CN204028008U - Biochip supplies analysis - Google Patents
Biochip supplies analysis Download PDFInfo
- Publication number
- CN204028008U CN204028008U CN201420437698.9U CN201420437698U CN204028008U CN 204028008 U CN204028008 U CN 204028008U CN 201420437698 U CN201420437698 U CN 201420437698U CN 204028008 U CN204028008 U CN 204028008U
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- Prior art keywords
- ccd camera
- dividing plate
- housing
- supplies analysis
- objective table
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- 238000000018 DNA microarray Methods 0.000 title claims abstract description 30
- 238000004458 analytical method Methods 0.000 title claims abstract description 30
- 230000017525 heat dissipation Effects 0.000 claims abstract description 10
- 230000005540 biological transmission Effects 0.000 claims description 30
- 238000012546 transfer Methods 0.000 claims description 3
- 238000001514 detection method Methods 0.000 description 6
- 230000005281 excited state Effects 0.000 description 6
- 230000005283 ground state Effects 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000000356 contaminant Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 230000003071 parasitic effect Effects 0.000 description 2
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000002795 fluorescence method Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000012113 quantitative test Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
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- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The utility model relates to a kind of biochip supplies analysis, comprising: housing, is provided with dividing plate in housing, and dividing plate is provided with through hole, and the cavity in housing is divided into upper chamber and lower chambers by dividing plate, and the below in housing forward end face is provided with outer door, bogey, bogey is objective table, gearing, gearing is positioned at the bottom of lower chambers, harvester, harvester is CCD camera, CCD camera is fixed on dividing plate, the photosensitive port of CCD camera is positioned at the top of bulkhead through-hole, the object lens of CCD camera are positioned at directly over objective table, shade, shade is two pieces of light shields, two pieces of light shield symmetries are arranged between dividing plate and gearing, control device, control device comprises control circuit board, heat abstractor, described heat abstractor is fan, the housing position corresponding with fan is provided with heat dissipation channel, be provided with color filter above the object lens of CCD camera, the top of color filter is provided with converging lenses.
Description
Technical field
The utility model belongs to biological detection equipment technical field, relates to a kind of detector, especially a kind of biochip supplies analysis.
Background technology
Biological chip testing technology comprises protein-chip detection technique and gene chip detecting technique, obtains applying more and more widely in fields such as scientific research, medical and health, forensic identification, environmental monitorings.
But current biological chip testing technology obtains testing result by detecting fluorescence signal mostly, because the generation of fluorescence be unable to do without exciting light, must cause certainly existing parasitic light in fluorescence, the existence of parasitic light limits the sensitivity of fluorescence method.
But along with the appearance of chemiluminescence, provide a kind of new biological chip testing technology, the free energy discharged in chemical reaction process is utilized to excite intermediate, it is made to get back to ground state from excited state, the photon of energy level such as discharging when intermediate gets back to ground state from excited state, carrying out quantitative test by measuring photon.
Application number is the utility model patent file of 200520039761.4, discloses a kind of biochip supplies analysis, containing following assembly:
Objective table, is positioned under object lens;
One-dimensional precise platform, is positioned at upper strata and installs on dividing plate, by CCD camera;
Shade curtain, is positioned at by objective table;
Dividing plate is installed on upper strata, between chip room and CCD room;
CCD power supply, is positioned at upper strata and installs on dividing plate;
Electric-controlled box, includes central control circuit;
Fan, is positioned at electric control chamber;
Fan power supply, is positioned under object lens, by electric-controlled box;
CCD camera, upper strata is installed on dividing plate;
Fan, is positioned at CCD room;
Object lens, are assemblied in the photosensitive port of CCD camera;
Software, is installed on computing machine.
In technical scheme described in this patent document, the photon that intermediate discharges when getting back to ground state by excited state after object lens directly by the photosensitive Port detecting of CCD camera, and the photon that intermediate discharges when excited state gets back to ground state has scattering, therefore, partial photonic possibly cannot be arrived by the photosensitive Port detecting of CCD camera, thus affects final detection analysis result; In addition, in chemical reaction process, other light signals except the photon that intermediate discharges when excited state gets back to ground state may be produced, if these light signals are arrived by the photosensitive Port detecting of CCD camera, final analysis result may be affected.
