CN106923807A - Based on the method and system that temperature is corrected to blood pressure measurement - Google Patents
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Abstract
This application discloses a kind of method being corrected to blood pressure measurement based on temperature, including：Formula relationship between blood pressure and pulse ripple signal fisrt feature amount in itself is determined by the derivation of equation；Theoretical pressure value is calculated according to formula；Actual blood pressure value is measured at different temperatures；Blood pressure compensation rate based on temperature is determined by relatively more described actual blood pressure value and the theoretical pressure value, the compensation rate contains blood pressure and pulse ripple signal second feature amount in itself；The pressure value for measuring is corrected using the blood pressure compensation rate.Disclosed herein as well is a kind of system being corrected to blood pressure measurement based on temperature.The application characterizes temperature variations by using the pulse wave signal rule that feature is varied with temperature in itself, and temperature change is compensated to the error that blood pressure measurement is caused using the rule, the automatic correction based on temperature-compensating can be realized to blood pressure measurement.
Description
Technical Field
The application relates to the field of medical care, in particular to a method and a system for correcting a blood pressure measurement value based on temperature.
Background
Measuring blood pressure is a basic method for understanding health and observing disease conditions, and is particularly necessary for middle-aged and elderly people with cardiovascular diseases.
There are two main categories of measuring blood pressure, invasive and non-invasive. Invasive measurement is a direct measurement method in which a catheter is inserted into the artery and the arterial pressure is measured by a transducer connected to a fluid column. The method requires professional medical personnel to operate, is high in cost and is easy to cause medical risks such as bacterial infection and blood loss.
Non-invasive measurement is an indirect measurement method. The method is safe, convenient and comfortable to use, and is a common method for measuring blood pressure in hospitals at present. This method is also used in the home by an increasing number of patients who need to monitor blood pressure for a long period of time. Consumers using non-invasive blood pressure meters are constantly increasing as the public increasingly recognizes that hypertension is a serious health hazard, as well as the importance of early diagnosis and treatment. Non-invasive measurement is mainly performed by three methods: pulse sphygmomanometers, tone measuring sphygmomanometers, and sphygmomanometers based on the pulse wave transmission time.
There are two kinds of measurement methods for pulse sphygmomanometers, one is an auscultation method, and the other is an oscillation method. The auscultation method is based on the collection of the korotkoff sounds and the whole device consists of an inflatable cuff, a mercury manometer (in recent years also an electronic pressure transducer) and a stethoscope. When measuring the blood pressure of an upper limb, driving the air in the sleeve strap to be exhausted in advance, then winding the sleeve strap on the upper arm flatly and without folds, feeling the pulse of the brachial artery, placing a chest piece of the stethoscope at the position, opening a mercury switch, when the sleeve strap is inflated by a balloon with a movable valve, immediately moving a mercury column or a pointer, stopping inflation when the mercury column rises to a default value, then slightly opening the balloon movable valve to deflate slowly, slowly descending the mercury column (turning the pointer), observing the scale of the movement of the mercury column or the pointer at the moment, and if a first sound of the brachial artery is heard, the scale is systolic blood pressure, which is called systolic pressure for short; when the mercury drops to the point that the sound is suddenly weakened or inaudible, the scale indicates diastolic blood pressure, referred to as diastolic pressure for short. However, this method can only determine systolic and diastolic pressures and is not suitable for some patients with weak or even inaudible 5 th korotkoff sounds.
The oscillation method can make up for the above-mentioned deficiencies of the auscultation method, and can also measure blood pressure for patients with weak Korotkoff sounds. When in use, the cuff is flatly and non-wrinkled wound on the upper arm, and the cuff is inflated and deflated. The blood pressure value is determined by measuring the amplitude of the oscillations of the pressure in the inflated cuff, which are caused by the constriction and dilation of the arterial blood vessel. The values of systolic, mean, and diastolic pressures can be obtained from monitoring the pressure in the cuff as the cuff is slowly deflated. The average pressure corresponds to the pressure in the attenuating device of the cuff at the moment of the peak of the envelope. Systolic pressure is typically estimated as the pressure in the decaying turn of the cuff at a time before the peak of the envelope corresponding to the amplitude of the envelope being equal to a proportion of the peak amplitude. The diastolic pressure is typically estimated as the pressure in the attenuating device of the cuff at a time after the peak of the envelope corresponding to the amplitude of the envelope being equal to a proportion of the peak amplitude. The use of different ratio values may affect the accuracy of the blood pressure measurement.
