CN203576470U - Spectral domain OCT detection system based on segmented spectrum optical path coding - Google Patents
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Abstract
The utility model discloses a spectral domain OCT detection system based on segmented spectrum optical path coding. A dichroscope is arranged in a traditional reference arm, and a light source spectrum is divided into two parts which reach a transmission light path and a reflecting light path respectively. By the aid of the arrangement that plane mirrors are arranged at different positions in the transmission light path and the reflecting light path, the two parts of spectrum go through different light paths in the reference arm and intervene with returning light in two different depth sections in a sample respectively. After intervening signals of the two parts of spectrum enter a detection arm, the signals are detected by pixels in different areas of CCDs in a spectrograph, and spectrum without aliasing is acquired in parallel. Accordingly, under the condition that the OCT detection arm and a sample arm in a spectral domain are not changed, a simple light splitting structure is additionally arranged in the reference arm, based on different reference light paths of a segmented spectrum, arrangement of different zero light path positions in the sample and parallel detection of OCT signals in a double-reference-arm spectral domain are achieved, and therefore the imaging range of spectral domain OCT is expanded.
Description
Technical field
This utility model relates to optical coherent chromatographic imaging (Optical Coherence Tomography is called for short OCT) technology, relates in particular to a kind of spectral coverage OCT detection system based on segmentation spectrum path encoding.
Background technology
Optical coherent chromatographic imaging (OCT) can be implemented noncontact, not damaged, the high-resolution imaging in vivo of live body internal organizational structure and physiological function, in biomedical imaging field, has a wide range of applications.Especially in field of ophthalmology, the application prospect of OCT is huge especially, common anterior ocular segment OCT(Anterior segment OCT, AS-OCT) due to the structural images of anterior ocular segment in the optical path that can provide non-contactly under quiet moving state, and do not need by stimulating Second eye to cause the respective change that regulates the observed eye of indirect observation, become the ideal tools of measuring and analyzing anterior ocular segment tissue and structure, have its incomparable advantage compared with other technology.Conventional spectral coverage OCT system at present, conventionally application high speed linear array CCD or CMOS carry out the spectral components of parallel acquisition interference signal, without axial scan, just can obtain the depth information of sample, have quick and highly sensitive feature, its system core is the rapid spectrometer in feeler arm.The imaging depth of system determines by the each component parameter in rapid spectrometer substantially, and the imaging depth of spectral coverage OCT system is conventionally in 2 ~ 3mm left and right, therefore be also not enough to measure the degree of depth (12mm ~ 14mm) of full anterior ocular segment.
In order to realize large Depth Imaging, in common spectral coverage OCT system, the implementation method of main flow has three kinds: by eliminate mirror image double imaging depth, by repeatedly switching reference arm imaging joint and utilizing the simultaneously imagings of two cover spectrogrphs.But these methods respectively have its pros and cons, in the method for the mirror image that disappears, common are B-M-mode and galvanometer and be offset the image method that disappears.Although disappear, mirror image can be realized the degree of depth multiplication of wanting, but as B-M-mode method, during use, can exist because of the cross sensitivity problem that the image quality that causes declines that declines, in while method, be also easy to bring into environmental disturbances, and software programming aspect also have more complicated requirement.By switching reference arm, reaching imaging depth multiplication also has multiple switch means, conventionally utilizes galvanometer to switch to realize.But handoff procedure can bring time loss, to a certain extent can restriction system image taking speed, and need to do the image mosaic processing in later stage, the requirement that can not arrive realtime imaging.Utilize the imaging simultaneously of two cover spectrogrphs also can reach the imaging depth of wanting, but need extra a set of spectrogrph of building, economical really not.
