CN204798638U

CN204798638U - Implanted medical instrument's remote monitering system's patient terminal

Info

Publication number: CN204798638U
Application number: CN201520149629.2U
Authority: CN
Inventors: 陈玥; 陈浩; 马伯志; 吕长泉; 郝红伟; 李路明
Original assignee: Tsinghua University; Beijing Pins Medical Co Ltd
Current assignee: Beijing Pinchi Medical Equipment Co ltd
Priority date: 2015-03-16
Filing date: 2015-03-16
Publication date: 2015-11-25
Anticipated expiration: 2025-03-16

Abstract

The utility model relates to an implanted medical instrument's remote monitering system's patient terminal, it includes: patient's customer end, and the external controller of a patient, the external controller of patient with patient's customer end links to each other, wherein, further include an electric physiological signal sensor and a signal acquisition controller, electricity physiological signal sensor is used for gathering patient's electric physiological signal, just the signal acquisition controller will this electricity physiological signal send to patient's customer end. The utility model provides an implanted medical instrument's remote monitering system's patient terminal passes through patient's electric physiological signal is gathered to electricity physiological signal sensor for adopt the remote monitering system monitoring ways at this patient terminal diversified, can realize more comprehensively monitoring the patient.

Description

A kind of patient terminal of long distance control system of implantable medical devices

Technical field

This utility model relates to implantable medical devices field, particularly relates to a kind of long distance control system and method for work thereof of implantable medical devices.

Background technology

In implantable medical devices, nerve stimulator by carrying out chronic electrical stimulation to target nerve, the symptom of effective controlling functions sacred disease and mental sickness.Nerve stimulator and the indication thereof of U.S. FDA approval comprise, brain depth stimulator treatment is trembled, parkinson disease, myodystonia, obsession, vagus nerve stimulator treatment epilepsy, depression, spinal stimulator treatment pain, sacral nerve stimulator treatment urinary incontinence etc.

In the therapeutic process of embedded nerve stimulator, needs of patients regularly goes to hospital to follow up a case by regular visits to after surgery.Play monitoring function on the one hand, namely doctor is by observing the amelioration of disease situation of patient, program control instrument is used to obtain stimulator information, as battery electric quantity, electrode impedance, stimulus parameter etc., play programmable function on the other hand, namely doctor is according to the situation of change of conditions of patients and medication, uses program control instrument adjustment stimulus parameter, thus the curative effect making patient activity better.Usually annual needs of patients several times so that more times ground follow up a case by regular visits to hospital.This increases the weight of handicapped or that residence is remote patient burden, and within the interval of to follow up a case by regular visits to for twice, if embedded nerve stimulator breaks down or stimulus parameter is inappropriate, doctor cannot Timeliness coverage, thus brings risk for patient.

The long distance control system of existing implantable medical devices adopts huge electronic multimedia device usually, needs doctor to observe patient profiles by the angle of remote controller operation photographic head and focal length.The long distance control system of this implantable medical devices monitors patient by means of only audio/video communication, and means are single, there is the problems such as Operating Complexity is high, portability is poor, monitoring is not comprehensive.

Utility model content

In view of this, necessaryly provide a kind of and can make the variation of long distance control system monitoring means and monitor the patient terminal of the long distance control system of more fully implantable medical devices.

This utility model relates to a kind of patient terminal of long distance control system of implantable medical devices, and it comprises: patient customer's end; And a patient body outer controller, described patient body outer controller is held with described patient customer and is connected; Wherein, an electricity physiological signal sensor and a signal acquisition controller is comprised further; Described electricity physiological signal sensor is for gathering the electricity physiological signal of patient, and this electricity physiological signal is sent to described patient customer end by described signal acquisition controller.

Further, described signal acquisition controller comprises: one for the first communication module of described patient customer's end communication, one for the second communication module of a remote monitoring server communication, a microprocessor and a signal acquisition module; Described microprocessor to be connected from this electricity physiological signal sensor by this signal acquisition module and for selecting and controlling the different physiological signal of this electricity physiological signal sensor acquisition.

Further, described signal acquisition controller and described patient body outer controller integrated, described patient body outer controller comprises: one for the first communication module of described implantable medical devices communication, one for the second communication module of described patient customer's end communication, one for the third communication module of a remote monitoring server communication, a signal acquisition module, a microprocessor, a display screen, a button and switch and a power management module; Described microprocessor to be connected from this electricity physiological signal sensor by this signal acquisition module and for selecting and controlling the different physiological signal of this electricity physiological signal sensor acquisition.

Further, described signal acquisition controller also comprises an electricity physiological signal discrimination module be connected with described microprocessor, described electricity physiological signal discrimination module is used for analyzing the electricity physiological signal that this signal acquisition module collects, and classifies according to different risk class.

Further, described electricity physiological signal discrimination module is connected between described microprocessor and this signal acquisition module.

Further, described signal acquisition module comprises a signal input interface, a signal conditioning circuit be connected with this signal input interface and a signal output interface be connected with this signal conditioning circuit; Described signal conditioning circuit is exported by described signal output interface after being used for carrying out stress release treatment and processing and amplifying to the signal collected.

Further, described signal input interface comprises: the selector module that a wired interface module, a radio interface module and are connected with described wired interface module and radio interface module respectively; Described selector module is controlled by described microprocessor, selects data channel, thus realizes the collection to unlike signal.

Further, described signal output interface comprises: an analog to digital conversion circuit and a digital output port be connected with this analog to digital conversion circuit; Described digital output port is connected with described MPI.

Further, described electricity physiological signal sensor is one or more in surface myoelectric electrode, electrocardioelectrode, implanted brain depth electrode, acceleration transducer and electrocardio Holter.

Further, described surface myoelectric electrode, electrocardioelectrode and described signal acquisition controller wired connection; Described implanted brain depth electrode, electrocardio Holter and described signal acquisition controller wireless connections.

Compared with prior art, the patient terminal of the long distance control system of the implantable medical devices that this utility model provides is by the electricity physiological signal of described electricity physiological signal sensor acquisition patient, make the long distance control system monitoring means variation adopting this patient terminal, the monitoring more comprehensively to patient can be realized.

Accompanying drawing explanation

Fig. 1 is the frame diagram of the long distance control system of the implantable medical devices of this utility model first embodiment.

Fig. 2 is the frame diagram of the patient body outer controller of this utility model first embodiment.

Fig. 3 is the frame diagram of the signal acquisition module of the patient body outer controller of this utility model first embodiment.

Fig. 4 is the frame diagram of the patient terminal of this utility model first embodiment.

Fig. 5 be the doctor terminal of this utility model first embodiment frame diagram.

Fig. 6 is the frame diagram of the remote monitoring server of this utility model first embodiment.

Fig. 7 is the frame diagram that this utility model real first executes the remote monitoring website of the remote monitoring server of example.

Fig. 8 is the frame diagram of the senior monitoring module of the remote monitoring server of this utility model first embodiment.

Fig. 9 is the operation principle schematic diagram of the Audio Visual Communication server of this utility model first embodiment.

Figure 10 is the workflow diagram of the implantable medical devices of this utility model first embodiment.

Figure 11 is the frame diagram of the long distance control system of the implantable medical devices of this utility model second embodiment.

Figure 12 be the signal acquisition controller of the long distance control system of the implantable medical devices of this utility model second embodiment frame diagram.

