CN204336919U - For detecting the device of organism pulmonary function - Google Patents
For detecting the device of organism pulmonary function Download PDFInfo
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- CN204336919U CN204336919U CN201420617414.4U CN201420617414U CN204336919U CN 204336919 U CN204336919 U CN 204336919U CN 201420617414 U CN201420617414 U CN 201420617414U CN 204336919 U CN204336919 U CN 204336919U
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Abstract
This utility model is the checkout gear about a kind of organism pulmonary function, comprises plethysmography box, animal breath face shield, airflow diversion assembly and the oral cavity flow velocity assembly of placing animal.This checkout gear also comprises breast pressure measurement components, tidal volume measurement components.This utility model can record the multinomial instruction of reaction pulmonary function: breast pressure, oral cavity flow velocity, tidal volume, pulmonary's compliance, airway resistance, and can realize atomized medicine introducing function.Checkout gear disclosed in this utility model, cost is low, easy and simple to handle, the truth of the lung function index reaction animal of detection.
Description
Technical field
This utility model relates to Pulmonary function device, particularly a kind of checkout gear for clear-headed organism pulmonary function.
Background technology
Respiratory tract disease and pulmonary dysfunction disease are the chronic respiratory system diseasess of serious threat human health.In ISUZU company in the past, the crowd that respiratory tract disease and pulmonary dysfunction disease are suffered from by western countries increases significantly, and this is mainly attributed to urbanization and changing diet and life style.Simultaneously the popularity of respiratory tract disease and pulmonary function disease, M & M are also increase year by year, in the prevalence of China also in ascendant trend year by year.Correlational study shows, pulmonary function test can be evaluated respiratory tract disease and pulmonary dysfunction disease, assesses the drug effect of its medicine simultaneously, is conducive to playing good assosting effect to the respiratory disorder order of severity of patient and the selection of medicine.
All medicines, before entering human trial, first will carry out drug effect, pharmacology and toxicological test in animals, guarantee that this medicine is not when having great side effect to human body, play a positive role to disease therapy.Wherein, in the effect experiment of respiratory drugs, what often adopt is anesthetized animal, because anesthetized animal has simple to operate comparatively speaking, and the advantage that expense is less.But no matter because the chemical composition of anaesthetic has a great impact the tool of animal own, cause the change of every physical signs, be therefore administration of anaesthesia or binding administration, measured physiological parameter all can not go out the physiological parameter of animal by accurate response.
This utility model is the test carrying out lung function index under animal waking state.Box technology is traced, as " the reactive non-intrusion type new method of the calm rat airway of a kind of measurement " of Wei Erqing based on existing closed volume
1., what use in literary composition is that the sealed volume of rat traces case method, but the method is whole animal to be positioned in chest, and the gas that the tidal volume of such animal and oral cavity are breathed then can interfere with each other.The method does not record the intrathoracic pressure of animal simultaneously, cannot try to achieve the key index of lung function, i.e. airway resistance and lung compliance.
" the Tidal midexpiratory flow as a measure of airway hyperresponsiveness in allergic mice " of THOMAS GLAAB
2.the two-chamber plethysmography box method of middle employing, its system can be good at tidal volume being detected, is relatively stable detection system.But still there is the problem that data are incomplete, what its adopted is that the method for thoracic cavity interpolation pipe records intrathoracic pressure, directly inserts in animal body by conduit, directly can cause the pain of animal, may cause unknown stimulating factor to animal; In addition, this system can not record the oral cavity flow velocity of sobering animal, therefore also cannot obtain this key index of airway resistance.
