CN203704484U - Low-temperature storage device operating in electromagnetic freezing mode - Google Patents
Low-temperature storage device operating in electromagnetic freezing mode Download PDFInfo
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- CN203704484U CN203704484U CN201420055482.6U CN201420055482U CN203704484U CN 203704484 U CN203704484 U CN 203704484U CN 201420055482 U CN201420055482 U CN 201420055482U CN 203704484 U CN203704484 U CN 203704484U
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- cooling bench
- low temperature
- storage device
- temperature storage
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Abstract
The utility model discloses a low-temperature storage device operating in an electromagnetic freezing mode. The device comprises a low-temperature temperature-constant groove, Helmholtz coils, a voltage-stabilized power source and a cooling table, wherein the low-temperature temperature-constant groove is connected with the cooling table through a circulating pump, the Helmholtz coils are distributed on the two sides of the cooling table, the voltage-stabilized power source is connected with the Helmholtz coils, the cooling table is provided with a groove, and a penicillin bottle containing drugs or living organisms is placed in the groove of the cooling table. The drugs or the living organisms are stored at a low temperature in the electromagnetic freezing mode, and integrity and timeliness of the stored articles are guaranteed.
Description
Technical field
The utility model relates to a kind of low temperature storage device of applying electromagnetism freezing.
Background technology
Modern medicine is thermal sensitivity medicine mostly, to temperature (being mainly high temperature) than more sensitive medicine.In the time of production thermal sensitivity medicine, for preventing that excess Temperature from making medicine sex change, affect the quality of product, will carry out low temperature preservation to medicine.And many organisms also need to preserve at low temperatures its activity.How farthest avoiding the damage in freezing and rewarming process is the target that people pursued for a long time.Low temperature Techniques of preserving mainly contains two kinds of methods at present, is respectively slow freezing method and vitrification.Slow freezing method rate of temperature fall is slow, and adds a certain amount of cryoprotective agent.In this way not only can cause the formation of the larger ice crystal that destroys biological cell structure, but also can produce toxicity to cell.Have a strong impact on and be saved the integrality of organism and ageing.Although the cellular damage that vitrification can avoid ice crystal to cause by add the method for cryoprotective agent under snap frozen largely; but cryoprotective agent has certain damaging, and real process can not improve too fastly by cooling velocity.
Utility model content
The utility model is in order to address the above problem; a kind of low temperature storage device of applying electromagnetism freezing has been proposed; this device makes up the at present weak point of main Cryopreservation by electromagnetic field freezing, can be good to carrying out low temperature preservation containing sucrose medicine or the organism using sucrose as cryoprotective agent.
To achieve these goals, the utility model adopts following technical scheme:
Apply a low temperature storage device for electromagnetism freezing, comprise low temperature thermostat bath, Helmholtz coil, voltage-stabilized power supply and cooling bench; Wherein, low temperature thermostat bath connects cooling bench by circulating pump, and Helmholtz coil is laid in both sides on cooling bench, and voltage-stabilized power supply connects Helmholtz coil, and described cooling bench is provided with groove, and the cillin bottle that medicine or organism are housed is positioned in the groove of cooling bench.
Described cooling bench inside is provided with the refrigerating liquid runner of bending, and cooling bench is provided with refrigerating liquid entrance and exit, and refrigerating liquid runner communicates with refrigerating liquid entrance and exit.
Described cooling bench is that the aluminium alloy of thermal conductivity factor 228W/ (mK) is made.
Operation principle of the present utility model is: this method is applied to containing the low temperature of sucrose medicine or the organism using sucrose as cryoprotective agent and preserves; in the time that externally-applied magnetic field acts on sucrose solution; hydrone and sucrose molecule all can produce swing; because the polarity of hydrone is greater than sucrose molecule, so the hunting frequency of hydrone is greater than the hunting frequency of sucrose molecule.Will cause like this hydrogen bond rupture between sucrose molecule and hydrone, so sucrose solution physical property can be subject to certain impact, the effect of preserving to reach low temperature.
The beneficial effects of the utility model are:
1, utilize electromagnetism freezing to carry out low temperature and preserve medicine or organism, ensured to be saved the integrality of article and ageing;
2, rate of temperature fall fast, without adding protective agent, improve quality of protection;
3, avoid the generation of large ice crystal, avoid the harm of cryoprotective agent to medicine/organism.
Brief description of the drawings
Fig. 1 is structural representation of the present utility model;
Fig. 2 is cooling bench cross-section front view of the present utility model;
Fig. 3 is cooling bench cross sectional side view of the present utility model;
Fig. 4 is the cooling chart of 8% sucrose solution under different magnetic field intensity.
Wherein, 1, low temperature thermostat bath; 2, Helmholtz coil; 3, cillin bottle; 4, voltage-stabilized power supply; 5, cooling bench; 6, refrigerating liquid entrance; 7, refrigerating liquid outlet; 8, groove; 9, runner.
Detailed description of the invention:
Below in conjunction with accompanying drawing and embodiment, the utility model is described in further detail.
As shown in Figure 1, a kind of low temperature storage device of applying electromagnetism freezing, comprises low temperature thermostat bath 1, Helmholtz coil 2, voltage-stabilized power supply 4 and cooling bench 5; Wherein, low temperature thermostat bath 1 connects cooling bench 5 by circulating pump, Helmholtz coil 2 is laid in both sides on cooling bench 5, voltage-stabilized power supply 4 connects Helmholtz coil 2, the aluminium alloy that cooling bench 5 is thermal conductivity factor 228W/ (mK) is made, cooling bench 5 is provided with groove 8, and the cillin bottle 3 that medicine or organism are housed is positioned in the groove 8 of cooling bench 5.