Detailed description of the invention

Below in conjunction with the accompanying drawings and the specific embodiments, the long distance control system of the implantable medical devices that this utility model provides and method of work thereof are described in further detail.The embodiment that accompanying drawing describes is exemplary, only for explaining this utility model, and can not be interpreted as restriction of the present utility model.

Refer to Fig. 1, this utility model first embodiment provides a kind of long distance control system 10 of implantable medical devices 100, and it comprises: implantable medical devices 100, patient body outer controller 200, electricity physiological signal sensor 300, patient customer holds 400, one doctor terminal 500, remote monitoring server 600, data analytics server 700 and an Audio Visual Communication server 800.Wherein, described patient body outer controller 200, described electricity physiological signal sensor 300 He, described patient customer holds 400 jointly to form a patient terminal.

Described implantable medical devices 100 is implanted in patient body when using.Described implantable medical devices 100 can be cardiac pacemaker, defibrillator, lesions located in deep brain device, spinal stimulator, vagus nerve stimulator, the intestines and stomach stimulator or other similar implantable medical devices.This utility model is only described for lesions located in deep brain device.

Described patient body outer controller 200 holds 400 to be connected with described implantable medical devices 100 with described patient customer respectively, and can 400 be held to carry out two-way communication with implantable medical devices 100 and patient customer and export data or instruction.Described patient body outer controller 200 is connected with described electricity physiological signal sensor 300 by wired or wireless mode.When the operation conditions crisis of implantable medical devices 100, described patient body outer controller 200 meeting automatic discrimination risk class, and differentiation result data is sent to described remote monitoring server 600.

As shown in Figure 2, described patient body outer controller 200 comprises first communication module 210, second communication module 220, third communication module 230, signal acquisition module 240, microprocessor 250, display screen 260, button and switch 270 and power management module 280, electricity physiological signal discrimination module 290.

Described first communication module 210 is connected with described implantable medical devices 100 is wireless, for receiving the operation conditions of described implantable medical devices 100 and forwarding instruction to described implantable medical devices 100.Described second communication module 220 holds 400 to be connected with described patient customer, for receiving the instruction that described patient customer holds 400, and holds the described running status of implantable medical devices 100 of 400 forwarding and the electric physiological data of patient to described patient customer.Described third communication module 230 is connected with described remote monitoring server 600, for giving described remote monitoring server 600 by report the test higher for risk identification result.Described signal acquisition module 240 is connected with described electricity physiological signal sensor 300, for gathering the electricity physiological signal of patient and sending to described microprocessor 250.Described signal acquisition module 240 specifically can the electricity physiological signal such as collection surface myoelectricity, electrocardio, the brain deep signal of telecommunication, but has more than to be limited to and gather these signals.Described microprocessor 250 is control cores of described patient body outer controller 200, mainly comprises two kinds of mode of operations: the autonomous shaping modes of patient and doctor's remote monitoring pattern.Described microprocessor 250 is provided with command input, the parameters input end of each toggle switch, electricity physiological signal input, the long distance control system data input and output end that each control button exports.Described microprocessor 250 is connected with described first communication module 210, described second communication module 220, described third communication module 230, described signal acquisition module 240, display screen 260 and button and switch 270 respectively, and controls it.Each ingredient of described patient body outer controller 200 all works in the coordination of described microprocessor 250 with under controlling, and realizes controlling people and mutual, setting communication protocol, and modulate, the function such as demodulation communication data.

Further, described patient body outer controller 200 also comprises an electricity physiological signal discrimination module 290.Described microprocessor 250 is connected with this electricity physiological signal discrimination module 290.Preferably, described electricity physiological signal discrimination module 290 is connected between described microprocessor 250 and this signal acquisition module 240.Described electricity physiological signal discrimination module 290 simply can be analyzed the electricity physiological signal that this signal acquisition module 240 collects, and classifies according to different risk class.When risk class is lower, described microprocessor 250 sends data to described patient customer by described second communication module 220 and holds 400, then holds 400 to be sent to described remote monitoring server 600 through described patient customer.When risk class is higher, described microprocessor 250 directly sends data to described remote monitoring server 600, so that doctor processes in time by described third communication module 230.Such as, calculate rhythm of the heart data by described electricity physiological signal discrimination module 290 pairs of electrocardiosignaies, if namely rhythm of the heart overrun is reported to described remote monitoring server 600.

As shown in Figure 3, described signal acquisition module 240 comprises the signal output interface 243 that signal conditioning circuit 242, that a signal input interface 241, is connected with this signal input interface 241 is connected with this signal conditioning circuit 242.Described signal input interface 241 comprises a wired interface module 2411, one radio interface module 2412 and a selector module 2413 be connected with described wired interface module 2411 and radio interface module 2412 respectively, wherein, described wired interface module 2411 is for receiving surface electromyographic electrode 301, the wired input of electricity physiological signal of sensor such as electricity physiological signal such as electrocardioelectrode 302 grade 300, described radio interface module 2412 is for receiving brain depth electrode 303 and discharger 304 thereof, the radio physiological signal of the wireless launcher transmitting of the electricity physiological signal sensors 300 such as electrocardio Holter305.That is, described surface myoelectric electrode, electrocardioelectrode and described patient body outer controller 200 wired connection; Described implanted brain depth electrode, electrocardio Holter305 and the wireless connections of described patient body outer controller 200.Described selector module 2413 is controlled by described microprocessor 250, selects data channel, thus realizes the collection to unlike signal.Described signal conditioning circuit 242 is exported by described signal output interface 243 after carrying out stress release treatment and processing and amplifying to the signal collected.Described signal output interface 243 comprises an analog to digital conversion circuit 2431 and a digital output port 2432 be connected with this analog to digital conversion circuit 2431.Described digital output port 2432 is connected with described microprocessor 250 interface.Described electric physiological data is forwarded to described second communication module 220 via described microprocessor 250, holds 400 to transfer to described remote monitoring server 600 eventually through described patient customer.

In an embodiment of the present utility model, described first communication module 210 regularly communicates with described implantable medical devices 100, obtains the operation conditions of described implantable medical devices 100.According to the operation conditions of described implantable medical devices 100, described microprocessor 250 judges that the operation conditions of described implantable medical devices 100 has and do not have obvious abnormal conditions.When the operation conditions of described implantable medical devices 100 is less than obvious exception, sends to described patient customer to hold 400 health data by described second communication module 220, then hold 400 to be sent to described remote monitoring server 600 by described patient customer.When there is obvious exception or run into accident in the operation conditions of described implantable medical devices 100; attribute and the rank of this event is judged by the program in described microprocessor 250; if belong to emergency; then immediately data are sent to described remote monitoring server 600 by described third communication module 230, and are sent to described doctor terminal 500 by this remote monitoring server 600.

In an embodiment of the present utility model, described patient body outer controller 200 and described implantable medical devices 100 carry out two-way reliable communication, signalling channel can adopt the analogue modulation system such as amplitude modulation(PAM), frequency modulation(PFM), also can adopt the digital modulation modes such as amplitude-shift keying ASK, frequency shift keying fsk, pulse position modulation PPM.Described second communication module 220 integrated data links interface, as described patient customer hold 400 with the communication terminal of described implantable medical devices 100, receive the instruction of to hold 400 from described patient customer.Same/the wire communication such as Asynchronous Serial Interface, usb bus mode can be adopted to realize, the communication such as bluetooth, satellite also can be adopted to realize.The communication mode of described third communication module 230 adopts communication, such as, and the wireless network communication services that WLAN WLAN, general packet radio service GPRS, global intercommunication microwave access WiMAX, G mobile Communication network 3G etc. is similar.Described patient body outer controller 200 upgrades communication key by described third communication module 230 with described remote monitoring server 600 direct wireless communication.

