CN204325332U - A kind of gel device for cutting automatically - Google Patents
A kind of gel device for cutting automatically Download PDFInfo
- Publication number
- CN204325332U CN204325332U CN201420667804.2U CN201420667804U CN204325332U CN 204325332 U CN204325332 U CN 204325332U CN 201420667804 U CN201420667804 U CN 201420667804U CN 204325332 U CN204325332 U CN 204325332U
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- axis
- guide rail
- slide block
- gel
- cutting
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Abstract
The utility model relates to a kind of gel device for cutting automatically, belongs to biotechnology apparatus field.Stage microscope is provided with to bottom in the gel imaging instrument shell of automatic gel device for cutting, cut in glue cutters layout sliding support structure, cut glue cutter by the drive of sliding support structure to move in gel imaging instrument shell, CCD digital camera is arranged in gel imaging instrument housing top end and gathers sampling pattern, and CCD digital camera is connected with computer.The automatic gel device for cutting that the utility model provides utilizes the imaging technique of gel imaging instrument autologous adult, add three-dimensional motion control techniques and the image processing techniques of micro-chip and PC combination, the mechanical arm of ingehious design, realize the location to object fragment, cutting and loading specified containers, realize the human body touch free operation of whole process, when avoiding manually cutting glue, ultraviolet and nucleic acid dye are to the injury of human body, make the work of cutting glue become accurately simple and quick simultaneously.
Description
Technical field
The utility model relates to a kind of gel device for cutting automatically, belongs to biotechnology apparatus field.
Background technology
Current DNA gel band all passes through manually to cut under uviolizing when reclaiming, there is many drawbacks in this kind of method: is first that the nucleic acid dyes such as EB may exist carcinogenic danger to human body, next is that DNA molecular easily suddenlys change under uviolizing, to such an extent as to cause the mistake of subsequent experimental result, there is larger error when being hand-cut again.And for the cut work of two-dimentional gel before doing Mass Spectrometric Identification, often measure larger, and require precisely, to cause operational difficulty like this.
Utility model content
The utility model provides a kind of gel device for cutting automatically for above-mentioned deficiency.
the utility model adopts following technical scheme:
Automatic gel device for cutting described in the utility model, comprises Stage microscope, cuts glue cutter, CCD digital camera, gel imaging instrument shell, sliding support structure, computer; Stage microscope is provided with to bottom in described gel imaging instrument shell, cut in glue cutters layout sliding support structure, cut glue cutter by the drive of sliding support structure to move in gel imaging instrument shell, CCD digital camera is arranged in gel imaging instrument housing top end and gathers sampling pattern, and CCD digital camera is connected with computer.
Automatic gel device for cutting described in the utility model, described sliding support structure comprises Z axis screw mandrel, Z axis lead rail axis, Y-axis guide rail, X-axis guide rail, Z axis servomotor, X-axis slide block, Y-axis slide block, Y-axis screw mandrel, Y-axis servomotor, X-axis servomotor, Z axis slide block, X-axis screw mandrel;
In the enclosure, Y-axis slide block is arranged on Y-axis guide rail and along the side-to-side movement of Y-axis guide rail, Y-axis feed screw nut is fixed on Y-axis slide block, is connected with Y-axis servomotor by Y-axis screw mandrel for described Y-axis guide rail and the fixed installation of Y-axis servomotor; The rotating drive Y-axis screw mandrel of Y-axis servomotor rotates and drives the side-to-side movement of Y-axis slide block;
Described X-axis guide rail is fixed on Y-axis slide block vertical with Y-axis guide rail, can with the side-to-side movement of Y-axis slide block; X-axis servomotor is fixed on X-axis guide rail rear end, and X-axis slide block is arranged on X-axis guide rail, and seesaws along X-axis guide rail, and X-axis driven by servomotor X-axis screw mandrel rotates and drives X-axis slide block to seesaw.
