CN203432983U - Biological micro-sample measuring system - Google Patents
Biological micro-sample measuring system Download PDFInfo
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- CN203432983U CN203432983U CN201320587459.7U CN201320587459U CN203432983U CN 203432983 U CN203432983 U CN 203432983U CN 201320587459 U CN201320587459 U CN 201320587459U CN 203432983 U CN203432983 U CN 203432983U
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Abstract
The utility model relates to the production technical field of a precision measuring instrument, in particular to a biological micro-sample measuring system, which comprises a mechanics loading module, an electric measuring module, a microimaging module and a computer control module, wherein the mechanics loading module, the electric measuring module and the microimaging module are respectively and electrically connected with the computer control module. The mechanics loading module, the electric measuring module and the microimaging module are respectively and electrically connected with the computer control module, so that the mechanics loading module, the electric measuring module and the microimaging module can be controlled to be quickly and precisely operated and to be automatically corrected, the time can be saved; moreover, the biological micro-sample measuring system is large in measurement range, high in measurement precision, simple to operate, convenient to use, capable of integrating the measurement and microimaging and high in economic benefits and social benefits.
Description
Technical field
The utility model relates to a kind of manufacture technology field of fine measuring instrument, more specifically, relates to the micro-sample measurement system of a kind of biology.
Background technology
The research of the problems such as the differentiation of biomechanics irritation cell, induced growth, bioelectricity conduction is the study hotspot of current scientific research circle, and how in vitro for, the suffered micro-power of analog cell skeleton stimulates and is a great problem that scientific research circle faces at present by the bioelectrical signals measurement in real time of suffered mechanical stimulation generation.Micro-power operation and the bioelectric measurement instrument of biomedical scientific research field can solve this difficult problem.Domestic colleges and universities and Research Center are also carrying out a lot of theories and applied research as units such as the Chinese Academy of Sciences, Chinese University of Science and Technology, University Of Chongqing, Zhejiang University aspect the measurement of microcosmic power, but substantially all in theoretical conceptual phase, the design of instrument and manufacture very shortcoming.
Also there are at present the research of micro-sample measurement, for example atomic force microscope, nano-hardness tester and micro-force test system abroad.Although atomic force microscope can carry out the measurement of micro-sample, be mainly can only reach 1mN to the detection of micro-sample microscopic appearance and its maximum working load.Nano-hardness tester also can carry out the measurement of micro-sample, but is mainly can only reach 12.6mN to the detection of material surface mechanical property and maximum working load.Micro-force test system can carry out micron order measurement to sample, but does not possess the comprehensive functions such as the needed micro-imaging of micron order specimen test, microoperation, bioelectric measurement.
Utility model content
The utility model is at least one defect overcoming described in above-mentioned prior art, provide a kind of biology micro-sample measurement system, biological micro-sample measurement system measurement range is large, measuring accuracy is high, simple to operate, easy to use, and collection measurement and micro-imaging and one, very high economic benefit and social benefit there is.
For solving the problems of the technologies described above, the technical solution adopted in the utility model is:
Provide a kind of biology micro-sample measurement system, comprise Mechanical loading module, electrical measurement module, micro-imaging module, computer control module, described Mechanical loading module, electrical measurement module, micro-imaging module are electrically connected to computer control module respectively.
On the biological micro-sample measurement system of the utility model, be provided with Mechanical loading module, electrical measurement module, micro-imaging module, computer control module, be specially Mechanical loading module, electrical measurement module, micro-imaging module and be electrically connected to computer control module respectively.It is complete measurement imaging operation and automatically revise in order to control described Mechanical loading module, electrical measurement module, micro-imaging module with computing machine that Mechanical loading module, electrical measurement module, micro-imaging module are electrically connected to computer control module respectively, make described Mechanical loading module, electrical measurement module, micro-imaging module accurate complete operation fast, and save time.
One of improve, described Mechanical loading module comprises fixture module, locating module, micro-power load-on module, and described fixture module, locating module, micro-power load-on module are electrically connected to computer control module respectively.The setting of fixture module is in order to be used for, sample to be clamped, so that the carrying out of follow-up measurement.The setting of locating module is for sample being carried out to accurate location fast, is convenient to the carrying out of micro-power load-on module.The setting of micro-power load-on module is for the micro-sample of biology is carried out to Mechanical loading, makes biological micro-sample be subject to the spread effect of power.The setting of computer control module is in order to make fixture module, locating module, integrated the completing of micro-power load-on module, makes this three large module mutually restrict, more accurately complete operation simultaneously.
