CN205947897U - Degradable vena cave filter - Google Patents

Abstract

The utility model discloses a degradable vena cave filter, including three -dimensional filter frame, the filter frame is the infundibulate, and the filter puts up and is provided with the continuous framework of several rotatoryly, the framework includes interior frame and the outline who extends and link to each other along the slant of filter frame axial, and the interior frame one end of extending to filter frame center is the pointed end of filter frame, and the ring frame of framework frame in the pointed end of filter frame is provided with the connection, the outer one end of extending of outline slant is the outer end of filter frame, and interior frame, outline and ring frame are the degradation material, and interior frame and ring frame's thickness is less than or equal to outline's thickness. Degradable vena cave filter realizes expansion and support in can stablizing tight anchor blood vessel well, and its structure is easily drawn in in addition, makes things convenient for very much operation implantation human, and the interior and effective filtration clot of stable fastening blood vessel along with time distributional degradation, can not produce and remain the foreign matter at last, the treatment of furthest help patient, and medical value is very high.

Description

A kind of degradable vena cava filter

Technical field

This utility model is related to medical apparatus and instruments, specifically a kind of degradable vena cava filter.

Background technology

Venous thromboembolism（VTE）Including deep venous thrombosis（DVT）And pulmonary infarction（PE）, it is one in worldwide Plant extremely common disease, have a strong impact on the quality of life of patient, in addition lethal.In general population, VTE sickness rate is according to statistics 1-3/1000, the generation of annual global range VTE close to 10,000,000, the generation number of cases of U.S. VTE per year over 900000, wherein 1/3rd directly result in death, account for the cause of the death the 3rd.DVT is multiple to be born in lower limb, because obstruction of blood return occur lower extremity swelling and distension, Pain, dysfunction, but it is back to pulmonary artery as after thrombus breaks loose through the right heart, may result in serious complication PE.From 1960 Year starts, IVCF（IVCF）In a large number, it is widely used in clinic and exceedes half a century, research confirms that IVCF can make Come off by deep vein thrombosis of lower extremity and cause the incidence rate of pulmonary embolism to drop to 0.9% ~ 5% by 60% ~ 70%, significantly reduce near Phase and PE incidence rate at a specified future date, improve recent general mortality rate and PE related mortality.

But IVCF no affects and increases DVT incidence rate at a specified future date to general mortality rate at a specified future date, permanent implanted cause a series of Such as postcava blocking, send out again pulmonary infarction, filter deformation and displacement, filter leg penetrate blood wall, filter fracture, infect etc. sternly Weight complication.Most patients need lifelong anticoagulant therapy, this not only adds psychology, the financial burden of patient, and cause one Fixed bleeding risk.Venothrombotic natural history makes patient only face the threat of PE within a period of time after lower limb DVT, that is, Make vena cava filter highly effective to prevention PE, patient is also temporary transient, therefore provisional vena cava filter to its demand Occur therewith with recuperability vena cava filter.China " expert of inferior vena cava filter implantation and removal surgery specification in 2011 Common recognition " is recommended to try one's best using provisional filter and be can be taken off filter, to reduce the correlation leading to because filter is inserted for a long time simultaneously Send out disease.The recyclable filter of current selectivity, because its long term complication is less, clinically applies more and more extensive, but Some recyclable filter reclaims unsuccessfully, and only 50% successfully being taken out after 3 months.And patient still needs to warp again Go through operation and increased cost.The factor that impact filter reclaims is a lot, and including filter displacement, deformation, fracture, filter barb punctures Postcava wall, adhesion, thrombosis in filter, filter tilts, recovering hook is adherent etc..

The bright IVCF of Stein statistics American National medical center data storehouse 50 Ge Zhoujidi district hospital data sheet Annual rate of growth is up to 16%, and global implantation amount conservative estimation reaches hundreds thousand of/year.China still lacks accurate VTE epidemic diseases at present Data, but the continuous improvement with clinicist's diagnosis consciousness and level and social senilization, domestic PE and DVT diagnoses and treatment Case load all improve year by year.In this class operation more than ten years of wide clinical application at home, in recent years implant quantity annual 6 ~ 100,000 Example, medical science and social value are huge.