Most products on the market currently adopt an auscultation method or an oscillation method. However, both methods require inflation and deflation of the cuff, making frequent and continuous measurements difficult. Moreover, the frequency of the measurements is limited by the time required to comfortably inflate and deflate the cuff and the time required to deflate the cuff when the measurements are taken. Typically, a complete blood pressure measurement takes about 1 minute. In addition, the size of the cuff size also has an effect on the measurement of blood pressure.
The basic principle of the tonometer is as follows: when the blood vessel is pressed by an external object, the axial stress of the blood vessel wall is eliminated, and the internal pressure and the external pressure of the blood vessel wall are equal. The artery is typically pressurized, flattened, and the pressure at which the artery remains flattened is recorded. This pressure is measured using a set of pressure sensor arrays placed on the superficial arteries and the patient's pressure is calculated therefrom. However, this method has disadvantages in that the cost of the sensor used is high and the measurement accuracy thereof is easily affected by the measurement position.
The blood pressure is determined according to the relationship between the arterial blood pressure and the pulse wave transmission speed by the principle that when the blood pressure rises, the blood vessel expands and the pulse wave transmission speed is increased, and conversely, the pulse wave transmission speed is decreased. In use, the sphygmomanometer collects a photoplethysmography signal through a photoelectric sensor placed on a fingertip, calculates a pulse wave transmission speed (represented by pulse wave transmission time) by utilizing the relation between a reference point in the photoplethysmography signal and a reference point in a electrocardiosignal, and further calculates an arterial blood pressure value. The method can provide a simple and easy-to-use blood pressure measuring device, has low development cost, small volume and low power consumption, and can realize long-time continuous measurement of the arterial blood pressure.
However, before measuring blood pressure using a sphygmomanometer based on a photoplethysmography signal, a calibration with a standard sphygmomanometer is required, that is, a relationship between blood pressure and pulse wave transmission time needs to be found, and then a blood pressure value is measured from the relationship using the actually measured pulse wave transmission time. Therefore, there is a possibility that a problem arises in that the photoplethysmographic signal is acquired from a portion of the extremity (e.g., a fingertip) of the subject, which is more susceptible to the influence of the extremity temperature. If a change in temperature occurs at the time of measurement after calibration, the signal is more susceptible to the tip temperature. If the temperature changes during the measurement after calibration, the relationship between the blood pressure and the pulse wave transmission time determined during calibration will change, thereby affecting the measurement result of the blood pressure value.
Disclosure of Invention
The application provides a method and a system for correcting a blood pressure measurement value based on temperature.
According to a first aspect of the present application, there is provided a method of correcting a blood pressure measurement based on temperature, comprising:
determining a formula relation between the blood pressure and the characteristic quantity of the pulse wave signal through formula derivation;
calculating a theoretical blood pressure value according to a formula;
measuring actual blood pressure values at different temperatures;
determining a temperature-based blood pressure compensation amount by comparing the actual blood pressure value with the theoretical blood pressure value, wherein the compensation amount contains characteristic amounts of the blood pressure and the pulse wave signal;
and correcting the measured blood pressure value by using the blood pressure compensation amount.
In the above method, the characteristic quantities of the blood pressure and the pulse wave signal themselves include time domain characteristics, derivative signal characteristics, and frequency domain characteristics.
In the above method, the derivative signal characteristic includes a second-order amplitude value of a top point of the pulse wave signal.