The kind of described electricity physiological signal sensor 300 is not limit, and can be one or more in surface myoelectric electrode, electrocardioelectrode, implanted brain depth electrode, acceleration transducer, electrocardio Holter etc.Described electricity physiological signal sensor 300 is for measuring the electricity physiological signal of patient in long distance monitoring process.In patients with implantation body, also can be able to be arranged at outside patient body when described electricity physiological signal sensor 300 uses.Such as, when described implanted brain depth electrode uses in patients with implantation body, when described surface myoelectric electrode uses, be arranged at patient body-surface.

Described patient customer holds one end of 400 other end that is connected with described patient body outer controller 200 to be connected with described Audio Visual Communication server 800 with described remote monitoring server 600 respectively.Described patient customer holds 400 the health data of the medical apparatus and instruments 100 received to be sent in described remote monitoring server 600, and sends the audio-visual data of patient to Audio Visual Communication server 800, receives the audio-visual data of doctor simultaneously.

Refer to Fig. 4, described patient customer holds 400 to comprise microprocessor 410, identity certified component 420, remote monitoring assembly 430, communications component 440, audio frequency and video assembly 450, audio-video acquisition equipment 460 and a power module 470.

Described microprocessor 410 is as the control core of patient customer's terminal 400, and the assembly of all doctor's monitor clients all works in the coordination of described microprocessor 410 with under controlling.Described authentication assembly 420 is for carrying out safe certification to patient, and it comprises a patient identity authentication module and a physicianship authentication module.Described patient identity authentication module is for examining the identity of operator, and patient, after described authentication assembly input user identification code (ID) and password, carries out senior certification.The authentication methods such as described senior certification can be digital signature, digital certificate, identity card or smartcard identification, short message password, dynamic password, USB escape, bio-identification (as speech recognition, fingerprint recognition etc.).After above-mentioned a certain or some senior certification, patient identity certification completes.Described physicianship authentication module is for inquiring about described remote monitoring server 600 data base, and the patient to certification provides doctor's state of certification.Patient can initiate remote monitoring request to the doctor by authentication, set up remote monitoring and connect, enter remote monitoring assembly, while carrying out audio video interactive with doctor, receive remote monitoring by doctor after being agreed to.The mode that this example adopts digital certificate and short message password to combine carries out high-level identity certification, and described patient customer holds 400 needs to provide legal digital certificate and effective short message password just by checking to described remote monitoring server 600.

Described remote monitoring assembly 430, for providing long distance monitoring and programmable interface for patient, under the control of described microprocessor 410, is connected with Audio Visual Communication server 800 with described remote monitoring server 600 by described communications component 440.Described remote monitoring assembly 430 provides operating equipment and the visual image operation interfaces such as display screen, button or keyboard.After doctor sends remote monitoring instruction by doctor terminal 500, be forwarded to described patient customer by described remote monitoring server 600 and hold discrimination instruction type in the remote monitoring assembly 430 of 400, such as: the instruction of implantable medical devices 100 state-detection, parameter programming instructions, patient electrophysiological's data acquisition instructions etc.According to different instruction types according to the protocol packing of arranging with patient body outer controller 200, and be forwarded to described patient body outer controller 200 by the Local Communication Module of described communications component 440.Described patient body outer controller 200 communicates after instructions parse with described implantable medical devices 100 or described electricity physiological signal sensor 300, completes the execution of instruction.Instruction execution result is forwarded to described remote monitoring assembly 430 by described communication module 440, presents on a display screen with the interface form of close friend.Duty, patient electrophysiological's data or Parameter Programming result that described remote monitoring assembly 430 obtains communicating further transfer to described remote monitoring server 600 by the network communication module of communications component 440 and check for doctor.Described remote monitoring assembly 430 mainly comprise graphic software platform implantable medical devices 100 operational factor and state, reception remote monitoring instruction, call Patient control and perform the remote monitoring correlation function such as instruction, uploading instructions execution result, be the leitungskern of remote monitoring patient terminal.

Described communications component 440, as the communication interface of patient's remote monitoring terminal, comprises encrypting module and communication module.Encrypting module is used for for the data of all transmissions through described communications component are encrypted, can be symmetric encipherment algorithm or asymmetrical encryption algorithm, this example adopts RSA asymmet-ric encryption method to be encrypted the data being about to be sent to described remote monitoring server 600, and encryption key is by network communication module and remote monitoring server periodic synchronization.Described communication module comprises network communication module and Local Communication Module, wherein, network communication module is connected with remote monitoring server, audio/video communication server by wired or wireless mode, and network schemer can be any one access way of LAN, Metropolitan Area Network (MAN), wide area network, the Internet, wireless broadband network, WLAN WLAN, general packet radio service GPRS, the similar network communication services of global intercommunication microwave access WiMAX, G mobile Communication network 3G, forth generation mobile radio communication 4G etc.This example adopts Broadband Network Access.Local Communication Module is connected with described Patient control by wired or wireless mode, safeguard the exchanges data between described patient customer end and Patient control, the communication modes such as same/step serial line interface, general-purpose serial bus USB or bluetooth can be adopted to realize, and this example adopts bluetooth 4.0 communication mode.

Described audio frequency and video assembly 450 is for setting up real-time audio/video communication with doctor.Described audio frequency and video assembly 450 shares display screen and button with described remote monitoring assembly 430, carries speaker and 3.5mm earphone interface (with reference to international standard CTIA or national standard OMTP).Patient initiates video communication request by audio frequency and video assembly 450 to described audio/video communication server 800, doctor receives request by click keys and gives a response, described audio/video communication server 800 is set up and is carried out two-way communication and generate identify label after requesting party and recipient agree to, audio frequency and video assembly 450 adopts the audio/video communication agreement of P2P or server forwarding (as rtmp afterwards, rimfp, SIP, H.264), audio/video communication real-time in remote monitoring process is carried out with doctor, different video resolutions can be selected according to network condition in communication process, have three gears available: high definition 720p, SD 480p, smooth 320p.

Described audio-video acquisition equipment 460, for catching the Voice & Video of doctor, supplies described audio frequency and video component call.In this example, this equipment can be the cam device of portable digital photographic head (as resolution 640px*480px, interface mode USB2.0), portable computer integrated digital camera or intelligent terminal.Cell voltage voltage stabilizing is 5V by described power management module 470 is described microprocessor 410 and each assembly power supply, boosts as 9V is that described communications component 440 is powered, and control charging be input as battery charging.In this example, described patient customer holds the UI of 400 to show and operation controls by the special Winform client software operated in microprocessor 410, adopts .NetFramework4.0 exploitation.

Described doctor terminal 500 is connected with described Audio Visual Communication server 800 with described remote monitoring server 600 respectively.Described doctor terminal 500 receives and monitors the operation conditions of described implantable medical devices 100, obtain electricity physiological signal and the data results of patient, also send the audio-visual data of doctor to described Audio Visual Communication server 800, receive the audio-visual data of patient simultaneously.

Refer to Fig. 5, described doctor terminal 500 comprises microprocessor 510, identity certified component 520, remote monitoring assembly 530, communications component 540, audio frequency and video assembly 550, audio-video acquisition equipment 560 and a power module 570.