As shown in Figure 2 and Figure 3, cooling bench 5 inside are provided with the refrigerating liquid runner 9 of bending, and cooling bench is provided with refrigerating liquid entrance 6 and refrigerating liquid outlet 7, and refrigerating liquid runner 9 communicates with refrigerating liquid entrance 6 and refrigerating liquid outlet 7.
A method of operating that adopts above-mentioned low temperature storage device, specifically comprises the following steps:
(1) utilize low temperature thermostat bath 1 that refrigerating liquid is cooled to subzero 20 ° of C;
(2) by circulating pump, refrigerating medium is sent in cooling bench 5, made cooling bench 5 upper surfaces keep the constant temperature of-15 DEG C, the cillin bottle 3 that medicine is housed is placed on to cooling bench 5 upper surface groove 8 places;
(3) voltage-stabilized power supply 4 is powered to Helmholtz coil 2, around being placed with the cooling bench 5 of cillin bottle 3, applies magnetic field, and magnetic field intensity, between 5-300G, is direct current or AC magnetic field, and magnetic field intensity is corresponding with the voltage of voltage-stabilized power supply 4;
(4) ensure that externally-applied magnetic field effect and cooling simultaneously beginning of medicine carry out, and continuingly act on medicine.
This method is applied to containing the low temperature of sucrose medicine or the organism using sucrose as cryoprotective agent and preserves; in the time that externally-applied magnetic field acts on sucrose solution; hydrone and sucrose molecule all can produce swing; because the polarity of hydrone is greater than sucrose molecule, so the hunting frequency of hydrone is greater than the hunting frequency of sucrose molecule.Will cause like this hydrogen bond rupture between sucrose molecule and hydrone, so sucrose solution physical property can be subject to certain impact, the effect of preserving to reach low temperature.
As shown in Figure 4,8% sucrose solution is tested as experiment sample, and obtained the cooling curve at place of center of a sample by data collecting instrument.The effect in magnetic field increases the degree of supercooling of sucrose solution, that is to say under the effect in magnetic field, the stability of the sucrose solution of supercooled state increases, the energy exchange in temperature decline process has been offset in the enhancing of intermolecular energy effectively, and the sucrose solution of supercooled state can be preserved at lower temperature.And the existence of free molecular flow and little molecular cluster makes the crystalline core size of crystallization process not reach critical radius, thereby suppress crystallization process.The increase of degree of supercooling simultaneously causes supercooled state time lengthening, thereby water temperature uniformity is increased, and has postponed nucleation time, once nucleus forms on the other hand, can induce whole solution to form rapidly a large amount of nucleus, crystallization process completes rapidly, and the crystalline size of generation reduces greatly.
By reference to the accompanying drawings detailed description of the invention of the present utility model is described although above-mentioned; but the not restriction to the utility model protection domain; one of ordinary skill in the art should be understood that; on the basis of the technical solution of the utility model, those skilled in the art do not need to pay various amendments that creative work can make or distortion still in protection domain of the present utility model.
Claims (3)
1. a low temperature storage device of applying electromagnetism freezing, is characterized in that: a kind of low temperature storage device of applying electromagnetism freezing, comprises low temperature thermostat bath, Helmholtz coil, voltage-stabilized power supply and cooling bench; Wherein, low temperature thermostat bath connects cooling bench by circulating pump, and Helmholtz coil is laid in both sides on cooling bench, and voltage-stabilized power supply connects Helmholtz coil, and described cooling bench is provided with groove, and the cillin bottle that medicine or organism are housed is positioned in the groove of cooling bench.
2. a kind of low temperature storage device of applying electromagnetism freezing as claimed in claim 1, is characterized in that: described cooling bench inside is provided with the refrigerating liquid runner of bending, and cooling bench is provided with refrigerating liquid entrance and exit, and refrigerating liquid runner communicates with refrigerating liquid entrance and exit.
3. a kind of low temperature storage device of applying electromagnetism freezing as claimed in claim 1, is characterized in that: described cooling bench is that the aluminium alloy of thermal conductivity factor 228W/ (mK) is made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420055482.6U CN203704484U (en) | 2014-01-28 | 2014-01-28 | Low-temperature storage device operating in electromagnetic freezing mode |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420055482.6U CN203704484U (en) | 2014-01-28 | 2014-01-28 | Low-temperature storage device operating in electromagnetic freezing mode |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203704484U true CN203704484U (en) | 2014-07-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420055482.6U Expired - Fee Related CN203704484U (en) | 2014-01-28 | 2014-01-28 | Low-temperature storage device operating in electromagnetic freezing mode |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203704484U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103759483A (en) * | 2014-01-28 | 2014-04-30 | 山东大学 | Low temperature preservation device with electromagnetic freezing method applied, and operation method of low temperature preservation device |
-
2014
- 2014-01-28 CN CN201420055482.6U patent/CN203704484U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103759483A (en) * | 2014-01-28 | 2014-04-30 | 山东大学 | Low temperature preservation device with electromagnetic freezing method applied, and operation method of low temperature preservation device |
| CN103759483B (en) * | 2014-01-28 | 2016-07-06 | 山东大学 | A kind of low temperature storage device applying electromagnetism freezing method and operational approach thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140709 Termination date: 20150128 |
|
| EXPY | Termination of patent right or utility model |