CN205072904U - Composite set is gathered to vacuum saliva - Google Patents

Abstract

The utility model relates to a saliva collection device, in particular to a vacuum saliva collection combination device, which includes a saliva storage part and a saliva collection part. At the mouth of the tube, the protective cap is wrapped outside the rubber plug, and wraps the mouth of the original tube, and is evacuated, and the stabilizer is set in the original tube; the saliva collection part is composed of a collection tube and a puncture needle, and the end of the collection tube is set There is a connection port, the inner end of the connection port is provided with a filter, and the end of the puncture needle is provided with a connection cap, and the collection tube and the puncture needle are connected together through the connection port and the connection cap. The utility model has the following advantages: closed collection of saliva, avoiding the interference of environmental microorganisms; unnecessary microorganisms and food residues in the saliva can be filtered to make the results more accurate; simple components, easy to operate; vacuum negative pressure, saliva collection is smoother; preset The stabilizer can stabilize the detection substance, without adding additional stabilizer and reducing the operation steps.

Description

Vacuum saliva collection combination device

technical field

The utility model relates to a saliva collection device, in particular to a vacuum saliva collection combination device.

Background technique

Saliva is a colorless and thin liquid secreted by glands in the oral cavity. Its main components are protein and water, and it also contains cells exfoliated in the oral cavity, biomacromolecules and microorganisms, such as oral mucosal cells, fatty acids, bacteria, viruses, DNA and RNA etc. Through the detection of saliva, it is beneficial to the early diagnosis and early treatment of diseases. The detection of saliva is not only used for the diagnosis of oral diseases, but also for the diagnosis of various diseases such as cancer, diabetes, and genetic diseases. are receiving increasing clinical attention. The detection of saliva must first collect and store saliva, but the existing saliva collection devices have defects such as inconvenient operation, difficult collection, easy contamination, and inconsistent sampling volume, which bring great troubles to clinical testing.

Contents of the invention

The purpose of this utility model is to invent a vacuum saliva collection combination device preset with a stabilizer in order to overcome the defects of the existing saliva collection device such as inconvenient operation and difficult collection.

The purpose of this utility model is achieved in the following manner: the vacuum saliva collection combination device includes a saliva storage part and a saliva collection part, the saliva storage part is composed of an original tube, a rubber plug, a protective cap, a stabilizer, and the rubber plug Plug in the mouth of the original tube, the original tube is evacuated, the protective cap is wrapped outside the rubber plug, and the stabilizer is set in the original tube; the saliva collection part is composed of a collection cup, a collection chamber and a puncture needle, and one end of the collection chamber is connected to the collection cup. The other end of the collection chamber is provided with a needle-fixing boss, and one end of the puncture needle is provided with a needle seat, and the collection chamber and the puncture needle are connected together through the needle-fixing boss and the needle seat; the inner end of the collection chamber is provided with a filter, The puncture needle is provided with a liquid-blocking sleeve outside, and the liquid-blocking sleeve is provided with a sheath outside.

Described stabilizing agent, different according to clinical detection content, it comprises following composition: when being used for oral cavity exfoliated cell detection, its composition is cytoprotective agent, as trehalose, dimethyl sulfoxide; For saliva free nucleic acid (DNA and RNA ) detection, its composition is a nucleic acid stabilizer, such as imidazolidinyl urea, purine, pyrimidine; when used for protein and enzyme detection, its composition is a protein stabilizer, such as aprotinin; when used for virus detection, its composition It is a virus preservation solution, such as HANK'S solution; when it is used for bacterial detection, its composition is a bacteria preservation solution, such as bacterial culture medium water preparation.

The original tube of the saliva storage part is a round bottom test tube, a pointed bottom test tube or a bottle.

The original pipe is connected with the protective cap through the outer helix on the mouth of the original pipe and the inner helix of the protective cap.

The original pipe and the rubber plug are directly plugged and fitted.

The rubber stopper can be replaced by an aluminum-plastic film.

The needle-fixing boss of the collection chamber is in the shape of an internal thread tube, the needle seat of the puncture needle is in the shape of an external thread tube, and the collection chamber and the puncture needle are screwed together through the needle-fixing boss and the needle seat.

The needle-fixing boss of the collection chamber and the needle seat of the puncture needle are both tapered, and the collection chamber and the puncture needle are inserted into one body through the needle-fixing boss and the needle seat.

The sheath is connected to the collection cavity, and the puncture needle and the liquid blocking sheath are included in the sheath.

