CN205015354U - Reagent encapsulates micro -fluidic chip in advance and experiment appearance thereof - Google Patents
Reagent encapsulates micro -fluidic chip in advance and experiment appearance thereof Download PDFInfo
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- CN205015354U CN205015354U CN201520781171.2U CN201520781171U CN205015354U CN 205015354 U CN205015354 U CN 205015354U CN 201520781171 U CN201520781171 U CN 201520781171U CN 205015354 U CN205015354 U CN 205015354U
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Abstract
The utility model relates to a reagent encapsulates micro -fluidic chip, application method and experiment appearance and working method in advance, and this reagent encapsulates micro -fluidic chip in advance and adopts the multilayer setting, and top -down includes: reagent reserve liquid layer, intermediate junction layer, microchannel layer, mix the conversion zone, it will react reagent and encapsulate in advance in micro -fluidic chip, reduce operator's application of sample step.
Description
Technical field
The utility model relates to a kind of microfluidic art, particularly relates to the pre-packaged micro-fluidic chip of a kind of reagent and experiment instrument thereof.
Background technology
Biochemistry detection micro-fluidic chip is multifunction system chip, often be referred to as chip lab (Lab-on-a-chip), this chip is formed in integrated for the basic operation units such as the sample preparation involved by biochemistry detection, quantitative sample injection, liquid mixing, biochemical reaction, separation detection or baseset on the chip of several square centimeters, is a kind of technology platform of the various functions replacing conventional chemical or biology laboratory.The essential characteristic of micro-fluidic chip and sharpest edges are by integrated to various monotechnics flexible combination, scale on the small platform that entirety is controlled.Reagent is pre-packaged is the household function that micro-fluidic chip is applied at portable analysis detection field.Current, in existing micro-fluidic chip system, the pre-packaged and long-term preservation method of reagent is often left in the basket.Before microfluidic system operation, the process of liquid needs artificial sample introduction consuming time or the large and immovable sampling device of volume more.Except reagent sample introduction, reliable reagent pre-packaged unlatching mechanism is also very important.Current, how the unlatching of pre-packaged reagent is opened by micro-valve and is realized, and this can not meet the requirement of actual conditions to chip stability and vibration resistance.
Utility model content
The purpose of this utility model is to provide the pre-packaged micro-fluidic chip of a kind of reagent and using method thereof, and it in micro-fluidic chip, decreases operator's load procedure by pre-packaged for reaction reagent.
In order to solve the problems of the technologies described above, the utility model provides the pre-packaged micro-fluidic chip of a kind of reagent, the pre-packaged micro-fluidic chip of described reagent adopts multilayer to arrange, and comprises from top to bottom: reagent reserve liquid layer, intermediate connecting layer, microchannel layers, hybrid reaction layer.
Further, described reagent reserve liquid layer distributes some liquid storage tanks, and described intermediate connecting layer is provided with some through holes, and described microchannel layers is provided with some microchannels, is provided with reaction tank in described hybrid reaction layer; Described each liquid storage tank is communicated with reaction tank by respective through hole and microchannel respectively successively.
Further, the porch of described through hole or microchannel is sealed by paraffin, and is inlaid with some heater strips in intermediate connecting layer, and each heater strip is set around sealing place of corresponding paraffin respectively, to be suitable for melting paraffin after electrified regulation; And being also provided with a tracheae in described reaction tank, described tracheae is positioned at the side wall upper part of reaction tank; When reagent reacting, by air in described tracheae abstraction reaction pond, make to form negative pressure in reaction tank, by this negative pressure, the reagent in reagent reserve liquid layer is flowed in reaction tank.
Further, the pre-packaged micro-fluidic chip of described reagent also comprises: lay respectively at the diaphragm seal on the lateral surface of reagent reserve liquid layer and hybrid reaction layer; And described reagent reserve liquid layer, intermediate connecting layer, microchannel layers, hybrid reaction layer are all adopted and are consisted of film.
Another aspect, the utility model additionally provides the using method of the pre-packaged micro-fluidic chip of a kind of reagent, comprises the steps:
Step S1, to the heating of reagent pre-packaged micro-fluidic chip, to make reagent reserve liquid layer in the pre-packaged micro-fluidic chip of reagent and the conducting of hybrid reaction layer;
Step S2, extrudes the upper surface of the pre-packaged micro-fluidic chip of reagent, makes the reagent in reagent reserve liquid layer flow in the reaction tank in hybrid reaction layer; And/or by air in a tracheae abstraction reaction pond, to make to form negative pressure in reaction tank, by this negative pressure, the reagent in reagent reserve liquid layer is flowed in reaction tank.