Utility model content
The purpose of this utility model is, possibly cannot be arrived by the photosensitive Port detecting of CCD camera for the scattering had due to photon existed in above-mentioned prior art, and the photosensitive mouth of CCD camera detects other light signals except the photon that intermediate discharges when excited state gets back to ground state and affects the defect of final analysis result, there is provided design a kind of biochip supplies analysis, to solve the problem, thus improve the Detection accuracy of biochip.
For achieving the above object, the utility model provides following technical scheme:
A kind of biochip supplies analysis, comprising:
-housing, is provided with dividing plate in described housing, and described dividing plate is provided with through hole, and the cavity in housing is divided into upper chamber and lower chambers by dividing plate, and the below in housing forward end face is provided with outer door,
-bogey, described bogey is objective table, for carrying biochip,
-gearing, described gearing is positioned at the bottom of lower chambers, for drive transfer objective table,
-harvester, described harvester is CCD camera, and described CCD camera is fixed on dividing plate, the photosensitive port of CCD camera is positioned at the top of bulkhead through-hole, the object lens of CCD camera are positioned at directly over objective table, and described CCD camera is connected with CCD camera power supply adaptor
-shade, described shade is two pieces of light shields, and two pieces of light shield symmetries are arranged between dividing plate and gearing, for the light path between airtight objective table and the photosensitive port of CCD camera,
-control device, described control device comprises control circuit board, in order to realize the control to biochip supplies analysis;
-heat abstractor, described heat abstractor is fan, is positioned at upper chamber, and the housing position corresponding with fan is provided with heat dissipation channel;
It is characterized in that: be provided with color filter above the object lens of CCD camera, the top of described color filter is provided with converging lenses.
Preferably, described converging lenses is convex lens; Adopt convex lens as converging lenses, under the prerequisite ensureing convergence effect, save cost.
Preferably, described through hole is manhole.
Preferably, the size of described manhole and the consistent size of the photosensitive port of CCD camera; Avoid CCD camera extraneous light to be detected, thus testing result is had an impact.
Preferably, described gearing comprises transmission platform, motor, transmission accessory whorl and driving belt; Transmission platform installs objective table, transmission platform is connected with shadow shield, shadow shield coordinates with outer door, in order to enclosed interior light transmission passage, the bottom surface of transmission platform is provided with groove, described groove matches with the rotating shaft of transmission accessory whorl, and transmission accessory whorl realizes transmission by the output shaft of driving belt and motor.
Preferably, the side of described transmission accessory whorl is provided with belt wheel briquetting; For connecting belt and objective table and transmitting power.
Preferably, described heat dissipation channel is bar shaped thermovent.
Preferably, described bar shaped thermovent is provided with screen pack; Installing screen pack enters in detector housing to avoid introduced contaminants by heat dissipation channel, to keep cleaning in housing.
The beneficial effects of the utility model are:
1, by installing light shield between dividing plate and gearing, the light path between airtight objective table and the photosensitive port of CCD camera, prevent the photosensitive port of external light influence CCD camera to the collection of the photon discharged in chemical reaction process;
2, utilize the filtering function of color filter, by the impurity photon filtering produced in chemical reaction process, thus avoid impurity photon to affect final analysis judged result, improve Detection accuracy;
3, the aggregation feature of converging lenses is utilized, converge the photon signal discharged in chemical reaction process, prevent photon equilibrium state from arriving outside the sensing range of photosensitive port of CCD camera, thus avoid the undetected situation of photon signal to occur, to improve final Detection accuracy;
In addition, the utility model design concept is reliable, and structure is simple, has application prospect widely.
As can be seen here, the utility model compared with prior art, has substantive distinguishing features and progress, and its beneficial effect implemented also is apparent.
Accompanying drawing explanation
The stereographic map of a kind of biochip supplies analysis that Fig. 1 provides for the utility model.
The right view of a kind of biochip supplies analysis that Fig. 2 provides for the utility model.
The left view of a kind of biochip supplies analysis that Fig. 3 provides for the utility model.
The vertical view of a kind of biochip supplies analysis that Fig. 4 provides for the utility model.