The incidence rate of filter complication increases with the increase of the time of inserting, and PE risk As time goes on and Reduce.If there being a kind of filter, inserting in the high-risk stage of PE and tiding over After acute stage absorbed themselves or disappearance, will greatly reduce Due to filter take out difficult or insert for a long time, anticoagulant and the complication that causes.Therefore, preferable IVCF should be that structure is simple, Good biocompatibility, inserts conveniently, has preferable embolus capture ability, discharges accurate positioning and position is stable, will not cause Severe complication, will not substantially change the hemodynamics feature of IVC, both can retain the sufficiently long time in caval vein and protect Hold that IVC is unobstructed, can be degraded after the generation of effective prevention PE again or reclaim thus avoiding the correlation inserted and cause for a long time Complication.Biodegradable coronary artery bracket in 2007 has been applied to clinic, and degradable biological medical material includes poly- third friendship Ester, PGA and its copolymer in combination etc., are the high molecular polymers that U.S. FDA ratifies for human body implantation, extensively should For all kinds of medical materials.With material science and histological development, application new material and technique making can be degradable Filter, reducing IVCF complication should be no longer illusion.

Therefore, vena cava filter should be easily implantable human vas, can be stabilized in after surgery in blood vessel again simultaneously And effectively prevent phlebothrombosises blood coagulation, and take out until second operation can be exempted after human body recovery, such vena cava filter Effect the most appropriate could be provided for patient to greatest extent, and filter constructions many now all have different defects, need Improve.

Utility model content

In order to overcome the deficiencies in the prior art, this utility model provides one kind to be easily implantable, effective anticoagulation（Intercept blood Bolt）, and the degradable vena cava filter of energy step-wise dissolution.

This utility model solves its technical problem and be employed technical scheme comprise that：

A kind of degradable vena cava filter, including three-dimensional filter frame, described filter frame is in infundibulate, and filter frame is rotatably It is provided with several connected frameworks, described framework includes interior frame and the outer rim axially extending obliquely out along filter frame and being connected, The tip being filter frame to interior frame one end that filter frame center extends, and framework is provided with connection inner edge in the tip of filter frame The ring frame of frame, one end that described outer rim tiltedly stretches out is the outer end of filter frame, and interior frame, outer rim and ring frame are The thickness of degradation material, interior frame and ring frame is less than or equal to the thickness of outer rim.

As the improvement of technique scheme, corresponding two institutes with two neighboring framework in end of every described interior frame The one end stating outer rim connects altogether, and the other end of two outer rim is connected to the outer end of filter frame, interior frame and described ring frame Thickness is less than the thickness of outer rim.

As the improvement further of technique scheme, described interior frame arc is to lateral bend in filter frame, described outside Frame arc is to lateral bend outside filter frame.

Further, described framework is provided with, in the outer end of filter frame, the card tiltedly stretching out and with outer rim formation angle Pawl.

Further, interior frame, outer rim, ring frame and the claw of stating framework are formed in one.

Further, often adjacent two described framework parts are crisscross arranged, and two adjacent described outer rim are intersected intersecting Connect.

Further, the filter frame outer end that the adjacent described outer rim of each two stretches out axially height setting straggly.

Further, described filter frame is additionally provided with the absorbable silk thread through described framework, described absorbable silk thread and frame Body constitutes filter mesh, and absorbable silk thread is degradable material.

Further, described absorbable silk thread forms interior loop and/or outer around connecting described interior frame and outer rim respectively Coil.

Further, described absorbable silk thread is also connected with the outer end of filter frame and most advanced and sophisticated ring frame forms separator bar.

The beneficial effects of the utility model are：Degradable vena cava filter of the present utility model can stablize tight anchor well Ink vessel transfusing is realized expanding and is supported, and its structure is easy to draw in, very convenient operation implantation human body, stably fastens Ink vessel transfusing simultaneously Effectively filter clot, finally stepwise degradation in time, retained foreign body will not be produced, help patient, medical treatment to greatest extent It is worth very high.

