CN203425059U - Rat heart perfusion fixation device - Google Patents
Rat heart perfusion fixation device Download PDFInfo
- Publication number
- CN203425059U CN203425059U CN201320423889.5U CN201320423889U CN203425059U CN 203425059 U CN203425059 U CN 203425059U CN 201320423889 U CN201320423889 U CN 201320423889U CN 203425059 U CN203425059 U CN 203425059U
- Authority
- CN
- China
- Prior art keywords
- clamp
- catheter needle
- rat heart
- perfusion
- heart
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The utility model provides a rat heart perfusion fixation device which comprises a clamp and a perfusion needle fixer. The clamp comprises two clamp holders, a hinging shaft and a spring, the two clamp holders are connected through the hinging shaft, each clamp holder is divided into a clamp leaf portion and a clamp arm portion with the hinging shaft as a boundary, and the spring is connected between the clamp arm portions of the two clamp holders. The perfusion needle fixer is a pipe with openings at two ends, a hole penetrating the hinging shaft is formed in the hinging shaft, the hole enables the area between the clamp leaf positions and the area between the clamp arm portions to be communicated, and the perfusion needle fixer is communicated with the hole. The rat heart perfusion fixation device is simple to manufacture and convenient to operate and can effectively reduce the situations that insertion of a perfusion needle fails in operation, perfusion is not complete due to the fact that the heart is pierced, and the perfusion needle is poor in fixation. The perfusion needle effectively penetrates through a heart wall layer to enable the tail end of a perfusion needle head to be located in the middle of a ventricular chamber, and adverse events of puncture failure, piercing and the like are prevented from occurring.
Description
Technical field
This utility model relates to a kind of technical field of medical instruments, relates in particular to a kind of convenience, safety, the fixture of rat heart perfusion efficiently.
Background technology
At present, cardiovascular disease has become commonly encountered diseases, the frequently-occurring disease of harm humans health, and wherein, no matter be former or secondary, the final ischemia/anoxia of cardiovascular organization that different inducement was caused of all take is its main pathogenesis.Therefore the research of cardiovascular ischemia/anoxia seem extremely urgent.
Perfusion fixation is applied the getting express developed of very extensive ，Ta Dui nervous tissue (brain, spinal cord) in the research of heart ischemia/Anoxic Phase related disorders, fixation is that any in vitro fixation is all irreplaceable.Through the fixing animal tissue cell of heart perfusion, it is one of key problem in technology of experimental morphology research.Patent CN201394094Y provides a kind of minitype animal experiment to pour into fixing apparatus, comprises support, liquid holding device, liquid conducting pipes, tee T, liquid selective/switching device shifter, flow velocity regulation device and sting device.Yet, this utility model for be carefully to pour into the experimentation that fixation is won cerebral tissue, and complex structure, complex operation.
The heart perfusion fixedly normal experiment method of rat tissue's cell is as follows: after rat anesthesia, lie on the back fixing, open abdomen, open breast (hemostasis clamp xiphoid-process, shears is cut off along the breastbone left and right sides, before thorax, turns over) fully expose thoracic cavity, see the heart of beating, the apex of the heart inserts perfusion syringe needle, enter left ventricle or inject aorta, mosquito forceps is fixed, and cuts off subsequently postcava, superior vena cava or cuts off right auricle, open venous blood, pours into.Because heart surface is smooth and always in the state of beating, when the apex of the heart inserts catheter needle, need fixedly after heart, insert catheter needle (firmly wanting suitably in case insertion right ventricle, left atrium or slotting punching are dirty during attention operation) with hands, after catheter needle inserts, open filling system, after whether observation is unobstructed, utilize vascular forceps clamp heart to fix.