The original tube is made of glass or plastic material, preferably PET; the protective cap is made of plastic material, such as PE, PP or a combination of PE and PP; the collection cup, collection cavity, and needle-fixing boss are made of plastic; The puncture needle is made of stainless steel or hard plastic, preferably stainless steel; the liquid-resistant sleeve is made of rubber; the sheath is made of plastic.

The positive effects of the utility model are as follows: 1. The closed collection of saliva avoids the interference of environmental microorganisms. 2. It can filter unwanted microorganisms and food residues in saliva to make the results more accurate. 3. The components are simple and easy to operate. 4. Vacuum negative pressure, saliva collection is smoother. 5. The preset stabilizer can stabilize the detection substance, no need to add additional stabilizer, and reduce the operation steps. 6. The liquid-blocking sleeve is placed outside the puncture needle to prevent saliva from leaking out.

Description of drawings

Fig. 1 is a structural diagram of saliva storage embodiment one

Fig. 2 is the structural diagram of the second embodiment of saliva storage

Fig. 3 is a structural diagram of saliva collection embodiment one

Fig. 4 is the structural diagram of the second embodiment of saliva collection

Fig. 5 is the structural diagram of the third embodiment of saliva collection

In the picture: 1 original tube 2 rubber plug 3 protective cap

4 stabilizer 5 collection cavity 6 puncture needle

7 fixed needle boss 8 needle seat 9 outer spiral

10 internal spiral 11 filter piece 12 collection cup

13 liquid resistance sleeve 14 sheath

detailed description

As shown in Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5, the vacuum saliva collection combination device includes a saliva storage part and a saliva collection part, and the saliva storage part consists of an original tube 1, a rubber plug 2, a protective cap 3, and a stabilizer 4. The rubber stopper 2 is plugged in the mouth of the original tube 1, the original tube 1 is evacuated, the protective cap 3 is wrapped on the outside of the rubber plug 2, and the stabilizer 4 is arranged in the original tube 1; the saliva collection part is collected by the collection cup 12, The cavity 5 and the puncture needle 6 are composed of one end of the collection cavity 5 connected to the collection cup 12, the other end of the collection cavity 5 is provided with a needle-fixing boss 7, one end of the puncture needle 6 is provided with a needle base 8, the collection cavity 5 and the puncture The needle 6 is integrated with the needle holder 8 through the needle-fixing boss 7; a filter 11 is provided at the inner end of the collection chamber 5, a liquid-blocking sleeve 13 is provided outside the puncture needle 6, and a sheath 14 is provided outside the liquid-blocking sleeve.

Described stabilizer 4, differs according to clinical detection content, and it comprises following composition: when being used for oral exfoliated cell detection, its composition is cytoprotective agent, as trehalose, dimethyl sulfoxide; For saliva free nucleic acid (DNA and When detecting RNA), its composition is a nucleic acid stabilizer, such as imidazolidinyl urea, purine, pyrimidine; when used for protein and enzyme detection, its composition is a protein stabilizer, such as aprotinin; when used for virus detection, its The composition is a virus preservation solution, such as HANK'S solution; when used for bacterial detection, its composition is a bacteria preservation solution, such as a bacterial culture medium water preparation.

The original tube 1 is a round bottom test tube, a pointed bottom test tube or a bottle (see Figure 1).

The original pipe 1 is connected with the protective cap 3 through the outer helix 9 on the mouth of the original pipe 1 and the inner helix 10 of the protective cap (see FIG. 1 ).

The original pipe 1 and the rubber plug 2 are directly plugged and fitted (see FIG. 2 ).

The rubber plug 2 can be replaced by an aluminum-plastic film.

The needle-fixing boss 7 of the collection chamber 5 is internally threaded, the needle seat 8 of the puncture needle 6 is externally threaded, and the collection chamber 5 and the puncture needle 6 are screwed together through the needle-fixing boss 7 and the needle seat 8 ( See Figure 4).

The needle-fixing boss 7 of the collection chamber 5 and the needle seat 8 of the puncture needle 6 are both tapered, and the collection chamber 5 and the puncture needle 6 are inserted into one body through the needle-fixing boss 7 and the needle seat 8 (see Figure 5) .

The sheath 14 is connected to the collection cavity 5, and the puncture needle 6 and the liquid-blocking sheath 13 are included in the sheath 14 (see FIG. 3 ).

The original tube 1 is made of glass or plastic material, preferably plastic is PET; protective cap 3 is made of plastic material, such as PE, PP or PE and PP composite material; collection cup 12, collection cavity 5, fixed needle boss 7 is made of plastic; the puncture needle 6 is made of stainless steel or hard plastic, preferably stainless steel; the liquid blocking sleeve 13 is made of rubber; the sheath 14 is made of plastic.

