CN204897932U - Fermentation cylinder that production hyaluronic acid used - Google Patents
Fermentation cylinder that production hyaluronic acid used Download PDFInfo
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- CN204897932U CN204897932U CN201520644526.3U CN201520644526U CN204897932U CN 204897932 U CN204897932 U CN 204897932U CN 201520644526 U CN201520644526 U CN 201520644526U CN 204897932 U CN204897932 U CN 204897932U
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- agitator
- hyaluronic acid
- fermentor tank
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Abstract
The utility model discloses a fermentation cylinder that production hyaluronic acid used, including jar body and a motor, the internal (mixing) shaft that is equipped with of jar, the upper end of (mixing) shaft is located to the motor, install defoaming device and multilayer agitator on the (mixing) shaft from top to bottom in proper order, jar internal be equipped with two pH electrodes, the pH electrode is connected with controlling means through the wire, and a jar internal bottom is equipped with the air sparger, the air sparger is connected with the intake pipe, jar body bottom is equipped with blowing pipe and steam pipe. The utility model discloses normal range that can the automatic control pH value guarantees the normal clear of thallus fermentation, the emergence of jar phenomenon of avoiding boiling to enable the abundant mixture of material, accelerate fermentation process.
Description
Technical field
The utility model relates to fermentation equipment used in a kind of microbial fermentation engineering, especially a kind of fermentor tank producing hyaluronic acid.
Background technology
At present, hyaluronic production method mainly contains two kinds: one extracts from animal tissues's (as rooster comb), and another kind is that microbe fermentation method is produced.Owing to extracting the needs that can not meet a large amount of process for processing from animal tissues, adopt microbe fermentation method now more.
Fermentor tank is the outside atmosphere device that microorganism grows, breeds and formed product during the fermentation.In hyaluronic fermentation production process, along with the growth of time, in fermentor tank, the acidity of liquid is more and more stronger, if adjust the pH value of fermentation pot liquid not in time, causes pH value too low, will have a strong impact on the normal fermentation of microorganism.In fermenting process, in order to adjust the pH value of feed liquid, need to add alkali lye in tank, alkali lye generally adds from tank body top, so just easily causes the pH value of tank body top feed liquid higher, particularly fermentation middle and later periods viscosity along with the time increasing, feed liquid is inadequate because stirring dynamics, and the alkali lye added from top falls apart not open, and causes local ph too high, kill part microorganism, fermenting process is affected.
Utility model content
For the deficiencies in the prior art, the purpose of this utility model is to provide a kind of fermentor tank producing hyaluronic acid, rationally, effectively can control the scope of the pH value needed for fermentable, ensures normally carrying out of fermentation.
For achieving the above object, the technical solution adopted in the utility model is: a kind of fermentor tank producing hyaluronic acid, comprise tank body and motor, it is characterized in that: in described tank body, be provided with stir shaft, the upper end of stir shaft is located at by described motor, described stir shaft is provided with defoaming device and multilayer agitator from top to bottom successively, two pH electrode are provided with in described tank body, described pH electrode is connected with control device by wire, tank body inner bottom part is provided with air-distributor, described air-distributor is connected with inlet pipe, described tank base is provided with vomit pipe and vapour pipe.
Described multilayer agitator is four layers, described agitator is followed successively by the first agitator, the second agitator, the 3rd agitator and the 4th agitator from top to bottom, described first agitator is the straight paddle stirrer of two oblique leaves, described second agitator is six curved leaf disc turbine type agitators, described 3rd agitator is three leaf propeller agitators, and described 4th agitator is six arc leaf disc turbine type agitators.
Described control device is PLC, can the upper and lower limit of control ph automatically, ensures the home needed for thalline fermentation.
Described air-distributor is connected with inlet pipe by an air filter, and the air entered in tank body first passes through and filters, and ensure cleaning in tank body, avoiding miscellaneous bacteria to enter in tank body affects ferment effect.
Described air-distributor is ring pipe, is convenient to air and fully mixes with feed liquid.
Described vomit pipe is connected by T-valve with vapour pipe, is jointly connected to tank base, decreases the setting of tank body upper shed.
The beneficial effects of the utility model are: in fermentor tank tank body, upper and lower parts are provided with two pH electrode, pH electrode above controls the upper limit of fermented liquid pH value, pH electrode below controls the lower limit of fermented liquid pH value, the normal range of control ph well, ensure normally carrying out of thalline fermentation, not easily cause the problems such as dead bacterium.In fermenting process, along with the rotation of stir shaft, agitator constantly stirs fermented liquid, easily cause liquid to produce foam, foam too much just produces tank phenomenon of boiling, and stir shaft top is provided with defoaming device, the foam produced in fermenting process can be eliminated in time, the generation of tank phenomenon of avoiding boiling.
Multilayer agitator is followed successively by the straight paddle stirrer of two oblique leaves, six curved leaf disc turbine type agitators, three leaf propeller agitators, six arc leaf disc turbine type agitators from top to bottom, the superiors adopt axialmode agitator, feed liquid can be broken up, feed liquid is fully mixed, its excess-three layer adopts radial mode turbine agitator, the viscosity of fermentation later stage material increases gradually, adopt multilayer turbine agitator, the stirring to material can be realized well, and the bubble produced in crushing, stirring process.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model.