Yet there is many deficiencies in these conventional fixing meanss in actual experiment operation, as: with hands, fixedly during heart, due to the smooth easy slippage sometimes of heart surface, affect the insertion of catheter needle; The firmly degree that catheter needle inserts is difficult to grasp; Vascular forceps is fixedly time, because heart surface is smooth, heartbeat brings certain difficulty (as clamp misplaces, presss from both sides catheter needle head end, excessive clamp causes rupture of heart or catheter needle distortion etc. and all can cause perfusion failure by mistake) to clamp, sometimes also need other people to cooperate.
Utility model content
For existing heart perfusion fixture limitation in the use, for example, with the fixing heart of hands, the firmly degree that catheter needle is inserted in the insertion that easy slippage affects catheter needle is simultaneously difficult to grasp, and by vascular forceps fixedly time, easily generation clamp misplaces, presss from both sides by mistake catheter needle head end, excessively clamp causes the problems such as rupture of heart or catheter needle distortion, this utility model provides a kind of convenience, safety, the fixture of rat heart perfusion efficiently, and it comprises following technical scheme:
A kind of rat heart perfusion fixture, it is characterized in that, comprise clip, catheter needle holder, wherein, clip comprises two clamp holders, jointed shaft and springs, in the middle of two clamp holders, by jointed shaft, connects, and take jointed shaft as boundary, clamp holder is divided into folder leaf part and jig arm part, in two clamp holders, between jig arm, is connected with spring;
The pipe that described catheter needle holder is both ends open, is equipped with the hole of running through described jointed shaft in described jointed shaft, region between region and jig arm part between described hole connection folder leaf part, and catheter needle holder is communicated with described hole.
The rat heart perfusion fixture that this utility model is above-mentioned, wherein, catheter needle holder and described hole mode of communicating are unrestricted, are preferably and insert in described hole or connect described hole, more preferably insert in described hole at least partly, most preferably are from hole and pass.
The above-mentioned rat heart of this utility model perfusion fixture, wherein, catheter needle fixedly on wall with at least one opening, at least one end of opening is provided with draw-in groove, the one end that is preferably close jointed shaft is provided with draw-in groove.
The rat heart perfusion fixture that this utility model is above-mentioned, wherein, also comprise catheter needle, described catheter needle can insert catheter needle holder, and can extend in two clamp holders and press from both sides leaf part, being preferably, catheter needle comprises syringe needle, backshank and fastener, fastener is arranged on backshank one side, and described fastener can slide along the opening on catheter needle holder and be stuck in described draw-in groove.
The above-mentioned rat heart of this utility model perfusion fixture, wherein, presss from both sides leaf side in opposite directions and is provided with rubbing surface in two clamp holders, make to press from both sides leaf and clamp heart and be difficult for slippage, and also cardioprotection tissue is without prejudice simultaneously.
The rat heart perfusion fixture that this utility model is above-mentioned, wherein, also comprise adjustable column and adjusting nut, adjustable column is arranged in a described jig arm and is enclosed within described spring, adjustable column bottom arranges adjusting nut, described adjustable column and adjusting nut capable of regulating spring pressure, make clip can clamp more closely heart.
The rat heart perfusion fixture that this utility model is above-mentioned, wherein, described catheter needle backshank is connected with tee T, by tee T, is connected with tube for transfusion.
The rat heart perfusion fixture that this utility model is above-mentioned, wherein, catheter needle holder length is preferably 10-40mm, and more preferably 20-30mm, most preferably is 25mm.
The rat heart perfusion fixture that this utility model is above-mentioned, wherein, the distance of described draw-in groove and jointed shaft mesopore is preferably 5-30mm, and more preferably 10-20mm, most preferably is 15mm.
The rat heart perfusion fixture that this utility model is above-mentioned, wherein, presss from both sides leaf partial-length and is preferably 5-20mm in described clip, more preferably 10-15mm, most preferably is 13mm; Jig arm partial-length is preferably 5-20mm, and more preferably 8-15mm, most preferably is 10mm.