With this utility model dependency larger be " the A novel method for chronic measurement of respiratory function in theconscious monkey " that Dennis J.Murphyf delivers
3., in the method, the oral cavity flow velocity of animal is undertaken converting by the pressure transducer in a whole body plethysmography box, and the gas and the abdominal cavity that includes animal oral cavity breathing change the gas extruded in chest.First from essence, animal oral cavity breathe gas and abdominal cavity change extruding chest in gas be contrary relation, the method by both and be equal to thoracic cavity change value, there is very large problem.Oral cavity flow velocity only represents the gas breathed in animal oral cavity, can not the relation of computing with tidal volume.Next, between the two also because the time difference occurred, thus there is a phase contrast, the change meeting slim lead of oral cavity flow velocity is in the change of thoracic cavity volume, and therefore in the method, the calculating of oral cavity flow velocity is inaccurate.Meanwhile, in the method, the tidal volume of animal is the electrode by being fixed on animal thoracic cavity, and the change when stretching in thoracic cavity between electrode causes the change of impedance to carry out converting, and therefore the method can not obtain the real tidal volume values of animal in plethysmography box.In addition, there is not atomized medicine introducing system in this system, just verified system by simple stimulus object, and do not have function pulmonary function medicine being detected to drug effect, therefore this system still exists larger deficiency, and application is very restricted.
Therefore, technology about sobering animal lung function method has several, but the existing system not having the direct physiology of respiration parameter of Overall Acquisition on the market, do not have and accurately can obtain airway resistance yet, accurately lung compliance can be detected again, simultaneously also by various administering mode, and to the device of animal bronchodilator effect detection and application technology after finally obtaining administration.
Because the defect that above-mentioned existing sobering animal lung function device exists, the present inventor based on practical experience and Professional knowledge, and coordinates the utilization of scientific principle, actively in addition research and innovation, to founding a kind of sobering animal lung function device, it is made to have more practicality.
This utility model, for the deficiencies in the prior art, devises a kind of sobering animal lung function device, can react animal real physiological parameter, can measure multiple index, comprise intrathoracic pressure, oral cavity gas flow rate and tidal volume, and can realize administration functions.
Utility model content
This utility model main purpose is, the physiological parameter overcoming measured pulmonary function when organism (animal) administration of anaesthesia or binding administration can not go out the defect of the real physiological parameter of animal by accurate response, and a kind of device for detecting organism pulmonary function is newly provided, it utilizes plethysmography box to fix animal, regain consciousness animal, relatively freely and under not being in high-strung state, carry out the oral cavity flow velocity measuring sobering animal, intrathoracic pressure and tidal volume, thus the relevant parameters of Obtaining Accurate organism (animal) pulmonary function, thus be more suitable for practicality, and the value had in industry.
Another object of the present utility model is, provides a kind of device for detecting organism pulmonary function, and technical problem to be solved is detecting organism pulmonary function while, realizes in the mode of atomized medicine introducing to organism administration, thus is more suitable for practicality.
Another main purpose of the present utility model is, the perforate traced on box body connects steam hose, and ventilation software connects flow sensor, flow sensor connection signal transducer, signal adapter connecting multi-channel Physiological Signal Acquiring System.Record cabinet interior and the flow velocity of extraneous exchanging gas, can tidal volume be obtained by the integration of flow velocity.
The purpose of this utility model and solve its technical problem and realize by the following technical solutions.According to a kind of device for detecting organism pulmonary function that the utility model proposes, it comprise placement and fixed biologically body plethysmography box, for organism breathing mask, comprise the airflow diversion assembly of expiration pipeline and suction line, and for detecting the assembly of organism oral cavity flow velocity; The breathing mask described in the connection of one end of described airflow diversion assembly, the assembly for detecting organism oral cavity flow velocity described in other end connection of described airflow diversion assembly.
The purpose of this utility model and solve its technical problem and also can be applied to the following technical measures to achieve further.
The aforesaid device for detecting organism pulmonary function, it comprises atomized medicine introducing assembly further, this atomized medicine introducing assembly comprises nebulizer and shower nozzle, and one end of described atomized medicine introducing assembly is connected by the suction line of shower nozzle with described airflow diversion assembly, and its other end is connected with nebulizer.
