CN204666397U - A kind of saliva three link detection reagent kit - Google Patents
A kind of saliva three link detection reagent kit Download PDFInfo
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- CN204666397U CN204666397U CN201520316900.7U CN201520316900U CN204666397U CN 204666397 U CN204666397 U CN 204666397U CN 201520316900 U CN201520316900 U CN 201520316900U CN 204666397 U CN204666397 U CN 204666397U
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Abstract
The utility model provides a kind of saliva three link detection reagent kit, and it comprises saliva collection bar, and saliva collection bar comprises handheld terminal, the spongy top can collecting saliva sample and coupling part, two ends; Detect cup, it comprise containing three joint inspections survey clamps sidewall sections, can containing receiving the collecting chamber of saliva collection bar and upper cover part; Base, it comprises ramped shaped groove, pad and plastic bottom board, and plastic bottom board is welded and fixed with detection cup edge.The utility model provides a kind of detection kit saliva collection and saliva being detected integration, provide a kind of dry chemical scrip controls sampling quantity application to sampling process simultaneously, avoid sampling quantity in conventional saliva collection process to hold inaccurate, resample the time and the wasting of resources of causing.Be applicable to the preliminary screening suspicious drug abuse colony being carried out to on-the-spot fast qualitative, for the abuse of control, Treatment monitoring m orphine, amphetamine, chloramines ketone contributes.
Description
Technical field
The utility model relates to a kind of saliva three link detection reagent kit.
Background technology
Morphine is topmost alkaloid in opium (being commonly called as opium), and morphine has analgesia and syngignoscism, is used clinically as narcotic analgeiscs, and the most frequently used medication of morphine is injection, oral also effective.Its maximum shortcoming is easy habituation, is thus abused.Heroin is the diacetylated derivatives of morphine; its water-soluble larger than morphine; absorb also faster; and it is fat-soluble also larger; easily enter maincenter by blood-brain barrier and play its effect; thus itself is additive stronger, and bad spinoff and the hazard analysis and HACCP that causes individual and society are considerably beyond its medical value.Opioid drug can make human body produce floaty euphoria, illusion sense.Once stop exogenous opioid medicine to enter human body, ten Iarge-scale system functions get muddled very soon, just there will be uneasiness, anxiety, sometimes hot and sometimes cold, cover with gooseflesh, shed tears, runny nose, perspiration, Nausea and vomiting, stomachache, diarrhoea, even whole body is twitched, embrace butt wall etc., be habituation outbreak symptom.
Meth is the one in amphetamines.Drug-pedlars are made into hydrochloride (i.e. hydrochloride methyl amphetamine), and this is the crystal of a kind of outward appearance like the irregular white of ice, namely domestic usually said ice.The abuse approach of meth has the modes such as smoking-collecting type, injecting type, swallowing type and nose suction-type, has accounted for great majority at present with intravenous injection and oral way.Meth can produce excitation and glad effect to central nervous system, make people feel incomparable glad of spirit and QI cleaning, heart and vigorously pleased, self-confidence and self-consciousness greatly strengthen, full of vitality, all fatigue is cleared off immediately, visual cognitive ability, work efficiency and ability to work improve rapidly, energy exception abundant, what and then occur is then fatigue, taediumvitae and the One's spirits are drooping symptom such as depressed of making us disliking very much and feeling bad very much.
Ketamine is commonly called as KET, is a kind of non-barbiturates anesthetic, can provide quick, the degree of depth, dissociation anesthesia.Ketamine takes in mode has cigarette to inhale clothes, snuffing, intravenous injection or oral (comprise dissolve in beverage and wine drink etc.) by powder etc.Ketamine also can stimulate cardiovascular system, and blood pressure, cardiac index, heart rate and pulmonary arterial pressure are all raised.After using ketamine, certain mental symptom can be produced, show as multiple multi-form illusion: the bigoted thinking slowly formed, the enhancing of sexual drive, the susceptibility enhancing etc. of sense organ, and these symptoms are dose dependent.
