CN205649728U - Blood vessel drug treatment device based on piezoelectricity drive - Google Patents

Blood vessel drug treatment device based on piezoelectricity drive Download PDF

Info

Publication number
CN205649728U
CN205649728U CN201620198345.7U CN201620198345U CN205649728U CN 205649728 U CN205649728 U CN 205649728U CN 201620198345 U CN201620198345 U CN 201620198345U CN 205649728 U CN205649728 U CN 205649728U
Authority
CN
China
Prior art keywords
titanium alloy
bolt
alloy substrate
hole
piezoelectric ceramic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn - After Issue
Application number
CN201620198345.7U
Other languages
Chinese (zh)
Inventor
彭瀚旻
朱攀丞
陈致均
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing University of Aeronautics and Astronautics
Original Assignee
Nanjing University of Aeronautics and Astronautics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing University of Aeronautics and Astronautics filed Critical Nanjing University of Aeronautics and Astronautics
Priority to CN201620198345.7U priority Critical patent/CN205649728U/en
Application granted granted Critical
Publication of CN205649728U publication Critical patent/CN205649728U/en
Withdrawn - After Issue legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Surgical Instruments (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Apparatuses For Generation Of Mechanical Vibrations (AREA)

Abstract

The utility model discloses a blood vessel drug treatment device based on piezoelectricity drive utilizes double -basis body structure advantage, realizes the straight line and the rotary motion of device, advances line location and doses lesion tissues in the blood vessel. Utilize the ultrasonic atomization liquid medicine of piezoceramics production to realize the release of liquid medicine. Utilize the hyperacoustic therapeutic action of piezoceramics oscillation generation, when detecting lesion tissues, dose in real time and accelerate its absorption rate lesion tissues, improve the absorption efficiency, reach the purpose of curing the disease with the medicine volume of minimum. This vascular drug treatment device can reduce the side effect that unnecessary medicine produced in the traditional healing method by a wide margin, just cures fast lesion tissues when detecting lesion tissues, reaches inspection convenience, no wound, no wire, nothing misery, has cross infection, reduces the purpose of dose and high cure rate.

