CN204649745U - Flat in vitro diagnostic reagent pick-up unit - Google Patents

Flat in vitro diagnostic reagent pick-up unit Download PDF

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Publication number
CN204649745U
CN204649745U CN201520323777.1U CN201520323777U CN204649745U CN 204649745 U CN204649745 U CN 204649745U CN 201520323777 U CN201520323777 U CN 201520323777U CN 204649745 U CN204649745 U CN 204649745U
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flat
reaction bench
microslide
diagnostic reagent
vitro diagnostic
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CN201520323777.1U
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贾江涛
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BEIJING H & J NOVOMED Co Ltd
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BEIJING H & J NOVOMED Co Ltd
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Abstract

The utility model provides a kind of flat in vitro diagnostic reagent pick-up unit, comprises flat body; Its improvements are, this flat body is that polymetylmethacrylate is integrally moulded; One-body molded recessed several reaction bench in this flat body plane, this reaction bench end face is provided with several sample application zone, two inside sidewalls that reaction bench is corresponding are respectively equipped with corresponding loading convex body, and the loading convex body top of the correspondence that two inside sidewalls that this reaction bench is corresponding are respectively equipped with is fitted together to for microslide; Can ensure to detect the synchronization of sample and avoid sample volatilize, can improve the accuracy of detection efficiency and detection simultaneously, this pick-up unit can the microslide of loading different size simultaneously, effectively reduction manual operation cost.

