CN204839829U - Shower nozzle device and parcel system with automatically, wrap up function - Google Patents

Shower nozzle device and parcel system with automatically, wrap up function Download PDF

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Publication number
CN204839829U
CN204839829U CN201520289726.1U CN201520289726U CN204839829U CN 204839829 U CN204839829 U CN 204839829U CN 201520289726 U CN201520289726 U CN 201520289726U CN 204839829 U CN204839829 U CN 204839829U
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China
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urceolus
parcel
inner core
ejecting device
valve
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CN201520289726.1U
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Chinese (zh)
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周惠兴
凌刚
刘焕宝
刘颖
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Sichuan Revotek Co ltd
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Individual
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Abstract

The utility model discloses a have automatic shower nozzle device, parcel system and parcel method of wrapping up the function, including automatic parcel systems such as shower nozzle device such as inner tube, urceolus, fixed plate, sealing washer and air supply, relief pressure valve, servovalve, pressure sensor, ooff valve, controller, ink horn, shower nozzle devices. There are central inner chamber, central spout, annular channel, parcel chamber, active biomaterial entry and wrapper entry in the shower nozzle device. In automatic parcel system, adjust and control parcel pressure by the controller, realization wrapper is to active biomaterial's automatic parcel, the parcel granule area that obtains continuous parcel strip and press certain distance distribution. The utility model discloses can effectively protect biomaterial's biological activity, the pair cell damage is little, improves the spatial structure intensity of printing the organ that the in -process is printed.

Description

A kind of ejecting device and baggage systems with automatic parcel function
Technical field
The present invention relates to the shower nozzle manufacturing technology in field of tissue engineering technology, relate to a kind of ejecting device that can realize active biomaterial parcel.
Background technology
In 20th century, the organ disease patient in the whole world nearly 1,000,000 obtains new life by organ transplantation, but the acquisition of organ is premised on the losing of organ.According to statistics, the patient that annual trouble uremia of China carries out dialysis treatment has 1,200,000 people, have a liver complaint and need the patient of liver transplantation to have 1,000,000 people, but the patient that can have an opportunity to accept kidney and liver transplantation is very few.Supply due to organ is far smaller than the demand of organ, and the greatest problem that organ transplantation faces how to obtain the transplantable organ of sufficient amount.Building human organ by 3D biometric print, is a kind of new technological approaches solving organ supply in filed of organ transplantation.
It is utilize 3D biometric print machine to be printed on biological support or platform according to certain rules by active biomaterial (set of such as cell and cell) that 3D living body biological prints, and forms the stereoeffect of organ; Then, by biological culturing method, the active biomaterial of printing shaping is trained specific organ.How to make active biomaterial be protected in print procedure and keep biological activity, and form ad hoc structure organ shape, printing head is one of key device.
Summary of the invention
The present invention discloses a kind of ejecting device, baggage systems and the packaging method that can realize active biomaterial and automatically wrap up.Utilize the present invention in the print procedure of organ, other biology or biocompatible material can be used automatically to wrap up active biomaterial, keep the biological activity of biomaterial and the stability of organ structure.
Realizing the object of the invention technical scheme is: the ejecting device that a kind of active biomaterial wraps up automatically, and the automatic baggage systems utilizing this ejecting device to wrap up active biomaterial and automatic packaging method.
The ejecting device that active biomaterial wraps up automatically, comprises inner core, urceolus, fixing head, sealing ring, it is characterized in that: there is a stepped inner chamber body on urceolus top, and bottom has one to wrap up chamber, and lateral surface has a urceolus through hole through with inner chamber body; A step is arranged at inner core top, a central lumen, and a center of orifices is arranged at bottom; After installing, inner core and urceolus top are in one plane; Fixing head has through hole, screw hole A (5) and screw hole B (6) in a thickness direction; First in the stepped inner chamber body of urceolus, place sealing ring, then put into inner core, the step on inner core top and the shoulder hole of outer barrel and sealing ring form sealing; Fixing head is buckled in the upper surface of inner core and urceolus, by screw A (5) and screw hole B (6), fixing head, inner core and urceolus is connected as a single entity; The top of inner core central lumen can process female thread to be connected with pipe joint; Be matched in clearance between inner core and urceolus, and between inner core and urceolus, form certain thickness circular passage, and be communicated with the urceolus through hole of urceolus side; It is parcel chamber in the bottom of ejecting device; Be matching relationship between inner core and urceolus, ensure the axiality between center of orifices and parcel chamber, sealing ring prevents the fluid leakage in circular passage.