Description

Vascular drug delivery therapy equipment based on Piezoelectric Driving
Technical field:
This utility model relates to a kind of vascular drug delivery therapy equipment based on Piezoelectric Driving, and it belongs to ultrasound field, MEMS Field, ultrasound medicine, technical field of piezoelectricity.
Background technology:
Vascular drug delivery is a kind of administering mode that can immediately come into force, and is widely used clinically.But some medicine intravascular Input, can cause extravasation tissue injury in various degree, and the lighter causes pain uncomfortable, and severe one causes dysfunction, very To amputation and threat to life.The occur character with extravasation property medicine and the individual patients situation of exsomose injury have pass closely System.Other is such as infusion amount, input speed, perfusion persistent period, pressure, drug level, tissue toxicity, tissue pressure etc. This is also had an impact.Particularly intensive care patient, children's and old people, diabetes patient and vascular disease.One Denier medicinal liquid exosmoses, and is more easy to cause damage.And ultrasonic importing medicine-feeding technology is the emerging therapeutic administration that closely grows up during the last ten years Technology, by the physical action of low frequency ultrasound, makes horny layer inner cell wall or biological corridor expand, makes macromole medicine Thing or medicinal liquid gradually can be input in the middle of pathological tissues from Ink vessel transfusing.This technology can make some originally can not absorb Medicine be absorbed by tissue, originally can just be rapidly absorbed by absorbed medicine, therefore it can improve biological tissue's medicine Permeability, expands the uniformity of drug distribution, thus improves the treatment rate of medicine.And the structure utilizing ultrasound electric machine is excellent Gesture, can be accurately positioned pathological tissues at Ink vessel transfusing and be administered.
Utility model content:
Technical problem to be solved in the utility model is for above-mentioned the deficiencies in the prior art, and provides a kind of based on piezoelectricity The vascular drug delivery therapy equipment driven.
This utility model adopts the following technical scheme that a kind of vascular drug delivery therapy equipment based on Piezoelectric Driving, including first Titanium alloy substrate, the first piezoelectric ceramic piece being installed on the first titanium alloy substrate, the second titanium alloy substrate, it is installed on The second piezoelectric ceramic piece on two titanium alloy substrates, bolt, radiation under, rotating disk, the 3rd piezoelectric ceramic piece, the 4th piezoelectricity Potsherd, lesion detection device, medicine storage device and nozzle containing photographic head, on described first titanium alloy substrate It is formed through the first hole of the first left and right side of titanium alloy substrate, the second titanium alloy substrate is also formed through second Second hole of the left and right side of titanium alloy substrate, described bolt right-to-left is arranged in the second hole, the first hole successively, spiral shell The left-end point of bolt is positioned in the first titanium alloy substrate, the right end of bolt extend beyond the second titanium alloy substrate right edge it Outward, the bolt partial outer face being positioned in the first hole is smooth, and the inner surface in the first hole is also smooth, bolt appearance Face is matched in clearance with the inner surface in the first hole, and the bolt partial outer face being positioned in the second hole is screw-shaped, the second hole Inner surface be smooth, the right end thread of described bolt is connected to the lateral edges of rotating disk, described radiation under be installed on turn The cental axial position of dish, described radiation under is positioned at the position below rotating disk and is provided with a cavity, described 3rd piezoelectric ceramic piece Being installed on the radiation under between rotating disk and cavity, described 4th piezoelectric ceramic piece is installed on the inside bottom surface of cavity, Described nozzle and lesion detection device lay respectively at the left and right sides of radiation under lower surface, and described medicine storage device is positioned at Between four piezoelectric ceramic pieces and nozzle.
This utility model also adopts the following technical scheme that the work side of a kind of vascular drug delivery therapy equipment based on Piezoelectric Driving Method, comprises the steps:
Step 1. vascular drug delivery based on Piezoelectric Driving therapy equipment enters person under inspection's Ink vessel transfusing, flows with blood, motion Near pathological tissues, telling external operation personnel by the photographic head in lesion detection device, device is close to affected part;
Step 2. second piezoelectric ceramic piece, under the effect of sine and cosine voltage, makes the second titanium alloy substrate produce relative to it The twist motion of axis, the second titanium alloy-based internal bolt part has screw thread, the twist motion of the second titanium alloy substrate, Making bolt create linear motion, bolt is connected with rotating disk, makes whole rotating disk move along a straight line, so that nozzle pair Quasi-lesion, then be discharged into after medicinal atomized in medicine storage device through nozzle by the vibration of the 4th piezoelectric ceramic piece Pathological tissues surface;
Step 3. first piezoelectric ceramic piece, under the effect of sine and cosine voltage, makes the first titanium alloy substrate produce relative to it The twist motion of axis, the first titanium alloy-based internal bolt part does not has screw thread, and bolt is by rubbing between surface both Wiping power is driven, and bolt is rotated, and bolt is connected with rotating disk, makes whole rotating disk be rotated, from And make radiation under rotate 180 °, then produce ultrasound wave by the vibration of the 3rd piezoelectric ceramic piece, pathological tissues is carried out reality Time deep treatment, accelerate lesion region drug absorption, reach rapid healing purpose, repeating as above step, making spoke Rhizoma Belamcandae rotates again 180 °;
Step 4. lesion detection device continues to detect the Cure of pathological tissues in real time, thus further controls Pharmacy liquid measure, is finally reached and detects the purpose integrated with treatment, when completing to one after the process of lesion, for it Its lesion, repeat the above steps.
This utility model has the advantages that this utility model utilizes Double substrate micro structural advantage, it is achieved the straight line of device With rotary motion, pathological tissues positioned at Ink vessel transfusing and is administered.Utilize the ultrasonic fog chemical medicine that piezoelectric ceramics produces Liquid, thus realize the release of medicinal liquid.Piezoelectric ceramic vibration is utilized to produce the therapeutical effect of ultrasound wave, at detection pathological tissues While, pathological tissues is administered and accelerates its absorption rate in real time, improves absorption efficiency, reach with minimum medicine The purpose of thing amount cure diseases.This vascular drug delivery therapy equipment can significantly reduce extra medicinal in traditional therapy and produce Side effect, detection pathological tissues while just pathological tissues is carried out rapid healing, reach inspection convenience, hurtless measure, Without wire, no pain, without cross infection, reduce dose and the purpose of high curative rate.
