CN205433997U - Die cavity vein filter of can changeing - Google Patents

Die cavity vein filter of can changeing Download PDF

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Publication number
CN205433997U
CN205433997U CN201521095488.7U CN201521095488U CN205433997U CN 205433997 U CN205433997 U CN 205433997U CN 201521095488 U CN201521095488 U CN 201521095488U CN 205433997 U CN205433997 U CN 205433997U
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China
Prior art keywords
filter
degradable
drainage screen
cylindric
transformant
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CN201521095488.7U
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Chinese (zh)
Inventor
曾凡艳
杨永森
罗鹏
张芳芳
刘光
王广卉
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Shanghai Shape Memory Alloy Material Co Ltd
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Shanghai Shape Memory Alloy Material Co Ltd
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Abstract

The utility model discloses a die cavity vein filter of can changeing, a serial communication port, including cylindric vascular support, be equipped with the degradable filter screen in the cylindric vascular support, it is open that the degradable filter screen is both ends, and one end is big, structure that the other end is little. The utility model discloses a niTi alloy silk shape memory material is woven, and it is cylindric vascular supporting structure to stereotype through thermal treatment, and both ends are open. Use degradable polymer fiber silk to weave into a funnel type filter screen direct inside, as the vena cave filter. Internal back is implanted to the vena cave filter, through specific time quantum, and the degradation of filter house degradable ligature silk for the function of filtering, blocking the part of thrombus is suspend, and the filter is inside open -minded completely, but the filter keeps somewhere in the normal position, be equivalent to the support of an adherence, that is the function call has arrived the conversion.

