CN204154722U - A kind of intelligent immunochromatography and spectral analysis integrated apparatus - Google Patents

A kind of intelligent immunochromatography and spectral analysis integrated apparatus Download PDF

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Publication number
CN204154722U
CN204154722U CN201420363763.8U CN201420363763U CN204154722U CN 204154722 U CN204154722 U CN 204154722U CN 201420363763 U CN201420363763 U CN 201420363763U CN 204154722 U CN204154722 U CN 204154722U
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module
integrated apparatus
spectral analysis
touch screen
liquid crystal
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CN201420363763.8U
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Inventor
姚世平
刘光中
姚洪涛
马彪
周轶
韩啸
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Medi Weidun (beijing) Technology Development Co Ltd
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Beijing Biochem Huaye Technology Development Co Ltd
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Abstract

The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, for the examination of some poisonous and harmful substances in food and medicine cosmetics and potable water.Comprise housing, human-computer interaction module, light-source system, image capture module, Data Analysis Services module and data upload module, wherein human-computer interaction module mainly comprises liquid crystal display touch screen and control circuit, housing is provided with liquid crystal display touch screen and power switch key, pattern detection window is provided with at housing right flank, after housing, be provided with outlet, USB and network outlet, image capture module mainly comprises planar array type CCD camera.The bulky problem of instrument is solved owing to adopting planar array type CCD camera, coordinate upper computer software can realize the precise calibration of test card in addition, solve the problem of testing result poor stability, image acquisition, storage and reproduction can also be carried out to test zone in addition.