Described microprocessor 510 is as the core of doctor terminal 500, and the assembly of all doctor's monitor clients all works in the coordination of described microcontroller 510 with under controlling.Described authentication assembly 520 for carrying out safe certification to doctor, and limits the authority of different doctor according to authentication result, and its composition comprises physicianship authentication module and patient identity authentication module.Physicianship authentication module is for examining the identity of operator, and doctor, after authentication assembly input user identification code (ID) and password, carries out senior certification.In the present embodiment, the senior authentication mode that authentication assembly adopts digital certificate to be combined with short message password, digital certificate is issued by described remote monitoring server 600, described doctor terminal 500 only has have been installed legal digital certificate and could access described remote monitoring server 600, in the mobile phone that short message password is sent to doctor by described remote monitoring server 600 or other intelligent movable equipment.

According to the difference of authentication result, remote monitoring assembly is by the operating right of restriction doctor.In this example, elementary monitoring doctor (as clinical assistant director, nurse) can only use the elementary monitoring module in remote monitoring assembly 530..Senior monitoring doctor (as neurosurgery expert, the doctor in charge etc.) can use the elementary and senior monitoring module of remote monitoring assembly 530.In addition, the doctor of authentication result restriction different stage is responsible for the Patient list of different range, and in this example, the doctor of program control head center can all patients of being responsible for of this center program control, and subcenter doctor can only the administrative patient of program control distribution.

In embodiment of the present utility model, a corresponding multidigit patient of senior doctors, when wherein having patient or have the senior monitoring of multidigit patient admission, medical practitioner can select the request of an agreement patient, and could agree to the connection request of next bit patient after can only disconnecting in the connection with current patents.After agreeing to connection, record the patient of this medical practitioner current monitor in the data base of described remote monitoring server 600, after successful connection, page jump is to senior monitoring module.

Described remote monitoring assembly 530, for providing long distance monitoring and programmable interface for doctor, under the control of described microprocessor 510, is connected with described remote monitoring server 600 by described communications component 540.Described remote monitoring assembly 530 provides operating equipment, the visual image operation interfaces such as display screen, button or keyboard, for doctor provides remote monitoring activities interface.Remote monitoring module comprises elementary monitoring module and senior monitoring module.Elementary monitoring module is used for carrying out simple status poll function (as remote measurement, battery electric quantity inquiry, patient information inquiry etc.) to its implantable medical devices 100.

In an embodiment of the present utility model, feldsher shows all pending events after entering elementary monitoring module, and feldsher processes event according to the urgency level (urgency level is identical, according to time sequencing) of event.For the event that urgency level is higher, such as, implantable medical devices running parameter overrun, patient electrophysiological's data overrun etc., feldsher sends the instruction of shutting down or starting secure operating mode immediately to patient terminal.The elementary monitoring request of patient is processed by feldsher as a kind of event, comprises the groundwork status poll to implantable medical devices, regular maintenance suggestion, charge reminder, the prompting of replacing battery, security key update etc.For the lower event of urgency level, such as, the work report that the outer programmable device of patient body is submitted on schedule, feldsher can according to working specification, analytical work report, suggestion patient whether change battery or the need of charging, the need of carrying out senior monitoring etc.Described senior monitoring module for showing the patient information of medical practitioner, to implantable medical devices 100 carry out complicated program control, patient electrophysiological's data are read and are analyzed, its detailed functions will illustrate in fig. 8.

In this example, the operation logic of described authentication assembly 520 and described remote monitoring assembly 530, data structure and interface display all have the ASP website being erected at remote monitoring server inside to control, and this website adopts the MVC three-tier architecture of .NetFrameworks4.0.Described doctor terminal 500 carries out authentication, the operation of remote monitoring and the inquiry of data and typing by browser.

Described audio frequency and video assembly 550 is for setting up real-time audio/video communication with patient.Described audio frequency and video assembly 550 can share display screen and button with described remote monitoring assembly 530, carries speaker and 3.5mm earphone interface (with reference to international standard CTIA or national standard OMTP).Patient initiates video communication request by the audio frequency and video assembly 550 with similar functions to described audio/video communication server 800.Described audio frequency and video assembly 550 calls the communication request of described communications component 540 from server acquisition patient by microprocessor, doctor receives request by click keys and gives a response, described audio/video communication server 800 is set up and is carried out two-way communication and generate identify label after requesting party and recipient agree to, the audio frequency and video assembly 550 audio/video communication agreement (as rtmp, rimfp, SIP, H.264) that adopts P2P or server to forward, carries out audio/video communication real-time in remote monitoring process with patient afterwards.

Described audio frequency and video assembly 550 has video record, upload function, the video record of patient in programme can be uploaded to described remote monitoring server 600, preserve as patient medical record data.Described audio frequency and video assembly 550 also has video communication Media Stream and controls, doctor can according to network condition, select to carry out the communication of high-resolution bidirectional audio-video, the communication of SD bidirectional audio-video, smooth bidirectional audio-video communication, the bidirectional audio communication of reception patient video and only bidirectional audio communication between doctors and patients, in this example doctor send the communication of video high-resolution resolution be 720p, Standard Definition resolution is 480p, and smooth resolution is 320p.In this example, the user interface (UI) of described audio frequency and video assembly 550 is run graphical operation software in the microprocessor, operation push-button and video display windows such as having adjustment definition, connect doctor, disconnect.In this example, described audio frequency and video component software part adopts WebRTC framework, communicates based on WHATWG agreement.Described audio-video acquisition equipment 560, for catching the Voice & Video of doctor, calls for described audio frequency and video assembly 550.In this example, this equipment can be the cam device of portable digital photographic head (as resolution 640px*480px, interface mode USB2.0), portable computer integrated digital camera or intelligent terminal.

Described communications component 540, as the communication interface of described doctor terminal 500, is bi-directionally connected with described microprocessor 510, realizes this doctor terminal 500 and transmits with the data of described remote monitoring server 600, described audio/video communication server 800.Described communications component 540 comprises encrypting module and communication module: encrypting module is used for for the data of all transmissions through described network communication components are encrypted, adopt hardware encryption circuit and coordinate microprocessor to calculate and realize encryption, encryption method can be symmetric cryptography or asymmetric cryptosystem, encryption key and server periodic synchronization; Communication module comprises wire communication module and wireless communication module, can pass through any one access to remote monitoring server of LAN, Metropolitan Area Network (MAN), wide area network, the Internet, wireless broadband network, WLAN WLAN, general packet radio service GPRS, the similar network communication services of global intercommunication microwave access WiMAX, G mobile Communication network 3G, forth generation mobile radio communication 4G etc.Cell voltage voltage stabilizing is 5V by described power management module 17 is described microprocessor 510 and each assembly power supply, boosts as 9V is that described communications component 540 is powered, and control charging be input as battery charging.

Described remote monitoring server 600 building database stores relevant information, such as, and SQLServer, MySQL, XML file etc.One end of described remote monitoring server 600 holds 400 to be connected with described patient customer, and the other end is connected with described doctor terminal 500.Described remote monitoring server 600 is directly connected with described patient body outer controller 200, directly can obtain the operation conditions of described implantable medical devices 100 from described patient body outer controller 200, and obtains the relevant electric physiological data of patient.When described patient body outer controller 200 is in the situation that estimate of situation is critical, report, so that doctor reacts faster directly to described remote monitoring server 600.

