CN204251615U - Bio-reactor - Google Patents

Bio-reactor Download PDF

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Publication number
CN204251615U
CN204251615U CN201420684713.XU CN201420684713U CN204251615U CN 204251615 U CN204251615 U CN 204251615U CN 201420684713 U CN201420684713 U CN 201420684713U CN 204251615 U CN204251615 U CN 204251615U
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China
Prior art keywords
cover
pipe
gauze
run
tank body
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Application number
CN201420684713.XU
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Chinese (zh)
Inventor
卢文玉
尹静
张传波
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Tianjin University
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Tianjin University
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Abstract

The utility model discloses a kind of bio-reactor, comprise tank body 1, cover 2, cooling base 3 is provided with in the bottom of tank body, cooling base is provided with entrance of cooling water 4 and cooling water outlet 5, the top of inlet pipe 6 is run through and is arranged on cover, the lower end of inlet pipe is connected with gas pipe 16, the top of motor driving shaft 7 is run through and is arranged on cover, the middle and lower part of motor driving shaft is provided with stirring rake 8, the top of mixing baffle 10 is run through and is arranged on cover, cover is provided with opening for feed 12 and vapor pipe 14, the surface of the middle and lower part of mixing baffle is provided with gauze 9, the surface of stirring rake is provided with gauze 9, be connected with around pipe rod 13 at the upper surface of cover, vapor pipe is connected with flexible pipe 15, Ruan Guan Chan is arranged around around pipe rod.The utility model can reduce the evaporation of fermented liquid, reduces viscosity, reduces energy consumption, improves dissolved oxygen; Gauze can reduce shearing force, and fixing bacterium, improves leavened prod output.

Description

Bio-reactor
Technical field
The utility model relates to a kind of bio-reactor.
Background technology
Pleocidin is a kind of macrolide antibiotics produced through aerobic fermentation by thorn saccharopolyspora strain.Pleocidin effectively can prevent and treat the multiple lepidoptera pest such as small cabbage moth, beet armyworm, toxicity (ACS symposiumseries.Discovery be there is no to Mammals, birds etc. simultaneously, isolation, and structure elucidation of a family of structurallyunique, fermentation-derived tetracyclic macrolides.1992).It is considered to the most effective biotic pesticide after Avrmectin, becomes the focus of novel biopesticide research and development.
Thorn saccharopolyspora strain is in liquid fermenting process, and mycelium can form mycelium pellet, after fermentation the phase, and its fermented liquid thickness, needs the rotating speed that fermentor tank provides higher, to maintain fermented liquid dissolved oxygen level.Common fermentation tank improves rotating speed, shearing force in fermentor tank is increased, is smashed by thorn saccharopolyspora strain mycelium, and then pleocidin fermentation yield is significantly reduced.
Utility model content
The purpose of this utility model be to provide a kind of can reduce that shearing force and fermented liquid evaporate, can production cost be reduced, improve the bio-reactor of product production.
The technical solution of the utility model is summarized as follows:
A kind of bio-reactor, comprise tank body 1, cover 2, cooling base 3 is provided with in the bottom of tank body, cooling base is provided with entrance of cooling water 4 and cooling water outlet 5, the top of inlet pipe 6 is run through and is arranged on cover, the lower end of inlet pipe is connected with gas pipe 16, the top of motor driving shaft 7 is run through and is arranged on cover, the middle and lower part of motor driving shaft is provided with stirring rake 8, the top of mixing baffle 10 is run through and is arranged on cover, cover is provided with opening for feed 12 and vapor pipe 14, the surface of the middle and lower part of mixing baffle is provided with gauze 9, the surface of stirring rake is provided with gauze 9, be connected with around pipe rod 13 at the upper surface of cover, vapor pipe is connected with flexible pipe 15, Ruan Guan Chan is arranged around around pipe rod.
Gauze is preferably 6-9 layer.
When the volume of tank body is 5L, the length of flexible pipe is 6-10m.
The advantage of bio-reactor of the present utility model:
The setting of flexible pipe, can reduce the evaporation of fermented liquid, reduces fermented liquid viscosity, reduces energy consumption, improves dissolved oxygen; By arranging gauze on stirring rake and mixing baffle, reduce shearing force, improve leavened prod output, the gauze be simultaneously wound around can play the effect of fixing bacterium, improves leavened prod output.
Accompanying drawing explanation
Fig. 1 is the utility model bioreactor construction schematic diagram.
Embodiment
Below in conjunction with accompanying drawing, the utility model is described in further detail:
A kind of bio-reactor, comprise tank body 1, cover 2, cooling base 3 is provided with in the bottom of tank body, cooling base is provided with entrance of cooling water 4 and cooling water outlet 5, the top of inlet pipe 6 is run through and is arranged on cover, the lower end of inlet pipe is connected with gas pipe 16, the top of motor driving shaft 7 is run through and is arranged on cover, the middle and lower part of motor driving shaft is provided with stirring rake 8, the top of mixing baffle 10 is run through and is arranged on cover, cover is provided with opening for feed 12 and vapor pipe 14, the surface of the middle and lower part of mixing baffle is provided with gauze 9, the surface of stirring rake is provided with gauze 9, be connected with around pipe rod 13 at the upper surface of cover, vapor pipe is connected with flexible pipe 15, Ruan Guan Chan is arranged around around pipe rod.
Gauze is preferably 6-9 layer.
Stirring rake is connected with external motor by motor driving shaft.
Flexible pipe can select rubber hose or plastic hose.The length of flexible pipe is determined according to the volume of tank body 1, and when the volume of tank body 1 is 5L, the length of flexible pipe selects 6-10m length to be advisable.When the volume of tank body 1 is less than 5L, the length of flexible pipe suitably can be selected and be less than 6m's.
The gauze that mixing baffle is arranged, can adopt the method for winding to arrange.
Can also arrange dissolved oxygen, PH, pressure, temperature electrode sensor in tank body 1, sensor is connected with master control system by wire.
Soft tube winding is on pipe rod, the gas that fermented liquid evaporation produces cools at flexible pipe, turn back to again in tank body, fermented liquid evaporation can be reduced, reduce energy consumption, improve fermented liquid output, mixing baffle and stirring rake are wrapped with gauze, significantly can reduce mixing baffle and stirring rake to the shearing force of cultivated thalline, improve fermentation production rate.
Bio-reactor is utilized to ferment to thorn saccharopolyspora strain, when the volume of tank body is 5L, when the length of flexible pipe is 6m, vaporator rate is reduced to about 4mL/h by 10mL/h, (10mL/h, referring to structural similitude of the present utility model, just do not add flexible pipe, but around vapor pipe, refrigerating unit is installed) viscosity of fermented liquid obviously declines, consumption and the wear rate of glucose increase all to some extent, thalli growth is vigorous, fermentation ends, the output increased of pleocidin 20%.