Description

Flat in vitro diagnostic reagent pick-up unit
Technical field
The utility model relates in vitro diagnostic reagent pick-up unit, particularly relates to a kind of flat in vitro diagnostic reagent pick-up unit of antigenic site quality detection.
Background technology
At present, immunology detection technology and products thereof is widely used in numerous detection fields such as great communicable disease, autoimmune disease, tumor markers, food security and prenatal and postnatal care, in indirect immunofluorescence detection experiment, be absolutely necessary by the detection of good antigen matrix to bag, its flat pick-up unit used is absolutely necessary important tool.Current detection matrix is wrapped by certain or certain several antigen in the fixed position of plastic slide or glass slide, often open on slide glass and form the such fixed position of 1-10 part, like this, the synchronous detection of 1-10 patient can be carried out at detection simultaneously, because this type of detection relates to the dilution of patient's sample and manual application of sample, thus length consuming time, poor synchronization and easily dry-out phenomenon occurs, bring many uncertainties to the detection of indirect immunofluorescence, therefore require further improvement.
Utility model content
Fundamental purpose of the present utility model is the above-mentioned shortcoming overcoming existing product existence, and a kind of flat in vitro diagnostic reagent pick-up unit is provided, the synchronization of detection sample can be ensured and avoid sample to volatilize, the accuracy of detection efficiency and detection can be improved simultaneously, this pick-up unit can the microslide of simultaneously loading different size, effectively reduces manual operation cost.
The purpose of this utility model is realized by following technical scheme.
The utility model flat in vitro diagnostic reagent pick-up unit, comprises flat body; It is characterized in that, this flat body is that polymethylmethacrylate (PMMA) is integrally moulded; One-body molded recessed several reaction bench in the plane of this flat body, the end face of this reaction bench is provided with several sample application zone, two inside sidewalls that reaction bench is corresponding are respectively equipped with corresponding loading convex body, and the loading convex body top of the correspondence that two inside sidewalls that this reaction bench is corresponding are respectively equipped with is fitted together to for microslide.
Aforesaid flat in vitro diagnostic reagent pick-up unit, wherein, in described flat body plane, the recessed several reaction bench of one are equidistant setting, and the transversal section of this reaction bench is rectangle, this rectangular length is equal with microslide length, and rectangular width equals microslide width; Several sample application zone that described reaction bench end face is provided with are that double parallel is equidistantly arranged.
Aforesaid flat in vitro diagnostic reagent pick-up unit, wherein, described loading convex body is step convex body, and the height of this step convex body is 1 ± 0.5mm, and the width of step convex body is 2 ± 0.5mm.
Aforesaid flat in vitro diagnostic reagent pick-up unit, wherein, several sample application zone that described reaction bench end face is provided with are the shrinkage pool that the double parallel corresponding with the envelope antigen area size on microslide and position is equidistantly arranged, and the degree of depth of this shrinkage pool is 1 to 0.5mm.
The beneficial effects of the utility model, this pick-up unit can ensure the synchronization and the detection efficiency that detect sample, contacted with the inserted type of reaction bench by microslide, form leakproofness structure, effectively avoid the volatilization of loaded sample, because envelope antigen region on microslide is corresponding with the position detecting sample application zone, can guarantee that antigen and sample effecting reaction improve the accuracy rate detected; Because every block pick-up unit can comprise multiple sample application zone, and each sample application zone is independent setting, thus greatly can improve detection efficiency.
Accompanying drawing explanation
Fig. 1 is the vertical view that the utility model detects board device structure.
Fig. 2 is the crosscut schematic diagram that the utility model detects board device structure.
Fig. 3 is the utility model slide configurations schematic diagram.
Number in the figure illustrates: 1 flat body, 2 postings, 3 reaction bench, 4 sample application zone, 5 loading convex bodys, 6 microslides.
Embodiment
Embodiment 1, as shown in Figure 1 and Figure 2:
The preparation of the utility model flat in vitro diagnostic reagent pick-up unit.
Select polymetylmethacrylate plastics, one-body molded is the length 140mm of rectangular flat plate formula body 1, this rectangular flat plate formula body, width 76mm, thickness 4mm.
Five reaction bench 3 of the recessed equidistant parallel of integrated injection molding in the plane of this rectangular flat plate formula body 1, the distance between two adjacent reaction bench 3 is 2mm, and reaction bench 3 width is 25mm, and length is 76mm; It is that double parallel is equidistantly arranged that the end face of each reaction bench 3 is provided with mutually corresponding 10 sample application zone, 4,10 sample application zone 4 of microslide 6 loading wells size and position; This sample application zone 4 is foursquare shrinkage pool, and the length of side of this shrinkage pool is 6mm, and the degree of depth is 0.5mm; Corresponding two inside sidewalls of reaction bench 3 are provided with step loading convex body 5, and the height of this step convex body 5 is 1 ± 0.5mm, and the width of step convex body 5 is 2 ± 0.5mm; Microslide 6 is placed on step loading convex body 5 that corresponding two inside sidewalls of reaction bench 3 are provided with.
Embodiment 2, as shown in Figure 3:
The use of the utility model flat in vitro diagnostic reagent pick-up unit.
Preparation indirect immunofluorescence detects uses antigen microslide, and its detectable antigens is laryngocarcinoma epithelial cell.
Microslide is that 1mm is thick, and 25mm is wide, and 76mm is long; Wherein, comprise 2 row, 10 reaction zones, reaction zone is the aperture of round diameter 6mm, often arrange reaction zone, the top distance distance from top 19mm, often distance distance from bottom in row bottom reaction zone is 19mm, distance edge, both sides, reaction zone is 4.5mm, and upper and lower reaction zone is parallel spacing 2mm, and reaction zone, left and right is also parallel spacing 4mm.
1, prepare: take out microslide, return to after room temperature until it and cut off packaging.The PBS pulvis distilled water of washing is dissolved to 1L, adds 2ml tween, after mixing, do washing and sample dilutions.
2, dilute: 1:10 dilution done by test serum cleansing solution.
3, application of sample: add the serum harmonizing yinyang contrast of having diluted respectively in the reaction zone that detection is dull and stereotyped, 25 μ l/ holes.Attention: avoid during application of sample producing bubble.
4, hatch: by microslide antigen cover in the dull and stereotyped corresponding sample application zone of detection, incubated at room 30min.Attention: guarantee that each sample all can contact with antigen matrix, and do not contact with each other between sample.
5, wash: take out microslide, from side, reactant liquor is rinsed out gently with cleansing solution, be dipped to and develop a film in cylinder, after leaving standstill 5min, then use distilled water flushing 1 time.
6, application of sample: add fluorescence two and resist in the sample application zone that detection is dull and stereotyped, 25 μ l/ holes.Attention: avoid during application of sample producing bubble.
7, hatch: after paper using wipes antigen slide periphery and reverse side surplus liquid, microslide antigen cover is being detected with in dull and stereotyped corresponding sample application zone, incubated at room 30min.Attention: guarantee that each sample all can contact with antigen matrix, and do not contact with each other between sample.
8, wash: repeat step 5.
9, mounting: drip mountant on the cover slip.After paper using dries antigen slide periphery and reverse side surplus liquid, the antigen matrix of slide glass is placed on ready cover glass down, completes mounting operation.
10, result is observed: observations under fluorescent microscope.
This flat in vitro diagnostic reagent pick-up unit is provided, effectively can ensure the synchronization of detection sample and avoid sample to volatilize, can improve the accuracy of detection efficiency and detection, this pick-up unit can the microslide of loading different size simultaneously, effectively reduces manual operation cost simultaneously.
Be not prior art by the content be described in the present embodiment, therefore no longer repeat.
The above, it is only preferred embodiment of the present utility model, not any pro forma restriction is done to the utility model, every above embodiment is done according to technical spirit of the present utility model any simple modification, equivalent variations and modification, all still belong to technical solutions of the utility model.

