CN204086296U - Simple and easy microfluid flow rate measuring device - Google Patents
Simple and easy microfluid flow rate measuring device Download PDFInfo
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- CN204086296U CN204086296U CN201420612125.5U CN201420612125U CN204086296U CN 204086296 U CN204086296 U CN 204086296U CN 201420612125 U CN201420612125 U CN 201420612125U CN 204086296 U CN204086296 U CN 204086296U
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Abstract
The utility model relates to a kind of simple and easy microfluid flow rate measuring device, and described measurement mechanism to be tested the speed passage by rate of flow of fluid, gas inject passage, the micro flow chip that bubble formation passage is formed and bubble detected image harvester composition; Bubble formation passage end is closed, the other end and the rate of flow of fluid passage that tests the speed is interconnected, one end, bubble injection channel is closed, the blind end of bubble injection channel and the blind end of bubble formation passage positioned opposite, and be provided with breathing waterproof film between two blind ends, the external computing machine of bubble detected image harvester.The utility model measurement mechanism possesses beneficial effect: fluid-velocity survey mode is simple, and fluid can not blow back into gas channel, and namely gas isolate fluid after experiment, is the direct measurement of fluid flow rate.The utility model is reasonable in design, and structure is simple, high integration, and convection cell can not cause any pollution, and being applicable to needs nondestructive measurement microfluid fluid-velocity survey to test in micro-fluidic chip.
Description
Technical field
The utility model relates to a kind of simple and easy microfluid flow rate measuring device.Belong to fluid measurement technology.
Background technology
The beginning of the nineties in last century micro-total analysis system put forward, and can realize the chip system that miniature biochemical is analyzed.Micro-total analysis system has the distinguishing features such as detection speed is fast, style consumption is few, flux is high.Dimethyl silicone polymer (PDMS), as a kind of polymkeric substance having the fabulous transparency, low cytotoxicity, gas penetration potential, has been widely used in biochemical micro-total analysis system with the micro-fluidic chip that PDMS and slide are base material.In micro flow chip system, working fluid is main bearing medium, carries out actual flow velocity measurement, and regulate and control according to actual needs microfluid, has been one of biochemical analysis checkout procedure core parameter, is also one of micro-fluidic core technology.The flow velocity of microfluid is less, cannot accurately measure its flow velocity by the fluid velocity measuring method of routine.
Have at rate of flow of fluid measurement mechanism at present: ultrasound speed variator, as (patent CN201310001989), photoelectricity voltage fluctuation signal speed measuring device, as (patent CN200910103372), or spike particulate imaging speed measuring device, as devices such as (patents 201010163676) measures the flow velocity of microfluid.But mode brings many problems above, such as introduce other probe materials, cannot Measurement accuracy and processed complex etc.Common fluids fluid-velocity survey can solve contaminant problem by reducing precision, or introducing trace impurity improves precision.But, ensure that the microfluid fluid-velocity survey of precision and degree of purity is but controling parameters necessary in micro-total analysis chip system simultaneously.Meanwhile, introducing impurity is that major part experiment does not allow occurrence, introduces impurity or measuring error easily causes the failure of an experiment in degree of purity and the higher experiment of accuracy requirement.Therefore, microfluid fluid-velocity survey problem has become the long-term major obstacle hindering micro-total analysis system development.
Summary of the invention
The purpose of this utility model is to overcome the defect that above-mentioned prior art exists, provide a kind of structure simply, the simple and easy microfluid flow rate measuring device of safety and sanitation again.
To achieve these goals, the technical solution of the utility model:
Simple and easy microfluid flow rate measuring device, described measurement mechanism to be tested the speed passage by rate of flow of fluid, gas inject passage, the micro flow chip that bubble formation passage is formed and bubble detected image harvester composition; Bubble formation passage end is closed, the other end and the rate of flow of fluid passage that tests the speed is interconnected, one end, bubble injection channel is closed, the blind end of bubble injection channel and the blind end of bubble formation passage positioned opposite, and be provided with breathing waterproof film between two blind ends, the external computing machine of bubble detected image harvester.
Described air permeable waterproof film thickness is 1 μm-1000 μm.
The described rate of flow of fluid passage that tests the speed adopts transparent watertight material.
Rate of flow of fluid tests the speed passage, and the width of gas inject passage and bubble formation passage is 10 μm-1000 μm.
Owing to have employed above technical scheme, the microfluid flow rate measuring device that the utility model provides possesses following beneficial effect:
1) the utility model only needs three passages just can complete fluid-velocity survey chip, and apparatus structure is simple.
2) in spike bubble injection process owing to adopting special breathing waterproof film to intercept gas inject raceway groove and bubble formation raceway groove, therefore there will not be liquid to flow back to the phenomenon of gas inject raceway groove.
3) because gas is not direct and fluid-velocity survey passage is come round, therefore can not form gas column on flow velocity tests the speed raceway groove affects fluid-velocity survey.
4) probe material of fluid-velocity survey adopts the gas do not reacted with fluid to be measured, and is discharged by breathing waterproof film after having tested the speed, therefore on the fluid in microchannel without impact, do not introduce any impurity, safety and sanitation.
5) rate of flow of fluid measurement has been come by spike bubble, and be therefore the direct measurement of the flow velocity of convection cell, measuring accuracy is high.
The utility model is reasonable in design, and structure is simple, high integration, and convection cell can not cause any pollution, and being applicable to needs nondestructive measurement microfluid fluid-velocity survey to test in micro-fluidic chip.
