CN203873744U - Esophageal varices noninvasive pressure measuring system - Google Patents
Esophageal varices noninvasive pressure measuring system Download PDFInfo
- Publication number
- CN203873744U CN203873744U CN201420271618.7U CN201420271618U CN203873744U CN 203873744 U CN203873744 U CN 203873744U CN 201420271618 U CN201420271618 U CN 201420271618U CN 203873744 U CN203873744 U CN 203873744U
- Authority
- CN
- China
- Prior art keywords
- pressure
- gastroscope
- esophageal
- measuring system
- probe system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn - After Issue
Links
Abstract
The utility model discloses an esophageal varices noninvasive pressure measuring system. The esophageal varices noninvasive pressure measuring system comprises a gastroscope and further comprises a shiatsu airflow probe system and a laser range finder, wherein the shiatsu airflow probe system is used for producing airflow beams of which the pressure is adjustable. An output air tube of the shiatsu airflow probe system extends into an endoscopic tube of the gastroscope through a gastroscope biopsy hole. The inlet end of the output air tube is provided with a first pressure sensor. The laser range finder obtains reflected light spots of the esophageal vein wall membrane under the action of the shiatsu airflow probe system through an image transmission fiber which extends into the endoscopic tube through the gastroscope biopsy hole. Esophageal vein images collected by an image sensor are sent to a central processor. The esophageal varices noninvasive pressure measuring system is simple in structure, the testing process is short, and therefore the problem that friction between an air bag of an existing device and the vascular wall causes rupture hemorrhage is avoided; in addition, measuring errors are small, and measuring results are accurate and reliable; besides, the pressure measuring system is wide in application range and can be used for pressure measurement of thin and small blood vessels.
Description
Technical field
This utility model relates to biomedical engineering field, particularly a kind of esophageal varicosis noinvasive pressure measuring system.
Background technology
Esophageal varicosis is a kind of common complication of patient with liver cirrhosis, raises and causes the vein collateral circulation of esophagus lower end open mainly due to portal venous pressure, forms the cirso-(EV) to esophagus inwall projection.Annual kainogenesis rate is 7%, and the liver cirrhosis patient of half left and right has occurred in the time of diagnosis.It is hemorrhage that its cardinal symptom is that EV breaks, and annual kainogenesis rate is approximately 12%, wherein 5% betides little EV, and 15% betides large EV.In 1 year EV more hemorrhage incidence rate be 60%, after each EV is hemorrhage, 6 weeks interior mortality rates are 15%～20%, wherein Child A level liver function patient is that 0%, Child C level liver function patient is up to 30%.Therefore for liver cirrhosis patient, how to find in time the hemorrhage high-risk group of EV, look-ahead bleeding tendency is also formulated rational therapeutic scheme and is just seemed particularly important.Various countries scholar attempt by scope levy, the many indexes such as the dynamic (dynamical) ultrasonic index of portal venous flow, azygos vein blood flow, portal venous pressure, EV pressure and HVPG (HVPG) predicts that esophageal variceal vein is hemorrhage, but predictablity rate all can not be satisfactory.HVPG is considered to judge at present that EV forms and predict hemorrhage best index.But HVPG needs jugular vein intubate (danger has wound operation), technical difficulty large (needing radiation to get involved team coordinates), testing cost high (domestic approximately 8000 yuan/time), is difficult to extensively carry out in clinical everyday work
[7].And HVPG detect be sinus hepaticus internal pressure, can not accurately reflect and cause esophageal veins the most direct hemorrhage most important reason, the variation of esophageal veins pressure.In fact, select HVPG predict EV hemorrhage be the caving-in bash being difficult at present under the predicament of safe, accurate, convenient measurement EV pressure.