Described Z axis guide rail is fixed on X-axis slide block, vertical with X lead rail axis, can seesaw with X-axis slide block.Z axis servomotor is fixedly mounted on Z axis guide rail upper end, and Z axis slide block to be arranged on X-axis guide rail and to move up and down along Z axis guide rail; The driving Z axis screw mandrel of Z axis servomotor rotates and drives Z axis slide block to move up and down and can simultaneously with the side-to-side movement of X-axis guide rail.
Automatic gel device for cutting described in the utility model, also comprises cutter conversion motor, and described cutter conversion motor is arranged on Z axis slide block, cuts glue cutter and cutter conversion motor, and cutter conversion motor rotates drive and cuts the rotation of glue cutter.
Automatic gel device for cutting described in the utility model, Stage microscope is provided with gel collection container putting hole, for placing experimenter for collecting the container of object gel piece.
beneficial effect
The automatic gel device for cutting that the utility model provides utilizes the imaging technique of gel imaging instrument autologous adult, add three-dimensional motion control techniques and the image processing techniques of micro-chip and PC combination, the mechanical arm of ingehious design, realize the location to object fragment, cutting and loading specified containers, realize the human body touch free operation of whole process, when avoiding manually cutting glue, ultraviolet and nucleic acid dye are to the injury of human body, make the work of cutting glue become accurately simple and quick simultaneously.
The utility model has used micro-chip Graph Control technology, utilizes IMAQ software and hardware system to gather gel images, obtains the data of gel location, and control topworks and carry out cutting of object fragment accurately according to image analysis.
Accompanying drawing explanation
Fig. 1 is structural representation just of the present utility model;
Fig. 2 is side-looking structural representation of the present utility model
Fig. 3 of the present utility modelly cuts glue cutter schematic diagram;
Fig. 4 is carrier structure schematic diagram of the present utility model;
Fig. 5 is control module schematic diagram of the present utility model.
In figure, 1 is Stage microscope, and 2 is cut glue cutter, and 3 is Z axis screw mandrels, 4 is Z axis lead rail axis, and 5 is Y-axis guide rails, and 6 is X-axis guide rails, 7 is Z axis servomotors, and 8 is CCD digital cameras, and 9 is gel imaging instrument shells, 10 is X-axis slide blocks, and 11 is Y-axis slide blocks, and 12 is Y-axis screw mandrels, 13 is Y-axis servomotors, 14 Y-axis feed screw nuts, 15 is X-axis servomotors, and 16 is Z axis slide blocks, 17 is cutter conversion motors, 18 is gel collection container putting holes, and 19 is motor shafts, and 20 is Z axis nuts, 21 is computers, 22 is X-axis nuts, and 23 is X-axis screw mandrels, and 24 is sterilization pools.
Embodiment
Tuberculosis accompanying drawing further describes the utility model below:
Stage microscope 1 is provided with to bottom in the gel imaging instrument shell 9 of automatic gel device for cutting, cutting glue cutter 2 arranges in sliding support structure, cut glue cutter 2 by the drive of sliding support structure to move in gel imaging instrument shell 9, CCD digital camera 8 is arranged in gel imaging instrument shell 9 top and gathers sampling pattern, and CCD digital camera 8 is connected with computer 21.
This device also comprises Z axis screw mandrel 3, Z axis lead rail axis 4, Y-axis guide rail 5, X-axis guide rail 6, Z axis servomotor 7, X-axis slide block 10, Y-axis slide block 11, Y-axis screw mandrel 12, Y-axis servomotor 13, is fixed on the Y-axis feed screw nut 14 on Y-axis slide block, X-axis servomotor 15, Z axis slide block 16, cutter conversion motor 17, gel collection container putting hole 18 on Stage microscope, cutter conversioning wheel and motor coupling shaft 19, Z axis feed screw nut 20, X-axis feed screw nut 22, X-axis screw mandrel 23, sterilization pool 24;
Described Y-axis guide rail 5 and Y-axis servomotor 13 are fixedly mounted on the upper of shell 9 inner back wall, Y-axis slide block 11 is arranged on Y-axis guide rail 5, and can side-to-side movement on Y-axis guide rail 5, Y-axis feed screw nut 14 is fixed on Y-axis slide block 11, and be connected with Y-axis servomotor 3 by Y-axis screw mandrel 12, the rotating drive Y-axis screw mandrel 12 of Y-axis servomotor 3 rotates, and drives Y-axis nut 14 and Y-axis slide block 11 side-to-side movement.
