore diameters of multiple specifications, and the pore diameters of the limiting pores are all greater than the maximum diameters at two ends of a chromatographic column with a corresponding specification; at least two column position limiting nets are arranged on the bracket in parallel at intervals along the vertical direction, and the position distribution of the limiting pores in each column position limiting net is kept consistent; the bottom plate is fixed at the bottom of the bracket parallel to the column position limiting nets and positioned below the column position limiting net at the lowest end; and the position distribution of the pipe fitting outlets in the bottom plate corresponds to the position distribution of the limiting pores in the column position limiting nets. According to the chromatographic column rack disclosed by the invention, with the adoption of the column position limiting nets provided with the multiple limiting pores, multiple chromatographic columns of multiple specifications can be placed integrally, so that the storage space of the chromatographic columns is effectively saved, the bottom area of the chromatographic column rack is enlarged, and the problem of the stability does not need to be additionally considered.
Description
Technical field
The present invention relates to the auxiliary device in a kind of chromatogram purification technique, more particularly, to a kind of chromatographic column frame.
Background technology
Also known as chromatographic technique, operation principle is to be filled in the medium with certain attribute (referred to as fixing phase) to chromatographic technique
In cylindric straight tube (referred to as chromatographic column or chromatographic column, as shown in Figure 1), then using sample to be purified and various buffer solvent as stream
Dynamic mutually pass sequentially through fixing phase, according to the different attribute of fixing phase, sample to be purified can be according to size, electric charge, the physics such as hydrophobic
The difference of chemical property and separated, and flow out chromatographic columns, the solution of selection different phase by different sequencings
The less target substance of range of attributes just can be obtained, thus reaching the purpose of purification.Wherein, the medium of chromatographic column and wherein filling
Play a major role during isolating and purifying.
Chromatographic column needs to use auxiliary device chromatographic column frame when using, and the function of chromatographic column frame is exactly to make chromatographic column vertical
Place, and ensure the safety of chromatographic column during using and depositing.Large-scale chromatographic column volume mass is larger, typically all carries post
Frame, is readily transported movement；Laboratory room small-sized chromatographic column does not typically all have pylon, adopts the support of iron stand etc or is faced with clip
When fix；Medium chromatographic column may choose whether configure pylon.Regardless of chromatographic column, pylon is all very big in chromatographic column cost
Part, even above chromatographic column cost.Import pylon typically adopts solid high-quality steel, and therefore price is higher；Some domestic posts
Frame adopts light hollow steel, can only substantially keep the vertical state of chromatographic column, there is the potential safety hazard toppled over, and stationarity is owed
Good.
It is often necessary to purification is studied using the medium of different attribute in the research process of biological product and protein drug
Technique, meanwhile, different preparation batches is also required to the chromatographic column of different size, and such laboratory is accomplished by preparing many different rule
Lattice and the chromatographic column of filling different medium.But existing chromatographic column frame is both for the single chromatographic column of single specification and sets
Meter, general using vertically single stationary chromatographic post, such as Fig. 2 (a), (b) and Fig. 3 on the slightly larger base of the area of three feet or four feet
Shown in (a), (b).The leg of typically common single pylon can expand to floor space be not less than 25cm*25cm scope or with
On, to ensure the stability of chromatographic column frame, many root chromatogram columns all can take too many space using single pylon, and also needs to
Consider the stable problem that each chromatographic column is placed.
Content of the invention
For the problems referred to above, it is an object of the invention to provide a kind of chromatographic column frame, provide one for the many root chromatogram columns of many specifications
The deposit position of body, effectively saves parking space, and does not need to provide exceptional space for stable with base.
