CN205809401U - A kind of gravity type automatic threading scanning microscope - Google Patents

Abstract

nullThe utility model discloses a kind of gravity type automatic threading scanning microscope，The highest for solving microscope efficiency、Off-capacity、Function singleness、Baroque problem，Including microscope、Scanning feed mechanism、Enter sheet system、Driven film system，Enter sheet system and comprise section frame、Section box、Section frame feed arrangement，Before entering sheet，The section frame front end placing the section of multi-disc specimen is placed on the baffle plate of described section box，It is allowed at least one end higher than height during scanning mode，When entering sheet，Engaging of structure is driven with section frame by shell fragment，Then moved along section frame feeding opposite direction with section frame by section frame feed arrangement，Thus realize this section frame and fall under gravity on scanning feed mechanism，In tailing edge section frame feeding positive direction motor process，Through open front，And under tabletting effect, realize being accurately positioned of section frame、Fixing enter sheet function with complete section.

Description

A kind of gravity type automatic threading scanning microscope

Technical field

This utility model relates to automatic scanning microscope technical field, particularly relates to a kind of gravity type automatic threading scanning aobvious Micro mirror.

Background technology

Optical microscope explores the strong instrument of microcosmos as one, has been widely used in every medical treatment and has examined During disconnected and scientific experiments is studied, along with computer processing technology and the fast development of Digital image technology, it is achieved microscope is online Control, acquisition, persistence and the computer aided detection automatically of digital picture, it has also become the certainty of microscope automation development Trend, meanwhile, along with extensively carrying out of every medical treatment generaI investigation and deepening continuously of scientific research, along with digital virtual is cut into slices Extensive application, specimen quantity to be analyzed also increases considerably, as a example by Pasteur's cervix uteri specimen cut sections for microscopic examination, current separate unit Microscope needs the cervix uteri specimen section checked to reach several ten thousand every year on average, based on this, adds specimen and cut on micrometron The auto-feed function of sheet, it is achieved the automatic batch facility of the specimen section in the case of unmanned, it is achieved whole process is certainly Dynamicization is necessary, and this processes the ability of sample by being greatly improved scanning microscope and reduce microscope work expense.

A automatic feeding device for slide glass of microscope for examination is disclosed in the patent of Application No. 201120003599.6, should Device includes biological microscope, microscope slide disk, work mainboard, motor, Timing Belt drivewheel, Timing Belt, driven pulley, glass Sheet lifting unit；Wherein, microscope slide disk is uniformly provided with section groove, by rotating, the section in section groove is sent to scanning Position, is then lifted into section by slide elevator structure, it is achieved the acquisition to the parfocalization image cutting this specimen, after having observed, and glass Sheet elevating mechanism declines, and again section is put in section groove, and this device exists following problem: 1, mechanical arm is at object stage And directly transmission specimen section this self between Glass carrier box, owing to specimen section is to use glass material, it is easy to destroy mark This, this is can not be received in actual applications；2, this device is not carried out the specimen section X when image viewing, Y side To translation, be not carried out the scanning of image；3, section is placed in single circular array on microscope slide disk, causes the most empty Between waste, and cause yield single pass capacity very limited, being embodied as of this patent the most only achieves 16 sections Heap(ed) capacity；4, the motion of each of this device all uses single motor to drive, and causes structure, electrical equipment control the most complicated.

The document of numbered 1005-0930 (2005)-02-0185-09 discloses a kind of novel microscope slide certainly Dynamic Load System, this system is made up of Glass carrier box, special object stage and mechanical arm, this Glass carrier box is spaced apart specimen Section, it is possible to lower motion in the Z-axis direction, then realizes specimen by mechanical arm and cuts into slices between object stage and Glass carrier box Transfer, finally, on microscope, realize the automatic scanning to specimen section by object stage, there is following asking in this system Topic: 1, mechanical arm directly transmission specimen section this self between object stage and Glass carrier box, owing to specimen section is employing glass Glass material, it is easy to destroy specimen, this is can not be received in realizing application；2, empty in order to retain the operation of mechanical arm Between, each specimen is cut into slices in being spaced apart, and causes space waste, or causes yield single pass finite capacity, disclosed money Material only achieves the heap(ed) capacity of 25 sections；3, move up and down to sheet owing to the scanning of each section has been required for carrying glass box Position, mechanical arm realize into sheet, stage movement to scan position, scanning, stage movement to moving back sheet position, mechanical arm realization Move back the motion that sheet etc. cannot be parallel, cause the time to waste, inefficient；4, due to mechanical arm, the motion of glass box, stage movement are carried All using single motor to drive, cause electrical equipment, frame for movement the most complicated, thus cause cost the highest, reliability is the most significantly Decline.