Preferably, described fixture module is provided with collar fixture position, magnet fixture position, pellicle fixture position, double dish fixture position, and collar fixture position, magnet fixture position, pellicle fixture position, double dish fixture position lay respectively at four orientation of fixture module.It is in order to complete the clamping to different biological samples that fixture module arranges four fixture positions.Wherein collar fixture position and magnet fixture position are for the clamping to one dimension samples such as fiber, blood capillaries, pellicle fixture position is for the clamping to two-dimentional samples such as gelatin film, hydrogel thin films, and double dish fixture position is for the clamping to three-dimensional samples such as bulks.Four orientation that collar fixture position, magnet fixture position, pellicle fixture position, double dish fixture lay respectively at fixture module are the positions of placing for the ease of distinguishing different biological samples.
Preferably, described magnet fixture position, pellicle fixture position, double dish fixture position lay respectively at wherein three orientation of fixture module upper surface, and collar fixture position is positioned at the sidewall of the position, four directions of fixture module.The sidewall that collar fixture position is arranged on the position, four directions of fixture module is for the ease of the clamping to annular sample.
Preferably, described locating module comprises linear electric motors and two driving elements of piezoelectric ceramics promoters, and described linear electric motors and piezoelectric ceramics device are electrically connected to computer control module, and described linear electric motors complete coarse positioning, and described piezoelectric ceramics device completes fine positioning.The setting of linear electric motors and piezoelectric ceramics promoters is in order to complete the location of microbiological specimens, is convenient to the carrying out of follow-up work.Utilize computer control module to control linear electric motors and piezoelectric ceramics promoters completes the location to the micro-sample of biology, piezoelectric ceramics promoters built-in sensitive device is used for feeding back locating information, and then controls by computer control module the correction that locating module carries out Sample location.
Preferably, described micro-power load-on module comprises linear electric motors, piezoelectric ceramics promoters, Micro-force sensor, data collecting card, control module.Described linear electric motors, piezoelectric ceramics promoters, Micro-force sensor are electrically connected to control module, control module is electrically connected to computer control module, described piezoelectric ceramics promoters inside is provided with induction installation, described Micro-force sensor is used for loading force measurement, the Mechanical loading of described control module control device.The setting of micro-power load-on module is in order to complete the process of the stressed stimulation of biological micro-sample.Utilize linear electric motors and piezoelectric ceramics promoters to complete the running fix process to the micro-sample of biology, piezoelectric ceramics promoters can drive Micro-force sensor motion, Micro-force sensor can be responded to loaded mechanical signal and then feed back to control module, the last mechanical information loading that shows on computers.Data collecting card and control module according to the data of setting (as constant stress loading etc.) control piezoelectric ceramics promoters and move downward the effect that the micro-sample of biology is applied to power, the Micro-force sensor of piezoelectric ceramics internal displacement sensor and piezoelectric ceramics promoters lower end can feed back displacement and mechanical information to data collecting card and control module simultaneously.
Two of improvement, described electrical measurement module comprises that described biological microneedle electrodes, data acquisition card are electrically connected to computer control module for biological sample cell being carried out to electrometric biological microneedle electrodes and being used for that the signal of measuring is gathered to the data acquisition card of storing.The setting of electrical measurement module is to be subject in order to complete the cell of biological sample the measurement that loading force stimulates the electric signal producing, and realizes the measurement to bioelectrical signals on cellular level.When Mechanical loading module is implemented Mechanical loading to the micro-sample of biology, the biological microneedle electrodes of electrical measurement module is inserted near the of biological sample cell or inserts in cell body, the bioelectrical signals producing can feed back by microelectrode, the bioelectrical signals that gathers cell mass or individual cells with data acquisition card, is then transferred on computing machine and shows.Data acquisition card and computer control module are controlled biological microneedle electrodes, make biological microneedle electrodes insert biological micro-sample destination locations, when the micro-sample of biology is subject to micro-power loading, the bioelectrical signals of generation can feed back to data collecting card and computer control unit by biological microneedle electrodes.