Opiates, amphetamine and chloramines ketone abuse in the market the most extensively, endanger maximum dependence producing drug.Therefore, set up a kind of accurate, quick, sensitive, easy, opiates, amphetamine and ketamine can be detected again simultaneously and detect the abuse important in inhibiting of reagent to prevention, control, Treatment monitoring illegal harvesting.
The domestic and international analysis and research to drug abuse in early days adopt the traditional biological samples such as blood, urine, hair more.Wherein, urine detection is that police law execution department carries out the conventional means of preliminary examination to suspicious crowd, if urine detection result is positive, then needs to turn and does further blood and quantitatively detect, to clarify a diagnosis.Although urine detection is comparatively extensive as preliminary examination application, because urine detection sampling process relates to privacy, cannot carry out face to face, sample is easily played tricks; And passway of metabolism is long, the interference of other metabolism in easy acceptor.
In view of above-mentioned urine specimen, to there is influence factor more and have the risk of playing tricks, and therefore needs a kind of better method to carry out the collection of sample.Abroad in Recent Years is devoted to research saliva sample as new sample, development of new saliva detection kit, but the product that home market is detected for saliva remains unchanged very single, a lot of manufacturer is separated saliva collector with detection clamp, be added drop-wise on clamp after collecting saliva with saliva collector and detect, sampling amount can not get controlling accurately and also have certain pollution risk in the process of sample transfer, therefore need develop a kind of joint-detection that saliva collection and the detection kit detecting integration can be used for one or more drug abuse.
Summary of the invention
Technical problem to be solved in the utility model is to provide a kind of saliva three link detection reagent kit saliva collection and saliva being detected integration.For this reason, the utility model is by the following technical solutions: it comprises saliva collection bar, connect under the annulus contiguous block that this saliva collection bar connects under comprising handheld terminal, the seal of fixing handheld terminal, seal, annulus contiguous block external diameter down diminish gradually loop connecting block, the plastics connecting link connected under loop connecting block, the plastics connecting link other end the sponge end of the saliva sample collected;
Detect cup, this detection cup comprise containing three joint inspections survey clamps sidewall, can containing receiving the collecting chamber of saliva collection bar and upper cover;
Base, comprises ramped shaped groove, pad and plastic bottom board, and plastic bottom board is welded and fixed with detection cup edge.
On the basis adopting above technical scheme, the utility model can also adopt following further scheme:
Be provided with two activity bit in described collecting chamber, one is the first activity bit under sponge end state of nature, and described collecting chamber upper end arranges trapezoidal bayonet socket and salient point, and described first activity bit is pinned by trapezoidal bayonet socket and bump; One is the second activity bit after sponge end is extruded, and now inner chamber upper end open and plane section cone fit like a glove and make it to seal.
Described plastics connecting link internal fixtion has dry chemistry reagent bar, and when saliva amount is enough, reagent strip can show redness, and prompting saliva collection process terminates.
Described collecting chamber is cylindrical cavity, collecting chamber lower end is semiclosed, semi-circular opening passes through the ramped shaped groove associating of plastics partition and base, form airtight passage for salivary flow, put into collecting chamber after saliva collection bar sponge end is moistening by saliva of buccal cavity to compress through sidewall and bottom, saliva flows into base groove by semi-circular opening, is reacted by pad and test strip.
Detect clamp containing saliva in the sidewall of described detection cup, be provided with three draw-in grooves in clamp, be equipped with morphine, meth, ketamine test strip in draw-in groove respectively, expose bottom test strips outside clamp, with pad contacts.
Owing to have employed the technical solution of the utility model, saliva three link detection reagent kit can morphine, meth, ketamine in qualitative detection people saliva, easy and simple to handle, quick, does not limit by when and where, do not need any instrument and equipment, result can intuitive judgment, cheap, is applicable to process batch sample, compared with detecting with common saliva, achieve the integration of saliva collection and detection, sampling amount obtains accurate control, avoids the waste that sampling amount is forbidden to cause kit.Be applicable to the preliminary screening suspicious drug abuse colony being carried out to on-the-spot fast qualitative, for the abuse of control, Treatment monitoring m orphine, amphetamine, chloramines ketone contributes.
