CN204798414U - Liquid device is joined in marriage in sterilization - Google Patents

Liquid device is joined in marriage in sterilization Download PDF

Info

Publication number
CN204798414U
CN204798414U CN201520377554.3U CN201520377554U CN204798414U CN 204798414 U CN204798414 U CN 204798414U CN 201520377554 U CN201520377554 U CN 201520377554U CN 204798414 U CN204798414 U CN 204798414U
Authority
CN
China
Prior art keywords
agitation tank
marriage
diaphragm valve
pneumatic diaphragm
fluid reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201520377554.3U
Other languages
Chinese (zh)
Inventor
吴海华
薛元
连海洲
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHANGHAI PNC PROCESS SYSTEMS CO Ltd
Original Assignee
SHANGHAI PNC PROCESS SYSTEMS CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHANGHAI PNC PROCESS SYSTEMS CO Ltd filed Critical SHANGHAI PNC PROCESS SYSTEMS CO Ltd
Priority to CN201520377554.3U priority Critical patent/CN204798414U/en
Application granted granted Critical
Publication of CN204798414U publication Critical patent/CN204798414U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

The utility model discloses a liquid device is joined in marriage in sterilization, be used for controlling pure steam get into the first pneumatic diaphragm valve of joining in marriage the fluid reservoir on pure delivery duct say including joining in marriage the fluid reservoir, saying and set up with the pure delivery duct that joins in marriage fluid reservoir intercommunication, still include the vacuum pump, be used for to connect the vacuum pump and join in marriage the fluid reservoir the vacuum tube way, set up the pneumatic diaphragm valve of second that is used for opening or close the evacuation action of joining in marriage the fluid reservoir on vacuum tube says and be used for detecting the pressure sensor of the pressure value in joining in marriage the fluid reservoir. The utility model provides a liquid device is joined in marriage in sterilization can effectually get rid of join in marriage the cold air in the fluid reservoir for pure steam can cover completely on joining in marriage the jar wall of fluid reservoir, eliminate sterilization " dead angle ".