Further, the pre-packaged micro-fluidic chip of described reagent adopts multilayer to arrange, and is reagent reserve liquid layer, intermediate connecting layer, microchannel layers, hybrid reaction layer from top to bottom, and each layer is all adopted and consisted of film;
Described reagent reserve liquid layer distributes some liquid storage tanks, and described intermediate connecting layer is provided with some through holes, and described microchannel layers is provided with some microchannels, is provided with reaction tank in described hybrid reaction layer; Described each liquid storage tank is communicated with reaction tank by respective through hole and microchannel respectively successively;
The porch of described through hole or microchannel is sealed by paraffin, and is inlaid with some heater strips in intermediate connecting layer, and each heater strip is set around sealing place of corresponding paraffin respectively;
To the pre-packaged micro-fluidic chip heating of reagent in described step S1, to make reagent reserve liquid layer and the conducting of hybrid reaction layer; That is, by each heater strip electrified regulation respectively, to melt paraffin, each liquid storage tank is communicated with respectively with reaction tank.
In order to realize supporting the use of with reagent pre-packaged micro-fluidic chip, the utility model additionally provides the experiment instrument of the pre-packaged micro-fluidic chip of a kind of reagent.
Described experiment instrument comprises: the pre-packaged micro-fluidic chip operating platform of the reagent for the pre-packaged micro-fluidic chip of fixating reagent, for the supply module of the pre-packaged micro-fluidic chip heating of reagent, and above described reagent pre-packaged micro-fluidic chip operating platform, be also provided with the pressurizing unit being suitable for extruding the pre-packaged micro-fluidic chip upper surface of reagent; Described supply module, pressurizing unit control by processor module, with after the pre-packaged micro-fluidic chip of reagent is heated to uniform temperature, control the upper surface of the pre-packaged micro-fluidic chip of pressurizing unit extruding reagent.
Further, the pre-packaged micro-fluidic chip of described reagent adopts multilayer to arrange, and comprises from top to bottom: reagent reserve liquid layer, intermediate connecting layer, microchannel layers, hybrid reaction layer, and each layer is all adopted and consisted of film; Described reagent reserve liquid layer distributes some liquid storage tanks, and each liquid storage tank is communicated with the reaction tank in hybrid reaction layer respectively by the respective microchannels in the respective through hole of intermediate connecting layer and microchannel layers; Also be provided with a tracheae in described reaction tank, described tracheae is positioned at the side wall upper part of reaction tank; The porch of described through hole or microchannel is sealed by paraffin, and is inlaid with heater strip in intermediate connecting layer, and each heater strip is set around sealing place of corresponding paraffin respectively; The multi-channel output of described supply module is connected with the energization input of each heater strip respectively, and this supply module controls multiple-channel output by processor module; Described experiment instrument also comprises: the air pump controlled by described processor module, and described air pump is suitable for by the air in tracheae abstraction reaction pond, makes to form negative pressure in reaction tank, by this negative pressure, the reagent in reagent reserve liquid layer is flowed in reaction tank.
Another aspect, the utility model additionally provides a kind of method of work of experiment instrument of the described pre-packaged micro-fluidic chip of reagent.
The method of work of described experiment instrument comprises the steps:
Step S1, controls each heater strip by processor module and heats at the same time or separately, to make each liquid storage tank difference or the conducting of simultaneous reactions pond;
Step S2, described processor module controls the upper surface of the pre-packaged micro-fluidic chip of pressurizing unit extruding reagent, clamp-ons in reaction tank respectively or simultaneously to make each liquid storage tank by medicament; And/or by air in a tracheae abstraction reaction pond, to make to form negative pressure in reaction tank, by this negative pressure, the reagent in reagent reserve liquid layer is flowed in reaction tank.
The beneficial effects of the utility model are, (1) in micro-fluidic chip, decreases operator's load procedure by pre-packaged for reaction reagent; (2) micro-fluidic chip of the pre-packaged reagent that responds can realize reagent robotization and moves in the reaction tank of hybrid reaction layer in experiment instrument; (3) the pre-packaged micro-fluidic chip of reagent can adopt the form of multilayer film to realize, thus breaks away from the past based on the processing technology of bulk material (having certain thickness), can realize low cost, quick large batch of production.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the utility model is further illustrated.