In figure: 1-control device, 2-pH electrode, 3-tank body, 4-motor, 5-stir shaft, 6-defoaming device, 7.1-first agitator, 7.2-second agitator, 7.3-the 3rd agitator, 7.4-the 4th agitator, 8-air-distributor, 9-air filter, 10-vomit pipe, 11-vapour pipe.
Embodiment
Below in conjunction with the drawings and the specific embodiments, the utility model is further described.
As shown in the figure: a kind of fermentor tank producing hyaluronic acid, comprise tank body 3 and motor 4, it is characterized in that: in described tank body 3, be provided with stir shaft 5, the upper end of stir shaft 5 is located at by described motor 4, described stir shaft 5 is provided with successively defoaming device 6 and four layers of agitator from top to bottom, described agitator is followed successively by the first agitator 7.1 from top to bottom, second agitator 7.2, 3rd agitator 7.3 and the 4th agitator 7.4, described first agitator 7.1 is the straight paddle stirrer of two oblique leaves, described second agitator 7.2 is six curved leaf disc turbine type agitators, described 3rd agitator 7.3 is three leaf propeller agitators, described 4th agitator 7.4 is six arc leaf disc turbine type agitators, two pH electrode are provided with in described tank body 3, described pH electrode 2 is connected with PLC 1 by wire, tank body 3 inner bottom part is provided with ring pipe air-distributor 8, described air-distributor 8 is connected with inlet pipe by an air filter 9, vomit pipe 10 and vapour pipe 11 is provided with bottom described tank body 3, vomit pipe 10 and vapour pipe 11 are connected to the bottom of tank body 3 jointly by T-valve.
The foregoing is only preferred embodiment of the present utility model, is not to restriction of the present utility model.The change that those of ordinary skill in the art makes in essential scope of the present utility model, remodeling, interpolation or replacement, also should belong to protection domain of the present utility model.
Claims (8)
1. produce the fermentor tank of hyaluronic acid for one kind, comprise tank body and motor, it is characterized in that: in described tank body, be provided with stir shaft, the upper end of stir shaft is located at by described motor, and described stir shaft is provided with defoaming device and multilayer agitator from top to bottom successively, is provided with two pH electrode in described tank body, described pH electrode is connected with control device by wire, tank body inner bottom part is provided with air-distributor, and described air-distributor is connected with inlet pipe, and described tank base is provided with vomit pipe and vapour pipe.
2. the fermentor tank of production hyaluronic acid according to claim 1, is characterized in that: described multilayer agitator is four layers.
3. the fermentor tank of production hyaluronic acid according to claim 2, it is characterized in that: described agitator is followed successively by the first agitator, the second agitator, the 3rd agitator and the 4th agitator from top to bottom, described first agitator is the straight paddle stirrer of two oblique leaves, described second agitator is six curved leaf disc turbine type agitators, described 3rd agitator is three leaf propeller agitators, and described 4th agitator is six arc leaf disc turbine type agitators.
4. the fermentor tank of the production hyaluronic acid according to claim 1 or 2 or 3, is characterized in that: described control device is PLC.
5. the fermentor tank of the production hyaluronic acid according to claim 1 or 2 or 3, is characterized in that: described two pH electrode lay respectively at the upper and lower of fermentor tank tank body.
6. the fermentor tank of production hyaluronic acid according to claim 4, is characterized in that: described air-distributor is connected with inlet pipe by an air filter.
7. the fermentor tank of the production hyaluronic acid according to claim 1 or 2 or 3, is characterized in that: described air-distributor is ring pipe.
8. the fermentor tank of the production hyaluronic acid according to claim 1 or 2 or 3, is characterized in that: described vomit pipe is connected by T-valve with vapour pipe.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520644526.3U CN204897932U (en) | 2015-08-25 | 2015-08-25 | Fermentation cylinder that production hyaluronic acid used |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520644526.3U CN204897932U (en) | 2015-08-25 | 2015-08-25 | Fermentation cylinder that production hyaluronic acid used |
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| Publication Number | Publication Date |
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| CN204897932U true CN204897932U (en) | 2015-12-23 |
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| CN201520644526.3U Active CN204897932U (en) | 2015-08-25 | 2015-08-25 | Fermentation cylinder that production hyaluronic acid used |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106222071A (en) * | 2016-07-25 | 2016-12-14 | 柳州合科技有限公司 | A kind of organic matter fermentation agitating device being easy to clean |
| CN106222070A (en) * | 2016-07-25 | 2016-12-14 | 柳州合科技有限公司 | A kind of organic matter fermentation agitating device |
-
2015
- 2015-08-25 CN CN201520644526.3U patent/CN204897932U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106222071A (en) * | 2016-07-25 | 2016-12-14 | 柳州合科技有限公司 | A kind of organic matter fermentation agitating device being easy to clean |
| CN106222070A (en) * | 2016-07-25 | 2016-12-14 | 柳州合科技有限公司 | A kind of organic matter fermentation agitating device |
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| GR01 | Patent grant |