Description

A kind of sterilizing liquid dispensing device
Technical field
This utility model relates to field of biological pharmacy, particularly relates to a kind of sterilizing liquid dispensing device.
Background technology
In the production of bio-pharmaceuticals industry, especially in drug solution preparing system (abbreviation liquid mixing system), the various storage tanks such as material-compound tank can be used, and each storage tank needs CIP (on-line cleaning) and SIP (online sterilizing), wherein, SIP utilizes saturated vapor effectively to kill microorganism and brood gemma within a short period of time, ensures the sterility requirements of system.
SIP can meet the washing and sterilizing etc. of material storing storage tank and transfer pipeline, is mainly used in the systems such as infusion solutions, sterile preparation, freeze-dried powder, vaccine.
In prior art, as shown in Figure 1, sterilizing liquid dispensing device comprises Agitation Tank 1, first pneumatic diaphragm valve 3 and pure steam conveying pipe 2, Agitation Tank 1 is for completing the preparation of medicinal liquid, when needs carry out sterilization treatment to Agitation Tank 1, general employing directly passes into the method for pure steam in Agitation Tank 1 by pure steam conveying pipe 2, carry out high temperature sterilize to Agitation Tank 1 and the pipe-line system that is connected.
In prior art, owing to directly passing into the complete emptying of cold air that pure steam cannot ensure in Agitation Tank 1, cause forming sterilizing " dead angle " and bag point in Agitation Tank 1, cause sterilizing not thorough, do not reach the object of effective sterilizing, there is the halfway hidden danger of sterilizing and material risk.
Therefore, how effectively getting rid of the cold air in Agitation Tank, is the current technical issues that need to address of those skilled in the art.
Utility model content
The purpose of this utility model is to provide a kind of sterilizing liquid dispensing device, for getting rid of the cold air in Agitation Tank.
For solving the problems of the technologies described above, this utility model provides following technical scheme:
A kind of sterilizing liquid dispensing device, comprises Agitation Tank, the pure steam conveying pipe be communicated with described Agitation Tank and is arranged on the first pneumatic diaphragm valve described pure steam conveying pipe entering described Agitation Tank for controlling pure steam, also comprising:
Vacuum pump;
For connecting the vacuum lead of described vacuum pump and described Agitation Tank;
Be arranged on described vacuum lead for opening or close the second pneumatic diaphragm valve of the evacuation action of described Agitation Tank;
For detecting the pressure transducer of the force value in described Agitation Tank.
Preferably, above-mentioned sterilizing liquid dispensing device also comprises for judging force value in described Agitation Tank whether lower than the judgment means of preset pressure value.
Preferably, described judgment means is also for sending to described first pneumatic diaphragm valve and described second pneumatic diaphragm valve by judged result, described first pneumatic diaphragm valve and described second pneumatic diaphragm valve are opened according to described judged result or closed.
Preferably, described pressure transducer is arranged on the outer surface of described Agitation Tank.
Preferably, the bottom of described Agitation Tank is also provided with the magnetic stirring apparatus for stirring medicinal liquid.
Preferably, the bottom of described Agitation Tank is also provided with the bottom valve flowing into other tank bodies for controlling medicinal liquid.
Sterilizing liquid dispensing device provided by the utility model, adds vacuum pump, vacuum lead, the second pneumatic diaphragm valve and the pressure transducer for detecting the force value in Agitation Tank compared to prior art.This device utilizes vacuum pump to be extracted out by the cold air in described Agitation Tank, after the force value in described Agitation Tank is lower than preset pressure value, namely after reaching certain vacuum in described Agitation Tank, in described Agitation Tank, pass into pure steam, effectively can be got rid of the cold air in described Agitation Tank by the method for evacuation.In addition, in order to get rid of the cold air in described Agitation Tank more thoroughly, can to after passing into pure steam in described Agitation Tank, and then to after described Agitation Tank evacuation, then in described Agitation Tank, second pure steam is passed into, 99.99% cold air can found time after evacuation in described Agitation Tank in triplicate.This device effectively can get rid of the cold air in described Agitation Tank, and pure steam can be covered on the tank skin of described Agitation Tank completely, eliminates sterilizing " dead angle " and bag point.
Accompanying drawing explanation
Fig. 1 is the structural representation of sterilizing liquid dispensing device in prior art;
Fig. 2 is the structural representation of a kind of detailed description of the invention of sterilizing liquid dispensing device provided by the utility model.
Detailed description of the invention
Core of the present utility model is to provide a kind of sterilizing liquid dispensing device, effectively can get rid of the cold air in Agitation Tank before sterilization.
In order to make those skilled in the art person understand this utility model scheme better, below in conjunction with the drawings and specific embodiments, the utility model is described in further detail.
Please refer to Fig. 2, Fig. 2 is the structural representation of a kind of detailed description of the invention of sterilizing liquid dispensing device provided by the utility model.
In this embodiment, sterilizing liquid dispensing device comprises Agitation Tank 1, the pure steam conveying pipe 2 be communicated with Agitation Tank 1 and is arranged on the first pneumatic diaphragm valve 3 pure steam conveying pipe 2 entering Agitation Tank 1 for controlling pure steam, also comprise vacuum pump 4, for connect vacuum pump 4 and Agitation Tank 1 vacuum lead 5, be arranged on vacuum lead 5 for opening or close the second pneumatic diaphragm valve 6 of the evacuation action of Agitation Tank 1 and the pressure transducer 7 for detecting the force value in Agitation Tank 1.
When needs carry out sterilization treatment to Agitation Tank 1, first vacuum pump 4 is opened, then the second pneumatic diaphragm valve 6 is opened, vacuum pump 4 carries out evacuation by vacuum lead 5 pairs of Agitation Tanks 1, then pressure transducer 7 is utilized to detect force value in Agitation Tank 1, and judge that whether force value in Agitation Tank 1 is lower than preset pressure value, if, then close the second pneumatic diaphragm valve 6, open the first pneumatic diaphragm valve 3, in Agitation Tank 1, pass into pure steam, if not, then continue to carry out evacuation to Agitation Tank 1.Pass into pure steam again to after Agitation Tank 1 evacuation, effectively can reduce the residual quantity of the cold air in Agitation Tank 1.
In order to get rid of the cold air in Agitation Tank 1 more thoroughly, after pure steam can being passed into Agitation Tank 1, evacuation again, again pass into pure steam, for diluting the cold air in Agitation Tank 1, the process of evacuation can in triplicate, 99.99% cold air can found time after three evacuation in Agitation Tank 1, and the technology that repetition evacuation carries out sterilizing belongs to vacuum impulse sterilization technology.Here it should be noted that, three evacuation are enough to meet sterilizing demand, and more evacuation can cause waste.
This sterilizing liquid dispensing device is connected to the vacuum pipe network in factory in Agitation Tank 1, adds vacuum pump 4, vacuum lead 5, second pneumatic diaphragm valve 6 and the pressure transducer 7 for detecting the force value in Agitation Tank 1 compared to prior art.This device utilizes vacuum pump 4 to be extracted out by the cold air in Agitation Tank 1, after the force value in Agitation Tank 1 is lower than preset pressure value, namely after reaching certain vacuum in Agitation Tank 1, pure steam is passed in Agitation Tank 1, and then to after Agitation Tank 1 evacuation, again in Agitation Tank 1, pass into pure steam.This device effectively can get rid of the cold air in Agitation Tank 1, and pure steam can be covered on the tank skin of Agitation Tank 1 completely, eliminates sterilizing " dead angle ", meanwhile, in the pipeline be communicated with Agitation Tank 1, serves the effect of sterilizing equally.
Concrete, after the force value that pressure transducer 7 detects in Agitation Tank 1, can be artificial judge that whether force value in Agitation Tank 1 is lower than preset pressure value, and by setting up judgment means, artificial control first pneumatic diaphragm valve 3 and the unlatching of the second pneumatic diaphragm valve 6 or closedown, also can judge that whether force value in Agitation Tank 1 is lower than preset pressure value.In addition, judgment means is also for sending to the first pneumatic diaphragm valve 3 and the second pneumatic diaphragm valve 6, first pneumatic diaphragm valve 3 and the second pneumatic diaphragm valve 6 to open or closedown according to judged result by judged result.By setting up judgment means, without the need to artificially judging that the force value in Agitation Tank 1 reaches preset pressure value, automation mechanized operation can be realized.
On the other hand, for the ease of the installation of pressure transducer 7 and the reading of data, pressure transducer 7 can be arranged on the outer surface of Agitation Tank 1.The number of pressure transducer 7 can be one, can be multiple, draw the actual pressure value in Agitation Tank 1, making testing result more accurate by averaging.
Except above-mentioned setting, the bottom of Agitation Tank 1 is also provided with the magnetic stirring apparatus 8 for stirring medicinal liquid.After Agitation Tank 1 sterilizing, in Agitation Tank 1, add medicinal liquid, magnetic stirring apparatus 8 can accelerate the mixing speed of medicinal liquid, makes the stirring of medicinal liquid more even.In addition, after the medicinal liquid in Agitation Tank 1 machines, need the tank body proceeding to other, therefore the bottom of Agitation Tank 1 is also provided with the bottom valve 9 flowing into other tank bodies for controlling medicinal liquid.Open bottom valve 9, medicinal liquid just can flow out in Agitation Tank 1, after hygiene-type centrifugal pump and sterilizing filter, enters receiving tank and stores.Here it should be noted that, for other tank bodies in medicinal liquid system and pipeline, vacuum impulse sterilization technology can be adopted equally to carry out sterilizing.
Above sterilizing liquid dispensing device provided by the utility model is described in detail.Apply specific case herein to set forth principle of the present utility model and embodiment, the explanation of above embodiment just understands method of the present utility model and core concept thereof for helping.Should be understood that; for those skilled in the art; under the prerequisite not departing from this utility model principle, can also carry out some improvement and modification to this utility model, these improve and modify and also fall in the protection domain of this utility model claim.