Brief description

With reference to the accompanying drawings and examples this utility model is further illustrated.

Fig. 1 is a kind of structural representation of this utility model embodiment inside view；

Fig. 2 is the structural side view of Fig. 1 embodiment；

Fig. 3 is the structural representation of Fig. 1 embodiment external view；

Fig. 4 is the structural representation of this utility model another embodiment external view；

Fig. 5 is the structural front view of Fig. 4 embodiment.

Specific embodiment

Arbitrary legend of reference picture 1- Fig. 3, a kind of a kind of embodiment of degradable vena cava filter of the present utility model, bag Include the filter frame of solid, described filter frame is in class infundibulate or similar with Semen Castaneae profile, filter frame is rotationally symmetrical or asymmetrically It is provided with several petal shapes or diamond shaped or other shapes and connected framework 1, described framework 1 is included along filter frame axially The interior frame 11 extending obliquely out and being connected and outer rim 12, the point being filter frame to interior frame 11 one end that filter frame center extends End, and framework 1 is provided with the ring frame 13 connecting each interior frame 11 one end in the tip of filter frame, described ring frame 13 is preferred For circle, may also set up rectangular, rhombus or other shapes, described outer rim 12 tiltedly stretches out and at least every two intersecting shapes The one end becoming is the outer end of filter frame, and filter frame is additionally provided with the absorbable silk thread constituting filter mesh in framework 1, can reduce Gap, strengthens thrombosis filter effect, and described absorbable silk thread is degradable material, preferably PGA or PGLA material, its degradation time Be about 3 to 6 months, absorbable silk thread can by binding, wear and the mode such as connect and be connected in the framework 1 of filter frame, and interior frame 11, Outer rim 12 and ring frame 13 are degradation material and make, preferably memory elasticity preferable PPDO or PCL material, during its degraded Between be about 6 ~ 12 months, absorbable silk thread and interior frame 11, outer rim 12 form mesh or mesh can intercept, intercept bulk blood Block and do not affect blood and pass through, absorbable silk thread correspondence was degraded split after the time that blood vessel recovers, and mesh or mesh decompose；With When interior frame 11 and ring frame 13 thickness be less than or equal to outer rim 12 thickness, in interior frame 11 and each outer wall of ring frame 13 Degrade with the outer rim 12 abutting tunica intima prior to part in the presence of contacting blood or dissolve, therefore interior frame 11 and ring frame 13 separate first from filter frame and flow away absorption with blood, and outer rim 12 is further launched after losing the restriction of interior frame 11 Thus more fully support abutting tunica intima, subsequently when angiopathy is cured, outer rim 12 also natural degradation, absorption, thorough Bottom completes treating cardiovascular disease.

As the improvement of above-mentioned embodiment, described absorbable silk thread is preferably simultaneously respectively around the described interior frame 11 of connection Form interior loop 31 and exterior loop 32 with outer rim 12, also can select a setting, interior loop 31 is preferably from interior frame 11 and outer rim The end of 12 connections passes through, and exterior loop 32 preferably passes through in the middle part of outer rim 12, thus ring frame 13 and interior loop 31,32 are formed Parallel coil, can absorb outer end and the most advanced and sophisticated ring frame 13 formation separator bar 33 that silk thread is also connected with filter frame simultaneously, and point Inside line 33 is from filter frame abut interior loop 31 again outside filter frame abut exterior loop 32 be attached, separator bar 33 with interior Coil 31 and exterior loop 32 are vertical or near vertical；As one kind preferably, framework 1 is provided with and corresponds to through described absorbable silk thread Aperture realize connecting, or framework 1 and absorbable silk thread are simultaneously fit constitutes.