Description

A kind of intelligent immunochromatography and spectral analysis integrated apparatus
Technical field
The utility model relates to a kind of intelligent immunochromatography and spectral analysis integrated apparatus, for the examination of some poisonous and harmful substances in food and medicine cosmetics and potable water.
Background technology
The method that quantitatively instrument mainly adopts at present has optical fiber scanning method and linear array CCD scanning method.
Optical fiber scanning method is moved by driven by motor test strips, and Fibre Optical Sensor is scanned from the background area of test strips to p-wire.The incident light sent by light emitting diode is radiated on test paper test section, and reflected light is sent to photodetector via reception optical fiber and converts photosignal output to, and electric signal size is corresponding with the size of test section reflective light intensity.The method needs to drive Fibre Optical Sensor to scan by mechanical scanner, causes instrument volume heavy greatly; And when low concentration, because intensity of reflected light change is very faint, measurement result poor stability can be caused.
Linear array CCD scanning method to some extent solves that instrument volume in optical fiber scanning method is large, the problem of Measurement sensibility difference, but because linear CCD sensor can only gather the photosignal on a certain bar line, so the decline of measurement result stability still can be caused, and measurement result can only show reproduction in the form of data, with the display of the form of picture and can not reappear.
In addition, food and medicine cosmetics and potable water poisonous and harmful substance quantitatively detect at present mainly through two kinds of immunochromatographic methods and chemical percolation two kinds of methods, the project that these two kinds of detection methods detect is Uncrossed each other, but also do not have pick-up unit to concentrate in same set of equipment by above-mentioned two kinds of methods simultaneously, cause the test item of checkout equipment incomplete like this, can not carry out complete detection fast, communication mode is also confined to USB flash disk, network and bluetooth simultaneously simultaneously.
Utility model content
Large in order to overcome existing instrument volume, measurement result degree of stability difference and measurement result can not with graphic form display and the problems of reappearing, the utility model provides a kind of intelligent immunochromatographiassays assays device, planar array type CCD camera is adopted to solve the bulky problem of gold mark detector, coordinate upper computer software the utility model can realize the precise calibration of test card in addition, solve the problem of testing result poor stability, planar array type CCD camera due to what adopt in the utility model, so image acquisition can be carried out to test zone, store and reappear.
In order to the defect that the test item overcoming existing instrument is incomplete, the utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus and analytical approach thereof, its test card comprises colloidal-gold detecting-card and physical and chemical testing card, colloidal gold test card is by detecting by immunochromatographic method, physical and chemical testing cartoon is crossed chemical percolation and is detected, data upload module adds 3G communication module in addition, makes that detection is convenient can be detected immediately namely.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, comprise housing, human-computer interaction module, light-source system, image capture module, Data Analysis Services module and data upload module, human-computer interaction module mainly comprises liquid crystal display touch screen and control circuit, light-source system mainly comprises LED and can provide visible ray, housing is provided with liquid crystal display touch screen, outlet is provided with at housing left surface, pattern detection window is provided with at housing right flank, draw-in groove and power switch key, USB and network outlet is provided with after housing, image capture module mainly comprises planar array type CCD camera, this device also comprises test card in addition, test card is divided into colloidal gold test card and physical and chemical testing card also can insert pattern detection window to top, data upload module comprises bluetooth communication, usb communication module, network interface communication module and 3G communication module.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, planar array type CCD camera is arranged in a square formation by a lot of photosensitive area and connects into a device.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein human-computer interaction module can control power-supply system, image capture module, Data Analysis Services module and data upload module work by liquid crystal display touch screen and control circuit.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein liquid crystal display touch screen is LCDs, is also capacitive touch screen.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein liquid crystal display touch screen is provided with measurement, Reagent management, historical record and Operation system setting four buttons, can enter test item respectively select interface, Reagent management interface, historical record to check interface and Operation system setting interface operation by described measurement, Reagent management, historical record and Operation system setting four buttons.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein the weight of this device is 0.8kg, be of a size of 220mm × 110mm × 75mm, power is 4.8W, operating temperature range is-10 DEG C of < T < 45 DEG C, optimum operation temperature is 25 DEG C, and the coefficient of variation is CV≤3%.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein colloidal gold test card is detected by immunochromatographic method, and physical and chemical testing card is detected by chemical percolation.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein device can detect total aflatoxin content, aflatoxin B1, Aflatoxins M1, zearalenone, vomitoxin, chloromycetin, sulfamido many residual, fluoquinolone, clenobuterol hydrochloride, salbutamol, Ractopamine, melamine, papaverine, malachite green and Tetracyclines by colloidal gold test card.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein device can detect nitrite, heavy metal Hg, sulphuric dioxide, chlorine residue, edible oil acid value, edible oil peroxide value and hydrogen peroxide by physical and chemical testing card.