Described remote monitoring server 600 is also connected with described data analytics server 700, and and carries out exchanges data between described data analytics server 700.Described data analytics server 700 is for carrying out online or off-line analysis to the electric physiological data of patient, utilize the analytical methods such as linear analysis, nonlinear analysis and machine learning, draw the assessment result with reference significance, and push to described doctor terminal 500.Described linear analysis comprises amplitude analysis, frequency analysis, power spectrumanalysis, wavelet transformation analysis etc.Described nonlinear analysis comprises statistical analysis, chaology analysis etc.Described machine learning comprises svm classifier, neural computing etc.In an embodiment of the present utility model, described data analytics server 700 is analyzed for the epidemiology to patient, clinical data, the method of machine learning and artificial intelligence is adopted to add up the health status of patient, the specificity of described implantable medical devices 100 and assess, draw the assessment result with reference significance, push to doctor terminal 500.

In an embodiment of the present utility model, described data analytics server 700 adopts Microsoft WCF framework, and is connected by LAN with described remote monitoring server 600.When doctor's Water demand, the calculating interface of described data analytics server 700 is called by described remote monitoring server 600, to described data analytics server 700 transmitting data information, obtain result of calculation, and this result of calculation is presented on described doctor terminal 500.

In an embodiment of the present utility model, described audio/video communication server 800 is for maintaining the video communication between doctor and patient in remote monitoring process.Described audio/video communication server 800 is made up of signal server and forwarding server.Described signal server has the algorithm of Firewall Traversing, as STUN crossing technology, ALG crossing technology etc., the audio frequency and video assembly of 400 can be held to carry out NAT when connecting pass through described doctor terminal 500 and described patient customer.Described audio/video communication server 800 is preferentially attempted when selecting connected mode being held between Audio Visual Communication assembly 430 at described doctor's client audio video communication assembly 530 and patient customer by signal server setting up point to point connect and Firewall Traversing.If be successfully established, then audio, video data directly transmits between two audio frequency and video assemblies, forwards without server.If set up unsuccessfully, as fire wall blocks or other reasons, then attempt being transmitted by the transfer of forwarding server as video communication data.In an embodiment of the present utility model, audio/video communication mode can make point-to-point or server forward, and host-host protocol can be rtmp, rimfp, SIP, H.264 etc.;

In an embodiment of the present utility model, support that described doctor terminal Audio Visual Communication assembly 530 carries out video record to carrying out long-range program control patient, and be uploaded to remote monitoring server, preserve as patient electronic medical record's data.

As shown in Figure 6, described remote monitoring server 600 comprises processor 610, memory device 620, network interface 630, wireless network card 640 and a gsm module 650.Described processor 610 is for the program of operation remote monitoring website.Described memorizer 620 is for the data of save routine and doctor, patient and described implantable medical devices 100.Described network interface 630 for hold for described patient customer 400 and doctor terminal 500 communication interface is provided.Described wireless network card 640 provides communication interface for the treatment of device and described patient body outer controller 200.Described gsm module 650 sends message for giving the mobile communication equipment of patient or doctor.

In an embodiment of the present utility model, described doctor terminal 500 and described patient customer hold 400 to access described remote monitoring server 600 respectively by network interface 630, and utilize respective client to visit described remote monitoring server 600.When described implantable medical devices 100 occurs abnormal, the health data of described implantable medical devices 100 is sent to described remote monitoring server 600 by described wireless network card 640, processes in time.When patient or doctor are not online, the mobile communication equipment by described gsm module 650 request of requesting party being sent to Requested Party carries out data interaction.

In an embodiment of the present utility model, described doctor terminal 500, described patient customer hold 400 to adopt certain network security technology to ensure communication safety with described remote monitoring server 600, such as, connected by virtual private net vpn tunneling technology, can the agreements such as LTF, LT2F, SSL be adopted in transportation level.In an embodiment of the present utility model, remote monitoring website adopts MVC three-tier architecture to realize, be responsible for data base read-write by M (Model) layer, V (View) layer is responsible for Pages Design, and C (Control) layer is responsible for website logic control.In an embodiment of the present utility model, remote monitoring website is realized by express network, can use LAN, Metropolitan Area Network (MAN), wide area network and the Internet any one.The host access accepting afterwards to be connected on consolidated network is issued in remote monitoring website on network, and website orientation can adopt Website server releasing software to realize, such as Apache, IIS, NetBox etc.

As shown in Figure 7, described remote monitoring website comprises login module 611, reservation module 612, patient information module 613, feldsher's information module 614, medical practitioner information module 615, elementary monitoring module 616 and a senior monitoring module 617.Described login module 611, for checking the identity of login user according to the storage information of patient in data base and doctor, is checked patient and doctor successfully and is entered respective information module respectively.Described reservation module 612 is preengage before remote monitoring for doctor and patient.In this example, if needs of patients accepts conventional remote monitoring, then send reserve requests in reservation module in advance, designated doctor information and monitoring mode is contained, after doctor receives request, if agree to reservation in request, then both sides have arranged, and can carry out remote monitoring in the designated time.Described patient information module 613 is carried out audio video interactive for patient logs's remote server and doctor and obtains monitor and detection.

In an embodiment of the present utility model, page display personal patient information after patient logs's success, and whether the medical practitioner detecting patient is online.If display medical practitioner present offline, then patient cannot accept senior monitoring, and patient can select to ask elementary monitoring or the mobile communication equipment directly to medical practitioner, such as, as mobile phone, palm PC etc. send information.When patient selects to send request to the mobile communication equipment of medical practitioner, then this request is sent information to terminal or the mobile device of medical practitioner by the gsm module 650 of described remote monitoring server 600.Medical practitioner by replying message to described remote monitoring server 600, can inform that patient responds.If medical practitioner is online, then patient directly can initiate senior monitoring request and connects, and now patient information module enters wait instruction state, if there is program control command, then calling interface performs instruction.Simultaneously, described patient body outer controller 200 starts the electricity physiological signal of the demand collection patient according to medical practitioner, comprise the surface myoelectric of patient, electrocardio and the brain deep signal of telecommunication, these data hold 400 to be sent to described remote monitoring server 600 by described patient customer together with the return data of described implantable medical devices 100.

Described feldsher's information module 630 processes the patient that system is distributed for feldsher.In an embodiment of the present utility model, the state that feldsher registers oneself by operation interface on described remote monitoring server 600 is as in work, described remote monitoring server 600 distributes certain pending event to feldsher, thus enters elementary monitoring module.Described medical practitioner information module 640 for showing the patient information of medical practitioner, and carries out audio video interactive to patient.

In an embodiment of the present utility model, described medical practitioner information module 614 refreshes the online situation of patient that this doctor is responsible for, access the data base of described remote monitoring server 600 simultaneously, obtain the name of patient, whether online, whether initiate the information such as senior monitoring request.

In embodiment of the present utility model, a corresponding multidigit patient of medical practitioner.When wherein having patient or have the senior monitoring of multidigit patient admission, medical practitioner can select the request of an agreement patient, and could agree to the connection request of next bit patient after can only disconnecting in the connection with current patents.After agreeing to connection, record the patient of this medical practitioner current monitor in the data base of described remote monitoring server 600, after successful connection, page jump is to senior monitoring module 616.Described senior monitoring module 616 is for carrying out advanced remote monitoring to described implantable medical devices 600.

