CN205099686U - Production of plasma protein polypeptide is with broken system of blood cell - Google Patents

Production of plasma protein polypeptide is with broken system of blood cell Download PDF

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Publication number
CN205099686U
CN205099686U CN201520863016.5U CN201520863016U CN205099686U CN 205099686 U CN205099686 U CN 205099686U CN 201520863016 U CN201520863016 U CN 201520863016U CN 205099686 U CN205099686 U CN 205099686U
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China
Prior art keywords
blood cell
level
shredder assembly
crushing device
level shredder
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Expired - Fee Related
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CN201520863016.5U
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Chinese (zh)
Inventor
郝刚
安永斌
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CHENGDU HONGAN BIOTECHNOLOGY Co Ltd
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CHENGDU HONGAN BIOTECHNOLOGY Co Ltd
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Abstract

The utility model relates to a production of plasma protein polypeptide is with broken system of blood cell, connect gradually blood cell bin, blood cell enrichment facility, one -level breaker and second grade breaker including top -down, the blood cell enrichment facility is the gradient centrifugation machine, and the lateral wall is provided with the supernatant collecting pit on the blood cell enrichment facility, one -level breaker lateral wall is provided with the ultrasonic crashing appearance, and the inside level that is provided with of one -level breaker stirs the pivot, and level stirring pivot left side is provided with and is used for drive level stirring pivot pivoted driving motor, sets up vertical stirring leaf oar in the level stirring pivot, and the level that sets up on the vertical stirring leaf oar stirs the leaf oar, and vertical stirring leaf oar is mutually perpendicular with level stirring leaf oar. The utility model provides high blood cell percentage of damage has further improved the extraction percentage of plasma protein polypeptide.