Accompanying drawing explanation
Fig. 1 is the structural representation of the utility model generator.
Fig. 2 is the vertical view of Fig. 1 chips 2.
Embodiment
Below in conjunction with the using method of accompanying drawing and device, the utility model will be further described.
See accompanying drawing
Simple and easy microfluid flow rate measuring device, described measurement mechanism to be tested the speed passage 23 by rate of flow of fluid, gas inject passage 21, and the micro flow chip 2 that bubble formation passage 22 is formed and bubble detected image harvester 1 form, described rate of flow of fluid tests the speed passage 23, the width of gas inject passage 21 and bubble formation passage 22 is 10 μm-1000 μm, different width is adopted for different fluids, the described rate of flow of fluid passage 23 that tests the speed adopts transparent watertight material, the end of described gas inject interface is provided with the air valve for controlling gas flow, described bubble formation passage 22 one end is closed, the other end and the rate of flow of fluid passage 23 that tests the speed is interconnected, one end, bubble injection channel 21 is closed, the blind end of bubble injection channel 21 and the blind end of bubble formation passage 22 positioned opposite, and be provided with breathing waterproof film 31 between two blind ends, described air permeable waterproof film thickness is 1 μm-1000 μm, different thickness is adopted for different gas breathing waterproof films.Described bubble detected image harvester 1 is CCD camera, and this camera is fixed on above fluid-velocity survey passage by support, by the external computing machine of USB interface.
The using method of this device is:
(1) as shown in Figure 1, the chip made is placed on immediately below CCD camera 1 camera lens;
(2) as shown in Figure 2, by microchannel, fluid is injected raceway groove from fluid-infusing port 12;
(3) as shown in Figure 2, after microfluid velocity-stabilization, inject from inert gas inlet 11 gas do not reacted with testing liquid;
(4) control CCD camera with certain position picture taking bubble across frame time t continuously, obtain the trajectory diagram of bubble.
(5) by shooting to bubble track picture pass to host computer and process, utilize the relative position of adjacent picture bubble
with
with the flow velocity V=(S calculating microfluid across frame time t
n-S
n-1) ÷ t.
(6) after having measured, micro flow chip is saved, continue to use when next time measures microfluid of the same race.
Visible, the utility model is applicable to the fluid-velocity survey of various very low volume fluids, such as, flow speed real-time measurement etc. at the control of micro flow chip liquid, complex fluid (blood).Building of microfluid flow rate measuring device of the present utility model is very simply and easily process.In the cost of device, owing to measuring embedding raceway groove not having hardware, greatly save the cost of measurement, for when requiring higher microfluid fluid-velocity survey, this chip can accomplish single use, and the utility model is at the technically real nondestructive measurement accomplished liquid of micro-fluid measurement.
Claims (4)
1. simple and easy microfluid flow rate measuring device, it is characterized in that: described measurement mechanism to be tested the speed passage (23) by rate of flow of fluid, gas inject passage (21), the micro flow chip (2) that bubble formation passage (22) is formed and bubble detected image harvester (1) composition; Bubble formation passage (22) one end is closed, the other end and the rate of flow of fluid passage (23) that tests the speed is interconnected, bubble injection channel (21) one end is closed, the blind end of bubble injection channel (21) and the blind end of bubble formation passage (22) positioned opposite, and be provided with breathing waterproof film (31) between two blind ends, bubble detected image harvester (1) external computing machine.
2. simple and easy microfluid flow rate measuring device as claimed in claim 1, is characterized in that: described air permeable waterproof film thickness is 1 μm-1000 μm.
3. simple and easy microfluid flow rate measuring device as claimed in claim 1, is characterized in that: the described rate of flow of fluid passage (23) that tests the speed adopts transparent watertight material.
4. simple and easy microfluid flow rate measuring device as claimed in claim 1, is characterized in that: rate of flow of fluid tests the speed passage (23), and the width of gas inject passage (21) and bubble formation passage (22) is 10 μm-1000 μm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420612125.5U CN204086296U (en) | 2014-10-22 | 2014-10-22 | Simple and easy microfluid flow rate measuring device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420612125.5U CN204086296U (en) | 2014-10-22 | 2014-10-22 | Simple and easy microfluid flow rate measuring device |
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| Publication Number | Publication Date |
|---|---|
| CN204086296U true CN204086296U (en) | 2015-01-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201420612125.5U Expired - Fee Related CN204086296U (en) | 2014-10-22 | 2014-10-22 | Simple and easy microfluid flow rate measuring device |
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| CN (1) | CN204086296U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104297518A (en) * | 2014-10-22 | 2015-01-21 | 武汉纺织大学 | Simple microfluid flow velocity measuring device |
| CN111443217A (en) * | 2020-04-16 | 2020-07-24 | 国网湖南省电力有限公司 | Device and system for measuring flow velocity of pipeline of water cooling system of phase modulator of transformer substation and application method of device and system |
-
2014
- 2014-10-22 CN CN201420612125.5U patent/CN204086296U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104297518A (en) * | 2014-10-22 | 2015-01-21 | 武汉纺织大学 | Simple microfluid flow velocity measuring device |
| CN104297518B (en) * | 2014-10-22 | 2017-01-25 | 武汉纺织大学 | Simple microfluid flow velocity measuring device |
| CN111443217A (en) * | 2020-04-16 | 2020-07-24 | 国网湖南省电力有限公司 | Device and system for measuring flow velocity of pipeline of water cooling system of phase modulator of transformer substation and application method of device and system |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150107 Termination date: 20161022 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |