A kind of can quickly self-cleaning animal aerosol expose experimental system
Technical field
This utility model belongs to suction characteristics research field, be specifically related to a kind of can the animal aerosol exposure system of quick self-cleaning.
Background technology
Along with the research that Inhalation is tested by the toxicologic development such as international environment, health, medical science and increasing research institution.Various Inhalation experimental facilitiess emerge in an endless stream.China is also stepping up to research and develop the related experiment equipment in this field.Inhalation one word comes from English " Inhalation ", and this word only refers to contaminate through the exposure of mouth and nose, many with Inhalation general designation contamination technology in the world.But as far as the principle of experiment, mode etc., we term it expose contamination (exposure).
Animal exposes the development of experimental facilities and needs the factors such as the recycling according to the parameter monitored required in laboratory animal kind and number, contamination material physicochemical property, contaminating mode, contamination process and contamination material or processing mode, for the special installation that specific requirement of experiment customizes.Equipment also to ensure the safety of personnel and environment in experimentation while ensureing the convenience of experimental implementation.The classification of contamination equipment, as according to naked position and mode, being divided into: systemic exposure contamination equipment;Mouth and nose suck and expose contamination equipment;Isolated cells exposes contamination equipment;Different types of contamination equipment, if according to its system composition almost has again same or similar construction unit, e.g., system dynamic unit air air compressor;Contamination material feed unit generator;Contamination material exposes contamination unit exposure compartment;Contamination process environment Monitoring and Controlling unit monitoring means;Sample analysis sampling unit and contamination material recycling unit etc..
The animal mouth and nose Inhalation exposure system that this utility model relates to be the mouth and nose of animal are exposed to contamination material environment under.Laboratory animal is placed in a special animal support, and animal support is fixed in exposure compartment, and forms good air inlet waste gas autonomous channel with cabin, realizes the exposure exposure experiment to animal by controlling the material concentration in exposure compartment.Animal mouth and nose Inhalation exposure system can be widely applied to medicine, chemicals, chemistry security evaluation field, inhalational immunization field, animal breath Disease model and effect experiment field, environmental evaluation field, radioactive substance hazard evaluation and protection field, military medicine, aerospace medicine field.Existing exposure system is primarily present following defect: one be spraying after aerosol be not easy to be diffused into whole exposure compartment;Two is discharged the contamination aerosol in exposure compartment after exposure has been tested to take long enough, after experiment terminates, namely experimenter opens isolating seal cabin and exposure compartment and laboratory animal is taken out, contamination aerosol leaks to operating room, experimenter need to be equipped with protective gear, animal is taken out, closing chamber behind the door, in the cabin in and the contamination aerosol of operating room pass slowly the filter of filter system more only.
Utility model content
This utility model is for the deficiencies in the prior art, it is provided that a kind of automatization animal aerosol exposes experimental system, can quickly self-cleaning after completing to expose experiment, it is to avoid aerosol is excessive causes environmental pollution, endanger experimenter's safety.
A kind of can quickly self-cleaning animal aerosol expose experimental system, this system includes: aerosol generating unit, sampling of aerosol unit, isolating seal cabin, self-cleaning gas circulation unit and negative pressure protected location;Arranging exposure compartment in described isolating seal cabin, described aerosol generating unit, sampling of aerosol unit and self-cleaning gas circulation unit connect exposure compartment respectively, and described negative pressure protected location connects isolating seal cabin.
Described isolating seal cabin supports for providing the installation of an airtight protective environment and miscellaneous part for exposing experiment;Described exposure compartment provides hybird environment for the contamination aerosol exposing experiment for animal aerosol, and prevents leakage of aerosol.
Further, self-cleaning gas circulation unit includes: self-cleaning blower fan, top filter, circulation QI invigorating filter, described circulation QI invigorating filter by gram in sum generator connection exposure compartment bottom, exposure compartment top is sequentially connected with water-separating gas filter, top filter, effusion meter, self-cleaning blower fan.
Described circulation QI invigorating high efficiency particulate air filter is entered the surrounding air of exposure compartment for filtering by external environment;In described gram, sum generator is for contaminating the atomization of material such as medicine, bacterium solution etc., aerocolloidal formation;Described water-separating gas filter, for getting rid of the moisture content in sample gas, protects follow-up gas path component;Described top filter is for filtering out the contamination material extracted out in aerosol in self-cleaning gas circuit;Described effusion meter is for measuring flow and the pressure of self-cleaning gas circuit.