Application No. 201120466334.X, 201420402943.2,201010188659.6, 201410347521.4, the patent of 200780008213.7,200510043744.2 all discloses microscope specimen section Automatic threading mechanism, but ultimate principle all with the similar class of document 1005-0930 (2005)-02-0185-09, be use plane Moving stage device, the load that moves up and down glass box, specimen section transfer device reach automatic threading effect, simply concrete structure Slightly different, therefore the most all there is above-mentioned weak point.

Patent in Application No. 201110071788.1 discloses a microscope specimen section auto-feeder, should Device comprises slide pusher, fluctuating plate device and moves horizontally clamping device, and specimen slice spacings is placed on cassette, Then specimen section transfer between object stage and Glass carrier box is realized by slide pusher, fluctuating plate device, finally, The automatic scanning cut into slices specimen by moving horizontally clamping device to realize on object stage, there is following asking in this system Topic: 1, mechanical arm directly transmission specimen section this self between object stage and Glass carrier box, owing to specimen section is employing glass Glass material, it is easy to destroying specimen, this is can not be received in actual applications；2, in order to retain the behaviour of slide pusher Making space, each specimen is cut into slices in being spaced apart, and causes space waste, or causes yield single pass finite capacity；3, by Scanning in each section is required for into sheet, moves back the motion that sheet etc. cannot be parallel, causes the time to waste, inefficient；4, by All use single motor to drive in slide pusher, fluctuating plate device, cause electrical equipment, frame for movement the most complicated, thus Causing cost the highest, reliability also declines to a great extent.

Patent in Application No. 201180048354.8 proposes a kind of microscope automatic scan slice system, at this Microscope automatic scan slice system employs a kind of section frame, and multi-disc section is fixed on section frame, then multiple Section frame is parallel to be overlayed in section box and scanning track, finally, uses a carbine that the section frame in section cassette bottom portion is drawn Go out, be allowed to travel forward hence into scanning area along scanning track, be mutually perpendicular to scanning base two by scanning track Horizontal movement realize microscopical scan function, this system can preferably solve the problems of aforementioned schemes, but still There is following problem: 1, owing to section frame overlays in scanning track, when there is overlapping region, frame of cutting into slices in upper end Action of gravity under, cause the longest region all to there is frictional force very big, and the problem of stress change, cause in this section of district Product Precision insecure problem during the scanning of territory, if not scanning in this region and can cause product space very big, reduces efficiency Problem；2, owing to being to use shell fragment hook, the one-way movement of section frame can only be realized, so be first modeled scanning again at needs Or during with function that the direction is particles direction, this system all can not realize, and greatly limit the range of product； 3, owing to being that section frame is placed in scanning track, the inapplicable conventional microscope for band object stage of this scheme is caused, can only For with in the microscope of the program, it is impossible to use this scheme to change conventional microscope, seriously limit the use of this scheme Scope.

Utility model content

In order to solve above-mentioned technical problem, this utility model provides a kind of gravity type automatic threading scanning microscope.This The surface sweeping microscope of utility model can solve the problem that inefficient in existing scanning microscope, off-capacity, reliability are the most high all Many problems.

Concrete technical scheme of the present utility model is: a kind of gravity type automatic threading scanning microscope, it include microscope, Scanning feed mechanism, enter sheet system, driven film system, described enters sheet system including at least section frame, section box, section frame feeding Device.

Described section frame front has multiple section groove, side to have driving structure, and described each section groove exists longitudinal and transverse To elastic lever, the lateral thrust that produced by elastic lever, down thrust make the section of each specimen can be fixed on each to cut In film trap, follow-up enter sheet, scanning time all cut into slices with section frame and specimen and operate for entirety, be the most also achieved that multiple Feeding while specimen section, decreased into the sheet time, simultaneously as all motion stress in whole scanning, motor process All act on section frame, it is achieved the protection to section.

Described section frame feed arrangement is fixedly mounted on scanning feed mechanism, and it is including at least one and drives structure Suitable shell fragment, directly uses the motion of scanning feed mechanism as the driving source entering sheet, say, that a mechanism With realize scanning motion can also realize into sheet move, enormously simplify structure.