Claims (3)

1. a bio-reactor, comprise tank body (1), cover (2), cooling base (3) is provided with in the bottom of tank body, cooling base is provided with entrance of cooling water (4) and cooling water outlet (5), the top of inlet pipe (6) is run through and is arranged on cover, the lower end of inlet pipe is connected with gas pipe (16), the top of motor driving shaft (7) is run through and is arranged on cover, the middle and lower part of motor driving shaft is provided with stirring rake (8), the top of mixing baffle (10) is run through and is arranged on cover, cover is provided with opening for feed (12) and vapor pipe (14), it is characterized in that the surface of the middle and lower part of mixing baffle is provided with gauze (9), gauze (9) is provided with on the surface of stirring rake, be connected with around pipe rod (13) at the upper surface of cover, vapor pipe is connected with flexible pipe (15), soft tube winding is arranged around pipe rod.
2. a kind of bio-reactor according to claim 1, is characterized in that described gauze is 6-9 layer.
3. a kind of bio-reactor according to claim 1, when the volume that it is characterized in that described tank body is 5L, the length of flexible pipe is 6-10m.
CN201420684713.XU 2014-11-14 2014-11-14 Bio-reactor Active CN204251615U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201420684713.XU CN204251615U (en) 2014-11-14 2014-11-14 Bio-reactor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201420684713.XU CN204251615U (en) 2014-11-14 2014-11-14 Bio-reactor

Publications (1)

Publication Number Publication Date
CN204251615U true CN204251615U (en) 2015-04-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201420684713.XU Active CN204251615U (en) 2014-11-14 2014-11-14 Bio-reactor

Country Status (1)

Country Link
CN (1) CN204251615U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104342361A (en) * 2014-11-14 2015-02-11 天津大学 Biological reactor
CN108192819A (en) * 2018-03-06 2018-06-22 寿光新润科技中介服务有限公司 A kind of biofermentation reaction kettle of the anti-compaction adjusted equipped with temperature

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104342361A (en) * 2014-11-14 2015-02-11 天津大学 Biological reactor
CN108192819A (en) * 2018-03-06 2018-06-22 寿光新润科技中介服务有限公司 A kind of biofermentation reaction kettle of the anti-compaction adjusted equipped with temperature

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