Since the fifties in last century, show that about numerous researchs of EV pressure too high EV pressure is to cause the EV hemorrhage direct factor that breaks.Utilize respiratory pressure measuring principle to carry out the result demonstration of the adherent Manometric Studies of EV, in the time of EV pressure >14mmHg, hemorrhage incidence rate exceedes 39%, only has 9% patient that Esophagus venous bleeding occurs when pressure <14mmHg.EV pressure energy directly reflects the hemodynamic situation of EV, is proportionate, and there is no final conclusion with the dependency of HVPG with antiotasis and azygos vein blood flow.Human body EV piezometry is all carried out under scope, has at present two kinds of technology, i.e. intravenous pressure measurement and vein measuring pressure from outside.The former measures pressure by fine needle aspiration cirso-, is the recognized standard pressure testing method, is first reported by Palmer in nineteen fifty-one.But the method has its fatal weakness in scientific research and clinical practice: the first, can not repeat pressure measurement; The second, there is 1/3 patient to cause massive hemorrhage because of puncture; The 3rd, puncture pressure measuring can cause that antibacterial infects.So the method seldom adopts at present.Noinvasive (Wicresoft) manometric technique outside vein is the main stream approach of current EV Manometric Studies
[15].Nineteen eighty-two Switzerland scholar Mosimann has introduced and has utilized respiratory pressure measuring principle to carry out the new technique of EV blood vessel measuring pressure from outside.Its ultimate principle is according to being: because varicose vein wall is very thin and do not have peripheral tissues to support, therefore the pressure of extraneous compressing vein equals vein when intrinsic pressure, and deformation will occur wall of vein.Various countries scholar updates this technology afterwards, changes the air of inputting in gas return path into nitrogen on the one hand and solidifies to prevent water steam, on the other hand probe is done less and less.Liu of The Third Xiangya Hospital of Central South University waterside sun and Zhu shine red research team and are devoted to the pressure measurement of esophageal variceal vein noinvasive and hemorrhage prediction always, and stand-alone development has been developed through the adherent measuring cell of the non-invasive esophageal variceal vein of scope.Compared with external device, this instrument has mainly been done following improvement: 1. adopt single tube pressure balance method manometric technique, make gas export balance more; 2. measure pressure with two high sensitivity pressure and differential pressure pickup and change, it is more accurate to make to measure; 3. gas-sensing probe pressure measurement area only 1.2mm make the esophageal variceal vein pressure that calibrates less become possibility.This instrument is through experiment in vitro, zoopery and clinical trial, and with the comparative study of direct puncture pressure measuring, all show that this choice specimen of calligraphy wall pressure measurement and normal pressure have fabulous dependency relation.
Switzerland scholar Gertsch in 1987 etc. on the basis of respiratory pressure measuring principle, the non-invasive esophageal variceal vein air bag manometry of having utilized cuff pressure measuring principle utility model.Its method is that an air bag is arranged under gastroscope head, and a plastic catheter is connected with air bag by biopsy hole, and the other end of conduit is connected with a 50ml syringe and electronic pressure gauge by tee T.When inspection, gastroscope is inserted to distal esophagus, syringe gas injection rear gasbag is full gradually, by the visible EV of transparent airbag wall.In the time that air bag contacts with blood vessel wall, balloon tamponade is flat to blood vessel wall, and the value that electronic pressure gauge records is exactly that EV is intrinsic pressure.After Import computer video processing technique, it is more and more objective and accurate that the method has also become at present.Medical University Of Anhui is permitted to build the bright and designed esophagus in computer vision varicose pressure testing system of team Kong Derun can, after real-time gastroscope image, gasbag pressure synchronous acquisition, synthesize a video file by software unit by gentle the video signal of gastroscope bag pressure signal.Operator only need determine the cirso-that will follow the tracks of and cover its upper gasbag surface tag line, system will be pressed the moment of falling into cirso-by Autonomous determination air bag, obtain the pressure in air bag now by later stage offline image processing again, thereby realize the automatic accurate measurement of EV pressure.The experiment in vivo and vitro of this system all shows between EV pressure and HVPG, to have good dependency, and also closely related between other hemorrhages.More accurate compared with air bag pressure measurement for large EV for diameter, can replace venipuncture pressure measurement, but poor for the less EV air bag pressure measurement accuracy of diameter.