For achieving the above object, the present invention takes technical scheme below: a kind of chromatographic column frame is it is characterised in that this chromatograph
Pylon includes: support, and the post position offering multiple spacing holes limits net, and the base plate offering multiple pipe fitting outlets；Its
In, described spacing hole includes the aperture of plurality of specifications, and the aperture of described spacing hole is all higher than corresponding specification chromatographic column two ends
Maximum gauge；At least two pieces described post positions limit net, and vertically parallel interval is installed on the bracket, and each described post
The position distribution that position limits online described spacing hole is consistent；Described base plate limits entoilage parallel to described post position and is fixed on
Described frame bottom, and it is located at the lower section that the described post position of bottom limits net, the described pipe fitting outlet on described base plate
Position distribution and described post position limit online described spacing hole position distribution corresponding.
Described support is frame support, limits net and base plate using the described post position of space frame structure fixation；Described post position
The described spacing hole limiting net is sealing type, and the edge of described spacing hole has square groove.
Bracing strut centered on described support, described center bracing strut includes central shaft base and is vertically arranged in described center
The central shaft at axle base center, described post position limits net and base plate center is fixedly mounted on described central shaft.
Frame support centered on described support, described center frame support includes central frame base and around described center
The center vertical of frame base is arranged on the many root posts on described central frame base, and described post position limits net and base plate is installed
On described column, form central frame structure.
The spacing hole that described post position limits network edge adopts open type to design, and in the opening both sides of described spacing hole respectively
The fixing via hole of setting chromatographic column and constraint chain, described constraint chain is to be fixed on described chromatographic column admittedly by wire rope handling or the turn of the screw
Determine the rope in via hole or chain.
The edge that described post position limits wide-aperture spacing hole on the net excavates out the small-bore of multiple open types further
Spacing hole, and the opening both sides of the spacing hole in described small-bore are respectively provided with the fixing via hole of chromatographic column and constraint chain.
Directly over described base plate, 1 centimeters fixedly mount the described post position restriction net of bottom, just go up in described base plate
At 1 meter of side, the described post position of fixed installation the top limits net.
Limit nets topmost installing multiple identical described post positions additional and the described post position restriction net of bottom between,
Installing, positioned at middle described post position restriction, the single-column supporting plate that single chromatographic column can be held up on the net additional simultaneously；It is located at the described of centre
The position that post position limits net being capable of up-down adjustment.
Described base plate limits, with described post position, the size netted and specification is identical.
The bottom of described chromatographic column frame is additionally provided with universal wheel.
Due to taking above technical scheme, it has the advantage that a kind of chromatographic column frame of the 1, present invention to the present invention, passes through
Net is limited using the post position with multiple spacing holes, many root chromatogram column one of many specifications can be placed, effectively save chromatograph
The parking space of post, makes the bottom area of chromatographic column frame increase simultaneously, without the extra problem considering stability.2nd, the present invention
A kind of chromatographic column frame, according to the principle of " chopsticks cannot vertically be placed, and the chopsticks being bundled into just can easily be holded up ",
While effectively strengthening chromatographic column frame stability, the requirement to chromatographic column frame material can also be reduced, significantly reduce cost.3rd, originally
A kind of chromatographic column frame of invention, including the support of multiple fixed forms, can be according to actual stability and ease for use needs, choosing
Select specific chromatographic column frame structure, range of application is more extensive.
Brief description
Fig. 1 is the structural representation of chromatographic column；
Fig. 2 (a), (b) are the use state figure of the simple pylon of tradition respectively；
Fig. 3 (a), (b) are the use state figure of traditional standard pylon respectively；
Fig. 4 (a), (b) are that the present invention adopts use state figure during frame support respectively；
Fig. 5 is the structural representation of frame support of the present invention；
Fig. 6 is that the present invention adopts post position during frame support to limit the structural representation of net；
Fig. 7 is the structural representation that the present invention adopts base plate during frame support；
Fig. 8 (a), (b) are the use state figure that the present invention adopts during the bracing strut of center respectively；
Fig. 9 is the structural representation of center of the present invention bracing strut；
Figure 10 is the structural representation that when present invention adopts center bracing strut, post position limits net；
Figure 11 is the structural representation of base plate when the present invention adopts center bracing strut；
Figure 12 (a), (b) are the use state figure that the present invention adopts during the frame support of center respectively；
Figure 13 is the structural representation of center of the present invention frame support；
Figure 14 is the structural representation that when present invention adopts center frame support, post position limits net；
Figure 15 is the structural representation of base plate when the present invention adopts center frame support.
