CN203663854U - Novel microfluidic chip - Google Patents

Novel microfluidic chip Download PDF

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Publication number
CN203663854U
CN203663854U CN201320387374.4U CN201320387374U CN203663854U CN 203663854 U CN203663854 U CN 203663854U CN 201320387374 U CN201320387374 U CN 201320387374U CN 203663854 U CN203663854 U CN 203663854U
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China
Prior art keywords
layer
micro
chip
production
fluidic chip
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Expired - Fee Related
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CN201320387374.4U
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Chinese (zh)
Inventor
徐小平
高菊逸
杜晶辉
张望
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Shenzhen Hospital University of Hong Kong
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Shenzhen Hospital University of Hong Kong
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Priority to CN201320387374.4U priority Critical patent/CN203663854U/en
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Abstract

The utility model belongs to the field of integrated chips, and provides a novel microfluidic chip. The novel microfluidic chip comprises a first layer, a second layer and a third layer which are overlapped, wherein the second layer adopts a double-side adhesive film and is arranged between the first layer and the third layer and used for bonding and fixing the first layer and the third layer; and a microstructure required by the microfluidic chip is integrated on the double-side adhesive film. The novel microfluidic chip adopts a three-layer space structure, the microstructure is etched on the second layer adopting the double-side adhesion film layer, the operation is simple, and the production efficiency is high. Besides, compared with the conventional chip processing technology, an expensive photoetching machine is not required for chip production, and the production threshold and production cost are reduced greatly; and further, optical radiation is avoided during chip production, chemical reagents such as a photoresist, a developer and the like are not required, environmental protection is achieved, and the body of a laboratorian cannot be harmed.

Description

Novel micro-fluidic chip
Technical field
The utility model belongs to integrated chip technical field, relates in particular to a kind of novel micro-fluidic chip.
Background technology
Micro-fluidic chip is that the basic operation units such as the sample preparation of biological, chemistry, medical analysis process, reaction, separation, detection are integrated on the chip of a micro-meter scale, automatically completes the system-wide a kind of technology of analyzing.Because it is in the great potential in the fields such as biology, chemistry, medical science, develop into the brand-new research field of a biology, chemistry, medical science, fluid, electronics, material, mechanical subject crossing.This micro-fluidic chip technology has the high and low cost of efficiency, easy universal feature.Micro-fluidic chip be by Micrometer-Nanometer Processing Technology by functional modules such as microchannel, Micropump, micro-valve, micro-reservoir, microelectrode, micro-detecting element, window and connectors as integrated circuit, they are integrated on chip material.The making material of chip develops into glass, quartz, organic polymer etc. from silicon chip.Therefore, the process technology of organic polymer material is also at development.The new methods such as fuzz method, pressure sintering, laser ablation method and soft lithographic on the basis of traditional chemical etching, are developed.
The research of micro-fluidic chip type micro-total analysis system is important directions and the forward position of present analysis Instrument Development, traditional micro-fluidic chip is with PDMS(polydimethylsiloxane, dimethyl silicone polymer) be material, the various fine structures of photoetching on PDMS.But the realization of this technology needs expensive litho machine to realize, in the process of photoetching, can produce the radiation of light source, but also need make with photoresist, the chemical reagent such as developer solution, operating procedure very complicated, and laboratory technician's health is had to certain harm, need laboratory to do special setting.
Utility model content
Technical problem to be solved in the utility model is, for a kind of novel micro-fluidic chip, be intended to improve the production efficiency of micro-fluidic chip and reduce its production cost.
The utility model is to realize like this, a kind of novel micro-fluidic chip, it is characterized in that, comprise stacked ground floor, the second layer and the 3rd layer, the described second layer is two-sided adhering film, it is arranged between described ground floor and the 3rd layer, and described ground floor and the 3rd layer are pasted fixing; On described two-sided adhering film, be integrated with the required micro-structural of micro-fluidic chip; Described micro-structural includes the micro-reservoir, connector, window and the microchannel that are connected successively.
Further, described ground floor is made up of any material in PDMS, plastics, glass or cyclic olefine copolymer material.
Further, described ground floor is made up of pmma material.
Further, made by glass or cyclic olefine copolymer material for described the 3rd layer.
Further, described micro-structural comprises microchannel, Micropump, micro-valve, micro-reservoir, microelectrode, micro-detecting element, window and connector.
Further, described micro-structural is etched on the second layer of described chip by laser engraving machine.
Compared with prior art, beneficial effect is the utility model: this novel micro-fluidic chip has adopted the space structure of three layers, and etching micro-structural on the two-sided adhering film of the second layer is simple to operate, production efficiency is high.In addition, with respect to the processing technology of traditional die, the production of this chip need not adopt expensive litho machine, has reduced widely production threshold and production cost; And the production of this chip does not have light radiation, without the chemical reagent such as photoresist, developer solution, comparatively environmental protection, can not endanger laboratory technician's health.
Accompanying drawing explanation
Fig. 1 is the decomposing schematic representation of a kind of novel micro-fluidic chip that provides of the utility model embodiment.
The specific embodiment
In order to make technical problem to be solved in the utility model, technical scheme and beneficial effect clearer, below in conjunction with drawings and Examples, the utility model is further elaborated.Should be appreciated that specific embodiment described herein is only in order to explain the utility model, and be not used in restriction the utility model.
As shown in Figure 1, be a preferred embodiment of the present utility model, a kind of novel micro-fluidic chip, comprise ground floor 1, the second layer 2 and the 3rd layer 3, the second layer 2 is two-sided adhering film, is arranged between ground floor 1 and the 3rd layer 3, and ground floor 1 and the 3rd layer 3 are pasted fixing.On two-sided adhering film, be integrated with the required micro-structural of micro-fluidic chip 21.
Particularly, ground floor 1 can be by PDMS, plastics, glass, lucite, cyclic olefine copolymer COP(cyclo-olefin polymer) or cyclic olefine copolymer COC(cylic olefin copolymer) any material in material makes, be made up for the 3rd layer 3 of glass or cyclic olefine copolymer COC.Micro-structural 21 comprises the functional modules such as Micropump, micro-valve, microelectrode, connector, window, microchannel and micro-detecting element.Described micro-structural 21 is etched on the two-sided adhering film of chip by laser engraving machine.
Micro-fluidic chip of the present utility model has adopted the space structure of three layers, adopts laser engraving machine etching micro-structural 21 on the two-sided adhering film of the second layer 2, simple to operate, production efficiency is high.In addition, with respect to the processing technology of traditional die, the production of this chip need not adopt expensive litho machine, has reduced widely production threshold and production cost; And the production of this chip does not have light radiation, without the chemical reagent such as photoresist, developer solution, comparatively environmental protection, can not endanger laboratory technician's health.
The foregoing is only preferred embodiment of the present utility model; not in order to limit the utility model; all any modifications of doing within spirit of the present utility model and principle, be equal to and replace and improvement etc., within all should being included in protection domain of the present utility model.