But, although the outer non-invasive pressure testing method of above two large class veins all has the relevant report of many experiment in vitro, zoopery and clinical trial, confirm that these two kinds of pressure testing methods have clinical meaning and feasibility.But first two kinds of methods all need directly to contact vein blood vessel, in pressure measurement process, there is the iatrogenic EV hemorrhage risk of breaking.Secondly the two has all ignored the variation of varicose vein wall tension force in pressure measurement process, and cannot overcome swallow, the impact of physiological process on measurement result such as esophagus peristalsis and cardia motion, cause accuracy not high.And the accurately pressure of a certain characteristic point of location survey EV of air bag manometry, there is larger limitation.Because the formation and development of EV is a progressive process, and the large EV of the diameter hemorrhage danger of breaking is extremely urgent, must treat as early as possible and has lost necessity of prediction.Therefore, for prediction EV the more important thing is for hemorrhage find a kind of safe, accurate, reproducible endoscope and image processing device for measuring, the pressure of little EV, form the more prognoses system of comprehensive and reasonable practicality taking EV pressure as core index and in conjunction with some auxiliary characteristicss again, thereby be more in depth familiar with, EV produces, hemorrhage pathophysiological mechanism breaks.
So in the pressure tester existing at present, though have Non-Invasive feature, current device still has following deficiency:
(1) although. adherent pressure measurement noinvasive, but belong to contact type measurement, pressure measurement process comprise eject the contact of air bag, Chong Qi Stickers wall, pressurising is measured, is received the processes such as capsule, has the intrinsic inconvenience of contact type measurement mode, as test process is long, air bag and blood vessel wall friction cause break hemorrhage etc.;
(2). what when air bag pressure measurement, see by video image is air bag inwall, even if air bag is transparent, also exists reflectively, and the problem such as absorption spectrum is inconsistent, can't see real biological endoscopic picture, is not easy to doctor's visual Diagnosis;
(3). when air bag pressure measurement, air bag is not only close to tested vein, also oppresses whole esophagus inner chamber, and total force is large, causes tested vein blood vessel integrated moving, and state changes, and causes measurement error;
(4). when air bag pressure measurement, rely on video image to judge the state that vein " just subsides ", because pick-up lens is uncertain to the visible sensation distance at vein collapse place, cause the amplification of image inconsistent, judge that by people or Software of Computer Vision the state of " just subsiding " all exists uncertain error no matter be;
(5). existing device visual field is all larger, to tiny cirso-pressure measurement difficulty;
(6). esophageal peristalsis impact is measured: existing device is many, and based on PC processing video data, processing procedure is long, have or even process afterwards, in the time that discovery esophageal peristalsis affects measurement data, have little time again to measure.
Utility model content
Technical problem to be solved in the utility model is, for the deficiencies in the prior art, provides a kind of esophageal varicosis noinvasive pressure measuring system, provides a kind of hardware to realize basis for solving the problems of the technologies described above.
For solving the problems of the technologies described above, the technical scheme that this utility model adopts is: a kind of esophageal varicosis noinvasive pressure measuring system, comprise gastroscope, and also comprise finger pressure air-flow probe system, laser range finder; The gas outlet tube of described finger pressure air-flow probe system by gastroscope movable detecting hole stretch into described gastroscope in peep in pipe; The arrival end of described gas outlet tube is provided with the first pressure transducer; The image transmission optical fibre of described laser range finder by described gastroscope movable detecting hole stretch into described gastroscope in peep in pipe; The distance of peeping in the described gas outlet tube port of export, image-carrying fiber bundle end face, described gastroscope between imageing sensor and the esophageal veins to be measured of end surfaces is 7～15mm; Described gastroscope, finger pressure air-flow probe system, laser range finder are all electrically connected with described central processing unit.
Gas outlet tube diameter of the present utility model very little (< 3 mm), finger pressure air-flow probe system acts on the gross pressure very little (<15g) of described esophageal veins wall, to prevent from disturbing tested esophageal veins.