The analytical approach of a kind of intelligent immunochromatography and spectral analysis integrated apparatus disclosed in the utility model, step is as follows:
The first step: test card is calibrated, test card calibration needs to carry out in conjunction with upper computer software, and concrete parameter is decided by reagent itself;
Second step: import calibration curve, the calibration curve generated in host computer is imported to a kind of intelligent immunochromatographiassays assays device by USB;
3rd step: operator, by the described liquid crystal display touch screen of described human-computer interaction module, selects to need the project of detection and determines to detect;
4th step: after image capture module receives sense command, can pass through planar array type CCD camera collection test card gray scale pictures;
5th step: Data Analysis Services module calculates corresponding testing result according to calibration curve and the photo collected, and be presented on liquid crystal display touch screen detect data;
6th step: project has been detected rear operator and can have been uploaded detection data by data upload model choice bluetooth communication, usb communication module and network interface communication module as required.
Beneficial effect
A kind of intelligent immunochromatography disclosed in the utility model and spectral analysis integrated apparatus and analytical approach thereof, adopt planar array type CCD camera, volume is little, image acquisition, storage and reproduction can be carried out to test zone, the data collected like this are more complete, so the precise calibration of test card can be realized, testing result good stability.Its test card comprises colloidal-gold detecting-card and physical and chemical testing card in addition, so namely this device can pass through immunochromatographyassay assay, also can be detected by chemical percolation, test item is more comprehensive, data upload module adds 3G communication module, makes that detection is convenient can be detected immediately namely.
Accompanying drawing explanation
Fig. 1 is the stereographic map of a kind of intelligent immunochromatography and spectral analysis integrated apparatus and analytical approach thereof.
Fig. 2 is the right view of a kind of intelligent immunochromatography and spectral analysis integrated apparatus and analytical approach thereof.
Fig. 3 is the rear view of a kind of intelligent immunochromatography and spectral analysis integrated apparatus and analytical approach thereof.
Fig. 4 is the principle of work schematic diagram of a kind of intelligent immunochromatography and spectral analysis integrated apparatus and analytical approach thereof.
Fig. 5 is the analytical procedure schematic diagram of a kind of intelligent immunochromatography and spectral analysis integrated apparatus.
Embodiment
Below in conjunction with the drawings and specific embodiments, the utility model is described in further detail, but not as to restriction of the present utility model.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, comprise housing (01), human-computer interaction module (08), light-source system (09), image capture module (10), Data Analysis Services module (11) and data upload module (12), human-computer interaction module (08) mainly comprises liquid crystal display touch screen (02) and control circuit (not shown), light-source system (09) mainly comprises LED and can provide visible ray, housing (01) is provided with liquid crystal display touch screen (02), outlet (05) is provided with at housing (01) left surface, pattern detection window (04) is provided with at housing (01) right flank, draw-in groove (14) and power switch key (03), USB (06) and network outlet (07) is provided with below at housing (01), image capture module (10) mainly comprises planar array type CCD camera (not shown), this device also comprises test card (13) in addition, test card (13) is divided into colloidal gold test card and physical and chemical testing card also can insert pattern detection window (04) to top, data upload module (12) comprises bluetooth communication, usb communication module, network interface communication module and 3G communication module.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein image capture module (10) adopts planar array type CCD camera, and CCD functionally can be divided into line array CCD and the large class of area array CCD two.CCD internal electrode is divided into array by line array CCD usually, and often group is called a phase, and applies same time clock.The required number of phases is determined by CCD chip inner structure, and the different CCD of structure can meet the request for utilization of different occasion.Line array CCD have single raceway groove and double channel point, its photosensitive area is mos capacitance or photodiode structure, and production technology is relatively simple.It is made up of photosensitive area array and shift register sweep circuit, and feature is that process information speed is fast, and peripheral circuit is simple, easily realize controlling in real time, but obtaining information amount is little, can not process complicated image.The structure of area array CCD is more complex, and it is arranged in a square formation by a lot of photosensitive area, and connects into a device with certain form, and obtaining information amount is large, can process complicated image.
Fig. 4 is the principle of work schematic diagram of a kind of intelligent immunochromatography and spectral analysis integrated apparatus.Light-source system (09), image capture module (10), Data Analysis Services module (11) and data upload module (12) are controlled by human-computer interaction module (08) as we can see from the figure, more precisely, human-computer interaction module (08) can pass through liquid crystal display touch screen (02) and the work of control circuit control light-source system (09), image capture module (10), Data Analysis Services module (11) and data upload module (12).