In an embodiment of the present utility model, feldsher shows all pending events after entering described elementary monitoring module 615.Feldsher processes event according to the urgency level (urgency level is identical, according to time sequencing) of event.For the event that urgency level is higher, such as, described implantable medical devices 100 running parameter overrun etc., feldsher sends the instruction of shutting down or starting secure operating mode immediately to described patient body outer controller 200.The elementary monitoring request of patient is processed by feldsher as a kind of event, patient can accept the elementary monitoring of feldsher, comprises the groundwork status poll to implantable medical devices, regular maintenance suggestion, charge reminder, the prompting of replacing battery, security key update etc.For the lower event of urgency level, such as, the work report that described patient body outer controller 200 is submitted on schedule, feldsher can according to working specification, analytical work report, suggestion patient whether change battery or the need of charging, the need of carrying out senior monitoring etc.

In an embodiment of the present utility model, feldsher carries out security maintenance by described elementary monitoring module 615 to described patient body outer controller 200, upgrades the communication key of described patient body outer controller 200 and described remote monitoring server 600.Feldsher is sent to described remote monitoring server 600 by needing the information (patient is without the need to logging in remote monitoring server) of informing patient by described doctor terminal 500, and information is sent to the mobile communication equipment of patient by remote monitoring by described gsm module 650.

Described senior monitoring module 617 carries out program control to described implantable medical devices 100 for the health data of the patient of medical practitioner being carried out to audio frequency and video friendship, transmission telemetry command obtains described implantable medical devices 100, transmission program control command and obtains the real-time electricity physiological signal of patient.

As shown in Figure 8, described senior monitoring module 617 comprises original electric physiological data module 6171, electric physiological data analysis module 6172, monitoring running state module 6173, operational factor programming module 6174 and a monitoring parameter and patient's states and inquires about/preserve module 6175.Described original electric physiological data module 6171 holds the original electricity physiological signal of 400 collections for showing described patient customer.Described electric physiological data analysis module 6172 is for calling the calculating interface of described data analytics server 700, utilize the electric physiological data of the analytical patients such as linear analysis, nonlinear analysis and machine learning, and will be presented in face of doctor to the analysis result of patient electrophysiological's data, help the symptom of doctor's assess patient in long-range programme.Described electric physiological data analysis module 6172 calls the calculating interface of described data analytics server 700, utilize the flow process of patient disease to learn statistical data, clinical data etc. and carry out expert estimation, the health status of assess patient and the specificity of described implantable medical devices 100, result is presented in face of doctor, helps doctor to realize personalized therapeutic scheme.Described monitoring running state module 6173 is for showing the current operating conditions of described implantable medical devices 100, medical practitioner enters this senior monitoring module 617 and patient and sets up after video is connected, and to be taken remote measurement the current operating parameters of the implantable medical devices 100 that can obtain in patient body and state by this senior monitoring module 617.Described operational factor programming module 6174 sends program control command for implantable medical devices 100 distally, comprises the programming instructions such as optimum configurations, information setting, mode of operation setting, clock check and correction.Module 6175 is inquired about/preserved to described monitoring parameter and patient's states for providing the interface of electronic health record data base querying/storage, and doctor inquires about/preserve module 6175 by this monitoring parameter and patient's states can inquire about patients symptomatic's order of severity under the program control parameter of patient history and this parameter or improvement degree.Described monitoring parameter and patient's states inquire about/preserve module 6175 long-range program control in can preserve the patients symptomatic of the combination of described implantable medical devices 100 a certain running parameter and correspondence thereof at any time.Such as, in this example, doctor can inquire about/preserve module 6175 by this monitoring parameter and patient's states and inquire about the program control parameter of history (amplitude, frequency, pulsewidth etc.) of described embedded nerve stimulator 100 and the patients symptomatic of correspondence thereof, and preserves new program control record.

As shown in Figure 9, described patient terminal's audio-visual data collecting device 420 catches local sound and image, be presented in appointed area, and described patient terminal's Audio Visual Communication assembly 430 is connected to described Audio Visual Communication server 800 by IP address, send point-to-point protocol connection request, after successful connection, obtain the ID returned by described Audio Visual Communication server 800, as the identify label communicated with other-end.Equally, doctor terminal audio-visual data collecting device 520 catches local sound and image, be presented in appointed area, and described doctor terminal Audio Visual Communication assembly 530 is connected to described Audio Visual Communication server 800 by IP address, send point-to-point protocol connection request, after successful connection, obtain the ID returned by described Audio Visual Communication server 800, as the identify label communicated with other-end.Local audio video flowing issued by described patient terminal's Audio Visual Communication assembly 430 on network, described doctor terminal Audio Visual Communication group 530 subscription is waited for as publisher, doctor terminal Audio Visual Communication assembly 530 obtains the identify label ID of publisher, and then subscribes to the audio and video streams of publisher.Described doctor terminal Audio Visual Communication assembly 530 issues oneself audio frequency and video stream information while subscribing on network, and described patient terminal's Audio Visual Communication assembly 530 is oppositely subscribed to, subscribe to the audio and video streams of doctor, realize two-way Audio Visual Communication, after connection setup success, described Audio Visual Communication server 800 does not have the transfer of data, and the data of Audio Visual Communication are directly transmitted between each Audio Visual Communication assembly.

Described patient customer hold 400 and the audio-visual data collecting device of described doctor terminal 500 catch sound and image, described patient customer hold 400 and the Audio Visual Communication assembly of described doctor terminal 500 be connected respectively to described Audio Visual Communication server 800, patient and doctor carry out Audio Visual Communication by Audio Visual Communication assembly.

The long distance control system 10 of the implantable medical devices 100 of this utility model embodiment, owing to being integrated with electricity physiological signal sensor 300 and data analytics server 700, the electricity physiological signal of patient can be gathered by this electricity physiological signal sensor 300, and by this data analytics server 700 analyzing and processing is carried out to the electricity physiological signal collected and analysis result is sent to doctor's reference.Therefore, this long distance control system 10 is simple to operate, monitoring means variation, more comprehensive to the monitoring of patient.

Introduce the method for work of the long distance control system 10 of the implantable medical devices 100 of this utility model embodiment below.Be appreciated that this utility model embodiment only introduces this long distance control system 10 method of work relevant with this electricity physiological signal sensor 300.

See Figure 10, the method for work of the patient body outer controller 200 of long distance control system 10 of the present utility model comprises the following steps:

Step S10, judges whether to receive the handshake of to hold 400 from patient customer in a very first time threshold value, if so, then enters step S11, if not, then enter step S19;

Step S11, sends answer signal, and enters step S12;

Step S12, judges whether to receive instruction in one second time threshold, if so, then enters step S13, if not, then enter step S19;

Step S13, decision instruction type, if messaging parameter arranges instruction, then enters step S14; If electricity physiological signal acquisition instructions, then enter step S15; If long-range program control command, then enter step S16; If halt instruction, then directly enter step S19;

Step S14, arranges messaging parameter, holds 400 transmission result of communication and return step S12 to described patient customer;

Step S15, gathers electricity physiological signal, the above-mentioned electricity physiological signal collected is sent to described remote monitoring server 600, and returns step S12;

Step S16, judges that whether checking command is legal, if yes then enter step S17, if otherwise return step S12;

Step S17, sends instruction to described implantable medical devices 100 and enters step S18;

Step S18, obtains program control result, this program control result is sent to described remote monitoring server 600, and returns step S12; And

Step S19, instruction communication failure also terminates communication.

In described step S10, described in judge whether that in very first time threshold value, receive handshake refers to judge whether described second communication module 220 receives the handshake that described patient customer holds 400.Described very first time threshold value can set as required.In the present embodiment, described very first time threshold value is 5 minutes.