Compared with prior art, the beneficial effect that this utility model has is: this utility model is simple in structure, has avoided existing apparatus air bag and blood vessel wall friction to cause the hemorrhage problem of breaking; This utility model is applied widely, can be for the pressure measurement of minute blood vessel.
Brief description of the drawings
Fig. 1 is this utility model one example structure schematic diagram.
Detailed description of the invention
As shown in Figure 1, this utility model one embodiment comprises gastroscope, also comprises finger pressure air-flow probe system, laser range finder for generation of the adjustable air flow stream of pressure; The gas outlet tube 1 of described finger pressure air-flow probe system by gastroscope movable detecting hole 2 stretch into described gastroscope in peep pipe 3 in; The arrival end of described gas outlet tube 1 is provided with the first pressure transducer 4; Described laser range finder 5 obtains the flare of esophageal veins wall film under the effect of described finger pressure air-flow probe system by image transmission optical fibre 6, described image transmission optical fibre 6 stretches in described and peeps in pipe 3 through described gastroscope movable detecting hole 2; Described gas outlet tube 1 port of export, 6 one end faces of image transmission optical fibre, the distance of peeping in described between imageing sensor and the esophageal veins 7 to be measured of pipe 3 end faces are 7～15mm; The esophageal veins image of described imageing sensor collection is sent in central processing unit 8; Described central processing unit 8 is controlled described finger pressure air-flow probe system and is produced air flow stream, the flare that simultaneously utilizes described laser range finder measurement to obtain calculates the amount of recess Δ h of esophageal veins wall film under the effect of described finger pressure air-flow probe system, Δ h=kd, wherein the span of k is 1.02～1.12.
Finger pressure air-flow probe system of the present utility model comprises the gas bomb 10 that inflator pump 9 and arrival end are communicated with described inflator pump, described gas bomb 10 ports of export are communicated with described gas outlet tube 1 arrival end by pipeline, and pipeline between described gas bomb 10 ports of export and described gas outlet tube 1 arrival end is provided with control damper 11; In described gas bomb 10, be provided with the second pressure transducer 12; Described the second pressure transducer 12, inflator pump 9 are all electrically connected with described central processing unit 8.
The second pressure transducer detects gas bomb internal gas pressure P in real time
0, work as P
0while being less than setting value, central processing unit starts inflator pump inflation, to ensure that gas bomb has enough tolerance and air pressure; When measurement, control control damper and produce triangular wave pulse pneumatic with some cycles, thereby form periodically pulsing air pressure, form finger pressure airflow function in vein blood vessel through gas outlet tube.Gas outlet tube diameter very little (< φ 3 mm), acts on very nearly (about 8mm) of venous blood tube wall, the gross pressure little (<15g) of finger pressure probe vasoactive wall, thereby can not disturb measurand.The operation principle of finger pressure air-flow probe system is: by scalable air pump, produce the adjustable air flow stream of pressure, the impulsive force of air flow stream produces active force to blood vessel wall, simultaneously, according to the functional relationship of the stream pressure at diverse location, finger pressure air-flow probe system gathers the stream pressure of a certain position, thereby can calculate the stream pressure value of other positions.
In this utility model, air reservoir capacity is 3L, adopts the steel plate that thickness is 3MM to make, and surface is through paint baking, safe air pressure 15KG.Air reservoir has four fixed supports, is furnished with rubber buffering mounting seat.On air reservoir with relief valve, drain valve, air reservoir gas outlet is with oil water separator.Drain valve and oil water separator need to regularly do draining blowdown and safeguard.
If finger pressure air-flow probe effect vein blood vessel wall force value is P
2, we are the air pressure P that requires to pulse
2large minor control field meets following formula:
0 < P
2 < Max P
2 （1）
Max P in formula
2to make blood vessel wall film amount of recess be greater than the corresponding air pressure of the depressions in features degree of depth.