Description

One can transformant vena cava filter
Technical field
This utility model relates to one can transformant vena cava filter.
Background technology
The acute disease that pulmonary infarction (Pulmonaryembolism, PE) is clinical onset rate, mortality rate is higher, its sickness rate intentions angiopathy the 3rd, it is only second to hypertension and coronary heart disease, its mortality rate is 25~30%.According to incompletely statistics, China has 35.5 ten thousand example Pulmonary Embolism Patients at present.
Pulmonary infarction is owing to the thrombus breaks loose of around deep venous thrombosis or right cardiac cavity enters pulmonary circulation, and blocking pulmonary artery or its branch are, and then a series of clinical pathology physiological changes based on pulmonary circulatory function obstacle of causing.Result of study shows, causes the thrombosis that the embolus 75~90% of pulmonary infarction derives from pelvic veins or deep veins of lower limb comes off.Thrombosis after coming off moves on to cardiopulmonary in caval vein system, causes pulmonary embolism.
Vena cava filter (Venacavafilter, VCF) it is to come off a kind of filtering device causing pulmonary embolism and design for prevention superior and inferior vena cave system embolus, can be used for anticoagulant and avoid and have acute pulmonary embolism or the patient of acute near-end (above knee) venous thrombosis.
Along with clinical technology and the development of manufacturing technology, performance and the implantation of vena cava filter have had significant progress.Vena cava filter is Interventional Radiography and the usual armarium of Vascular surgeons.In operation, by puncturing radicular vein or jugular mode and by vena cava filter implant cavity vein under contrastographic picture assists.Vena cava filter is divided into permanent filter and provisional filter (the most recyclable filter).Vena cava filter in early days is all permanent, insert after in caval vein and cannot take out with intervening mode, it also it is endovascular foreign body due to vena cava filter, there is the danger of induction thrombosis equally, therefore the client need long-term anticoagulant therapy after placed cavity vein filter, this just brings inconvenient and hemorrhage danger to patient.The invention of provisional filter, has not only acted as the effect of prevention pulmonary infarction, the most also avoids the risk of itself induction thrombosis.Insert provisional filter in the acute stage of patient's deep vein thrombosis of lower extremity, and after acute stage, the risk of thrombus breaks loose is drawn off with intervening mode when reducing again.
Vena cava filter in early days is designed to beveled structure more, intercepts thrombosis free in blood vessel.But, the design of this structure easily tilts in venous lumen, shifts.For preventing displacement or the drift of filter, in the middle of filter tinsel head end or metallic rod, increase barb structure, enable filter to be fixed in blood vessel wall.But, the tinsel of band agnail directly thrusts blood vessel wall, and blood vessel wall can cause certain damage, and the serious vein tube wall that pierces through causes hemorrhage, even thrusts the internal organs such as small intestinal, colon and causes infection.
Spindle-type filter has thick waist structure in design, can play a supporting role, and is difficult to.Wherein, within 2~3 weeks, can take out external after the implantation as provisional filter without agnail fixed pattern, the type having agnail fixing can not only be used for provisional filter, it is possible to is placed in the patient as permanent filter.Although this design serves preferable fixation, but, owing to after spindle-type filter many employings Nitinol pipe laser engraving, high-temperature shaping forms, there is wire breakage causes subside damage caval vein inwall, blood vessel embolism of filter constructions to cause the smooth equivalent risk of blood circulation, and document is the most repeatedly reported.
At present, the kind of vena cava filter is more, such as: the Chinese patent of Patent No. CN101491465A discloses a kind of vena cava filter, and this filter includes support component and filter element, filter element is fixed on support component, it is characterised in that described filter element is degradable filter element.After thromboembolism treatment completes, the filter element of filter is degraded the most voluntarily, it is not necessary to row removal surgery again, it is to avoid the intervention damage that operation is taken out and caused, and saves relevant apparatus expense, reduces treatment cost.
But, the degradation cycle of current degradable high polymer material is longer, even macromolecular fibre is degradable may need 3 months even six months, and degradation time is uncontrollable.
Summary of the invention
To be solved in the utility model be existing can transformant vena cava filter degradation time slow, the problems such as degradation cycle is uncontrollable.
In order to solve the problems referred to above, this utility model provides one can transformant vena cava filter, it is characterised in that, including cylindric intravascular stent, being provided with degradable drainage screen in cylindric intravascular stent, described degradable drainage screen is both ends open, and one end is big, the structure that the other end is little.
Preferably, during the degraded of described degradable drainage screen, its small end is first degraded;After small end degraded, bigger end is dispersed structure.
Preferably, described degradable drainage screen is funnel-shaped structure.
It is highly preferred that described degradable drainage screen is the funnel-shaped structure being woven into by degradable macromolecule cellosilk, its small end is formed by degradable ligation ring constraint.
Preferably, described degradable drainage screen is claw-like structures.
It is highly preferred that described degradable drainage screen is the integrated claw-like structures of degradable magnesium alloy material.
This utility model is main material with NiTi B alloy wire, in conjunction with degradable macromolecule silk material, by the method for braiding prepare can transformant vena cava filter.This filter includes supporting part and filter house two parts.
This utility model uses the braiding of NiTi B alloy wire shape-memory material, thermally treated is fixed to cylindric intravascular stent structure, both ends open.Degradable macromolecule cellosilk is used to be woven into a funnel type drainage screen, as vena cava filter the most internal.
Described vena cava filter fixed part is both ends open cribbing, NiTi B alloy wire be woven to monolayer netted, with the laminating of caval vein inwall closely.This support can also be the metal fiber wire such as rustless steel, titanium alloy braiding form, it is also possible to be non-degradable macromolecular fibre silk or degradable macromolecule cellosilk braiding form.