Be matching relationship between the inner core of ejecting device and urceolus, guarantee that inner core is concentric with urceolus; The circular passage formed between inner core and urceolus can be circle; Can by the fine setting of axial displacement, the thickness of adjustment circular passage.
The profile of ejecting device is one or more combinations of cuboid, cylinder or spheroid; The shape in the inner chamber of ejecting device inner core, circular passage and parcel chamber is cylindrical or taper.
Ejecting device by several independently parts by assembly or one-body molded.
The quantity of the circular passage of ejecting device is one or more; All circular passages are all arranged around center of orifices, and the spacing between circular passage is equal or unequal, and the shape of each circular passage is identical or not identical.
Be one or more with the through hole quantity of circular passage outside urceolus; Through hole is circumferentially symmetric, or asymmetric distribution.
The arbitrary portion of ejecting device or all with metal material, nonmetallic materials, composite one or more manufacture, adopt conventional manufacturing process molding, or adopt 3D to print or powder sintered molding.
A kind of automatic baggage systems using ejecting device, comprise source of the gas, one-level pressure relief valve, filter, second depressurized valve, pressure transducer, three way cock, servo valve A, servo valve B, pressure transducer A, pressure transducer B, print cartridge A, print cartridge B, switch valve A, switch valve B, ejecting device; Source of the gas, one-level pressure relief valve, filter, second depressurized valve and pressure transducer connect successively, are connected respectively by three way cock with servo valve A, servo valve B; Servo valve A is connected with switch valve A, then is connected with the print cartridge A that active biomaterial is housed, and is finally connected with the central lumen on ejecting device; Servo valve B is connected with switch valve B, then is connected with the print cartridge B that lapping is housed, and is finally connected with the urceolus through hole on ejecting device; Respectively regulating and control is carried out to the pressure in print cartridge A, print cartridge B by controller, respectively the open and close of switch valve A, switch valve B are controlled, realize the automatic parcel of lapping to active biomaterial.
The open and close time of pressure in print cartridge and gauge tap valve is regulated by servo valve, automatically wrapping up continuously and interval-automatic parcel of active biomaterial can be realized, enwrapped granule band print platform being formed continuous print parcel band respectively and distributes at a certain distance.
In encapsulation process, active biomaterial is identical with the extrusion pressure of lapping or different, and the two pressure is constant or by function in time.
When the quantity of the circular passage of ejecting device is more than 2 or 2, can realize active biomaterial more than 2 layers or 2 layers parcel automatically; The extrusion pressure of every layer of lapping is identical or different.
Medium in gas return path is nitrogen, argon, water etc., and it and active biomaterial and lapping are without chemical reaction.
In automatic encapsulation process, pulse width modulating technology (PWM) is adopted to control to the opening and closing of controlled valve.
Active biomaterial, not by the impact of other devices, directly completes parcel by ejecting device and extrudes.
Wrapped material is active biomaterial or nonactive biomaterial; Lapping is hydrogel or macromolecular material.
This ejecting device is utilized to the method that active biomaterial carries out automatically parcel to be:
Through hole on ejecting device fixing head is connected with the print cartridge that active biomaterial is housed, and the side through hole on urceolus is connected with the print cartridge that lapping is housed; Two print cartridges are connected with gas return path respectively; Gas return path is made up of source of the gas, one-level pressure relief valve, filter, second depressurized valve, servo valve, switch valve, pressure transducer, controller; Control servo valve by controller and obtain certain steady and continuous pressure, the opening and closing of gauge tap valve, realize the automatic parcel of lapping to active biomaterial.