Description

A kind of plasma proteins polypeptide is produced and is used blood cell crushing system
Technical field
The utility model relates to plasma proteins technical field of polypeptide, particularly a kind of plasma proteins polypeptide production blood cell crushing system.
Background technology
Plasma proteins polypeptide can be widely used in the fields such as feed, medicine, healthcare products, food, has high added value, and nutritive ingredient abundant in blood and numerous active substance with biological function are fully utilized.Plasma proteins polypeptide is as a kind of material of high nutritive value, its resource seems very valuable, therefore, when utilizing blood cell to carry out the extraction of plasma proteins polypeptide, to greatest extent that blood cell is broken, be the more abundant of the plasma proteins polypeptide release in blood cell, improve the extraction yield of plasma proteins polypeptide, seem particularly important.Existing plasma proteins polypeptide production technique, carries out fragmentation mainly through stirring action to blood cell, this kind of design, and blood cell percentage of damage ground, causes the extraction yield of plasma proteins polypeptide low.
Based on above analysis, technological improvement is carried out to existing plasma proteins polypeptide production blood cell shredder assembly, design a kind of plasma proteins polypeptide production blood cell crushing system, improve blood cell percentage of damage, improve the extraction yield of plasma proteins polypeptide.
Utility model content
The purpose of this utility model is, technological improvement is carried out for existing plasma proteins polypeptide production blood cell shredder assembly Problems existing, design a kind of plasma proteins polypeptide production blood cell crushing system, improve blood cell percentage of damage, improve the extraction yield of plasma proteins polypeptide.
The utility model is achieved through the following technical solutions:
A kind of plasma proteins polypeptide is produced and is used blood cell crushing system, it is characterized in that, structure comprises and connects blood cell bin (1), blood cell concentrating unit (2), one-level shredder assembly (3) and two-stage crushing device (4) successively from top to bottom;
Described blood cell concentrating unit (2) is Gradient Centrifuge, and blood cell concentrating unit (2) upper side wall is provided with supernatant collection pond (21);
Described one-level shredder assembly (3) sidewall is provided with sonicator (31), one-level shredder assembly (3) inside is provided with horizontal stirring shaft (32), horizontal stirring shaft (32) left side is provided with the drive-motor (33) for driving horizontal stirring shaft (32) to rotate, horizontal stirring shaft (32) is arranged vertical paddle oar (34), vertical paddle oar (34) arranges horizontal paddle oar (35), and vertical paddle oar (34) is perpendicular with horizontal paddle oar (35);
Described one-level shredder assembly (3) left side wall arranges the water tank (5) be communicated with one-level shredder assembly (3);
Described two-stage crushing device (4) left side wall arranges proteolytic enzyme liquid-storing box (6), and two-stage crushing device (4) bottom arranges heating jacket (41);
Connecting pipeline between described blood cell bin (1) and blood cell concentrating unit (2) is provided with the first trip switch valve (11);
Connecting pipeline between described blood cell concentrating unit (2) and one-level shredder assembly (3) is provided with the second trip switch valve (22);
Connecting pipeline between described one-level shredder assembly (3) and two-stage crushing device (4) is provided with the 3rd trip switch valve (36);
Connecting pipeline between described water tank (5) and one-level shredder assembly (3) is provided with the 4th trip switch valve (51).
Further, described two-stage crushing device (4) right side wall arranges liquid-outlet valve (42).
Further, the connecting pipeline between described proteolytic enzyme liquid-storing box (6) and two-stage crushing device (4) is provided with the 5th trip switch valve (61).
The utility model provides a kind of plasma proteins polypeptide production blood cell crushing system, and compared with prior art, beneficial effect is:
1, the plasma proteins polypeptide of the utility model design is produced and is used blood cell crushing system, connect blood cell bin (1) successively from top to bottom, blood cell concentrating unit (2), one-level shredder assembly (3) and two-stage crushing device (4), wherein one-level shredder assembly (3) mechanical disruption device that is physically based deformation, two-stage crushing device (4) is the snowball shredder assembly based on biological enzymolysis, this kind of project organization, mechanical disruption device and biological enzymolysis shredder assembly are integrated in one, greatly improve the crushing efficiency of blood cell, then ensure that raw material extracts the extraction yield of plasma proteins polypeptide based on blood cell.
2, the plasma proteins polypeptide of the utility model design is produced and is used blood cell crushing system, one-level shredder assembly (3) sidewall is provided with sonicator (31), one-level shredder assembly (3) inside is provided with horizontal stirring shaft (32), horizontal stirring shaft (32) left side is provided with the drive-motor (33) for driving horizontal stirring shaft (32) to rotate, horizontal stirring shaft (32) is arranged vertical paddle oar (34), vertical paddle oar (34) arranges horizontal paddle oar (35), vertical paddle oar (34) is perpendicular with horizontal paddle oar (35), one-level shredder assembly (3) left side wall arranges the water tank (5) be communicated with one-level shredder assembly (3), this kind of project organization, utilize the liquid water that water tank (5) is carried, blood cell is made to continue water suction, blood cell increases, and is easy to break, the impact force utilizing horizontal stirring shaft (32) and the vertical paddle oar (34) coordinated with it and horizontal paddle oar (35) to increase demand and shock probability, promote percentage of damage, meanwhile, produce ultrasonic wave by sonicator (31) and depth crushing is carried out to pending blood cell, improve percentage of damage equally.
3, the plasma proteins polypeptide of the utility model design is produced and is used blood cell crushing system, increase and have two-stage crushing device (4), two-stage crushing device (4) left side wall arranges proteolytic enzyme liquid-storing box (6), two-stage crushing device (4) bottom arranges heating jacket (41), this kind of project organization, the proteolytic enzyme utilizing proteolytic enzyme liquid-storing box (6) to export cracks further to blood cell, utilize heating jacket (41) to heat two-stage crushing device (4) simultaneously, the temperature in two-stage crushing device (4) is made to be easier to the activity excitation of proteolytic enzyme, the enzymolysis of proteolytic enzyme is utilized to carry out micro-fragmentation to blood cell, reach the object promoting crushing efficiency equally.