Claims (6)

1. a sterilizing liquid dispensing device, comprise Agitation Tank (1), the pure steam conveying pipe (2) be communicated with described Agitation Tank (1) and be arranged on the first pneumatic diaphragm valve (3) described pure steam conveying pipe (2) entering described Agitation Tank (1) for controlling pure steam, it is characterized in that, also comprise:
Vacuum pump (4);
For connecting the vacuum lead (5) of described vacuum pump (4) and described Agitation Tank (1);
Be arranged on described vacuum lead (5) for opening or close second pneumatic diaphragm valve (6) of the evacuation action of described Agitation Tank (1);
For detecting the pressure transducer (7) of the force value in described Agitation Tank (1).
2. sterilizing liquid dispensing device according to claim 1, is characterized in that, also comprises for judging force value in described Agitation Tank (1) whether lower than the judgment means of preset pressure value.
3. sterilizing liquid dispensing device according to claim 2, it is characterized in that, described judgment means is also for sending to described first pneumatic diaphragm valve (3) and described second pneumatic diaphragm valve (6) by judged result, described first pneumatic diaphragm valve (3) and described second pneumatic diaphragm valve (6) are opened according to described judged result or closed.
4. the sterilizing liquid dispensing device according to claims 1 to 3 any one, is characterized in that, described pressure transducer (7) is arranged on the outer surface of described Agitation Tank (1).
5. sterilizing liquid dispensing device according to claim 4, is characterized in that, the bottom of described Agitation Tank (1) is also provided with the magnetic stirring apparatus (8) for stirring medicinal liquid.
6. sterilizing liquid dispensing device according to claim 5, is characterized in that, the bottom of described Agitation Tank (1) is also provided with the bottom valve (9) flowing into other tank bodies for controlling medicinal liquid.
CN201520377554.3U 2015-06-03 2015-06-03 Liquid device is joined in marriage in sterilization Active CN204798414U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201520377554.3U CN204798414U (en) 2015-06-03 2015-06-03 Liquid device is joined in marriage in sterilization