X-axis guide rail 6 is fixedly mounted on Y-axis slide block 11, vertical with Y-axis at horizontal plane, can with Y-axis slide block 11 side-to-side movement.X-axis servomotor 15 is fixedly mounted on X-axis guide rail 6 rear end, X-axis slide block 10 is arranged on X-axis guide rail 6, and can seesaw along X-axis guide rail 6, X-axis nut 22 to be fixed on X-axis slide block 10 and to be connected with X-axis servomotor 15, the rotating drive X-axis screw mandrel 23 of X-axis servomotor 15 rotates, and drives X-axis nut (22) and X-axis slide block 10 to seesaw.
Z axis guide rail 4 is fixedly mounted on X-axis slide block 10, vertical with X-axis at perpendicular, can seesaw with X-axis slide block 10.Z axis servomotor 7 is fixedly mounted on Z axis guide rail 4 upper end, Z axis slide block 16 is arranged on X-axis guide rail 4, and can move up and down along Z axis guide rail 4, Z axis nut 20 to be fixed on Z axis slide block 16 and to be connected with Z axis servomotor 7, the rotating drive Z axis screw mandrel 3 of Z axis servomotor 7 rotates, and drives Z axis nut 20 and Z axis slide block 16 to move up and down.And can simultaneously with X-axis guide rail 6 side-to-side movement.
Cutter conversion motor 17 is fixedly mounted on Z axis slide block 16, tool changement 2 is connected with motor 17 by motor shaft 19, cutter conversion motor 17 rotating band cutter transfer equipment rotates, cutter conversion motor 17 rotates different angles, and different cutters can be made to be in working position bottom.
Gel collection container putting hole 18 on Stage microscope is positioned at Stage microscope front end near operator position, for placing experimenter for collecting the container of object gel piece.Can place as the container such as centrifuge tube or porous plate.
Computer 21 is connected with CCD camera by built-in image pick-up card; Be connected with motion controller by USB interface or parallel port, motion controller is connected with motor driver, and driving mechanism is connected respectively with four servomotors on machine intimate three-dimensional motion machinery device.
Claims (4)
1. an automatic gel device for cutting, is characterized in that: comprise Stage microscope (1), cuts glue cutter (2), CCD digital camera (8), gel imaging instrument shell (9), sliding support structure, computer (21); Stage microscope (1) is provided with to bottom in described gel imaging instrument shell (9), cutting glue cutter (2) arranges in sliding support structure, cut glue cutter (2) by the drive of sliding support structure to move in gel imaging instrument shell (9), CCD digital camera (8) is arranged in gel imaging instrument shell (9) top and gathers sampling pattern, and CCD digital camera (8) is connected with computer (21).