In described step S11, described transmission answer signal refers to hold 400 transmission answer signals by described second communication module 220 to described patient customer.

In described step S12, described in judge whether that in the second time threshold, receive instruction refers to judge whether described second communication module 220 receives the instruction that described patient customer holds 400.Described second time threshold can set as required.In the present embodiment, described second time threshold is 20 seconds.

In described step S13, the step of described decision instruction type is undertaken by this microprocessor 250.

In described step S14, the described messaging parameter that arranges refers to arrange described patient body outer controller 200 and described patient customer and holds messaging parameter between 400, such as communication pattern, baud rate, verification mode, master slave mode, wake-up mode, transmitting power, park mode etc.

In described step S15, described collection electricity physiological signal refers to that described signal acquisition module 240 gathers the electricity physiological signal of patient by described electricity physiological signal sensor 300.The described step S15 above-mentioned electricity physiological signal collected being sent to described remote monitoring server 600 is further comprising the steps:

Step S151, is simply analyzed the electricity physiological signal collected by its electricity physiological signal discrimination module 290, classifies according to different risk class;

Step S152, when risk class is lower, sends data to described patient customer by described second communication module 220 and holds 400, then holds 400 to be sent to described remote monitoring server 600 through described patient customer; And

Step S153, when risk class is higher, directly sends data to described remote monitoring server 600, so that doctor processes in time by described third communication module 230.

Described risk class can be arranged as required.Such as: the setting rhythm of the heart is continued above normal range 5%-15% and belongs to comparatively low-risk, and the rhythm of the heart is continued above and belongs to high risk normal range 15%, needs carry out senior monitoring at once or go to nearby hospitals to seek medical advice.Also such as: the 4Hz-6Hz frequency content normalized energy of setting surface electromyogram signal is less than 30%, and surface electromyogram signal continuous exhibition without or slightly to tremble or stiff for devoid of risk; The 4Hz-6Hz frequency content normalized energy of surface electromyogram signal is greater than 30% and is less than 60%, and surface electromyogram signal continuous exhibition moderate tremble or stiff be comparatively low-risk; The 4Hz-6Hz frequency content normalized energy of surface electromyogram signal is greater than 60%, and surface electromyogram signal continuous exhibition severe is trembled or stiff for high risk.

Further, in described step S15, if described signal acquisition module 240 cannot collect the electricity physiological signal of patient by described electricity physiological signal sensor 300, then described microprocessor 250 sends report, so that doctor processes in time to described remote monitoring server 600.

In described step S16, described microprocessor 250 obtains check code by described third communication module 230 to described remote monitoring server 600, thus judges that whether this long-range program control command is legal.

In described step S17, send instruction by described first communication module 210 to described implantable medical devices 100.

In described step S18, this program control result is sent to described remote monitoring server 600 further comprising the steps:

Step S181, is simply analyzed program control result by described microprocessor 250, classifies according to different risk class;

Step S182, when risk class is lower, is sent to described patient customer by described second communication module 220 by program control result and holds 400, then holds 400 to be sent to described remote monitoring server 600 through described patient customer; And

Step S183, when risk class is higher, is directly sent to described remote monitoring server 600 by program control result, so that doctor processes in time by described third communication module 230.Such as this implantable medical devices 100 running voltage is greater than 2.9V is devoid of risk, be less than 2.9V and be greater than 2.7V for there being comparatively low-risk, being less than 2.7V for there being high risk, needing contact the work that stops this implantable medical devices 100 immediately with mster-control centre or change battery.

In described step S19, indicate communication failure by described display screen 260.

Further, the method for work of long distance control system 10 of the present utility model is further comprising the steps of:

Step S20, the electricity physiological signal received is transferred to described data analytics server 700 by described remote monitoring server 600;

Step S21, described data analytics server 700 carries out analyzing and processing to this electricity physiological signal and by the result feedback that carries out after analyzing and processing to described remote monitoring server 600; And

Step S22, this result is sent to described doctor terminal 500 by described remote monitoring server 600, and presents to doctor by this doctor terminal 500.

In described step S21, the analytical method of described data analytics server 700 to this electricity physiological signal comprises analytical methods such as utilizing linear analysis, nonlinear analysis and machine learning.

For the surface electromyogram signal of disturbances in patients with Parkinson disease, by described data analytics server 700, the method that the surface myoelectric data collected carry out on-line operation process is comprised the following steps:

Step S211, carries out noise eliminating filter to this surface electromyogram signal;

Step S212, is normalized this surface electromyogram signal, and its normalization formula followed is:

S E M G = \frac{x_{i} - \frac{m a x (x) + m i n (x)}{2}}{\frac{\max (x) - m i n (x)}{2}}

Wherein, x is initial surface myoelectricity data, x _ifor each collection point of initial data, SEMG is the surface myoelectric data after normalization.The SEMG signal obtained after process is for carrying out depth calculation; And

Step S213, calculate integral status scoring, its formula followed is:

U＝ω ₁·RMS+ω ₂·MDF+ω ₃·Kur+ω ₄·Samp+ω ₅·Efreq+ω ₆REC

Wherein, RMS is the normalization virtual value of surface electromyogram signal, and computational methods are:

R M S = \sqrt{\frac{1}{n} Σ_{i = 1}^{n} {SEMG}^{2}};

MDF is the intermediate frequency of surface electromyogram signal, after adopting the method for numerical computations to calculate the power Spectral Estimation of signal, finds the frequency by power spectrum area is divided into two to be intermediate frequency;

Kur is coefficient of kurtosis, and its computing formula is:

K u r = \frac{Σ_{i = 1}^{n} {({SEMG}_{i} - \overset{&OverBar;}{S} \overset{&OverBar;}{E} \overset{&OverBar;}{M} \overset{&OverBar;}{G})}^{4}}{{nδ}^{4}}

Samp is Sample Entropy;

Efreq is the gross energy of disturbances in patients with Parkinson disease myoelectricity 3Hz-10Hz frequency content, and computing formula is:

E f r e q = {&Integral;}_{3}^{10} P (f) d f;

REC is the data regression rate index in recurrence quantification analysis;

ω ₁~ ω ₆for the weight sequence of every patient, it can utilize linear analysis, nonlinear analysis, machine learning scheduling algorithm to carry out contrast learning to the history case history of patient and history surface myoelectric data and obtain by described data analytics server 700.Under this weight, the comprehensive parkinson of giving a mark in U and patient medical record that described data analytics server 700 calculates are unified scale (UPDRS) mark and are had maximum correlation coefficient.Sequence is chosen according to the IP of patient stored in described data analytics server 700, for calculating online later through what optimize.

In the present embodiment, utilize above-mentioned data analytics server 700, weight analysis and index calculate are carried out to 7 examples frank disturbances in patients with Parkinson disease of trembling, analysis result shows, under the final weight selected, the significance of U value computation model can reach 0.96 (p<0.1), can as effective online evaluation means.Be appreciated that, the indices that this utility model utilizes various analytical method (time-domain analysis, frequency-domain analysis, nonlinear analysis etc.) to calculate, the score value of unifying scale by the method for weighted calculation and parkinson carries out relevant, to doctor, there is significant reference significance, patient behavior symptom can be showed by the analysis of electricity physiological signal.

In described step S22, the analysis result of this electricity physiological signal is presented on the audio frequency and video assembly 550 of described doctor terminal 500 by described remote monitoring server 600 in the form of a web page.Particularly, described result is presented in the senior monitoring module 617 of described remote monitoring website.Doctor can judge whether will carry out parameter adjustment or closing process etc. to the implantable medical devices 100 in patient body according to the analysis result of this electricity physiological signal.