As shown in Figure 1, the utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein liquid crystal display touch screen (02) is LCDs, is also capacitive touch screen.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein liquid crystal display touch screen (02) is provided with measurement, Reagent management, historical record and Operation system setting four buttons, can enter test item respectively select interface, Reagent management interface, historical record to check interface and Operation system setting interface operation by described measurement, Reagent management, historical record and Operation system setting four buttons.Test item selects interface to have " returning " " refreshing " " to determine " three buttons, corresponding test item can be selected to detect by these three buttons, when after selected detailed programs, press " determination " key, interface will jump to measures interface, " return " " uploading " several button in measurement interface " measurements ", use and corresponding operating can be completed by these three buttons.In Reagent management interface, devise " returning " and " to stop using " and " importing " three buttons can be imported calibration curve by these three buttons and delete.To check in the page can check testing result in the past by " page up " " lower one page " two buttons at historical record, and can be operated testing result by buttons such as " uploading " " deletions ".At Operation system setting interface, the parameter such as system time, automatic shutdown time can be set.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein the weight of this device is 0.8kg, be of a size of 220mm × 110mm × 75mm, power is 4.8W, operating temperature range is-10 DEG C of < T < 45 DEG C, optimum operation temperature is 25 DEG C, and the coefficient of variation is CV≤3%.
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein colloidal gold test card is detected by immunochromatographic method, and physical and chemical testing card is detected by chemical percolation.
The invention also discloses the analytical approach of a kind of intelligent immunochromatography and spectral analysis integrated apparatus, as shown in Figure 5, step is as follows:
The first step: test card is calibrated, test card calibration needs to carry out in conjunction with upper computer software, and concrete parameter is decided by reagent itself;
Second step: import calibration curve, the calibration curve generated in host computer is imported to a kind of intelligent immunochromatographiassays assays device by USB;
3rd step: operator, by the described liquid crystal display touch screen of described human-computer interaction module, selects to need the project of detection and determines to detect;
4th step: after image capture module receives sense command, can pass through planar array type CCD camera collection test card gray scale pictures;
5th step: Data Analysis Services module calculates corresponding testing result according to calibration curve and the photo collected, and be presented on liquid crystal display touch screen detect data;
6th step: project has been detected rear operator and can have been uploaded detection data by data upload model choice bluetooth communication, usb communication module and network interface communication module as required.
Embodiment one
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein device can detect total aflatoxin content, aflatoxin B1, Aflatoxins M1, zearalenone, vomitoxin, chloromycetin, sulfamido many residual, fluoquinolone, clenobuterol hydrochloride, salbutamol, Ractopamine, melamine, papaverine, malachite green and Tetracyclines by colloidal gold test card.
Describe in detail for Ractopamine product below, test card (13) adds testing sample, wait for 10 minutes, test card (13) is inserted in the groove of pattern detection window (04) to top in well mode inwards, click the test button on liquid crystal display touch screen (02), this intelligent immunochromatographiassays assays device detects after 8 seconds reciprocal, and demonstrates testing result.Qualitative product can demonstrate the result of " feminine gender ", " positive ", " suspicious ", and basis weight products can show detection sample concentration value.
The minimum detectability of this device is gray scale 5, and naked eyes are judged as wireless, and when namely naked eyes judge wireless, gold mark instrument gray scale result is less than 5.This intelligent immunochromatographiassays assays device Supreme Procuratorate rising limit is gray scale 1200, and when namely detection line is aterrimus, gold mark instrument gray scale result is more than 1200.For Ractopamine product, when detecting negative, product develops the color the most deeply, and gray scale is about 300, and when detecting 20ppb sample, gray scale is within 5.
Utilize the repeatability of Ractopamine Product checking gold mark instrument, same bar (detecting 5ppb sample), repeatedly detect 10 times, result is as follows:
Table one
As can be seen from table one, the repeatability of a kind of intelligent immunochromatography and spectral analysis integrated apparatus disclosed in the utility model and good stability.
Embodiment two
The utility model discloses a kind of intelligent immunochromatography and spectral analysis integrated apparatus, wherein device can detect nitrite, heavy metal Hg, sulphuric dioxide, chlorine residue, edible oil acid value, edible oil peroxide value and hydrogen peroxide by physical and chemical testing card.
Be described in detail for nitrite below, draw 4ul to detect sample or pick a small amount of sample drop that detects on the detection color lump of test card with glass bar, wait for about 3 minutes, test card (13) is inserted in the groove of pattern detection window (04) to top in well mode inwards, the test button at clicking operation interface, detector detects after 8 seconds reciprocal, click the test button on liquid crystal display touch screen (02), this intelligent immunochromatographiassays assays device detects after 8 seconds reciprocal, and demonstrates testing result.Qualitative product can demonstrate the result of " feminine gender ", " positive ", " suspicious ", and basis weight products can show detection sample concentration value.
The colored intensity of this device to variable concentrations has different tonal ranges, and negative gray scale is about 100, and detection sensitivity is 0.5mg/kg, and gray scale is about 150, and highest detection limit 40mg/kg gray scale is about 630.
Utilize the repeatability of this device of nitrite Product checking, same bar (detecting 0.5mg/kg), repeatedly detect 10 times, result is as follows:
Table two
As can be seen from table two, the repeatability of a kind of intelligent immunochromatography and spectral analysis integrated apparatus disclosed in the utility model and good stability.