Specific embodiment
With reference to the accompanying drawings and examples the present invention is described in detail.
As shown in Fig. 4 (a), (b), Fig. 8 (a), (b) and Figure 12 (a), (b), a kind of chromatographic column frame 100 that the present invention provides,
It includes support 1, post position limits net 2 and base plate 3, according to stability and ease for use, selects the support 1 of different fixed forms.
Wherein, as shown in Fig. 6, Figure 10 and Figure 14, post position limit net 2 on offer multiple for placing chromatographic column 200
Spacing hole 21, spacing hole 21 includes multiple aperture, and the spacing hole 21 in aperture of different sizes is respectively used to place the different color of thickness
Spectrum post 200, the aperture of spacing hole 21 is slightly larger than the maximum gauge at chromatographic column 200 two ends, spacing to ensure that chromatographic column 200 can be put into
In hole 21 and be limited in the range of spacing hole 21, at least 2 pieces post positions limit net 2, and vertically parallel interval is fixed on
On frame 1, and the position distribution of the spacing hole 21 on each post position restriction net 2 should be consistent, to guarantee to be limited in chromatographic column 200
Vertical state；Post position limits the quantity of different pore size spacing hole 21 opening up on net 2 and putting position can specifically set as needed
Put, and the diameter reasonable arrangement according to different chromatographic columns 200, to guarantee to place more chromatographic columns 200 in less area.
As shown in Fig. 7, Figure 11 and Figure 15, base plate 3 offers multiple pipe fitting outlets 31, base plate 3 is parallel to post position
Limit net 2 ground and be fixed on support 1 bottom, and be located at the post position of bottom and limit below net 2, be used for bearing all chromatographic columns 200
Weight, the position distribution in the position distribution and post position restriction net 2 upper limit hole 21 of pipe fitting outlet 31 on base plate 3 is relative
Should.
In above-described embodiment, if Fig. 4 (a), (b) are with shown in Fig. 5, support 1 can be frame support 11, using space framework
Structure fixed column position limits net 2 and base plate 3, and structure is more stable, and material requirements is low；Due to the obstruction of frame support 11 surrounding,
Chromatographic column 200 need to be inserted from the top of chromatographic column frame 100 by chromatographic column frame 100 when using.As shown in fig. 6, propping up with shaped as frame
The spacing hole 21 that the post position that frame 11 uses cooperatively limits net 2 is sealing type, and the edge of spacing hole 21 has square groove 22, with
Just the interface of chromatographic column 200 side passes through.
In above-described embodiment, if Fig. 8 (a), (b) are with shown in Fig. 9～Figure 11, support 1 can also be center bracing strut 12, bag
The central shaft 122 including central shaft base 121 and being vertically arranged in central shaft base 121 center, post position restriction net 2 and base plate 3
Center opens up restricted net central shaft installing hole 23 and base plate center axis installing hole 32 respectively, and post position limits net 2 and base plate 3 difference
It is fixedly mounted on central shaft 122 by limiting net central shaft installing hole 23 and base plate center axis installing hole 32 center, due to adopting
Fixing with central shaft 122, the material requirements to central shaft 122 is slightly higher.
In above-described embodiment, if Figure 12 (a), (b) are with shown in Figure 13～Figure 15, support 1 can also be center frame support
13, including central frame base 131 with around on the centrally disposed frame base 131 of central frame base 131 center vertical
Many root posts 132, the edge certain distance away from central frame base 131 for many root posts 132, post position limits to be divided on net 2 and base plate 3
Do not offer the restriction net column mounting holes 24 corresponding with the position distribution of column 132 and base plate column mounting holes around center
33, post position limit net 2 and base plate 3 pass through to limit net column mounting holes 24 respectively and base plate column mounting holes 33 be fixedly mounted on vertical
On post 132, thus forming central frame structure, frame fixed structure is more stable, and the requirement to center frame material reduces.
