CN203846030U - System for safely and efficiently preparing collagens through one-step method - Google Patents
System for safely and efficiently preparing collagens through one-step method Download PDFInfo
- Publication number
- CN203846030U CN203846030U CN201420173842.2U CN201420173842U CN203846030U CN 203846030 U CN203846030 U CN 203846030U CN 201420173842 U CN201420173842 U CN 201420173842U CN 203846030 U CN203846030 U CN 203846030U
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- China
- Prior art keywords
- tank
- ion exchange
- extractor
- exchange column
- spray
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- Expired - Lifetime
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- 102000008186 Collagen Human genes 0.000 title claims abstract description 28
- 108010035532 Collagen Proteins 0.000 title claims abstract description 28
- 238000000034 method Methods 0.000 title claims abstract description 12
- 229920001436 collagen Polymers 0.000 title abstract description 7
- 238000005342 ion exchange Methods 0.000 claims abstract description 14
- 238000001694 spray drying Methods 0.000 claims abstract description 9
- 238000010306 acid treatment Methods 0.000 claims abstract description 8
- 230000002255 enzymatic effect Effects 0.000 claims description 10
- 230000001954 sterilising effect Effects 0.000 claims description 8
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 6
- 230000008676 import Effects 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
- 230000001105 regulatory effect Effects 0.000 claims description 3
- 238000005265 energy consumption Methods 0.000 abstract description 3
- 241001465754 Metazoa Species 0.000 description 5
- 238000000605 extraction Methods 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000000050 nutritive effect Effects 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000726221 Gemma Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000000774 hypoallergenic effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 150000004965 peroxy acids Chemical class 0.000 description 1
- 230000020978 protein processing Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Landscapes
- Peptides Or Proteins (AREA)
Abstract
The utility model discloses a system for safely and efficiently preparing collagens through a one-step method. The system comprises an acid treatment tank, an extracting tank, a buffer tank, a filter, an ion exchange column, a concentration evaporator, an enzymolysis tank, a sterilizer and a spray drying tower, wherein an outlet of the acid treatment tank is connected with a feeding hole of the extracting tank; the extracting tank is connected with the buffer tank; a discharge opening of the buffer tank is connected to a feeding hole of the filter; a discharge opening of the filter is connected with an inlet of the ion exchange column; an outlet of the ion exchange column is connected with the concentration evaporator; a discharge opening of the concentration evaporator is connected with a feeding hole of the enzymolysis tank, and a discharge opening of the enzymolysis tank is connected with an inlet of the sterilizer; the sterilizer is connected with the spray drying tower. According to the system, stable product quality can be guaranteed, the product purity and safety are improved, energy consumption in the processing process is reduced, and the processing cost is reduced.
Description
Technical field
This practicality relates to collagen protein processing technique field, is specifically related to the safe and efficient system of preparing collagen protein of single stage method.
Background technology
Collagen protein is the main component in animal connective tissue, is also that Mammals in-vivo content is maximum, the widest functional protein that distributes, and accounts for 25%～30% of total protein.With the transmission of the formation of organizing, maturation, iuntercellular information, and joint lubrication, wound healing, calcification, blood coagulation and aging etc. have close relationship.Collagen protein is also one of critical starting material of tool of biotech industry, in all extensive application such as medical material, makeup, foodstuffs industry.What nowadays use is women's skin care products and cosmetics the most widely.
Due to the difference of the aspects such as amino acid composition and degree of crosslinking, make especially its processing waste-skin of aquatic animal, bone, in squama, contained abundant collagen protein has the unexistent advantage of a lot of livestock collagen proteins, as certain gelation, the dispersiveness of height, low viscosity, water-absorbent, retentiveness and emulsifying property etc., it is found that in addition the collagen protein that derives from marine animal is obviously better than the collagen protein of terrestrial animal in some respects, such as thering is low antigenicity, hypoallergenic, denaturation temperature is low, solubility is high, easily by characteristics such as protease hydrolysiss.Therefore aquatic collagen protein may progressively substitute terrestrial animal collagen protein.
In fish-skin, contain abundant collagen protein, become the main raw material that extracts collagen protein.The weak point of the system of processing of the collagen of fish skin generally using at present, is: 1) stability of quality product is difficult to ensure; 2) life cycle of the product is long, and energy consumption cost is high; 3) security of product can not be guaranteed.