Claims (4)

1. a flat in vitro diagnostic reagent pick-up unit, comprises flat body; It is characterized in that, this flat body is that polymethylmethacrylate (PMMA) is integrally moulded; One-body molded recessed several reaction bench (3) in the plane of this flat body (1), the end face of this reaction bench (3) is provided with several sample application zone (4), two inside sidewalls that reaction bench (3) is corresponding are respectively equipped with corresponding loading convex body (5), and loading convex body (5) top of the correspondence that two inside sidewalls that this reaction bench (3) is corresponding are respectively equipped with is fitted together to for microslide (6).
2. flat in vitro diagnostic reagent pick-up unit according to claim 1, it is characterized in that, in described flat body (1) plane, the recessed several reaction bench (3) of one are equidistant setting, the transversal section of this reaction bench (3) is rectangle, this rectangular length is equal with microslide length, and rectangular width equals microslide width; Several sample application zone (4) that described reaction bench (3) end face is provided with equidistantly are arranged for double parallel.
3. flat in vitro diagnostic reagent pick-up unit according to claim 1, is characterized in that, described loading convex body (5) is step convex body, and the height of this step convex body is 1 ± 0.5mm, and the width of step convex body is 2 ± 0.5mm.
4. flat in vitro diagnostic reagent pick-up unit according to claim 1 and 2, it is characterized in that, the shrinkage pool that several sample application zone (4) that described reaction bench (3) end face is provided with equidistantly are arranged for the double parallel corresponding with the envelope antigen area size on microslide (6) and position, the degree of depth of this shrinkage pool is 1 to 0.5mm.
CN201520323777.1U 2015-05-19 2015-05-19 Flat in vitro diagnostic reagent pick-up unit Active CN204649745U (en)

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CN201520323777.1U CN204649745U (en) 2015-05-19 2015-05-19 Flat in vitro diagnostic reagent pick-up unit

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CN204649745U true CN204649745U (en) 2015-09-16

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111426823A (en) * 2020-04-30 2020-07-17 益善生物技术股份有限公司 Reaction cassette for detection and detection operation method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111426823A (en) * 2020-04-30 2020-07-17 益善生物技术股份有限公司 Reaction cassette for detection and detection operation method
CN111426823B (en) * 2020-04-30 2024-08-20 益善生物技术股份有限公司 Reaction box for detection and detection operation method

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