2. automatic gel device for cutting according to claim 1, is characterized in that: described sliding support structure comprises Z axis screw mandrel (3), Z axis lead rail axis (4), Y-axis guide rail (5), X-axis guide rail (6), Z axis servomotor (7), X-axis slide block (10), Y-axis slide block (11), Y-axis screw mandrel (12), Y-axis servomotor (13), X-axis servomotor (15), Z axis slide block (16), X-axis screw mandrel (23);
Described Y-axis guide rail (5) and Y-axis servomotor (13) are fixedly mounted in shell (9), it is upper and along Y-axis guide rail (5) side-to-side movement that Y-axis slide block (11) is arranged in Y-axis guide rail (5), Y-axis feed screw nut (14) is fixed on Y-axis slide block (11), is connected with Y-axis servomotor (3) by Y-axis screw mandrel (12); The rotating drive Y-axis screw mandrel (12) of Y-axis servomotor (3) rotates and drives Y-axis slide block (11) side-to-side movement;
It is upper vertical with Y-axis guide rail (5) that described X-axis guide rail (6) is fixed on Y-axis slide block (11), can with Y-axis slide block (11) side-to-side movement; X-axis servomotor (15) is fixed on X-axis guide rail (6) rear end, X-axis slide block (10) is arranged on X-axis guide rail (6), and seesaw along X-axis guide rail (6), X-axis servomotor (15) drives X-axis screw mandrel (23) rotate and drive X-axis slide block (10) to seesaw;
Described Z axis guide rail (4) is fixed on X-axis slide block (10), vertical with X guide rail (6) axle, can seesaw with X-axis slide block (10);
Z axis servomotor (7) is fixedly mounted on Z axis guide rail (4) upper end, and Z axis slide block (16) is arranged in X-axis guide rail (4) and goes up and move up and down along Z axis guide rail (4); The driving Z axis screw mandrel (3) of Z axis servomotor (7) rotates and drives Z axis slide block (16) to move up and down and can simultaneously with X-axis guide rail (6) side-to-side movement.
3. automatic gel device for cutting according to claim 2, it is characterized in that: also comprise cutter conversion motor (17), described cutter conversion motor (17) is arranged on Z axis slide block (16), cut glue cutter (2) and cutter conversion motor (17), cutter conversion motor (17) rotates drive and cuts glue cutter (2) rotation.
4. automatic gel device for cutting according to claim 1, is characterized in that: Stage microscope (1) is provided with gel collection container putting hole (18), for placing experimenter for collecting the container of object gel piece.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201420667804.2U CN204325332U (en) | 2014-11-11 | 2014-11-11 | A kind of gel device for cutting automatically |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201420667804.2U CN204325332U (en) | 2014-11-11 | 2014-11-11 | A kind of gel device for cutting automatically |
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CN204325332U true CN204325332U (en) | 2015-05-13 |
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CN201420667804.2U Expired - Fee Related CN204325332U (en) | 2014-11-11 | 2014-11-11 | A kind of gel device for cutting automatically |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104960006A (en) * | 2015-06-04 | 2015-10-07 | 上海海洋大学 | Automatic anti-toxin gel cutting machine, imager and gel cutting method of anti-toxin automatic gel cutting machine |
CN109628554A (en) * | 2018-11-16 | 2019-04-16 | 上海爪鸽医药科技有限公司 | A kind of nucleic acid gel extraction automatic method based on image recognition |
CN112432989A (en) * | 2020-10-29 | 2021-03-02 | 北京擎科生物科技有限公司 | Rubber cutting instrument |
CN112440303A (en) * | 2020-10-29 | 2021-03-05 | 北京擎科生物科技有限公司 | Rubber cutting head driving mechanism |
-
2014
- 2014-11-11 CN CN201420667804.2U patent/CN204325332U/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104960006A (en) * | 2015-06-04 | 2015-10-07 | 上海海洋大学 | Automatic anti-toxin gel cutting machine, imager and gel cutting method of anti-toxin automatic gel cutting machine |
CN109628554A (en) * | 2018-11-16 | 2019-04-16 | 上海爪鸽医药科技有限公司 | A kind of nucleic acid gel extraction automatic method based on image recognition |
CN112432989A (en) * | 2020-10-29 | 2021-03-02 | 北京擎科生物科技有限公司 | Rubber cutting instrument |
CN112440303A (en) * | 2020-10-29 | 2021-03-05 | 北京擎科生物科技有限公司 | Rubber cutting head driving mechanism |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150513 Termination date: 20201111 |