CN203764243U - Integrated continuous molding device of crystal gel medium - Google Patents
Integrated continuous molding device of crystal gel medium Download PDFInfo
- Publication number
- CN203764243U CN203764243U CN201420183324.9U CN201420183324U CN203764243U CN 203764243 U CN203764243 U CN 203764243U CN 201420183324 U CN201420183324 U CN 201420183324U CN 203764243 U CN203764243 U CN 203764243U
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- China
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- control circuit
- peristaltic pump
- collecting tank
- gel medium
- sample
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Abstract
The utility model relates to an integrated continuous molding device of a crystal gel medium. The device comprises a sample jar group, a peristaltic pump group, a microchannel reactor, a collecting jar, a stirrer and a controller, wherein the sample tank group comprises a plurality of sample jars in which temperature sensors are arranged; the peristaltic pump group comprises at least two peristaltic pumps which are connected with the sample jars through pipelines; the microchannel reactor is connected with the peristaltic pumps through pump pipes; the collecting jar is connected with the microchannel reactor through the pipeline and positioned in a constant/low-temperature body; the temperature sensor is arranged in the collecting jar; the stirrer is arranged above the collecting jar and used for stirring a liquid in the collecting jar; the controller comprises a single-chip microcomputer, and a peristaltic pump control circuit, a temperature control circuit and a display control circuit connected with the single-chip microcomputer; the peristaltic pump control circuit is connected with the peristaltic pump group; the temperature control circuit is connected with the temperature sensors in the sample jars and the collecting jar; the display control circuit is connected with a touch display screen. According to the device, the continuous semi-automatic preparation of the crystal gel medium is realized, thereby meeting the requirements of large-scale preparation and industrial applications.
Description
Technical field
The utility model relates to crystal gel medium building mortion, particularly relates to a kind of integrated form crystal gel medium progressive forming device.
Background technology
The micron order of size homogeneous or nano level carrier granular or media particle have important application in many fields such as new medicament screen, biochemical separation, medical science detection, gene therapy, medicine controlled releasings, and demand both domestic and external increased sharply in recent years.But due to the particularity of the micro-nano grain of rice, control and big or small homogeneity problem that particle diameter distributes are the difficult problems that needs solve always.And utilize that microchannel can prepare that monodispersity is good, particle diameter and the controlled crystal gel medium of form be widely used in experiment.But existing making in laboratory crystal gel medium system mainly adopts assembling discrete type, not only operates and there is no systematicness, and operate very inconveniently, can not realize the extensive continuous production of preparing crystal gel medium simultaneously.
Utility model content
The purpose of this utility model is the system of existing making in laboratory crystal gel medium to improve, designing and making goes out an all-in-one-piece microchannel crystal gel medium building mortion, the continuous semi-automatic system of realizing crystal gel medium is standby, meets the demand of extensive preparation and commercial Application.
For reaching above-mentioned purpose, the utility model provides a kind of integrated form crystal gel medium progressive forming device, comprising:
Sample jar group, comprises a plurality of sample jars, and splendid attire testing liquid is provided with temperature sensor in sample jar;
Peristaltic pump group, comprises at least two peristaltic pumps, and peristaltic pump is connected with sample jar by pipeline;
Micro passage reaction, is connected with peristaltic pump by pump line;
Collecting tank, is connected with micro passage reaction by pipeline, and this collecting tank is placed in permanent cryotron, in this collecting tank, is provided with temperature sensor;
Agitator, is arranged on this collecting tank top, and the liquid in collecting tank is stirred;
Controller, comprise single-chip microcomputer, and the peristaltic pump control circuit, temperature control circuit and the display control circuit that are connected with this single-chip microcomputer, peristaltic pump control circuit is connected with peristaltic pump group, temperature control circuit is connected with the temperature sensor in collecting tank with sample jar, and display control circuit connects a touch display screen.
In device described in the utility model, this micro passage reaction comprises upper cover plate, encapsulation dividing plate and reaction plate, and wherein upper cover plate and reaction plate are 304 corrosion resistant plates, and encapsulation dividing plate is inert polymer pp plate.
In device described in the utility model, described permanent cryotron is the alcohol bucket of filling alcohol, and this alcohol bucket is placed in the foam bucket that dry ice is housed.
In device described in the utility model, described peristaltic pump is provided with damping device.
The beneficial effects of the utility model are: this device carries out existing discreteness experimental facilities integrated and introduces single-chip computer control system, adopting peristaltic pump to realize continuous liquid carries, realized the automatic control of crystal gel medium progressive forming and experimentation, can meet well crystal gel medium and prepare on a large scale, and provide possibility for the demand of commercial Application.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the utility model is described in further detail, in accompanying drawing:
Fig. 1 is the structural representation of the utility model embodiment integrated form crystal gel medium progressive forming device.