Accompanying drawing explanation
Fig. 1 is schematic perspective view of the present utility model;
Fig. 2 is the sectional view after the utility model STRUCTURE DECOMPOSITION;
Fig. 3 is STRUCTURE DECOMPOSITION figure of the present utility model;
Fig. 4 is for detecting three clamp schematic diagram in cup sidewall;
Embodiment
The utility model is described in further detail with embodiment below in conjunction with accompanying drawing 1, accompanying drawing 2, accompanying drawing 3, accompanying drawing 4.
The utility model relates to a kind of saliva three link detection reagent kit, and this kit comprises: saliva collection bar, and this saliva collection bar comprises handheld terminal, the spongy top collecting saliva sample and coupling part, two ends; Detect cup, this detection cup comprise containing three joint inspections survey clamps sidewall sections, can containing receiving the collecting chamber of saliva collection bar and upper cover part; Base, comprises ramped shaped groove, pad and plastic bottom board, and plastic bottom board is welded and fixed with detection cup edge.
Saliva collection bar is sample collection device, has two activity bit at collecting chamber inner chamber, and one is the activity bit under sponge end state of nature, is pinned by the trapezoidal bayonet socket of inner chamber upper end and bump; One is the activity bit after sponge end is extruded, and now inner chamber upper end open and plane section cone fit like a glove and make it to seal.
Holding with sponge the plastics connecting link internal fixtion dry chemistry reagent bar be connected, when saliva amount is enough, reagent strip can show redness, and prompting saliva collection process terminates.
Collecting chamber lower end is that semicircular closes semicircular opening, and semi-circular opening, by plastics partition and base groove associating, forms airtight passage for salivary flow.Put into collecting chamber after saliva collection bar sponge end is moistening by saliva of buccal cavity to compress through sidewall and bottom, saliva flows into base groove by semi-circular opening, is reacted by pad and test strip.
Detect in cup sidewall and detect clamp containing saliva, three draw-in grooves are provided with in clamp, morphine, meth, ketamine saliva test strip is equipped with respectively in draw-in groove, three test strips include holder, sample pad, colloidal gold pad and nitrocellulose filter, and holder is pasted with nitrocellulose filter, colloidal gold pad and sample pad successively.Be connected with pad bottom test strips, every root test strips is respectively equipped with pair of windows, is instructions window and view window respectively, and instructions window informs this root ELISA test strip thing of experimenter, and testing result observed by view window.View window is coated with nature controlling line C line and detection line T line, three test strips T lines is coated with respectively monoclonal antibodies against morphine, anti-meth monoclonal antibody and anti-ketamine monoclonal antibody, C line is all coated with sheep anti-mouse igg polyclonal antibody.
Embodiment
The utility model provides a kind of saliva three link detection reagent kit, comprises saliva collection bar 1, detects cup 2, base 3 and form.As shown in Figure 1.
Saliva collection bar 1 comprises handheld terminal 11, plastics connecting link 12, annulus contiguous block 13, sponge end 14, plane section cone 15 and seal 16.Plastics connecting link 12 is hollow circular cylinder, and lower end is connected with water-absorbing sponge 14 by annulus contiguous block 13, and whether inside is equipped with dry chemical scrip, saliva sampling amount can be pointed out sufficient, as sampling amount is sufficient, then shows redness.This embodiment can avoid sampling quantity in conventional saliva collection process to hold inaccurate, resamples the time and the wasting of resources of causing.As shown in Figure 3.