Fig. 1 shows the structural representation of the pre-packaged micro-fluidic chip of reagent of the present utility model;
Fig. 2 shows the structural representation of intermediate connecting layer of the present utility model;
Fig. 3 shows the structural representation of the experiment instrument of the pre-packaged micro-fluidic chip of reagent of the present utility model;
Fig. 4 shows the control block diagram of the experiment instrument of the pre-packaged micro-fluidic chip of reagent of the present utility model.
In figure: reagent reserve liquid layer 1, intermediate connecting layer 2, microchannel layers 3, hybrid reaction layer 4, paraffin 5, heater strip 6, power supply interface 7, diaphragm seal 8, liquid storage tank 101, microchannel 301, reaction tank 401, tracheae 402, the pre-packaged micro-fluidic chip of reagent 10, the pre-packaged micro-fluidic chip operating platform 11 of reagent, pressurizing unit 12, crushing block 121, supply module 122, air pump 123.
Embodiment
By reference to the accompanying drawings the utility model is described in further detail now.These accompanying drawings are the schematic diagram of simplification, only basic structure of the present utility model are described in a schematic way, and therefore it only shows the formation relevant with the utility model.
Embodiment 1
As shown in Figure 1, the pre-packaged micro-fluidic chip of a kind of reagent of the present utility model, the pre-packaged micro-fluidic chip of described reagent adopts multilayer to arrange, and comprises from top to bottom: reagent reserve liquid layer 1, intermediate connecting layer 2, microchannel layers 3, hybrid reaction layer 4.
The utility model in micro-fluidic chip, thus makes kit integrated concentration in the past on a slice chip by pre-packaged for reaction reagent, decreases load procedure.
Described reagent reserve liquid layer 1 distributes some liquid storage tanks 101, and each liquid storage tank 101 is communicated with the reaction tank 401 in hybrid reaction layer 4 respectively respectively by the respective microchannels 301 in the respective through hole of intermediate connecting layer 2 and microchannel layers.
The porch of described through hole or microchannel seals (using paraffin as valve by paraffin 5, it is made to melt by heating, through hole or microchannel conducting), and in intermediate connecting layer 2, be inlaid with some heater strips 6, and each heater strip 6 is set around sealing place of corresponding paraffin 5 respectively, to be suitable for melting paraffin 5 after electrified regulation.As depicted in figs. 1 and 2, Fig. 1 and Fig. 2 is sealed into example with through hole by paraffin 5.The mode that the porch of microchannel is sealed by paraffin 5 and the present embodiment similar, those skilled in the art can directly draw by being sealed into example with through hole by paraffin 5 technical scheme that the porch of microchannel is sealed by paraffin 5.
Further, be also provided with a tracheae 402 in described reaction tank 401, described tracheae is positioned at the top of reaction tank 401 sidewall; When reagent reacting, by air in described tracheae 402 abstraction reaction pond 401, make to form negative pressure in reaction tank 401, by this negative pressure, the reagent in reagent reserve liquid layer is flowed in reaction tank 401.
The exit of described tracheae 402 is provided with sealing film (not shown in FIG.), and sealing film can be torn in use, seals at ordinary times, prevents reaction tank 401 contaminated.
The power supply interface 7 of the energization input formation of described heater strip is positioned at the side of the pre-packaged micro-fluidic chip 10 of agent, and this power supply interface 7 connects power supply, makes heater strip heating power, to melt paraffin, makes through hole or microchannel 301 conducting.
The pre-packaged micro-fluidic chip of described reagent also comprises: lay respectively at the diaphragm seal 8 on the lateral surface of reagent reserve liquid layer and hybrid reaction layer.Wherein, described diaphragm seal 8 adopts the high air tight property composite membrane of PP/EVOH/PP, significantly reduces the volatilizing loss of reagent within the shelf-life.
Described reagent reserve liquid layer 1, intermediate connecting layer 2, microchannel layers 3, hybrid reaction layer 4 are all adopted and are consisted of film, thus break away from the past based on the processing technology of bulk material (having certain thickness), can realize low cost, quick large batch of production.