In above-described embodiment, as shown in Figure 10 or Figure 14, do not have due to outside center bracing strut 12 or central frame structure
The obstruction of surrounding framework, the spacing hole 21 that post position limits net 2 edge can be placed during chromatographic column 200 not using open type design
Need the whole top from chromatographic column frame 100 to pass through, only chromatographic column 200 directly need to be put into from the spacing hole 21 of opening,
Pick and place using more convenient；Meanwhile, because the spacing hole of open type 21 is not full circle, chromatographic column 200 may drop out, therefore exist
Spacing hole 21 opening both sides setting chromatographic column fix via hole 25, and arrange constraint chain 26 row constraint is entered to chromatographic column 200；About
Bundle chain 26 is rope or the chain being fixed in the fixing via hole 25 of chromatographic column by wire rope handling or the turn of the screw.And it is located at center
The spacing hole 21 that post position within framework limits on net 2 can be used for placing the chromatographic column 200 heavier, needs guarantee is safe,
Or pick and place easier, lighter chromatographic column 200 for placing.
In above-described embodiment, as shown in figure 14, on post position restriction net 2, the edge of wide-aperture spacing hole 21 excavates further
Go out the spacing hole 21 of the small-bore of multiple open types, so that a wide-aperture spacing hole 21 can place a thicker color
Spectrum post 200 or place much thinner chromatographic columns 200 simultaneously and use, greatly improves the utilization in chromatographic column frame 100 space
Rate.
In above-described embodiment, directly over base plate 3, about 1 centimeters fixedly mount the post position restriction net 2 of bottom, in base plate
The post position fixedly mounting the top at about 1 meter directly over 3 limits net 2, and base plate 3 is used for holding all of chromatographic column 200, thus color
Spectrum pylon 100 can be used for placing the chromatographic column 200 that length is 1 meter.
In above-described embodiment, for too short chromatographic column 200, held using base plate 3 just too low, be not suitable for desktop behaviour
Make.Nets 2 can be limited topmost installing multiple identical post positions additional and the post position restriction net 2 of bottom between, exist simultaneously
It is located at and install, on middle post position restriction net 2, the single-column supporting plate (not shown) that single chromatographic column 200 can be held up additional, for
Place the identical or different shorter chromatographic column 200 of more thicknesses, also function to the effect of rigid support 1 simultaneously, and contribute to
The decentralization of chromatographic column 200, increases the safety of chromatographic column frame 100；The position being located at middle each post position restriction net 2 is permissible
Up-down adjustment, to place the chromatographic column 200 of different length as needed.
In above-described embodiment, base plate 3 is identical with the size of post position restriction net 2 and specification, and base plate 3 and post position restriction net 2 can
With using square, circular, rectangle or rounded square；It is of course also possible to adopt other shapes.
In above-described embodiment, support 1 is made using rustless steel；Post position limits net 2 and adopts relatively thin corrosion resistant plate, no
Rust steel mesh or plastic plate cutting and；Base plate 3 is formed into using the larger corrosion resistant plate cutting of intensity.
In above-described embodiment, chromatographic column frame 100 bottom is additionally provided with universal wheel 4, facilitates chromatographic column frame 100 to exist as needed
The indoor shift position of experiment.
It is exemplified below, limit with the diameter reasonable arrangement post position of different chromatographic columns 200 according to specific needs and open on net 2
If the quantity of spacing hole 21 of different pore size and putting position it is ensured that placing more chromatographic columns 200 in less area.