Further, circulation QI invigorating filter is bellows high efficiency particulate air filter.
Further, self-cleaning blower fan is plain shaft flow fan, and flow is controlled, and more than 0.3 μm particle filtration efficiency is 99.99% by top filter and circulation QI invigorating filter.
Further, negative pressure protected location includes: negative-pressure air fan, exhaust-air filter, and the end of bleeding of described negative-pressure air fan connects isolating seal cabin, and the exhaust outlet of negative-pressure air fan connects exhaust-air filter, and exhaust-air filter is connected to isolating seal out of my cabin.
Described exhaust-air filter is for filtering filtration before complete machine aerofluxus, it is ensured that the gas of self-cleaning and negative pressure system discharge after filtering will not environment to external world;Described negative-pressure air fan is for for providing subnormal ambient in isolating seal cabin, it is ensured that do not have gas in cabin and leak out.
Further, exhaust-air filter is board-like high efficiency particulate air filter, is 99.99% to more than 0.3 μm particle filtration efficiency.
Further, in isolating seal cabin, pressure is 50-200Pa.
Further, in isolating seal cabin, it is provided with pressure transducer and decompression alarm lamp, detects and warning when negative pressure is too low, can be started.
Further, placement operation glove in isolating seal cabin, it is possible to do not contact experiment equipment in internal medium operational window, one is will not experiment be had undesirable effect, and two is operator to be played protective action.
Further, isolating seal cabin inner top is equipped with optical hydrogen ion disinfector and LED illumination lamp.Antibacterial in isolating seal cabin can be carried out sterilization processing by optical hydrogen ion disinfector, protects personal security.
Further, isolating seal cabin is front and back double swing doors, adopts double-layer box body protection structure, and inner bag is that 316 rustless steels seal welding fabrication, and outer layer is cold-rolled steel sheet plastic-blasting.Isolating seal cabin has good seal, it is ensured that have certain negative pressure in cabinet.Owing to the operating surface degree of depth in isolating seal cabin is relatively deep, 1.2 meters can be reached, not easily operate, therefore have employed the design of gull wing type double door, user-friendly.
Further, installing silencing means after exhaust-air filter, after exhaust-air filter noise reduction, gas is through silencing means, and noise is further reduced.
This utility model provides a kind of safe and reliable animal and exposes exposure experiment shielding system, and compared to prior art, its advantage essentially consists in:
1. constantly being discharged after the aerosol filtration within exposure compartment by self-cleaning blower fan in whole experimentation, poisonous gas of will not having illicit sexual relations is discharged and is ensured experimenter's safety;Contamination aerosol in exposure compartment has been at, in a dynamic process, being conducive to aerocolloidal diffusion;Carry out gas by two, bottom circulation QI invigorating filter to supplement so that the air pressure in exposure compartment and atmospheric pressure balance simultaneously.
2. after aerosol spray terminates, namely exposure experiment completes, keep self-cleaning gas circulation unit to open and carry out lasting self-cleaning, until contamination material concentration is 0.Quickly the contamination aerosol filtration in exposure compartment can be discharged by pinpointing self-cleaning, but not spontaneous diffusion of the prior art, therefore the cleaning time used is shorter, and it is more thorough, open hatch door when determining nontoxic residual in exposure compartment and take out laboratory animal, do not result in infection gas leak and cause environmental pollution, harm personal safety.Clean-down capability can also obtain an empirical value by experiment, the acquisition methods of empirical value is: the aerosol after contamination is sampled after self-cleaning a period of time again, contamination material concentration after sampling is the shortest time 0 this time being self-cleaning, test can directly empirically be worth after terminating later every time and carry out self-cleaning, it is possible on the basis of empirical value, be further added by a period of time to increase safety factor.
3. whole experimental system has perfect negative pressure insulation blocking system, can realize negative pressure protection from start, and have decompression warning function, effectively prevent experimenter to be infected.
Accompanying drawing explanation
Fig. 1 isolating seal cabin sectional view;
A-A face, Fig. 2 isolating seal cabin sectional view;
Fig. 3 self-cleaning system gas circuit connects figure.