Utility model content
For overcoming the defect of prior art, being of this practicality provides a kind of single stage method the safe and efficient system of preparing collagen protein, when ensureing quality product stable, improves product purity and security, and reduces the energy consumption in the course of processing, cuts down finished cost.
The technical scheme that this practicality adopts is for achieving the above object as follows:
The safe and efficient system of preparing collagen protein of single stage method, its bag acid treatment pond, extractor, surge tank, strainer, ion exchange column, concentration evaporator, enzymatic vessel, Sterilizers, spray-drying tower; The outlet in described acid treatment pond is connected with the opening for feed of extractor, extractor connects surge tank, the discharge port of surge tank is connected to the opening for feed of strainer, the discharge port of strainer is connected with the import of ion exchange column, the outlet of ion exchange column connects concentration evaporator, the import that the discharge port of concentration evaporator is connected with enzymatic vessel opening for feed, the discharge port of enzymatic vessel connects Sterilizers, Sterilizers is connected with spray-drying tower.
The utility model can be realized by following scheme:
As the preferred scheme of one of the present utility model, described extractor is provided with temperature regulating device.
As the preferred scheme of one of the present utility model,, described strainer is kieselguhr filter or activated charcoal filter.
As the preferred scheme of one of the present utility model, described Sterilizers is for exceeding high-temperature short-time sterilization device, and it provides the high pressure steam of 150-165 DEG C in the time of sterilizing.
As the preferred scheme of one of the present utility model, described moisture eliminator is spray-dryer, the drying tower inlet temperature 140-180 DEG C of described spray-dryer, air outlet temperature 70-85 DEG C.Employing spray-dryer can not only reach the object of drying products moisture, has also ensured the indices stability of product.
Compared to existing technology, the beneficial effects of the utility model are:
1. can effectively ensure extraction yield and quality product by system of the present utility model, obtain stable, the purity high product of quality;
2. system of the present utility model can effectively be taken out the fishy smell in fish-skin, has obtained the collagen product of colorless and odorless, has improved the local flavor of collagen protein;
3. system of the present utility model, by after ion exchange treatment, has been removed heavy metal and the nonmetallic ion that in raw material, may contain, the security that has improved product;
4. a nutritive ingredient that practical system has been preserved collagen greatly, has prevented the secondary pollution of collagen protein effectively, has greatly extended the quality guaranteed period of product.
Below in conjunction with concrete embodiment, this practicality is described in further detail.
Brief description of the drawings
Fig. 1 is the safe and efficient system architecture schematic diagram of preparing collagen protein of single stage method described in the utility model.
Embodiment
As shown in Figure 1, the safe and efficient system of preparing collagen protein of single stage method described in the utility model, its bag acid treatment pond 1, extractor 2, surge tank 3, strainer 4, ion exchange column 5, concentration evaporator 6, enzymatic vessel 7, Sterilizers 8, spray-drying tower 9; The outlet in described acid treatment pond 1 is connected with the opening for feed of extractor 2, extractor 2 connects surge tank 3, the discharge port of surge tank 3 is connected to the opening for feed of strainer 4, the discharge port of strainer 4 is connected with the import of ion exchange column 5, the outlet of ion exchange column 5 connects concentration evaporator 6, the import that the discharge port of concentration evaporator 6 is connected with enzymatic vessel 7 opening for feeds, the discharge port of enzymatic vessel 7 connects Sterilizers 8, Sterilizers 8 is connected with spray-drying tower 9; Described extractor is provided with temperature regulating device, and the temperature of extractor can be set.The process that adopts the utility model to prepare collagen protein is: raw material is transferred in extractor 2 and is extracted after peracid treatment pond place 1 manages, liquid after extraction is transferred in surge tank 3, solid substance after extraction continues to extract for the second time in extractor 1, and the temperature of extractor 1 is increased temperature to 10 DEG C on the basis of extracting for the first time temperature; Carry secondary raffinate and proceed in extractor 1, repeat to extract four times; Extracting solution in surge tank 2 obtains product through strainer 4, ion exchange column 5, concentration evaporator 6, enzymatic vessel 7, Sterilizers 8, spray-drying tower 9 after processing successively.