The rat heart perfusion fixture that this utility model is above-mentioned, wherein, the length of catheter needle holder is preferably 20-60mm, and more preferably 30-50mm, most preferably is 40mm; The distance of fastener and syringe needle front end is preferably 10-30mm, and more preferably 15-25mm, most preferably is 20mm; Needle length is preferably 10-20mm, and more preferably 12-18mm, most preferably is 15mm.
In the absence of special instruction, in the application's foregoing, in clamp holder, press from both sides leaf and partly refer in clamp holder, take jointed shaft as boundary for clamping the part of heart, jig arm is partly with respect to another part of folder leaf part in clamp holder; Described adjustable column bottom refers to adjustable column and jig arm coupling part.
Above-mentioned technical scheme tool has the following advantages or beneficial effect:
The rat heart perfusion fixture that this utility model provides, preparation is simple, easy to operate, can effectively reduce catheter needle in operation inserts unsuccessfully, piercing through heart causes perfusion incomplete, catheter needle is fixed the situation generations such as not good enough, the length of perfusion fixture and angle design can guarantee that heart obtains good fixing, catheter needle effectively makes to pour into syringe needle end through heart parietal layer and is finally positioned at ventricle chamber pars intermedia, adverse events occurs to have avoided puncture failure and puncture etc., and due to easy and simple to handle, abecedarian easily grasps, significantly improved the success rate of heart perfusion.
Accompanying drawing explanation
Fig. 1 is the structural representation of facing of an embodiment of rat heart perfusion fixture;
Fig. 2 is the forward sight structural representation of an embodiment of rat heart perfusion fixture;
Fig. 3 is the backsight structural representation of an embodiment of rat heart perfusion fixture.
The specific embodiment
By accompanying drawing, a kind of preferred forms of the present utility model is described below:
Embodiment mono-:
As shown in Figure 1, a kind of rat heart perfusion fixture, comprise clip 1, catheter needle holder 2 and catheter needle 3, wherein, clip 1 comprises two clamp holders 11, jointed shaft 12 and spring 13, in the middle of two clamp holders 11, by jointed shaft 12, connect, jointed shaft two ends clamp holder 11 is divided into folder leaf part 111 and jig arm part 112, and folder leaf part 111 length are 13mm; Jig arm part 112 length are 10mm, in two clamp holders 11, between jig arm 111, are connected with spring 13.
As shown in Figure 2, the rat heart perfusion fixture that this utility model provides is to make according to the actual anatomic parameter of rat heart, the pipe that described catheter needle holder 2 is both ends open, holder length is 25mm, described jointed shaft 12 mid-porose 121, in described hole 121, penetrate catheter needle holder 2, catheter needle 3 comprises syringe needle 33, backshank 31 and fastener 32, and fastener 32 is arranged on backshank 31 1 sides.
As shown in Figure 2; described catheter needle 3 can insert catheter needle holder 2, and can extend to press from both sides in two clamp holders 11 and in 111, two clamp holders of leaf part, press from both sides leaf 111 inner sides and be provided with rubbing surface 15; make to press from both sides leaf and clamp heart and be difficult for slippage, also cardioprotection tissue is without prejudice simultaneously.
As shown in Figure 3, catheter needle holder 2 is with opening 21, one end of the close jointed shaft of opening 21 is provided with draw-in groove 22, draw-in groove 22 is 15mm with the distance of jointed shaft 12 mesopores 121, be used for blocking the fastener 32 on catheter needle 3, described fastener 32 can slide along the opening 21 on catheter needle holder 2 and be stuck in described draw-in groove 22, and the length of catheter needle holder 2 is preferably 40mm; Fastener 32 is preferably 20mm with the distance of syringe needle 33 front ends; Syringe needle 33 length are 15mm.