Filter house is infundibulate network structure, the braiding of n root (n=4/5/6/7/8) Biodegradable fibers silk form.Biodegradable fiber silk can be degradable magnesium alloy material, it is also possible to be degradable high polymer material.Biodegradable fiber silk one end is fixed on intravascular stent, and other end head is tied to form ring-type.The annular end of n root degradable silk is passed from ring by a biodegradable fiber silk, and is tied to form annulus dress.N root filter house filament diameter is relatively thick, and diameter range 0.3mm to 0.5mm, degradation cycle is long.Bottom filter house, annulus filament diameter is relatively thin, and diameter range 0.1mm to 0.2mm, degradation cycle is shorter.Additionally, the annular diameter scope 5mm to 8mm of fibrae circulares.
For the design of filter house filament diameter, being to ensure that thinner circular fiber is first degraded fracture, cause filter house malformation, filtration is interrupted or even loses.The cellosilk that then n root is thicker is the most gradually degraded, and is finally wholly absent.
After described vena cava filter implants, through special time period, filter house degradable ligature is degraded, it is interrupted for filtering, block the function of the parts of thrombosis, the most open-minded inside filter, but filter indwelling is in situ, be equivalent to an adherent support, that is function is converted.
This utility model have employed thickness combine macromolecular fibre silk, filament is first degraded, as a example by polylactic acid (PLA), about 20 days and start degraded, consistent for cycle time with the pulmonary vein thrombotic risk of patient.Degrading after thick macromolecular fibre silk, now this vena cava filter is to terminate filtering function, changes into adherent blood vessel direct.Realize the progressively degradation effect that degradation cycle is controlled.Compared with the vena cava filter that tradition rustless steel or nickel-titanium alloy material use cutting and solder technology to prepare, the method is simpler, easily operates, and material structure is stable, and mechanics elasticity is excellent.Technology maturation, it is not necessary to extra equipment and technique, cost is relatively low.
Compared with prior art, the beneficial effects of the utility model are:
1.NiTi alloy good biocompatibility, corrosion-resistant, possess super-elasticity, release aftershaping is effective;
2. filter house described in is degradation material, and after special time is degraded, vena cava filter intermediate filtered portion function is interrupted, the most open-minded inside filter, changes into an adherent support;
3. this vena cava filter is because being converted into adherent support, it is not necessary to second operation takes out, and alleviates patient painful.The most not depositing the occurrence risk of thrombotic complications at a specified future date after the implantation, patient need not take all the life anticoagulant, improves quality of life of patients;
4. these vena cava filter two ends are that intravascular stent structure plays fixation, and NiTi silk elasticity is high, and compliance is good, and intravascular stent structure is tightr with the laminating of caval vein inwall, fixation;
5. design without agnail, reduce the damage to caval vein blood vessel;
The most according to actual needs, this vena cava filter standing part diameter, length may be designed to plurality of specifications;
7.NiTi B alloy wire weaving method technology maturation, it is not necessary to extra equipment and technique, cost is relatively low.
Accompanying drawing explanation
Fig. 1 for this utility model provide a kind of can the structural representation of transformant vena cava filter;
Fig. 2 is the cross-sectional view of degradable drainage screen;
Fig. 3 is the cross-sectional view of cylindric intravascular stent;
Fig. 4 is the schematic diagram before degrading during this utility model use;
The schematic diagram of Partial digestion when Fig. 5 is this utility model use;
The schematic diagram that Fig. 6 is degradable when being this utility model use;
Fig. 7 for embodiment 1 provide a kind of can the structural representation of transformant vena cava filter;
Fig. 8 is the cross-sectional view of degradable drainage screen in embodiment 1;
Fig. 9 is the schematic diagram of degradable drainage screen its flat presentation in embodiment 1;
Figure 10 for embodiment 2 provide a kind of can the structural representation of transformant vena cava filter;
Figure 11 is the front view of degradable drainage screen in embodiment 2;
Figure 12 is the right view of Figure 11.
Detailed description of the invention
For making this utility model become apparent, hereby with preferred embodiment, and accompanying drawing is coordinated to be described in detail below.
As shown in figure-3, for this utility model provide a kind of can the structural representation of transformant vena cava filter, including cylindric intravascular stent 1, it is unilayered vessels support, plays a supportive role.Being provided with degradable drainage screen 2 in cylindric intravascular stent 1, described degradable drainage screen 2 is both ends open, and one end is big, the structure that the other end is little.
After this utility model enters human body, before degraded as shown in Figure 3;When described degradable drainage screen 2 is degraded, its small end is first degraded;After small end degraded, bigger end is dispersed structure (as shown in Figure 5), until degradable (as shown in Figure 6).
Embodiment 1
As Figure 7-9, degradable drainage screen 2 is woven by n root (n=4/5/6/7/8) Biodegradable fibers silk, and two ends are knotted into ring-type, and one end ties up on cylindric intravascular stent 1, the other end, by thinner ring-type biodegradable fiber silk ligation, forms a funnel type structure.
Through special time period, annular ligation cellosilk degraded, the degradable silk that other n root of filter house is thicker is carried the baby disappearance, funnel type filtration scatters (as shown in Figure 5), it is interrupted for filtering, block the function of the parts of thrombosis, the most open-minded inside filter, but filter indwelling is in situ, be equivalent to an adherent support, that is function is converted (as shown in Figure 6).
Ligation ring can be degradable high polymer material, such as: polylactic acid (PLA), polycaprolactone (PCL), PVOH acid esters (PGA), polyhydroxyalkanoate (PHB) etc., it is also possible to be degradable magnesium alloy material etc..
The vena cava filter prepared according to above-mentioned principle, structure and weaving method, it is also possible to be other metal wire materials such as stainless steel silk, titanium alloy wire, and non-degradable macromolecular fibre silk and degradable macromolecule cellosilk.
If filter house material is non-degradable material, then support can be considered permanent filter.
Embodiment 2
Difference from Example 1 is, the n root biodegradable fiber silk of degradable drainage screen 2 is substituted by NiTi fiber, or uses degradable magnesium alloy material, and as shown in figs. 10-12, degradable drainage screen 2 is the integrated claw-like structures of degradable magnesium alloy material.