The real-time detected air pressure P of the first pressure transducer simultaneously
1, by finger pressure probe structure and Hydrodynamics Theory, we know:
P
2 = f（P
1，h，φ） （2）
Impose on the air pressure P on vein blood vessel
2not only active air pressure P
1relevant, also relevant with the big or small φ of the relative area of exerting pressure with the distance h of exerting pressure.In this programme, gas outlet tube diameter is less than 2 mm, arranges tested vein blood vessel diameter and is greater than 2 mm, ensures that the distance h of initially exerting pressure is true stable constant value (=10 mm) simultaneously, thereby (3-5) formula is converted into by laser fiber distance measuring sensor:
P
2 = f
1（P
1） （3）
Under definite pressure measurement operating condition, the mode that can demarcate by measured test, obtains (3) formula of expressing with form; In test in the future, we can detect to obtain air pressure P by load cell-1 like this
1value, then look into (3) formula form, obtain pressure valve P on vein blood vessel
2.
Examination venous blood tube wall part of the force, venous blood tube wall quality and acceleration are all very little, can ignore, and we can obtain equilibrium equation:
P
4 = P
2 + P
3 （4）
Wherein:
P
4: be cirso-internal pressure, final measuring object of the present utility model;
P
2: for finger pressure air-flow probe acts on the air pressure in cirso-blood vessel wall,
Record P by the first pressure transducer
1after table look-up and obtain;
P
3: be cirso-blood vessel wall film tension force,
When wall film depression and amount of recess are less than depressions in features depth delta h
0time be zero.
Because being adopts pulse pneumatic, in formula (4), each power size is all time dependent, and we should be specifically noted that cirso-blood vessel wall film tension force P
3direction can just can be born, and P
4, P
2direction be constant.
Active flow pressure is 0 o'clock, blood flow in blood vessel wall film constraint blood vessel, P
3for just; In the time that active finger pressure stream pressure increases gradually, P
3for just and gradually diminishing, until be zero; Now cirso-blood vessel wall film starts depression, when reaching depressions in features depth delta h
0time, P
3be still zero; Afterwards, initiatively finger pressure stream pressure continues to increase gradually to MaxP
2, P
3stride across zero point, direction is reversed negative, and value becomes large gradually.
We detect cirso-blood vessel wall film cup depth in real time by laser fiber distance measuring sensor, are less than Δ h when cup depth is greater than zero
0time, have:
P
3 = 0
（5）
P
4 = P
2 （6）
The record P that the first pressure transducer is measured this moment
1value, then table look-up and record P
2, obtain cirso-pressure value P by (6) formula
4.
Central processing unit of the present utility model adopts OMAP-4430-1GHz double-core Cortex-A9 processor.
Claims (4)
1. an esophageal varicosis noinvasive pressure measuring system, comprises gastroscope, it is characterized in that, also comprises finger pressure air-flow probe system, laser range finder; The gas outlet tube of described finger pressure air-flow probe system by gastroscope movable detecting hole stretch into described gastroscope in peep in pipe; The arrival end of described gas outlet tube is provided with the first pressure transducer; The image transmission optical fibre of described laser range finder by described gastroscope movable detecting hole stretch into described gastroscope in peep in pipe; The distance of peeping in the described gas outlet tube port of export, image-carrying fiber bundle end face, described gastroscope between imageing sensor and the esophageal veins to be measured of end surfaces is 7～15mm; Described gastroscope, finger pressure air-flow probe system, laser range finder are all electrically connected with central processing unit.
2. esophageal varicosis noinvasive pressure measuring system according to claim 1, it is characterized in that, described finger pressure air-flow probe system comprises the gas bomb that inflator pump and arrival end are communicated with described inflator pump, the described gas bomb port of export is communicated with described gas outlet tube arrival end by pipeline, and pipeline between the described gas bomb port of export and described gas outlet tube arrival end is provided with control damper; In described gas bomb, be provided with the second pressure transducer; Described the second pressure transducer, inflator pump are all electrically connected with described central processing unit.
3. esophageal varicosis noinvasive pressure measuring system according to claim 1 and 2, is characterized in that, described gas outlet tube diameter < 3 mm.