In experiment, after rat anesthesia, lie on the back fixing, open abdomen, open breast, hemostasis clamp xiphoid-process, shears is cut off along the breastbone left and right sides, before thorax, turns over, and fully exposes thoracic cavity, sees the heart of beating.Pick out behind left ventricle position, open front end fixation clamp, along apex of the heart stringer clamp heart.Catheter needle backshank 31 is connected with tube for transfusion by threeway.The catheter needle holder 2 insertion hearts of the catheter needle 3 of tube for transfusion along tubulose will be connected with, rear rotary pouring pin fastener 32 is stuck in draw-in groove 22 places of catheter needle holder 2, after cut off postcava, superior vena cava or cut off right auricle, open venous blood, open tube for transfusion, carry out heart perfusion.
Embodiment bis-:
On the basis of embodiment mono-, in the present embodiment, also comprise adjustable column and adjusting nut, adjustable column is arranged in a described jig arm and is enclosed within described spring, adjustable column bottom arranges adjusting nut, described adjustable column and adjusting nut capable of regulating spring pressure, make clip can clamp more closely heart.
The rat heart perfusion fixture that this utility model provides, preparation is simple, easy to operate, can effectively reduce catheter needle in operation inserts unsuccessfully, piercing through heart causes perfusion incomplete, catheter needle is fixed the situation generations such as not good enough, the length of perfusion fixture and angle design can guarantee that heart obtains good fixing, catheter needle effectively makes to pour into syringe needle end through heart parietal layer and is finally positioned at ventricle chamber pars intermedia, adverse events occurs to have avoided puncture failure and puncture etc., and due to easy and simple to handle, abecedarian easily grasps, significantly improved the success rate of heart perfusion.
Above specific embodiment of the utility model be have been described in detail, but it is as example, this utility model is not restricted to specific embodiment described above.To those skilled in the art, any equivalent modifications that this practicality is carried out and alternative also all among category of the present utility model.Therefore,, not departing from the equalization conversion of doing under spirit and scope of the present utility model and revising, all should be encompassed in scope of the present utility model.
Claims (10)
1. a rat heart pours into fixture, it is characterized in that, comprise clip and catheter needle holder, wherein, clip comprises two clamp holders, jointed shaft and springs, in the middle of two clamp holders, by jointed shaft, connects, and take jointed shaft as boundary, clamp holder is divided into folder leaf part and jig arm part, in two clamp holders, between jig arm, is connected with spring;
The pipe that described catheter needle holder is both ends open, is provided with the hole of running through described jointed shaft in described jointed shaft, region between region and jig arm part between described hole connection folder leaf part, and catheter needle holder is communicated with described hole.
2. rat heart according to claim 1 perfusion fixture, is characterized in that, catheter needle fixedly on wall with at least one opening.
3. rat heart perfusion fixture according to claim 2, is characterized in that, at least one end of opening is provided with draw-in groove.
4. rat heart perfusion fixture according to claim 3, is characterized in that, the distance of described draw-in groove and jointed shaft mesopore is 5-30mm.
5. according to the rat heart perfusion fixture described in any one in claim 3-4, it is characterized in that, comprise catheter needle, described catheter needle can insert catheter needle holder, and can extend in two clamp holders and press from both sides leaf part.
6. rat heart perfusion fixture according to claim 5, is characterized in that, catheter needle comprises syringe needle, backshank and fastener, and fastener is arranged on backshank one side, and described fastener can slide along the opening on catheter needle holder and be stuck in described draw-in groove.
7. rat heart perfusion fixture according to claim 5, is characterized in that, described catheter needle backshank is connected with tee T.
8. rat heart perfusion fixture according to claim 1, is characterized in that, presss from both sides leaf side in opposite directions and be provided with rubbing surface in two clamp holders.
9. rat heart perfusion fixture according to claim 1, is characterized in that, catheter needle holder length is 10-40mm.