For example, it is desired to place xk50/100 (maximum gauge 8.6cm, high 100cm about) and the xk16/100 (maximum gauge of ge company
3.8cm, high 100cm about) chromatographic column, and with other shorter chromatographic columns of the length of diameter；The then spacing hole of xk50/100
Diameter is set to 9cm, and the spacing bore dia of xk16/100 is set to 4cm, and the chromatographic column of other sizes is placed and need to be arranged other diameters
Spacing hole 21；9 centimetres of spacing hole 21 of diameter is evenly distributed on post position and limits on net 2, then in the spacing hole of 9 centimetres of diameter
The spacing hole 21 of 4 centimetres of diameter is opened up between 21 hole.When using frame support 11, supporting use is a size of
The square plate of 25.6cm*25.6cm manufactures post position and limits net 2, as shown in fig. 6, the post position of this example limits is provided with 4 on net 2
Xk50/100 spacing hole 21 and 9 xk16/100 spacing holes 21.When using center bracing strut 12, supporting use is a size of
The square plate of 25.6cm*25.6cm manufactures post position and limits net 2, and as shown in Figure 10, the post position of this example limits net 2 and is provided with 4
Xk50/100 spacing hole 21 and 8 xk16/100 spacing holes 21, and employ the spacing hole 21 of half opening formula and design, facilitate color
Taking-up put into by spectrum post 200, is fixed using rope or chain binding auxiliary simultaneously.When using center frame support 13, supporting
Manufacture post position using the square plate of a size of 30cm*30cm and limit net 2, as shown in figure 14, the post position of this example limits net 2 and is provided with
9 xk50/100 spacing holes 21 or 32 xk16/100 spacing holes 21, every 1 xk50/100 spacing hole 21 also can place 3-4
Xk16/100 chromatographic column 200, or the chromatographic column 200 that other diameters are less than 9cm can also be placed, and spacing hole 21 is used mostly
The design of half opening formula, facilitates the chromatographic column 200 to put into taking-up, is fixed using rope or chain binding auxiliary simultaneously.
The various embodiments described above are merely to illustrate the present invention, and the structure of wherein each part, connected mode etc. are all can be
Change, every equivalents carrying out on the basis of technical solution of the present invention and improvement, all should not exclude the present invention's
Outside protection domain.
Claims (10)
1. a kind of chromatographic column frame is it is characterised in that this chromatographic column frame includes:
Support,
The post position offering multiple spacing holes limits net, and
Offer the base plate of multiple pipe fitting outlets；
Wherein, described spacing hole includes the aperture of plurality of specifications, and the aperture of described spacing hole is all higher than corresponding specification chromatographic column
The maximum gauge at two ends；At least two pieces described post positions limit net, and vertically parallel interval is installed on the bracket, and respectively
The position distribution that described post position limits online described spacing hole is consistent；Described base plate limits entoilage parallel to described post position
It is fixed on described frame bottom, and be located at the lower section that the described post position of bottom limits net, the described pipeline pipe on described base plate
The position distribution of part outlet is corresponding with the position distribution that described post position limits online described spacing hole.
2. as claimed in claim 1 a kind of chromatographic column frame it is characterised in that described support be frame support, using three-dimensional frame
The described post position of frame structure fixation limits net and base plate；The described spacing hole that described post position limits net is sealing type, described spacing
The edge in hole has square groove.
3. as claimed in claim 1 a kind of chromatographic column frame it is characterised in that bracing strut, described center centered on described support
Bracing strut includes central shaft base and is vertically arranged in the central shaft at described central shaft base center, and described post position limits net and bottom
Plate center is fixedly mounted on described central shaft.
4. as claimed in claim 1 a kind of chromatographic column frame it is characterised in that frame support centered on described support, described in
Heart frame support includes central frame base and the center vertical around described central frame base is arranged on described central frame
Many root posts on base, described post position limits net and base plate is arranged on described column, forms central frame structure.
5. a kind of chromatographic column frame as described in claim 3 or 4 is it is characterised in that described post position limits the spacing hole of network edge
Using open type design, and it is respectively provided with the fixing via hole of chromatographic column and constraint chain in the opening both sides of described spacing hole, described
Constraint chain is rope or the chain being fixed in the fixing via hole of described chromatographic column by wire rope handling or the turn of the screw.