The front elevation of a kind of biochip supplies analysis that Fig. 5 provides for the utility model.
The schematic diagram that the heat dissipation channel of a kind of biochip supplies analysis that Fig. 6 provides for the utility model coordinates with screen pack.
The path channels schematic diagram of a kind of biochip supplies analysis that Fig. 7 provides for the utility model.
Wherein, 1-housing, 2-dividing plate, 3-CCD camera, 4-light shield, 5-transmission platform, 6-objective table, 7-shadow shield, 8-motor, 9-driving belt, 10-outer door, 11-belt wheel briquetting, 12-heat dissipation channel, 13-CCD power supply adaptor, 14-screen pack, 15-fan, 16-object lens, 17-color filter, 18-converging lenses.
Embodiment
Below in conjunction with accompanying drawing, also by specific embodiment, the utility model is elaborated, and following examples are to explanation of the present utility model, and the utility model is not limited to following embodiment.
As shown in Fig. 1 to 7, a kind of biochip supplies analysis that the utility model provides, comprising:
-housing 1, is provided with dividing plate 2 in described housing 1, and described dividing plate 2 is provided with through hole, and the cavity in housing 1 is divided into upper chamber and lower chambers by dividing plate 2, and the below of housing 1 front end face is provided with outer door 10,
-bogey, described bogey is objective table 6, for carrying biochip,
-gearing, described gearing is positioned at the bottom of lower chambers, for drive transfer objective table,
-harvester, described harvester is CCD camera 3, and described CCD camera 3 is fixed on dividing plate 2, the photosensitive port of CCD camera 3 is positioned at the top of bulkhead through-hole, the object lens of CCD camera 3 are positioned at directly over objective table 6, and described CCD camera 3 is connected with CCD camera power supply adaptor 13
-shade, described shade is that two pieces of light shields, 4, two pieces of light shield 4 symmetries are arranged between dividing plate 2 and gearing, for the light path between airtight objective table 6 and the photosensitive port of CCD camera 3,
-control device, described control device comprises control circuit board, in order to realize the control to biochip supplies analysis;
-heat abstractor, described heat abstractor is fan 15, is positioned at upper chamber, and housing 1 position corresponding with fan 15 is provided with heat dissipation channel 12;
Wherein, be provided with color filter 17 above the object lens 16 of CCD camera 3, the top of described color filter 17 is provided with converging lenses 18.
In the present embodiment, described converging lenses 18 is convex lens; Adopt convex lens as converging lenses, under the prerequisite ensureing convergence effect, save cost.
In the present embodiment, described through hole is manhole.
In the present embodiment, the consistent size of the size of described manhole and the photosensitive port of CCD camera; Avoid CCD camera extraneous light to be detected, thus testing result is had an impact.
In the present embodiment, described gearing comprises transmission platform 5, motor 8, transmission accessory whorl and driving belt 9; Transmission platform 5 is installed objective table 6, transmission platform 5 is connected with shadow shield 7, shadow shield 7 coordinates with outer door 10, in order to enclosed interior light transmission passage, the bottom surface of transmission platform 5 is provided with groove, described groove matches with the rotating shaft of transmission accessory whorl, and transmission accessory whorl realizes transmission by driving belt 9 and the output shaft of motor 8.
In the present embodiment, the side of described transmission accessory whorl is provided with belt wheel briquetting 11; For connecting belt and objective table and transmitting power.
In the present embodiment, described heat dissipation channel 12 is bar shaped thermovent.
In the present embodiment, described bar shaped thermovent is provided with screen pack 14; Installing screen pack 14 enters in detector housing 1 to avoid introduced contaminants by heat dissipation channel 12, to keep cleaning in housing 1.
Preferred implementation of the present utility model is only above; but the utility model is not limited thereto; any those skilled in the art can think there is no creationary change; and do not departing from the some improvements and modifications done under the utility model principle prerequisite, all should drop in protection domain of the present utility model.