In the automatic encapsulation process of active biomaterial, there are continuously parcel and interval parcel two kinds of mode of operations.
Under continuous parcel pattern, the step that active biomaterial wraps up automatically is: first, allows controlled valve be in closed condition, cuts off the pressure feed in ejecting device.Second step, opens one-level pressure relief valve and second depressurized valve, makes the gas pressure between second depressurized valve and servo valve reach setting value.3rd step, controls the opening degree of servo valve, regulates the pressure be equipped with in the print cartridge of active biomaterial to setting pressure.4th step, opening switch valve, controls the opening degree of another servo valve, regulates the pressure be equipped with in the print cartridge of lapping to setting pressure.5th step, under pressure, the active biomaterial in print cartridge is advanced the inner core cavity of ejecting device, extrudes from center of orifices, in parcel chamber, be formed centrally continuous print active biomaterial stream; Lapping in print cartridge is extruded from circular passage, forms the continuous print lapping stream of outside ring-type; In the parcel chamber of ejecting device, active biomaterial stream and lapping stream converge, and form certain thickness lapping layer on the surface of active biomaterial, complete the automatic parcel of lapping to active biomaterial.6th step, under the promotion of constant pressure, wrapped active biomaterial stream is discharged continuously from parcel chamber; Closing switch valve wrapping action stops.
Under interval parcel pattern, the step that active biomaterial wraps up automatically is: the first step is identical with continuous parcel pattern to the 5th step.6th step, rapid-closure damper, stops wrapping action; Under capillary effect, lapping material wraps the upper and lower two ends of active biomaterial, forms wrapped active biomaterial microparticle, and discharges from parcel chamber.The opening time of gauge tap valve and closing time interval, obtain a series of wrapped active biomaterial microparticle sequence independent of each other.
Compared with prior art, the invention has the beneficial effects as follows:
1, can realize the automatic parcel of lapping to the single or multiple lift material of active biomaterial, integument thickness is adjustable.
2, under the control of the computer, freely switching between parcel and interval parcel two kinds of mode of operations continuously, active biomaterial parcel can be realized by the requirement of organizational project.The cell particles wrapped can be arranged by the requirement on organ space structure.
3, can the biological activity of available protecting biomaterial, little to cell injury, the organ space structure intensity printed can be controlled.
4, ejecting device structure is simple, draws materials extensively, is easy to manufacture; Encapsulation process controls simple, easily is automated.
Accompanying drawing explanation
Fig. 1 is ejecting device schematic appearance;
The A-A sectional view that Fig. 2 (1) is Fig. 1;
Fig. 2 (2) is the B-B sectional view of Fig. 2 (1);
Fig. 2 (3) is I magnified partial view in Fig. 2 (1).
Fig. 3 global formation two-layer parcel ejecting device structural representation
Fig. 4 is global formation multilamellar parcel ejecting device structural representation;
Fig. 5 is the automatic baggage systems schematic diagram of active biomaterial;
Fig. 6 is active biomaterial encapsulation process schematic diagram under continuous parcel pattern;
Fig. 7 is active biomaterial encapsulation process schematic diagram under interval parcel pattern.
In figure: 1. fixing head; 2. urceolus; 3. inner core; 4. urceolus through hole; 5. screw hole (A); 6. screw hole (B); 7 fixing head through holes; 8. sealing ring; 9. central lumen; 10. center nozzle; 11. circular passages; 12. parcel chambeies; 13. second circular passages; 14. second parcel chambeies; 15. sources of the gas; 16. one-level pressure relief valves; 17 filters; 18. second depressurized valves; 19. pressure transducers; 20. three way cock; 21. servo valves (A); 22. servo valves (B); 23. pressure transducers (A); 24. pressure transducers (B); 25. switch valves (A); 26. switch valves (B); 27. print cartridges (A); 28. print cartridges (B); 29. ejecting devices; 30. active biomaterials; 31. suspensions; 32. lappings; 33. ducts (B); 34. ducts (A).