10. rat heart perfusion fixture according to claim 1, is characterized in that, in described clip, pressing from both sides leaf partial-length is 5-20mm, and jig arm partial-length is 5-20mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320423889.5U CN203425059U (en) | 2013-07-17 | 2013-07-17 | Rat heart perfusion fixation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320423889.5U CN203425059U (en) | 2013-07-17 | 2013-07-17 | Rat heart perfusion fixation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203425059U true CN203425059U (en) | 2014-02-12 |
Family
ID=50054124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320423889.5U Expired - Fee Related CN203425059U (en) | 2013-07-17 | 2013-07-17 | Rat heart perfusion fixation device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203425059U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104644284A (en) * | 2015-02-26 | 2015-05-27 | 中国人民解放军第二军医大学 | Small animal perfusion sampling fixing device and small animal perfusion sampling fixing method |
| CN107049553A (en) * | 2017-05-11 | 2017-08-18 | 西安医学院 | Zoopery catheter needle |
| CN111345904A (en) * | 2020-02-28 | 2020-06-30 | 同济大学 | Heart fixing device for small animal heart confocal imaging |
| CN113413233A (en) * | 2021-06-18 | 2021-09-21 | 河南中医药大学第一附属医院 | Injection needle for heart liquid perfusion of small animals |
-
2013
- 2013-07-17 CN CN201320423889.5U patent/CN203425059U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104644284A (en) * | 2015-02-26 | 2015-05-27 | 中国人民解放军第二军医大学 | Small animal perfusion sampling fixing device and small animal perfusion sampling fixing method |
| CN107049553A (en) * | 2017-05-11 | 2017-08-18 | 西安医学院 | Zoopery catheter needle |
| CN111345904A (en) * | 2020-02-28 | 2020-06-30 | 同济大学 | Heart fixing device for small animal heart confocal imaging |
| CN113413233A (en) * | 2021-06-18 | 2021-09-21 | 河南中医药大学第一附属医院 | Injection needle for heart liquid perfusion of small animals |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN203425059U (en) | Rat heart perfusion fixation device | |
| US7060060B1 (en) | Dialysis procedure catheter | |
| CN214259431U (en) | Guide wire introducing cannula for cardiovascular interventional therapy | |
| CN211534712U (en) | Disposable safety internal fistula cannula puncture needle | |
| AU2016294904A1 (en) | Ovum collection needle | |
| CN205988321U (en) | Lower pair of loop fixed locator of dislocation of shoulder arthroscope | |
| CN205072922U (en) | Damaged plugging device of heart membranous part of interventri cular septum | |
| CN207804291U (en) | A kind of traction fixator with positioning device | |
| CN203075346U (en) | Infant intra-arterial infusion syringe needle | |
| CN204951020U (en) | Heart atrial septal defect plugging device | |
| CN205251746U (en) | Perfusion fixing device that can freely support | |
| CN206507988U (en) | Aorta anastomosis device | |
| CN205054307U (en) | Minimally invasive scalp retractor | |
| CN213189972U (en) | Clinical piercing depth that uses of cardiothoracic surgery | |
| CN201543042U (en) | Needle head for limiting and preventing inserting needle of disposable infusion set from shifting | |
| CN213466343U (en) | Disposable transfusion system steel needle easy to fix | |
| CN203003983U (en) | Hot air type perforating machine | |
| CN205612499U (en) | Board -like fixer of percutaneous kidney aspiration biopsy art | |
| CN218885929U (en) | Heart perfusion system for animal heart perfusion experiment | |
| CN219071580U (en) | Needle device is reserved in neck is fixed | |
| CN202761398U (en) | Enterocoelia end puncture needle for cerebral ventricle enterocoelia split-flow | |
| CN204147404U (en) | The multi-cavity drainage system that can subcutaneously move under water | |
| CN217908510U (en) | Needle is kept somewhere to disconnect-type | |
| CN218833118U (en) | Operation frame convenient to it is fixed | |
| CN203861648U (en) | Arm or leg fixing support plate used for hemodialysis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140212 Termination date: 20190717 |