Further, in described step S22, the analysis result of this electricity physiological signal is kept at described monitoring parameter to described remote monitoring server 600 and patient's states is inquired about/preserved in module 6175.The analysis result of described data analytics server 700 and described monitoring parameter and patient's states are inquired about/are preserved the analysis result stored in module 6175 and compare by described remote monitoring server 600, and compare of analysis result is presented to doctor.

Be appreciated that, in described step S22, this result also can not be sent to described doctor terminal 500 by described remote monitoring server 600, but the Common Parameters in the patient medical record information stored automatically is selected according to the analysis result of described data analytics server 700, send to this implantable medical devices 100 and carry out parameter adjustment or out code.

Refer to Figure 11, this utility model second embodiment provides a kind of long distance control system 20 of implantable medical devices 100, and it comprises: implantable medical devices 100, patient body outer controller 200, electricity physiological signal sensor 300, signal acquisition controller 900, patient customer holds 400, one doctor terminal 500, remote monitoring server 600, data analytics server 700 and an Audio Visual Communication server 800.Wherein, described patient body outer controller 200, described electricity physiological signal sensor 300 He, described patient customer holds 400 jointly to form a patient terminal.

The structure of the long distance control system 10 of the implantable medical devices 100 that the long distance control system 20 of the implantable medical devices 100 that this utility model second embodiment provides provides with this utility model first embodiment is substantially identical, its difference is, described long distance control system 20 comprises a signal acquisition controller 900 further, described electricity physiological signal sensor 300 is connected with described signal acquisition controller 900, and be not connected with this patient body outer controller 200, and by this signal acquisition controller 900 hold with described patient customer respectively 400 and described remote monitoring server 600 be connected.That is, in this utility model first embodiment, described signal acquisition controller 900 is integrated with described patient body outer controller 200.

Be appreciated that in this utility model second embodiment, described patient body outer controller 200 inside is without the need to signalization acquisition module 240.Because described electricity physiological signal sensor 300 is without the need to being connected to this patient body outer controller 200, therefore patient is being monitored remotely in process, only needs this signal acquisition controller 900 to carry with, and does not need to carry with this patient body outer controller 200.

Particularly, refer to Figure 12, this signal acquisition controller 900 comprises first communication module 910, second communication module 920, microprocessor 930 and a signal acquisition module 940.Described first communication module 910 for holding 400 communications with described patient customer, described second communication module 920 for the communication of described remote monitoring server 600.Described microprocessor 930 is selected by this signal acquisition module 940 and controls this electricity physiological signal sensor 300 to gather different physiological signals.Described signal acquisition module 940 is identical with described signal acquisition module 240 structure.

Further, described signal acquisition controller 900 also comprises an electricity physiological signal discrimination module 950.Described microprocessor 930 is connected with this electricity physiological signal discrimination module 950.Preferably, described electricity physiological signal discrimination module 950 is connected between described microprocessor 930 and this signal acquisition module 940.Described electricity physiological signal discrimination module 950 is identical with described electricity physiological signal discrimination module 290 structure.

The method of work of described long distance control system 20 is substantially identical with the method for work of above-mentioned long distance control system 10, its difference is, controls this electricity physiological signal sensor 300 gather the electricity physiological signal of patient and send this electricity physiological signal by described signal acquisition controller 900.

The long distance control system of the implantable medical devices that this utility model provides has the following advantages.The first, gathered the electricity physiological signal of patient by described electricity physiological signal sensor 300, monitoring means variation, can realize the monitoring more comprehensively to patient.The second, by described data analytics server 700 for carrying out on-line analysis to the electric physiological data of patient, and analysis result being presented to doctor, making the monitoring of patient safer and more effective.

In addition, those skilled in the art can also do other changes in this utility model spirit, and these changes done according to this utility model spirit all should be included in this utility model scope required for protection.

Claims

1. a patient terminal for the long distance control system of implantable medical devices, it comprises:

One patient customer's end; And

One patient body outer controller, described patient body outer controller is held with described patient customer and is connected;

It is characterized in that, comprise an electricity physiological signal sensor and a signal acquisition controller further; Described electricity physiological signal sensor is for gathering the electricity physiological signal of patient, and this electricity physiological signal is sent to described patient customer end by described signal acquisition controller.

2. the patient terminal of the long distance control system of implantable medical devices as claimed in claim 1, it is characterized in that, described signal acquisition controller comprises: one for the first communication module of described patient customer's end communication, one for the second communication module of a remote monitoring server communication, a microprocessor and a signal acquisition module; Described microprocessor to be connected from this electricity physiological signal sensor by this signal acquisition module and for selecting and controlling the different physiological signal of this electricity physiological signal sensor acquisition.

3. the patient terminal of the long distance control system of implantable medical devices as claimed in claim 1, it is characterized in that, described signal acquisition controller and described patient body outer controller integrated, described patient body outer controller comprises: one for the first communication module of described implantable medical devices communication, one for the second communication module of described patient customer's end communication, one for the third communication module of a remote monitoring server communication, a signal acquisition module, a microprocessor, a display screen, a button and switch and a power management module; Described microprocessor to be connected from this electricity physiological signal sensor by this signal acquisition module and for selecting and controlling the different physiological signal of this electricity physiological signal sensor acquisition.

4. the patient terminal of the long distance control system of implantable medical devices as claimed in claim 2 or claim 3, it is characterized in that, described signal acquisition controller also comprises an electricity physiological signal discrimination module be connected with described microprocessor, described electricity physiological signal discrimination module is used for analyzing the electricity physiological signal that this signal acquisition module collects, and classifies according to different risk class.

5. the patient terminal of the long distance control system of implantable medical devices as claimed in claim 4, it is characterized in that, described electricity physiological signal discrimination module is connected between described microprocessor and this signal acquisition module.

6. the patient terminal of the long distance control system of implantable medical devices as claimed in claim 2 or claim 3, it is characterized in that, described signal acquisition module comprises a signal input interface, a signal conditioning circuit be connected with this signal input interface and a signal output interface be connected with this signal conditioning circuit; Described signal conditioning circuit is exported by described signal output interface after being used for carrying out stress release treatment and processing and amplifying to the signal collected.

7. the patient terminal of the long distance control system of implantable medical devices as claimed in claim 6, it is characterized in that, described signal input interface comprises: the selector module that a wired interface module, a radio interface module and are connected with described wired interface module and radio interface module respectively; Described selector module is controlled by described microprocessor, selects data channel, thus realizes the collection to unlike signal.

8. the patient terminal of the long distance control system of implantable medical devices as claimed in claim 6, it is characterized in that, described signal output interface comprises: an analog to digital conversion circuit and a digital output port be connected with this analog to digital conversion circuit; Described digital output port is connected with described MPI.

9. the patient terminal of the long distance control system of implantable medical devices as claimed in claim 1, it is characterized in that, described electricity physiological signal sensor is one or more in surface myoelectric electrode, electrocardioelectrode, implanted brain depth electrode, acceleration transducer and electrocardio Holter.

10. the patient terminal of the long distance control system of implantable medical devices as claimed in claim 9, is characterized in that, described surface myoelectric electrode, electrocardioelectrode and described signal acquisition controller wired connection; Described implanted brain depth electrode, electrocardio Holter and described signal acquisition controller wireless connections.