In the above method, the formula relationship includes:
the first characteristic quantity is PTT, PTT is the conduction time of the pulse wave from the heart to the finger, delta BP is the systolic pressure, d is the distance from the heart to the finger, g is the gravity acceleration, h is the distance from the heart to the finger tip, rho is the concentration of blood, and PTT is the conduction time of the pulse wave from the heart to the finger;
if the blood pressure compensation amount is C × Dm, the blood pressure formula containing the blood pressure compensation amount is:
the second characteristic quantity is Dm, the Dm is a second-order amplitude value of the top end point of the pulse wave signal, C is a temperature compensation constant of systolic pressure, and C is obtained through calculation.
In the above method, the step of calculating the temperature compensation constant includes:
measuring a plurality of groups of actual blood pressure values, substituting the second-order amplitude values of the top end points of the pulse wave signals during each measurement, and calculating to obtain a plurality of temperature compensation constants;
and calculating the average value of the plurality of temperature compensation constants, wherein the average value is the temperature compensation constant.
According to a second aspect of the present application, there is provided a system for correcting a blood pressure measurement based on temperature, comprising:
the derivation module is used for deriving and determining a formula relation between the blood pressure and the characteristic quantity of the pulse wave signal per se through a formula;
the processing module is used for calculating a theoretical blood pressure value according to a formula, measuring an actual blood pressure value at different temperatures, and determining a blood pressure compensation quantity based on temperature by comparing the actual blood pressure value with the theoretical blood pressure value, wherein the compensation quantity contains characteristic quantities of the blood pressure and the pulse wave signal;
and the correction module is used for correcting the measured blood pressure value by using the blood pressure compensation quantity.
In the above system, the characteristic quantities of the blood pressure and pulse wave signals themselves include time domain characteristics, derivative signal characteristics, and frequency domain characteristics.
In the above system, the derivative signal characteristic includes a second-order amplitude of a top point of the pulse wave signal.
In the above system, the formula relationship includes:
the first characteristic quantity is PTT, PTT is the conduction time of the pulse wave from the heart to the finger, delta BP is the systolic pressure, d is the distance from the heart to the finger, g is the gravity acceleration, h is the distance from the heart to the finger tip, rho is the concentration of blood, and PTT is the conduction time of the pulse wave from the heart to the finger;
if the blood pressure compensation amount is C × Dm, the blood pressure formula containing the blood pressure compensation amount is:
the second characteristic quantity is Dm, the Dm is a second-order amplitude value of the top end point of the pulse wave signal, C is a temperature compensation constant of systolic pressure, and C is obtained through calculation.
In the system, the processing module is further configured to measure a plurality of groups of actual blood pressure values, substitute the second-order amplitude value of the top end point of the pulse wave signal during each measurement, and obtain a plurality of temperature compensation constants through calculation; and calculating the average value of the plurality of temperature compensation constants, wherein the average value is the temperature compensation constant.
Due to the adoption of the technical scheme, the beneficial effects of the application are as follows:
in the specific implementation mode of the application, the theoretical blood pressure value is calculated according to a formula, and then the actual blood pressure value is measured at different temperatures; the blood pressure compensation quantity based on the temperature is determined by comparing the actual blood pressure value with the theoretical blood pressure value, the blood pressure compensation quantity is used for correcting the measured blood pressure value, the temperature change condition is represented by the rule that the characteristics of the pulse wave signal change along with the temperature, the error caused by the temperature change to the blood pressure measurement is compensated by the rule, and the automatic correction based on the temperature compensation can be realized on the blood pressure measurement value.
Drawings
FIG. 1 is a flow chart of the method of the present application in one embodiment;
FIG. 2 is a schematic view of the system of the present application in one embodiment.
Detailed Description
The present application will be described in further detail below with reference to the accompanying drawings by way of specific embodiments.
The first embodiment is as follows:
as shown in fig. 1, one embodiment of the method for correcting a blood pressure measurement value based on temperature according to the present application includes the following steps:
step 102: the formula relationship between the blood pressure and the characteristic quantity of the pulse wave signal itself is determined by formula derivation.