Described section box is also including at least baffle plate, open front, an after-opening, and described open front, after-opening are the most only Can allow that the section frame described in monolithic frees in and out along section frame direction of feed, described baffle plate is in the position, upper end of open front Put；So, described section box stacking can place multiple described section frame, and before entering sheet, described section frame front end is placed On described baffle plate, it is allowed at least one end higher than height during scanning mode, when entering sheet, described shell fragment and described section box In the section frame of the bottom drive structure engagement, only allow that due to after-opening single section frame passes freely through, thus also only One section frame tangential section frame feeding opposite direction motion of the energy bottom, when this move distance is more than the width of described plate washer, This section frame is no longer supported by baffle plate, thus falls in the section frame position location of scanning feed mechanism under gravity, Rear cutout horse is with along scanning feed mechanism edge section frame feeding positive direction motor process, through open front, and under tabletting effect Realize section being accurately positioned of frame, fixing, thus complete into sheet function, and, due to the section frame in described section box all Higher than section frame during scanning mode, also it is scanned for feed mechanism and this section frame can be driven freely to retreat.

Under said structure scheme, this gravity type automatic threading scanning microscope to enter sheet step as follows:

The first step: scanning microscope moves to scan initial position；

Second step: specimen section fixed placement in the section frame of rigid material；

3rd step: multiple section rack-layer stacked are placed in section box, any one section frame at least one end now Scanning mode position higher than section frame；

4th step: scanning feed mechanism band spring plate enters into into sheet position, and makes the driving structure of shell fragment and section frame Machine engages；

5th step: under the effect of engagement force, sweep mechanism is further driven to the section frame of the bottom along feeding opposite direction Move across after-opening, until section frame front end departs from baffle plate；

6th step: depart from the section frame of plate washer under gravity, falls on the locating surface of scanning feed mechanism；

7th step: scanning feed mechanism moves along feeding positive direction with the section frame fallen and passes open front, and During this, under the effect of tabletting, section frame is accurately positioned；

8th step: scanning feed mechanism continues to drive section frame to scan position, starts scanning.

Gravity type automatic threading structure provided by the utility model and enter sheet method, enters compared to existing technology, also has There is a following advantage:

1, it i.e. may be used for the scanning microscope of object stage formula, it is also possible to for guide tracked scanning microscope；

2, enter sheet scanning time specimen section transfer, motion all with cut levy frame motion, all stress all act on section Horse, can protect section preparation, it is to avoid damaged due to the effect of external force；

3, once enter sheet process just to cut into slices with feeding multi-disc, efficiency is greatly improved；

4, the motion using scanning feed mechanism i.e. realizes scanning motion, also utilizes this motion to realize the feeding of section frame, Structure significantly simplifies；

5, having only to the width of tangential section frame feeding opposite direction motion baffle plate, drop downwards section frame thickness and baffle plate Thickness, move distance is the least, and the follow-up section frame location set time is scanning feed motion the most simultaneously, therefore individually enters Sheet movement travel is the least, and the feeding time of corresponding each section frame is the most little；

6, put owing to section frame stacks in section box middle level, frame of cutting into slices utilizes gravity feeding, so, come from stress and space Say, be all easily achieved Large Copacity, it is easy to just can exceed that 100；

7, simplifying due to structure, and all section rack-layers stack and put, the movement travel needed for section frame feeding is the least, institute Compact with total；

8, drive mechanism drives the section frame can be with back and forth movement, it is achieved multiple merits such as modeling, scan, local essence the most again is swept Energy；

9, in scanning process, whole driving frame stress is constant, improves Product Precision and reliability.

Accompanying drawing explanation

Fig. 1 is to realize overall construction drawing of the present utility model in guide tracked scanning microscope；

Fig. 2 is to realize overall construction drawing of the present utility model in the desk-top scanning microscope of loading；

Fig. 3 is the plastic material formula section frame structural map of convex drive mechanism of the present utility model；

Fig. 4 is the plastic material formula section frame structural map of spill drive mechanism of the present utility model；

Fig. 5 is the metal material formula section frame structural map of spill drive mechanism of the present utility model；

Fig. 6 is the structural map of monoblock type of the present utility model section box；

Fig. 7 is that automatic slice feeder for microscope scans initial position operating diagram；

Fig. 8 is that automatic slice feeder for microscope starts into sheet position operating diagram；

Fig. 9 is that automatic slice feeder for microscope enters sheet and completes position operating diagram；

Figure 10 is automatic slice feeder for microscope scanning mode operating diagram.