Detailed description of the invention
Below in conjunction with drawings and Examples, the present invention is further described.
Embodiment one
As shown in Figure 1, Figure 2 shown in (1), Fig. 2 (2) and Fig. 2 (3), this ejecting device is formed by fixing head 1, urceolus 2, inner core 3 and sealing ring 8 assembling parts, wherein: there is a stepped inner chamber body on urceolus 2 top, bottom has one to wrap up chamber 12, and lateral surface has a urceolus through hole 4 through with inner chamber body; A step is arranged at inner core 3 top, a central lumen 9, and bottom has a diameter to be that the center of orifices 10(of 0.15mm is see Fig. 2 (2) and Fig. 2 (3)), inner core 3 is highly less than urceolus 2 height 3mm; Fixing head 1 has through hole 7, screw hole (A) 5 and screw hole (B) 6 in a thickness direction.First in the stepped inner chamber body of urceolus 2, place sealing ring 8, put into inner core 3 again, fixing head 1 is buckled in the upper surface of inner core 3 and urceolus 2, by screw (A) 5 and screw hole (B) 6 screw, fixing head 1, inner core 3 and urceolus 2 is connected as a single entity.At top, central lumen 9 top can produce screw thread and directly be connected with pipe joint; Be matched in clearance between inner core 3 and urceolus 2, and form certain thickness circular passage 11(between inner core 3 and urceolus 2 in bottom see Fig. 2 (2) and Fig. 2 (3)), thickness is 0.1mm, and this circular passage is communicated with urceolus 2 lateral surface through hole 4; In bottom, inner core 3 and urceolus 2 form parcel chamber 12; Be matching relationship between inner core and urceolus, can guarantee to ensure the axiality between center of orifices and parcel chamber; Sealing ring 8 can prevent the fluid leakage in circular passage; The thickness of circular passage 11 regulates pad to finely tune by placing at the step place of inner core 3 and urceolus 2 top.
Fixing head 1, urceolus 2, inner core 3 use has biocompatible materials manufacture, and sealing ring 8 uses the specific rubber manufacture with biocompatibility.
As shown in Figure 5, the system utilizing aforementioned ejecting device to realize active biomaterial automatically to wrap up, comprise source of the gas 15, one-level pressure relief valve 16, filter 17, second depressurized valve 18, pressure transducer 19, three way cock 20, servo valve (A) 21, servo valve (B) 22, pressure transducer (A) 23, pressure transducer (B) 24, print cartridge (A) 27, print cartridge (B) 28, switch valve (A) 25, switch valve (B) 26, aforesaid ejecting device 29.
Be connected with having biocompatible polymer material pipeline between each parts, the order of connection is: source of the gas 15 → one-level pressure relief valve 16 → filter 17 → second depressurized valve 18 → pressure transducer 19; After this gas circuit is divided into two-way by three way cock 20, and wherein a road is: the central lumen 9 on the inner core 3 on three way cock's 20 → servo valve (A) 21 → pressure transducer (A) 23 → switch valve (A) 25 → print cartridge (A) 27 → ejecting device 29; Controller by the control realization of servo valve (A) 21 and switch valve (A) 25 to the control of the pressure P 1 in print cartridge (A) 27.Another road is: the urceolus through hole 4 of three way cock's 20 → servo valve (B) 22 → pressure transducer (B) 24 → switch valve (B) 26 → print cartridge (B) 28 → ejecting device 29 upper side; Controller by the control realization of servo valve (B) 22 and switch valve (B) 26 to the control of the pressure P 2 in print cartridge (B) 28.In print cartridge (A) 27, load active biomaterial and sodium alginate suspension, in print cartridge (B) 28, load hydrogel.