F＝ΔBP·a ⑵
The method has the advantages that:
wherein the first characteristic quantity is PTT, PTT is a transit time of a pulse wave from the heart to the finger, F is a blood application force, d is a distance from the heart to the finger, m is a mass of blood, v is a velocity of the pulse, g is a gravitational acceleration, h is a distance from the heart to the fingertip (specifically, a distance from the heart to the fingertip), a is a cross-sectional area of a blood vessel, ρ is a concentration of blood, and Δ BP is a systolic pressure.
Step 104: and calculating a theoretical blood pressure value according to a formula.
Substituting the PTT value into a formula three, and calculating a theoretical blood pressure value.
Step 106: the actual blood pressure values were measured at different temperatures.
Step 108: the temperature-based blood pressure compensation amount is determined by comparing the actual blood pressure value with the theoretical blood pressure value, and the compensation amount contains the blood pressure and the characteristic amount of the pulse wave signal itself.
In one embodiment, the feature quantities of the blood pressure and the pulse wave signal themselves include time domain features, derivative signal features, and frequency domain features. The derivative signal characteristics include first and second magnitudes of the apex of the pulse wave signal.
The second derivative amplitude of the top end point of the pulse wave signal recorded during the blood pressure measurement calibration is utilized to perform temperature compensation correction on the blood pressure measurement result, so that an accurate blood pressure measurement result is obtained.
Multiple tests prove that under the condition of constant blood pressure and temperature rise, the pulse wave conduction rate is accelerated, the time is shortened, and the formula is used for verifying that the blood pressure is constantThe calculated blood pressure value will be larger than the true blood pressure, so a temperature compensation term (C x Dm) is needed. Dm decreases with increasing temperature, so that the temperature compensation term can be increased to compensateMaintained at true levels, C x Dm was chosen as the temperature compensation term.
In formula ⑶, d is further considered to be 0.6 times the height H, and ρ is approximately 1035kg/m2G is approximately 9.18m/s2Obtaining the blood pressure formula:
wherein,
the blood pressure formula with the temperature compensation term is:
wherein, C is the temperature compensation constant of the systolic pressure, the second characteristic quantity is Dm, and Dm is the second-order amplitude of the top end point of the pulse wave signal.
The step of calculating the temperature compensation constant comprises:
measuring a plurality of groups of actual blood pressure values, substituting the second-order amplitude values of the top end points of the pulse wave signals during each measurement, and calculating to obtain a plurality of temperature compensation constants;
and calculating the average value of the plurality of temperature compensation constants, wherein the average value is the temperature compensation constant.
Step 110: the measured blood pressure value is corrected using the blood pressure compensation amount.
Example two:
as shown in FIG. 2, one embodiment of the system for correcting blood pressure measurement based on temperature includes a derivation module, a processing module, and a correction module. And the derivation module is used for deriving and determining a formula relation between the blood pressure and the characteristic quantity of the pulse wave signal per se through a formula. And the processing module is used for calculating a theoretical blood pressure value according to a formula, measuring an actual blood pressure value at different temperatures, and determining a blood pressure compensation quantity based on the temperature by comparing the actual blood pressure value with the theoretical blood pressure value, wherein the compensation quantity contains characteristic quantities of the blood pressure and the pulse wave signal. And the correction module is used for correcting the measured blood pressure value by using the blood pressure compensation quantity.
F＝ΔBP·a ⑵
The method has the advantages that:
wherein the first characteristic quantity is PTT, PTT is a transit time of a pulse wave from the heart to the finger, F is a blood application force, d is a distance from the heart to the finger, m is a mass of blood, v is a velocity of the pulse, g is a gravitational acceleration, h is a distance from the heart to the fingertip (specifically, a distance from the heart to the fingertip), a is a cross-sectional area of a blood vessel, ρ is a concentration of blood, and Δ BP is a systolic pressure.
In one embodiment, the feature quantities of the blood pressure and the pulse wave signal themselves include time domain features, derivative signal features, and frequency domain features. The derivative signal characteristics include first and second magnitudes of the apex of the pulse wave signal.
The second derivative amplitude of the top end point of the pulse wave signal recorded during the blood pressure measurement calibration is utilized to perform temperature compensation correction on the blood pressure measurement result, so that an accurate blood pressure measurement result is obtained.