The utility model can be realized by following scheme:
As the preferred scheme of one of the present utility model, described strainer 3 is kieselguhr filter or activated charcoal filter.
As the preferred scheme of one of the present utility model, described Sterilizers 7 is for exceeding high-temperature short-time sterilization device, and it provides the high pressure steam of 150-165 DEG C in the time of sterilizing.Employing exceedes that high-temperature short-time sterilization device is instantaneous under the high pressure steam of 150-165 DEG C completes sterilizing, can cause that microorganism that material is corrupt and rotten and gemma and enzyme thoroughly kill, preserve greatly the nutritive ingredient of collagen, effectively prevent the secondary pollution of collagen protein, greatly extended the quality guaranteed period of product.
As the preferred scheme of one of the present utility model, described moisture eliminator 8 is spray-dryer, the drying tower inlet temperature 140-180 DEG C of described spray-dryer, air outlet temperature 70-85 DEG C.Employing spray-dryer can not only reach the object of drying products moisture, has also ensured the indices stability of product.
Above-mentioned embodiment is only this practical preferred implementation; the scope that can not limit with this this practicality protection, the variation of any unsubstantiality that those skilled in the art does on the basis of this practicality and replacement all belong to this practical scope required for protection.
Claims (5)
1. the safe and efficient system of preparing collagen protein of single stage method, is characterized in that, its bag acid treatment pond, extractor, surge tank, strainer, ion exchange column, concentration evaporator, enzymatic vessel, Sterilizers, spray-drying tower; The outlet in described acid treatment pond is connected with the opening for feed of extractor, extractor connects surge tank, the discharge port of surge tank is connected to the opening for feed of strainer, the discharge port of strainer is connected with the import of ion exchange column, the outlet of ion exchange column connects concentration evaporator, the import that the discharge port of concentration evaporator is connected with enzymatic vessel opening for feed, the discharge port of enzymatic vessel connects Sterilizers, Sterilizers is connected with spray-drying tower.
2. system according to claim 1, is characterized in that, described extractor is provided with temperature regulating device.
3. system according to claim 1, is characterized in that, described strainer is kieselguhr filter or activated charcoal filter.
4. system according to claim 1, is characterized in that: described Sterilizers is for exceeding high-temperature short-time sterilization device, and it provides the high pressure steam of 150-165 DEG C in the time of sterilizing.
5. system according to claim 1, is characterized in that: described moisture eliminator is spray-dryer, the drying tower inlet temperature 140-180 DEG C of described spray-dryer, air outlet temperature 70-85 DEG C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420173842.2U CN203846030U (en) | 2014-04-10 | 2014-04-10 | System for safely and efficiently preparing collagens through one-step method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420173842.2U CN203846030U (en) | 2014-04-10 | 2014-04-10 | System for safely and efficiently preparing collagens through one-step method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203846030U true CN203846030U (en) | 2014-09-24 |
Family
ID=51559068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420173842.2U Expired - Lifetime CN203846030U (en) | 2014-04-10 | 2014-04-10 | System for safely and efficiently preparing collagens through one-step method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203846030U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104479995A (en) * | 2014-12-30 | 2015-04-01 | 广州康洛信生物科技有限公司 | Sheepskin collagen extraction system and method |
-
2014
- 2014-04-10 CN CN201420173842.2U patent/CN203846030U/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104479995A (en) * | 2014-12-30 | 2015-04-01 | 广州康洛信生物科技有限公司 | Sheepskin collagen extraction system and method |
| CN104479995B (en) * | 2014-12-30 | 2016-08-24 | 广州康洛信生物科技有限公司 | Corii Caprae seu Ovis collagen protein extraction system and extracting method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190429 Address after: 528300 Unit 1306, Building 4, Xinbao Plaza, 46 Tianhong Road, Foshan New Town, Lecong Town, Shunde District, Foshan City, Guangdong Province Patentee after: Kangluoxin (Guangdong) Biotechnology Co.,Ltd. Address before: 510000 Room 59A, Area B, 3rd Floor, East Station Complex Building, No. 1 East Station Road, Tianhe District, Guangzhou City, Guangdong Province Patentee before: GUANGZHOU COLLOZINE BIOTECHNOLOGY Co.,Ltd. |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20140924 |