Embodiment 2
On embodiment 1 basis, the utility model additionally provides the using method of the pre-packaged micro-fluidic chip of a kind of reagent, comprises the steps:
Step S1, heats the pre-packaged micro-fluidic chip 10 of reagent, to make reagent reserve liquid layer in the pre-packaged micro-fluidic chip of reagent 1 and hybrid reaction layer 4 conducting; And step S2, the upper surface of the pre-packaged micro-fluidic chip 10 of reagent is extruded, makes the reagent in reagent reserve liquid layer 1 flow in the reaction tank 401 in hybrid reaction layer 4; And/or by air in a tracheae 402 abstraction reaction pond 401, to make to form negative pressure in reaction tank, by this negative pressure, the reagent in reagent reserve liquid layer is flowed in reaction tank.
Concrete, the pre-packaged micro-fluidic chip of described reagent adopts multilayer to arrange, and is reagent reserve liquid layer 1, intermediate connecting layer 2, microchannel layers 3, hybrid reaction layer 4 from top to bottom, and each layer is all adopted and consisted of film; Described reagent reserve liquid layer distributes some liquid storage tanks 1, and each liquid storage tank 1 is communicated with the reaction tank 401 in hybrid reaction layer 4 respectively respectively by the respective microchannels 301 in the respective through hole of intermediate connecting layer 2 and microchannel layers; The porch of described through hole or microchannel is sealed by paraffin 5, and is inlaid with some heater strips 6 in intermediate connecting layer 2, and each heater strip 6 is set around sealing place of corresponding paraffin 5 respectively.
To the pre-packaged micro-fluidic chip heating of reagent in described step S1, to make reagent reserve liquid layer 1 and hybrid reaction layer 2 conducting; That is, by each heater strip 6 electrified regulation respectively, to melt paraffin 5, each liquid storage tank 101 is communicated with respectively with reaction tank 401.
And the power-up sequence of each heater strip 6 can be set, to adjust reagent release sequence in liquid storage tank 101, meet some particular experiment needs.
And instantaneously big current is accessed to heater strip 6, make its instantaneous reach paraffin melting temperature after, stop heating.By setting electric current, experimentally obtain paraffin melting current value.
Or by temperature sensor, the miniature probe of temperature sensor is stretched near each valve, to detect heating-up temperature.
Reagent is insoluble to, so it is contaminated to avoid reagent after paraffin melting.
After paraffin melting, to form through hole below the inwall that can hang over the porch of through hole or microchannel, reagent is flowed out smoothly.
Embodiment 3
As shown in Figure 3 and Figure 4, on the basis of embodiment 1 and embodiment 2, the utility model additionally provides the experiment instrument of the pre-packaged micro-fluidic chip of a kind of reagent, comprise: the pre-packaged micro-fluidic chip operating platform 11 of the reagent for the pre-packaged micro-fluidic chip of fixating reagent 10, for the supply module 122 of the pre-packaged micro-fluidic chip heating of reagent, and above described reagent pre-packaged micro-fluidic chip operating platform 11, be also provided with the pressurizing unit 12 being suitable for extruding the pre-packaged micro-fluidic chip upper surface of reagent; Described supply module 122, pressurizing unit 12 control by processor module, with after the pre-packaged micro-fluidic chip of reagent is heated to uniform temperature, control the upper surface of the pre-packaged micro-fluidic chip of pressurizing unit extruding reagent.
Concrete, described pressurizing unit 12 comprises: some crushing blocks 121, each crushing block aims at each liquid storage tank 101 respectively, described pressurizing unit 12 is driven by main screw body and moves up and down, to extrude each liquid storage tank 101, described processor module controls the upper and lower motion of screw mandrel drive crushing block by controlling screw mandrel drive motor.
Preferably, independent telescope device is also respectively equipped with in described each crushing block 121, and each independent telescope device adopts miniature screw mandrel, and regulate corresponding crushing block 121 to stretch respectively by each miniature screw mandrel, can be squeezed to meet the part liquid storage tank 101 that in each liquid storage tank 101, needs participate in testing, enter reaction tank 401.
Concrete, crushing block 121 adopts hollow structure, and feed screw nut installs therein, described feed screw nut coordinates with miniature screw mandrel and forms independent screw body, each miniature screw mandrel rotates respectively by respective drive driven by motor, to control corresponding crushing block 121 independent telescope, and the head of described crushing block 121 can also adopt rubber structure, makes pressure more even.By the crushing block 121 of this scheme, can realize extruding respectively each liquid storage tank 101, and realize each reagent according to the interpolation of different orders, meet special occasions biological reagent reaction needed.