Claims (8)
1. a biochip supplies analysis, comprising:
-housing, is provided with dividing plate in described housing, and described dividing plate is provided with through hole, and the cavity in housing is divided into upper chamber and lower chambers by dividing plate, and the below in housing forward end face is provided with outer door,
-bogey, described bogey is objective table, for carrying biochip,
-gearing, described gearing is positioned at the bottom of lower chambers, for drive transfer objective table,
-harvester, described harvester is CCD camera, and described CCD camera is fixed on dividing plate, the photosensitive port of CCD camera is positioned at the top of bulkhead through-hole, the object lens of CCD camera are positioned at directly over objective table, and described CCD camera is connected with CCD camera power supply adaptor
-shade, described shade is two pieces of light shields, and two pieces of light shield symmetries are arranged between dividing plate and gearing, for the light path between airtight objective table and the photosensitive port of CCD camera,
-control device, described control device comprises control circuit board, in order to realize the control to biochip supplies analysis;
-heat abstractor, described heat abstractor is fan, is positioned at upper chamber, and the housing position corresponding with fan is provided with heat dissipation channel;
It is characterized in that: be provided with color filter above the object lens of CCD camera, the top of described color filter is provided with converging lenses.
2. biochip supplies analysis according to claim 1, is characterized in that: described converging lenses is convex lens.
3. biochip supplies analysis according to claim 1 and 2, is characterized in that: described through hole is manhole.
4. biochip supplies analysis according to claim 3, is characterized in that: the consistent size of the size of described manhole and the photosensitive port of CCD camera.
5. biochip supplies analysis according to claim 4, is characterized in that: described gearing comprises transmission platform, motor, transmission accessory whorl and driving belt; Transmission platform installs objective table, transmission platform is connected with shadow shield, shadow shield coordinates with outer door, in order to enclosed interior light transmission passage, the bottom surface of transmission platform is provided with groove, described groove matches with the rotating shaft of transmission accessory whorl, and transmission accessory whorl realizes transmission by the output shaft of driving belt and motor.
6. biochip supplies analysis according to claim 5, is characterized in that: the side of described transmission accessory whorl is provided with belt wheel briquetting.
7. biochip supplies analysis according to claim 6, is characterized in that: described heat dissipation channel is bar shaped thermovent.
8. biochip supplies analysis according to claim 7, is characterized in that: described bar shaped thermovent is provided with screen pack.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420437698.9U CN204028008U (en) | 2014-08-05 | 2014-08-05 | Biochip supplies analysis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420437698.9U CN204028008U (en) | 2014-08-05 | 2014-08-05 | Biochip supplies analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204028008U true CN204028008U (en) | 2014-12-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420437698.9U Expired - Lifetime CN204028008U (en) | 2014-08-05 | 2014-08-05 | Biochip supplies analysis |
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| Country | Link |
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| CN (1) | CN204028008U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104198468A (en) * | 2014-08-05 | 2014-12-10 | 曲阜裕隆生物科技有限公司 | Biochip detector |
-
2014
- 2014-08-05 CN CN201420437698.9U patent/CN204028008U/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104198468A (en) * | 2014-08-05 | 2014-12-10 | 曲阜裕隆生物科技有限公司 | Biochip detector |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20180515 Address after: 211199 2 2 Shengan Road, Binjiang Economic Development Zone, Jiangning District, Nanjing, Jiangsu. Patentee after: Nanjing Yulong Biomedical Development Co.,Ltd. Address before: 273100 3 Qufu Tian Bo Road, Qufu Economic Development Zone, Jining, Shandong Patentee before: QUFU YULONG BIOMEDICAL CO.,LTD. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220309 Address after: 200233 fourth floor, 50 plant fourth, Qinzhou North Road, Xuhui District, Shanghai. Patentee after: Shanghai Yulong Biotech Co.,Ltd. Address before: 211199 2 2 Shengan Road, Binjiang Economic Development Zone, Jiangning District, Nanjing, Jiangsu. Patentee before: Nanjing Yulong Biomedical Development Co.,Ltd. |
|
| EE01 | Entry into force of recordation of patent licensing contract | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: SHANGHAI YULONG SHENGUANG MEDICAL LABORATORY Co.,Ltd. Assignor: Shanghai Yulong Biotech Co.,Ltd. Contract record no.: X2023980045714 Denomination of utility model: Biochip detector Granted publication date: 20141217 License type: Common License Record date: 20231102 |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20141217 |