The aforesaid device for detecting organism pulmonary function, wherein said plethysmography box comprise hold organism trunk casing, for organism head exposure retouched the cervical region fixing seal assembly of meter case in described volume and is used for protecgulum and the bonnet of seal case.The protecgulum of wherein said casing is the direction setting of organism cervical region side, and rear cover of box is arranged on the opposite side of organism, namely relative with protecgulum side.
The aforesaid device for detecting organism pulmonary function, wherein said cervical region fixing seal assembly comprises the sealed bolster or diaphragm seal that prevent cervical region from leaking gas.
The aforesaid device for detecting organism pulmonary function, the suction line of wherein said airflow diversion assembly is communicated with air supply system and/or atomized medicine introducing assembly, its expiration pipeline is provided with valve with the connecting pipeline of the assembly for detecting organism oral cavity flow velocity, described valve is closed when organism air-breathing, opens when organism is exhaled; Wherein, the gas that described air supply system provides comprises medical oxygen, air and/or carbon dioxide.
The aforesaid device for detecting organism pulmonary function, wherein said comprises flow sensor and multi-Channel Physiological Signal Acquiring System for the assembly detecting organism oral cavity flow velocity, and the signal adapter be connected with described flow sensor and described multi-Channel Physiological Signal Acquiring System.
The aforesaid device for detecting organism pulmonary function, wherein, a perforate is established in the front end (protecgulum) of the casing of plethysmography box, connect steam hose, steam hose connects flow sensor, flow sensor connection signal transducer, signal adapter connecting multi-channel Physiological Signal Acquiring System.
The aforesaid device for detecting organism pulmonary function, wherein comprises the implanted device in implantable bioartificial body and/or the intravenous injection assembly for organism neck injection further; Described implanted device is ITS remote measurement implanted device, and one end of ITS remote measurement main control system connects ITS signal receiving antenna, other end connecting multi-channel Physiological Signal Acquiring System.
The aforesaid device for detecting organism pulmonary function, wherein said organism is in Normal Conscious state when testing, and described organism is selected from Canidae, Primates, horse or people.
The aforesaid device for detecting organism pulmonary function, wherein this device comprises intrathoracic pressure test suite, oral cavity flow velocity test suite and tidal volume test suite.
The aforesaid device for detecting organism pulmonary function, wherein: described intrathoracic pressure test suite comprises ITS remote measurement implanted device, ITS remote measurement main control system, ITS signal receiving antenna and multi-Channel Physiological Signal Acquiring System, the ITS signal receiving antenna described in the connection of one end of described ITS remote measurement main control system, the multi-Channel Physiological Signal Acquiring System described in its other end connects; Described oral cavity flow velocity test suite comprises the airflow diversion assembly be made up of expiration pipeline and suction line, the flow sensor, the multi-Channel Physiological Signal Acquiring System that are connected with expiration pipeline, and the signal adapter be connected with described flow sensor and described multi-Channel Physiological Signal Acquiring System; Described tidal volume test suite comprise placement and fixed biologically body plethysmography box, for organism breathing mask, comprise the airflow diversion assembly of expiration pipeline and suction line; Wherein, the front end of the casing of plethysmography box is established a perforate, connect steam hose, steam hose connects flow sensor, flow sensor connection signal transducer, signal adapter connecting multi-channel Physiological Signal Acquiring System.
The aforesaid device for detecting organism pulmonary function, it comprises atomized medicine introducing assembly further, this atomized medicine introducing assembly comprises nebulizer and shower nozzle, and one end of described atomized medicine introducing assembly is connected by the suction line of shower nozzle with described airflow diversion assembly, and its other end is connected with nebulizer.
This utility model compared with prior art has obvious advantage and beneficial effect.From above technical scheme, in order to reach aforementioned utility model object, main technical content of the present utility model is as follows:
In one embodiment, wherein the measurement of intrathoracic pressure is realized by telemetry, implanted device is surgically implanted in animal body, the intrathoracic pressure of animal is obtained by wireless signal, instead of undertaken by the method for the pleura contact pin having wound, because the method for contact pin can not be used in sobering animal, on especially clear-headed large animal.Oral cavity flow velocity, by a face shield, face shield adds flow sensor is measured.While velocity measurement, also need to ensure that the normal oxygen supply of animal does not go wrong, the dead space of mask conduit is relatively little.Tidal volume realizes by connecting a flow sensor in chest, because other parts of cabinet interior are sealings, gas only by the breathing turnover plethysmography box of unique passage along with animal, therefore can carry out to flow sensor the tidal volume that integration can obtain chest.