Three of improvement, described micro-imaging module comprises for the micro-sample of biology being carried out to multiplying arrangement, for gathering camera, image pick-up card, the servomotor of the micro-sample of biology after multiplying arrangement amplifies, driven by servomotor camera is realized focusing, and described multiplying arrangement, camera, image pick-up card, servomotor are electrically connected to computer control module.The setting of micro-imaging module is in order to collect the picture signal of biological sample cell and the picture signal of Micro-force sensor probe, then pass through Computer display, contrast Micro-force sensor probe and biological sample cell position relationship in height, then carry out parameter setting, control the movement of servomotor, to Micro-force sensor probe is accurately located to Measurement accuracy loading force.
Compared with prior art, the beneficial effects of the utility model are:
On the biological micro-sample measurement system of the utility model, be provided with Mechanical loading module, electrical measurement module, micro-imaging module, computer control module, Mechanical loading module, electrical measurement module, micro-imaging module are electrically connected to computer control module respectively.Being electrically connected to setting is in order to control described Mechanical loading module, electrical measurement module, micro-imaging module complete operation with computing machine and automatically to revise, make described Mechanical loading module, electrical measurement module, micro-imaging module accurate complete operation fast, save time, and biological micro-sample measurement system measurement range is large, measuring accuracy is high, simple to operate, easy to use, collection measurement and micro-imaging and one, have very high economic benefit and social benefit.
Accompanying drawing explanation
Fig. 1 is the structural representation of biological micro-sample measurement system.
Fig. 2 is the use process flow diagram of biological micro-sample measurement system.
Fig. 3 is fixture module diagram.
Fig. 4 is sample positioning stage schematic diagram.
Fig. 5 is micro-power load-on module schematic diagram.
Fig. 6 is micro-power load-on module function realizing circuit block diagram.
Fig. 7 is that electrical measurement functions of modules realizes circuit block diagram.
Fig. 8 is micro-imaging module diagram.
Fig. 9 is that micro-imaging functions of modules realizes circuit block diagram.
Embodiment
Below in conjunction with embodiment, the utility model is further described.Wherein, accompanying drawing is only for exemplary illustration, expression be only schematic diagram, but not pictorial diagram can not be interpreted as the restriction to this patent; For embodiment of the present utility model is described better, some parts of accompanying drawing have omission, zoom in or out, and do not represent the size of actual product; For a person skilled in the art, in accompanying drawing some known features and explanation thereof may to omit be understandable.
The corresponding same or analogous parts of same or analogous label in the accompanying drawing of the utility model embodiment, in description of the present utility model, it will be appreciated that, if have term " on ", D score, " left side ", orientation or the position relationship of indications such as " right sides " are based on orientation shown in the drawings or position relationship, only the utility model and simplified characterization for convenience of description, rather than device or the element of indication or hint indication must have specific orientation, with specific orientation structure and operation, therefore the term of describing position relationship in accompanying drawing is only for exemplary illustration, can not be interpreted as the restriction to this patent, for the ordinary skill in the art, can understand as the case may be the concrete meaning of above-mentioned term.
Embodiment 1
Be biological micro-sample measurement system the first embodiment of the utility model as shown in Figures 1 to 9.As shown in Figure 1 to Figure 2, biological micro-sample measurement system comprises Mechanical loading module 1, electrical measurement module 2, micro-imaging module 3, computer control module 4, and Mechanical loading module 1, electrical measurement module 2, micro-imaging module 3 are electrically connected to computer control module 4 respectively.Concrete, Mechanical loading module 1 comprises fixture module 11, locating module 12, micro-power load-on module 13, fixture module 11, locating module 12, micro-power load-on module 13 are electrically connected to computer control module 4 respectively.It is complete measurement imaging operation and automatically revise in order to control described Mechanical loading module 1, electrical measurement module 2, micro-imaging module 3 with computing machine that Mechanical loading module 1, electrical measurement module 2, micro-imaging module 3 are electrically connected to computer control module 4 respectively, make described Mechanical loading module 1, electrical measurement module 2, micro-imaging module 3 accurate complete operation fast, and save time.The setting of fixture module 11 is in order to be used for, sample to be clamped, so that the carrying out of follow-up measurement.The setting of locating module 12 is for sample being carried out to accurate location fast, is convenient to the carrying out of micro-power load-on module 13.The setting of micro-power load-on module 13 is for the micro-sample of biology is carried out to Mechanical loading, makes biological micro-sample be subject to the spread effect of power.The micro-sample of biology of selecting in the present embodiment is the mesenchymal stem cells MSCs group after fluorescent dye transfect cell core.