In figure: 1-isolating seal cabin;2-exposure compartment;3-circulates QI invigorating filter;Sum generator in 4-gram;5-water-separating gas filter;6-top filter;7-effusion meter;8-self-cleaning blower fan;9-exhaust-air filter;10-negative-pressure air fan;11-silencing means.
Detailed description of the invention
Below in conjunction with specific embodiment and accompanying drawing, this utility model is described in further details.
A kind of can quickly self-cleaning animal aerosol expose experimental system, this system includes: aerosol generating unit, sampling of aerosol unit, isolating seal cabin, self-cleaning gas circulation unit and negative pressure protected location.As it is shown in figure 1, arrange exposure compartment 2 in isolating seal cabin 1, aerosol generating unit, sampling of aerosol unit and self-cleaning gas circulation unit connect exposure compartment 2 respectively, and negative pressure protected location connects isolating seal cabin 1.
Self-cleaning gas circulation unit as shown in Figure 3, including: self-cleaning blower fan 8, top filter 6, circulation QI invigorating filter 3, circulation QI invigorating filter 3 by gram in sum generator 4 connect bottom exposure compartment 2, exposure compartment 2 top is sequentially connected with water-separating gas filter 5, top filter 6, effusion meter 7, self-cleaning blower fan 8.
Circulation QI invigorating filter 3 is bellows high efficiency particulate air filter.
Self-cleaning blower fan 8 is plain shaft flow fan, and flow is controlled, and more than 0.3 μm particle filtration efficiency is 99.99% by top filter 6 and circulation QI invigorating filter 3.
Negative pressure protected location as shown in Figure 2; including: negative-pressure air fan 10, exhaust-air filter 9; the end of bleeding of negative-pressure air fan 10 connects isolating seal cabin 1; the exhaust outlet of negative-pressure air fan 10 connects exhaust-air filter 9; exhaust-air filter 9 joint noise reduction device 11; silencing means 11 is communicated to isolating seal out of my cabin, and gas is exhausted directly to out of my cabin after filtration, denoising.
Exhaust-air filter 9 is board-like high efficiency particulate air filter.
In isolating seal cabin 1, pressure is 50-200Pa, inside sets pressure transducer and decompression alarm lamp, detects and can start warning when negative pressure is too low;Top is equipped with optical hydrogen ion disinfector and LED illumination lamp.
Placement operation glove in isolating seal cabin 1, it is possible to do not contact experiment equipment in internal medium operational window.
Isolating seal cabin 1 is front and back double swing doors, adopts double-layer box body protection structure, and inner bag is that 316 rustless steels seal welding fabrication, and outer layer is cold-rolled steel sheet plastic-blasting.Isolating seal cabin 1 has good seal, it is ensured that have certain negative pressure in cabinet.Owing to the operating surface degree of depth in isolating seal cabin 1 is relatively deep, 1.2 meters can be reached, not easily operate, therefore have employed the design of gull wing type double door, user-friendly.
The workflow of said system is as follows:
After self-cleaning gas circulation unit starts, gas sequentially passes through water-separating gas filter 5 after circulation QI invigorating filter 3 QI invigorating enters exposure compartment 2 and dewaters, and top filter 6 filters, and discharges through self-cleaning blower fan 8 after effusion meter 7 metering.When the spraying startup of aerosol generating unit, namely self-cleaning gas circulation unit starts working, after spraying terminates, according to setting self-cleaning a period of time time, and the nontoxic rear stopping of air cleaning in cabin 2 to be exposed.
Negative pressure protected location is omnidistance in the self purification process after aerosol exposure test process and spraying terminate to be opened, and keeping in isolating seal cabin 1 is subnormal ambient.The operation principle in negative pressure isolating seal cabin 1 is: negative-pressure air fan 10 is by constantly bleeding, isolating seal cabin 1 internal gas pressure is reduced, in experimentation, the negative pressure in isolating seal cabin 1 should within 50~200Pa, the contamination substance escaping of 1 in negative pressure isolating seal cabin so will not be made in external environment, experimenter to be polluted.Negative-pressure air fan 10 expellant gas is through exhaust-air filter 9 simultaneously, after silencing means 11 noise reduction, discharged to air.