The specific embodiment
For making that architectural feature of the present utility model and the effect reached are had a better understanding and awareness, in order to preferred embodiment and accompanying drawing, coordinate detailed explanation, be described as follows:
The integrated form crystal gel medium progressive forming device of the utility model embodiment carries out the experimental provision of existing discretization integrated, and realizes the semi-automatic progressive forming of crystal gel medium.
Integrated form crystal gel medium progressive forming device of the present utility model comprises:
Sample jar group 10, comprises a plurality of sample jars, and splendid attire testing liquid (as water, oil phase, monomer solution and catalyst), is provided with temperature sensor 70 in sample jar; Peristaltic pump group 20, comprises at least two peristaltic pumps, and peristaltic pump is connected with sample jar by pipeline; Sample jar group 10 and peristaltic pump group 20 arrange the number of sample jar and the number of peristaltic pump as required.Peristaltic pump mainly comprises the fixtures such as pump line, Peristaltic pump head, stepper motor, stepper motor driver, shaft coupling, control circuit and pump head, stepper motor gripper shoe.In an embodiment of the present utility model, also damping device can be set on peristaltic pump, to alleviate the vibrations of motor.Sample jar group 10 and peristaltic pump group 20 can provide stable, pulse free, flow mobile phase accurately for microchannel.
Micro passage reaction 30, is connected with peristaltic pump by pump line; Reaction plate is provided with a plurality of plates and carries microchannel.Micro passage reaction 30 of the present utility model comprises sealing plate, cover plate and substrate, and wherein upper cover plate and reaction plate can be selected 304 corrosion resistant plates, and encapsulation dividing plate is selected inert polymer pp plate.On reaction plate, process " ten " word cross hedge microchannel, T-shape microchannel or " Y " type microchannel that can carry out fluid focus, wherein cross section, microchannel is rectangle.Upper cover plate, encapsulation dividing plate are added a cover and on substrate, formed plate and carry MCA, this plate carries MCA and utilizes Fluid focus technology to become to drip, the droplet size homogeneous forming, brilliant glue microballoon through crystallization pore and polymerisation formation, its narrow diameter distribution, particle size regulates by the mobile of profit phase, has realized the controlled preparation of brilliant glue microsphere particle.
Collecting tank 40, is connected with micro passage reaction 30 by pipeline, and this collecting tank 40 is placed in permanent cryotron, in this collecting tank 40, is provided with temperature sensor 70; The object that collecting tank is placed in to permanent cryotron is to guarantee that the fluid temperature of collecting tank is at-19 ℃.In order to achieve this end, an embodiment of the present utility model adopts physical method, the can body of the good collecting tank of heat conductivility is immersed in the alcohol bucket of filling alcohol, again alcohol bucket is placed in the bubble chamber that dry ice is housed, by dry ice, volatilize to absorb heat and reduce the alcohol temperature in alcohol bucket, logical heat transfer lowers the fluid temperature in collecting tank and remains on-19 ℃ simultaneously.
Agitator 50, is arranged on this collecting tank 40 tops, and the liquid in collecting tank 40 is stirred; By independent agitator, the liquid of collecting tank the inside is stirred, prevent that the crystal gel medium of making is bonded together in collecting tank, and stir and can make crystal gel medium surface more fluffy, shape is more regular.
Controller 60, comprise single-chip microcomputer, and the peristaltic pump control circuit, temperature control circuit and the display control circuit that are connected with this single-chip microcomputer, peristaltic pump control circuit is connected with peristaltic pump group 20, temperature control circuit is connected with the temperature sensor 70 in collecting tank with sample jar, and display control circuit connects a touch display screen.Control and temperature detection for peristaltic pump all can be completed by same single-chip microcomputer, select to adopt STC12C5A60S single-chip microcomputer in the present invention.
Peristaltic pump control circuit mainly comprises stepper motor driver module, step motor control module, man-machine interface and power supply; Stepper motor driver module is mainly realized the control requirement of single-chip microcomputer to stepper motor, and step motor control module mainly completes parameter input, parameter display and the functions such as control to drive part; The power supply of stepper motor is provided by stepper motor driver, and the power supply of stepper motor driver is provided after transformation, rectification, voltage stabilizing by external power source.
The technological process that this integrated form crystal gel medium building mortion is made according to brilliant glue microballoon realizes corresponding function, by liquid crystal display touch screen, realize man-machine exchange simultaneously, use liquid crystal touch screen interface to realize parameter setting, function setting, Data Detection, the work such as brake hard, thus realize the semi-automatic and intelligent of whole building mortion.