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201520377554.3U CN204798414U (en) 2015-06-03 2015-06-03 Liquid device is joined in marriage in sterilization

Publications (1)

Publication Number Publication Date
CN204798414U true CN204798414U (en) 2015-11-25

Family

ID=54583315

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201520377554.3U Active CN204798414U (en) 2015-06-03 2015-06-03 Liquid device is joined in marriage in sterilization

Country Status (1)

Country Link
CN (1) CN204798414U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104922705A (en) * 2015-06-03 2015-09-23 上海至纯洁净系统科技股份有限公司 Sterilization liquid-preparation device and sterilization method
CN105536011A (en) * 2016-03-14 2016-05-04 上海东富龙拓溥科技有限公司 Liquid mixing system and full-automatic online sterilization control method based on same

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104922705A (en) * 2015-06-03 2015-09-23 上海至纯洁净系统科技股份有限公司 Sterilization liquid-preparation device and sterilization method
CN105536011A (en) * 2016-03-14 2016-05-04 上海东富龙拓溥科技有限公司 Liquid mixing system and full-automatic online sterilization control method based on same
CN105536011B (en) * 2016-03-14 2017-12-08 上海东富龙拓溥科技有限公司 Liquid mixing system and its full-automatic online sterilizing control method

Similar Documents

Publication Publication Date Title
CN204816450U (en) Automatic constant voltage charge device
CN204798414U (en) Liquid device is joined in marriage in sterilization
CN107051251A (en) A kind of complete liquid mixing system of liquid drugs injection
CN203625355U (en) Aseptic liquid blending and supplying system
CN103752555A (en) CIP-SIP (cleaning in place-sterilizing in place) system for bottle cleaning machine
CN103382440A (en) Safe inoculation device of liquid fermentation tank
CN104922705A (en) Sterilization liquid-preparation device and sterilization method
CN206014870U (en) A kind of microorganism fermentation tank feed supplementing device
CN208395171U (en) A kind of biopharmaceutical liquids material transmitting isolating and protecting device
CN206868040U (en) A kind of complete liquid mixing system of liquid drugs injection
CN202699659U (en) On-line sterilization device used for lyophilizer
CN210065134U (en) Aseptic filling equipment is used in fruit vegetables juice production
CN108144373B (en) Sterile transfer system for sterile ophthalmic ointment materials
CN205633260U (en) Bottling machine
CN208492805U (en) Central liquid supply system
CN207748906U (en) Purified water and its pipeline sterilization system
CN207169781U (en) A kind of contactless water bath device
CN206950372U (en) A kind of full-automatic chemical sterilizes reverse osmosis water lines processing system
CN206896531U (en) A kind of disinfection system of liquid dispensing device
CN203711397U (en) On-line cleaning and drying integrated system for high-activity product equipment
CN205223259U (en) Cell culture base fermentation cylinder of sterilizing evenly
CN208814997U (en) A kind of asepsis feeding device
CN209039470U (en) Sterile material storage and transfer device
CN203741336U (en) Biological safety type zymophyte liquid hollow fiber ultrafiltration system
CN109837209A (en) Guarantee that concentrate is sterile and the automatic inactivation system of inactivating efficacy in production of vaccine

Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CP02 Change in the address of a patent holder
CP02 Change in the address of a patent holder

Address after: No. 170 purple sea road, Minhang District, Shanghai

Patentee after: Shanghai PNC Process Systems Co., Ltd.

Address before: 200241 03A 1, Ting 1 building, 555 Dongchuan Road, Minhang District, Shanghai.

Patentee before: Shanghai PNC Process Systems Co., Ltd.