CN205461116U

CN205461116U - Flavonoid's extraction element

Info

Publication number: CN205461116U
Application number: CN201620044744.8U
Authority: CN
Inventors: 周雄
Original assignee: Ningbo University
Current assignee: Ningbo University
Priority date: 2016-01-18
Filing date: 2016-01-18
Publication date: 2016-08-17
Anticipated expiration: 2026-01-18

Abstract

The utility model discloses a flavonoid's extraction element, characteristics are including the cauldron body, the condenser pipe, the stopcock of bleeding, air exhaust device and standard bottle plug, the internal fixed division board that is provided with of cauldron, fall into independent first cavity and second cavity with the cauldron body, the psammitolite of upper end for filtering usefulness of division board, the upper end of first cavity is provided with first bottleneck, the upper end of second cavity is provided with the second bottleneck, first bottleneck and second bottleneck are the standard mouth, bleed stopcock and first bottleneck in the stopcock, the second bottleneck matches, the gas -exhaust branch pipe who bleeds in the stopcock is connected with air exhaust device, the advantage uses this extraction element to carry out drawing of flavonoid, convenient operation, high efficiency, and the whole process of drawing is all accomplished in the cauldron body in succession moreover, has avoided drawing the transfer operation of result in different containers to avoid the transfer loss of result, improved the yield of result.

Description

A kind of extraction element of flavone compound

Technical field

This utility model relates to the device in laboratory for extraction of substance, particularly relates to the extraction element of a kind of flavone compound.

Background technology

Flavone compound is distributed widely in plant kingdom, general many presented in glycosides spending, in leaf, the tissue such as fruit.Due to flavonoid glycoside many tools acidity, it is soluble in alkaline water, therefore can use alkalescence water extraction, then potass extraction liquid furnishing is acid, flavonoid glycoside gets final product Precipitation, as rutin, Hesperidin, the extraction of baicalin all use said method.

At present, it is (as a example by extracting rutin from the Flos Sophorae Immaturus) that laboratory extracts the method for flavone compound: add the Flos Sophorae Immaturus and the water boil of about 6 times amount in the round-bottomed flask connecting condensing tube, being slowly added into lime cream under stirring to pH is 8～9, the most micro-boiling 20～30 minutes, pour in suction funnel sucking filtration while hot into, obtain filtrate；Residue adds the water boil of 4 times amount, sucking filtration while hot again in refunding former bottle；Merging filtrate is in another round-bottomed flask, and under conditions of 60～70 DEG C, with concentrated hydrochloric acid, filtrate being adjusted to pH is 5, stands 24 hours after stirring evenly, Precipitation, pours sucking filtration in suction funnel into, obtains precipitate, with water, precipitate is washed till neutrality, is dried in 60 DEG C after sucking filtration, obtains rutin crude product.If rutin crude product is put into round-bottomed flask boiling water recrystallization again, sucking filtration obtains precipitate, and 70～80 DEG C can obtain rutin sterling after drying.Loaded down with trivial details from the laboratory extraction step of flavone compound seen from above operating process, whole extraction process needs constantly to carry out transfer operation between round-bottomed flask and suction funnel, and this inevitably exists bigger product loss.

Summary of the invention

Technical problem to be solved in the utility model is to provide a kind of easy to operate, efficient, and can avoid the extraction element of the flavone compound of the transfer loss of product.

The technical scheme that the above-mentioned technical problem of this utility model solution is used is: the extraction element of a kind of flavone compound, including kettle, condensing tube, bleed pipe close, air extractor and standard bottle stopper, it is fixedly installed demarcation strip in described kettle, described kettle is divided into the first independent chamber and the second chamber, the upper end of described demarcation strip is the core filtered, the upper end of the first described chamber is provided with the first bottleneck, the upper end of the second described chamber is provided with the second bottleneck, the first described bottleneck and the second described bottleneck are standard mouth, the described pipe close bled in pipe close and the first described bottleneck, the second described bottleneck coupling, the described suction branch bled in pipe close is connected with described air extractor.

Described demarcation strip is S type, liquid flowing when filtering can be made more smooth and easy, filter thoroughly.

Described condensing tube is spherical condensation tube.

Compared with prior art, the utility model has the advantages that the extraction using this extraction element to carry out flavone compound, easy to operate, efficient, and whole extraction process is all continuously finished in kettle, avoid extraction product transfer operation in different vessels, thus avoid the transfer loss of product, improve the yield of product.