Summary of the invention
This utility model, for the deficiencies in the prior art, provides a kind of spectral coverage OCT detection system based on segmentation spectrum path encoding.On the basis of original spectral coverage OCT system, change the part-structure of reference arm, realize the great deep exploration of segmentation imaging simultaneously; A light source light spectrum is divided into two parts utilization, every part spectrum separately and simultaneously imaging, so just can not produce extra time loss, reduce a large amount of image mosaic work, and can be relatively select easily flexibly the target location of two sections of detections, thereby utilize the detection that realizes the spectral coverage OCT system of the large degree of depth compared with the experimental provision of simple economy, particular content is as follows:
A kind of spectral coverage OCT detection system based on segmentation spectrum path encoding of this utility model, comprises wideband light source, optoisolator, broadband optical fiber coupler, the first Polarization Controller, the second Polarization Controller, sample arm, reference arm and feeler arm; Described sample arm comprises the first collimating lens, scanning galvanometer and the first condenser lens; Described reference arm comprises the second optical fiber collimator, dichroic mirror DM, the first plane mirror and the second plane mirror; Described feeler arm comprises the 3rd optical fiber collimator, grating, the second condenser lens, ccd detector and computer;
Described wideband light source connects a port of broadband light bonder through optoisolator, and the outlet of the two ends of broadband optical fiber coupler is connected to sample arm and reference arm through the first Polarization Controller and the second Polarization Controller respectively; Wherein the first Polarization Controller connects the first collimating lens in sample arm, then after scanning galvanometer, passes through the first condenser lens, aims at sample; And the second Polarization Controller connects the second collimating lens, the second collimating lens is aimed at dichroic mirror DM, and at a plane mirror of the each placement in two outgoing limits of dichroic mirror DM.Another port of broadband optical fiber coupler connects feeler arm, respectively through the 3rd collimating lens, grating, the second condenser lens, and last alignment detector CCD, detector C CD connects computer, to carry out date processing.
Wideband light source sends detecting light beam after broadband optical fiber coupler, and a part of light enters reference arm by the first Polarization Controller, and another part light enters sample arm by the second Polarization Controller; Enter the light of sample arm part successively by being irradiated on sample after the first optical fiber collimator, scanning galvanometer and the first condenser lens, the rear orientation light Jing Yuan road of sample is back to broadband optical fiber coupler; The light that enters reference arm part arrives dichroic mirror DM through the second optical fiber collimator, according to different wavelength length, incident illumination is divided into reflection and transmission two parts, afterwards, two light are got to respectively on the first plane mirror and the second plane mirror, Bing Anyuan road turns back to band optical fiber coupling, and then interferes with the light that sample arm is returned; From broadband optical fiber coupler interference signal out, comprised that the first reference path that the first plane mirror is corresponding interferes the signal producing with sample internal information simultaneously, and the second reference path corresponding to the second plane mirror interfered the signal producing, the sample structure information of the corresponding different depth section of two parts of signals difference with sample internal information.In feeler arm, emergent light is after fiber optic collimator mirror collimation, and after grating beam splitting and condenser lens focus on, two parts of signals is detected the pixel of diverse location on device simultaneously and surveys, then imports computer into and obtain sample depth information by fast fourier transform.
Compared with background technology, the beneficial effect the utlity model has is:
1, system structure of the present utility model is relatively simple.Only need in traditional spectral coverage OCT system, for reference arm, do slightly and change: on reference arm, add the DM device for light splitting, just can realize the OCT imaging detection of the large degree of depth.
2, system structure of the present utility model can realize the large Depth Imaging of segmentation.Enter the light of reference arm by light-splitting device, get to respectively on the plane mirror of two sides.Two sides plane mirror is in sample, and correspondence produces two zero different light path positions, thereby realizes the effect that is segmented into picture.Can improve picture quality to repeating imaging with a target location like this, can realize large Depth Imaging to the imaging simultaneously of two target locations again.
3, reference arm part of the present utility model does not have moving part, is subject to environmental disturbances less, and system is relatively stable.There is not loss extra time that can introduce as in the methods such as photoswitch or galvanometer switching, do not need to do the work such as image mosaic in later stage yet, convenient, fast.
4, this utility model has done whole light source light spectrum more especially and has utilized, and this conception of species is specially adapted to the light source of wide spectrum.Can be by this utility model device, better simply a wide spectrum is divided into two parts and is used respectively, realize the large degree of depth spectral coverage OCT system based on spectral multiplexing.This concept also can be used in other system design.
Accompanying drawing explanation
Fig. 1 is the structural principle schematic diagram of this utility model system;
Fig. 2 is the reference arm enlarged diagram of this utility model system;
Fig. 3 is schematic diagram during detector detection information in this utility model system;
Fig. 4 is the imaging effect schematic diagram of this utility model system applies when anterior ocular segment.
In figure: 1, wideband light source, 2, optoisolator, 3, broadband optical fiber coupler, 4, the first Polarization Controller, 5, the second Polarization Controller, 6, the first optical fiber collimator, 7, galvanometer, 8, the first condenser lens, 9, sample, 10, the second optical fiber collimator, 11, dichroic mirror, 12, the first plane mirror, 13, the second plane mirror, 14, the 3rd optical fiber collimator, 15, grating, 16, the second condenser lens, 17, ccd detector, 18, computer, 19, sample arm, 20, reference arm, 21, feeler arm.