As the improvement further of above-mentioned embodiment, described interior frame 11 from filter frame most advanced and sophisticated to outer rim 12 arc to Lateral bend in filter frame, described outer rim 12 is from interior frame 11 to filter frame outer end arc to lateral bend filter frame, filter frame Axial outer edge is S-shaped or reverse-s shape, preferably improves the elasticity of framework 1；And outer rim 12 arc is outwards, therefore abut Ink vessel transfusing Film is more appropriate, and in addition interior frame 11 also can straight be arranged.

Further, described framework 1 in the outer end of filter frame be provided with tiltedly stretch out and with outer rim 12 formed angle Claw 14, claw 14 outer rim 12 and tunica intima support abut be can holding grappling filter frame position in the blood vessel, Avoid because influence of blood flow displacement.

Preferably, the thickness of described interior frame 11 and ring frame 13 is preferably smaller than the thickness of outer rim 12, so that it is guaranteed that interior Frame 11 and ring frame 13 are first degraded and are separated, and purposefully arrange corresponding on interior frame 11, outer rim 12 and ring frame 13 Breach, to realize more preferable local, middle separated and dissolved；Described interior frame 11 and outer rim 12 are symmetrically arranged respectively Have four and eight, one end of the end of every interior frame 11 and two outer rim 12 connects, this two outer rim 12 another End is connected to filter frame outer end, and that is, each two framework 1 has an interior frame 11, therefore framework 1 is symmetrically provided with four, Avoided to greatest extent during the effect of filter frame in human vas internal shift or biasing by regular shape.

Preferably, the interior frame 11 of described framework 1, outer rim 12, ring frame 13 and claw 14 are formed in one, then integrate Absorbable silk thread, therefore filter filter frame is made up of the high polymer blending of two kinds of degradables, can use curtain coating extrusion molding or cutting method first Make the bar of this blended polymer, recycle 3D laser printer to sinter this bar into designed three-dimensional shape.Also may be used Using traditional Shooting Technique by the directly molding in a mold of this three-dimensional shape, the intensity of one of which high polymer is higher, in filter Play a supportive role in device, another kind of high polymer intensity is relatively low, but elasticity is preferably it is ensured that the elasticity of filter is suitable for intervening handss Play, after art, and implantation postcava, the effect being close to tunica intima；By adjusting the molecular weight of this blended polymer, also can be by The degraded deadline controls between particular requirement, so when designing the three-dimensional shape of this filter, its material of different parts Thickness be designed to inconsistent, thus can control filter each position degraded the deadline inconsistent, thus can accomplish in the middle of filter Partly first degrade, be close to partly finally degrading of tunica intima.

With reference to Fig. 4 and Fig. 5, another embodiment of the present utility model, including the filter frame in funnel shaped, described filter frame Rotationally symmetrical or be asymmetrically provided with several petal shapes or other shapes and connected framework 1, described framework 1 includes edge Interior frame 11 and outer rim 12 that filter frame axially extends obliquely out and is connected, interior frame 11 one end of the framework 1 inside filter frame The tip extending composition filter frame is gathered at oblique filter frame center, and described interior frame 11 connects into ring frame in the tip of filter frame 13, described ring frame 13 is preferably circular, may also set up rectangular, rhombus or other shapes, outside the framework 1 outside filter frame Frame 12 tiltedly stretches out and at least every two outer ends intersected for filter frame.The end of every interior frame 11 and two outer rim 12 one end connects, and the other end of this two outer rim 12 is connected to filter frame outer end, and that is, each two framework 1 has an inner edge Frame 11.Often adjacent two described framework 1 parts are crisscross arranged, and two adjacent described outer rim 12 intersect intersecting connection, with When the axially height setting straggly of the filter frame outer end that stretches out of the adjacent outer rim of each two 12, constitute one high and one low between Every so that filter frame draws in less, it is more convenient implantation；In addition the thick scope of frame of interior frame 11 and outer rim 12 is 1mm To 1.5mm, and the thickness of interior frame 11 is less than or equal to the thickness of outer rim 12.

Compared with embodiment one, framework 1 is made the space between interior frame 11 and outer rim 12 reduce because staggered by it, thus Formed and so that the larger clot producing in strainer filtering post-surgical vascular is not easily passed through, and intensity is high.