Claims (6)

1. one kind can transformant vena cava filter, it is characterized in that, including cylindric intravascular stent (1), it is provided with degradable drainage screen (2) in cylindric intravascular stent (1), described degradable drainage screen (2) is both ends open, and one end is big, the structure that the other end is little.
The most as claimed in claim 1 can transformant vein filter, it is characterised in that during the degraded of described degradable drainage screen (2), its small end is first degraded;After small end degraded, bigger end is dispersed structure.
The most as claimed in claim 1 or 2 can transformant vein filter, it is characterised in that described degradable drainage screen (2) is funnel-shaped structure.
The most as claimed in claim 3 can transformant vein filter, it is characterised in that described degradable drainage screen is the funnel-shaped structure being woven into by degradable macromolecule cellosilk, its small end is formed by degradable ligation ring constraint.
The most as claimed in claim 1 or 2 can transformant vein filter, it is characterised in that described degradable drainage screen (2) is claw-like structures.
The most as claimed in claim 5 can transformant vein filter, it is characterised in that described degradable drainage screen (2) is the integrated claw-like structures of degradable magnesium alloy material.
CN201521095488.7U 2015-12-24 2015-12-24 Die cavity vein filter of can changeing Active CN205433997U (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108186159A (en) * 2018-03-02 2018-06-22 云南省第二人民医院 A kind of convertible inferior vena cava thrombosis filter
CN108309506A (en) * 2018-03-19 2018-07-24 威海维心医疗设备有限公司 Vena cava filter
CN110731832A (en) * 2018-07-20 2020-01-31 上海微创医疗器械(集团)有限公司 Inferior vena cava filter
WO2021227611A1 (en) * 2020-05-11 2021-11-18 上海蓝脉医疗科技有限公司 Filter
CN116919650A (en) * 2023-09-18 2023-10-24 北京心祐医疗科技有限公司 Absorbable filter

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108186159A (en) * 2018-03-02 2018-06-22 云南省第二人民医院 A kind of convertible inferior vena cava thrombosis filter
CN108309506A (en) * 2018-03-19 2018-07-24 威海维心医疗设备有限公司 Vena cava filter
CN108309506B (en) * 2018-03-19 2023-10-13 威海维心医疗设备有限公司 vena cava filter
CN110731832A (en) * 2018-07-20 2020-01-31 上海微创医疗器械(集团)有限公司 Inferior vena cava filter
CN110731832B (en) * 2018-07-20 2022-04-12 上海微创医疗器械(集团)有限公司 Inferior vena cava filter
WO2021227611A1 (en) * 2020-05-11 2021-11-18 上海蓝脉医疗科技有限公司 Filter
CN116919650A (en) * 2023-09-18 2023-10-24 北京心祐医疗科技有限公司 Absorbable filter
CN116919650B (en) * 2023-09-18 2024-01-19 北京心祐医疗科技有限公司 Absorbable filter

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