Detailed description of the invention

Below in conjunction with embodiment, the utility model will be further described.

Embodiment 1

Fig. 1 is to realize overall construction drawing of the present utility model, the gravity in the present embodiment in guide tracked scanning microscope Formula automatic threading scanning microscope, its mainly by microscope 11, driven film system 12, enter sheet system 13 and scanning feed mechanism 14 structure Become.Enter sheet system 13 to be mainly made up of section frame 3, section box 6a and section frame feed arrangement 131.Section frame feed arrangement 131 It is installed with a shell fragment 1311 suitable with driving structure.

Gravity type automatic threading scanning microscope in the present embodiment enters fixed placement of first specimen being cut into slices before sheet works In the section groove of section frame 3.If Fig. 3 is the plastic material formula section frame structural map of convex drive mechanism of the present utility model, Its front is provided with multiple section groove 31, is provided with vertical, horizontal elastic lever 311 in section groove 31, and side is provided with convex and drives structure 32。

Next combine the overall construction drawing of the present embodiment and operating diagram to tell about lower the present embodiment concrete enter sheet Step:

Fig. 7 is that automatic slice feeder for microscope scans initial position operating diagram.First will section frame feed arrangement 131 Move to scan initial position, the more multiple section framves 3 installing specimen section are placed in section box stackedly.Described Section box 6a is split-type structural form, and it is including at least having open front 6a1, a baffle plate 6a2 and after-opening 6a3.Open front 6a1 and after-opening 6a3 is only capable of allowing that monolithic section frame 3 frees in and out along section frame 3 direction of feed；Baffle plate 6a2 opens before being positioned at The upper end position of mouth 6a1；The front position of section frame 3 is placed on baffle plate 6a2, is allowed at least one end higher than during scanning mode Highly.Open the stepper motor driver 143 on scanning feed mechanism 14, make the bullet being fixed on section frame feed arrangement 131 Sheet 1311 starts to move to feeding opposite direction along with section frame feed arrangement 131.

Fig. 8 is that automatic slice feeder for microscope starts into sheet position operating diagram.When being fixed on section frame feeding dress When putting the position that the shell fragment 1311 on 131 moves in operating diagram to feeding opposite direction, shell fragment 1311 is cut with the bottom The driving structure 32 of horse 3 engages, and owing to after-opening 6a3 only allows that single section frame 3 passes freely through, thus can only drive the end One section frame 3 tangential section frame 3 feeding opposite direction motion of layer.

Fig. 9 is that automatic slice feeder for microscope enters sheet and completes position operating diagram.When shell fragment 1311 and the bottom After continuing to move toward feeding opposite direction after driving structure 32 engagement of section frame 3, gear can be left in the front end of the section frame 3 of the bottom Plate 6a2, at this moment the section frame 3 of the bottom is no longer supported by baffle plate 6a2, thus falls under gravity at scanning feed mechanism On the section frame position location 141 of 14；Arrive at banking stop 132 when shell fragment 1311 continues to drive toward the motion of feeding opposite direction, After the lower end of shell fragment 1311 limited switch 133 sensing simultaneously, section frame feed arrangement 131 stops moving to feeding opposite direction, Then start to move to feeding positive direction.

Figure 10 is automatic slice feeder for microscope scanning mode operating diagram.Shell fragment 1311 and the driving of section frame 3 Structure 32 engagement continues to move to feeding positive direction.When the section frame 3 of the bottom leaves the open front 6a1 of section box 6a, after Under the influence of gravity, the section frame 3 dropping to lowermost layer starts the position into sheet to continuous section frame 3.Section when the bottom After frame 3 leaves the open front 6a1 of section box 6a, under tabletting 142 effect of scanning feed mechanism 14, realize the accurate of section frame 3 Positioning, fix, the scanning area finally entering microscope 11 is scanned work.

Be above the present embodiment specifically enters sheet step, during whole automatic threading, due in section box 6a Section frame 3 is all higher than the section frame 3 during scanning mode so that scanning feed mechanism 14 can drive section frame during scanning mode 3 freely retreat.

Embodiment 2

As shown in Figure 4, plastic material formula section its front of frame that section frame 3 is spill drive mechanism in embodiment 2 sets Having multiple section groove 41, be provided with vertical, horizontal elastic lever 411 in section groove 41, side is provided with spill and drives structure 42.

As shown in Figure 6, the box typed structure form that described section box 6 is integrated, it also including at least have open front 61, One baffle plate 62 and after-opening 63, section frame can also be carried out spacing by its housing when feeding opposite direction is moved.The present embodiment is adopted Be the section box of split-type structural form.