The pre-packaged micro-fluidic chip of described reagent adopts multilayer to arrange, and comprises from top to bottom: reagent reserve liquid layer 1, intermediate connecting layer 2, microchannel layers 3, hybrid reaction layer 4, and each layer is all adopted and consisted of film; Described reagent reserve liquid layer distributes some liquid storage tanks 101, and each liquid storage tank 101 is communicated with the reaction tank 401 in hybrid reaction layer 4 respectively by the respective microchannels 301 in the respective through hole of intermediate connecting layer 2 and microchannel layers; , be also provided with a tracheae 402 in described reaction tank 401, described tracheae is positioned at the top of reaction tank 401 sidewall; The porch of described through hole or microchannel 301 is sealed by paraffin 5, and is inlaid with heater strip 6 in intermediate connecting layer 2, and each heater strip 6 is set around sealing place of corresponding paraffin 5 respectively; The multi-channel output of described supply module 122 is connected with the energization input of each heater strip respectively, and this supply module 122 controls multiple-channel output by processor module.The multi-channel output of described supply module 122 can insert the power supply interface 7 of the energization input formation of each heater strip.
Concrete, on each outlet line of the multi-channel output of described supply module 122 respectively in be provided with respective switch pipe, and each switching tube is controlled (concrete respectively by processor module, the control end base stage of each switching tube is connected with the multi-channel output of processor module respectively), which can set paraffin as required by processor module to need to melt, and then reagent in each liquid storage tank 101 can be regulated to flow into the order in reaction tank 401, meet multiple test or experiment needs; And because described reagent reserve liquid layer 1, intermediate connecting layer 2, microchannel layers 3, hybrid reaction layer 4 are all adopted and consisted of film, therefore, each layer all has certain elasticity, so without the need to worrying that microchannel is when non-conducting, liquid storage tank 101 can be extruded and burst.Once paraffin melting, microchannel conducting, then by the slight extruding of crushing block, then can enter corresponding liquid storage tank 101 in reaction tank 401.
Described experiment instrument also comprises: the air pump 123 controlled by described processor module, and described air pump 123 is suitable for by the air in tracheae 402 abstraction reaction pond, makes to form negative pressure in reaction tank 401, by this negative pressure, the reagent in reagent reserve liquid layer is flowed in reaction tank.
Embodiment 4
On embodiment 3 basis, the utility model additionally provides a kind of method of work of experiment instrument of the described pre-packaged micro-fluidic chip of reagent.
The method of work of described experiment instrument comprises the steps:
Step S1, controls each heater strip 5 by processor module and heats at the same time or separately, to make each liquid storage tank 101 difference or simultaneous reactions pond 401 conducting;
Step S2, described processor module controls the upper surface of the pre-packaged micro-fluidic chip 10 of pressurizing unit extruding reagent, clamp-ons in reaction tank 401 respectively or simultaneously by medicament to make each liquid storage tank 101; And/or by air in a tracheae 402 abstraction reaction pond 401, to make to form negative pressure in reaction tank, by this negative pressure, the reagent in reagent reserve liquid layer is flowed in reaction tank.
In the present embodiment, the pre-packaged micro-fluidic chip of reagent can see embodiment 1 and embodiment 2 associated description.
Concrete, described processor module can also be connected with touch-screen or display module, key-press module, to input command adapted thereto.
With above-mentioned according to desirable embodiment of the present utility model for enlightenment, by above-mentioned description, relevant staff in the scope not departing from this utility model technological thought, can carry out various change and amendment completely.The technical scope of this utility model is not limited to the content on instructions, must determine its technical scope according to right.
Claims (6)
1. the pre-packaged micro-fluidic chip of reagent, is characterized in that, the pre-packaged micro-fluidic chip of described reagent comprises from top to bottom: reagent reserve liquid layer, intermediate connecting layer, microchannel layers, hybrid reaction layer.
2. the pre-packaged micro-fluidic chip of reagent as claimed in claim 1, it is characterized in that, described reagent reserve liquid layer distributes some liquid storage tanks, and described intermediate connecting layer is provided with some through holes, described microchannel layers is provided with some microchannels, is provided with reaction tank in described hybrid reaction layer; Described each liquid storage tank is communicated with reaction tank by respective through hole and microchannel respectively successively.