Said system wraps up MODE of operation in continuous parcel pattern or interval respectively, realizes the automatic parcel of hydrogel to active biomaterial and sodium alginate suspension.The former obtains the active biomaterial of outer layer covers hydrogel and the continuous wrap of sodium alginate suspension, and the latter obtains the active biomaterial of outer layer covers hydrogel and the granule of sodium alginate suspension.
As shown in Figure 6, under continuous parcel pattern, the automatic parcel step of hydrogel to active biomaterial and sodium alginate suspension is: first, allows switch valve (A) 25 and switch valve (B) 26 be in closed condition, cuts off the pressure feed in ejecting device 29.Second step, opens one-level pressure relief valve 16 and second depressurized valve 18, makes the gas pressure between second depressurized valve 18 and servo valve (A) 21 and servo valve (B) 22 reach 0.60MPa.3rd step, is controlled the opening degree of servo valve (A) 21, makes by controller. pressure P 1 to the 0.50MPa in pressure transducer (A) 23, and keep stable.4th step, controller controls the opening degree of another servo valve (B) 22, makes. pressure P 2 to the 0.40MPa in pressure transducer (A) 24, and keep stable.5th step, by the synchronous opening switch valve (A) 25 of controller and switch valve (B) 26, under gas pressure effect, active biomaterial in print cartridge (A) 27 and sodium alginate suspension are advanced the inner core cavity 9 of ejecting device 29, extrude from center of orifices 12, in parcel chamber 12, be formed centrally active biomaterial and the sodium alginate suspension stream that diameter is about 0.15mm; Hydrogel in print cartridge (B) 28 is extruded continuously from circular passage 11, the active biomaterial flowed out in inner core cavity 9 and sodium alginate suspension stream are in the centre of the water-setting solation of the ring-type flowed out by circular passage 11, are 0.09 ~ 0.11mm hydrogel layer at the surrounding formation thickness of active biomaterial and sodium alginate suspension stream.6th step, under the promotion of constant pressure, the active biomaterial of outer layer covers hydrogel and sodium alginate suspension stream are discharged continuously from parcel chamber 12, spread on print platform, form continuous print parcel band.Closing switch valve (A) 25 and switch valve (B) 26, wrapping action stops.
As shown in Figure 7, under interval parcel pattern, hydrogel to active biomaterial with the automatic parcel step of sodium alginate suspension is: the first step is identical with aforesaid continuous parcel pattern to the 5th step, but pressure P 1 is adjusted to 0.40MPa, and pressure P 2 is adjusted to 0.35MPa.6th step, by controller close synchronously switch valve (A) 25 and switch valve (B) 26, stops wrapping action; Under capillary effect, forming certain thickness on the surface of active biomaterial and sodium alginate suspension is the hydrogel layer of 0.90 ~ 0.11mm, form wrapped active biomaterial and sodium alginate suspension microparticle, and discharge from the parcel chamber 12 of ejecting device 29, spread on print platform.The opening time of gauge tap valve (A) 25 and switch valve (B) 26 and closing time interval, synchronous or asynchronous controlling, can form the enwrapped granule band distributed at a certain distance on print platform.
Regulate the difference between pressure P 1 and P2 value and P1 and P2, synchronous or asynchronous controlling are carried out to switch valve (A) 25 and switch valve (B) 26, the velocity of discharge of active biomaterial and sodium alginate suspension stream and the thickness of hydrogel integument can be controlled.
Embodiment two
As shown in Figure 3, this ejecting device is structurally similar with combined jet head unit, but integrated manufacture, comprise central lumen 9, center nozzle 10, circular passage 11, duct (A) 34 and parcel chamber 12.Material is the macromolecular material with biocompatibility, prints manufacture technics with injection molding technique or 3D.Compared with combined jet head unit, be characterized in that whole ejecting device is made up of single component, integral one-step molding, do not need assembling, the size of circular passage 11 can not regulate after shaping.When building automatic baggage systems as shown in Figure 5, in print cartridge (A) 27, loading active biomaterial and sodium alginate suspension, in print cartridge (B) 28, load hydrogel; The outfan of print cartridge (A) 27 is connected with the central lumen 9 on this ejecting device; The outfan of print cartridge (B) 28 is connected with duct 34, can arrange one or more duct (A) 34, is connected bottom duct (A) 34 with circular passage 11.