4, the plasma proteins polypeptide of the utility model design is produced and is used blood cell crushing system, increase and have blood cell concentrating unit (2), this kind of project organization, effectively remove the supernatant liquor in blood cell, for blood cell absorbs water fast in one-level shredder assembly (3), realize fragmentation and lay a good foundation.
Accompanying drawing explanation
Fig. 1 is the structural representation of the utility model plasma proteins polypeptide production blood cell crushing system.
Embodiment
Accompanying drawings 1 pair of the utility model is described further.
The utility model relates to a kind of plasma proteins polypeptide production blood cell crushing system, it is characterized in that, structure comprises and connects blood cell bin (1), blood cell concentrating unit (2), one-level shredder assembly (3) and two-stage crushing device (4) successively from top to bottom;
Described blood cell concentrating unit (2) is Gradient Centrifuge, and blood cell concentrating unit (2) upper side wall is provided with supernatant collection pond (21);
Described one-level shredder assembly (3) sidewall is provided with sonicator (31), one-level shredder assembly (3) inside is provided with horizontal stirring shaft (32), horizontal stirring shaft (32) left side is provided with the drive-motor (33) for driving horizontal stirring shaft (32) to rotate, horizontal stirring shaft (32) is arranged vertical paddle oar (34), vertical paddle oar (34) arranges horizontal paddle oar (35), and vertical paddle oar (34) is perpendicular with horizontal paddle oar (35);
Described one-level shredder assembly (3) left side wall arranges the water tank (5) be communicated with one-level shredder assembly (3);
Described two-stage crushing device (4) left side wall arranges proteolytic enzyme liquid-storing box (6), and two-stage crushing device (4) bottom arranges heating jacket (41);
Connecting pipeline between described blood cell bin (1) and blood cell concentrating unit (2) is provided with the first trip switch valve (11);
Connecting pipeline between described blood cell concentrating unit (2) and one-level shredder assembly (3) is provided with the second trip switch valve (22);
Connecting pipeline between described one-level shredder assembly (3) and two-stage crushing device (4) is provided with the 3rd trip switch valve (36);
Connecting pipeline between described water tank (5) and one-level shredder assembly (3) is provided with the 4th trip switch valve (51).
Preferably, as improvement, described two-stage crushing device (4) right side wall arranges liquid-outlet valve (42).
Preferably, as improvement, the connecting pipeline between described proteolytic enzyme liquid-storing box (6) and two-stage crushing device (4) is provided with the 5th trip switch valve (61).
Compared with prior art, the plasma proteins polypeptide of the utility model design is produced and is used blood cell crushing system, connect blood cell bin (1) successively from top to bottom, blood cell concentrating unit (2), one-level shredder assembly (3) and two-stage crushing device (4), wherein one-level shredder assembly (3) mechanical disruption device that is physically based deformation, two-stage crushing device (4) is the snowball shredder assembly based on biological enzymolysis, this kind of project organization, mechanical disruption device and biological enzymolysis shredder assembly are integrated in one, greatly improve the crushing efficiency of blood cell, then ensure that raw material extracts the extraction yield of plasma proteins polypeptide based on blood cell.
The plasma proteins polypeptide of the utility model design is produced and is used blood cell crushing system, one-level shredder assembly (3) sidewall is provided with sonicator (31), one-level shredder assembly (3) inside is provided with horizontal stirring shaft (32), horizontal stirring shaft (32) left side is provided with the drive-motor (33) for driving horizontal stirring shaft (32) to rotate, horizontal stirring shaft (32) is arranged vertical paddle oar (34), vertical paddle oar (34) arranges horizontal paddle oar (35), vertical paddle oar (34) is perpendicular with horizontal paddle oar (35), one-level shredder assembly (3) left side wall arranges the water tank (5) be communicated with one-level shredder assembly (3), this kind of project organization, utilize the liquid water that water tank (5) is carried, blood cell is made to continue water suction, blood cell increases, and is easy to break, the impact force utilizing horizontal stirring shaft (32) and the vertical paddle oar (34) coordinated with it and horizontal paddle oar (35) to increase demand and shock probability, promote percentage of damage, meanwhile, produce ultrasonic wave by sonicator (31) and depth crushing is carried out to pending blood cell, improve percentage of damage equally.
The plasma proteins polypeptide of the utility model design is produced and is used blood cell crushing system, increase and have two-stage crushing device (4), two-stage crushing device (4) left side wall arranges proteolytic enzyme liquid-storing box (6), two-stage crushing device (4) bottom arranges heating jacket (41), this kind of project organization, the proteolytic enzyme utilizing proteolytic enzyme liquid-storing box (6) to export cracks further to blood cell, utilize heating jacket (41) to heat two-stage crushing device (4) simultaneously, the temperature in two-stage crushing device (4) is made to be easier to the activity excitation of proteolytic enzyme, the enzymolysis of proteolytic enzyme is utilized to carry out micro-fragmentation to blood cell, reach the object promoting crushing efficiency equally.
The plasma proteins polypeptide of the utility model design is produced and is used blood cell crushing system, increase and have blood cell concentrating unit (2), this kind of project organization, effectively remove the supernatant liquor in blood cell, for blood cell absorbs water fast in one-level shredder assembly (3), realize fragmentation and lay a good foundation.
The utility model in use, the blood cell being stored in blood cell bin (1) completes fragmentation via blood cell concentrating unit (2), one-level shredder assembly (3) and two-stage crushing device (4) successively via connecting pipeline, finally exported by liquid-outlet valve (42), enter plasma proteins polypeptide essence and mention purifying process.
As described above, can apply the utility model.
The above; be only the utility model preferably embodiment; but protection domain of the present utility model is not limited thereto; anyly be familiar with those skilled in the art in the technical scope that the utility model discloses; be equal to according to the technical solution of the utility model and utility model design thereof and replace or change, all should be encompassed within protection domain of the present utility model.