The specific embodiment
Below in conjunction with accompanying drawing and exemplifying embodiment, this utility model is further described:
As shown in Figure 1 and Figure 2, a kind of spectral coverage OCT detection system based on segmentation spectrum path encoding of this utility model, comprises wideband light source 1, optoisolator 2, broadband optical fiber coupler 3, the first Polarization Controller 4, the second Polarization Controller 5, sample arm 19, reference arm 20 and feeler arm 21; Described sample arm 19 comprises the first collimating lens 6, scanning galvanometer 7 and the first condenser lens 8; Described reference arm 20 comprises the second optical fiber collimator 10, dichroic mirror DM11, the first plane mirror 12 and the second plane mirror 13; Described feeler arm 21 comprises the 3rd optical fiber collimator 14, grating 15, the second condenser lens 16, ccd detector 17 and computer 18;
Described wideband light source 1 connects a port of broadband light bonder 3 through optoisolator 2, and the outlet of the two ends of broadband optical fiber coupler 3 is connected to sample arm 19 and reference arm 20 through the first Polarization Controller 4 and the second Polarization Controller 5 respectively; Wherein the first Polarization Controller 4 connects the first collimating lens 6 in sample arm 19, then after scanning galvanometer 7, passes through the first condenser lens 8, aims at sample 9; And the second Polarization Controller 5 connects the second collimating lens 10, the second collimating lens 10 and aims at dichroic mirror DM 11, and respectively on two outgoing limits of dichroic mirror DM 11 place a plane mirror.Another port of broadband optical fiber coupler 3 connects feeler arm 21, respectively through the 3rd collimating lens 14, grating 15, the second condenser lens 16, and last alignment detector CCD 17, detector C CD 17 connects computer 18, to carry out date processing.
As shown in Figure 3, Figure 4, wideband light source 1 sends detecting light beam after broadband optical fiber coupler 3, and a part of light enters reference arm 20 by the first Polarization Controller 4, and another part light enters sample arm 19 by the second Polarization Controller 5; Enter the light of sample arm part successively by being irradiated on sample after the first optical fiber collimator 6, scanning galvanometer 7 and the first condenser lens 8, the rear orientation light Jing Yuan road of sample is back to broadband optical fiber coupler; The light that enters reference arm 20 parts arrives dichroic mirror DM 11 through the second optical fiber collimator 10, according to different wavelength length, incident illumination is divided into reflection and transmission two parts, afterwards, two light is got to respectively on the first plane mirror 12 and the second plane mirror 13, Bing Anyuan road turns back to band optical fiber coupling 3, and then interferes with the light that sample arm 19 is returned; The first reference path that has simultaneously comprised the first plane mirror 12 correspondences from broadband optical fiber coupler 3 interference signal is out interfered the signal producing with sample internal information, and the second reference path of the second plane mirror 13 correspondences is interfered the signal producing, the sample structure information of the corresponding different depth section of two parts of signals difference with sample internal information.In feeler arm 21, emergent light is after fiber optic collimator mirror 14 collimations, after grating 15 light splitting and condenser lens 16 focuses on, two parts of signals is detected the pixel of diverse location on device simultaneously and surveys, then imports computer into and obtain sample depth information by fast fourier transform.