Its work process is consistent with description in embodiment one.
Embodiment three
As shown in Figure 4, in this ejecting device above-described embodiment two, integrated ejecting device is similar, comprises central lumen 9, center nozzle 10, circular passage 11, parcel circular passage 13, chamber 12, second, duct (A) 34, duct (B) 33 and the second parcel chamber 14.Material is the macromolecular material with biocompatibility, prints manufacture technics with injection moulding or 3D.Compared with the ejecting device of Fig. 4, be characterized on integral one-step molding basis, add circular passage, duct (B) 33, second 13 and the second parcel chamber 14, there is double wrapped function.
Automatic baggage systems and Fig. 5 similar, but configuration 3 print cartridges: No. 1 print cartridge loads active biomaterial and sodium alginate suspension, A kind hydrogel loaded by No. 2 print cartridges, B kind hydrogels loaded by No. 3 print cartridges.Gas circuit, after one-level pressure relief valve and second depressurized valve reduce pressure, is divided into 3 branches by source gas: be connected with No. 1 switch valve after the 1st branch connects No. 1 servo valve, then be connected with No. 1 print cartridge, is finally connected with the central lumen 9 on this ejecting device; Be connected with No. 2 switch valves after 2nd branch connects No. 2 servo valves, then be connected with No. 2 print cartridges, be finally connected with the duct 34 on this ejecting device, and be connected with circular passage 11; Be connected with No. 3 switch valves after 3rd branch connects No. 3 servo valves, then be connected with No. 3 print cartridges, be finally connected with the duct 33 on this ejecting device, and further with the second circular passage 13 is connected.Servo valve in 3 gas circuit branches and switch valve is controlled respectively by controller.
Under continuous parcel pattern, the pressure of setting No. 1, No. 2 and No. 3 servo valve front end is 0.65MPa, the pressure regulating No. 1 print cartridge is 0.60MPa, the pressure of No. 2 print cartridges is 0.55MPa, the pressure of No. 3 print cartridges is 0.50MPa, what describe in its work process and embodiment one is similar, can form continuous print parcel band on print platform.This parcel band is 3 layers: center is active biomaterial and sodium alginate suspension, intermediate layer is A kind hydrogel, skin is B kind hydrogel.
Under interval parcel pattern, the pressure of setting No. 1, No. 2 and No. 3 servo valve front end is 0.65MPa, the pressure regulating No. 1 print cartridge is 0.50MPa, the pressure of No. 2 print cartridges is 0.45MPa, the pressure of No. 3 print cartridges is 0.40MPa, what describe in its work process and embodiment one is similar, can form the two layers of enwrapped granule band distributed at a certain distance on print platform.This enwrapped granule is 3 layers: center is active biomaterial and sodium alginate suspension, intermediate layer is A kind hydrogel, skin is B kind hydrogel.
Although present invention uses fixing head, urceolus, inner core, urceolus through hole, screw hole, fixing head through hole, sealing ring, central lumen, center nozzle, circular passage, parcel chamber, second circular passage, second parcel chamber, source of the gas, one-level pressure relief valve, filter, second depressurized valve, pressure transducer, three way cock, servo valve, pressure transducer, print cartridge, switch valve, controller, ejecting device, active biomaterial, suspension, the terms such as lapping, but do not get rid of the probability of other term, these terms are used to be only used to more describe and explain essence of the present invention, the restriction that they are construed to any one additional is all disagreed with spirit of the present invention.
The present invention is not limited to above-mentioned embodiment, as long as the technical scheme realizing the object of the invention with basic same approach all belongs within protection scope of the present invention.