3. the pre-packaged micro-fluidic chip of reagent as claimed in claim 2, it is characterized in that, the porch of described through hole or microchannel is sealed by paraffin, and in intermediate connecting layer, be inlaid with some heater strips, and each heater strip is set around sealing place of corresponding paraffin respectively, to be suitable for melting paraffin after electrified regulation; And
Also be provided with a tracheae in described reaction tank, described tracheae is positioned at the side wall upper part of reaction tank;
When reagent reacting, by air in described tracheae abstraction reaction pond, make to form negative pressure in reaction tank, by this negative pressure, the reagent in reagent reserve liquid layer is flowed in reaction tank.
4. the pre-packaged micro-fluidic chip of reagent as claimed in claim 3, it is characterized in that, this chip also comprises: lay respectively at the diaphragm seal on the lateral surface of reagent reserve liquid layer and hybrid reaction layer; And
Described reagent reserve liquid layer, intermediate connecting layer, microchannel layers, hybrid reaction layer are all adopted and are consisted of film.
5. an experiment instrument for the pre-packaged micro-fluidic chip of reagent, is characterized in that, comprising:
The pre-packaged micro-fluidic chip operating platform of reagent for the pre-packaged micro-fluidic chip of fixating reagent, for the supply module of the pre-packaged micro-fluidic chip heating of reagent, and above described reagent pre-packaged micro-fluidic chip operating platform, be also provided with the pressurizing unit being suitable for extruding the pre-packaged micro-fluidic chip upper surface of reagent;
Described supply module, pressurizing unit control by processor module, with after the pre-packaged micro-fluidic chip of reagent is heated to uniform temperature, control the upper surface of the pre-packaged micro-fluidic chip of pressurizing unit extruding reagent;
The pre-packaged micro-fluidic chip of described reagent adopts multilayer to arrange, and comprises from top to bottom: reagent reserve liquid layer, intermediate connecting layer, microchannel layers, hybrid reaction layer, and each layer is all adopted and consisted of film.
6. experiment instrument according to claim 5, it is characterized in that, described reagent reserve liquid layer distributes some liquid storage tanks, and each liquid storage tank is communicated with the reaction tank in hybrid reaction layer respectively by the respective microchannels in the respective through hole of intermediate connecting layer and microchannel layers, also be provided with a tracheae in described reaction tank, described tracheae is positioned at the side wall upper part of reaction tank;
The porch of described through hole or microchannel is sealed by paraffin, and is inlaid with heater strip in intermediate connecting layer, and each heater strip is set around sealing place of corresponding paraffin respectively;
The multi-channel output of described supply module is connected with the energization input of each heater strip respectively, and this supply module controls multiple-channel output by processor module;
Described experiment instrument also comprises: the air pump controlled by described processor module, and described air pump is suitable for by the air in tracheae abstraction reaction pond, makes to form negative pressure in reaction tank, by this negative pressure, the reagent in reagent reserve liquid layer is flowed in reaction tank.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520781171.2U CN205015354U (en) | 2015-10-10 | 2015-10-10 | Reagent encapsulates micro -fluidic chip in advance and experiment appearance thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520781171.2U CN205015354U (en) | 2015-10-10 | 2015-10-10 | Reagent encapsulates micro -fluidic chip in advance and experiment appearance thereof |
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| CN205015354U true CN205015354U (en) | 2016-02-03 |
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| CN201520781171.2U Expired - Fee Related CN205015354U (en) | 2015-10-10 | 2015-10-10 | Reagent encapsulates micro -fluidic chip in advance and experiment appearance thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106568980A (en) * | 2015-10-10 | 2017-04-19 | 上海旭瀚科技有限公司 | Reagent pre-packaged micro-fluidic chip, application method, experimental instrument and operating method |
| CN107308997A (en) * | 2017-06-22 | 2017-11-03 | 浙江诺迦生物科技有限公司 | A kind of micro-fluidic chip convenient type Ngatively pressurized sampling device based on miniature suction ball |
-
2015
- 2015-10-10 CN CN201520781171.2U patent/CN205015354U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106568980A (en) * | 2015-10-10 | 2017-04-19 | 上海旭瀚科技有限公司 | Reagent pre-packaged micro-fluidic chip, application method, experimental instrument and operating method |
| CN106568980B (en) * | 2015-10-10 | 2018-01-26 | 上海旭瀚科技有限公司 | The pre-packaged micro-fluidic chip of reagent, application method and experiment instrument and method of work |
| CN107308997A (en) * | 2017-06-22 | 2017-11-03 | 浙江诺迦生物科技有限公司 | A kind of micro-fluidic chip convenient type Ngatively pressurized sampling device based on miniature suction ball |
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