Claims (3)

1. plasma proteins polypeptide is produced and is used a blood cell crushing system, it is characterized in that, structure comprises and connects blood cell bin (1), blood cell concentrating unit (2), one-level shredder assembly (3) and two-stage crushing device (4) successively from top to bottom;
Described blood cell concentrating unit (2) is Gradient Centrifuge, and blood cell concentrating unit (2) upper side wall is provided with supernatant collection pond (21);
Described one-level shredder assembly (3) sidewall is provided with sonicator (31), one-level shredder assembly (3) inside is provided with horizontal stirring shaft (32), horizontal stirring shaft (32) left side is provided with the drive-motor (33) for driving horizontal stirring shaft (32) to rotate, horizontal stirring shaft (32) is arranged vertical paddle oar (34), vertical paddle oar (34) arranges horizontal paddle oar (35), and vertical paddle oar (34) is perpendicular with horizontal paddle oar (35);
Described one-level shredder assembly (3) left side wall arranges the water tank (5) be communicated with one-level shredder assembly (3);
Described two-stage crushing device (4) left side wall arranges proteolytic enzyme liquid-storing box (6), and two-stage crushing device (4) bottom arranges heating jacket (41);
Connecting pipeline between described blood cell bin (1) and blood cell concentrating unit (2) is provided with the first trip switch valve (11);
Connecting pipeline between described blood cell concentrating unit (2) and one-level shredder assembly (3) is provided with the second trip switch valve (22);
Connecting pipeline between described one-level shredder assembly (3) and two-stage crushing device (4) is provided with the 3rd trip switch valve (36);
Connecting pipeline between described water tank (5) and one-level shredder assembly (3) is provided with the 4th trip switch valve (51).
2. plasma proteins polypeptide production blood cell crushing system according to claim 1, is characterized in that, described two-stage crushing device (4) right side wall arranges liquid-outlet valve (42).
3. plasma proteins polypeptide production blood cell crushing system according to claim 1, is characterized in that, the connecting pipeline between described proteolytic enzyme liquid-storing box (6) and two-stage crushing device (4) is provided with the 5th trip switch valve (61).
CN201520863016.5U 2015-11-03 2015-11-03 Production of plasma protein polypeptide is with broken system of blood cell Expired - Fee Related CN205099686U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201520863016.5U CN205099686U (en) 2015-11-03 2015-11-03 Production of plasma protein polypeptide is with broken system of blood cell

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201520863016.5U CN205099686U (en) 2015-11-03 2015-11-03 Production of plasma protein polypeptide is with broken system of blood cell

Publications (1)

Publication Number Publication Date
CN205099686U true CN205099686U (en) 2016-03-23

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201520863016.5U Expired - Fee Related CN205099686U (en) 2015-11-03 2015-11-03 Production of plasma protein polypeptide is with broken system of blood cell

Country Status (1)

Country Link
CN (1) CN205099686U (en)

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20160323

Termination date: 20161103