Detect cup 2 and comprise bowl cover 21, seal bore 22, sidewall 23, collecting chamber 24.Seal bore 22 containing receiving saliva collection shaft seal 16, can realize the sealing of whole kit.As shown in Figure 3.Collecting chamber 24 points of exocoels 51 and inner chamber 52 two parts, exocoel is cylindrical, inner chamber and saliva collection shaft seal match with lower part, inner chamber upper end open 53 is coincide with plane section cone size, side is seen in trapezoidal, same level place is provided with two outstanding soft spots as bayonet socket therein, the effect of bayonet socket be before using by saliva collection rod lock in state of nature, after handheld terminal force, saliva collection bar plane section cone lower edge breaks through bump, reach trapezoidal lower edge to fix, sponge end is in compressive state, and this is activity compression position.As shown in Figure 2.In collecting chamber, exocoel junction is closed, and intracavity bottom has semi-circular opening 25, by the plastics partition 26 of blind end lower end, with base groove associating, forms fluid passage.This embodiment achieves the integration that saliva sample is collected and detected.
Detect in cup sidewall 23 and three joint inspections survey clamps 4 are set, three clamps 4 are in inverted trapezoidal, three clamps 4 comprise draw-in groove 42 and test strips 41 is formed, test strips 41 is positioned at draw-in groove 42, expose only outside clamp and contact with pad 31, draw-in groove caves inward, and test strips is fixed in draw-in groove together with trough rim 43.The utility model clamp is three card-type, interior containing three draw-in grooves, be equipped with morphine saliva in draw-in groove respectively and detect reagent strip, meth saliva detection reagent strip, ketamine saliva detection reagent strip, three test strips are separate, cross reaction does not occur and causes interference.As shown in Figure 4.
Base 3 comprises pad 31, groove 32, base plate 33 form.Groove 32, in "T"-shaped, form by having recessed plastic dam 34, plastics partition 26 and detecting cup cup edge, forms the fluid passage of pattern detection.Be set to ramped shaped bottom the present embodiment further groove, make sample energy enough and arrive pad 31 place fast, accelerating reaction process.
In the saliva collection stage, pinch saliva collection bar handheld terminal 11 with hand, sponge end 14 is put into subject oral cavity (cheek portion, gum, tongue place), containing wiping sampling after a period of time.Represent that when the test strips in plastics connecting link reddens sampling quantity is enough, saliva collection bar can be taken out and transfer them in the collecting chamber of test cup.
Saliva detection-phase, saliva collection bar is put into collecting chamber, vertically exert a force to handheld terminal, the sponge end of collection bar is stressed to be compressed with sidewall and bottom squeeze, saliva flows into base from sponge end by semi-circular opening, flow to pad through ramped shaped groove, reacted by pad and three test strip.Sample is chromatography under capillary effect.As in sample containing morphine, meth, ketamine wherein one or more minimum detectabilities higher than test strips time, gold labeling antibody is all combined with measured matter, thus does not occur aubergine band at detection zone (T) because competitive reaction can not be combined with antigen-BSA bond; As in sample containing morphine, meth, ketamine wherein one or more minimum detectabilities lower than test strips time, gold labeling antibody can not all be combined with measured matter, unconjugated golden labeling antibody is combined with the antigen-BSA bond being fixed on detection line place in chromatography process, thus occurs an aubergine band at detection zone (T); No matter whether there is measured matter in saliva, all can there is an aubergine band in control zone (C).The aubergine band that control zone (C) presents judges whether enough sample sizes, and the whether normal standard of chromatography process, simultaneously also as the inner quality standard of reagent.
Whether the utility model belongs to immunology category, mainly through detecting containing morphine, meth, ketamine in suspicious crowd's saliva, thus judge whether to abuse opiates, amphetamine, chloramines ketone illegal harvesting.
Whether the utility model adopts containing morphine, meth, ketamine in colloidal gold immunochromatographimethod technology and the qualitative people's saliva of Competitive assays technology, thus judges whether to abuse opiates, amphetamine, chloramines ketone medicine.
In a word, the foregoing is only preferred embodiment of the present utility model, all equalizations done according to the utility model claim change and modify, and all should belong to the covering scope of the utility model patent.