While obtaining three important physiology of respiration parameters, electrocardiosignal and the temperature signals of animal can also be obtained.In addition, also must ensure that animal is when velocity measurement, the amount of oxygen of face masks is enough, and animal can not anoxia and cause its physiological parameter to change.When atomized medicine introducing, medicine can be tried one's best and many be sucked in lung by animal, and the carbon dioxide that animal is breathed out simultaneously can discharge face shield again, can not gather in face masks.Very objectively can obtain the important parameter of pulmonary function and derive and obtain airway resistance and the lung compliance of animal, instead of obtained by simulation or other complex calculation, its numerical value has very strong intuitive and derivation property.This device can also realize atomized medicine introducing simultaneously, can meet the needs surveying oral cavity flow velocity and atomized medicine introducing, plays an important role in animal lung function detects.
In one embodiment, in order to the partial fixing realized beyond animal head cervical region is traced in case what seal, place animal and trace case at interior, comprise casing, there is a circular hole casing front portion, ensures that the head of animal can reach chest outside by circular hole, comprise seal with elastometic washer formula bonnet, comprise cervical region and fix protecgulum, the diameter of protecgulum top inner circle perforate is more bigger than the diameter of animal neck, less than the diameter of animal head.Also comprise the sealed bolster or diaphragm seal that prevent cervical region from leaking gas.
In one embodiment, when measuring oral cavity flow velocity, install face shield additional by animal mouth, connect airflow diversion assembly outside face shield, airflow diversion assembly has 4 ports, and a port connects face shield, an air inlet port, an administration port, an expiration detection port.Expiration detection port place closes when being provided with animal air-breathing, " valve " opened during expiration, thus as much as possible allow animal oxygen intake and or atomization medicine, open when expiration, ensure CO in face shield
2discharge.Airflow diversion assembly inlet end connects the equipment providing air or oxygen, and expiration test side connects flow sensor, and flow sensor connection signal transducer, multi-Channel Physiological Signal Acquiring System is connected with signal adapter.The air splitter means administration port closed when oral cavity flow rate detection.Real oral cavity flow parameters can be measured like this.When carrying out atomized medicine introducing, administration port connects nebulizer, and the flow sensor be connected with expiration test side is closed.Can stop atomization medicine after animal breath to abundant medicine, handle assembly switches to the state measuring oral cavity flow velocity.After waiting for that animal pharmaceuticals reacts a period of time, namely measure the pulmonary function situation of now animal by clear-headed large animal lung function detection system.
In one embodiment, the measurement of intrathoracic pressure is realized by telemetry, traces in the animal body in case and implants ITS remote measurement implanted device in advance, and ITS remote measurement main control system one end connects ITS signal receiving antenna, other end connecting multi-channel Physiological Signal Acquiring System.The intrathoracic pressure of animal is recorded by wireless signal.Under animal relaxation state, instead of by there being the method for the pleura contact pin of wound to carry out under the state of animal anxiety.
Through from the above, this utility model is checkout gear about a kind of organism pulmonary function and using method, comprises plethysmography box, animal breath face shield, airflow diversion assembly and the oral cavity flow velocity assembly of placing animal.This checkout gear also comprises breast pressure measurement components, tidal volume measurement components.The multinomial instruction of reaction pulmonary function can be recorded: breast pressure, oral cavity flow velocity, tidal volume, pulmonary's compliance, airway resistance, and atomized medicine introducing function can be realized.Described checkout gear, cost is low, easy and simple to handle, the truth of the lung function index reaction animal of detection.