Accompanying drawing illustrates:
Fig. 1 is structural representation of the present utility model.
Fig. 2 is the operating diagram of this utility model titanium alloy substrate.
Wherein:
1-the first titanium alloy substrate;2-the first piezoelectric ceramic piece;3-the second titanium alloy substrate;4-the second piezoelectric ceramic piece; 5-bolt;6-radiation under;7-rotating disk;8-the 3rd piezoelectric ceramic piece;9-the 4th piezoelectric ceramic piece;10-lesion detection device (containing photographic head);11-medicine storage device;12-nozzle.
Detailed description of the invention:
Refer to shown in Fig. 1 and Fig. 2, this utility model vascular drug delivery based on Piezoelectric Driving therapy equipment includes the first titanium Alloy substrate 1, first piezoelectric ceramic piece the 2, second titanium alloy substrate 3 being installed on the first titanium alloy substrate 1, installation The second piezoelectric ceramic piece 4 on the second titanium alloy substrate 3, bolt 5, radiation under 6, rotating disk the 7, the 3rd piezoelectric ceramics Sheet the 8, the 4th piezoelectric ceramic piece 9, lesion detection device 10, medicine storage device 11 and nozzle containing photographic head 12.First hole (sign) of the first left and right side of titanium alloy substrate 1 it is formed through on first titanium alloy substrate 1, Also second hole (sign) of the second left and right side of titanium alloy substrate 3 it is formed through on second titanium alloy substrate 3, During wherein bolt 5 right-to-left is arranged in the second hole, the first hole successively, wherein the left-end point of bolt 5 is positioned at the first titanium conjunction In auri body 1, the right end of bolt 5 extends beyond outside the right edge of the second titanium alloy substrate 3.Wherein it is positioned at first Bolt partial outer face in hole is smooth, and the inner surface in the first hole is also smooth, bolt outer surface and the first hole Inner surface is matched in clearance, and bolt 5 and the first titanium alloy substrate 1 are by between bolt outer surface and the first internal surface of hole Frictional force is driven.The bolt partial outer face being positioned in the second hole is screw-shaped, and the inner surface in the second hole is smooth , bolt 5 and the second titanium alloy substrate 3 are to be connected with each other by the screw thread between bolt outer surface and the second internal surface of hole. The right end thread of bolt 5 is connected to the lateral edges of rotating disk 7, and radiation under 6 is installed on the cental axial position of rotating disk 7.Spoke Being positioned at the position below rotating disk 7 on Rhizoma Belamcandae 6 and be provided with a cavity 13, the 3rd piezoelectric ceramic piece 8 is installed on rotating disk 7 and cavity On radiation under 6 between 13, the 4th piezoelectric ceramic piece 9 is installed on the inside bottom surface of cavity 13, nozzle 12 and disease Becoming detection device 10 and lay respectively at the left and right sides of radiation under 6 lower surface, medicine storage device 11 is positioned at the 4th piezoelectricity pottery Between ceramics 9 and nozzle 12.
The operation principle of this utility model vascular drug delivery based on Piezoelectric Driving therapy equipment is as follows: the first piezoelectric ceramic piece 2, Second piezoelectric ceramic piece 4, respectively under the effect of sine and cosine voltage, makes the first titanium alloy substrate 1 and the second titanium alloy substrate 3 produce the twist motion relative to its axis, and the bolt part being wherein arranged in the first titanium alloy substrate 1 does not has screw thread, Bolt is rotated, and the bolt part being arranged in the second titanium alloy substrate 3 has screw thread, bolt to move along a straight line. Bolt 5 is connected with rotating disk 7 again, so that whole rotating disk 7 completes straight line under the effect of sine and cosine voltage or rotates through Journey.Lesion detection device 10 monitoring in real time and pathological tissues carried out cause of disease detection for device, it is also possible to detection is controlled Liao Hou biological tissue Cure.By the vibration of the 4th piezoelectric ceramic piece 9 by the medicine mist in medicine storage device 11 It is discharged into pathological tissues surface through nozzle 12 after change, produces ultrasound wave by the vibration of the 3rd piezoelectric ceramic piece 8, to disease Become tissue and carry out real-time deep treatment, accelerate the drug absorption of lesion region, reach rapid healing purpose.
The work process of this utility model vascular drug delivery based on Piezoelectric Driving therapy equipment is as follows:
Step 1. vascular drug delivery based on Piezoelectric Driving therapy equipment enters person under inspection's Ink vessel transfusing, and it flows with blood, fortune Moving near pathological tissues, tell external operation personnel by the photographic head in lesion detection device 10, device is the most close Affected part.
Step 2. second piezoelectric ceramic piece 4, under the effect of sine and cosine voltage, makes the second titanium alloy substrate 3 produce relatively Bolt part in the twist motion of its axis, the second titanium alloy substrate 3 has screw thread, so the second titanium alloy substrate 3 Twist motion, make bolt create linear motion.Bolt 5 is connected with rotating disk 7 again, makes whole rotating disk 7 carry out directly Line moves.So that nozzle alignment lesion, then by the vibration of the 4th piezoelectric ceramic piece 9 by medicine storage device 11 In medicinal atomized after be discharged into pathological tissues surface through nozzle 12.
Step 3. first piezoelectric ceramic piece 2, under the effect of sine and cosine voltage, makes the first titanium alloy substrate 1 produce relatively Bolt part in the twist motion of its axis, the first titanium alloy substrate 1 does not has screw thread, bolt by surface both it Between frictional force be driven, bolt is rotated.Bolt 5 is connected with rotating disk 7 again, makes whole rotating disk 7 enter Row rotary motion.So that radiation under rotates 180 °, then produce ultrasound wave by the vibration of the 3rd piezoelectric ceramic piece 8, Pathological tissues is carried out real-time deep treatment, accelerates the drug absorption of lesion region, reach rapid healing purpose.At weight Multiple as above step, makes radiation under rotate again 180 °.
Step 4. lesion detection device 10 continues to detect the Cure of pathological tissues in real time, thus further Control amount of liquid medicine, be finally reached and detect the purpose integrated with treatment, when completing to one after the process of lesion, for Other lesion, repeat the above steps.
The above is only preferred implementation of the present utility model, it is noted that for the ordinary skill of the art For personnel, can also make some improvement on the premise of without departing from this utility model principle, these improvement also should be regarded as Protection domain of the present utility model.