Temperature sensor detects the temperature for the treatment of liquid in pumping liquid and collecting tank in sample jar in real time, because temperature range is between-100 ℃ to 50 ℃, temperature sensor can adopt PT100 thermocouple, and the temperature range of this thermocouple is between-200 ℃ to 500 ℃, satisfied temperature designing requirement.
During the integrated form crystal gel medium progressive forming device busy of the utility model embodiment, first peristaltic pump pump line is connected with microchannel, then opening device power supply, shows that screen display enters working interface.Then temperature sensor (as thermocouple) is put in the stainless steel collecting tank that liquid is housed, measures the fluid temperature in stainless steel collecting tank, temperature value can be presented on screen.Can be by opening the polytetrafluoroethylene (PTFE) stopper (in permanent cryotron, filling foam is used for isolating and insulation) on permanent cryotron, filling dry ice regulates temperature.Another temperature sensor (as thermocouple) is put into sample jar and measure testing liquid temperature, temperature value also can be presented on screen.By touch display screen, set speed and the parameter such as turn to, open two peristaltic pumps, carry out the granulation process of crystal gel medium, in granulation process, will use agitator to stir liquid.In granulation process, the utility model can carry out the monitoring and controlling on micro-scale to micro liquid or sample by the microchannel of micro passage reaction.When granulation is complete, two peristaltic pumps are stopped, microchannel is removed, take out the stainless steel cask in stainless steel collecting tank, carry out low temperature insulation.It is standby that the utility model can be realized the continuous semi-automatic system of crystal gel medium, meets the demand of extensive preparation and commercial Application, has important practical significance and wide application prospect.
The utility model, on the basis based on microflow control technique instrument typical structure, in conjunction with the function of fabrication processing and the microchannel granulating system of crystal gel medium, improves the system of existing making in laboratory crystal gel medium.The utility model improved the experiment condition that the crystal gel medium of current domestic discrete type is shaped, and solved the problem of micro-amounts of liquids, stable and uninterrupted pumping, developed the method for large-scale production.
Should be understood that, for those of ordinary skills, can be improved according to the above description or convert, and all these improvement and conversion all should belong to the protection domain of the utility model claims.
Claims (4)
1. an integrated form crystal gel medium progressive forming device, is characterized in that, comprising:
Sample jar group, comprises a plurality of sample jars, and splendid attire testing liquid is provided with temperature sensor in sample jar;
Peristaltic pump group, comprises at least two peristaltic pumps, and peristaltic pump is connected with sample jar by pipeline;
Micro passage reaction, is connected with peristaltic pump by pump line;
Collecting tank, is connected with micro passage reaction by pipeline, and this collecting tank is placed in permanent cryotron, in this collecting tank, is provided with temperature sensor;
Agitator, is arranged on this collecting tank top, and the liquid in collecting tank is stirred;
Controller, comprise single-chip microcomputer, and the peristaltic pump control circuit, temperature control circuit and the display control circuit that are connected with this single-chip microcomputer, peristaltic pump control circuit is connected with peristaltic pump group, temperature control circuit is connected with the temperature sensor in collecting tank with sample jar, and display control circuit connects a touch display screen.
2. device according to claim 1, is characterized in that, this micro passage reaction comprises upper cover plate, encapsulation dividing plate and reaction plate, and wherein upper cover plate and reaction plate are 304 corrosion resistant plates, and encapsulation dividing plate is inert polymer pp plate.
3. device according to claim 1, is characterized in that, described permanent cryotron is the alcohol bucket of filling alcohol, and this alcohol bucket is placed in the foam bucket that dry ice is housed.
4. device according to claim 1, is characterized in that, described peristaltic pump is provided with damping device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420183324.9U CN203764243U (en) | 2014-04-16 | 2014-04-16 | Integrated continuous molding device of crystal gel medium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420183324.9U CN203764243U (en) | 2014-04-16 | 2014-04-16 | Integrated continuous molding device of crystal gel medium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203764243U true CN203764243U (en) | 2014-08-13 |
Family
ID=51281491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420183324.9U Withdrawn - After Issue CN203764243U (en) | 2014-04-16 | 2014-04-16 | Integrated continuous molding device of crystal gel medium |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203764243U (en) |
-
2014
- 2014-04-16 CN CN201420183324.9U patent/CN203764243U/en not_active Withdrawn - After Issue
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20140813 Effective date of abandoning: 20160203 |
|
| C25 | Abandonment of patent right or utility model to avoid double patenting |