By technique scheme, this utility model at least has following advantages for the device detecting organism pulmonary function:
It is low that this checkout gear has cost, and than being easier to operation, measurement index can react truth, and realizes drug-supplying system function.Intrathoracic pressure, oral cavity flow velocity, tidal volume, airway resistance and lung compliance can be detected, can also atomized medicine introducing be carried out simultaneously, the measurement to animal bronchodilator effect after acquisition administration.
In sum, the device for detecting organism pulmonary function that this utility model is special, it has above-mentioned many advantages and practical value, and publish there are no similar design or use in like product and really belong to innovation, no matter it is in method or functionally all have larger improvement, have large improvement technically, and create handy and practical effect, and the more existing device for detecting organism pulmonary function has multinomial effect of enhancement, thus be more suitable for practicality, and there is the extensive value of industry, it is really a novelty, progressive, practical new design.
Above-mentioned explanation is only the general introduction of technical solutions of the utility model, in order to better understand technological means of the present utility model, and can be implemented according to the content of description, coordinates accompanying drawing to be described in detail as follows below with preferred embodiment of the present utility model.
Accompanying drawing explanation
What Fig. 1 showed is sobering animal lung function device operating diagram.
Schematic diagram when what Fig. 2 showed is oral cavity flow component measurement.
Schematic diagram when what Fig. 3 showed is oral cavity flow component atomized medicine introducing.
In figure: animal breath part can be divided into 1,2,3,4 four path, and 1 path has air inlet port, and 2 paths have administration port, 3 paths have expiration detection port, 4 access ports connect face shield; 5 is air feed equipment, and gas is medical oxygen, or air; 6 is nebulizer; 7 is signal adapter, and flow velocity signal is converted to the signal of telecommunication; 8 is multi-Channel Physiological Signal Acquiring System; 9 is ITS remote measurement main control system; 10 is signal adapter, and flow velocity signal is converted to the signal of telecommunication; 11 is ITS signal receiving antennas; 12 is ITS remote measurement implanted devices; 13 is trace case bonnet; 14 is injecting systems.
Detailed description of the invention
For further setting forth apparatus structure, feature using method and effect that this utility model is taked for reaching predetermined utility model object, below in conjunction with accompanying drawing and preferred embodiment, to the clear-headed large animal lung function checkout gear that the utility model proposes and using method thereof, be described in detail.
Relational language defines:
Intrathoracic pressure: intrathoracic pressure, also known as intrapleural pressure or intrapleural pressure, refers to the pressure in the potential chamber (i.e. pleural space) between visceral pleura and parietal pleura.
Oral cavity flow velocity: the flow of gas when breathing from respiratory tract (nose or oral cavity).
Tidal volume: the tolerance sucking at every turn or breathe out when referring to eupnea.
Remote measurement: the close-in measurement value of object parametric is transferred to remote measuring station to realize the technology of telemeasurement.
Animal remote measurement: the measuring technique physiological parameter of animal being wirelessly sent to the receptor outside animal body.
Plethysmography box: be a kind of instrument measuring organ or the change of whole body size.
The abbreviation of ITS:ITS and Integrate telemetry system, it is the laboratory animal wireless remote-measuring system that Konigsberg company and RMISS company develop cooperatively.Compared with implantation telemetry system, vest type remote measurement has hurtless measure, does not need operation and the convalescence after Miles operation, saves time and expense, meet animal welfare requirement, wear vest to animal, stress not wait remarkable advantage to animal.
Airway resistance: airway resistance=intrathoracic pressure/oral cavity flow velocity.
Lung compliance: lung compliance=tidal volume/intrathoracic pressure.