Accompanying drawing explanation

Fig. 1 is this utility model connection diagram of step (1) when extracting operation；

Fig. 2 is this utility model connection diagram of step (2) when extracting operation；

Fig. 3 is this utility model connection diagram of step (5) when extracting operation.

Detailed description of the invention

Below in conjunction with accompanying drawing embodiment, this utility model is described in further detail.

As shown in the figure, a kind of extraction element of flavone compound, including kettle 1, spherical condensation tube 2, bleed pipe close 3, air extractor (not shown) and standard bottle stopper 4, the demarcation strip 5 of S type it is fixedly installed in kettle 1, kettle 1 is divided into the first independent chamber 11 and the second chamber 12, the upper end of demarcation strip 5 is the core 51 filtered, the upper end of the first chamber 11 is provided with the first bottleneck 13, the upper end of the second chamber 12 is provided with the second bottleneck 14, first bottleneck 13 and the second bottleneck 14 are standard mouth, bleed the pipe close in pipe close 3 and the first bottleneck 13, second bottleneck 14 mates, the suction branch bled in pipe close 3 is connected with air extractor (not shown).

The concrete operations carrying out flavone compound extraction with this extraction element are: (as a example by extracting rutin from the Flos Sophorae Immaturus)

(1), in the first chamber 11 of kettle 1, the Flos Sophorae Immaturus and the water of about 6 times amount are added, first bottleneck 13 of the first chamber 11 connects condensing tube 2, standard bottle stopper 4 on the second bottleneck 14 top plug of the second chamber 12, as shown in Figure 1, boil, reflux, then removing condensing tube 2, being slowly added into lime cream while stirring to pH in the first chamber 11 is 8～9, the most micro-boiling 20～30 minutes after connecting condensing tube 2；

(2), condensing tube 2 is removed, standard bottle stopper 4 on the first bottleneck 13 top plug, the second bottleneck 14 connects pipe close 3 of bleeding, and turn 90 degrees kettle side, as in figure 2 it is shown, the Flos Sophorae Immaturus and water is made to concentrate on core 51 around, after sucking filtration, filtrate is filled in the second chamber 12；

(3), by kettle 1 righting, residue drops back into the bottom of the first chamber 11, then toward after adding the water boil of 4 times amount in the first chamber 11, same to step (2) carries out sucking filtration while hot, and filtrate is incorporated in the second chamber 12；

(4), removing pipe close 3 of bleeding, under conditions of 60～70 DEG C, with concentrated hydrochloric acid, the filtrate in the second chamber 12 being adjusted to pH is 5, stands 24 hours, Precipitation after stirring evenly；

(5), standard bottle stopper 4 on the second bottleneck 14 top plug, first bottleneck 13 connects pipe close 3 of bleeding, kettle 1 side is turned about 120 degree, as shown in Figure 3, make the second chamber 12 treats that filtrate is near core 51, not making hydrorrhea to be filtered cross the high point of core 51, after sucking filtration, precipitate stays in the second chamber 12；

(6), with water, the precipitate in the second chamber 12 is washed till neutrality, then the mode sucking filtration by step (5), then the precipitate of sucking filtration gained is dried at about 60 DEG C, obtains rutin crude product；

(7), rutin crude product is used boiling water recrystallization in the second chamber 12, with the mode sucking filtration of step (5), be precipitated thing, be then dried at 70～80 DEG C, obtain rutin sterling.

Claims

1. the extraction element of a flavone compound, it is characterized in that including kettle, condensing tube, bleed pipe close, air extractor and standard bottle stopper, it is fixedly installed demarcation strip in described kettle, described kettle is divided into the first independent chamber and the second chamber, the upper end of described demarcation strip is the core filtered, the upper end of the first described chamber is provided with the first bottleneck, the upper end of the second described chamber is provided with the second bottleneck, the first described bottleneck and the second described bottleneck are standard mouth, the described pipe close bled in pipe close and the first described bottleneck, the second described bottleneck coupling, the described suction branch bled in pipe close is connected with described air extractor.

The extraction element of a kind of flavone compound the most as claimed in claim 1, it is characterised in that described demarcation strip is S type.

The extraction element of a kind of flavone compound the most as claimed in claim 1, it is characterised in that described condensing tube is spherical condensation tube.