Claims (5)
1. saliva three link detection reagent kit, is characterized in that, this kit comprises:
Saliva collection bar, connect under the annulus contiguous block that this saliva collection bar connects under comprising handheld terminal, the seal of fixing handheld terminal, seal, annulus contiguous block external diameter down diminish gradually loop connecting block, the plastics connecting link connected under loop connecting block, the plastics connecting link other end the sponge end of the saliva sample collected;
Detect cup, this detection cup comprise containing three joint inspections survey clamps sidewall, can containing receiving the collecting chamber of saliva collection bar and upper cover;
Base, comprises ramped shaped groove, pad and plastic bottom board, and plastic bottom board is welded and fixed with detection cup edge.
2. a kind of saliva three link detection reagent kit as claimed in claim 1, it is characterized in that in described collecting chamber, being provided with two activity bit, one is the first activity bit under sponge end state of nature, described collecting chamber upper end arranges trapezoidal bayonet socket and salient point, and described first activity bit is pinned by trapezoidal bayonet socket and bump; One is the second activity bit after sponge end is extruded.
3. a kind of saliva three link detection reagent kit as claimed in claim 1, is characterized in that described plastics connecting link internal fixtion has dry chemistry reagent bar.
4. a kind of saliva three link detection reagent kit as claimed in claim 2, it is characterized in that described collecting chamber is cylindrical cavity, collecting chamber lower end is semiclosed, and semi-circular opening passes through the ramped shaped groove associating of plastics partition and base.
5. a kind of saliva three link detection reagent kit as claimed in claim 1, it is characterized in that the sidewall of described detection cup is interior and detect clamp containing saliva, three draw-in grooves are provided with in clamp, morphine, meth, ketamine test strip is equipped with respectively in draw-in groove, expose bottom test strips outside clamp, with pad contacts.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201520316900.7U CN204666397U (en) | 2015-05-14 | 2015-05-14 | A kind of saliva three link detection reagent kit |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201520316900.7U CN204666397U (en) | 2015-05-14 | 2015-05-14 | A kind of saliva three link detection reagent kit |
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| CN204666397U true CN204666397U (en) | 2015-09-23 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105527422A (en) * | 2016-01-18 | 2016-04-27 | 北京亦庄国际诊断试剂技术有限公司 | Test paper for three drugs in saliva and preparation method thereof |
| CN106483123A (en) * | 2016-12-12 | 2017-03-08 | 江苏景鹊医疗科技有限公司 | The sampling detecting device with inspection reagent paper for the integration |
| CN108802020A (en) * | 2017-05-05 | 2018-11-13 | 马克西拉博有限公司 | Toxicity detection kit with anti-tamper saliva acquisition system and system of giving counterevidence |
| CN109682873A (en) * | 2019-01-25 | 2019-04-26 | 京东方科技集团股份有限公司 | A kind of saliva detection device and system |
| WO2020206965A1 (en) * | 2019-04-08 | 2020-10-15 | 杭州奥泰生物技术股份有限公司 | Body fluid collection and test device |
-
2015
- 2015-05-14 CN CN201520316900.7U patent/CN204666397U/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105527422A (en) * | 2016-01-18 | 2016-04-27 | 北京亦庄国际诊断试剂技术有限公司 | Test paper for three drugs in saliva and preparation method thereof |
| CN106483123A (en) * | 2016-12-12 | 2017-03-08 | 江苏景鹊医疗科技有限公司 | The sampling detecting device with inspection reagent paper for the integration |
| CN108802020A (en) * | 2017-05-05 | 2018-11-13 | 马克西拉博有限公司 | Toxicity detection kit with anti-tamper saliva acquisition system and system of giving counterevidence |
| CN109682873A (en) * | 2019-01-25 | 2019-04-26 | 京东方科技集团股份有限公司 | A kind of saliva detection device and system |
| WO2020206965A1 (en) * | 2019-04-08 | 2020-10-15 | 杭州奥泰生物技术股份有限公司 | Body fluid collection and test device |
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