Claims (6)

1. one kind has the ejecting device of automatic parcel function, comprise inner core (3), urceolus (2), fixing head (1), sealing ring (8), it is characterized in that: there is a stepped inner chamber body on urceolus (2) top, bottom has one to wrap up chamber (12), and lateral surface has a urceolus through hole (4) through with inner chamber body (11); A step is arranged at inner core (3) top, a central lumen (9), and a center of orifices (10) is arranged at bottom; After installing, inner core (3) and urceolus (2) top are in one plane; Fixing head (1) has through hole (7), screw hole A (5) and screw hole B (6) in a thickness direction; First in urceolus (2) stepped inner chamber body, place sealing ring (8), put into inner core (3) again, shoulder hole and the sealing ring (8) of the step on inner core (3) top and urceolus (2) inside form sealing; Fixing head (1) is buckled in the upper surface of inner core (3) and urceolus (2), by screw A (5) and screw hole B (6) screw, fixing head (1), inner core (3) and urceolus (2) is connected as a single entity; The top of inner core (3) central lumen (9) can process female thread to be connected with pipe joint; Be matched in clearance between inner core (3) and urceolus (2), and form certain thickness circular passage (11) between inner core (3) and urceolus (2), and be communicated with the urceolus through hole (4) of urceolus (2) side; It is parcel chamber (12) in the bottom of ejecting device; Be matching relationship between inner core and urceolus, ensure the axiality between center of orifices and parcel chamber, sealing ring prevents the fluid leakage in circular passage.
2. ejecting device according to claim 1, is characterized in that: be matching relationship between inner core and urceolus, guarantee that inner core and urceolus are concentric; The circular passage formed between inner core and urceolus can be circle; Can by the fine setting of axial displacement, the thickness of adjustment circular passage.
3. ejecting device according to claim 1, is characterized in that: the quantity of the circular passage of ejecting device is one or more; All circular passages are all arranged around center of orifices, and the spacing between circular passage is equal or unequal, and the shape of each circular passage is identical or not identical.
4. ejecting device according to claim 1, is characterized in that: be one or more with the through hole quantity of circular passage outside urceolus; Through hole is circumferentially symmetric, or asymmetric distribution.
5. one kind uses the automatic baggage systems of the ejecting device described in any one of claim 1-4, comprise source of the gas (15), one-level pressure relief valve (16), filter (17), second depressurized valve (18), pressure transducer (19), three way cock (20), servo valve A (21), servo valve B (22), pressure transducer A (23), pressure transducer B (24), print cartridge A (27), print cartridge B (28), switch valve A (25), switch valve B (26), ejecting device (29); Source of the gas (15), one-level pressure relief valve (16), filter (17), second depressurized valve (18) and pressure transducer (19) connect successively, are connected respectively by three way cock with servo valve A (21), servo valve B (22); Servo valve A (21) is connected with switch valve A (25), and is connected with the print cartridge A (27) that active biomaterial is housed, and is finally connected with the central lumen (9) on ejecting device (29); Servo valve B (22) is connected with switch valve A (26), and is connected with the print cartridge A (28) that lapping is housed, and is finally connected with the urceolus through hole (4) on ejecting device (29); Controller is by controlling the open and close of switch valve A (25), switch valve B (26), respectively regulating and control is carried out to the pressure in print cartridge A (27), print cartridge B (28), and realize the automatic parcel of lapping to active biomaterial.
6. automatic baggage systems according to claim 5, is characterized in that: lapping and wrapped material can be active biomaterial or nonactive biomaterial.
CN201520289726.1U 2015-05-07 2015-05-07 Shower nozzle device and parcel system with automatically, wrap up function Expired - Fee Related CN204839829U (en)

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CN109153182A (en) * 2016-05-03 2019-01-04 T&R 碧欧法博有限公司 For the method to 3 D-printing supply ink and use the 3 D-printing method of this method
CN106388970B (en) * 2016-11-02 2018-04-13 四川蓝光英诺生物科技股份有限公司 A kind of ejecting device with parcel
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US11724450B2 (en) 2017-03-15 2023-08-15 Aspect Biosystems Ltd. Systems and methods for printing a fiber structure
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