Claims (1)

1. a vascular drug delivery therapy equipment based on Piezoelectric Driving, it is characterised in that: include the first titanium alloy substrate (1), The first piezoelectric ceramic piece (2), the second titanium alloy substrate (3) that are installed on the first titanium alloy substrate (1), it is installed on The second piezoelectric ceramic piece (4) on second titanium alloy substrate (3), bolt (5), radiation under (6), rotating disk (7), 3rd piezoelectric ceramic piece (8), the 4th piezoelectric ceramic piece (9), the lesion detection device (10) containing photographic head, medicine Storage device (11) and nozzle (12), described first titanium alloy substrate (1) is formed through first titanium alloy-based First hole of body (1) left and right side, the second titanium alloy substrate (3) is also formed through the second titanium alloy substrate (3) Second hole of left and right side, described bolt (5) right-to-left is arranged in the second hole, the first hole successively, bolt (5) Left-end point be positioned in the first titanium alloy substrate (1), the right end of bolt (5) extends beyond the second titanium alloy substrate (3) Right edge outside, the bolt partial outer face being positioned in the first hole is smooth, and the inner surface in the first hole is also smooth, The inner surface in bolt outer surface and the first hole is matched in clearance, and the bolt partial outer face being positioned in the second hole is screw-like , the inner surface in the second hole is smooth, and the right end thread of described bolt (5) is connected to the lateral edges of rotating disk (7), Described radiation under (6) is installed on the cental axial position of rotating disk (7), described radiation under (6) is positioned under rotating disk (7) The position of side is provided with a cavity (13), and described 3rd piezoelectric ceramic piece (8) is installed on rotating disk (7) and cavity (13) Between radiation under (6) on, described 4th piezoelectric ceramic piece (9) is installed on the inside bottom surface of cavity (13), Described nozzle (12) and lesion detection device (10) lay respectively at the left and right sides of radiation under (6) lower surface, described Medicine storage device (11) is positioned between the 4th piezoelectric ceramic piece (9) and nozzle (12).
CN201620198345.7U 2016-03-15 2016-03-15 Blood vessel drug treatment device based on piezoelectricity drive Withdrawn - After Issue CN205649728U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201620198345.7U CN205649728U (en) 2016-03-15 2016-03-15 Blood vessel drug treatment device based on piezoelectricity drive