Embodiment 3

As it is shown in figure 5, the metal material formula section frame that section frame 3 is spill drive mechanism of the present embodiment, its front sets Having multiple section groove 51, shell fragment 511 is fixed in section groove 51, and side is provided with spill and drives structure 52.

Embodiment 4

Fig. 2 is to realize overall construction drawing of the present utility model in the desk-top scanning microscope of loading.Weight in the present embodiment Power formula automatic threading scanning microscope, its mainly by pedestal 21, enter sheet system 22, microscope 23 and driven film system 24 and constitute.Enter Sheet system 22 is mainly made up of section frame 3, section box 6, section frame feed arrangement 221 and limit switch 222.Section frame feeding dress Put 221 and be all installed with a shell fragment suitable with driving structure.

In conjunction with Fig. 1 and Fig. 2, the present embodiment and embodiment 1 enter sheet mode with to enter sheet step basically identical, difference exists In:

1, the microscope 23 used is the desk-top scanning microscope of loading.

2, section box 6 uses the box typed structure form of one.

3, need a pedestal 21, make to be fixed on pedestal 21 into sheet system 22, microscope 23 and driven film system 24.

4, there are locating piece 231 and tabletting 232 on the object stage of microscope 23, to ensure that section frame 3 enters energy after object stage Carry out being accurately positioned, fixing.

Raw materials used, equipment in this utility model, unless otherwise noted, is the conventional raw material of this area, equipment；This reality With novel middle method therefor, unless otherwise noted, it is the conventional method of this area.

The above, be only preferred embodiment of the present utility model, not impose any restrictions this utility model, every Any simple modification, change and the equivalent transformation made above example according to this utility model technical spirit, all still falls within The protection domain of technical solutions of the utility model.

Claims (10)

1. a gravity type automatic threading scanning microscope, including microscope, scans feed mechanism, enters sheet system, driven film system； It is characterized in that:

Described enter sheet system including at least section frame, section box, section frame feed arrangement；Described section is set up in described section box In, described section box is located at above described section frame feed arrangement；Described section frame feed arrangement is fixed on described scanning feeding In mechanism；The front of described section frame is provided with multiple section groove, there are driving structure, described each section groove in the side of section frame At least provided with an elastic lever；At least provided with a shell fragment suitable with driving structure on described section frame；Described section Box includes at least baffle plate, open front, an after-opening, and described open front is positioned on section box near microscopical side, described After-opening is positioned at the most microscopical side on section box；Described open front, after-opening are all only capable of the section allowed described in monolithic Frame frees in and out along section frame direction of feed, and described baffle plate is in the upper end position of open front；Described section frame front end is positioned over On described baffle plate, and at least one end of section frame is higher than height during scanning mode.

A kind of gravity type automatic threading scanning microscope the most according to claim 1, it is characterised in that: described section frame is Convex drives the section frame of structure, and its front is provided with multiple section groove, is provided with vertical, horizontal elastic lever in section groove, and side sets Convex is had to drive structure.

A kind of gravity type automatic threading scanning microscope the most according to claim 1, it is characterised in that: described section frame is The section frame of spill drive mechanism, its front is provided with multiple section groove, is provided with vertical, horizontal elastic lever in section groove, and side sets Spill is had to drive structure.

A kind of gravity type automatic threading scanning microscope the most according to claim 1, it is characterised in that: described section box is Box typed structure integrally or the split-type structural being made up of multiple independent parts.

A kind of gravity type automatic threading scanning microscope the most according to claim 4, it is characterised in that: described section box Open front, after-opening are in sustained height.

A kind of gravity type automatic threading scanning microscope the most according to claim 4, it is characterised in that: described section box Open front, after-opening are in differing heights.

7. according to a kind of gravity type automatic threading scanning microscope described in claim 5 or 6, it is characterised in that: open after described Mouth and scanning mode are in same level.

8. according to a kind of gravity type automatic threading scanning microscope described in claim 1 or 2 or 3, it is characterised in that cut described in: The driving structure of horse uses trapezoidal shape, square configuration or semicircular in shape.

A kind of gravity type automatic threading scanning microscope the most according to claim 2, it is characterised in that: described shell fragment uses U-shaped opening shape.

A kind of gravity type automatic threading scanning microscope the most according to claim 3, it is characterised in that: described shell fragment is adopted Use solid squares.