Claims (6)

1. an intelligent immunochromatography and spectral analysis integrated apparatus, comprise housing, human-computer interaction module, light-source system, image capture module, Data Analysis Services module and data upload module, described human-computer interaction module mainly comprises liquid crystal display touch screen and control circuit, described light-source system mainly comprises LED and can provide visible ray, be provided with liquid crystal display touch screen on the housing, outlet is provided with at described housing left surface, pattern detection window is provided with at described housing right flank, draw-in groove and power switch key, USB and network outlet is provided with after described housing, described image capture module mainly comprises planar array type CCD camera, it is characterized in that: described device also comprises test card, described test card is divided into colloidal gold test card and physical and chemical testing card also can insert described pattern detection window to top, described data upload module comprises bluetooth communication, usb communication module, network interface communication module and 3G communication module.
2. the intelligent immunochromatography of one according to claim 1 and spectral analysis integrated apparatus, is characterized in that: described planar array type CCD camera is arranged in a square formation by a lot of photosensitive area and connects into a device.
3. the intelligent immunochromatography of one according to claim 1 and spectral analysis integrated apparatus, is characterized in that: described human-computer interaction module can control described light-source system, described image capture module, described Data Analysis Services module and described data upload module work by described liquid crystal display touch screen and described control circuit.
4. the intelligent immunochromatography of one according to claim 1 and spectral analysis integrated apparatus, it is characterized in that: described liquid crystal display touch screen is LCDs, is also capacitive touch screen.
5. the intelligent immunochromatography of one according to claim 1 and spectral analysis integrated apparatus, it is characterized in that: described liquid crystal display touch screen is provided with measurement, Reagent management, historical record and Operation system setting four buttons, test item can be entered respectively by described measurement, Reagent management, historical record and Operation system setting four buttons and select interface, Reagent management interface, historical record to check interface and Operation system setting interface operation.
6. the intelligent immunochromatography of one according to claim 1 and spectral analysis integrated apparatus, it is characterized in that: the weight of described device is 0.8kg, be of a size of 220mm × 110mm × 75mm, power is 4.8W, operating temperature range is-10 DEG C of < T < 45 DEG C, optimum operation temperature is 25 DEG C, and the coefficient of variation is CV≤3%.
CN201420363763.8U 2014-07-03 2014-07-03 A kind of intelligent immunochromatography and spectral analysis integrated apparatus Expired - Lifetime CN204154722U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105277680A (en) * 2014-07-03 2016-01-27 北京倍肯华业科技发展有限公司 Intelligentized immunochromatography and spectral analysis integrated device and analysis method therefor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105277680A (en) * 2014-07-03 2016-01-27 北京倍肯华业科技发展有限公司 Intelligentized immunochromatography and spectral analysis integrated device and analysis method therefor

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Address after: Room 201, No. 1 Xingchang Road, Changping District, Beijing 102200

Patentee after: Medi Weidun (Beijing) Technology Development Co., Ltd.

Address before: Room 201, No. 1 Xingchang Road, Changping District, Beijing 102200

Patentee before: BEIJING BIOCHEM HUAYE TECHNOLOGY DEVELOPMENT CO., LTD.