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201620198345.7U CN205649728U (en) 2016-03-15 2016-03-15 Blood vessel drug treatment device based on piezoelectricity drive

Publications (1)

Publication Number Publication Date
CN205649728U true CN205649728U (en) 2016-10-19

Family

ID=57356523

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201620198345.7U Withdrawn - After Issue CN205649728U (en) 2016-03-15 2016-03-15 Blood vessel drug treatment device based on piezoelectricity drive

Country Status (1)

Country Link
CN (1) CN205649728U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105833418A (en) * 2016-03-15 2016-08-10 南京航空航天大学 Vascular administration therapy equipment based on piezoelectric driving and working method of vascular administration therapy equipment

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105833418A (en) * 2016-03-15 2016-08-10 南京航空航天大学 Vascular administration therapy equipment based on piezoelectric driving and working method of vascular administration therapy equipment

Similar Documents

Publication Publication Date Title
CN204017140U (en) A kind of ultrasonic micropin compound transdermal delivery device
US20120259311A1 (en) Fat removal device and obesity treatment
CN208641537U (en) A kind of transdermal delivery device
CN109806148A (en) A kind of naked joint fumigating nursing device of foot convenient for adjusting adjustable height
CN105833418A (en) Vascular administration therapy equipment based on piezoelectric driving and working method of vascular administration therapy equipment
CN205649728U (en) Blood vessel drug treatment device based on piezoelectricity drive
CN106730078A (en) A kind of built-in ultrasonic wave cup
CN112007287A (en) Auxiliary therapeutic apparatus for rehabilitation of diabetic foot disease patient
CN104587567A (en) Preparation method for miniature hollow silicon needle
CN202822479U (en) Uremia skin dialysis treatment device
CN101204350A (en) Comprehensive treatment of severe cold and its special equipment
CN201283161Y (en) Disposal cotton swab for nasal administration
CN205215439U (en) Medicine ware is smeared to pigskin skin
CN203524960U (en) Fumigation type meibomian gland massager
Lee et al. The mechanism of sonophoresis and the penetration pathways
CN205235148U (en) Insulin nasal administration device
CN207306982U (en) A kind of adjustable transdermal delivery device
CN105727438A (en) Spiral micro-needle wrinkle removal device and wrinkle removal method
CN207125897U (en) A kind of infusion bottle with automatic flushing function
CN206621657U (en) A kind of elastic micropin containing solvable syringe needle
CN204379722U (en) A kind of diabetes mellitus therapeutic device
CN103520831A (en) Liquid medicine ultrasonic therapy circulatory system
CN204134035U (en) Ultrasonic dosing treatment comb
CN202169019U (en) Device for treating disease merging small intestine meridian and stomach meridian
CN202761895U (en) Bladder and prostate cleaning and medicine delivering tube

Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
AV01 Patent right actively abandoned
AV01 Patent right actively abandoned
AV01 Patent right actively abandoned

Granted publication date: 20161019

Effective date of abandoning: 20220422

AV01 Patent right actively abandoned

Granted publication date: 20161019

Effective date of abandoning: 20220422