As shown in Figure 1, this utility model checkout gear comprises one and places the plethysmography box of animal, animal breath face shield (shown in figure conic section) and airflow diversion assembly.Plethysmography box comprises seal with elastometic washer formula bonnet 13, cervical region fixed part 14.Tidal volume measurement module comprises the steam hose being communicated with and tracing case, flow velocity signal is converted to the signal adapter of the signal of telecommunication, and this signal adapter one end connects plastic flexible pipe, other end connecting multi-channel Physiological Signal Acquiring System.Breast pressure measurement module comprises the ITS remote measurement implanted device in animal body, and ITS remote measurement main control system one end connects ITS signal receiving antenna, other end connecting multi-channel Physiological Signal Acquiring System.Airflow diversion assembly has 1,2,3,4 four port path, and 1 port enters oxygen or air 2 port atomized medicine introducing, and 3 ports are animal exhalation path, 4 ports connect face shield, animal air-breathing.When surveying oral cavity flow velocity, 1 path keeps oxygen path, avoids Animal Anoxia, 2 path sealings, avoid the oxygen entered by 1 path to be discharged in air, and 3 paths connect upper flow sensor measures oral cavity flow velocity, 4 paths connect breathing mask, and animal breathes from breathing mask.
When surveying oral cavity flow velocity, 1 path keeps oxygen path, avoids Animal Anoxia, 2 path sealings, avoid the oxygen entered by 1 path to be discharged in air, and 3 paths connect upper flow sensor measures oral cavity flow velocity, 4 paths connect breathing mask, and animal is breathed by breathing mask.
When carrying out atomized medicine introducing, 1 path still keeps oxygen path, avoid Animal Anoxia, 2 paths then connect atomizer, shower nozzle connects nebulizer, and medicine sprays in face shield from atomizer through 2 paths, and 3 paths then access " valve " of an one direction ventilation, this valve can ensure that animal is closed when air-breathing, thus can suck the atomization medicine entered by 2 paths as much as possible; Open when expiration, ensure the discharge of CO2 in face shield, avoid animal to cause the change of lung function parameter because of anoxia; 4 paths connect breathing mask, and animal breathes from breathing mask.
The operating procedure of clear-headed large animal lung function checkout gear is as follows:
(1) intrathoracic pressure is measured.
Implanted device was embedded in animal body in 7 days in advance, wait for the intrathoracic pressure directly being recorded animal after animal returns to one's perfect health by the implanted device in body, can avoid because directly penetrate into the thoracic cavity of animal with needle-like sensor like this, ANIMAL PAIN and the anxiety that causes and resistance, cause measurement data untrue.Animal breast pressure is by the ITS remote measurement implanted device in animal body, and remote measurement main control system, remote measurement main control system one end connects ITS signal receiving antenna, other end connecting multi-channel Physiological Signal Acquiring System.
(2) at animal neck reserved intravenous injection indwelling tube with it.
(3) the neck place diaphragm seal of animal is wound around, and ensures the phenomenon that there is not gas leakage between sealing bag and neck; Or use cushion film encapsulation process.
(4) animal guiding is entered plethysmography box, the bonnet tracing case is covered, and animal can be popped one's head in out from the outlet tracing case front end.Animal is left standstill with prostrate posture in chest, around bonnet, has several buckles, by buckle, bonnet is fixed, ensure that bonnet tightly can be pressed in the rear portion of chest.Simultaneously bonnet has a circle white latex, latex receives extruding can produce deformation, and it has elastic feature can ensure that junction does not have space, to ensure that the sealing of chest.
(5) installation is traced case front end animal neck and is fixed protecgulum, the opening that cervical region is fixed on protecgulum diameter of bore is less than the head of animal, but slightly larger than the neck sizes of animal, therefore can be fixed animal, fixing head can play suitable fixation to animal, animal can not be had influence on again breathe normally, and ensure to trace case sealing.
(6) oral cavity flow velocity is measured
By powerlab data acquisition and analysis system, obtain gas flow during animal breath, also namely obtain oral cavity flow velocity.
When measuring oral cavity flow velocity, when surveying oral cavity flow velocity, 1 path keeps oxygen path, avoid Animal Anoxia, 2 path sealings, avoid the oxygen entered by 1 path to be discharged in air, and 3 paths connect upper flow sensor measures oral cavity flow velocity, 4 paths connect breathing mask, and animal breathes from breathing mask; Now stimulate to animal injection, the pulmonary function situation of animal can be reflected by clear-headed large animal lung function detection system.