When in use, connect and fix the needle seat on the puncture needle with the needle-fixing boss on the collection chamber in advance, collect saliva through the collection cup, the saliva flows into the collection chamber, collect 2-10ml of saliva from the subject or patient in the collection chamber, and then use the puncture The needle pierces the rubber stopper on the original tube. Since the original tube is preset with a vacuum, the saliva in the collection chamber will be drawn into the original tube through the filter and mixed with the stabilizer in the original tube until the vacuum is exhausted. Then pull out the puncture needle, separate the saliva storage part from the saliva collection part, the rubber stopper is automatically closed, and then turn the saliva storage part back and forth 5-8 times to fully mix the saliva and the stabilizer, and the saliva sample collection is completed.

The connection mode of the saliva collection part in the vacuum saliva collection combination device described in this patent is expressed in the form of internal and external spiral connection, but it does not rule out that the connection mode of the saliva collection part can be changed to plastic parts that can be inserted, welded and bonded. Ways, that is, the connection of the collection cup, collection cavity and sheath of the saliva collection part can be connected not only by internal and external spirals, but also by plugging, welding and bonding, all of which belong to the expression scope of this patent.

Claims (11)

1. a vacuum saliva gathers combination unit, it is characterized in that: described vacuum saliva gathers combination unit, comprise saliva storage compartment and saliva collecting part, saliva storage compartment is made up of former pipe, plug, protective cap, stabilizing agent, plug plug is in the mouth of pipe of former pipe, former pipe is evacuated, and protective cap is wrapped in outside plug, and stabilizing agent is located in former pipe; Saliva collecting part is made up of acquisition cup, acquisition cavity and puncture needle, one end of acquisition cavity is connected with acquisition cup, the other end of acquisition cavity is provided with solid pin boss, and one end of puncture needle is provided with needle stand, and acquisition cavity and puncture needle are connected in one by solid pin boss and needle stand; Acquisition cavity the inner is provided with filter disc, and puncture needle outside is provided with liquid-blocking sleeve, is provided with sheath outside liquid-blocking sleeve.

2. vacuum saliva according to claim 1 gathers combination unit, it is characterized in that: described stabilizing agent, and different according to Clinical detection content, it comprises following composition: when detecting for mouth desquamated cells, it consists of cytoprotective; For saliva dissociate detection of nucleic acids time, it consists of nucleic acid stability agent; When detecting for protein and enzyme, it consists of protein stabiliser; During for Viral diagnosis, it consists of viral conserving liquid; During for Bacteria Detection, it consists of antibacterial conserving liquid.

3. vacuum saliva according to claim 2 gathers combination unit, it is characterized in that: described cytoprotective is trehalose, dimethyl sulfoxide; Described nucleic acid stability agent is imidazolidinyl urea, purine, pyrimidine; Described protein stabiliser is aprotinin; Described viral conserving liquid is HANK ' S liquid; Described antibacterial conserving liquid is bacteria culture media water formulation.

4. vacuum saliva according to claim 1 gathers combination unit, it is characterized in that: the former pipe of described saliva storage compartment is round bottom test tube, point end test tube or pitcher.

5. vacuum saliva according to claim 1 gathers combination unit, it is characterized in that: described former pipe is connected with the internal coiling of protective cap by the external spiral on the former pipe mouth of pipe with protective cap.

6. vacuum saliva according to claim 1 gathers combination unit, it is characterized in that: described former pipe and plug directly carry out grafting and coordinate.

7. vacuum saliva according to claim 1 gathers combination unit, it is characterized in that: described plug can substitute with aluminum plastic film.

8. vacuum saliva according to claim 1 gathers combination unit, and it is characterized in that: the solid pin boss of described acquisition cavity is female thread tubulose, the needle stand of puncture needle is external screw thread tubulose, and acquisition cavity and puncture needle are bolted in one by solid pin boss and needle stand.

9. vacuum saliva according to claim 1 gathers combination unit, it is characterized in that: the solid pin boss of described acquisition cavity and the needle stand of puncture needle are taper, and acquisition cavity and puncture needle are plugged in one by solid pin boss and needle stand.

10. vacuum saliva according to claim 1 gathers combination unit, it is characterized in that: described sheath is connected on acquisition cavity, puncture needle and liquid-blocking sleeve is included in sheath.

11. vacuum salivas according to claim 1 gather combination unit, it is characterized in that: described former pipe is made up of glass or plastic material; Protective cap is made up of plastic material; Acquisition cup, acquisition cavity, solid pin boss are plastic material; Puncture needle is stainless steel and rigid plastics material; Liquid-blocking sleeve is made up of elastomeric material; Sheath is plastic material.