CN205235148U - Insulin nasal administration device - Google Patents

Insulin nasal administration device Download PDF

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Publication number
CN205235148U
CN205235148U CN201521010383.7U CN201521010383U CN205235148U CN 205235148 U CN205235148 U CN 205235148U CN 201521010383 U CN201521010383 U CN 201521010383U CN 205235148 U CN205235148 U CN 205235148U
Authority
CN
China
Prior art keywords
box body
needle tubing
insulin
fixed block
step motor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201521010383.7U
Other languages
Chinese (zh)
Inventor
张升校
吉晨晖
王磊
马小雯
李玉峰
裴宇恒
曹丽君
李满
李光来
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Individual
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Priority to CN201521010383.7U priority Critical patent/CN205235148U/en
Application granted granted Critical
Publication of CN205235148U publication Critical patent/CN205235148U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model belongs to the technical field of the medicine apparatus, concretely relates to insulin nasal administration device. The utility model provides an insulin is dosed and is had local lesion, the easy infection and painful problem. The utility model discloses insulin nasal administration device, set up two sets of syringes in the box body, every set of syringe is by the needle tubing, liquid separation head, the fixed block, the propeller, the lead screw, shaft coupling and step motor constitute, liquid separation head be located the needle tubing the exit and the needle tubing communicate with each other, the import of needle tubing is connected with the fixed block, the propeller sets up in the needle tubing, the other end of lead screw passes the output shaft of fixed block through shaft coupling and step motor and is connected, be equipped with stepper motor controller in the box body, stepper motor controller's operating panel sets up the bottom at the box body, stepper motor controller is connected with two step motor, two liquid separation head are connected with the hose, the outer tip of hose extends to the outside of box body and connects a nose bag, the liquid hole has been seted up out on the nose bag.

Description

A kind of insulin intranasal medicator
Technical field
The utility model belongs to medicine instrument technical field, is specifically related to a kind of insulin intranasal medicator.
Background technology
Insulin is widely used in treating diabetes. What is interesting is, large quantity research shows: insulin also has powerfulNeuroprotective function: diabetes have been considered to as sacred diseases such as Alzheimer disease, Parkinson's, vascular dementiasAn important risk factor is found the impaired and insulin receptor of insulin signaling desensitization phenomenon in the brain in patients of these diseases,Insulin, as the nerve growth factor in a brain, can activate the propagation of dendron regeneration and stem cell, the growth that this is importantThe infringement of factor signal can cause dull-witted generation. Research find, in brain endogenous insulin can with its receptors bind, protectProtect the neuron under oxidative stress status, inhibited apoptosis, promotes cell repair, promotes that neuron proliferation and nerve cell are longThe projection making new advances, has obvious neuroprotection, and then affects brain activity and cognitive function and memory capability. But traditionalWhen insulin lumbar injection, insulin is difficult to see through blood-brain barrier, and the neuroprotection of insulin can not well be brought into play.
How insulin is by intravenous drip or hypodermic injection administration at present. Intravenous drip enters to be applicable to partial hospitalization patient, therefore pancreas isletThe hypodermic injection application of element is more extensive. But hypodermic injection insulin problem is many: the first, local lesion. InsulinLong-term subcutaneous injection, physics or chemical irritation can cause local organization blood circulation disorder, and local swelling, scleroma form, shadowThe absorption that rings insulin, further causes hypodermis degenerative atrophy, even occurs necrosis producing dysfunction. The second, senseDye. Diabetic organizes sugar content high, thereby is beneficial to the breeding of bacterium, and patient, if do not noted skin health, does not note when injectionMeaning sterile working, makes bacterium more easily invade body, and in addition, diabetic's resistance restoring force is all poor, makes to infect moreEasily further expand. The 3rd, pain. The about 2-4mm of human skin thickness, nerve endings is densely distributed, to stimulating sensitivity.Traditional subcutaneous injection method, is 30-40 degree angle with needle body and thrusts, and the length that syringe needle is walked in skin is greater than skin thickness,Larger to skin and nerve ending damage, and inserting needle speed is slow, and patient's feels pain is obvious.
Utility model content
There is the problem of local lesion, easy infection and pain in the utility model, a kind of pancreas is provided mainly for current insulin administrationIsland element intranasal medicator.
The utility model is to address the above problem the technical scheme of taking to be:
A kind of insulin intranasal medicator, comprises box body, wherein: the two cover syringes that be arranged in parallel in box body, every cover injectionDevice is all made up of needle tubing, liquid-dividing head, fixed block, propeller, leading screw, shaft coupling and stepper motor, and liquid-dividing head is positioned at needle tubingExit and and needle tubing communicate, the import of needle tubing is connected with fixed block, propeller be arranged on needle tubing interior and with one end of leading screwBe connected, the other end of leading screw is connected by the output shaft of shaft coupling and stepper motor through fixed block, is provided with step in box bodyEnter electric machine controller, the guidance panel of controllor for step-by-step motor is arranged on the bottom of box body, controllor for step-by-step motor and two steppingsMotor is connected, and two liquid-dividing heads are all connected with flexible pipe, and the outer end of flexible pipe extends to the outside of box body and connects a nose capsule,On nose capsule, offer fluid hole, being provided with power supply in the side of box body is stepper motor and controllor for step-by-step motor power supply.
The utility model adopts technique scheme, from nasal-cavity administration, is the abundant absorption of guaranteeing dose when administration, need to give againAfter medicine, rinse with physiological saline, therefore need two trocar tubes, the utility model utilizes two stepper motors to realize accurate administrationAnd flushing, when use, under the control of controllor for step-by-step motor, carry out, on guidance panel, set the amount of administration and flushingAmount, stepper motor can rinse completing after administration, then by be exactly nose capsule and flexible pipe be all soft, patient just can root like thisAccording to the sensation of oneself, nose capsule is fully filled in to nostril and carry out administration, therefore, compared with prior art, the utlity model has followingBeneficial effect:
The first, local excitation is little. By nasal-cavity administration, avoided hypodermic injection repeatedly to the stimulation of local organization cause damage andCause pain, simultaneously rich blood vessel in schneiderian membrane, has improved the bioavilability of insulin. The second, reduce infection. TraditionInjection of insulin before first need skin degerming, also need injection site rotation simultaneously, again should also be noted that and avoid reusingInjection needle. Ignore above any link and all can cause the incidence infecting to increase, by nasal-cavity administration, well reduced skinThe chance that skinfeel is dyed, has improved patient's compliance. The 3rd, not only can play blood sugar reducing function; Can also be without blood-brain barrier,Transport by olfactory nerve axoplasm, directly into encephalic, prevention and treatment are dull-witted. The 4th, can low dose of administration, accurately control and giveDose. The 5th, after administration, there is washing pipe device, ensure the release completely of medicine, reduce to greatest extent residual. The 6th, operation letterJust, can complete above-mentioned two processes by guidance panel. The 7th, device is light and handy, and portable, cost is low.
Brief description of the drawings
Fig. 1 is structural representation of the present utility model;
Fig. 2 is the A-A profile of Fig. 1;
Fig. 3 is the B-B profile of Fig. 1.
Detailed description of the invention
Embodiment 1
A kind of insulin intranasal medicator, as shown in Figure 1, Figure 2 and Figure 3, comprises box body 1, in box body 1, be arranged in parallelTwo cover syringes 2, every cover syringe 2 is all by needle tubing 3, liquid-dividing head 4, fixed block 5, propeller 6, leading screw 7, shaft coupling8 and stepper motor 9 form, liquid-dividing head 4 be positioned at needle tubing 3 exit and and needle tubing 3 communicate, the import of needle tubing 3 with fixPiece 5 is connected, and propeller 6 is arranged in needle tubing 3 and is connected with one end of leading screw 7, and the other end of leading screw 7 is through fixingPiece 5 is connected with the output shaft of stepper motor 9 by shaft coupling 8, is provided with controllor for step-by-step motor 10, stepping in box body 1The guidance panel 15 of electric machine controller 10 is arranged on the bottom of box body 1, controllor for step-by-step motor 10 and two stepper motor 9 phasesConnect, two liquid-dividing heads 4 are all connected with flexible pipe 11, and the outer end of flexible pipe 11 extends to the outside of box body 1 and connects oneNose capsule 12 offers fluid hole 13 on nose capsule 12, is provided with power supply 14 for stepper motor 9 and stepping electricity in the side of box body 1Machine controller 10 is powered.