(7) when carrying out atomized medicine introducing, 1 path still keeps oxygen path, avoid Animal Anoxia, 2 paths then connect atomizer, and shower nozzle connects nebulizer, and medicine sprays in face shield from atomizer through 2 paths, 3 paths then remove flow sensor, access the device of an one direction ventilation, this device can ensure that animal is closed when air-breathing, thus can suck the atomization medicine entered by 2 paths as much as possible; Open when expiration, ensure the discharge of CO2 in face shield, avoid animal to cause the change of lung function parameter because of anoxia; 4 paths connect breathing mask, and animal breathes from breathing mask; Can stop atomization medicine after animal breath to abundant medicine, handle assembly switches to the state measuring oral cavity flow velocity.
(8) after waiting for that animal pharmaceuticals reacts a period of time, again giving animal stimulates, and namely measures the pulmonary function situation of now animal by clear-headed large animal lung function detection system.
(9), after device installs, thermometer on cabinet interior is placed, can observe the temperature of cabinet interior.Meanwhile, put heat sink at the top of plethysmography box, avoid because the body temperature of animal self causes the temperature of gas in chest to raise, thus cause pressure to become the generation of the phenomenons such as large and other influences animal breath.
(10), after preparation terminates, the central venous catheter namely reserved with it by animal carries out administration.Owing to being carry out sobering animal experiment, therefore needing to extend with stilligout, outside the visual field of animal, carry out the injection of venous stimulation thing, avoid because artificial origin affects the physiological status of animal.
The above, it is only preferred embodiment of the present utility model, not any type of restriction is done to this utility model, although this utility model discloses as above with preferred embodiment, but and be not used to limit this utility model, any those skilled in the art, do not departing within the scope of technical solutions of the utility model, when the method and technology contents that can utilize above-mentioned announcement are made a little change or be modified to the Equivalent embodiments of equivalent variations, in every case be the content not departing from technical solutions of the utility model, according to any simple modification that technical spirit of the present utility model is done above embodiment, equivalent variations and modification, all still belong in the scope of technical solutions of the utility model.
List of references:
1. the clear Tian Jiongchen of Wei Er amasss fervent Zhang Weiping. the reactive non-intrusion type new method of the calm rat airway of a kind of measurement. and Journal of physiology, 1997,49 (4), 471 1 474.
②THOMAS GLAAB,ANGELIKA DASER,ARMIN BRAUN.Tidal midexpiratory flow as a measure of airway hyperresponsiveness in allergic mice.Am J Physiol Lung Cell Mol Physiol280:L565–L573,2001.
③Dennis J.Murphy,Jonathan P.Renninger.A novel method for chronic measurement of respiratory function in theconscious monkey.Journal of Pharmacological and Toxicological Methods46(2001)13–20.
Claims (12)
1. one kind for detecting the device of organism pulmonary function, it comprise placement and fixed biologically body plethysmography box, for organism breathing mask, comprise the airflow diversion assembly of expiration pipeline and suction line, and for detecting the assembly of organism oral cavity flow velocity; The breathing mask described in the connection of one end of described airflow diversion assembly, the assembly for detecting organism oral cavity flow velocity described in other end connection of described airflow diversion assembly.
2. the device for detecting organism pulmonary function according to claim 1, it comprises atomized medicine introducing assembly further, this atomized medicine introducing assembly comprises nebulizer and shower nozzle, one end of described atomized medicine introducing assembly is connected by the suction line of shower nozzle with described airflow diversion assembly, and its other end is connected with nebulizer.
3. the device for detecting organism pulmonary function according to claim 1 and 2, wherein said plethysmography box comprise hold organism trunk casing, for organism head exposure retouched the cervical region fixing seal assembly of meter case in described volume and is used for protecgulum and the bonnet of seal case.