Multiple tests prove that under the condition of constant blood pressure and temperature rise, the pulse wave conduction rate is accelerated, the time is shortened, and the formula is used for verifying that the blood pressure is constantThe calculated blood pressure value will be larger than the true blood pressure, so a temperature compensation term (C x Dm) is needed. Dm decreases with increasing temperature, so that the temperature compensation term can be increased to compensateMaintained at true levels, C x Dm was chosen as the temperature compensation term.
In formula ⑶, d is further considered to be 0.6 times the height H, and ρ is approximately 1035kg/m3G is approximately 9.18m/s2Obtaining the blood pressure formula:
wherein,
the blood pressure formula with the temperature compensation term is:
wherein, C is the temperature compensation constant of the systolic pressure, the second characteristic quantity is Dm, and Dm is the second-order amplitude of the top end point of the pulse wave signal.
In one embodiment, the processing module is further configured to measure a plurality of sets of actual blood pressure values, substitute the second-order amplitude value of the top end point of the pulse wave signal during each measurement, and obtain a plurality of temperature compensation constants through calculation; and calculating the average value of the plurality of temperature compensation constants, wherein the average value is the temperature compensation constant.
The foregoing is a more detailed description of the present application in connection with specific embodiments thereof, and it is not intended that the present application be limited to the specific embodiments thereof. It will be apparent to those skilled in the art from this disclosure that many more simple derivations or substitutions can be made without departing from the spirit of the disclosure.
Claims (10)
1. A method for correcting a blood pressure measurement based on temperature, comprising:
determining a formula relation between the blood pressure and the first characteristic quantity of the pulse wave signal through formula derivation;
calculating a theoretical blood pressure value according to a formula;
measuring actual blood pressure values at different temperatures;
determining a temperature-based blood pressure compensation amount by comparing the actual blood pressure value and the theoretical blood pressure value, the compensation amount containing a second characteristic amount of the blood pressure and the pulse wave signal itself;
and correcting the measured blood pressure value by using the blood pressure compensation amount.
2. The method for correcting a blood pressure measurement based on temperature of claim 1, wherein the second feature quantity includes a time domain feature, a derivative signal feature and a frequency domain feature.
3. The method of claim 2, wherein the derivative signal characteristic comprises a second order magnitude of a peak of the pulse wave signal.
4. The method of correcting a blood pressure measurement based on temperature of claim 3, wherein the formulaic relationship comprises:
the first characteristic quantity is PTT, PTT is the conduction time of a pulse wave from the heart to the finger, delta BP is the systolic pressure, d is the distance from the heart to the finger, g is the gravity acceleration, h is the distance from the heart to the finger tip, and rho is the concentration of blood;
if the blood pressure compensation amount is C × Dm, the blood pressure formula containing the blood pressure compensation amount is:
the second characteristic quantity is Dm, the Dm is a second-order amplitude value of the top end point of the pulse wave signal, C is a temperature compensation constant of systolic pressure, and C is obtained through calculation.
5. The method for correcting a blood pressure measurement based on temperature of claim 4, wherein the step of calculating the temperature compensation constant comprises:
measuring a plurality of groups of actual blood pressure values, substituting the second-order amplitude values of the top end points of the pulse wave signals during each measurement, and calculating to obtain a plurality of temperature compensation constants;
and calculating the average value of the plurality of temperature compensation constants, wherein the average value is the temperature compensation constant.
6. A system for correcting a blood pressure measurement based on temperature, comprising:
the derivation module is used for deriving and determining a formula relation between the blood pressure and the first characteristic quantity of the pulse wave signal per se through a formula;
the processing module is used for calculating a theoretical blood pressure value according to a formula, measuring an actual blood pressure value at different temperatures, and determining a blood pressure compensation quantity based on temperature by comparing the actual blood pressure value with the theoretical blood pressure value, wherein the compensation quantity contains second characteristic quantities of the blood pressure and the pulse wave signal;
and the correction module is used for correcting the measured blood pressure value by using the blood pressure compensation quantity.