Wherein, as shown in Figure 3, fixture module 11 is provided with collar fixture position 111, magnet fixture position 112, pellicle fixture position 113, double dish fixture position 114, and fixture position is not both for the clamping to different samples, selects double dish fixture position 114 in the present embodiment.Magnet fixture position 112, pellicle fixture position 112,114 of double dish fixtures lay respectively at wherein three orientation of fixture module 11 upper surfaces, and collar fixture position 111 is positioned at the sidewall of the position, four directions of fixture module.In the present embodiment, biological sample is positioned at the upper surface of fixture module 11.
As shown in Figure 5, locating module 12 comprises linear electric motors 121 and 122 two driving elements of piezoelectric ceramics promoters, linear electric motors 121 and piezoelectric ceramics device 122 are electrically connected to computer control module 4, and linear electric motors 121 complete coarse positioning, and piezoelectric ceramics promoters 122 completes fine positioning.The setting of linear electric motors 121 and piezoelectric ceramics promoters 122 is in order to complete the location of microbiological specimens, is convenient to the carrying out of follow-up work.The location that utilizes computer control module 4 control linear electric motors 121 and piezoelectric ceramics promoters 122 to complete biological micro-sample, piezoelectric ceramics promoters 122 built-in sensitive devices are used for feeding back locating information, and then by computer control module 4, control locating module 12 and carry out the correction of Sample location.As shown in Figure 4, what under locating module 12, arrange is sample positioning stage, on sample positioning stage, be provided with the manual slide unit A of XYZ, XY micron positioning table B, XY nanometer positioning platform C, utilize the manual slide unit A of XYZ by sample coarse adjustment under piezoelectric ceramics promoters 122 and Micro-force sensor 133, by computer control XY micron positioning table B and XY nanometer positioning platform C, sample fine tuning is arrived to destination locations, on worktable, be provided with inverted fluorescence microscope, can utilize it to observe the position of micro-sample levels direction, by computer control module 4, control XY micron positioning table B and XY nanometer positioning platform C completes the axial location of XY, the location that the motion that utilizes computer control module 4 to control linear electric motors 121 completes Z axis.In embodiment, the parameter of locating module 12 is 50 μ m for locating step pitch fast, and locating speed is 100 μ m/s fast, and accurately locating step pitch is 200 nm, and accurately locating speed is 200nm/s, and displacement and force signal acquisition channel sample frequency are 2 KHz.
As shown in Figure 5, micro-power load-on module 13 comprises linear electric motors 121, piezoelectric ceramics promoters 122, Micro-force sensor 133, data collecting card, control module.Linear electric motors 121, piezoelectric ceramics promoters 122, Micro-force sensor 133, capture card are electrically connected to control module, piezoelectric ceramics promoters 122 inside are provided with the variation that induction installation displacement transducer can inductive displacement, Micro-force sensor 133 is used for loading force measurement, data collecting card is for the collection to displacement variable signal and loading force signal, and control module is for the Mechanical loading of control device.The setting of micro-power load-on module 13 is in order to complete the process of the stressed stimulation of biological micro-sample and measurement.Utilize linear electric motors 121 and piezoelectric ceramics promoters 122 to complete the running fix process to the micro-sample of biology, piezoelectric ceramics promoters 122 can drive Micro-force sensor 133 motions, Micro-force sensor 133 can be responded to loaded mechanical signal and then through data collecting card collection, feed back to control module and can carry out the control of sample loading force, realize the various Mechanical loading patterns such as constant speed, constant stress, constant strain, permanent acceleration, fatigue, finally show on computers mechanical information and the displacement information loading, react the mechanical characteristics of biological micro-sample.As shown in Figure 6, data collecting card and control module according to the data of setting (as constant stress loading etc.) control piezoelectric ceramics promoters 122 and move downward the effect that the micro-sample of biology is applied to power, simultaneously the Micro-force sensor 133 of piezoelectric ceramics internal displacement sensor and piezoelectric ceramics promoters lower end can feedback displacements and mechanical information to data collecting card and control module.