4. esophageal varicosis noinvasive pressure measuring system according to claim 3, is characterized in that, described finger pressure air-flow probe system acts on the gross pressure <15g of described esophageal veins wall.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420271618.7U CN203873744U (en) | 2014-05-26 | 2014-05-26 | Esophageal varices noninvasive pressure measuring system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420271618.7U CN203873744U (en) | 2014-05-26 | 2014-05-26 | Esophageal varices noninvasive pressure measuring system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203873744U true CN203873744U (en) | 2014-10-15 |
Family
ID=51674306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420271618.7U Withdrawn - After Issue CN203873744U (en) | 2014-05-26 | 2014-05-26 | Esophageal varices noninvasive pressure measuring system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203873744U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103976722A (en) * | 2014-05-26 | 2014-08-13 | 中南大学湘雅三医院 | Non-invasive pressure measuring method for esophageal varices |
| CN109567751A (en) * | 2018-11-15 | 2019-04-05 | 陈圣开 | A kind of puncture needle and its application method for measurement cirrhosis hardness in art |
-
2014
- 2014-05-26 CN CN201420271618.7U patent/CN203873744U/en not_active Withdrawn - After Issue
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103976722A (en) * | 2014-05-26 | 2014-08-13 | 中南大学湘雅三医院 | Non-invasive pressure measuring method for esophageal varices |
| CN109567751A (en) * | 2018-11-15 | 2019-04-05 | 陈圣开 | A kind of puncture needle and its application method for measurement cirrhosis hardness in art |
| CN109567751B (en) * | 2018-11-15 | 2021-09-24 | 陈圣开 | Puncture needle for measuring cirrhosis hardness in operation |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102599892A (en) | Intraperitoneal pressure monitoring system and monitoring method | |
| Hoff et al. | Mucosal blood flow measurements using laser Doppler perfusion monitoring | |
| CN106923807A (en) | Based on the method and system that temperature is corrected to blood pressure measurement | |
| CN203873744U (en) | Esophageal varices noninvasive pressure measuring system | |
| CN104042200B (en) | A kind of non-invasive monitoring devices and methods therefor of arteriotony by shooting | |
| CN102908133A (en) | Esophagus vein blood pressure measuring instrument | |
| CN103961076B (en) | A kind of esophageal varicosis non-invasivetesting system | |
| CN203873747U (en) | Automatic reading type mercury manometer | |
| CN202477681U (en) | Optical fiber sensor-based digestive tract pressure measuring device for medical clinic | |
| KR101454201B1 (en) | Test Apparatus, Test Method and Adjusting Method for Automatic Sphygmomanometer | |
| CN216455611U (en) | Glaucoma aqueous humor drainage device drainage valve opening and closing pressure detection system | |
| CN103976722B (en) | A kind of esophageal variceal vein non-invasivetesting method | |
| CN104490364A (en) | Optical fiber finger for detecting flexibility of prostate and detection method | |
| WO2019052584A2 (en) | Human tissue quasi-elastic coefficient and elasticity measurement methods and device | |
| CN107714087A (en) | A kind of peripheral vascular detector of the mechanical pressure measurement of ultrasonic Doppler pen probe | |
| CN203841683U (en) | Vascular endothelial function analysis system | |
| JP2007111244A (en) | Blood circulation state measuring apparatus | |
| CN203016931U (en) | Esophagus vein blood pressure measuring instrument | |
| CN201524071U (en) | Device detecting physiologic compliance of blood vessels | |
| Cheatham et al. | Measuring intra-abdominal pressure outside the ICU: validation of a simple bedside method | |
| CN207703282U (en) | A kind of fine liquid flow measurement device based on displacement measurement | |
| CN207409177U (en) | Penis erecting strength Simulation Diagnosis instrument | |
| CN202604817U (en) | Novel intra-abdominal pressure measuring device | |
| CN204274433U (en) | A kind of cuff of electric sphygmomanometer | |
| TWI612939B (en) | Method and device for detecting blood flow rate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20141015 Effective date of abandoning: 20160706 |
|
| AV01 | Patent right actively abandoned |
Granted publication date: 20141015 Effective date of abandoning: 20160706 |
|
| C25 | Abandonment of patent right or utility model to avoid double patenting |