4. the device for detecting organism pulmonary function according to claim 3, wherein said cervical region fixing seal assembly comprises the sealed bolster or diaphragm seal that prevent cervical region from leaking gas.
5. the device for detecting organism pulmonary function according to claim 1 and 2, the suction line of wherein said airflow diversion assembly is communicated with air supply system and/or atomized medicine introducing assembly, its expiration pipeline is provided with valve with the connecting pipeline of the assembly for detecting organism oral cavity flow velocity, described valve is closed when organism air-breathing, opens when organism is exhaled; Wherein, the gas that described air supply system provides comprises medical oxygen, air and/or carbon dioxide.
6. the device for detecting organism pulmonary function according to claim 5, wherein said comprises flow sensor and multi-Channel Physiological Signal Acquiring System for the assembly detecting organism oral cavity flow velocity, and the signal adapter be connected with described flow sensor and described multi-Channel Physiological Signal Acquiring System.
7. the device for detecting organism pulmonary function according to claim 6, wherein, the front end of the casing of plethysmography box is established a perforate, connect steam hose, steam hose connects flow sensor, flow sensor connection signal transducer, signal adapter connecting multi-channel Physiological Signal Acquiring System.
8. the device for detecting organism pulmonary function according to claim 1 and 2, wherein comprises the implanted device in implantable bioartificial body and/or the intravenous injection assembly for organism neck injection further; Described implanted device is ITS remote measurement implanted device, and one end of ITS remote measurement main control system connects ITS signal receiving antenna, other end connecting multi-channel Physiological Signal Acquiring System.
9. the device for detecting organism pulmonary function according to claim 1 and 2, wherein this device also comprises intrathoracic pressure test suite, oral cavity flow velocity test suite and tidal volume test suite.
10. the device for detecting organism pulmonary function according to claim 9, wherein:
Described intrathoracic pressure test suite comprises ITS remote measurement implanted device, ITS remote measurement main control system, ITS signal receiving antenna and multi-Channel Physiological Signal Acquiring System, the ITS signal receiving antenna described in the connection of one end of described ITS remote measurement main control system, the multi-Channel Physiological Signal Acquiring System described in its other end connects;
Described oral cavity flow velocity test suite comprises the airflow diversion assembly be made up of expiration pipeline and suction line, the flow sensor, the multi-Channel Physiological Signal Acquiring System that are connected with expiration pipeline, and the signal adapter be connected with described flow sensor and described multi-Channel Physiological Signal Acquiring System;
Described tidal volume test suite comprise placement and fixed biologically body plethysmography box, for organism breathing mask, comprise the airflow diversion assembly of expiration pipeline and suction line; Wherein, the front end of the casing of plethysmography box is established a perforate, connect steam hose, steam hose connects flow sensor, flow sensor connection signal transducer, signal adapter connecting multi-channel Physiological Signal Acquiring System.
11. devices for detecting organism pulmonary function according to claim 10, it comprises atomized medicine introducing assembly further, this atomized medicine introducing assembly comprises nebulizer and shower nozzle, one end of described atomized medicine introducing assembly is connected by the suction line of shower nozzle with described airflow diversion assembly, and its other end is connected with nebulizer.
12. devices for detecting organism pulmonary function according to claim 10, are provided with the thermometer for monitoring box body temperature and the temperature-adjusting device controlling casing problem in wherein said plethysmography box.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104305997A (en) * | 2014-08-21 | 2015-01-28 | 华南理工大学 | Device for detecting pulmonary function of creatures |
| CN110503870A (en) * | 2018-05-18 | 2019-11-26 | 斯波瑞申有限公司（以奥林巴斯呼吸美国名义） | Breathe lung device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104305997A (en) * | 2014-08-21 | 2015-01-28 | 华南理工大学 | Device for detecting pulmonary function of creatures |
| CN110503870A (en) * | 2018-05-18 | 2019-11-26 | 斯波瑞申有限公司（以奥林巴斯呼吸美国名义） | Breathe lung device |
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