6. as claimed in claim 5 a kind of chromatographic column frame it is characterised in that described post position limits wide-aperture spacing hole on the net
Edge excavate out further multiple open types small-bore spacing hole, and opening both sides of the spacing hole in described small-bore
It is respectively provided with the fixing via hole of chromatographic column and constraint chain.
7. a kind of chromatographic column frame as any one of Claims 1-4 is it is characterised in that 1 li directly over described base plate
The described post position of rice place fixed installation bottom limits net, 1 meter directly over described base plate at fixedly mount described in the top
Post position limits net.
8. as claimed in claim 7 a kind of chromatographic column frame it is characterised in that limiting with the described post position of bottom topmost
Install multiple identical described post positions between net additional and limit net, install energy on the net additional positioned at middle described post position restriction simultaneously
Hold up the single-column supporting plate of single chromatographic column；The position being located at middle described post position restriction net being capable of up-down adjustment.
9. a kind of chromatographic column frame as any one of Claims 1-4 is it is characterised in that described base plate and described post position
The size limiting net is identical with specification.
10. a kind of chromatographic column frame as any one of Claims 1-4 is it is characterised in that the bottom of described chromatographic column frame
It is additionally provided with universal wheel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610720456.4A CN106345141B (en) | 2016-08-25 | 2016-08-25 | A kind of chromatographic column frame |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610720456.4A CN106345141B (en) | 2016-08-25 | 2016-08-25 | A kind of chromatographic column frame |
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| Publication Number | Publication Date |
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| CN106345141A true CN106345141A (en) | 2017-01-25 |
| CN106345141B CN106345141B (en) | 2018-08-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610720456.4A Active CN106345141B (en) | 2016-08-25 | 2016-08-25 | A kind of chromatographic column frame |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109239245A (en) * | 2017-07-10 | 2019-01-18 | 中国科学院上海药物研究所 | A kind of chromatography column holder |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2122878A (en) * | 1982-07-02 | 1984-01-25 | Wright Scient Ltd | Racks for chromatography columns |
| CN201380083Y (en) * | 2009-03-26 | 2010-01-13 | 浙江荣泰科技企业有限公司 | Test tube rack for heating water bath |
| CN202427464U (en) * | 2011-11-14 | 2012-09-12 | 中国石油化工股份有限公司 | Porous open glass column support used in column chromatography analysis |
| CN203591822U (en) * | 2013-11-29 | 2014-05-14 | 姜兆兴 | Volumetric flask rack |
| CN205965110U (en) * | 2016-08-25 | 2017-02-22 | 中科生物制药股份有限公司 | Chromatogram pillar support |
-
2016
- 2016-08-25 CN CN201610720456.4A patent/CN106345141B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2122878A (en) * | 1982-07-02 | 1984-01-25 | Wright Scient Ltd | Racks for chromatography columns |
| CN201380083Y (en) * | 2009-03-26 | 2010-01-13 | 浙江荣泰科技企业有限公司 | Test tube rack for heating water bath |
| CN202427464U (en) * | 2011-11-14 | 2012-09-12 | 中国石油化工股份有限公司 | Porous open glass column support used in column chromatography analysis |
| CN203591822U (en) * | 2013-11-29 | 2014-05-14 | 姜兆兴 | Volumetric flask rack |
| CN205965110U (en) * | 2016-08-25 | 2017-02-22 | 中科生物制药股份有限公司 | Chromatogram pillar support |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109239245A (en) * | 2017-07-10 | 2019-01-18 | 中国科学院上海药物研究所 | A kind of chromatography column holder |
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| Publication number | Publication date |
|---|---|
| CN106345141B (en) | 2018-08-07 |
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Address after: No. 1155 Yingbin Road, Yanjiao Development Zone, Sanhe City, Langfang City, Hebei Province, 065200 Patentee after: Bohui Biopharmaceutical Co.,Ltd. Address before: No. 1155 Yingbin Road, Yanjiao Development Zone, Sanhe City, Langfang City, Hebei Province, 065201 Patentee before: ZHONGKE BIOPHARM CO.,LTD. |
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