Claims (5)

1. a novel micro-fluidic chip, it is characterized in that, comprise stacked ground floor, the second layer and the 3rd layer, the described second layer is two-sided adhering film, it is arranged between described ground floor and the 3rd layer, and described ground floor and the 3rd layer are pasted fixing; On described two-sided adhering film, be integrated with the required micro-structural of micro-fluidic chip; Described micro-structural includes the micro-reservoir, connector, window and the microchannel that are connected successively.
2. novel micro-fluidic chip as claimed in claim 1, is characterized in that, described ground floor is made up of any material in PDMS, plastics, glass or cyclic olefine copolymer material.
3. novel micro-fluidic chip as claimed in claim 1 or 2, is characterized in that, is made up for described the 3rd layer of glass or cyclic olefine copolymer material.
4. novel micro-fluidic chip as claimed in claim 1, is characterized in that, described micro-structural is etched on the second layer of described chip by laser engraving machine.
5. novel micro-fluidic chip as claimed in claim 2, is characterized in that, described ground floor is made up of pmma material.
CN201320387374.4U 2013-07-01 2013-07-01 Novel microfluidic chip Expired - Fee Related CN203663854U (en)

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CN201320387374.4U CN203663854U (en) 2013-07-01 2013-07-01 Novel microfluidic chip

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Application Number Priority Date Filing Date Title
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Publications (1)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104549583A (en) * 2014-12-26 2015-04-29 华南师范大学 Manufacturing method of microfluidic chips
CN105467111A (en) * 2014-09-05 2016-04-06 宏达国际电子股份有限公司 Micro channel module
CN106115614A (en) * 2016-07-29 2016-11-16 深圳市国赛生物技术有限公司 The manufacture method of a kind of micro-fluidic chip and micro-fluidic chip
CN106238113A (en) * 2016-08-31 2016-12-21 香港大学深圳医院 A kind of micro-fluidic chip and processing technology thereof
CN106470937A (en) * 2014-07-10 2017-03-01 纳米生物系统株式会社 Micro-fluidic chip and preparation method thereof and utilize its analytical equipment
WO2018106132A1 (en) * 2016-12-09 2018-06-14 Politechnika Wrocławska Microfluidic device for cell culture in gradient of bioactive substance
WO2020010913A1 (en) 2018-07-12 2020-01-16 上海速创诊断产品有限公司 Microfluidic detection chip and manufacturing method therefor, fixing device, and centrifugal detection device

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106470937A (en) * 2014-07-10 2017-03-01 纳米生物系统株式会社 Micro-fluidic chip and preparation method thereof and utilize its analytical equipment
US10189021B2 (en) 2014-07-10 2019-01-29 Nanobiosys Inc. Microfluidic chip, manufacturing method therefor and analysis device using same
CN105467111A (en) * 2014-09-05 2016-04-06 宏达国际电子股份有限公司 Micro channel module
CN104549583A (en) * 2014-12-26 2015-04-29 华南师范大学 Manufacturing method of microfluidic chips
CN106115614A (en) * 2016-07-29 2016-11-16 深圳市国赛生物技术有限公司 The manufacture method of a kind of micro-fluidic chip and micro-fluidic chip
CN106115614B (en) * 2016-07-29 2018-07-10 深圳市国赛生物技术有限公司 The production method and micro-fluidic chip of a kind of micro-fluidic chip
CN106238113A (en) * 2016-08-31 2016-12-21 香港大学深圳医院 A kind of micro-fluidic chip and processing technology thereof
WO2018106132A1 (en) * 2016-12-09 2018-06-14 Politechnika Wrocławska Microfluidic device for cell culture in gradient of bioactive substance
WO2020010913A1 (en) 2018-07-12 2020-01-16 上海速创诊断产品有限公司 Microfluidic detection chip and manufacturing method therefor, fixing device, and centrifugal detection device
US11123731B2 (en) 2018-07-12 2021-09-21 Shanghai Igenetec Diagnostics Co., Ltd. Microfluidic detection chip, preparation method thereof, fixing device and centrifugal detection device

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Granted publication date: 20140625

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CF01 Termination of patent right due to non-payment of annual fee