In the same manner, interior frame 11 is from filter frame tip to outer rim 12 arc to lateral bend in filter frame, described outer rim 12 From interior frame 11 to filter frame outer end arc to lateral bend filter frame, filter frame axial outer edge is S-shaped or reverse-s shape.

Described framework 1 is provided with, in the outer end of filter frame, the claw 14 tiltedly stretching out and with outer rim 12 formation angle, Claw 14 is located at the intersection of outer rim 12.Interior frame 11 and outer rim 12 are bar shaped, and described claw 14 is taper.

The thickness of interior frame 11 and ring frame 13 is preferably smaller than the thickness of outer rim 12.

The interior frame 11 of framework 1, outer rim 12, ring frame 13 and claw 14 are formed in one, interior frame 11, outer rim 12 It is degradation material with ring frame 13 and claw 14 to make, preferably memory elasticity preferable PPDO or PCL material.

The Expected Results of the design product and value：Desired product will be degradable after 3 ~ June after implantation postcava, Need not perform the operation again taking-up, and now phlebothrombosises state of an illness after the active treatments such as anticoagulant is stable, without kish foreign body And anticoagulant throughout one's life.The operation of this class, in more than ten years of wide clinical application, is implanted quantity and is expected tens thousand of every year ~ hundreds thousand of examples, medical science And social value is huge.

The above, simply better embodiment of the present utility model, but this utility model is not limited to above-mentioned reality Apply example, as long as it reaches technique effect of the present utility model with any same or similar means, all should fall into of the present utility model Within protection domain.

Claims (10)

1. a kind of degradable vena cava filter, including three-dimensional filter frame it is characterised in that：Described filter frame is in infundibulate, filter Device frame is rotatably provided with several connected frameworks, and described framework includes the interior frame axially extending obliquely out along filter frame and being connected With outer rim, the tip being filter frame to interior frame one end that filter frame center extends, and framework are in the tip setting of filter frame Have connect interior frame ring frame, one end that described outer rim tiltedly stretches out be filter frame outer end, interior frame, outer rim and Ring frame is degradation material, and the thickness of interior frame and ring frame is less than or equal to the thickness of outer rim.

2. a kind of degradable vena cava filter according to claim 1 it is characterised in that：The end of every described interior frame Corresponding one end with two described outer rim of two neighboring framework connects altogether, and the other end of two outer rim is connected to filter frame Outer end, the thickness of interior frame and described ring frame is less than the thickness of outer rim.

3. a kind of degradable vena cava filter according to claim 1 it is characterised in that：Described interior frame arc is to filter Lateral bend in frame, described outer rim arc is to lateral bend outside filter frame.

4. a kind of degradable vena cava filter according to claim 1 it is characterised in that：Described framework is outer in filter frame End is provided with the claw tiltedly stretching out and forming angle with outer rim.

5. a kind of degradable vena cava filter according to claim 4 it is characterised in that：The interior frame of described framework, outer Frame, ring frame and claw are formed in one.

6. according to a kind of arbitrary described degradable vena cava filter of claim 1-5 it is characterised in that：Two often adjacent institutes State framework part to be crisscross arranged, two adjacent described outer rim intersect intersecting connection.

7. according to a kind of arbitrary described degradable vena cava filter of claim 1-5 it is characterised in that：The adjacent institute of each two State the filter frame outer end axially height setting straggly that outer rim stretches out.

8. according to a kind of arbitrary described degradable vena cava filter of claim 1-5 it is characterised in that：Described filter frame also sets It is equipped with the absorbable silk thread through described framework, described absorbable silk thread constitutes filter mesh with framework, and absorbable silk thread is can Degraded material.

9. a kind of degradable vena cava filter according to claim 8 it is characterised in that：Described absorbable silk thread ring respectively Form interior loop and/or exterior loop around the described interior frame of connection and outer rim.

10. a kind of degradable vena cava filter according to claim 8 it is characterised in that：Described absorbable silk thread also connects Connect the outer end of filter frame and most advanced and sophisticated ring frame forms separator bar.