Claims (1)

1. an insulin intranasal medicator, comprises box body (1), it is characterized in that: two cover notes be arranged in parallel in box body (1)Emitter (2), every cover syringe (2) is all by needle tubing (3), liquid-dividing head (4), fixed block (5), propeller (6), leading screw(7), shaft coupling (8) and stepper motor (9) composition, liquid-dividing head (4) is positioned at exit and the needle tubing (3) of needle tubing (3)Communicate, the import of needle tubing (3) is connected with fixed block (5), propeller (6) be arranged in needle tubing (3) and with leading screw (7)One end be connected, the other end of leading screw (7) is defeated by shaft coupling (8) and stepper motor (9) through fixed block (5)Shaft is connected, and is provided with controllor for step-by-step motor (10) in box body (1), the guidance panel of controllor for step-by-step motor (10)(15) be arranged on the bottom of box body (1), controllor for step-by-step motor (10) is connected with two stepper motors (9), twoLiquid-dividing head (4) is all connected with flexible pipe (11), and the outer end of flexible pipe (11) extends to the outside of box body (1) and connects oneIndividual nose capsule (12) offers fluid hole (13) on nose capsule (12), is provided with power supply (14) for step in the side of box body (1)Enter motor (9) and controllor for step-by-step motor (10) power supply.
CN201521010383.7U 2015-12-08 2015-12-08 Insulin nasal administration device Expired - Fee Related CN205235148U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201521010383.7U CN205235148U (en) 2015-12-08 2015-12-08 Insulin nasal administration device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201521010383.7U CN205235148U (en) 2015-12-08 2015-12-08 Insulin nasal administration device

Publications (1)

Publication Number Publication Date
CN205235148U true CN205235148U (en) 2016-05-18

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201521010383.7U Expired - Fee Related CN205235148U (en) 2015-12-08 2015-12-08 Insulin nasal administration device

Country Status (1)

Country Link
CN (1) CN205235148U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105288834A (en) * 2015-12-08 2016-02-03 李光来 Nasal insulin delivery device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105288834A (en) * 2015-12-08 2016-02-03 李光来 Nasal insulin delivery device

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Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160518

Termination date: 20171208