7. The system for correcting blood pressure measurements based on temperature of claim 6, wherein the second characteristic measure includes a time domain characteristic, a derivative signal characteristic, and a frequency domain characteristic.
8. The system for correcting blood pressure measurements based on temperature of claim 7, wherein the derivative signal characteristic comprises a second order magnitude of a peak of the pulse wave signal.
9. The system for correcting blood pressure measurements based on temperature according to claim 8, wherein said formulaic relationship comprises:
the first characteristic quantity is PTT, PTT is the conduction time of the pulse wave from the heart to the finger, delta BP is the systolic pressure, d is the distance from the heart to the finger, g is the gravity acceleration, h is the distance from the heart to the finger tip, rho is the concentration of blood, and PTT is the conduction time of the pulse wave from the heart to the finger;
if the blood pressure compensation amount is C × Dm, the blood pressure formula containing the blood pressure compensation amount is:
the second characteristic quantity is Dm, the Dm is a second-order amplitude value of the top end point of the pulse wave signal, C is a temperature compensation constant of systolic pressure, and C is obtained through calculation.
10. The system according to claim 9, wherein the processing module is further configured to measure a plurality of sets of actual blood pressure values, and substitute the second-order amplitude value of the top point of the pulse wave signal for each measurement to obtain a plurality of temperature compensation constants by calculation; and calculating the average value of the plurality of temperature compensation constants, wherein the average value is the temperature compensation constant.
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Cited By (7)
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| CN107928637A (en) * | 2017-12-12 | 2018-04-20 | 吉林大学 | A kind of pulse manifestation testing system based on array of pressure sensors |
| CN107970028A (en) * | 2017-12-12 | 2018-05-01 | 吉林大学 | A kind of novel digital type pulse-taking instrument |
| US20180177413A1 (en) * | 2016-12-27 | 2018-06-28 | Samsung Electronics Co., Ltd. | Touch-type blood pressure measurement apparatus and method |
| CN112040849A (en) * | 2018-04-13 | 2020-12-04 | 深圳市长桑技术有限公司 | System and method for determining blood pressure of a subject |
| CN112515645A (en) * | 2021-02-07 | 2021-03-19 | 江西科莱富健康科技有限公司 | Blood pressure measurement data processing method and system and computer equipment |
| CN112826453A (en) * | 2019-11-05 | 2021-05-25 | 深圳市大富智慧健康科技有限公司 | Blood pressure pulse condition monitoring method and blood pressure pulse condition monitoring system |
| CN117045217A (en) * | 2023-10-13 | 2023-11-14 | 深圳市奋达智能技术有限公司 | Cuff-free blood pressure measurement method and related equipment thereof |
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| US20180177413A1 (en) * | 2016-12-27 | 2018-06-28 | Samsung Electronics Co., Ltd. | Touch-type blood pressure measurement apparatus and method |
| US10813561B2 (en) * | 2016-12-27 | 2020-10-27 | Samsung Electronics Co., Ltd. | Touch-type blood pressure measurement apparatus and method |
| CN107928637A (en) * | 2017-12-12 | 2018-04-20 | 吉林大学 | A kind of pulse manifestation testing system based on array of pressure sensors |
| CN107970028A (en) * | 2017-12-12 | 2018-05-01 | 吉林大学 | A kind of novel digital type pulse-taking instrument |
| CN112040849A (en) * | 2018-04-13 | 2020-12-04 | 深圳市长桑技术有限公司 | System and method for determining blood pressure of a subject |
| CN112040849B (en) * | 2018-04-13 | 2024-01-02 | 深圳市长桑技术有限公司 | System and method for determining blood pressure of a subject |
| CN112826453A (en) * | 2019-11-05 | 2021-05-25 | 深圳市大富智慧健康科技有限公司 | Blood pressure pulse condition monitoring method and blood pressure pulse condition monitoring system |
| CN112515645A (en) * | 2021-02-07 | 2021-03-19 | 江西科莱富健康科技有限公司 | Blood pressure measurement data processing method and system and computer equipment |
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