In addition, as shown in Figure 7, electrical measurement module 2 comprises biological microneedle electrodes 21 and data acquisition card, and biological microneedle electrodes 21 is used for biological sample cell to carry out electrical measurement, and data acquisition card is used for the signal of measuring to gather.The setting of electrical measurement module 2 is to stimulate the electric signal producing to measure for the cell of biological sample being subject to loading force, realizes the measurement to bioelectrical signals on cellular level.When the micro-sample of 1 pair of biology of Mechanical loading module is implemented Mechanical loading, the biological microneedle electrodes 21 of electrical measurement module 2 is inserted near the of biological sample cell or inserts in cell body, the bioelectrical signals that gathers cell mass or individual cells with data acquisition card, is then transferred on computing machine and shows.Data acquisition card and computer control module 4 are controlled biological microneedle electrodes 21, make biological microneedle electrodes 21 insert biological micro-sample destination locations, when the micro-sample of biology is subject to micro-power loading, the bioelectrical signals of generation can feed back to data collecting card and computer control module 4 by biological microneedle electrodes 21.
As shown in Fig. 8 to Fig. 9, micro-imaging module 3 is by multiplying arrangement 31, camera 32, image pick-up card, servomotor.Multiplying arrangement 31 is used for the micro-sample of biology to amplify, and camera 32 is used for biological sample to carry out image acquisition, and image pick-up card is used for the picture signal gathering to process, and servomotor is used for micro-imaging module to carry out running fix.The setting of micro-imaging module 3 is in order to collect the picture signal of biological sample cell and the picture signal of Micro-force sensor 133 probes, then by Computer display, go out probe and the biological sample cell position relationship in height of Micro-force sensor 133, finally carry out parameter setting, control the movement of servomotor, to Micro-force sensor 133 probes are accurately located to Measurement accuracy loading force.In Fig. 9, executive system is servomotor, and optical system is multiplying arrangement 31, and CCD is the photoreceptor of camera 32.
Specific implementation method of the present utility model is as follows: first the mesenchymal stem cells MSCs group after fluorescent dye transfect cell core put into 114 li of the double dish fixture positions of fixture module 11 and place level.
Secondly on computer control panel, positional parameter is set, setting location step pitch is fast 50 μ m, locating speed is 100 μ m/s fast, accurately location step pitch is 200 nm, and accurately locating speed is 200nm/s, and displacement and force signal acquisition channel sample frequency are 2 KHz, also need to arrange the test environment parameter of biological sample, Temperature Setting is 37 ℃, and gas concentration lwevel is set as 5%, and humidity is 95%.Then regulate the cell mass sample in the fixture module 11 that the operating rod of external device inverted fluorescence microscope makes to be connected with microscope stage to be positioned at field of microscope central authorities, operations button by microscope fuselage regulates the parameters such as object lens distance, transillumination, makes Computer display cell sample image clearly.
Then according to the image information of fluorescent microscope feedback, position, at computer control panel axis, select to select X, Y-axis in option, according to the image information of inverted fluorescence microscope feedback, " F.F. " or " slow-motion " of clicking interface regulates locating module 12, and Micro-force sensor 133 probes are overlapped with the micro-sample of cell mass at X-axis, Y-axis both direction; At axle, select to select Z axis in option, " F.F. " or " slow-motion " of clicking interface regulates locating module 12, Micro-force sensor 133 approached in Z-direction and the micro-sample of cell mass as far as possible, but do not contact.
Also some parameters in micro-power load-on module 13 need be set in control panel, setting Mechanical loading speed is 200nm/s, and loading distance is 50 μ m, clicks " starting to load ", and the Mechanical loading limit is 1N.Piezoelectric ceramics promoters 122 drives Micro-force sensors 133 to approach to cell mass sample according to setting loading parameters, in 133 exposing cell sample moments of Micro-force sensor, produces mechanical signal sudden change, now represents that test formally starts.Load always and continue, until reach setpoint distance or surpass the Mechanical loading limit or artificial " loading stops " key of clicking, finish the Mechanical loading to cell sample.The displacement sensor displacement signal that piezoelectric ceramics promoters 122 is built-in, Micro-force sensor 133 is measured mechanical signal.Then by data collecting card, carry out displacement and be subject to the data acquisition of force signal and be transferred on computing machine to show.
Meanwhile, according to the data parameters on computer control panel, regulate the biological microneedle electrodes 21 of electrical measurement module 2, make biological microneedle electrodes 21 accurately insert near cell mass sample or directly insert in cell.Biological microneedle electrodes 21 accurately inserted near cell mass sample when 13 pairs of cell samples of micro-power load-on module apply micro-power loading or directly insert in cell, utilize data acquisition card to carry out data acquisition save data to measured electric signal, be then transferred on computing machine and show.