Claims (1)
1. the spectral coverage OCT detection system based on segmentation spectrum path encoding, comprises wideband light source, optoisolator, broadband optical fiber coupler, the first Polarization Controller, the second Polarization Controller, sample arm, reference arm and feeler arm; Described sample arm comprises the first collimating lens, scanning galvanometer and the first condenser lens; Described reference arm comprises the second optical fiber collimator, dichroic mirror DM, the first plane mirror and the second plane mirror; Described feeler arm comprises the 3rd optical fiber collimator, grating, the second condenser lens, ccd detector and computer;
It is characterized in that: described wideband light source connects a port of broadband light bonder through optoisolator, and the outlet of the two ends of broadband optical fiber coupler is connected to sample arm and reference arm through the first Polarization Controller and the second Polarization Controller respectively; Wherein the first Polarization Controller connects the first collimating lens in sample arm, then after scanning galvanometer, passes through the first condenser lens, aims at sample; And the second Polarization Controller connects the second collimating lens, the second collimating lens is aimed at dichroic mirror DM, and at a plane mirror of the each placement in two outgoing limits of dichroic mirror DM; Another port of broadband optical fiber coupler connects feeler arm, respectively through the 3rd collimating lens, grating, the second condenser lens, and last alignment detector CCD, detector C CD connects computer, to carry out date processing;
Wideband light source sends detecting light beam after broadband optical fiber coupler, and a part of light enters reference arm by the first Polarization Controller, and another part light enters sample arm by the second Polarization Controller; Enter the light of sample arm part successively by being irradiated on sample after the first optical fiber collimator, scanning galvanometer and the first condenser lens, the rear orientation light Jing Yuan road of sample is back to broadband optical fiber coupler; The light that enters reference arm part arrives dichroic mirror DM through the second optical fiber collimator, according to different wavelength length, incident illumination is divided into reflection and transmission two parts, afterwards, two light are got to respectively on the first plane mirror and the second plane mirror, Bing Anyuan road turns back to band optical fiber coupling, and then interferes with the light that sample arm is returned; From broadband optical fiber coupler interference signal out, comprised that the first reference path that the first plane mirror is corresponding interferes the signal producing with sample internal information simultaneously, and the second reference path corresponding to the second plane mirror interfered the signal producing, the sample structure information of the corresponding different depth section of two parts of signals difference with sample internal information; In feeler arm, emergent light is after fiber optic collimator mirror collimation, and after grating beam splitting and condenser lens focus on, two parts of signals is detected the pixel of diverse location on device simultaneously and surveys, then imports computer into and obtain sample depth information by fast fourier transform.
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103565405A (en) * | 2013-11-15 | 2014-02-12 | 浙江大学 | Spectral domain OCT detecting system and method based on segmented spectrum optical path coding |
| CN108272432A (en) * | 2017-07-20 | 2018-07-13 | 中山大学中山眼科中心 | A kind of ophthalmology high speed, high resolution multifunctional optical coherence tomography device based on slit-lamp platform |
| CN109008942A (en) * | 2018-09-15 | 2018-12-18 | 中山大学中山眼科中心 | A kind of full optics of the eye coherence tomography device and imaging method based on slit-lamp platform |
| CN109341518A (en) * | 2018-08-22 | 2019-02-15 | 深圳市斯尔顿科技有限公司 | OCT detection device and microscopic carvings equipment |
| CN110336928A (en) * | 2019-03-15 | 2019-10-15 | 浙江工业大学 | A kind of OCT spectroscopic acquisition and Transmission system based on ZYNQ |
| CN110448267A (en) * | 2019-09-06 | 2019-11-15 | 重庆贝奥新视野医疗设备有限公司 | A kind of multimode eyeground dynamic imaging analysis system and its method |
| CN113447482A (en) * | 2021-06-22 | 2021-09-28 | 无锡欧因特光学科技有限公司 | Industrial OCT detection equipment capable of quickly positioning and focusing |
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2013
- 2013-11-15 CN CN201320725919.8U patent/CN203576470U/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103565405A (en) * | 2013-11-15 | 2014-02-12 | 浙江大学 | Spectral domain OCT detecting system and method based on segmented spectrum optical path coding |
| CN103565405B (en) * | 2013-11-15 | 2015-12-09 | 浙江大学 | Based on the spectral coverage OCT detection method of segmentation spectrum path encoding |
| CN108272432A (en) * | 2017-07-20 | 2018-07-13 | 中山大学中山眼科中心 | A kind of ophthalmology high speed, high resolution multifunctional optical coherence tomography device based on slit-lamp platform |
| CN109341518A (en) * | 2018-08-22 | 2019-02-15 | 深圳市斯尔顿科技有限公司 | OCT detection device and microscopic carvings equipment |
| CN109008942A (en) * | 2018-09-15 | 2018-12-18 | 中山大学中山眼科中心 | A kind of full optics of the eye coherence tomography device and imaging method based on slit-lamp platform |
| CN110336928A (en) * | 2019-03-15 | 2019-10-15 | 浙江工业大学 | A kind of OCT spectroscopic acquisition and Transmission system based on ZYNQ |
| CN110448267A (en) * | 2019-09-06 | 2019-11-15 | 重庆贝奥新视野医疗设备有限公司 | A kind of multimode eyeground dynamic imaging analysis system and its method |
| CN110448267B (en) * | 2019-09-06 | 2021-05-25 | 重庆贝奥新视野医疗设备有限公司 | Multimode fundus dynamic imaging analysis system and method |
| CN113447482A (en) * | 2021-06-22 | 2021-09-28 | 无锡欧因特光学科技有限公司 | Industrial OCT detection equipment capable of quickly positioning and focusing |
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