Finally, in micro-imaging module 3, the high magnified glass of multiplying arrangement 31 carries out optical amplifier to Micro-force sensor 133 probes with cell sample, camera 32 is converted into data image signal by the optical signalling after amplifying, image pick-up card carries out pre-service to picture signal, computing machine utilizes Image Definition to be for further processing to picture signal and drives servomotor to adjust camera lens according to result and makes it be positioned at optimal imaging position, and computing machine has Micro-force sensor 133 probes of high definition and cell sample at the position relationship of short transverse by demonstration.
Obviously, above-described embodiment of the present utility model is only for the utility model example is clearly described, and is not the restriction to embodiment of the present utility model.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here exhaustive without also giving all embodiments.All any modifications of doing within spirit of the present utility model and principle, be equal to and replace and improvement etc., within all should being included in the protection domain of the utility model claim.
Claims (8)
1. the micro-sample measurement system of biology, it is characterized in that, comprise Mechanical loading module, electrical measurement module, micro-imaging module, computer control module, described Mechanical loading module, electrical measurement module, micro-imaging module are electrically connected to computer control module respectively.
2. the micro-sample measurement system of biology according to claim 1, it is characterized in that, described Mechanical loading module comprises fixture module, locating module, micro-power load-on module, and described fixture module, locating module, micro-power load-on module are electrically connected to computer control module respectively.
3. the micro-sample measurement system of biology according to claim 2, it is characterized in that, described fixture module is provided with collar fixture position, magnet fixture position, pellicle fixture position, double dish fixture position, and collar fixture position, magnet fixture position, pellicle fixture position, double dish fixture position lay respectively at four orientation of fixture module.
4. the micro-sample measurement system of biology according to claim 3, it is characterized in that, described magnet fixture position, pellicle fixture position, double dish fixture position lay respectively at wherein three orientation of fixture module upper surface, and collar fixture position is positioned at the sidewall of the position, four directions of fixture module.
5. the micro-sample measurement system of biology according to claim 2, is characterized in that, described locating module comprises linear electric motors and two driving elements of piezoelectric ceramics promoters, and described linear electric motors and piezoelectric ceramics promoters are electrically connected to computer control module.
6. the micro-sample measurement system of biology according to claim 2, is characterized in that, described micro-power load-on module comprises linear electric motors, piezoelectric ceramics promoters, Micro-force sensor, data collecting card, control module; Described linear electric motors, piezoelectric ceramics promoters, Micro-force sensor are electrically connected to control module, described piezoelectric ceramics promoters inside is provided with induction installation, described Micro-force sensor is used for loading force measurement, the Mechanical loading of described control module control survey system.
7. the micro-sample measurement system of biology according to claim 1, it is characterized in that, described electrical measurement module comprises that described biological microneedle electrodes, data acquisition card are electrically connected to computer control module for biological sample cell being carried out to electrometric biological microneedle electrodes and being used for that the signal of measuring is gathered to the data acquisition card of storing.
8. the micro-sample measurement system of biology according to claim 1, it is characterized in that, described micro-imaging module comprises multiplying arrangement for the micro-sample of biology is amplified, for gathering camera, image pick-up card, the servomotor of the micro-sample of biology after multiplying arrangement amplifies, driven by servomotor camera is realized focusing, and described multiplying arrangement, camera, image pick-up card, servomotor are electrically connected to computer control module.
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| CN201320587459.7U CN203432983U (en) | 2013-09-23 | 2013-09-23 | Biological micro-sample measuring system |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103513046A (en) * | 2013-09-23 | 2014-01-15 | 中山大学 | Micro biological sample measurement system |
| CN111912993A (en) * | 2019-05-07 | 2020-11-10 | 旭月(北京)科技有限公司 | High-throughput automatic rapid non-damage micrometering system and method |
-
2013
- 2013-09-23 CN CN201320587459.7U patent/CN203432983U/en not_active Withdrawn - After Issue
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103513046A (en) * | 2013-09-23 | 2014-01-15 | 中山大学 | Micro biological sample measurement system |
| CN103513046B (en) * | 2013-09-23 | 2015-07-22 | 中山大学 | Micro biological sample measurement system |
| CN111912993A (en) * | 2019-05-07 | 2020-11-10 | 旭月(北京)科技有限公司 | High-throughput automatic rapid non-damage micrometering system and method |
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